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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                     FORM 15

CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(G) OF
THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER
SECTIONS 13 AND 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934


                                                  Commission File Number 0-22510


                            CLINTRIALS RESEARCH INC.
             (Exact name of registrant as specified in its charter)

                              11000 Weston Parkway
                           Cary, North Carolina 27513
                                 (919) 462-2556

(Address, including zip code, and telephone number, including area code of
registrant's principal executive offices)


                                  Common Stock
                            $.01 par value per share
            (Title of each class of securities covered by this Form)


                                      None

         (Titles of all other classes of securities for which a duty to file
reports under section 13(a) or 15(d) remains)


         Please place an X in the box(es) to designate the appropriate rule
provision(s) relied upon to terminate or suspend the duty to file reports:

    Rule 12g-4(a)(1)(i)       |X|                 Rule 12h-3(b)(1)(i)       |X|
    Rule 12g-4(a)(1)(ii)      |_|                 Rule 12h-3(b)(1)(ii)      |_|
    Rule 12g-4(a)(2)(i)       |_|                 Rule 12h-3(b)(2)(i)       |_|
    Rule 12g-4(a)(2)(ii)      |_|                 Rule 12h-3(b)(2)(ii)      |_|
                                                  Rule 15d-6                |_|

         Approximate number of holders of record as of the certification or
notice date: 1

         Pursuant to the requirements of the Securities Exchange Act of 1934,
ClinTrials Research Inc. has caused this certification/notice to be signed on
its behalf by the undersigned duly authorized person.

                                                     CLINTRIALS RESEARCH INC.


Date:      APRIL 6, 2001                              By: /S/ WALTER S. NIMMO
           -------------                                  ----------------------
                                                          Name:  Walter S. Nimmo
                                                          Title: President