Exhibit 10


                                     CONFIDENTIAL
                                     ------------

          1.   This Agreement is made this 27th day of August 1996 among:

               (A)  Chiron Corporation of 4560 Horton Street, Emeryville,
                    California, United States of America ("Chiron
                    Corporation") on its behalf and on behalf of its
                    Affiliates (collectively "Chiron").

               (B)  Johnson & Johnson/Ortho Diagnostics Systems Inc. of
                    Route 202 Raritan, New Jersey, United States of America
                    ("ODSI") on its behalf and on behalf of its Affiliates
                    (collectively "Ortho").

               (C)  International Murex Technologies Corporation of Du
                    Moulin Black, 10th Floor, 595 Howe Street, Vancouver,
                    BC, V6C2T5, Canada ("IMTC") on its behalf and on behalf
                    of its Affiliates (collectively "Murex").

               (D)  Chiron Corporation, ODSI and IMTC are collectively the
                    "Parties".

          2.   The following terms bear the following meanings for the
               purposes of this Agreement:

               "Affiliate" means, with respect to any specified Person, any
               other Person who or which directly, or indirectly through
               one or more intermediaries or otherwise, is controlled by,
               or is under common Control with such specified Person. 
               "Control" means, as to any Person, the ability, whether
               exercised or not, to direct or to influence, directly or
               indirectly the management, affairs, policies or business
               practices of such Person, whether through the ownership of
               securities, through contract or other agreement, through
               proxy or other instrument, through a course of conduct or a
               business relationship, or otherwise.  Without limiting the
               generality of the foregoing, a Person shall conclusively be
               deemed to have the "ability" to "direct or to influence" the
               "management, affairs, policies, or business practices" of
               another Person if (i) such Person, or an Affiliate of such
               Person, "beneficially owns" (within the meaning of Rule 13d-
               3 under the Securities Exchange Act of 1934, as amended)
               twenty percent (20%) or more of any class of securities of
               the other Person, or (ii) such Person, or an Affiliate of
               such Person, has the ability, directly or indirectly, and
               whether exercised or not, through the ownership of
               securities, through contract or other agreement, through
               proxy or other instrument, or otherwise, to elect or
               appoint, or cause the election or appointment of, a
               representative to the Board of Directors, or other similar
               managing body, of the other Person; provided, that
               notwithstanding anything to the contrary contained herein,
               Ciba-Geigy Limited shall not be deemed an "Affiliate" of
               Chiron for purposes of this Agreement.  "Controlled",
               "controlling" and other derivations of "control" shall have
               a correlative meaning.

               "Chiron's HCV Patents" means (a) the patents and patent
               applications (or patents granted pursuant to such
               applications) set out in Schedule 1 hereto, and any
               divisionals, continuations, continuations-in-part, reissues,
               and foreign counterparts thereof, and (b) any other patent,
               patent application, divisional, continuation, continuation-
               in-part, reissue, or foreign counterpart thereof having a
               priority date or an earliest effective patent application
               filing date that is on or before the effective date of this
               Agreement or based upon an invention reduced, to practice
               prior to the date of this Agreement, which is owned or
               controlled with right to sublicense by Chiron or Ortho as of
               the date of this Agreement and which contains a valid claim
               that (i) is specifically directed to HCV antigens, HCV
               antibodies, HCV antigen substitutes, HCV antibody
               substitutes, or immunoassays or kits for the detection,
               typing or determination of HCV, and (ii) is infringed by any
               HCV Product.

     

               "HCV Antibody" means any antibody, or fragment thereof, or
               other anti-ligand immunologically reactive with HCV or a
               portion of HCV and which is used to diagnose or screen for
               hepatitis.

               "HCV Antigen" means any peptide, polypeptide or ligand which
               reacts immnologically with antibodies which are
               immunologically reactive with HCV or a portion of HCV and
               which is used to diagnose or screen for hepatitis.

               "HCV Kit" means the following HCV Products manufactured and
               sold by or on behalf of Murex: VK45, VK46, VK47, VK48, VK68,
               HC01 and HC02.

               "HCV Product" means each immunoassay, immunoassay kit or
               immunoassay test configuration, the manufacture, use or sale
               of which utilise or contains one or more HCV Antigen, HCV
               Antibody, HCV Antigen substitute or HCV Antibody substitute. 
               For purposes of this definition, the term "immunoassay"
               refers to both antigen/ immunoglobulin binding, and other
               ligand/anti-ligand binding phenomena, excluding nucleic acid
               hybridisation.  The term "HCV Product" includes, without
               limitation, HCV Kits, HCV ELISA test kits, HCV Western blot
               kits, HCV immunoblot kits, HCV serotyping immunoassay kits,
               agglutination assays, radioimmunoassays, and the like.

               "Licensed Subsidiary" means any corporation, partnership
               (general or limited), limited liability company or joint-
               stock company of which IMTC owns, directly or indirectly,
               more than fifty percent (50%) of the voting and
               participating profit interests.

               "Person" means any individual, corporation, partnership
               (general or limited), limited liability company, limited
               liability partnership, firm, joint venture, association,
               company, affiliation, joint-stock company, trust, estate,
               unincorporated organisation, governmental or regulatory
               body, or any other entity, association, organisation, or
               vehicle of any type whatsoever.

               "The UK Proceedings" means the infringement proceedings
               relating to infringement of UK Patent No. 2,212,511, Action
               Numbers CH 1992 C No 1513 and CH 1993 C No. 6942.

               The "Dutch Proceedings" mean proceedings:  in the District
               Court in The Hague, docket No. 96/1034; in the Court of
               Appeals in The Hague, docket No. 95/0813, appeal by SDL to
               the Decision of the President of The Hague District Court of
               8 May 1995; and in the Supreme Court of The Netherlands,
               docket No. 16.206, appeal in caseation, filed by SDL against
               the Decision of the Court of Appeals in The Hague of 7
               December 1995.

               The "German Proceedings" mean infringement proceedings in
               the District Court in Dusseldorf, official file number 4 0
               357/93 and in the Higher Regional Court in Dusseldorf,
               official file number 2 U 12/95, and nullity proceedings in
               the Federal Court of Munich, official file number 3 Ni
               40/94.

               The "Italian Proceedings" mean the proceedings between
               Chiron Corporation, ODSI and Murex Diagnostic S.p.A and Alfa
               Biotech S.p.A. in the Court of Rome General Register No.
               58441/94.

               The "Belgian Proceedings" mean the appeal by Murex
               Diagnostics N.V. against the decision of the Judge of
               Seizures of Dendermonde of February 24th 1995.

               The "Australian Patent Infringement Proceedings" mean
               Proceedings No. G1 06 of 1994 commenced in the Federal Court
               of Australia, New South Wales District Registry, General
               Division.

     

               The "Australian Anti-Trust and Compulsory Licence
               Proceedings" mean Proceedings No. G380 of 1996 in the
               Federal Court of Australia, New South  Wales District
               Registry, General Division.

               Save where the context otherwise requires words importing
               the singular number include the plural and vice versa.

          3.   IMTC on behalf of Murex agrees to pay Chiron on behalf of
               Chiron and Ortho the sum [                     ].

          4.   Subject as otherwise provided herein:

               (a)  Chiron and Ortho severally agree, undertake and
                    covenant to indemnify and hold Murex its directors,
                    officers, employees, distributors, servants, partners
                    and agents, together with their heirs, executors
                    administrators, successors and assigns, harmless and
                    free from liability and suit, including all costs,
                    damages, expenses and liabilities whatsoever (including
                    legal expenses when incurred) arising out of any claim
                    by any other licensee of Chiron's HCV Patents or any
                    Chiron collaborator relating to any past or current
                    infringement of Chiron's HCV Patents by Murex, its
                    directors, officers, employees, distributors, servants,
                    partners or agents.

               (b)  Chiron and Ortho each hereby releases and discharges
                    Murex its directors, officers, employees, distributors,
                    servants, partners and agents together with their
                    heirs, executors, administrators, successors and
                    assigns for all actions, causes of action, suits,
                    debts, dues, sums of money, accounts, reckonings,
                    bonds, bills, specialities, covenants, contracts,
                    controversies, agreements, obligations, promises,
                    variances, trespasses, damages, judgements, extents,
                    executions, claims and demands whatsoever, in law,
                    admiralty or equity, whether known or unknown, which
                    Chiron or Ortho, or their successors and assigns, ever
                    had, now have or hereafter can, shall, or may have
                    against Murex and the other parties described above,
                    with respect to or arising out of Chiron's HCV Patents,
                    including such litigation and proceedings specifically
                    listed in clause 7 below, from the beginning of the
                    world to and including the day of the date of this
                    Agreement.

               (c)  Murex hereby releases and discharges Chiron and Ortho
                    and their respective directors, officers, employees,
                    distributors, servants, licensees, partners and agents
                    together with their heirs, executors, administrators,
                    successors and assigns for all actions, causes of
                    action, suits, debts, dues, sums of money, accounts,
                    reckonings, bonds, bills, specialities, covenants,
                    contracts, controversies, agreements, promises,
                    obligations, variances, trespasses, damages,
                    judgements, extents, executions, claims and demands
                    whatsoever, in law, admiralty or equity, whether known
                    or unknown, which Murex, or its successors and assigns,
                    ever had, now have or hereafter can, shall, or may have
                    against Chiron or Ortho or the other parties described
                    above, arising out of or relating to Chiron's HCV
                    Patents, including such litigation and proceedings
                    specifically listed in clause 7 below, from the
                    beginning of the world to and including the day of the
                    date of this Agreement.

               (d)  In the event that Alfa Biotech S.p.A. ("Alfa") notifies
                    Chiron and Ortho that they wish to discontinue their
                    involvement in the Italian Proceedings, Chiron and
                    Ortho will release Alfa on terms similar to those

     -----------------
           * Brackets denotes where information was deleted due to the 
     confidential nature of the material.

     
                    contained in subclause (d) above upon receipt of a
                    release from Alfa on terms similar to those contained
                    in subclause (c) above.

          5.   [Reserved]

          6.   IMTC shall obtain the agreement of the joint liquidators of
               Specialist Diagnostics Limited (in liquidation) ("SDL"): (a)
               to withdraw SDL's petition for leave to appeal to the House
               of Lords in the UK proceedings, (b) to terminate SDL's
               involvement in and to abandon any of SDL's claims related to
               any of the proceedings listed below in clause 7 and (c) to
               terminate SDL's involvement in any opposition to Chiron's
               European Patent No 318216 by foregoing any appeal of the
               Opposition Division's decision and filing an express
               abandonment of its opposition all of which shall be
               evidenced by the delivery to Chiron Corporation of a letter
               from the joint liquidators in a form reasonably satisfactory
               to Chiron and Ortho, subject only to delivery by or on
               behalf of Chiron and Ortho of the confirmation referred to
               in Clause 11 below.

          7.   Chiron Corporation and ODSI shall apply simultaneously with
               the joint liquidators of SDL to withdraw their petition for
               leave to appeal to the House of Lords in the UK Proceedings. 
               Further the Parties shall procure the prompt and permanent
               termination on the terms set out below in this clause 7 of:-

               (a)  the UK Proceedings;

               (b)  the European Patent Office Proceedings in respect of
                    Chiron's EP patent 318216;

               (c)  the Dutch Proceedings;

               (d)  the German Proceedings;

               (e)  the Italian Proceedings (other than as to Alfa, unless
                    Alfa elects to enter into cross-releases with Chiron
                    and Ortho as provided in clause 4(d));

               (f)  the Belgian Proceedings;

               (g)  the Australian Patent Infringement Proceedings and any
                    and all opposition to Chiron HCV Patents in Australia;

               (h)  the Australian Anti-Trust and Compulsory Licence
                    Proceedings;

               (i)  any other proceeding (whether current, pending or
                    threatened) whatsoever or wheresoever concerning
                    Chiron's HCV Patents (including, but not limited to,
                    proceedings in which validity, infringement,
                    inventorship or licensing are at issue) involving
                    Murex, its directors, officers, employees,
                    distributors, servants, licensees, partners or agents;

          and in all cases such termination shall be on the basis that:

          (i)       all orders for costs outstanding shall be deemed
                    discharged;

          (ii)      there shall be no further provision for the payment of
                    money or costs or the granting of other relief whether
                    legal or equitable;

          (iii)     any court or tribunal or registry or like fees required
                    to be paid to bring about the termination shall be met
                    equally by Chiron Corporation and/or ODSI on the one
                    hand and IMTC on the other;

          (iv)      All injunctions will remain outstanding and fully
                    enforceable by Chiron and Ortho; provided that Chiron

     

                    and Ortho agree not to enforce such injunctions unless
                    the arbitrators, in accordance with the arbitration
                    provisions of clause 17 of this Agreement, have
                    determined that Murex is in breach of this Agreement
                    and that injunctive relief is appropriate.

          8.   Murex will not itself, directly or indirectly, actively
               participate in or initiate (or assist any Person in
               participating in or initiating) any proceedings or
               investigations arising in any way from the alleged
               licensing, pricing or business policies of Chiron and Ortho
               relating to Chiron's HCV Patents provided that nothing
               herein shall prevent Murex responding to any lawful requests
               for information from any relevant investigating authority
               referenced in clause 13 or from enforcing the provisions of
               this Agreement in accordance with its terms.

          9.   Neither Chiron nor Ortho will wilfully make or assist any
               Person in making any untrue statement, whether written or
               oral, disparaging Murex's HCV Products that materially,
               adversely impacts the HCV immunodiagnostics business of
               Murex, and Murex will not wilfully make or assist any Person
               in making any untrue statement, whether written or oral,
               disparaging Chiron' s or Ortho's HCV Products that
               materially, adversely impacts the HCV immunodiagnostics
               business of Chiron or Ortho.  In the event that either
               Chiron or Ortho, on the one hand, or Murex, on the other,
               seeks to contend that other party is in material breach of
               the foregoing provision written notice to that effect shall
               be delivered to the President of the other parties setting
               out in detail the particulars of the alleged breach.  In the
               event that Chiron or Ortho, on the one hand, or Murex, as
               the case may be, shall assert that the other party
               thereafter has wilfully persisted in the breach and has
               failed within 30 days of receipt of written notice to take
               immediate and reasonable measures to bring the breach to an
               end, then the provisions of clause 17 below as to
               arbitration shall apply, and if the arbitrators determine
               that Chiron, Ortho, or Murex is in wilful material breach of
               such provision, the arbitrators shall award such damages or
               equitable relief as they determine appropriate.  Such
               arbitral award shall be the aggrieved party's sole remedy
               for breach of this provision.

          10.  In the event that, despite Murex's compliance with clause 8
               above and clause 13 below, the European Commission or other
               competent authority deems Chiron's HCV Patents to be an
               essential facility or technology that must be freely
               licensed, Murex will not be barred by virtue of this
               Agreement from seeking a licence from Chiron and Ortho and
               Chiron and Ortho shall not unreasonably discriminate against
               Murex in awarding any such license.

          11.  Upon the obtaining of the joint liquidators' agreement
               pursuant to clause 6 above, Chiron and Ortho shall forthwith
               withdraw their claims in the liquidation of SDL and release
               to the joint liquidators of SDL the sum of [       ] held by
               Bristows Cooke and Carpmael in respect of costs in the UK
               Proceedings and shall give a confirmation to the joint
               liquidators in such form as they shall reasonably require.

          12.  It is further agreed that:

               (a)  Save as permitted by clauses 15 and 16 Murex will not
                    henceforth infringe any of Chiron's HCV Patents in the
                    following territories (the "Excluded Territories"):
                    Japan, USA, Canada, Mexico, Switzerland, Norway,
                    Iceland and Liechtenstein and all the current countries
                    of European Union which, for the avoidance of any
                    doubt, are listed at Schedule 2.

               (b)  For territories other than the Excluded Territories set
                    out above (the "Permitted Territories"), Chiron and
                    Ortho grant to IMTC and the Licensed Subsidiaries a
                    non-exclusive license under Chiron's HCV Patents for
                    the life of Chiron's HCV Patents to make, have made,

     

                    use and sell HCV Products in the Permitted Territories. 
                    The grant of such license shall be further evidenced by
                    a license agreement to be agreed upon by the parties   
                    [          ], which license agreement shall include the
                    following economic terms:

                         (i)  For the first seven years, IMTC, on behalf of
                         IMTC and the Licensed Subsidiaries, shall pay to
                         Chiron, on behalf of Chiron and Ortho, a [      ]   
                         commencing September 30, 1996.

                         (ii) In year seven and thereafter, IMTC, on behalf
                         of IMTC and Licensed Subsidiaries shall pay to
                         Chiron, on behalf of Chiron and Ortho, a royalty
                         on sales of all HCV Kits and all other HCV
                         Products which are covered by a Chiron HCV Patent
                         in countries in which a Chiron HCV Patent is
                         issued to Chiron[       ].  Such license be non-
                         transferable and not subject to sublicense, and
                         shall include warranties, representations, and
                         indemnities typical of such licenses.  For the
                         avoidance of doubt: in year seven, and only year
                         seven, royalties shall be payable under both
                         subclauses (i) and (ii) of this clause 12(b).

                         (iii)  Notwithstanding anything to the contrary
                         contained in this clause 12(b), during the first
                         six years of this Agreement the royalty payable on
                         sales to an unaffiliated third parties of HCV
                         Products in [     ].  Thereafter the royalty will
                         be[      ].  During the first six years of this
                         Agreement, such royalty shall be creditable
                         against royalties owed under clause 12(b)(i).

               (c)  Effective immediately and continuing until such time as
                    such license agreement is executed, Chiron and Ortho
                    and their successors and assigns, on the same economic
                    terms applicable to a license under clause 12(b)(i) and
                    (ii), grant to IMTC and the Licensed Subsidiaries and
                    their distributors and agents and their respective
                    directors, officers, employees, executors,
                    administrators, successors and assigns immunity from
                    suit for infringement, liability for damages or
                    compensation and for all actions, causes of action,
                    suits, debts, dues, sums of money, accounts,
                    reckonings, bonds, bills, specialities, obligations
                    covenants, contracts, controversies, agreements,
                    promises, variances, trespasses, damages, judgements,
                    extents, executions, claims and demands whatsoever, in
                    law, admiralty or equity, whether known or unknown,
                    which Chiron or Ortho, or their successors and assigns,
                    ever had, now have or hereafter can, shall, or may have
                    against Murex and the other parties described above,
                    (the "Actions") in respect of Chiron's HCV Patents and
                    relating to the manufacture, use and/or sale of the HCV
                    Kits by Murex in the Permitted Territories for so long
                    as any of Chiron's HCV Patents shall subsist.  Chiron
                    and Ortho agree fully to indemnify IMTC and the
                    Licensed Subsidiaries and their respective directors,
                    officers, employees, distributors, servants, and agents
                    together with the heirs, executors, administrators,
                    successors and assigns harmless and free from liability
                    and suits, including all costs, damages, expenses, and
                    liabilities whatsoever (including reasonable legal
                    expenses when incurred) arising out of any claim by any
                    licensee of Chiron's HCV Patents or any Chiron
                    collaborator of infringement by IMTC or its Licensed
                    Subsidiaries of Chiron's HCV Patents (including but not
                    limited to losses occasioned by the grant of injunctive
                    or similar relief and/or the payment of any monetary
                    compensation).

               (d)  In the event that any territory in the Permitted
                    Territories becomes a member of the European Union or

     

                    the EEA, then such territory will be included in the
                    definition of the Excluded Territories upon payment to
                    IMTC or as it may direct of such amount as it shall
                    certify to be [              ]in respect of HCV
                    Products otherwise permitted under clause (b) above, as
                    follows:
                    [                    ]

               (e)  Murex grants to Chiron and Ortho a non-exclusive,
                    worldwide, fully paid-up, patent and know-how license
                    to any technology owned by Murex relating to or
                    concerning the Sample Addition Monitor.  The grant of
                    such license shall be further evidenced by a license
                    agreement to be agreed in conjunction with the license
                    referred to in clause 12(b).

          13.  Murex will not itself and will not directly or indirectly
               assist any Person to bring or prosecute any proceedings
               relating to the validity, inventorship, ownership, control
               or licensing of any of Chiron's HCV Patents (including the
               compulsory licensing thereof).  Notwithstanding the
               foregoing (or any other provisions of this Agreement), Murex
               shall not be prevented from responding to any lawful
               requests for information from any governmental,
               supragovernmental or other authority which can legally
               require Murex to respond.  In the event that either Chiron
               or Ortho seeks to contend that Murex is in material breach
               of the foregoing provision written notice to that effect
               shall be delivered to the President of IMTC setting out in
               detail the particulars of the alleged breach.  In the event
               that Chiron or Ortho shall assert that Murex thereafter has
               wilfully persisted in such material breach and has failed
               within 30 days of receipt of written notice to take
               immediate and reasonable measures to bring such material
               breach to an end, then the provisions of clause 17 below as
               to arbitration shall apply, and if the arbitrators determine
               that Murex is in wilful material breach of such provision,
               the license (and, if still applicable, freedom from suit)
               granted or to be granted to Murex under clause 12(b) shall
               automatically terminate.

          14.  In the event that Murex seeks to contend that Chiron or
               Ortho is in wilful material breach of clause 12(b) or the
               license granted thereunder, written notice to that effect
               shall be delivered to the Presidents of Chiron and Ortho
               setting out in detail the particulars of the alleged breach. 
               In the event that Murex shall assert that Chiron or Ortho
               has thereafter wilfully persisted or acquiesced in such
               material breach or has failed within 30 days of receipt of
               written notice to take immediate and reasonable measures to
               bring such material breach to an end, the provisions of
               clause 17 shall apply and if the arbitrators determine that
               Chiron or Ortho is in wilful material breach of clause 12(b)
               or the license granted thereunder, the license granted to
               IMTC and the Licensed Subsidiaries under clause 12(b) shall
               thereafter be [     ] effective from the date of such wilful
               material breach.

          15.  It is further agreed that:

               (a)  Chiron and Ortho grant to IMTC and the Licensed
                    Subsidiaries a world-wide non-exclusive licence, which
                    shall be non-transferable and without the right to
                    grant sublicenses, under Chiron's HCV Patents to make,
                    have made, use and sell HCV Products for determining
                    HCV serotypes for the life of such patents, such
                    licence bearing a royalty rate of [        ] of all
                    such products sold by IMTC and the Licensed
                    Subsidiaries, provided, however, that in the event
                    Chiron and Ortho elect to enter into an agreement for
                    the worldwide private label sale of Murex's HCV
                    serotyping products, such license shall be [        ]
                    and the agreement for such private label sale shall
                    provide that Murex shall sell such HCV serotyping
                    products to Chiron and Ortho at [           ] to
                    customers purchasing like quantities.  The grant of

     

                    such license shall be further evidenced by a license
                    agreement to be agreed in conjunction with the license
                    referred to in clause 12(b).

                    Chiron and Ortho acknowledge that IMTC and the Licensed
                    Subsidiaries have the right to conduct research and
                    preclinical development related to HCV in the United
                    Kingdom.
                    Murex hereby grants to Chiron and Ortho the right, in
                    their sole discretion, to require IMTC and the Licensed
                    Subsidiaries to take, within two years from the date of
                    this Agreement, a non-exclusive license under Chiron's
                    HCV Patents for the life of such patents to manufacture
                    HCV Products in the United Kingdom for the sole purpose
                    of exporting such HCV Products to the Permitted
                    Territories and with no right to sell, distribute or
                    dispose of such HCV Products to or in the Excluded
                    Territories.  IMTC, on behalf of IMTC and the Licensed
                    Subsidiaries, shall pay to Chiron, on behalf of Chiron
                    and Ortho, [             ].  Such license shall be on
                    the same economic terms as the license granted under
                    clause 12(b).

          16.  In order to enable the smooth transfer of HCV business to
               Ortho or such other supplier as determined by Murex's
               customer, Murex shall be permitted to cease selling its HCV
               Products in the Excluded Territories in a timely and
               efficient manner [       ].  During such transfer period
               Murex will work with Ortho to effect a smooth transfer of
               business including the use of instrumentation used by
               customers to run HCV assays.  Murex shall pay to Chiron on
               behalf of Chiron and Ortho of [                   ].

          17.  Any disagreement or dispute that shall have arisen among the
               parties with respect to this Settlement Agreement must be
               referred to and settled by final and binding arbitration to
               be held in New York, New York, and conducted expeditiously
               in accordance with the Patent Arbitration Rules, as from
               time to time amended and in effect (the "Rules"), of the
               American Arbitration Association ("AAA").  Provided however
                                                          -------- -------
               that notwithstanding the foregoing, nothing contained in
               this Section 17 shall restrict the right of Murex its
               directors, officers, employees, distributors, servants,
               partners or agents to join Chiron and Ortho, or to require
               that Chiron and Ortho be joined, as a party to any action or
               proceeding, brought against Murex or any other indemnitee in
               any forum whatsoever, in respect of which Murex claims a
               right to indemnification under clause 4(a) or 12(b) of this
               Agreement.  Judgement upon award having been rendered by the
               arbitrators may be entered in any court (i) having
               jurisdiction thereof, (ii) having jurisdiction over the
               party against whom enforcement thereof is sought, or (iii)
               having jurisdiction over any such party's assets.  The
               procedures and law applicable during the arbitration of any
               controversy, dispute or claim will be both the Rules and the
               internal laws of the State of New York (excluding, and
               without regard to, its or any other jurisdictions rules
               concerning any conflict of laws).  In any arbitration
               pursuant to this Agreement, the award or decision must be
               rendered by at least a majority of the members of an
               arbitration panel consisting of three (3) members, one of
               whom will be appointed by each of Murex on the one part and
               Chiron and Ortho on the second part and the third of whom
               will be the chairman of the panel and will be appointed by
               mutual agreement of the two party appointed arbitrators. 
               All arbitrators must be persons who are not employees,
               agents, or former employees or agents of any party.  In the
               event of failure of the two party-appointed arbitrators to
               agree within sixty (60) days after submission of the dispute
               to arbitration upon the appointment of the third arbitrator,
               the third arbitrator will be appointed by the AAA in
               accordance with the Rules.  In the event that any of the
               Parties hereto fails to appoint an arbitrator within thirty
               (30) days after submission of the dispute to arbitration,
               such arbitrator, as well as the third arbitrator, will be

     

               appointed by the AAA in accordance with the Rules.  The
               arbitrator shall have the power to issue injunction relief
               for appropriate purposes, including specific performance,
               but shall not award punitive damages.  As part of the
               resolution of the arbitration, the arbitration panel shall
               award reasonable costs to the prevailing party, or apportion
               costs if no party prevails on all issues.

          18.  Confidentiality Provision

               The Parties agree to keep the terms of this Agreement
               confidential with exception of such information which in the
               opinion of counsel to the disclosing party is required to be
               disclosed by applicable law, rule, regulation or generally
               accepted accounting practice, including any rules of
               applicable stock exchanges and other self-regulatory
               authorities or organisations; Provided however that in the
                                             -------- -------
               event a party shall be required to disclose any of the terms
               of this Agreement, whether pursuant to subpoena, deposition,
               interrogatory, or otherwise or a party shall otherwise
               propose to disclose any of the terms of this Agreement
               (except in connection with such party's required disclosures
               under any applicable securities laws, the rules of any
               applicable stock exchange or other self regulatory authority
               or organization or other reporting requirements) such
               disclosing party shall provide the other Parties with prompt
               written notice of such requirement so that the other Parties
               may seek a protective order or other appropriate remedy
               and/or waive compliance with the terms of this Agreement. 
               No prior written notice shall be required in connection with
               any party's required compliance with applicable securities
               laws, the rules of any applicable stock exchange or other
               self-regulatory authority or organization or other reporting
               requirements.  Notwithstanding the foregoing, any party
               shall be permitted to submit this Agreement as evidence in
               any proceeding including, without limitation, any
               notification of this Agreement pursuant to clause 19 below
               or in connection with any dispute between or among the
               Parties.  The provisions of this Clause 18 shall not
               restrict a party from making any disclosure of any terms of
               this Agreement to the extent such terms become generally
               available to the public (other than as a result of a
               disclosure by such party in violation of this Agreement) or
               to the extent such disclosure relates to the right to
               manufacture, market and/or to sell in such territory.

          19.  Chiron and Ortho shall have the right in their discretion to
               notify this Agreement to the European Commission.  Murex
               shall promptly provide any reasonably necessary information
               and perform any reasonably necessary acts upon request to
               permit such notification.

          20.  If one or more provisions contained in this Agreement shall
               be invalid, illegal or unenforceable in any respect under
               any applicable law or regulation the validity, legality and
               enforceability of the remaining provisions shall not be
               affected or impaired in any way.  The Parties to this
               Agreement shall replace the aforementioned invalid, illegal
               or unenforceable provisions by valid, legal and enforceable
               provisions as close in terms as possible to the replaced
               provisions so as to take effect from the date hereof.  In
               the event the Parties cannot agree on the terms of such
               replacement provisions, such replacement provisions will be
               determined by arbitration as provided herein.

          21.  Schedule 4 sets out the form of agreed Press Release as an
               exception to the general confidentiality provisions.

          22.  Each party warrants that it has any and all necessary power
               to enter into this Agreement, both for it and its
               Affiliates.

          23.  Remedies and Waivers

               No delay or omission on the part of the Parties in
               exercising any right, 
               
               
     
               power, or remedy (whether in whole or in part) under this 
               Agreement shall:

               (i)  impair such right, power or remedy; or

               (ii) operate as a waiver thereof.

          24.  Further Assurance

               Each of the Parties shall, from time to time on being
               required to do so by another, now or at any time in the
               future, do or procure the doing of all such acts and/or
               execute or procure the execution of all such documents in a
               form satisfactory to the others as may reasonably be
               considered necessary for giving full effect to this
               Agreement.

          25.  Entire Agreement

               This Agreement contains the entire agreement of the Parties
               regarding the subject matter hereof and supersedes all prior
               agreements, understandings and negotiations regarding the
               same.  The Parties acknowledge that there have been various
               statements, both oral and written, pertaining to the making
               of this Agreement and the Parties' performance hereunder. 
               The Parties agree that none of them has relied on any such
               statements, but instead have relied upon the representations
               and warranties explicitly set forth herein.  This Agreement
               may not be changed, modified, amended or supplemented except
               by a written instrument signed by the Parties hereto.

          26.  This Agreement shall be governed by the law of New York,
               USA, without regard to its conflict of law provisions. 
               Infringement shall be governed by the law of the country in
               which infringement is at issue.

          27.  Change in Control

               In the event that IMTC experiences one or more of the
               following events (a "Change in Control"):

                    (i)  Any person or group (other than Chiron or Ortho or
                    a group including one of them or a Person owning more
                    than five percent of the combined voting power of Murex
                    as of the date hereof, as described in Schedule 3
                    hereto) becomes, or makes an offer to become, after the
                    date hereof, whether by tender or exchange offer or
                    otherwise the beneficial owner, directly or indirectly,
                    of securities of IMTC representing 50% or more of the
                    combined voting power of IMTC's then outstanding voting
                    securities; or

                    (ii) The Board of Directors of IMTC approve a plan of
                    merger, consolidation, or liquidation (which would not
                    result in IMTC being the continuing entity) or the sale
                    or disposition of all or substantially all of IMTC's
                    assets,

               then, IMTC shall promptly notify Chiron and Ortho in
               writing, describing such event in reasonable detail and
               shall offer Chiron and Ortho the option, to be exercised in
               writing within fifteen (15) business days to purchase at
               fair value the HCV immunoassay business of IMTC, such value
               to take into account, among other things, I the diminution
               in value of IMTC's overall business without, or the loss of
               the opportunity to sell, the HCV immunoassay business.

          28.  Assignment

               No party shall be entitled to assign its rights as a
               licensee under this Agreement without the prior written
               consent of the other parties hereto; provided, however, that
               any party may assign its rights as a licensee, subject to

     

               clause 27, (i) a Person into which such party shall merge or
               consolidate or (ii) a Person who acquires all or
               substantially all of such party's assets. 

     


          AGREED BY

          CHIRON CORPORATION
          By:   /s/ Edward E. Penhote
             ------------------------------- 
          Title:

          JOHNSON & JOHNSON
          By:   /s/ S      Harris       
             -------------------------------
          Title: Asst. Secy./Gen. Counsel

          ORTHO DIAGNOSTIC SYSTEMS INC.
          By:   /s/ J. W.                      
             -------------------------------
          Title: President

          INTERNATIONAL MUREX TECHNOLOGIES CORPORATION
          By:   /s/ F. Michael P. Warren              /s/ C. Robert Cusick
             -------------------------------          CFO
          Title: Chairman