UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 14A

          PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES
                              EXCHANGE ACT OF 1934

Filed by the Registrant [X]

Filed by a Party other than the Registrant [ ]

Check the appropriate box:

<Table>
                                            
[ ]  Preliminary Proxy Statement
[ ]  Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
[X]  Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to sec.240.14a-12
</Table>

                          IMCLONE SYSTEMS INCORPORATED
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

[X]  No fee required

[ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

     (1)  Title of each class of securities to which transaction applies:

        ------------------------------------------------------------------------

     (2)  Aggregate number of securities to which transaction applies:

- --------------------------------------------------------------------------------

     (3)  Per unit price or other underlying value of transaction computed
          pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
          filing fee is calculated and state how it was determined):

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     (4)  Proposed maximum aggregate value of transaction:

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     (5)  Total fee paid:

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[ ]  Fee paid previously with preliminary materials.

[ ]  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the filing for which the offsetting fee was paid
     previously. Identify the previous filing by registration statement number,
     or the Form or Schedule and the date of its filing.

     (1)  Amount Previously Paid:

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     (4)  Date Filed:

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                                 [IMCLONE LOGO]

                          IMCLONE SYSTEMS INCORPORATED
                               180 Varick Street
                               New York, NY 10014
                                 (212) 645-1405

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

                           DATE:  September 15, 2003
                         TIME:  10:00 A.M. (Local Time)
                      PLACE:  ImClone Systems Incorporated
                                  33 Chubb Way
                          Somerville, New Jersey 08876

ITEMS OF BUSINESS:

     1. Election of five directors.

     2. Approval of an amendment to the ImClone Systems Incorporated 2002 Stock
        Option Plan (the "2002 Option Plan") to increase the number of shares
        authorized to be issued under the 2002 Option Plan.

     3. Approval of the ImClone Systems Incorporated Annual Incentive Plan (the
        "Annual Incentive Plan").

     4. Ratification of the appointment of KPMG LLP as the Company's independent
        certified public accountants for the fiscal year ending December 31,
        2003.

     5. Any other matters properly brought before the stockholders at the
        meeting.

RECORD DATE:

     Only holders of the common stock of record at the close of business on
August 20, 2003 are entitled to notice of and to vote at the meeting or any
postponements or adjournments thereof.

ANNUAL REPORT:

     The Company's 2002 Annual Report on Form 10-K, which is not a part of the
proxy soliciting material, is enclosed.

PROXY VOTING:

     It is important that your shares be represented and voted at the meeting.
To vote, please complete, sign and date the enclosed proxy and promptly return
it in the envelope provided or submit your vote by telephone or via the
Internet. Sending in your proxy will not prevent you from voting in person at
the meeting.

                                          By Order of the Board of Directors

                                          /s/ Michael J. Howerton
                                          Michael J. Howerton
                                          Secretary

New York, New York
August 21, 2003


                               TABLE OF CONTENTS

<Table>
                                                             
ABOUT THE MEETING...........................................      1
What is the purpose of the meeting?.........................      1
Who may attend the meeting?.................................      1
Who is entitled to vote?....................................      1
What constitutes a quorum?..................................      1
What vote is required to approve each item?.................      2
What are the recommendations of the Board of Directors?.....      2
How do I vote?..............................................      2
What if I am a beneficial owner rather than a holder of
  record?...................................................      2
If I hold my shares in a brokerage account and do not return
  voting instructions, will my shares be voted?.............      3
Can I change my vote after I return my proxy?...............      3
How are votes counted?......................................      3
Who pays for this proxy solicitation?.......................      3
STOCK OWNERSHIP.............................................      4
Who are the Largest Owners of the Company's Stock?..........      4
How Much Stock do Certain Beneficial Owners, the Company's
  Directors and Executive Officers Own?.....................      4
PROPOSAL NO. 1 -- ELECTION OF BOARD OF DIRECTORS............      7
Nominees for Director.......................................      7
Business Experience of Nominees for Director................      8
Business Experience of Current Non-Nominee Directors........
Directors' Compensation.....................................      9
Information Concerning Board and Committee Meetings and
  Committees of the Board...................................     11
Recent Corporate Governance Initiatives.....................     12
Information Concerning Executive Officers...................     16
Employment Agreements.......................................     18
Report of the Compensation Committee........................     22
Compensation Committee Interlocks and Insider
  Participation.............................................     23
Summary Compensation Table..................................     24
Option Grants in Fiscal 2002................................     26
Option Exercises and Values for Fiscal 2002.................     27
Common Stock Price Performance..............................     29
Certain Relationships and Related Transactions..............     30
Section 16(a) Beneficial Ownership Reporting Compliance.....     31
Report of the Audit Committee...............................     32
Fees Paid to KPMG LLP.......................................     33
PROPOSAL NO. 2 -- APPROVAL OF AN AMENDMENT TO THE IMCLONE
  SYSTEMS INCORPORATED 2002 STOCK OPTION PLAN...............     35
PROPOSAL NO. 3 -- APPROVAL OF IMCLONE SYSTEMS INCORPORATED
  ANNUAL INCENTIVE PLAN.....................................     39
</Table>

                                       (i)

<Table>
                                                             
PROPOSAL NO. 4 -- RATIFICATION OF INDEPENDENT CERTIFIED
  PUBLIC ACCOUNTANTS........................................     42
Stockholder Proposals.......................................     42
Other Matters...............................................     42
Appendix A -- ImClone Systems Incorporated Audit Committee
  Charter...................................................    A-1
Appendix B -- ImClone Systems Incorporated 2002 Stock Option
  Plan......................................................    B-1
Appendix C -- ImClone Systems Incorporated Annual Incentive
  Plan......................................................    C-1
</Table>

                                       (ii)


                          IMCLONE SYSTEMS INCORPORATED
                               180 VARICK STREET
                            NEW YORK, NEW YORK 10014

                                PROXY STATEMENT

     This proxy statement is furnished in connection with the solicitation of
proxies for use at the Annual Meeting of Stockholders of ImClone Systems
Incorporated (the "Company") to be held at 10:00 a.m., local time, on Monday,
September 15, 2003, at ImClone Systems Incorporated, 33 Chubb Way, Somerville,
New Jersey 08876, and at any postponements or adjournments thereof. The Notice
of Annual Meeting, this proxy statement and the accompanying proxy card are
first being mailed to stockholders on or about August 25, 2003.

                               ABOUT THE MEETING

What is the purpose of the meeting?

     At the meeting, stockholders will act upon the matters outlined in the
accompanying notice of meeting, including the election of Directors, approval of
an amendment to the ImClone Systems Incorporated 2002 Stock Option Plan,
approval of the ImClone Systems Incorporated Annual Incentive Plan and
ratification of the appointment of the Company's independent auditors. In
addition, the Company's management will report on the performance of the Company
during fiscal 2002.

Who may attend the meeting?

     Although the Company encourages you to complete and return the proxy card
or to vote by telephone or via the Internet to ensure that your vote is counted,
you may attend the meeting and vote your shares in person. All stockholders as
of the record date, or their duly appointed proxies, may attend the meeting. If
you hold your shares in "street name" (that is, through a broker or other
nominee), you will need to bring a copy of a brokerage statement reflecting your
stock ownership as of the record date. In all cases, you must bring a form of
personal identification. To ensure the availability of adequate space for the
Company's stockholders wishing to attend the meeting, priority seating will be
given to stockholders of record, stockholders who hold their shares in street
name and invited guests of management. In addition, each stockholder may bring
one guest. In order that seating may be equitably allocated, a stockholder
wishing to bring more than one guest must write to the Secretary of the Company
in advance of the meeting and receive written concurrence.

Who is entitled to vote?

     Only stockholders of record at the close of business on the record date,
August 20, 2003, are entitled to receive notice of the meeting and to vote the
shares of common stock that they held on that date at the meeting or any
postponements or adjournments thereof. Each outstanding share entitles its
holder to cast one vote on each matter to be voted upon at the meeting.

     Pursuant to the Company's Stockholder Agreement, dated as of September 19,
2001, with Bristol-Myers Squibb Company ("BMS") and Bristol-Myers Squibb
Biologics Company (the "Stockholder Agreement"), during the period in which BMS
has the right to nominate at least one Director to the Company's Board of
Directors (a "BMS Director"), BMS and its affiliates are required to vote all of
their shares in the same proportion as the votes cast by all of the Company's
other stockholders with respect to the election or removal of non-BMS Directors.
BMS has the right to nominate at least one BMS Director if its ownership
interest in the Company is 5% or greater. BMS currently has the right to
nominate two Directors.

What constitutes a quorum?

     The presence at the meeting, in person or by proxy, of the holders of a
majority of the shares of common stock outstanding on the record date will
constitute a quorum, permitting business to be conducted at the

                                        1


meeting. As of the record date, the Company had 74,591,027 shares of common
stock outstanding. Proxies received but marked as abstentions and broker
non-votes will be included in the calculation of the number of shares considered
to be present at the meeting.

What vote is required to approve each item?

     Election of Directors.  The affirmative vote of a plurality of the votes
cast at the meeting is required for the election of Directors. This means that
the individuals who receive the highest number of votes will be elected as
Directors, up to the maximum number of Directors to be chosen at the meeting.

     Other Items.  For each other item, the affirmative vote of the holders of a
majority of the shares present in person or represented by proxy and entitled to
vote on the item will be required for approval.

What are the recommendations of the Board of Directors?

     The persons named as proxy holders on the proxy card will vote in
accordance with the recommendations of the Board of Directors (the "Board"). The
Board's recommendation is "FOR" each of the items set forth in this proxy
statement. With respect to any other matter that properly comes before the
meeting, the proxy holders will vote as recommended by the Board or, if no
recommendation is given, in their own discretion.

How do I vote?

     You may vote in the following ways:

          (a) In person:  You may vote in person at the meeting. If you hold
     your shares in street name, you must obtain a legal proxy, executed in your
     favor, from your broker or nominee if you wish to vote your shares at the
     meeting.

          (b) In writing:  If you complete and properly sign the accompanying
     proxy card and return it to the Company, it will be voted as you direct. If
     you sign and return your proxy card but do not give voting instructions,
     the proxy holders will vote your shares as recommended by the Board of
     Directors. If you are a record holder and attend the meeting, you may
     deliver your completed proxy card in person. If you hold your shares in
     street name, your broker or nominee has enclosed or provided a voting
     instruction form for you to use in directing the broker or nominee how to
     vote your shares.

          (c) By telephone:  Call the toll-free telephone number on your proxy
     card to vote by telephone. You must have a touch-tone telephone to use this
     option. You will need to follow the instructions on your proxy card and the
     voice prompts.

          (d) Via the Internet:  Go to the website listed on your proxy card to
     vote via the Internet. You will need to follow the instructions on your
     proxy card and on the website.

     Telephone and Internet voting options are available 24 hours a day, seven
days a week. When prompted, you will need to enter the control number shown on
your proxy card. You will then be able to vote your shares and confirm that your
instructions have been properly recorded. If you vote by telephone or via the
Internet, your electronic vote authorizes the named proxies in the same manner
as if you signed, dated and returned your proxy card. The telephone and Internet
voting procedures, including the use of control numbers found on the proxy
cards, are designed to authenticate stockholders' identities, to allow
stockholders to vote their shares of common stock and to confirm that their
instructions have been properly recorded. If you vote by telephone or via the
Internet, you do not need to return your proxy card. If you hold your shares in
street name, you may vote by telephone or via the Internet if your broker or
nominee makes these methods available, in which case the broker or nominee will
enclose the instructions with this proxy statement.

What if I am a beneficial owner rather than a holder of record?

     If your shares are held in a stock brokerage account or by a bank or other
nominee, you are considered to be the beneficial owner of shares held in street
name. These proxy materials are being forwarded to you by your broker or
nominee, who is considered to be the holder of record with respect to your
shares. As the
                                        2


beneficial owner, you have the right to direct your broker or nominee as to how
to vote by filling out the voting instruction form provided by your broker or
nominee. Telephone and Internet voting options may also be available to
beneficial owners. As a beneficial owner, you are also invited to attend the
meeting, but you must obtain a legal proxy from the holder of record of your
shares in order to vote in person at the meeting.

If I hold my shares in a brokerage account and do not return voting
instructions, will my shares be voted?

     If your shares are held in street name, your broker or nominee will ask you
how you want your shares to be voted. If you provide voting instructions, your
shares must be voted as you direct. If you do not furnish voting instructions,
one of two things can happen, depending upon whether a proposal is "routine."
Under the rules that govern brokers who have record ownership of shares
beneficially owned by their clients, brokers have discretion to cast votes on
routine matters, such as the election of Directors and ratification of the
appointment of independent auditors, without voting instructions from their
clients. Brokers are not permitted, however, to cast votes on "non-routine"
matters without such voting instructions. A "broker non-vote" occurs when a
broker holding shares for a beneficial owner does not vote on a particular
proposal because the broker does not have discretionary voting power for that
proposal and has not received voting instructions from the beneficial owner.

Can I change my vote after I return my proxy?

     Yes. Even after you have submitted your proxy, you may change your vote at
any time before the proxy is exercised by filing a notice of revocation or an
executed proxy card bearing a later date with the Secretary of the Company at
the Company's principal executive offices at 180 Varick Street, New York, New
York 10014. You may also change or revoke your proxy by telephone or via the
Internet at any time before the meeting in accordance with the instructions on
the enclosed proxy card. The powers of the proxy holders will be suspended if
you attend the meeting in person and so request, although attendance at the
meeting will not by itself revoke a previously granted proxy.

How are votes counted?

     For purposes of determining the presence of a quorum, abstentions and
broker non-votes will be counted by the Company as present at the meeting.
Abstentions and broker non-votes will not be voted either in favor of or against
any of the proposals. For the election of Directors, which requires a plurality
of the votes cast, votes withheld from one or more nominees will be excluded
entirely from the vote and will have no effect on the outcome. For each of the
other proposals, which will be decided by the affirmative vote of the holders of
a majority of the shares present in person or represented by proxy and entitled
to vote on such proposal, abstentions will be counted for purposes of
determining the number of votes cast on the proposal and will have the same
effect as negative votes, but broker non-votes will not be counted as entitled
to vote.

Who pays for this proxy solicitation?

     The Company does. In addition to sending you these materials, some of the
Company's employees may contact you by telephone, by mail, or in person. None of
these employees will receive any extra compensation for doing this. In addition,
the Company has retained Georgeson Shareholder Communications, Inc. to assist
the Company in soliciting your proxy for a fee of $6,000 plus reasonable
out-of-pocket expenses.

                                        3


                                STOCK OWNERSHIP

Who are the Largest Owners of the Company's Stock?

     Except as set forth in the table below, the Company knows of no single
person or group of related persons that is the beneficial owner of more than 5%
of the Company's common stock. This is based solely on Schedule 13G and Schedule
13D reports filed with the Securities and Exchange Commission (the "SEC") as of
April 15, 2003.

How Much Stock Do Certain Beneficial Owners, the Company's Directors and
Executive Officers Own?

     The following table shows the amount of the Company's common stock
beneficially owned (unless otherwise indicated) by persons or groups of related
persons that beneficially own greater than 5% of the Company's common stock, the
Company's current directors, the Company's named executive officers and the
Company's current directors and executive officers as a group. Except as
otherwise indicated, all ownership information is as of April 15, 2003.
"Beneficial Ownership" is a technical term defined by the SEC to mean more than
ownership in the usual sense. For example, you "beneficially own" the Company's
common stock if you own it directly or indirectly (e.g., through a relationship,
a position as a trustee or through an agreement) or if you have the right to
acquire it within 60 days (e.g., upon the exercise of options).

<Table>
<Caption>
                                                              AMOUNT AND NATURE
                                                                OF BENEFICIAL     PERCENT OF
NAME AND ADDRESS OF BENEFICIAL OWNER(1)                           OWNERSHIP        CLASS(2)
- ---------------------------------------                       -----------------   ----------
                                                                            
Bristol-Myers Squibb Company................................     14,392,003(3)      19.45%(4)
  345 Park Avenue
  New York, New York 10154
Capital Research and Management Company.....................      6,388,040(5)       8.62%(4)
  333 South Hope Street
  Los Angeles, CA 90071
FMR Group...................................................      4,775,560(6)       6.45%(4)
  82 Devonshire Street
  Boston, Massachusetts 02109
Harlan W. Waksal, M.D. .....................................      3,106,847(7)       4.19%
Samuel D. Waksal, Ph.D. ....................................      1,415,317(8)       1.91%
David M. Kies...............................................        447,508(9)          *
John Mendelsohn, M.D. ......................................        415,726(10)         *
Vincent T. DeVita, Jr., M.D. ...............................        279,055(11)         *
Paul B. Kopperl.............................................        261,056(12)         *
William R. Miller...........................................        201,471(13)         *
Daniel S. Lynch.............................................        196,667(14)         *
S. Joseph Tarnowski, Ph.D. .................................        182,364(15)         *
Arnold J. Levine............................................        161,145(16)         *
Andrew G. Bodnar, M.D., J.D.(17)............................         50,000(18)         *
Lily Waiyee Lee.............................................         43,808(19)         *
Clifford R. Saffron.........................................         35,000(20)         *
John A. Fazio...............................................          6,308(21)         *
All Current Directors and Executive Officers as a Group (21
  persons)..................................................      3,470,398(22)      4.69%
</Table>

- ---------------
  *  Less than 1%

 (1) Unless otherwise noted, each person's address is in care of ImClone Systems
     Incorporated, 180 Varick Street, Sixth Floor, New York, New York 10014.

 (2) The percentage of voting stock owned by each stockholder is calculated by
     dividing (1) the number of shares deemed to be beneficially held by such
     stockholder as of April 15, 2003, as determined in

                                        4


     accordance with Rule 13d-3 of the Securities Exchange Act of 1934, as
     amended (the "Exchange Act"), by (2) the sum of (A) 74,007,744, which is
     the number of shares of common stock outstanding as of June 15, 2003, plus
     (B) the number of shares of common stock issuable upon exercise of
     currently exercisable options and other derivative securities held by such
     stockholder. For purposes of this security ownership table, "currently
     exercisable options" consist of options exercisable as of April 15, 2003 or
     within 60 days after April 15, 2003. Except as indicated by footnote, the
     persons named in the table have sole voting and investment power with
     respect to all shares of common stock shown as beneficially owned by them.

 (3) This information is as of March 6, 2002 and was obtained from Amendment No.
     2 to Schedule 13D, filed with the SEC on March 6, 2002.

 (4) These percentages have been calculated based upon the number of shares
     reported as beneficially owned in the stockholder's latest Schedule 13G or
     Schedule 13D filing prior to April 15, 2003 and the number of shares
     outstanding as of June 15, 2003.

 (5) This information was obtained from a Schedule 13G filed with the Securities
     and Exchange Commission on February 10, 2003. It includes 363,040 shares of
     common stock resulting from the assumed conversion of the $20,000,000
     principal amount of ImClone Systems Incorporated 5 1/2% convertible notes
     due March 1, 2005.

 (6) This information was obtained from Amendment No. 4 to Schedule 13G, filed
     with the SEC on February 14, 2002. This number includes 4,766,438 shares
     beneficially owned by Fidelity Management & Research Company, a wholly
     owned subsidiary of FMR Corp. and a registered investment adviser, as a
     result of acting as an investment adviser to various registered investment
     companies. FMR Group is the parent company of various Fidelity funds and
     related parties. Edward C. Johnson 3d, Chairman of FMR Corp., and Abigail
     P. Johnson, a Director of FMR Corp., are also listed on the Schedule 13G as
     beneficial owners of the 4,775,560 shares.

 (7) Includes 333,334 shares issuable upon the exercise of currently exercisable
     options, 4,086 shares owned by Dr. Harlan W. Waksal's sons and 157 shares
     owned in a joint account with his wife.

 (8) Includes 1,250,000 shares issuable upon exercise of currently exercisable
     options. In an action brought by the Company on August 14, 2002 against Dr.
     Samuel D. Waksal in Supreme Court of the State of New York, New York
     County, the Company is seeking the cancellation of 833,333 of these
     options. See, "Employment and Separation Agreements". Dr. Samuel D. Waksal
     formerly served as the Company's President and Chief Executive Officer.

 (9) Includes 102,500 shares issuable upon the exercise of currently exercisable
     options; 30,000 shares held by a family foundation of which Mr. Kies is one
     of the trustees; 16,400 shares held as co-trustee for a trust for Mr. Kies'
     eldest minor son and 615 shares held by Mr. Kies' spouse as to which Mr.
     Kies disclaims beneficial ownership.

(10) Consists of 415,726 shares issuable upon the exercise of currently
     exercisable options.

(11) Includes 278,584 shares issuable upon the exercise of currently exercisable
     options.

(12) Includes 96,070 shares issuable upon the exercise of currently exercisable
     options; an aggregate of 139,486 shares held by trusts of which Mr. Kopperl
     is sole beneficiary and 500 shares held by Mr. Kopperl's spouse as to which
     Mr. Kopperl disclaims beneficial ownership.

(13) Includes 102,500 shares issuable upon exercise of currently exercisable
     options.

(14) Consists of 196,667 shares issuable upon exercise of currently exercisable
     options.

(15) Includes 173,176 shares issuable upon exercise of currently exercisable
     options.

(16) Includes 131,474 shares issuable upon exercise of currently exercisable
     options.

(17) Address is in care of Bristol-Myers Squibb Company, 345 Park Avenue, New
     York, New York 10154.

(18) Consists of 50,000 shares issuable upon exercise of currently exercisable
     options.

(19) Includes 42,000 shares issuable upon exercise of currently exercisable
     options.

(20) Includes 32,500 shares issuable upon exercise of currently exercisable
     options.

                                        5


(21) Consists of 6,308 shares issuable upon exercise of currently exercisable
     options.

(22) Includes an aggregate of (i) 2,729,309 shares issuable upon the exercise of
     currently exercisable options and (ii) 1,115 shares as to which beneficial
     ownership is disclaimed. Dr. Samuel D. Waksal and Dr. Harlan W. Waksal are
     no longer directors or executive officers of the Company. Their respective
     beneficial ownership of ImClone Systems securities as of April 15, 2003 is
     listed in the chart above.

                                        6


                                 PROPOSAL NO. 1

                         ELECTION OF BOARD OF DIRECTORS

     An entire Board of Directors, consisting of five members, will be elected
at the meeting. The Directors elected will hold office until their successors
are elected, which normally would be expected to occur at the next annual
meeting. The Board is actively involved in an ongoing search for additional
candidates for director positions, and has engaged, for a customary fee, a
professional search firm to assist the Board in identifying qualified
candidates.

     Pursuant to the Stockholder Agreement described above, Bristol-Myers Squibb
Company ("BMS") received the right to nominate two Directors so long as its
ownership interest in the Company is 12.5% or greater. BMS continues to have an
ownership interest greater than 12.5% and to possess the right to nominate two
Directors. However, BMS has not yet nominated a replacement to fill the seat on
the Board of Directors vacated by Peter S. Ringrose, M.A., Ph.D., who retired in
2002 from his position of Chief Scientific Officer and President, Pharmaceutical
Research Institute at BMS, and also resigned from his Director position at the
Company. Therefore, the Company currently expects that BMS will nominate only
one Director for election at the meeting.

     Nominations.  At the meeting, the Board of Directors expects to nominate
the five persons named in this proxy statement as Directors. Although the
Company does not know of any reason why any of these nominees might not be able
to serve, the Board may propose a substitute nominee if any nominee is not
available for election.

     General Information About the Nominees.  All of the nominees are currently
Directors of the Company. Each of the nominees has agreed to be named in the
proxy statement and to serve as a Director if elected.

NOMINEES FOR DIRECTOR

<Table>
<Caption>
                     NAME                       CURRENT POSITION WITH COMPANY   DIRECTOR OF COMPANY SINCE
                     ----                       -----------------------------   -------------------------
                                                                          
Andrew G. Bodnar, M.D., J.D.(5)(6)............        Director                            2001
Vincent T. DeVita, Jr., M.D.(4)(5)(6).........        Director                            1992
John A. Fazio(1)(6)...........................        Director                            2003
David M. Kies(2)(3)(5)(6).....................        Lead Director                       1996
William R. Miller(1)(2)(3)(5)(6)..............        Director                            1996
</Table>

- ---------------
(1) Member of Audit Committee

(2) Member of Compensation and Stock Option Committee

(3) Member of Nominating and Corporate Governance Committee

(4) Member of Research Oversight Committee

(5) Member of Special Committee

(6) Member of the Chief Executive Officer Search Committee

                                        7


                  BUSINESS EXPERIENCE OF NOMINEES FOR DIRECTOR

     ANDREW G. BODNAR, M.D., J.D., 55, has been a Director of the Company since
November 2001. Dr. Bodnar was designated and is being nominated as a Director
pursuant to a Stockholder Agreement, dated as of September 19, 2001, among the
Company, Bristol-Myers Squibb Company and Bristol-Myers Squibb Biologics
Company. Dr. Bodnar is Senior Vice President, Strategy and Medical & External
Affairs of Bristol-Myers Squibb Company. Previously, Dr. Bodnar served as
President, Oncology/Immunology and Worldwide Strategic Business Development for
Bristol-Myers Squibb's Pharmaceutical Group. Prior to joining Bristol-Myers
Squibb, Dr. Bodnar was Associate Chief of Internal Medicine, Acting Chief of
Cardiology and Director of the Internal Medicine Residency Program at
Massachusetts General Hospital in Boston. Dr. Bodnar serves on the Board of
Trustees of The New York Blood Center, The Fox Chase Cancer Center and The
American Boychoir School.

     VINCENT T. DEVITA, JR., M.D., 68, has been a Director of the Company since
February 1992. Since 1993, Dr. DeVita has served as Director of the Yale Cancer
Center as well as Professor of Medicine and Professor of Epidemiology and Public
Health at Yale University School of Medicine, New Haven, Connecticut. From
September 1988 through June 1995, Dr. DeVita served as Attending Physician at
Memorial Sloan-Kettering Cancer Center ("Sloan Kettering"), New York, and
through June 1991 as Physician-in-Chief. From 1980 to 1988, he served under
Presidential appointment as Director of the National Cancer Institute ("NCI"),
where he had held various positions since 1966. During his years with the NCI,
Dr. DeVita was instrumental in developing the first successful combination
cancer chemotherapy program. This work ultimately led to effective regimens of
curative chemotherapy for a variety of cancers. Dr. DeVita's numerous awards
include the 1990 Armand Hammer Cancer Prize and the 1982 Albert and Mary Lasker
Medical Research Award for his contribution to the cure of Hodgkin's disease.
Dr. DeVita received his M.D. from the George Washington University School of
Medicine, Washington, D.C. in 1961.

     JOHN A. FAZIO, 59, has served as a Director of the Company since February
2003. Mr. Fazio is a Certified Public Accountant and Certified Management
Accountant and was with PricewaterhouseCoopers ("PwC") from 1966 to 2000. As a
Senior General Practice Partner, he served as the lead audit partner to a number
of PwC's key multinational and national clients. Mr. Fazio was also a National
Business Leader in PwC's pharmaceutical practice in which he was responsible for
developing and delivering services on business issues impacting the industry to
assist clients in creating value-adding opportunities. As the head of PwC's
Strategic Risk Services practice, he managed a group of senior specialists to
assist companies in identifying key risks within their businesses and to
establish controls to mitigate such risks. Mr. Fazio is a Director of Dendrite
International, Inc. Also active in several professional organizations, he was
Chairman of the Accounting and Auditing Standards Committee of the New Jersey
Society of Certified Public Accountants, the State Society's senior technical
committee. Mr. Fazio earned his Bachelor of Science in Accounting from Penn
State University in 1965 and a Masters Degree in Accounting from Ohio State
University in 1967.

     DAVID M. KIES, 59, has been a Director of the Company since June 1996. Mr.
Kies is a Partner of the New York-based law firm Sullivan & Cromwell,
specializing in mergers and acquisitions, securities and general corporate
matters.

     WILLIAM R. MILLER, 75, has been a Director of the Company since June 1996.
Mr. Miller served as Vice Chairman of the Board of Directors of the
Bristol-Myers Squibb Company from 1985 until 1991, at which time he retired. Mr.
Miller is a director of Transkaryotic Therapies, Inc. and Chairman of the Board
of Vion Pharmaceuticals, Inc. He is Chairman of the Board of Trustees of the
Cold Spring Harbor Laboratory and is a past Chairman of the Board of the
Pharmaceutical Manufacturers Association. Mr. Miller is a Trustee of the
Manhattan School of Music, a director of Opera Orchestra of New York and a
Managing Director of the Metropolitan Opera Association. He is a member of
Oxford University Chancellor's Court of Benefactors, Honorary Fellow of St.
Edmund Hall and Chairman of the English-Speaking Union of the United States.

     THE BOARD RECOMMENDS A VOTE "FOR" EACH OF THE NOMINEES NAMED ABOVE
(PROPOSAL NO. 1 ON YOUR PROXY CARD).

                                        8


                            DIRECTORS' COMPENSATION

CASH COMPENSATION

     Exclusive of the Chairman of the Board, each non-employee Director of the
Company received compensation of $30,000 for 2002 services as a Director, or a
pro rated portion thereof for persons not serving the full fiscal year, as well
as reimbursement of the Director's reasonable out-of-pocket expenses incurred in
connection with his Board and Board committee activities. Exclusive of Directors
appointed as Chairman of the Board or Lead Director, each non-employee Director
of the Company will receive compensation of $30,000 for 2003 services as a
Director, or a pro rated portion thereof for persons not serving the full fiscal
year, as well as reimbursement of his reasonable out-of-pocket expenses incurred
in connection with his Board and Board committee activities.

     For 2002, the Chairman of the Board received $150,000 for his services as
Chairman as well as reimbursement of his reasonable out-of-pocket expenses
incurred in connection with his Board and Board committee activities. On January
24, 2003, the annual compensation for the Chairman of the Board was lowered to
$50,000 for 2003, or a pro rated portion thereof if not serving the full fiscal
year. Mr. Robert F. Goldhammer resigned as Chairman of the Board on April 29,
2003 and continued service as a Director until he resigned as a Director on July
17, 2003. Accordingly, Mr. Goldhammer's total compensation for 2003 was
$22,979.28. On May 14, 2003, the Board appointed a Lead Director and set
compensation for this position at a rate of $45,000 per year or a prorated
portion thereof for persons not serving the full fiscal year, as well as
reimbursement of his reasonable out-of-pocket expenses incurred in connection
with his Board and Board committee activities.

     In addition, the Chairman of each Board committee, exclusive of the
Chairman of the Board, will receive $10,000 in 2003, or a pro rated portion
thereof for persons not serving the full fiscal year, as compensation for
services as committee Chairman. For 2003, each Director, including the Chairman
of the Board and Lead Director, will receive an additional $1,000 per meeting
fee where such meeting is in addition to the Board's regularly scheduled
meetings for the year. For each Board committee meeting that such Director
attends, whenever such meeting is in addition to the Board committee's regularly
scheduled meetings for the year, such Director will receive an additional $400
per meeting.

DIRECTORS' STOCK OPTIONS

     Each Director who is not an employee of the Company was granted for 2002
options to purchase 30,000 shares of common stock, except that the Chairman of
the Board was granted for each of 2002 and 2003 options to purchase 60,000
shares of common stock. On January 24, 2003, the Chairman of the Board, Mr.
Goldhammer, was granted options to purchase 60,000 shares of common stock,
vesting as to 25% on each of April 24, 2003; July 24, 2003; October 24, 2003 and
January 24, 2004. In light of Mr. Goldhammer's resignation as Chairman of the
Board on April 29, 2003 and continued service as a Director until July 17, 2003
this option grant was amended to 37,912 shares of common stock, vesting as to
15,000 shares on April 24, 2003; 7,912 shares on July 24, 2003; 7,500 shares on
October 24, 2003 and 7,500 shares on January 24, 2004. Due to Mr. Goldhammer's
July 17, 2003 resignation from the Board, this option grant was again amended
solely to comprise 15,000 shares which vested on April 24, 2003. On May 14,
2003, the option grant for the position of Lead Director was set at 45,000
shares. As a result, the Company's Lead Director was granted an option to
purchase 10,467 shares of common stock, vesting as to 2,967 shares on July 24,
2003; 3,750 shares on October 24, 2003 and 3,750 shares on January 24, 2004,
representing the prorated portion of such additional share grant after
accounting for the Lead Director's previous option grant as a Director for 2003.

     Each individual newly joining the Board during the fiscal year receives a
pro rated portion of the options described above based on the portion of the
fiscal year served. Prior to January 2003, such options generally vested after
12 months of service on the Board from the date of grant, subject to such
individual's continued service on the Board on the scheduled date of vesting and
had an exercise price equal to the fair market value of the common stock on the
date of grant. Beginning in January 2003, such options vest quarterly, subject
to such individual's continued service on the Board on the scheduled date of
vesting and have an exercise price

                                        9


equal to the fair market value of the common stock on the date of grant. In
addition, each Director newly joining the Board who is not an employee of the
Company is made a one-time grant of options to purchase 50,000 shares of common
stock. Such options vest as to 25% of the shares of common stock over the
four-year period commencing with the date of grant, subject to such individual's
continued service on the Board on the scheduled date of vesting, and have an
exercise price equal to the fair market value of the common stock on the date of
grant. From time to time, Directors who are not employees of the Company may be
granted additional options in consideration for providing services on the Board.
No such additional grants were made during 2002. In 2003, options to purchase
5,000 shares of common stock having an exercise price equal to the fair market
value of the common stock on the date of grant, which fully vested on the date
of grant, were granted to each of Drs. DeVita, Levine and Mendelsohn and Messrs.
Goldhammer, Kies, Kopperl and Miller. The table below sets forth option grants
that were made during the year ended December 31, 2002 in consideration for such
Directors serving on the Board to Directors who are not employees of the
Company:

<Table>
<Caption>
                                                               NUMBER OF
NAME                                                            OPTIONS
- ----                                                          ------------
                                                           
Richard Barth...............................................  30,000(1)(3)
Andrew G. Bodnar............................................  30,000(1)
Vincent T. DeVita, Jr. .....................................  30,000(1)
John A. Fazio...............................................       0(2)
Robert F. Goldhammer........................................  60,000(1)
David M. Kies...............................................  30,000(1)
Paul B. Kopperl.............................................  30,000(1)
Arnold J. Levine............................................  30,000(1)
John Mendelsohn.............................................  30,000(1)
William R. Miller...........................................  30,000(1)
Peter S. Ringrose...........................................  30,000(1)(3)
</Table>

- ---------------
(1) These options were granted automatically, pursuant to the terms of the 1996
    Non-Qualified Stock Option Plan, on February 15, 2002 at a per share
    exercise price of $18.44, which is equal to the fair market value of the
    common stock on the date of grant. The options vested and became exercisable
    in their entirety on February 15, 2003 and will terminate on February 14,
    2012.

(2) Mr. Fazio joined the Board in 2003.

(3) Mr. Barth and Dr. Ringrose resigned from the Board in 2002 and therefore
    forfeited these options.

                                        10


                   INFORMATION CONCERNING BOARD AND COMMITTEE
                      MEETINGS AND COMMITTEES OF THE BOARD

     The Board of Directors oversees the business and affairs of the Company and
monitors the performance of management. In accordance with corporate governance
principles, the Board does not involve itself in day-to-day operations. During
the year ended December 31, 2002, there were fourteen meetings of the Company's
Board. The Board also took certain actions by unanimous written consent. Except
for Dr. Arnold J. Levine, no incumbent Director attended fewer than 75% of the
aggregate of the total number of meetings of the Board and the total number of
meetings held by all committees of the Board on which he served.

     The Company has an Audit Committee of the Board currently composed of Paul
B. Kopperl (Chairman), William R. Miller, Arnold J. Levine and John A. Fazio.
Each of the members of the Audit Committee is an "independent director" as
defined in Rule 4200 of the listing standards of the National Association of
Securities Dealers, Inc. (an "Independent Director"). John A. Fazio is an "Audit
Committee Financial Expert" as that term is defined by the rules of the
Securities Exchange Commission (the "SEC"). Mr. Kopperl is not standing for
re-election to the Board and it is expected that Mr. Fazio will assume the role
of Chairman of the Audit Committee. The Audit Committee operates under a written
charter. The written charter that was in effect through August 14, 2003 was
attached as Appendix A to the Company's proxy statement for its 2000 fiscal
year. The current written charter was adopted on August 14, 2003 and is attached
as Appendix A to this proxy statement and described below under "Corporate
Governance Initiatives". The Audit Committee met seven times during the year
ended December 31, 2002.

     The Company has a Compensation and Stock Option Committee (the
"Compensation Committee") of the Board currently composed of William R. Miller
(Chairman), David M. Kies and Paul B. Kopperl, all of whom are Independent
Directors. The Compensation Committee operates under a written charter described
below under "Corporate Governance Initiatives". The Compensation Committee met
four times during the year ended December 31, 2002, and also took certain
actions by unanimous written consent.

     The Company has a Nominating and Corporate Governance Committee currently
composed of David M. Kies (Chairman), Paul B. Kopperl, Arnold J. Levine and
William R. Miller, all of whom are Independent Directors. The Nominating and
Corporate Governance Committee operates under a written charter described below
under "Corporate Governance Initiatives". The Nominating and Corporate
Governance Committee met three times during the year ended December 31, 2002.
The Nominating and Corporate Governance Committee considers nominations for
Director made by stockholders of the Company in accordance with the procedures
for submission of proposals at annual or special meetings of stockholders set
forth in the Company's Amended and Restated By-laws. Such procedures require
that notice by any stockholder be delivered to the Secretary of the Company not
less than 60 nor more than 90 days prior to the date of the meeting, which
notice shall include a statement in writing setting forth the name of the person
to be nominated as Director, the number and class of all shares of each class of
stock of the Company beneficially owned by such person, the information
regarding such person required by paragraphs (a), (e) and (f) of Item 401 of
Regulation S-K adopted by the SEC (or the corresponding provisions of any
regulation subsequently adopted by the SEC applicable to the Company), such
person's signed consent to serve as a Director of the Company if elected, such
person's name and address and the number and class of all shares of each class
of stock of the Company beneficially owned by such person. In nominating
candidates for Director, the Nominating and Corporate Governance Committee
considers such factors as judgment, skill, diversity, experience in the
biotechnology/pharmaceutical industry, experience in medical research or
oncology, the prospective interplay of the candidate's experience with the
experience of other Board members, and the extent to which the candidate would
be a desirable addition to the Board and any committees of the Board. In
evaluating current Directors for re-nomination to the Board, the Nominating and
Corporate Governance Committee assesses the performance of each such Director,
as well as the challenges and needs of the Company. In response to recent proxy
rule amendments proposed, but not yet issued, by the SEC, the Company plans to
evaluate the need to issue additional guidance to stockholders on Nominating and
Corporate Governance Committee policies and procedures.

                                        11


     The Company has a Research Oversight Committee currently composed of
Vincent T. DeVita, Jr. (Chairman), Arnold J. Levine and John Mendelsohn. The
Research Oversight Committee met fourteen times during the year ended December
31, 2002.

     In February 2002, the Board of Directors established a Special Committee.
The Special Committee is currently composed of Andrew G. Bodnar, Vincent T.
DeVita, Jr., David M. Kies, Paul B. Kopperl, Arnold J. Levine, John Mendelsohn
and William R. Miller. The Special Committee has been delegated all lawful
authority of the Board in connection with the investigation by the SEC into
possible violations of the federal securities laws by the Company and certain
unnamed individuals, the subpoena from a grand jury sitting in the United States
District Court for the Southern District of New York related to an investigation
by the United States Department of Justice, the inquiry of the Oversight and
Investigations Subcommittee of the House Energy and Commerce Committee into the
conduct of the Company in the development of the Company's product candidate,
ERBITUX(TM), federal securities actions naming the Company and certain Directors
as defendants, stockholder derivative actions, a proposal from BMS on February
5, 2002 which sought to restructure the relationship between the Company and BMS
(which has subsequently been resolved through the amendment of the agreement
between the Company and BMS dated March 5, 2002), and any matters that may arise
in the future based upon the same or similar facts or allegations. The Special
Committee met twelve times during the year ended December 31, 2002.

                    RECENT CORPORATE GOVERNANCE INITIATIVES

     The Company has strengthened and will continue to strengthen the controls
and procedures and improve the Company's corporate governance in order to ensure
the accuracy and timeliness of its financial reporting, as well as the Company's
compliance with tax and other regulatory requirements. As part of this
commitment, the Company has initiated a number of steps, including those in
response to the Sarbanes-Oxley Act of 2002 and corresponding SEC and Nasdaq
requirements or proposals. Specific actions taken or planned by the Company
include the following:

     - The Company has adopted Corporate Governance Guidelines, a Code of
       Business Conduct and Ethics, and formal charters for all of its Board
       committees. In addition, all employees, officers, directors, consultants
       and Scientific Advisory Board members will be required to sign an
       acknowledgement on an annual basis that they have read the Code of
       Business Conduct and Ethics policy, understand its contents, and agree to
       abide by its terms as a condition of employment or association with the
       Company. The Company plans to post a copy of the Company's Corporate
       Governance Guidelines, Code of Business Conduct and Ethics, and Board
       committee charters on the Company's website, www.imclone.com, in the near
       future.

     - The Company has both strengthened the Audit Committee's Charter and
       appointed a new member to its Board of Directors and Audit Committee,
       John A. Fazio. Mr. Fazio is a former Senior General Practice Partner of
       PricewaterhouseCoopers, qualifies as a "Audit Committee Financial Expert"
       under the Sarbanes-Oxley Act, and brings considerable financial expertise
       in the pharmaceutical industry.

     - The Company has established a Disclosure Committee to formally organize
       and oversee the disclosure process. The Committee consists of finance,
       investor relations, intellectual property, internal audit and legal
       personnel, with a mandate to design and establish controls and other
       procedures to assist its senior officers in overseeing the accuracy and
       timeliness of the Company's disclosures.

     - The Company has created an Internal Audit function with a formal charter,
       which mandates that the department provide independent, objective and
       timely analyses and assurances to senior management and the Board of
       Directors as to the adequacy and effectiveness of the Company's risk
       management, control and governance processes.

     - The Company has conducted a comprehensive review of the adequacy of its
       policies and procedures with respect to the administration of its equity
       compensation plans (including stock option and warrant plans) and
       purchases and sales of the Company's securities. The Company revised its
       Insider Trading Policy and now requires that all employees, officers,
       directors, consultants and Scientific Advisory
                                        12


       Board members sign an acknowledgement that they have read the policy,
       understand its contents and agree to abide by its terms as a condition of
       employment or association with the Company. In addition, the Company has
       significantly increased the number of senior managers designated as
       executive officers obligated to file reports under Section 16(a) of the
       Exchange Act. In addition, the Company has conducted an internal review
       of its tax withholding and reporting policies and established procedures
       to ensure that the Company is in compliance with federal, state and local
       tax codes and regulations.

     - The Company is taking steps to ensure that it is in compliance with the
       requirements of Section 404 of the Sarbanes-Oxley Act. The Company
       intends to modify and enhance its internal control structure consistent
       with the broad guidelines issued by the Committee of Sponsoring
       Organizations of the Treadway Commission ("COSO"). The COSO Integrated
       Framework -- Internal Controls report provides a sound basis for
       establishing internal control systems and determining their
       effectiveness. It is generally regarded as providing the most
       recognizable and suitable set of control criteria against which internal
       controls and procedures for financial reporting may be judged, and it
       meets the test of an authoritative framework that is widely accepted. The
       SEC's rules for Section 404 refer to the COSO framework and U.S.
       professional auditing literature embraces COSO. For this purpose, the
       Company will engage the assistance of a professional services firm that,
       in addition to providing expert advice and guidance, will ensure that an
       objective assessment is performed.

     - The Company has established the position of Chief Tax Officer, a new
       position charged with the responsibility of supervising the Company's
       policies and procedures with respect to federal, state, local and foreign
       tax administration and compliance, including, but not limited to,
       compliance with tax withholding requirements.

  Corporate Governance Guidelines

     The Company's Corporate Governance Guidelines (the "Guidelines") were
adopted on November 20, 2002 in order to promote the functioning of the
Company's Board and its committees. The Guidelines set forth certain goals
relating to the composition of the Board. The Guidelines also establish the
procedures and criteria for the selection of Directors, a majority of which must
consist of "independent directors" under proposed requirements set forth in
recently proposed amendments to the rules of the Nasdaq Stock Market, Inc.
("Nasdaq"). The Guidelines specify the frequency of Board meetings and executive
sessions for independent directors. The Guidelines provide that the Board shall
have, at a minimum, all the committees required by Nasdaq. Currently, the
committees of the Board are: the Audit Committee, the Compensation and Stock
Option Committee, the Nominating and Corporate Governance Committee, the
Research Oversight Committee, the Special Committee and the Chief Executive
Officer Search Committee. The Guidelines also set forth the principles for
compensation of the Chief Executive Officer of the Company, executives of the
Company and the Board, as well as certain expectations regarding the performance
of Directors' duties, including commitment to the Company and attendance at
Board meetings, duty of loyalty to the Company, and confidentiality.

  Code of Business Conduct and Ethics

     The Code of Business Conduct and Ethics (the "Code"), adopted by the
Company's Board on November 20, 2002, sets forth the key guiding principles that
represent Company policies and establish conditions for employment at or
association with the Company. These principles include:

     - conducting the Company's business affairs with integrity and honesty and
       in full compliance with all applicable laws, rules and regulations;

     - a prohibition against trading on inside information;

     - the protection of confidential proprietary information belonging to the
       Company;

     - avoiding potential or actual conflicts of interests;

                                        13


     - the protection and proper use of Company assets;

     - a prohibition against misuse of corporate property, information or
       position;

     - fair dealing practices;

     - full, fair, accurate, timely and understandable disclosure to security
       holders about the Company's financial condition and results of
       operations;

     - compliance with the Code and all applicable laws, rules and regulations,
       and reporting of illegal or unethical behavior;

     - equal opportunity, non-discrimination and fair employment policies;

     - rules regarding political contributions and activities; and

     - compliance with all applicable environmental and workplace health and
       safety laws and regulations.

     In addition, the Code establishes procedures for employees, officers,
directors, consultants and Scientific Advisory Board members associated with the
Company to follow in situations which may conflict with the Code's ethical
principles.

  Audit Committee Charter

     On August 14, 2003, the Company adopted its Audit Committee Charter, which
provides that the Audit Committee shall be comprised of at least three
Directors, each of whom shall be an "independent director" as defined in Rule
4200 (a)(14) of the listing standards of the National Association of Securities
Dealers, Inc., as required by the Sarbanes-Oxley Act of 2002. All of the members
of the Audit Committee must be able to read and understand fundamental financial
statements, including the Company's balance sheet, income statement and cash
flow statement, and at least one of the members shall qualify as an "Audit
Committee Financial Expert" as that term is defined by the Sarbanes-Oxley Act of
2002.

     The Audit Committee is an oversight body primarily concerned with
overseeing the accounting and financial reporting processes of the Company and
audits of the Company's financial statements. Accordingly, the Audit Committee
assists the Board with oversight of (i) the integrity of the Company's financial
statements, (ii) the Company's procedures and processes for compliance with
legal and regulatory requirements, (iii) the independent auditors'
qualifications and independence, and (iv) the performance of the independent
auditors and the Company's internal audit function. Furthermore, the Audit
Committee is responsible for the preparation of its report to be included in the
Company's annual proxy statement.

     The Audit Committee's responsibilities include, among others, (i) to
appoint, retain, oversee and terminate the independent auditors, including sole
authority to approve all audit engagement fees and terms, (ii) to pre-approve
all audit and non-audit services to be provided by the independent auditors,
(iii) to meet with management, the independent auditors and, if appropriate, the
head of the internal auditing department to discuss, among other things, the
scope of the annual audit, the annual audited financial statements and quarterly
financial statements, any significant matters arising from any audit, and any
major issues regarding accounting principles and financial statement
presentations, (iv) to review and evaluate the qualifications, performance and
independence of the independent auditors, including their responsibilities,
rotation, scope of audit and results of audit, (v) to review all related party
transactions of the Company, and (vi) to establish procedures for the receipt,
retention and treatment of complaints or suggestions received by the Company
regarding accounting, internal accounting controls or auditing matters and for
the confidential, anonymous submission by employees of the Company of concerns
regarding questionable accounting or auditing matters.

     The Audit Committee Charter provides the Audit Committee with the resources
and authority appropriate to discharge its duties and responsibilities,
including the authority to select, retain, terminate, and approve the fees and
other retention terms of special or independent counsel, accountants or other
experts and advisors, as it deems necessary or appropriate. The Audit Committee
Charter also establishes certain governance procedures relating to the
nomination of Directors to the Audit Committee, the frequency of Audit Committee
meetings and reporting by the Audit Committee to the Board. This summary of the
Audit

                                        14


Committee Charter is qualified in its entirety by reference to the full text of
such Charter attached as Appendix A to this proxy statement.

  Compensation and Stock Option Committee Charter

     On November 20, 2002, the Company adopted its Compensation and Stock Option
Committee Charter which provides that the Compensation and Stock Option
Committee (the "Compensation Committee") shall be comprised of at least three
Directors, each of whom shall be (i) independent under Nasdaq rules, (ii) Non-
Employee Directors for purposes of Section 16 of the Exchange Act ("Section
16"), and (iii) Outside Directors for purposes of Section 162(m) of the Internal
Revenue Code.

     The Compensation Committee has the responsibility to (i) oversee the
Company's compensation and benefits policies generally, (ii) evaluate
performance and set compensation for executive officers obligated to make
reports under Section 16(a) of the Exchange Act, and (iii) prepare the report on
executive compensation required to be included in the Company's annual proxy
statement. In connection with these responsibilities, the Compensation Committee
has the power to determine the Company's compensation and benefits (subject, if
applicable, to shareholder ratification), including reviewing and approving any
incentive compensation plans and equity-based plans of the Company. In addition,
the Compensation Committee recommends Director compensation to the Board for its
approval.

     The Compensation and Stock Option Committee Charter provides the
Compensation Committee with the sole authority to retain and terminate any
compensation consultant assisting it, including sole authority to approve all
such compensation consultant's fees and other retention terms. The Compensation
and Stock Option Committee Charter also establishes certain governance
procedures relating to the nomination of Directors to the Compensation
Committee, the frequency of Compensation Committee meetings and reporting by the
Compensation Committee to the Board.

  Nominating and Corporate Governance Committee Charter

     On November 20, 2002, the Company adopted its Nominating and Corporate
Governance Committee Charter, which provides that the Nominating and Corporate
Governance Committee (the "Nominating Committee") shall be comprised of at least
three Directors, each of whom shall be independent under Nasdaq rules. The
Nominating Committee has the responsibility to (i) identify and recommend
individuals for nomination as Directors, (ii) evaluate Board performance, and
(iii) develop and recommend to the Board Corporate Governance Guidelines and a
Code of Business Conduct and Ethics of the Company.

     The Nominating and Corporate Governance Committee Charter provides the
Nominating Committee with the resources and authority appropriate to discharge
its duties and responsibilities, including the authority to select, retain,
terminate, and approve the fees and other retention terms of special counsel or
other experts and consultants, as it deems necessary or appropriate. The
Nominating and Corporate Governance Committee Charter also establishes certain
governance procedures relating to the nomination of Directors to the Nominating
Committee, the frequency of Nominating Committee meetings and reporting by the
Nominating Committee to the Board.

  Research Oversight Committee Charter

     On November 20, 2002, the Company adopted its Research Oversight Committee
Charter, which provides that the Research Oversight Committee (the "Research
Committee") shall be comprised of at least three Directors. The Research
Committee has the responsibility to assist in the evaluation and oversight of
the Company's basic scientific research, including (i) periodic reviews of the
Company's research focus and efforts, (ii) review of priorities and research
project timelines, (iii) assessment of research resource allocation, and (iv)
reporting to the Board on the effectiveness of the Company's research efforts.

     The Research Oversight Committee Charter also establishes certain
governance procedures relating to the nomination of Directors to the Research
Committee, the frequency of Research Committee meetings and reporting by the
Research Committee to the Board.

                                        15


                             EXECUTIVE COMPENSATION

                   INFORMATION CONCERNING EXECUTIVE OFFICERS

     DANIEL S. LYNCH, 45, joined the Company in April 2001 as its Vice
President, Finance and Chief Financial Officer. In September 2001, he was
promoted to Senior Vice President, Finance and Chief Financial Officer and in
February 2002 was appointed Secretary of the Company. In April 2003, he became
Acting Chief Executive Officer and was appointed Senior Vice President and Chief
Administrative Officer. From May 1999 through March 2001, he served as Chief
Financial Officer of Derby Cycle Corporation. Prior to this, Mr. Lynch served
for 15 years in various capacities at Bristol-Myers Squibb Company, including
from December 1998 through May 1999, as its Vice President, Finance, U.S.
Pharmaceutical, Worldwide Medicines Group; from April 1998 through November 1998
as its Vice President, Finance, Technical Operations, Worldwide Medicines Group;
from July 1997 through March 1998 as its Vice President, Finance,
Intercontinental, Worldwide Medicines Group; and from February 1995 through June
1997 as its Vice President, Finance, Worldwide Consumer Medicines Group.

     PETER BOHLEN, PH.D., 60, has been Senior Vice President, Research of the
Company since January 2001. He joined the Company as Vice President, Research in
September 1996 and served in that capacity through December 2000. Prior to
joining ImClone, Dr. Bohlen has held managerial positions in drug discovery with
pharmaceutical and biotechnology concerns, and he has spent 15 years in various
academic positions. Dr. Bohlen received his doctoral degree in chemistry from
the University of Berne, Switzerland. His scientific work has focused on the
function of growth factors that regulate the formation of new blood vessels in
tumors.

     CLIFFORD R. SAFFRON, 45, has served as the Company's Senior Vice President
and General Counsel since January 2003. He joined the Company on February 1,
2002, as Vice President, Legal and Special General Counsel. From February 1,
1994 through November 30, 2001, he was Senior Vice President -- Deputy General
Counsel of ICN Pharmaceuticals, Inc. Prior to this, from October 1989 through
January 1994, he was a litigation associate with the law firm of Proskauer Rose
LLP in its New York City office.

     S. JOSEPH TARNOWSKI, PH.D., 49, has served as the Company's Senior Vice
President, Manufacturing Operations and Product Development since April 2001. He
was Vice President, Product and Process Development from January 1999 through
April 2001. Prior to joining the Company, he held various positions with
CellPro, Inc., the principal business of which was the development, manufacture
and marketing of automated systems that utilize monoclonal antibodies to purify
large quantities of specific cells for therapeutic and diagnostic applications.
He joined CellPro in June 1992 as Vice President of Operations, was appointed to
Vice President of Research and Development in June 1995 and became Senior Vice
President and Chief Technical Officer in December 1996. From November 1986 to
May 1992, Dr. Tarnowski was Director, Process and Product Development of Scios
Nova Inc. (formerly California Biotechnology Inc.), a company that develops
recombinant human proteins for therapeutic uses. Dr. Tarnowski received a Ph.D.
in Biochemistry from the University of Tennessee in 1979 and was a Postdoctoral
Fellow at the Roche Institute of Molecular Biology from 1979 through 1981.

     MICHAEL P. BAILEY, 38, has served as the Company's Vice President,
Marketing since January 2003. Mr. Bailey joined the Company in 1999 as Director
of Marketing and has served as a key member of the commercial team overseeing
both the product management and strategic planning groups. Prior to joining the
Company, Mr. Bailey served at Genentech, Inc. from 1997 through 1999 where he
managed the company's Cardiovascular Development Portfolio as Group Manager
Product Manager. From 1992 through 1997, Mr. Bailey served as one of two MBA
graduates selected for Smith-Kline Beecham's Executive Marketing Program. Within
the program, Mr. Bailey held a variety of commercial roles, including sales
(hospital and retail), strategic planning (new product marketing and managed
care), and product management. Mr. Bailey holds an MBA in International
Marketing from the University of Notre Dame.

     PETER R. BORZILLERI, 47, joined the Company in September 2002, as Vice
President, Internal Audit. Prior to joining the Company, Mr. Borzilleri held
financial and administrative management positions with various international
companies. Most recently, he was Vice President, Assistant Corporate Controller
for Automatic Data Processing, Inc., one of the world's largest providers of
computerized transaction processing, data

                                        16


communication and information services. From 1999 to 2001, he was Vice
President, Corporate Controller for United Rentals, Inc., the largest equipment
rental company in North America. From 1994 to 1999 he was Vice President, Group
Controller for Mannesmann Corp., the U.S. operations of a German industrial
company. Prior to that, he spent nine years with the Volvo North America Group,
with most of his time as the top financial and administrative executive of their
U.S. marine and industrial engine business, Volvo Penta North America. He
started his career in public accounting with the firm Deloitte & Touche, where
he spent seven years in their audit group. Mr. Borzilleri is a Certified Public
Accountant.

     MARGARET DALESANDRO, PH.D., 56, joined the Company in September 2002 as
Vice President, Project Management. She has responsibility for both Project and
Alliance Management functions within the Company. From February 2000 to
September 2002, Dr. Dalesandro was Senior Director of Project and Portfolio
Management at GlaxoSmithKline plc where she led global multi-disciplinary
project teams in the development and delivery of market-aligned Cardiovascular
and Urology therapies. From October 1998 through January 2000, Dr. Dalesandro
led the Technology Assessment practice in the U.S. for Cambridge Pharma
Consultancy. She consulted with major pharmaceutical and biotechnology companies
to develop business strategies based on evaluation of commercial opportunities
and risk in new product development. From September 1989 through September 1998,
Dr. Dalesandro held various positions in R&D at Centocor, Inc., including
director of the departments of Emerging Technologies and Immunobiology. She also
established the department of Cardiovascular Research within Centocor
Diagnostics. Dr. Dalesandro received both M.A. and Ph.D. degrees in Biochemistry
from Bryn Mawr College. She was an NIH Postdoctoral Fellow in Molecular
Immunology at Bowman Gray School of Medicine, Winston-Salem, NC.

     CHARLES DUNNE, 39, has been Vice President, Management Information Systems
and Facilities since January 2001. Mr. Dunne, one of the Company's first
employees, joined the Company in 1984 and has served it in a number of
capacities, including Assistant Vice President, Management Information Systems
and Facilities during 2000, Senior Director, Management Information Systems
during 1999 and Director, Management Information Systems during 1998. Mr. Dunne
supervised the construction of the Company's corporate headquarters and research
laboratories and has implemented all systems at the Company since 1984.

     PAUL A. GOLDSTEIN, 38, has been Vice President, Financial Operations since
January 2001. He joined the Company in January 1992 and has served in various
capacities since that date, including Assistant Vice President, Finance during
2000, Senior Director, Finance and Controller from January 1998 through December
1999 and Controller from January 1995 through December 1997. Prior to joining
the Company, he was employed by Laventhol & Horwath, a certified public
accounting firm in New York City. Mr. Goldstein is a certified public
accountant.

     MICHAEL J. HOWERTON, 51, has served as the Company's Vice President,
Finance and Business Development, and as its Acting Chief Financial Officer and
Secretary since May 2003. From August 2001 until May 2003, Mr. Howerton served
as the Company's Vice President, Business Development and was responsible for
the pursuit and development of new business opportunities for the Company,
including acquisitions, product in-licensing and out-licensing and strategic
alliances. Prior to joining the Company, Mr. Howerton built a 25-year career at
Bristol-Myers Squibb Company. In his most recent position at Bristol-Myers
Squibb, Mr. Howerton served as Vice President, Financial Analysis and Assistant
Controller from 1998 to 2001, directing activities relating to the financial and
strategic analysis, budgeting and profit planning of the Company. Prior to this
position, Mr. Howerton served as Vice President, Corporate Development for eight
years, and was responsible for activities relating to the acquisitions,
divestitures and strategic alliances for the Company's Worldwide Medicines
Group.

     LILY WAIYEE LEE, PH.D., 47, joined the Company in April 2001 as its Vice
President, Regulatory Affairs and Biostatistics. Dr. Lee was employed at The
Lipsome Company, Division of Elan Corporation, as its Vice President, Clinical &
Regulatory Operations and Biostatistics from 1995 to April 2001 and as its
Executive Director, Biostatistics and Data Management from 1993 through 1994.
Prior to that time she was employed for over eight years in various statistical
positions at Ciba Consumer Pharmaceuticals, Division of Ciba Geigy and at
Janssen Pharmaceutical, a division of Johnson & Johnson. Dr. Lee earned a
bachelor degree in

                                        17


statistics from the University of Minnesota and both a masters' degree in
Biostatistics and Ph.D. in Demography from the University of California,
Berkeley.

     RONALD A. MARTELL, 41, has served as the Company's Vice President,
Marketing and Sales since November 1998. Prior to joining the Company he worked
at Genentech, Inc. for ten years where he held various positions. Most recently,
from 1996 until joining the Company, he served as Genentech's Group Manager of
Oncology Products where he directed the launch of Herceptin, Genentech's
monoclonal antibody product approved to treat breast cancer. From 1995 to 1996,
he served as Senior Product Manager where he launched Pulmozyme for cystic
fibrosis in Europe. From 1994 through 1995, he served as Manager of Genentech's
Piedmont Sales Division. Prior to that, he served from 1993 as Associate Product
Manager for Genentech's Pulmozyme.

     MICHAEL NEEDLE, M.D., 43, has served as the Company's Vice President,
Clinical Affairs since January 2001. He joined the Company in April 2000 as its
Assistant Vice President, Clinical Affairs. Prior to joining the Company, Dr.
Needle served as Director, Oncology Clinical Research of G.D. Searle, a Monsanto
Company. From July 1993 through November 1997 Dr. Needle served as Assistant
Professor of Pediatrics and Neurology, Children's Hospital of Philadelphia,
University of Pennsylvania School of Medicine. Dr. Needle received a Bachelor of
Arts degree in Physics from Binghamton University and a Doctor of Medicine
degree from the State University of New York, Health Science Center at Brooklyn.
Dr. Needle performed his residency in Pediatrics at Kings County Hospital in
Brooklyn and his Pediatric Hematology/ Oncology fellowship at the Fred
Hutchinson Cancer Research Center in Seattle and the University of Texas, M.D.
Anderson Cancer Center in Houston.

     ANDREA F. RABNEY, 36, has served as the Company's Vice President, Corporate
Communications since January 2001. She joined the Company in 1993 as its
Director, Corporate Development and Investor Relations and has served in several
other managerial positions since that time, including Senior Director, Corporate
Development & Investor Relations from 1998 to 1999 and Assistant Vice President,
Corporate Communications during 2000. Prior to joining the Company, Ms. Rabney
served as a compliance analyst at Smith Barney Shearson Inc. (now Salomon Smith
Barney) where she was responsible for defining capital markets guidelines and
procedures for foreign and institutional accounts and trading desks. Ms. Rabney
holds a law degree from the Jacob D. Fuchsberg Law Center of Touro College.

     ERIK D. RAMANATHAN, 32, has served as the Company's Vice President, Legal
and Associate General Counsel since January 2003. He joined the Company in July
2000 as its Director, Legal and was promoted to Senior Director, Legal in
January 2002 and to Assistant Vice President, Legal in August 2002. From
September 1996 until January 2002, he specialized in health care transactions as
an attorney at the New York law firm of Proskauer Rose LLP. Mr. Ramanathan holds
a law degree from Harvard Law School and an undergraduate science degree from
The Johns Hopkins University.

     DOUGLAS E. SWAN, 51, joined the Company in July 2003 as its Vice President,
Sales. Prior to his employment with ImClone Systems, from 1999 through 2003, he
served as Vice President, North America for Oncology and Vice President, Global
Marketing for the Biosciences Division with Baxter Healthcare Corporation,
headquartered in Deerfield, IL. From 1996 to 1999, he served as Director of
Marketing for Genentech, Inc. where he led the market preparation and subsequent
launches of two monoclonal antibodies targeting lymphoma and breast cancer. Mr.
Swan began his pharmaceutical career with Bristol-Myers Squibb and held a
variety of Sales, Sales Management, Reimbursement and Marketing positions. He
holds a Bachelors of Science degree in Medical Biology from the University of
New England.

EMPLOYMENT AND SEPARATION AGREEMENTS

     EMPLOYMENT AGREEMENTS.  On September 19, 2001, Daniel S. Lynch, S. Joseph
Tarnowski, Harlan W. Waksal and Samuel D. Waksal entered into employment
agreements with the Company to be effective as of that date. The period of
employment, during which salary, bonus and benefits were to be provided to Mr.
Daniel S. Lynch, Dr. S. Joseph Tarnowski, Dr. Harlan W. Waksal and Dr. Samuel D.
Waksal began on September 19, 2001 and were to end on the third anniversary
thereof; provided that, with respect to Dr. Harlan W. Waksal and Dr. Samuel D.
Waksal, the term was to automatically be extended for one additional day each
                                        18


day served, unless a notice not to extend is provided. The employment agreements
with Dr. Samuel D. Waksal and with Dr. Harlan W. Waksal are no longer in effect.

     As of February 1, 2002, Clifford R. Saffron entered into an employment
agreement with the Company, effective as of that date and for a term of one year
from that date, during which period salary, bonus and benefits were to be
provided to Mr. Saffron. This employment agreement was amended by letter
agreement dated April 18, 2002, which provided for promotion of Mr. Saffron and
a corresponding additional grant of options. This employment agreement is no
longer in effect.

     The terms and conditions of these employment and separation agreements are
discussed below.

     DANIEL S. LYNCH.  Pursuant to the employment agreement with Mr. Daniel S.
Lynch, he originally served as the Company's Senior Vice President and Chief
Financial Officer and currently serves as the Company's Senior Vice President,
Chief Administrative Officer and Acting Chief Executive Officer. Mr. Lynch's
base salary is required to be not less than $360,000 and he is eligible to
receive an annual bonus; provided, that, the annual bonus shall not be less than
$360,000.

     Mr. Lynch is entitled to participate in customary employee benefit plans
and programs sponsored by the Company. In addition, the Company will reimburse
Mr. Lynch for up to $15,000 annually for personal tax planning and financial
advice and will provide him with a term life insurance policy with a death
benefit of at least $5,000,000. On September 19, 2001, pursuant to the terms of
the employment agreement, Mr. Lynch was granted a ten year stock option to
acquire 200,000 shares of the Company's common stock at an exercise price per
share equal to $50.01, the fair market value at the time of the grant. The stock
options will vest as to 33 1/3% of the shares subject thereto on the first,
second and third anniversary of the date of grant provided that Mr. Lynch is
then employed by the Company.

     If Mr. Lynch's employment is terminated by the Company without "cause" or
by Mr. Lynch for "good reason," Mr. Lynch will be paid or provided, in addition
to accrued but unpaid compensation and benefits and pro-rata bonus, (a) a
lump-sum cash payment equal to three times the sum of his base salary and
highest bonus paid in the last three years (with highest bonus paid deemed to be
at least $500,000); (b) continuation of health and welfare benefits for three
years; (c) immediate vesting of all stock-based awards, including the stock
options discussed above and all outstanding options shall remain exercisable
until the expiration of their term regardless of any termination of employment
provisions therein contained; (d) lump sum payment equal to the present value of
the maximum contributions the Company could have made under all of its
retirement plans if he had continued to be employed by the Company for an
additional three years and (e) payment by the Company of all contributions or
payments for the year of termination under all insurance benefits or policies
for the benefit of Mr. Lynch of which he would become the owner.

     If any of the payments to be made to Mr. Lynch could result in the
imposition of an excise tax under Section 4999 of the Internal Revenue Code of
1986, as amended, the Company shall pay Mr. Lynch an additional amount to fully
gross him up for such taxes, unless, by reducing the amounts payable to him by
less than 10%, no amounts would be subject to the excise tax, in which case the
payments shall be so reduced.

     The employment agreement also contains confidentiality, non-competition and
non-solicitation provisions.

     For purposes of the employment agreement, the Company will have "cause" to
terminate Mr. Lynch upon (a) a final conviction or plea of guilty or no contest
to a felony involving moral turpitude or (b) willful misconduct that is
materially and demonstrably injurious economically to the Company. Among other
events, Mr. Lynch will have "good reason" to terminate his employment with the
Company (a) if there is any material and adverse change in his duties or
responsibilities, (b) if there is a reduction in his base salary, bonus
opportunity, or any material benefit, (c) for any reason during the thirty-day
period following the first anniversary of a change in control of the Company,
(d) if he is required to relocate, or (e) if there is a breach of any material
provision of the employment agreement by the Company . Since its execution, this
employment agreement has not been amended to reflect any of the changes in Mr.
Lynch's responsibilities or title.

                                        19


     S. JOSEPH TARNOWSKI.  Dr. Tarnowski's employment agreement is substantially
the same as the employment agreement with Mr. Daniel S. Lynch, except that: (a)
he serves as Senior Vice President, Manufacturing Operations and Product
Development; (b) his base salary is required to be not less than $225,000 and
his minimum guaranteed bonus is $100,000, (c) he is not being reimbursed for
annual tax planning or financial advice; (d) he was granted a term life
insurance policy with a death benefit of at least $2,000,000; and (e) he was not
granted any additional stock options, however, consistent with Mr. Lynch's
agreement, all existing stock-based awards will immediately vest if Dr.
Tarnowski's employment agreement is terminated by the Company without "cause" or
by Dr. Tarnowski for "good reason," and his bonus is deemed to be no less than
$100,000 for purposes of calculating the lump sum cash payment in such event. In
addition, among other events, Dr. Tarnowski will have "good reason" to terminate
his employment with the Company: (a) if there is any material and adverse change
in his duties or responsibilities, (b) if there is a reduction in his base
salary, bonus opportunity, or any material benefit, (c) if he is required to
relocate, or (d) if there is a breach of any material provision of the
employment agreement by the Company.

     CLIFFORD R. SAFFRON.  Pursuant to the employment agreement with Mr.
Saffron, he originally served as the Company's Vice President and Special
General Counsel and later served as the Company's Senior Vice President and
Special General Counsel. Mr. Saffron currently serves as the Company's Senior
Vice President and General Counsel, but his employment agreement expired on
February 1, 2003 after its one-year term.

     Under Mr. Saffron's employment agreement, Mr. Saffron's base salary was
$225,000 per year and he was eligible to receive an annual target bonus of
$100,000 upon attaining performance goals established by the Company. Mr.
Saffron was entitled to participate in customary employee benefit plans and
programs sponsored by the Company. Pursuant to the terms of the employment
agreement, Mr. Saffron was granted stock options to acquire 60,000 shares of the
Company's common stock at an exercise price per share equal to $18.44, the fair
market value at the time the grant was approved by the Board of Directors. The
stock options vested as to 25% of the shares on the date of grant and as to 25%
of the shares on the first anniversary of the date of grant. The remaining
options will vest as to 25% of the shares on each of the second and third
anniversaries of the date of grant. In addition, Mr. Saffron was paid a signing
bonus of $25,000 in March 2002 pursuant to the employment agreement.

     Mr. Saffron's employment agreement was amended by letter agreement dated
April 18, 2002, providing for Mr. Saffron's promotion to Senior Vice President
and Special General Counsel. Under the letter agreement, Mr. Saffron was also
granted additional options to acquire 10,000 shares of the Company's stock at an
exercise price per share equal to $21.54, the fair market value at the time the
grant was approved by the Board of Directors. These stock options vested as to
25% of the shares on the date of grant and will vest as to 25% of the shares on
each of the first, second and third anniversaries of the date of grant.

     HARLAN W. WAKSAL.  Pursuant to the employment agreement with Dr. Waksal,
which has now been terminated, he originally served as the Company's Executive
Vice President and Chief Operating Officer and Director, then as the Company's
President and Chief Executive Officer and Director and then as the Company's
Chief Scientific Officer and Director. Dr. Waksal's base salary was required to
be not less than $455,000 and he was eligible to receive an annual bonus;
provided, that, the annual bonus was not to be less than $1,000,000 minus his
base salary for the relevant year.

     Dr. Waksal was entitled to participate in customary employee benefit plans
and programs sponsored by the Company. In addition, the Company reimbursed Dr.
Waksal for up to $15,000 annually for personal tax planning and financial
advice. Dr. Waksal was also entitled to a term life insurance policy with a
death benefit of at least $5,000,000, but he did not pursue the issuance of such
a policy. On September 19, 2001, pursuant to the terms of the employment
agreement, Dr. Waksal was granted a ten year stock option to acquire 1,000,000
shares of the Company's common stock at an exercise price per share equal to
$50.01, the fair market value at the time of the grant. The stock options were
to vest as to 100% of the shares subject thereto on the third anniversary of the
date of grant; provided, that, 33 1/3% of the shares subject to the stock option
were to each automatically vest prior to the third anniversary if Dr. Waksal
remained employed by the Company when the Company's ten day average stock price
reaches $60, $80 and $100 per share, respectively. In addition, these

                                        20


stock options were to become 100% vested upon a "change in control" of the
Company. These options vested as to the first 33 1/3% on October 31, 2001.

     The term of Dr. Waksal's employment agreement was to automatically extend
beyond its three year initial term for one additional day each day served,
unless a notice by the Company not to extend was provided. If Dr. Waksal's
employment was terminated by the Company without "cause" or by Dr. Waksal for
"good reason," Dr. Waksal was to be paid or provided, in addition to accrued but
unpaid compensation and benefits and pro-rata bonus, (a) a lump-sum cash payment
equal to three times the sum of his base salary and highest bonus paid in last
three years (with highest bonus paid deemed to be at least two times his then-
current base salary); (b) continuation of health and welfare benefits for three
years; (c) immediate vesting of all stock-based awards, including the stock
options discussed above, and all outstanding options were to remain exercisable
until the expiration of their term regardless of any termination of employment
provisions therein contained; (d) lump sum payment equal to the present value of
the maximum contributions the Company could have made under all its retirement
plans if he had continued to be employed by the Company for an additional three
years and (e) payment by the Company of all contributions or payments for the
year of termination under all insurance benefits or policies for the benefit of
Dr. Waksal of which he would become the owner.

     If any of the payments to be made to Dr. Waksal could result in the
imposition of an excise tax under Section 4999 of the Internal Revenue Code of
1986, as amended, the Company was to pay Dr. Waksal an additional amount to
fully gross him up for such taxes, unless, by reducing the amounts payable to
him by less than 10%, no amounts would be subject to the excise tax, in which
case the payments were to be so reduced.

     The employment agreement also contained confidentiality, non-competition
and non-solicitation provisions.

     For purposes of the employment agreement, we had "cause" to terminate Dr.
Waksal upon (a) a final conviction or plea of guilty or no contest to a felony
involving moral turpitude or (b) willful misconduct that is materially and
demonstrably injurious economically to the Company. Among other events, Dr.
Waksal had "good reason" to terminate his employment with the Company (a) if
there were any material and adverse change in his duties or responsibilities,
(b) if there were a reduction in his base salary, bonus opportunity, or any
material benefit, (c) for any reason during the thirty-day period following the
first anniversary of a change in control of the Company, (d) if the Company
provided a notice of non-renewal of the term, (e) if he were required to
relocate, or (f) if there were a breach of any material provision of the
employment agreement by the Company. Since its execution, this employment
agreement was not amended to reflect any of the changes in Dr. Waksal's
responsibilities or title.

     As of July 22, 2003, the Company accepted the resignation of Dr. Harlan W.
Waksal. Pursuant to his employment agreement, Dr. Waksal received a lump sum
payment totaling approximately $4,424,000 and is entitled to receive for defined
periods of time the continuation of certain benefits including health care and
life insurance coverage through July 2006, with an estimated cost of $38,000. In
addition, all outstanding stock options held by Dr. Harlan W. Waksal, comprising
options to purchase 1,000,000 shares of common stock of the Company at a per
share exercise price of $50.01 that were granted on September 19, 2001, were
deemed amended such that the 666,666 options that remained unvested as of the
date of his resignation vested immediately on that date. The amended stock
option awards can be exercised at any time until the end of the term of such
awards.

     SAMUEL D. WAKSAL.  Dr. Samuel D. Waksal's employment agreement with the
Company which has now been terminated, was substantially the same as the
employment agreement with Dr. Harlan W. Waksal except that: (a) Dr. Samuel D.
Waksal served as the Company's President and Chief Executive Officer; (b) his
base salary was required to be not less than $500,000 per year; and (c) he was
granted stock options to acquire 1,250,000 shares of the Company's common stock.
On May 22, 2002, the Company entered into a Separation Agreement with Dr. Samuel
D. Waksal pursuant to which Dr. Samuel D. Waksal resigned his directorship,
offices and positions within the Company effective as of that date and
terminated his employment agreement with the Company. Pursuant to the terms of
the Separation Agreement, the Company agreed to provide to Dr. Samuel D. Waksal:
(i) a cash payment of $7,000,000; (ii) medical, hospitalization, dental and life
                                        21


insurance programs for a period of three years at the level in effect while Dr.
Samuel D. Waksal was employed by the Company; (iii) term life insurance
purchased by the Company for the benefit of Dr. Samuel D. Waksal or his
designated beneficiaries with a death benefit of $5,000,000, to be maintained by
us for six years; (iv) the immediate vesting of 833,333 unvested employee stock
options held by Dr. Samuel D. Waksal; (v) the payment of all reasonable business
expenses incurred by Dr. Samuel D. Waksal prior to his termination; (vi)
payments that the Dr. Samuel D. Waksal was entitled to receive under Section
8(e) of his employment agreement; (vii) payment of the cost of a crisis
management consultant for a period of six months; and (vii) payment for legal
fees incurred in connection with the negotiation of the Separation Agreement of
up to $35,000. In an action brought by the Company in August 2002 against Dr.
Samuel D. Waksal, the Company is seeking repayment from Dr. Samuel D. Waksal of
all of the above-described amounts paid under the Separation Agreement and the
cancellation of the 833,333 employee stock options that became vested pursuant
to the Separation Agreement.

             REPORT OF THE COMPENSATION AND STOCK OPTION COMMITTEE

     This Report was adopted by the Compensation and Stock Option Committee (the
"Compensation Committee") on April 3, 2003, at which time the Directors signing
this Report constituted the Compensation Committee membership. During 2002,
Robert F. Goldhammer, Peter S. Ringrose and Richard Barth served on the
Compensation Committee. Mr. Goldhammer resigned from the Compensation Committee
on April 3, 2002, Dr. Ringrose resigned from the Compensation Committee on March
19, 2002, and Mr. Barth resigned from the Board of Directors on April 2, 2002.
Mr. Goldhammer and Dr. Ringrose resigned from the Compensation Committee because
it was determined that they were not "independent" as defined under the National
Association of Securities Dealers' ("NASD") listing standards. Each of the
current members of the Compensation Committee is "independent" under that
standard. The Compensation Committee operates under a written charter adopted by
the Board of Directors on November 20, 2002.

OVERALL PHILOSOPHY

     The Company's executive compensation philosophy is based on the premise
that compensation should be set at levels that support the Company's business
strategies and long-term objectives and relate to an individual's performance.
The elements of the executive compensation package are base salary,
participation in annual incentives, and long-term incentive compensation,
including stock options.

     In establishing base salaries, annual and long-term incentive awards, and
awards of stock options, the Compensation Committee considers the executive's
annual review, periodic compensation surveys, including those provided by third
parties covering the biopharmaceutical industry, awards given to the executive
in past years, progress toward or attainment of the Company's corporate goals
and objectives including performance, shareholder return and such other factors
as the Compensation Committee deems appropriate and in the best interests of the
Company (including the cost to the Company of such compensation).

     The Compensation Committee uses no set formulas and may accord different
weight at different times to different factors for each executive. Among the
factors, the Committee considers the progress of the Company's research and
development and capital investment programs, its ability to gain support for
such programs, its ability to attract, motivate and retain talented employees
and its ability to secure capital sufficient for its product development to
achieve rapid and effective commercialization as may be practicable.

DEDUCTIBILITY OF COMPENSATION

     The Compensation Committee has reviewed the impact of Section 162(m) of the
Internal Revenue Code of 1986, as amended (the "Code"), which, beginning in
1994, limits the deductibility of certain otherwise deductible compensation in
excess of $1 million paid to the Chief Executive Officer and certain other
executive officers. It is the general policy of the Company to have its
executive compensation plan qualify to be treated as deductible compensation
whenever, in the judgment of the Compensation Committee, to do so would be
consistent with the objectives of that compensation plan and the best interests
of the Company.
                                        22


CHIEF EXECUTIVE OFFICER COMPENSATION

     Dr. Samuel D. Waksal served as President and CEO until May 22, 2002. From
January 1, 2002 through May 22, 2002, he received no incentive awards, stock
options or cash bonus other than a guaranteed minimum bonus under his employment
agreement relating to 2001 services. Dr. Samuel D. Waksal received $55,917 of
perquisites during 2002. For more information regarding Dr. Samuel D. Waksal's
separation from the Company refer to "Employment and Separation Agreements"
herein.

     Dr. Harlan Waksal became President and CEO on May 23, 2002. Pursuant to the
terms of his employment agreement with the Company dated September 19, 2001, Dr.
Harlan Waksal's base salary for 2002 was $455,000. Dr. Harlan Waksal received no
salary increase for 2002. Pursuant to the terms of his employment agreement, Dr.
Harlan Waksal was entitled to a guaranteed cash bonus for 2002 equal to a
minimum of $545,000. Dr. Harlan Waksal voluntarily declined to accept any cash
bonus relating to 2002 services. Dr. Harlan Waksal received no option grant
during 2002. Dr. Harlan Waksal received in April 2002 a guaranteed minimum bonus
of $545,000 under his employment agreement relating to 2001 services. Dr. Harlan
Waksal received $104,084 of perquisites during 2002.

                                          Compensation and Stock Option
                                          Committee

                                          William R. Miller, Chairman
                                          David M. Kies
                                          Paul B. Kopperl

     The foregoing Report of the Compensation Committee shall not be deemed to
be soliciting material, to be filed with the SEC or to be incorporated by
reference into any of the Company's previous or future filings with the SEC,
except as otherwise explicitly specified by the Company in any such filing.

          COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

     During the fiscal year ended December 31, 2002, the following Directors
served on the Compensation Committee: Robert F. Goldhammer, Richard Barth, David
M. Kies, Paul B. Kopperl, Peter S. Ringrose and William R. Miller, none of whom
is an employee of the Company or any of its subsidiaries nor has ever been an
executive officer of the Company or any subsidiaries. Dr. Ringrose resigned from
the Compensation Committee on March 19, 2002, Mr. Barth resigned from the Board
on April 2, 2002 and Mr. Goldhammer resigned from the Compensation Committee on
April 3, 2002 and from the Board on July 17, 2003. Dr. Ringrose was an executive
officer of BMS prior to his recent retirement from BMS. See, "Certain
Relationships and Related Transactions" for descriptions of the Company's
relationship with BMS.

                                        23


                           SUMMARY COMPENSATION TABLE

     The Summary Compensation Table sets forth the cash and non-cash
compensation awarded to, earned by, or paid to the Company's Chief Executive
Officers during fiscal year 2002 and the four most highly compensated executive
officers (other than the Chief Executive Officers) for each of the years ended
December 31, 2002, 2001 and 2000 who were serving as executive officers at
December 31, 2002 and whose total salary and bonus exceeded $100,000 for the
year ended December 31, 2002.

<Table>
<Caption>
                                                                                   LONG-TERM
                                         ANNUAL COMPENSATION                  COMPENSATION AWARDS
                             --------------------------------------------   -----------------------
                                                                OTHER                    SECURITIES
                                                                ANNUAL      RESTRICTED   UNDERLYING   PAYOUTS    ALL OTHER
NAME AND                             SALARY      BONUS       COMPENSATION     STOCK       OPTIONS      LTIP     COMPENSATION
PRINCIPAL POSITION           YEAR    ($)(1)      ($)(2)          (3)         AWARD(S)       SARS      PAYOUTS       (4)
- ------------------           ----   --------   ----------    ------------   ----------   ----------   -------   ------------
                                                                                        
Harlan W. Waksal(5)........  2002   $444,500   $       --(6)   $104,084(7)    $  --             --     $  --     $    2,750
  President and Chief        2001    451,404      545,000(6)    102,577(7)       --      1,000,000        --          2,550
  Executive Officer          2000    400,000      800,000       105,157(7)       --             --        --          1,700
Daniel S. Lynch(8).........  2002    351,692      360,000(9)    130,958(10)      --        267,500        --          2,750
  Senior Vice President,     2001    223,769      525,000(11)         --         --        260,000        --          1,589
  Finance and Chief
  Financial Officer
Lily W. Lee(12)............  2002    258,654       75,000            --          --         26,250        --          2,668
  Vice President,
    Regulatory               2001    172,436      200,000            --          --         60,000        --          2,344
  Affairs and Biostatistics
S. Joseph Tarnowski........  2002    230,798      100,000            --          --         97,500        --          2,750
  Senior Vice President,     2001    217,808      225,000            --          --         10,000        --          2,306
  Manufacturing Operations   2000    204,750      100,000        36,083(13)      --         24,000        --          1,700
  and Product Development
Clifford R. Saffron(14)....  2002    199,904      125,000            --          --         89,000        --             --
  Senior Vice President and
  General Counsel
Samuel D. Waksal(15).......  2002    215,769           --        55,917(16)      --             --        --      7,001,713(17)
  Former President and       2001    550,000      450,000(18)    268,037(19)      --     1,250,000        --          2,063
  Chief Executive Officer    2000    500,000    1,000,000       302,428(20)      --             --        --          1,700
</Table>

- ---------------
 (1) Amounts shown include compensation deferred pursuant to Section 401(k) of
     the Internal Revenue Code.

 (2) Although the Company has no formal bonus plan, the Company's Compensation
     and Stock Option Committee, in its discretion, may award bonuses to the
     Company's officers and other employees. The Company has paid bonuses based
     on individual and Company performance. Certain employment agreements also
     provide for the payment of minimum guaranteed bonuses. Amounts shown
     include awards paid relative to services rendered in each of the last three
     fiscal years. All bonus awards for each of the last three fiscal years were
     paid in cash. Bonuses are recorded for the period in which they were
     earned.

 (3) Excludes certain perquisites and other personal benefits for each Named
     Executive Officer which did not equal or exceed the lesser of $50,000 or
     10% of such individual's annual salary plus bonus.

 (4) Amounts shown include amounts paid by the Company as a matching
     contribution to employees' 401(k) accounts.

 (5) Dr. Harlan W. Waksal was the Company's President and Chief Executive
     Officer from May 22, 2002 until April 29, 2003, when he became the
     Company's Chief Scientific Officer. He resigned from all positions with the
     Company as of July 22, 2003.

 (6) Pursuant to the terms of an employment agreement dated September 19, 2001,
     Dr. Harlan W. Waksal was guaranteed a minimum annual bonus that is not less
     than the difference between $1,000,000 and his base salary for the relevant
     bonus year. Dr. Harlan W. Waksal elected to forgo his bonus for 2002 and he
     was paid in 2002 his guaranteed bonus for 2001 of $545,000. This employment
     agreement is no longer in effect.

 (7) Includes the cost of tickets to New York City area sporting events for
     personal use at $71,911, $76,703 and $44,950 for 2002, 2001 and 2000,
     respectively.

                                        24


 (8) Mr. Lynch commenced employment with the Company in April 2001. Effective
     April 29, 2003, Mr. Lynch was promoted to Senior Vice President and Chief
     Administrative Officer, Acting Chief Executive Officer.

 (9) Pursuant to the terms of an employment agreement dated September 19, 2001,
     Mr. Lynch is guaranteed a minimum annual bonus that is not less than his
     base salary for the relevant bonus year.

(10) Includes $99,741 for initiation costs, dues and other fees relating to
     membership at a country club.

(11) Consists of a $75,000 sign-on bonus and a performance bonus of $450,000
     paid pursuant to the terms of an employment agreement dated September 19,
     2001.

(12) Dr. Lee commenced employment with the Company in April 2001.

(13) Consists of relocation expenses associated with Dr. Tarnowski joining the
     Company.

(14) Mr. Saffron commenced employment with the Company in February 2002.

(15) Dr. Samuel D. Waksal was the Company's President and Chief Executive
     Officer from March 1987 until May 22, 2002, at which time he resigned all
     positions with the Company.

(16) Includes $24,000 for personal tax planning and financial advice and $15,436
     for personal automobile expenses.

(17) Pursuant to a Separation Agreement dated May 22, 2002, the Company paid Dr.
     Samuel D. Waksal $7,000,000. In an action brought by the Company in August
     2002 against Dr. Samuel D. Waksal, the Company is seeking repayment from
     Dr. Samuel D. Waksal of this and other amounts paid under the Separation
     Agreement.

(18) Pursuant to the terms of an employment agreement dated September 19, 2001,
     Dr. Samuel D. Waksal was guaranteed a minimum annual bonus that is not less
     than the difference between $1,000,000 and his base salary for the relevant
     bonus year. Dr. Samuel D. Waksal's was paid in 2002 his guaranteed bonus
     for 2001 of $450,000. This employment agreement is no longer in effect.

(19) Includes $73,463 for personal tax planning and financial advice and $94,600
     for the cost of tickets to New York City area sporting events for personal
     use.

(20) Includes $135,802 for personal tax planning and financial advice.

                                        25


                          OPTION GRANTS IN FISCAL 2002

     The following table sets forth certain information relating to stock option
grants to the Named Executive Officers during the year ended December 31, 2002.

<Table>
<Caption>
                                       INDIVIDUAL GRANTS
                                       -----------------                               POTENTIAL REALIZABLE VALUE AT
                         NUMBER OF                                                        ASSUMED ANNUAL RATES OF
                         SECURITIES    PERCENT OF TOTAL                                 STOCK PRICE APPRECIATION FOR
                         UNDERLYING     OPTIONS GRANTED    EXERCISE OF                       OPTION TERM(3)($)
                          OPTIONS       TO EMPLOYEES IN     BASE PRICE    EXPIRATION   ------------------------------
NAME                     GRANTED(1)       FISCAL 2002      ($/SHARE)(2)      DATE       0%        5%          10%
- ----                     ----------    -----------------   ------------   ----------   ----   ----------   ----------
                                                                                      
Harlan W. Waksal(9)....        --              --             $   --              --    --    $       --   $       --
Daniel S. Lynch........   200,000(4)(5)       5.62%            30.08       1/16/2012    --     3,782,120    9,583,881
                           60,000(6)         1.69%              6.94        8/5/2012    --       261,871      663,634
                            7,500(4)(5)        .21%            11.91      12/19/2012    --        56,176      142,361
Lily Waiyee Lee........    24,000(4)(5)        .67%            30.08       1/16/2012    --       453,854    1,150,066
                           20,000(6)          .56%              6.94        8/5/2012    --        87,291      221,211
                            6,250(4)(5)         21%            11.91      12/19/2012    --        46,813      118,634
S. Joseph Tarnowski....    70,000(4)(5)       1.97%            30.08       1/16/2012    --     1,323,742    3,354,358
                           20,000(6)          .56%              6.94        8/5/2012    --        87,291      221,211
                            7,500(4)(5)        .21%            11.91      12/19/2012    --        56,176      142,361
Clifford R. Saffron....    60,000(7)         1.69%             18.44       2/14/2012    --       695,809    1,763,317
                           10,000(8)          .28%             21.54       4/17/2012    --       135,464      343,292
                           12,000(6)          .34%              6.94        8/5/2012    --        52,374      132,727
                            7,000(4)(5)        .20%            11.91      12/19/2012    --        52,431      132,870
Samuel D. Waksal(9)....        --              --                 --              --    --            --           --
</Table>

- ---------------
(1) The Company granted options to purchase a total of 3,559,557 shares of
    common stock to employees during 2002.

(2) Options were granted to purchase common stock at an exercise price that
    equaled the fair market value of the common stock at the time of grant.

(3) The amounts set forth in the three columns represent hypothetical gains that
    might be achieved by the holders if the respective options are exercised at
    the end of their terms. These gains are based on assumed rates of stock
    price appreciation of 0%, 5% and 10% compounded annually from the dates the
    respective options were granted.

(4) Options granted on the basis of 2001 performance were granted in 2002 and
    are included in this Table. Options granted on the basis of 2002 performance
    were also granted in 2002 and are included in this Table.

(5) These options are exercisable as to 50% of the shares on each of the first
    and second anniversaries of the date of grant.

(6) These options are exercisable as to 100% of the shares on the second
    anniversary of the date of grant.

(7) These options were granted pursuant to the terms of Mr. Saffron's employment
    agreement entered into as of February 1, 2002 and are exercisable as to 25%
    of the shares on the date of grant and are exercisable as to 25% of the
    shares on each of the first, second and third anniversaries of the date of
    grant.

(8) These options were granted pursuant to the terms of the April 18, 2002
    letter agreement effecting Mr. Saffron's promotion to Senior Vice President
    and Special General Counsel and are exercisable as to 25% of the shares on
    the date of grant and are exercisable as to 25% of the shares on each of the
    first, second, and third anniversaries of the date of grant.

(9) Samuel D. Waksal served as the Company's President and Chief Executive
    Officer during the portion of the fiscal year beginning January 1, 2002 and
    ending May 22, 2002. Harlan W. Waksal served as the Company's President and
    Chief Executive Officer during the portion of the fiscal year beginning on
    May 22, 2002 and ending on December 31, 2002.

                                        26


               OPTION EXERCISES AND FISCAL YEAR-END OPTION VALUES

     The following table sets forth option exercises during the year ended
December 31, 2002 by the Named Executive Officers and the value of the options
held by such persons on December 31, 2002, whether or not exercisable on such
date.

<Table>
<Caption>
                                                           NUMBER OF SHARES
                                                        UNDERLYING UNEXERCISED               VALUE OF UNEXERCISED
                                                              OPTIONS AT                    IN-THE-MONEY OPTIONS AT
                         SHARES                            DECEMBER 31, 2002                 DECEMBER 31, 2002(1)
                       ACQUIRED ON      VALUE      ---------------------------------   ---------------------------------
NAME                   EXERCISE(#)   REALIZED($)   EXERCISABLE(#)   UNEXERCISABLE(#)   EXERCISABLE($)   UNEXERCISABLE($)
- ----                   -----------   -----------   --------------   ----------------   --------------   ----------------
                                                                                      
Harlan W. Waksal.....       0            $0            333,334          666,666                 0           $      0
Daniel S. Lynch......       0             0             81,667          445,833                 0            220,800
Lily Waiyee Lee......       0             0             15,000           95,250                 0             73,600
S. Joseph Tarnowski..       0             0            105,676          142,500           362,726            265,600
Clifford R.
  Saffron............       0             0             15,000           74,000                 0             44,160
Samuel D. Waksal.....       0             0          1,250,000(2)             0                 0                  0
</Table>

- ---------------
(1) The values were calculated by multiplying the closing market price of the
    common stock on December 31, 2002 ($10.62 per share as reported by the
    Nasdaq National Market on that date) by the respective number of shares and
    subtracting the aggregate exercise price, without making any adjustments for
    vesting, termination contingencies or other variables. If the exercise price
    of an option is equal to or greater than $10.62, the option is deemed to
    have no value.

(2) In an action brought by the Company on August 14, 2002 against Dr. Samuel D.
    Waksal in Supreme Court of the State of New York, New York County, the
    Company is seeking the cancellation of 833,333 of these options. See
    "Employment and Separation Agreements".

OTHER BENEFIT PLANS

     The Company has no defined benefit or defined contribution retirement plans
other than the ImClone Systems Incorporated 401(k) Employee Savings Plan (the
"401(k) Plan") established under Section 401(k) of the Internal Revenue Code of
1986, as amended. Contributions to the 410(k) Plan are voluntary, and
substantially all full-time employees are eligible to participate. For 2003, the
Company has elected to make voluntary matching contributions equal to 25% of the
first 6% of an employee's eligible compensation contributed by the employee,
limited to $2,750 per employee. Neither the employee contributions nor the
Company's voluntary matching contributions are invested in the Company's
securities. The Company has made a matching contribution for 2002, which totaled
approximately $314,000. The Company anticipates evaluating the level of the
Company's matching contribution, if any, on an annual basis.

     The following table sets forth certain information regarding equity
compensation plan information for the year ended December 31, 2002.

<Table>
<Caption>
                                                                               NUMBER OF SECURITIES
                                                                              REMAINING AVAILABLE FOR
                                                                               FUTURE ISSUANCE UNDER
                             NUMBER OF SECURITIES TO     WEIGHTED-AVERAGE       EQUITY COMPENSATION
                             BE ISSUED UPON EXERCISE    EXERCISE PRICE OF        PLANS (EXCLUDING
                             OF OUTSTANDING OPTIONS,   OUTSTANDING OPTIONS,   SECURITIES REFLECTED IN
                               WARRANTS AND RIGHTS     WARRANTS AND RIGHTS          COLUMN(A))
PLAN CATEGORY                          (A)                     (B)                      (C)
- -------------                -----------------------   --------------------   -----------------------
                                                                     
Equity Compensation Plans
  Approved by Security
  Holders..................         7,352,647                 $29.54                 2,038,765
Equity Compensation Plans
  Not Approved by Security
  Holders..................         6,160,486                 $28.72                         0
Total......................        13,513,133                 $29.16                 2,038,765
</Table>

                                        27


1998 NON-QUALIFIED STOCK OPTION PLAN

     The Company's 1998 Non-Qualified Stock Option Plan was adopted on May 27,
1998 and has not been approved by shareholders. Under the plan, non-qualified
stock options to purchase the Company's common stock may be granted to persons
who at the time of grant are consultants, advisors or non-officer employees of
the Company or a subsidiary. The maximum number of shares that may be issued
under the plan is 10 million, subject to adjustments for corporate transactions.
The plan is administered by the Compensation and Stock Option Committee (the
"Compensation Committee").

     No options may be granted after May 27, 2008 and each option must have a
term not exceeding 10 years. The number of underlying shares, the exercise price
and other terms and conditions of the stock options granted under the plan are
determined by the Compensation Committee, but, except as otherwise provided by
the Compensation Committee, unvested options are forfeited immediately upon a
termination of employment for any reason except death or disability and vested
options are exercisable for 30 days after such termination. In the case of a
termination by reason of death or disability vested options are generally
exercisable for 12 months.

     Options are not transferable except in the case of death or, if permitted
by the Compensation Committee, to certain members of the immediate family of the
optionee. The Board of Directors may amend or terminate the plan at any time
except for actions which are adverse to options previously granted.

                                        28


                         COMMON STOCK PRICE PERFORMANCE

     The graph below provides a comparison of the cumulative total return
(assuming reinvestment of dividends) for the Company (which paid no dividends)
with The Nasdaq Stock Market (U.S. Companies) Total Return Index and The Nasdaq
Pharmaceutical Stocks Total Return Index for the period from December 31, 1997
through December 31, 2002. The graph assumes $100 was invested in the Company's
common stock and each of the indexes at the beginning of such period. The Nasdaq
Stock Market (U.S. Companies) Total Return Index comprises all domestic common
shares traded on the Nasdaq National Market and the Nasdaq SmallCap Market. The
Nasdaq Pharmaceutical Stocks Total Return Index represents all companies,
including biotechnology companies, trading on Nasdaq classified under the
Standard Industrial Classification Code for pharmaceuticals.

                   COMPARISON OF FIVE YEAR TOTAL RETURN AMONG
                   IMCLONE SYSTEMS INCORPORATED COMMON STOCK,
          NASDAQ STOCK MARKET (U.S. COMPANIES) TOTAL RETURN INDEX AND
                NASDAQ PHARMACEUTICAL STOCKS TOTAL RETURN INDEX

                              (PERFORMANCE GRAPH)

<Table>
<Caption>
                                                                                       NASDAQ
                                                                                   PHARMACEUTICAL
                                                             IMCL      NASDAQ US       STOCKS
                                                           ---------   ---------   --------------
                                                                          
12/31/97.................................................  $  100.00    $100.00       $100.00
12/31/98.................................................  $  111.12    $141.00       $126.95
12/31/99.................................................  $  485.95    $261.96       $239.34
12/31/00.................................................  $1,079.34    $157.56       $298.54
12/31/01.................................................  $1,139.69    $125.01       $254.43
12/31/02.................................................  $  260.51    $ 86.44       $164.38
</Table>

     The material under the caption "Common Stock Price Performance" shall not
be deemed to be soliciting material, to be filed with the SEC or to be
incorporated by reference into any of the Company's previous or future filings
with the SEC, except as otherwise explicitly specified by the Company in any
such filing.

                                        29


                     CERTAIN RELATIONSHIPS AND TRANSACTIONS

RELATIONSHIP WITH BRISTOL-MYERS SQUIBB COMPANY

     One of the Company's Directors, Dr. Andrew G. Bodnar is also an officer of
Bristol-Myers Squibb Company, a Delaware corporation ("BMS"). The Company's
relationship with BMS is described below.

     On September 19, 2001, the Company entered into an acquisition agreement
(the "Acquisition Agreement") with BMS and Bristol-Myers Squibb Biologics
Company, a Delaware corporation which is a wholly-owned subsidiary of BMS ("BMS
Biologics"), providing for the tender offer by BMS Biologics to purchase up to
14,392,003 shares of the Company's common stock for $70.00 per share, net to the
seller in cash. The tender offer by BMS Biologics, available to all
stockholders, allowed for the Company's then-current employees and Directors who
held exercisable options to purchase the Company's shares of common stock having
exercise prices less than $70.00 per share to conditionally exercise any or all
of those options and tender the underlying shares in the tender offer. In
connection with the Acquisition Agreement, the Company entered into a
stockholder agreement with BMS and BMS Biologics, dated as of September 19, 2001
(the "Stockholder Agreement"), pursuant to which the Company agreed with BMS and
BMS Biologics to various arrangements regarding the respective rights and
obligations of each party with respect to, among other things, the ownership of
shares of the Company's common stock by BMS and BMS Biologics. The Stockholder
Agreement also sets forth BMS's (i) limitation on additional purchases of
shares, (ii) option to purchase shares in the event of dilution and (iii)
restrictions as to transfer of shares. Concurrently with the execution of the
Acquisition Agreement and the Stockholder Agreement, the Company entered into a
development, promotion, distribution and supply agreement (the "Commercial
Agreement") with BMS and E.R. Squibb & Sons, L.L.C., a Delaware limited
liability company which is a wholly-owned subsidiary of BMS ("E.R. Squibb"),
relating to ERBITUX, the Company's lead therapeutic product candidate, pursuant
to which, among other things, the parties are co-developing and co-promoting
ERBITUX in the United States and Canada, and co-developing and co-promoting
ERBITUX in Japan (either together or co-exclusively with Merck KGaA).

     On March 5, 2002, the Company amended the Commercial Agreement with E.R.
Squibb and BMS. The amendment changed certain economics of the Commercial
Agreement and has expanded the clinical and strategic role of BMS in the ERBITUX
development program. One of the principal economic changes to the Commercial
Agreement is that the Company received $140,000,000 on March 7, 2002 and an
additional payment of $60,000,000 was received on March 5, 2003. Such payments
are in lieu of the $300,000,000 payment the Company would have received on
acceptance by the United States Food and Drug Administration ("FDA") of the
ERBITUX Biologics License Application under the original terms of the Commercial
Agreement. In addition, the Company agreed to resume construction of the
Company's Multiple Product Facility as soon as reasonably practicable after the
execution of the amendment.

     On October 29, 2001, pursuant to the Acquisition Agreement, BMS Biologics
accepted for payment pursuant to the tender offer 14,392,003 shares of the
Company's common stock on a pro rata basis from all tendering shareholders and
those conditionally exercising stock options.

     The Stockholder Agreement gave BMS the right to nominate two Directors so
long as its ownership interest in the Company is 12.5% or greater. Initially,
BMS designated Dr. Peter S. Ringrose, BMS's former Chief Scientific Officer and
President, Pharmaceutical Research Institute, and Dr. Andrew G. Bodnar, BMS's
Senior Vice President, Strategy and Medical & External Affairs, as the BMS
Directors. BMS continues to have an ownership interest greater than 12.5% and to
possess the right to nominate two Directors. However, BMS has not yet nominated
a replacement to fill the seat on the Board vacated by Dr. Ringrose, who retired
in 2002 from his position at BMS, and also resigned from his Director position
with the Company. Therefore, the Company currently expects that BMS will
nominate only one Director for election at the meeting.

     In exchange for the rights granted to BMS under the amended Commercial
Agreement, the Company can receive up-front and milestone payments totaling
$900,000,000 in the aggregate, of which $200,000,000 was received on September
19, 2001, $140,000,000 was received on March 7, 2002, $60,000,000 was received
on March 5, 2003, $250,000,000 is payable upon receipt of marketing approval
from the FDA with respect to
                                        30


the initial indication for ERBITUX and $250,000,000 is payable upon receipt of
marketing approval from the FDA with respect to a second indication for ERBITUX.
All such payments are non-refundable and non-creditable. Except for the
Company's expenses incurred pursuant to a co-promotion option that the Company
has exercised, E.R. Squibb is responsible for 100% of the distribution, sales
and marketing costs for ERBITUX in the United States and Canada, and the Company
and E.R. Squibb will each be responsible for 50% of the distribution, sales,
marketing costs and other related costs and expenses in Japan. The Commercial
Agreement provides that E.R. Squibb shall pay the Company distribution fees
based on a percentage of annual sales of ERBITUX by E.R. Squibb in the United
States and Canada. The distribution fee is 39% of net sales in the United States
and Canada. The Commercial Agreement also provides that the distribution fees
for the sale of ERBITUX in Japan by E.R. Squibb or the Company shall be equal to
50% of operating profit or loss with respect to such sales for any calendar
month. In the event of an operating profit, E.R. Squibb will pay the Company the
amount of such distribution fee, and in the event of an operating loss, the
Company will credit E.R. Squibb the amount of such distribution fee. The
Commercial Agreement provides that the Company will be responsible for the
manufacture and supply of all requirements of ERBITUX in bulk form for clinical
and commercial use in the United States, Canada and Japan and that E.R. Squibb
will purchase all of its requirements of ERBITUX in bulk form for commercial use
from the Company. The Company will supply ERBITUX in bulk form for clinical use
at the Company's fully burdened manufacturing cost plus a mark-up of 10%. In
addition to the up-front and milestone payments, the Commercial Agreement
provides that distribution fees for the United States, Canada and Japan and the
10% mark-up on the commercial supply of ERBITUX, E.R. Squibb is also responsible
for 100% of the cost of all clinical studies other than those studies undertaken
post-launch which are not pursuant to an Investigational New Drug Application
(e.g. Phase IV studies), the cost of which will be shared equally between E.R.
Squibb and the Company. As between E.R. Squibb and the Company, each will be
responsible for 50% of the cost of all clinical studies in Japan. The Company
has also agreed, and may agree in the future, to share with E.R. Squibb, on
terms other than the foregoing, costs of clinical trials that The Company
believes are not potentially registrational but should be undertaken prior to
launch in the United States, Canada or Japan.

     On January 2, 2002, the Company executed a letter of intent with Lonza
Biologics plc ("Lonza") to enter into a long-term supply agreement. The
long-term supply agreement would have applied to a large scale manufacturing
facility that Lonza is constructing, which would have been able to produce
ERBITUX in 20,000 liter batches. The Company paid Lonza $3,250,000 upon
execution of the letter of intent for the exclusive right to negotiate a
long-term supply agreement for a portion of the facility's manufacturing
capacity. In September 2002, the Company wrote-off the deposit because the
exclusive negotiation period ended on September 30, 2002. In light of the
assistance the Company provided to BMS with respect to preserving and then
relinquishing the manufacturing capacity described above, BMS paid the Company
$3,250,000 in April 2003.

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

     Section 16(a) of the Securities Exchange Act of 1934 requires the Company's
officers and directors, and persons who own more than ten percent of a
registered class of the Company's equity securities, to file with the SEC
reports of ownership of the Company's securities and changes in reported
ownership. Officers, directors and greater than ten percent shareholders are
required by SEC rules to furnish the Company with copies of all Section 16(a)
reports they file.

     Based solely on a review of the copies of such reports furnished to the
Company, or written representations from the reporting persons that no Form 5
was required, the Company believes that, during the fiscal year ended December
31, 2002, all Section 16(a) filing requirements applicable to the Company's
executive officers, directors, and greater than ten percent beneficial owners
were met.

                                        31


                         REPORT OF THE AUDIT COMMITTEE

MEMBERSHIP AND ROLE OF THE AUDIT COMMITTEE

     This report was adopted by the Audit Committee on August 12, 2003. The
Audit Committee consists of the following members of the Company's Board of
Directors: Paul B. Kopperl, Chairman, William R. Miller, Arnold Levine and John
A. Fazio. Mr. Fazio was appointed to the Board of Directors and the Audit
Committee on February 27, 2003. Mr. Fazio is an Audit Committee Financial
Expert, as that term is defined by the rules of the Securities and Exchange
Commission. During 2002, Andrew G. Bodnar and Richard Barth served on the Audit
Committee. Dr. Bodnar resigned from the Audit Committee on March 4, 2002,
because he was not "independent" as defined under the National Association of
Securities Dealers' listing standards and Mr. Barth resigned from the Board of
Directors on April 2, 2002. Each of the current members of the Audit Committee
is "independent" as defined under the National Association of Securities
Dealers' listing standards. The Audit Committee formerly operated under a
written charter adopted by the Board of Directors on June 14, 2000, a copy of
which was included as an appendix to the Company's Proxy Statement for the 2000
fiscal year, and currently operates under a written charter adopted by the Board
of Directors on August 14, 2003, a copy of which is included as Appendix A to
this proxy statement. Among other matters, the Audit Committee in its oversight
role reviews and reassesses the adequacy of the charter and the performance of
the Audit Committee thereunder at least annually. The Audit Committee held seven
meetings during the fiscal year ended December 31, 2002.

REVIEW OF THE COMPANY'S AUDITED FINANCIAL STATEMENTS FOR FISCAL YEAR ENDED
DECEMBER 31, 2002

     The Audit Committee reviewed and discussed the audited financial statements
of the Company for the fiscal year ended December 31, 2002 with the Company's
management and KPMG LLP, the Company's independent auditors. This process
included an assessment of the quality, not just the acceptability, of the
accounting principles utilized, the reasonableness of significant estimates and
judgments and the clarity of disclosures in the financial statements. In
addressing the quality of management's accounting judgments, the Audit Committee
asked for and received management's representations that the audited financial
statements of the Company have been prepared in conformity with accounting
principles generally accepted in the United States of America and have repeated
their general preference that conservative policies be followed when more than
one accounting option is available.

     The Audit Committee also discussed with the independent auditors the
matters required to be discussed by applicable statements on Auditing Standards
concerning communication with Audit Committees, as currently in effect, and,
with and without management present, reviewed and discussed the results of the
independent auditors' examination of the financial statements.

     Consistent with Independence Standards Board Standard No. 1 (Independence
Discussion with Audit Committees), as currently in effect, the Audit Committee
obtained from KPMG LLP a formal written statement describing all relationships
between it and the Company that might bear on the auditors' independence from
the Company and its management. The Audit Committee discussed with management
and with the independent auditors the provision of non-audit services provided
by KMPG LLP and any relationships that might have impacted or may impact the
auditors' objectivity and independence and has satisfied itself as to the
auditors' independence.

     At each of its meetings in 2002 (and in prior years) the Audit Committee
followed the practice in executive session whereby each of the Company's
principal legal, compliance, accounting and finance managers as well as KPMG LLP
had the opportunity individually to raise and discuss any issues or concerns
that he, she or they may have had about the adequacy and proper, timely
functioning of the Company's control, reporting, disclosure and compliance
systems and procedures.

     In July 2002 the Audit Committee established an internal audit function
reporting directly to the Committee and conducted a search for a qualified
individual to serve in this capacity. In September 2002 the Committee directed
the Company to hire a qualified person as Vice President, Internal Audit and
thereafter provided oversight of his duties and performance.
                                        32


     As previously disclosed in the Company's 2002 Annual Report on Form 10-K
and in other filings with the Securities and Exchange Commission on March 30,
2003, consistent with its Charter and as confirmed by the Board of Directors,
the Audit Committee undertook an investigation of potential withholding tax
liabilities and other matters related to the exercise of certain Company common
stock options and warrants by then-current and former officers, other employees
and directors. The Audit Committee engaged Simpson Thacher & Bartlett LLP to
conduct the investigation in conjunction with Company counsel, Davis Polk &
Wardwell. The Company's independent auditors, KPMG LLP, were kept informed of
the status and findings of the investigation on an ongoing basis throughout the
process and at its conclusion. As a result of the investigation, the Company
restated its financial statements previously filed with the Securities and
Exchange Commission for the fiscal years ended December 31, 2000 and 2001;
amended its first three quarterly reports on Form 10-Q for the fiscal year ended
December 31, 2002; initiated certain Board of Director and executive management
changes; and, as more fully described in the Company's Annual report on Form
10-K for the fiscal year ended December 31, 2002, continued the assessment and,
by instituting certain remedial actions, the strengthening of the Company's
internal controls, compliance procedures and disclosure processes.

     In performing all of these functions, the Audit Committee acted and
continued to act only in an oversight capacity on behalf of the Board of
Directors. In its oversight role, the Audit Committee necessarily relies on the
procedures, work and assurances of the Company's management, which has the
primary responsibility for financial statements and reports, and of the
independent auditors, who, in their report, express an opinion on the conformity
of the Company's audited financial statements to accounting principles generally
accepted in the United States of America.

     Based on the Audit Committee's review and discussions noted above, on June
23, 2003, the Audit Committee recommended to the Board of Directors that the
Company's audited financial statements be included in the Company's Annual
Report on Form 10-K for the fiscal year ended December 31, 2002.

     The Audit Committee has recommended, subject to ratification by the
stockholders, that KPMG LLP be selected as the Company's independent auditors
for the fiscal year ending December 31, 2003.

     This report is submitted on behalf of the current members of the Audit
Committee, except Mr. Fazio who did not join the Audit Committee until February
27, 2003.

                                          Audit Committee

                                          Paul B. Kopperl, Chairman
                                          Arnold J. Levine
                                          William R. Miller

     The foregoing Report of the Audit Committee shall not be deemed to be
soliciting material, to be filed with the SEC or to be incorporated by reference
into any of the Company's previous or future filings with the SEC, except as
otherwise explicitly specified by the Company in any such filing.

                             FEES PAID TO KPMG LLP

AUDIT FEES

     The aggregate fees billed by KPMG LLP in connection with its audit of the
Company's annual financial statements and its review of the financial statements
included in the Company's Form 10-Qs were $174,000 and $1,512,177 for the fiscal
years 2001 and 2002, respectively.

FINANCIAL INFORMATION SYSTEMS DESIGN AND IMPLEMENTATION FEES

     The Company did not engage KPMG LLP to provide services for the Company
regarding financial information systems design and implementation during 2001 or
2002.

                                        33


ALL OTHER FEES

     KPMG LLP's fees for all other professional services provided to the Company
incurred during 2001 and 2002 were $240,000 and $104,175, respectively,
including audit related services of $96,000 and $10,750, respectively, and
non-audit related services of $144,000 and $93,425, respectively. Audit related
services included fees related to the review of SEC registration statements and
various technical accounting consultations. Non-audit related services consisted
primarily of fees related to tax services. The Audit Committee has considered
whether the provision of all other services by KPMG LLP is compatible with
maintaining KPMG LLP's independence and concluded that KPMG LLP is
"independent."

                                        34


                                 PROPOSAL NO. 2

          APPROVAL OF AN AMENDMENT TO THE IMCLONE SYSTEMS INCORPORATED
                             2002 STOCK OPTION PLAN

     On April 3, 2002, the Board of Directors adopted and, on June 11, 2002, the
shareholders approved the ImClone Systems Incorporated 2002 Stock Option Plan
for the purpose of enhancing the ability of the Company and its subsidiaries to
attract and retain officers, employees, directors and consultants of outstanding
ability and to provide officers, employees, directors and consultants with an
interest in the Company parallel to that of the Company's shareholders. The
Compensation Committee will assess the appropriateness of granting options to
such individuals based upon their performance and the principles of solid
corporate governance.

     The proposed amendment to the plan would increase the maximum total number
of shares of common stock currently available for grant of options under the
plan from 3,300,000 shares to 6,600,000 shares, and increase the number of
shares of common stock with respect to which incentive stock options may be
granted under the plan from 825,000 shares to 1,650,000 shares. The affirmative
vote of a majority of the outstanding shares present and entitled to vote at the
annual meeting is required to approve the amendment to the plan. A brief
description of the major provisions of the plan including the proposed
amendments to the plan is set forth below to facilitate an informed decision by
the shareholders entitled to vote on the approval of the amendment to the plan.
This summary highlights only selected information from the plan and does not
contain all of the information that may be important to you. To understand the
terms of the plan fully, you should read the full text of the existing plan, a
copy of which is attached hereto as Appendix B.

SUMMARY OF PLAN:

     Administration.  The plan is required to be administered by a committee
(the "Committee") consisting of at least two members of the Board of Directors
who are "non-employee directors" within the meaning of Rule 16b-3 as promulgated
under Section 16 of the Securities Exchange Act of 1934, as amended and who are
also "outside directors" within the meaning of Section 162(m) of the Internal
Revenue Code. The Committee has broad discretion, subject to the terms of the
plan, to approve the selection of participants, prescribe the terms and
conditions of options and establish rules and regulations for the interpretation
and administration of the plan.

     In order to administer the plan in an efficient manner, the Committee may
delegate to officers or employees of the Company or any subsidiary, and to
service providers, the authority, subject to such terms as the Committee shall
determine, to perform administrative functions with respect to the plan and
option awards.

     Under the plan, members of the Committee shall not be personally liable for
any actions taken in good faith with respect to the plan and shall, to the
extent permitted by law, be fully indemnified by the Company with respect to any
such action or determination.

     Eligibility.  Individuals eligible to receive options under the plan are
officers, employees, directors and consultants of the Company and its
subsidiaries selected by the Committee; provided that only employees of the
Company and its subsidiaries may be granted incentive stock options.

     Stock Subject to the Plan.  Common stock available for issue or
distribution under the plan comprises authorized and unissued shares or shares
reacquired by the Company in any manner. Subject to adjustment under the plan,
the maximum total number of shares of common stock which currently is available
for the grant of options under the plan is 3,300,000. The stockholders are being
asked to approve an amendment to the plan to increase the number of shares of
common stock that are authorized to be issued under the plan from 3,300,000 to
6,600,000. For purposes of this limitation, any common stock subject to an
option which is canceled, forfeited or expires prior to exercise -- whether such
option was granted under this or under the 1998 Non-Qualified Stock Option Plan,
as amended, the 1996 Non-Qualified Stock Option Plan, as amended, or the 1996
Incentive Stock Option Plan, as amended (together the "Prior Plans") -- again
becomes available for grant under the plan. In addition, any shares of common
stock tendered and/or withheld for payment of all or a portion of an option or
any applicable withholding taxes again becomes available for the grant of an
option
                                        35


under the plan. The Company may, but is not required to, use the proceeds it
receives in connection with the exercise of an option under this plan or under
the Prior Plans for exercises occurring after June 11, 2002 to purchase shares
of its common stock in the open market and any such shares may be used for the
issuance of options under this plan. Subject to adjustment under the plan, no
employee shall be granted, during any three (3) year period, options to purchase
more than 3,300,000 shares of common stock.

     Subject to adjustment under the plan, the aggregate number of shares of
common stock with respect to which incentive stock options may be granted under
the plan shall not exceed 825,000 shares of common stock. The shareholders are
being asked to approve the increase of this number to 1,650,000 shares of common
stock. Any shares of common stock subject to an incentive stock option granted
under the plan or the 1996 Incentive Stock Option Plan, as amended, which is
canceled, forfeited or expires prior to exercise shall again be counted toward
the aggregate number of shares available for the grant of incentive stock
options under this plan.

     No further grants may be made under the Prior Plans.

     The market value of the Company's common stock as reported on Nasdaq as of
August 20, 2003 was $40.81 per share.

     Nothing in the plan prohibits the Company from adopting other equity
compensation programs for employees of the Company and its subsidiaries,
including employees eligible for grants under the plan.

     Type of Awards.  Incentive stock options and nonqualified stock options may
be granted under the plan.

     Purchase Price.  The purchase price per share of common stock purchasable
under an option shall be determined by the Committee and shall not be less than
100% of the fair market value of the common stock on the date of grant.

     Option Term.  Unless otherwise provided at the time of grant, the term of
each option shall be ten (10) years from the date the option is granted. Unless
otherwise provided at the time of grant, upon the death or disability of a
participant, options (other than incentive stock options) that would otherwise
remain exercisable following such death or disability shall remain exercisable
for one year following such death or disability, notwithstanding the term of the
option.

     Exercisability; Method of Exercise.  Each option shall vest and become
exercisable at a rate determined by the Committee on the date of grant.

     Options may be exercised, in whole or in part, by written notice to the
Company, specifying the number of shares to be purchased together with payment
in full of the exercise price. The exercise price may be paid by (i) cash or
certified check or bank check, (ii) surrender of common stock held by the
optionee for at least six (6) months (or such longer or shorter period as may be
required to avoid a charge to earnings for accounting purposes) or the
attestation of ownership of such shares, in either case, if so permitted by the
Company, (iii) through a broker-assisted same-day sale, (iv) through additional
methods prescribed by the Committee or (v) by any combination of the foregoing,
to the extent permitted by applicable law.

     Termination of Continuous Service.  Unless otherwise provided at the time
of grant, upon a termination of continuous service by an optionee, all unvested
options shall terminate and all vested options shall remain exercisable for 30
days thereafter (one year in the event of death or disability); provided, that,
if such termination is for cause, all options (whether or not vested) shall
terminate and cease to be exercisable.

     Withholding Tax.  The Company has the right to require any optionee to pay
to the Company any amount of taxes which the Company shall be required to
withhold with respect to the exercise of an option. Such obligation may be
satisfied as follows:(i) in cash or (ii) with the consent of the Committee and
in its sole discretion, the participant may elect to have the Company withhold
shares of common stock having a fair market value equal to the amount of the
withholding tax obligation as determined by the Company.

     Acceleration of Exercisability.  Unless otherwise provided at the time of
grant, upon the occurrence of a Change in Control (as defined in the plan), all
options shall automatically become vested and exercisable in full.
                                        36


     Forfeiture.  Unless otherwise provided at the time of grant, in the event
of a serious breach of conduct by a participant or former participant, the
Committee may (i) cancel any outstanding option granted to such participant or
former participant, in whole or in part, whether or not vested, and/or (ii) if
such conduct or activity occurs within one (1) year following the exercise of an
option, require such participant or former participant to repay to the Company
any gain realized upon the exercise of such option.

     Adjustments.  The Committee will determine the appropriate adjustments to
be made in order to prevent dilution or enlargement of the benefits or potential
benefits intended to be made available under the plan or with respect to an
option upon the occurrence of certain events affecting the capitalization of the
Company.

     Termination and Amendment of the Plan.  Subject to earlier termination
pursuant to the terms of the plan, the plan shall have an indefinite term;
provided that, the ability to grant incentive stock options will terminate on
April 3, 2012. The Board may amend, suspend or terminate the plan at any time;
provided, that, (a) no such amendment shall be made without shareholder approval
if such approval is necessary to comply with applicable law, regulation or stock
exchange rule and (b) except as provided in the plan, no amendment shall be made
that would adversely affect rights previously granted under the plan.

GENERAL FEDERAL TAX CONSEQUENCES

     The following summary of the material federal income tax consequences to
the Company is based on current law, is for general information only and is not
tax advice.

     Section 162(m) Limitation.  Subject to a limited number of exceptions,
Section 162(m) denies a deduction to a publicly held corporation for payments of
remuneration to certain employees to the extent the employee's remuneration for
the taxable year exceeds $1,000,000. For this purpose, remuneration attributable
to stock options is included within the $1,000,000 limitation. However, to the
extent that certain procedural requirements are met (e.g., the plan is approved
by the stockholders of the Company, grants are made by the Committee, the
exercise price is equal to the fair market value of the underlying shares upon
grant, etc.), gain from the exercise of stock options should not be subject to
the $1,000,000 limitation.

     The Company has attempted to structure the plan in such a manner that the
remuneration attributable to the stock options will not be subject to the
$1,000,000 limitation. The Company has not, however, requested a ruling from the
Internal Revenue Service or an opinion of counsel regarding this issue.

     Non-Qualified Stock Options.  An individual receiving non-qualified stock
options should not recognize taxable income at the time of grant. A participant
should generally recognize ordinary compensation income in an amount equal to
the excess, if any, in the fair market value of the option shares on exercise of
the non-qualified stock options over the exercise price thereof. In general,
subject to the limitations set forth in Section 162(m) and discussed above, the
Company is entitled to deduct from its taxable income the amount that the
participant is required to include in ordinary income at the time of such
inclusion.

     Incentive Stock Options.  An individual granted an incentive stock option
will not generally recognize taxable income at the time of grant or, subject to
certain conditions, at the time of exercise, although he or she may be subject
to alternative minimum tax. In general, if a disqualifying disposition should
occur (i.e., the shares acquired upon exercise of the option are disposed of
within the later of two years from the date of grant or one year from the date
of exercise), a participant will generally recognize ordinary compensation
income in the year of disposition in an amount equal to the excess, if any, of
the fair market value of the option shares at the time of exercise (or, if less,
the amount realized on disposition), over the exercise price thereof. The
Company is not entitled to any deduction on account of the grant of the
incentive stock options or the participant's exercise of the option to acquire
common stock. However, in the event of a subsequent disqualifying disposition of
such shares of common stock acquired pursuant to the exercise of an incentive
stock option under circumstances resulting in taxable compensation to the
participant, subject to the limitations set forth in Section 162(m) and
discussed above, in general, the Company should be entitled to a tax deduction
equal to the amount treated as taxable compensation to the participant.

                                        37


REGISTRATION WITH THE SEC

     The Company has filed a registration statement covering the offering of the
shares under the plan with the SEC pursuant to the Securities Act of 1933, as
amended.

NEW PLAN BENEFITS

     Because future participation in the plan and the level of participation
will vary, it is not possible to determine the value of benefits which may be
obtained by those eligible to participate in the plan.

     THE BOARD RECOMMENDS A VOTE "FOR" THE APPROVAL OF THE AMENDMENT TO THE
IMCLONE SYSTEMS INCORPORATED 2002 STOCK OPTION PLAN (PROPOSAL NO. 2 ON YOUR
PROXY CARD).

                                        38


                                 PROPOSAL NO. 3
                     APPROVAL OF THE ANNUAL INCENTIVE PLAN

     The Board of Directors has approved and recommends that stockholders
approve the adoption of the Annual Incentive Plan which is intended to comply
with Section 162(m) of the Internal Revenue Code. The Annual Incentive Plan, if
approved by stockholders, will provide for the payment of bonuses to each
executive officer of the Company and its subsidiaries, and other key executives
who are selected to participate in the Annual Incentive Plan by the Compensation
Committee. The bonuses will be based on a participant's share of performance
awards based on the satisfaction of performance objectives as described below.

     On January 24, 2003, the Board of Directors approved the Annual Incentive
Plan. The Annual Incentive Plan permits the Compensation Committee to grant
performance awards based upon pre-established performance goals to executives of
the Company and its subsidiaries selected by the Compensation Committee, whether
or not such executives, at the time of grant, are subject to the limit on
deductible compensation under Section 162(m) of the Internal Revenue Code.

     In order to qualify for deductibility under Section 162(m) of the Internal
Revenue Code, the Annual Incentive Plan, including the performance goals for
determining performance awards ("Performance Awards") set forth in the Annual
Incentive Plan must be approved by the stockholders. If the Annual Incentive
Plan is not approved by the Company's stockholders, no Performance Awards
granted under the Annual Incentive Plan will be paid whether or not the
Performance Awards would otherwise be earned.

     Stockholder approval of the Annual Incentive Plan is recommended by the
Board of Directors in order to continue to provide an incentive to executive
officers and other selected key executives of the Company and its subsidiaries
to contribute to the growth, profitability and increased stockholder value of
the Company, to retain such executives, and to endeavor to maintain the
tax-deductible status of such incentive payments to the Company's Chief
Executive Officer and four most-highly paid executive officers at year end who
are named in the Company's Proxy Statement for the year in which such amounts
are claimed as a deduction by the Company. A copy of the Annual Incentive Plan
is attached to this Proxy Statement as Appendix C. The description of the plan
that follows is qualified in its entirety by reference to the plan as attached.

     The Annual Incentive Plan will be administered by the Compensation
Committee, which committee must be composed of at least two members of the Board
of Directors who qualify as "outside directors" within the meaning of Section
162(m) of the Internal Revenue Code. The Compensation Committee will select plan
participants from among executive officers and other key executives of the
Company and its subsidiaries. The number of participants in the Annual Incentive
Plan is not determinable from year to year. Under the Annual Incentive Plan, the
Compensation Committee may, in its sole discretion, grant Performance Awards to
eligible employees.

     Performance Awards.  Under the Annual Incentive Plan, the Compensation
Committee has the authority to grant Performance Awards which provide
participants with the right to such an award based upon the achievement of one
or more levels of performance required to be attained with respect to a
performance goal, as defined below (a "Performance Goal"), set by the
Compensation Committee during a Performance Period (the "Performance
Objective"). The Annual Incentive Plan contemplates that the following
Performance Goals may be selected by the Compensation Committee and shall mean
or may be expressed in terms of any of the following business criteria: revenue;
earnings before interest, taxes, depreciation and amortization; funds from
operations; funds from operations per share; operating income or (losses); pre
or after tax income or (losses); cash available for distribution; cash available
for distribution per share; net earnings or (losses); earnings per share
(losses); return on equity; return on assets; share price performance;
improvements in the Company's attainment of expense levels; and implementing or
completion of critical projects, including, without limitation, strategic plans,
or improvement in cash-flow (before or after tax); development of critical
projects; or product development or progress relating to research and
development. A Performance Goal may be measured over a Performance Period on a
periodic, annual, cumulative or average basis and may be established on a
corporate-wide basis or established with respect to one or more operating units,
divisions, subsidiaries, acquired businesses, minority investments, partnerships
or joint ventures. For purposes of the Annual Incentive Plan, a Performance
Period shall mean the calendar year, or such other shorter or longer
                                        39


period designated by the Compensation Committee, during which performance will
be measured in order to determine a participant's entitlement to receive payment
of a Performance Award.

     The Annual Incentive Plan contemplates that the Compensation Committee will
establish the Performance Objective for each Performance Award, consisting of
one or more business criteria permitted as a Performance Goal hereunder, one or
more levels of performance with respect to each such criteria and the amount or
amounts payable or other rights to which the participant will be entitled upon
achievement of such levels of performance. More than one Performance Goal may be
incorporated in a Performance Objective, in which case achievement with respect
to each Performance Goal may be assessed individually or in combination with
each other. The Compensation Committee may, in connection with the establishment
of Performance Objectives for a Performance Period, establish a matrix setting
forth the relationship between performance on two or more Performance Goals and
the amount of the Performance Award payable for that Performance Period. The
level or levels of performance specified with respect to a Performance Goal may
be established in absolute terms, as objectives relative to performance in prior
periods, as an objective compared to the performance of one or more comparable
companies or an index covering multiple companies, or otherwise as the
Compensation Committee may determine. Performance Objectives may differ for
Performance Awards granted to any one participant or to different participants.

     The Performance Objective applicable to a Performance Period must be
established by the Compensation Committee prior to, or reasonably promptly
following the inception of, a Performance Period, but no later than the earlier
of the date that is 90 days after the commencement of the Performance Period or
the date prior to the date on which twenty-five percent of the Performance
Period has elapsed, as required by Section 162(m) of the Internal Revenue Code.

     Upon certification of the achievement of Performance Objectives by the
Compensation Committee which entitle a participant to the payment of a
Performance Award, unless such participant has elected to defer payment upon
approval by the Compensation Committee, the award shall be settled in cash or
other property. A participant will not be granted Performance Award for any
Performance Periods commencing in a calendar year that permit the participant in
the aggregate to earn a cash payment or payment in other property, in excess of
$2,000,000.

     Miscellaneous Provisions.  The Compensation Committee is authorized at any
time during or after a Performance Period, in its sole and absolute discretion,
to reduce or eliminate any Performance Awards (in whole or in part), of any
participant, for any reason, including changes in the participant's position or
duties with the Company or any subsidiary during a Performance Period, whether
due to any termination of employment (including death, disability, retirement,
voluntary termination or termination with or without cause) or otherwise;
provided, that, no such reduction or elimination may cause Performance Awards to
fail to qualify as qualified performance based compensation under Section 162(m)
of the Internal Revenue Code. To the extent necessary to preserve the intended
economic effects of the Annual Incentive Plan to the Company and its
subsidiaries and the participants, the Compensation Committee is also authorized
during or after a Performance Period to adjust the Performance Objectives, the
Performance Awards, or both (whichever is applicable) to take into account a
change in corporate capitalization, a corporate transaction, any partial or
complete liquidation of the Company or any subsidiary or a change in accounting
rules; provided that, no such adjustment may cause Performance Awards to fail to
qualify as qualified performance based compensation under Section 162(m) of the
Internal Revenue Code.

     Under the Annual Incentive Plan, each participant (upon advance approval of
the Compensation Committee) will have the right to defer receipt of part or all
of any payment due with respect to a Performance Award, subject to the terms,
conditions and administrative guidelines as the Compensation Committee shall
determine from time to time.

     In the event of a Change in Control (as defined in the Annual Incentive
Plan), (i) with respect to the Performance Awards, any incomplete Performance
Periods in effect on the date the Change in Control occurs shall end on the date
of such change, and the Compensation Committee will (A) determine the extent to
which the Performance Objective with respect to such Performance Periods has
been met based on such audited or unaudited financial information then available
as it deems necessary, and (B) cause to be paid to
                                        40


each participant partial or full Performance Awards for the Performance Periods
based on the Compensation Committee's determination of the degree of attainment
of the Performance Objective. Following a Change in Control, the Compensation
Committee may not reduce or eliminate any Performance Award (in whole or in
part). However, the Performance Award paid to the participant will be prorated
to reflect the period of time elapsed during the Performance Period. Any
resulting amount due to a participant will be paid in a cash lump sum no later
than 15 days after a Change in Control, unless a participant has previously
elected to defer receipt of such amounts notwithstanding a Change in Control.

     In the event a participant terminates his or her employment for any reason
during a Performance Period, he or she (or his or her beneficiary, in the case
of death) will generally not be entitled to receive an Performance Award for
such Performance Period unless the Compensation Committee, in its sole and
absolute discretion, elects to pay a Performance Award to such participant. In
the event of the death of a participant, any payments due to such participant
will continue to be paid to his or her beneficiary or, failing such designation,
to his or her estate.

     The Board of Directors, or a committee designated by the Board of
Directors, may, at any time, terminate or, from time to time, amend, modify or
suspend the Annual Incentive Plan and the terms and provisions of any
Performance Award theretofore awarded to any participant which has not been
settled (either by payment or deferral). No Performance Award may be granted
during any suspension of the Plan or after its termination. Any such amendment
may be made without stockholder approval.

     The Annual Incentive Plan will constitute an "unfunded" plan for incentive
and deferred compensation. Under the terms of the plan, a participant has only
rights which are no greater than those of a general creditor of the Company.
Assuming the presence of a quorum, the affirmative vote of the holders of a
majority of all the shares of the Company's common stock present in person or by
proxy at the Annual Meeting is required for adoption of the proposal concerning
the Annual Incentive Plan. The Annual Incentive Plan permits the Compensation
Committee to authorize the creation of trusts and deposit therein cash or other
property or make other arrangements, to meet the Company's obligations under the
Annual Incentive Plan.

     The Annual Incentive Plan became effective on January 1, 2003, subject to
the approval of the stockholders at the Annual Meeting.

     New Plan Benefits.  The amounts payable under the Annual Incentive Plan for
2003 which may be received by each of (a) the executive officers of the Company
named in the Summary Compensation Table above; (b) the executive officers of the
Company as a group; and (c) Company employees who are not executive officers as
a group, is not currently determinable .

     THE BOARD RECOMMENDS A VOTE "FOR" THE APPROVAL OF THE ANNUAL INCENTIVE PLAN
(PROPOSAL NO. 3 ON YOUR PROXY CARD).

                                        41


                                 PROPOSAL NO. 4
            RATIFICATION OF INDEPENDENT CERTIFIED PUBLIC ACCOUNTANTS

     The Audit Committee has selected KPMG LLP as the Company's independent
certified public accountants for the year ending December 31, 2003. KPMG LLP has
served as the Company's auditor since 1988. The selection of independent
certified public accountants is to be voted upon at the meeting, and it is
intended that the persons named in the accompanying proxy will vote for KPMG
LLP. Representatives of KPMG LLP are expected to attend the meeting, to have an
opportunity to make a statement if they desire to do so and to be available to
respond to appropriate questions.

     THE BOARD RECOMMENDS A VOTE "FOR" THE SELECTION OF KPMG LLP TO ACT AS THE
COMPANY'S INDEPENDENT CERTIFIED PUBLIC ACCOUNTANTS FOR THE YEAR ENDING DECEMBER
31, 2003 (PROPOSAL NO. 4 ON YOUR PROXY CARD).

                             STOCKHOLDER PROPOSALS

     A stockholder proposal intended to be presented at the Company's Annual
Meeting of Stockholders to be held in 2004 must be received by the Company on or
before January 1, 2004 in order to be included in the Company's proxy statement
and form of proxy relating to that meeting. In addition, the Company's By-laws
provide that any stockholder wishing to present a proposal or to nominate a
candidate for Director at an annual meeting must give notice to the Secretary of
the Company not less than 60 nor more than 90 days prior to the date of the
meeting. If, however, the date of the meeting is first publicly announced or
disclosed (in a public filing or otherwise) less than 70 days prior to the date
of the meeting, such advance notice shall be given not more than ten days after
such date is first announced or disclosed. You may obtain a copy of the
Company's By-laws by writing to the Secretary of the Company at the address
shown on the cover of this proxy statement.

                                 OTHER MATTERS

     The Board of Directors does not know of any matters, other than those
referred to in this proxy statement, to be presented at the meeting for action
by the stockholders. However, if any other matters are properly brought before
the meeting or any postponements or adjournments thereof, it is intended that
votes will be cast with respect to such matters, pursuant to the proxies, in
accordance with the recommendations of the Board of Directors or, if no
recommendation is given, in the discretion of the person acting under the
proxies.

                                          By Order of the Board of Directors

                                          /s/ Michael J. Howerton
                                          Michael J. Howerton
                                          Secretary

New York, New York
August 21, 2003

     IT IS IMPORTANT THAT PROXIES BE RETURNED PROMPTLY. NO MATTER HOW LARGE OR
SMALL YOUR HOLDINGS MAY BE, WE URGE YOU TO FILL IN, SIGN AND RETURN THE
ACCOMPANYING PROXY CARD OR FOLLOW THE PROCEDURES OUTLINED ON THE PROXY CARD TO
VOTE BY TELEPHONE OR VIA THE INTERNET.

                                        42


                                                                      APPENDIX A

                          IMCLONE SYSTEMS INCORPORATED

            CHARTER OF THE AUDIT COMMITTEE OF THE BOARD OF DIRECTORS

                            ADOPTED AUGUST 14, 2003

     I.  Composition of the Committee

     The Audit Committee (the "Committee") of the Board of Directors (the
"Board") of the Company shall be comprised of at least three directors, each of
whom (i) shall be "independent" under the rules of the Nasdaq Stock Market, Inc.
and the Sarbanes-Oxley Act of 2002 (the "2002 Act"), (ii) does not accept,
directly or indirectly, any consulting, advisory or other compensatory fee from
the Company other than in his or her capacity as a member of the Board or any
committee of the Board, and (iii) is not an affiliate of the Company and does
not own or control 10% or more of the Company's voting securities, or such lower
measurement as may be established by the Securities and Exchange Commission (the
"SEC"). All members of the Committee must be able to read and understand
fundamental financial statements, including a company's balance sheet, income
statement, and cash flow statement, and the Committee shall have at least one
member who is an Audit Committee "financial expert", as defined by the SEC for
purposes of the 2002 Act.

     No director may serve as a member of the Committee if such director serves
on the audit committees of more than two other public companies unless the Board
of Directors determines that such service would not impair the ability of such
director to effectively serve on the Committee, and discloses this determination
in the Company's annual proxy statement. No member of the Committee may receive
any compensation from the Company other than (i) director's fees, which may be
received in cash, stock options or other in-kind consideration ordinarily
available to directors; (ii) a pension or other deferred compensation for prior
service that is not contingent on future service; and (iii) any other regular
benefits that other directors receive.

     Committee members shall be appointed by the Board annually and may be
removed by the Board at any time. The Board shall designate the chairperson of
the Committee.

     II.  Purposes of the Committee

     The purposes of the Committee are to:

          1.  assist Board oversight of (i) the integrity of the Company's
     financial statements, (ii) the Company's procedures and processes for
     compliance with legal and regulatory requirements, (iii) the independent
     auditors' qualifications and independence, and (iv) the performance of the
     independent auditors and the Company's internal audit function; and

          2.  prepare the required report pursuant to the rules of the SEC for
     inclusion in the Company's annual proxy statement.

     The function of the Committee is oversight. The management of the Company
is responsible for the preparation, presentation and integrity of the Company's
financial statements. Management and the internal auditing department are
responsible for applying and maintaining appropriate accounting and financial
reporting principles, policies and internal controls and procedures to meet the
objective of compliance with accounting standards and applicable laws and
regulations. The independent auditors are responsible for planning and carrying
out a complete, accurate and timely audit of the Company's annual financial
statements and review of the Company's quarterly Form 10-Q financial statements
prior to the filing of such quarterly report and other procedures. In fulfilling
their responsibilities hereunder, it is recognized that members of the Committee
are not full-time employees of the Company and are not, and do not represent
themselves to be, performing the functions of auditors or accountants. As such,
it is not the duty or responsibility of the Committee or its members to conduct
"field work" or other types of auditing or accounting reviews or procedures or
to set auditor independence standards.

                                       A-1


     The independent auditors for the Company are accountable to the Board and
the Committee, as representatives of the stockholders. The Committee is directly
responsible for the appointment, compensation and oversight of the work of the
independent auditors (including resolving disagreements between management and
the auditors regarding financial reporting). The Committee has the authority and
responsibility to appoint (subject to stockholder ratification), retain, oversee
and terminate the Company's independent auditors. The Company's independent
auditors shall report directly to the Committee.

     The independent auditors shall submit to the Committee annually a formal
written statement (the "Auditors' Statement") describing: (i) the auditors'
internal quality-control procedures; (ii) any material issues raised by the most
recent internal quality-control review or peer review of the auditors, or by any
inquiry or investigation by governmental or professional authorities within the
preceding five years respecting one or more independent audits carried out by
the auditors, and any steps taken to deal with any such issues; and (iii) in
order to assess the auditors' independence all relationships between the
independent auditors and the Company, including each non-audit service provided
to the Company and the matters set forth in Independence Standards Board No. 1.

     The independent auditors shall submit to the Committee annually a formal
written statement of the fees billed for audit services, audit-related services,
tax services and all other services.

     III.  Meetings of the Committee

     The Committee shall meet in person or telephonically at least quarterly and
in addition at the discretion of Chairman or upon the request of a majority of
the members, or upon unanimous written consent as determined by the Committee or
its chairperson. The chairperson shall set meeting agendas. In addition, the
Committee shall meet once every fiscal quarter, or more frequently if
circumstances dictate, to discuss with management the annual audited financial
statements and quarterly financial statements, as applicable. The Committee
should meet separately periodically with management, including those responsible
for finance, control, and legal matters, the head of the internal auditing
department and the independent auditors to discuss any matters (such as the
adequacy and proper, timely functioning of the Company's control, reporting and
compliance systems or procedures) that the Committee or any of these persons or
firms believe should be discussed privately. The Committee may request any
officer or employee of the Company or the Company's outside counsel or
independent auditors to attend a meeting of the Committee or to meet with any
members of, or consultants to, the Committee. Members of the Committee may
participate in a meeting of the Committee by means of conference call or similar
communications equipment by means of which all persons participating in the
meeting can hear each other.

     IV.  Duties and Powers of the Committee

     To carry out its purposes, the Committee shall have the following duties
and powers:

          1.  with respect to the independent auditors,

             (i) to appoint (subject to stockholder ratification), retain,
        oversee and terminate the independent auditors including sole authority
        to approve all audit engagement fees and terms;

             (ii) to pre-approve all audit services, audit-related services, tax
        services and all other services to be provided by the independent
        auditors, which approval process shall include consideration of whether
        such non-audit services are compatible with maintaining the independence
        of the outside auditors;

             (iii) to ensure that the independent auditors prepare and deliver
        annually an Auditors' Statement (it being understood that the
        independent auditors are responsible for the accuracy and completeness
        of this Statement), and to discuss with the independent auditors any
        relationships or services disclosed in the Auditors' Statement that may
        impact the quality of audit services or the objectivity and independence
        of the Company's independent auditors;

             (iv) to obtain from the independent auditors in connection with any
        audit a timely report relating to the Company's annual audited financial
        statements describing all critical accounting

                                       A-2


        policies and practices used, all alternative treatments for policies and
        practices related to material items within generally accepted accounting
        principles that have been discussed with management, ramifications of
        the use of such alternative disclosures and treatments, and the
        treatment preferred by the independent auditors, and any material
        written communications between the independent auditors and management,
        such as any "management" letter or schedule of unadjusted differences;

             (v) to review and evaluate the qualifications, performance and
        independence of the lead partner or partners of the independent
        auditors;

             (vi) to discuss the timing and process for the rotation of the lead
        audit partner and the reviewing partner, which must occur every five
        years;

             (vii) to take into account the opinions of management and the
        Company's internal auditors, if any, in assessing the independent
        auditors' qualifications, performance and independence; and

             (viii) to instruct the independent auditors that the independent
        auditors are ultimately accountable to the Board and the Committee, as
        representatives of the stockholders.

          2.  with respect to the internal auditing department,

             (i) to review annually the appointment and replacement of the head
        of the internal auditing department;

             (ii) to instruct the head of the internal auditing department that
        he or she is expected to provide to the Committee summaries of and, as
        appropriate, any significant reports to management prepared by the
        internal auditing department and management's responses thereto; and

             (iii) to review responsibilities, projects and staffing of the
        internal auditing department.

          3.  with respect to financial reporting principles and policies and
        internal audit controls and procedures,

             (i) to advise management, the internal auditing department and the
        independent auditors that they are expected to provide to the Committee
        a timely analysis of significant financial reporting issues and
        practices, including new developments, policies, or requirements
        applicable to the Company;

             (ii) to consider any reports or communications (and management's
        and/or the internal audit department's responses thereto) submitted to
        the Committee by the independent auditors required by or referred to in
        SAS 61 (as codified by AU Section 380), as it may be modified or
        supplemented, including reports and communications related to:

           - deficiencies noted in the audit in the design or operation of
             internal controls;

           - consideration of fraud in a financial statement audit or otherwise;

           - detection of illegal acts;

           - the independent auditors' responsibility under generally accepted
             auditing standards;

           - any restriction on audit scope;

           - significant accounting policies adopted or employed;

           - any communications discussed with the independent auditors'
             national office respecting auditing or accounting issues presented
             by the engagement;

           - management judgments and accounting estimates;

           - any accounting adjustments arising from the audit that were noted
             or proposed by the independent auditors but were passed (as
             immaterial or otherwise);

                                       A-3


           - the responsibility of the independent auditors for other
             information in documents containing audited financial statements;

           - disagreements with management;

           - consultation by management with other accountants;

           - major issues discussed with management prior to retention of the
             independent auditors;

           - difficulties encountered with management in performing the audit;

           - the independent auditors' judgments about the quality of the
             Company's accounting principles;

           - reviews of interim financial information conducted by the
             independent auditors; and

           - the responsibilities, budget and staffing of the Company's internal
             audit function;

             (iii) to meet with management, the independent auditors and, as
        appropriate, the head of the internal auditing department:

           - to review all related party transactions of the Company;

           - to discuss the scope of the annual audit;

           - to discuss the annual audited financial statements and quarterly
             financial statements, including the Company's disclosures under
             "Management's Discussion and Analysis of Financial Condition and
             Results of Operations";

           - to discuss any significant matters arising from any audit,
             including any audit problems or difficulties, whether raised by
             management, the internal auditing department or the independent
             auditors, relating to the Company's financial statements;

           - to discuss any difficulties the independent auditors encountered in
             the course of the audit, including any restrictions on their
             activities or access to requested information and any significant
             disagreements with management;

           - to discuss any "management" or "internal control" letter issued, or
             proposed to be issued, by the independent auditors to the Company;

           - to review the form of opinion the independent auditors propose to
             render to the Board and stockholders; and

           - to discuss, as appropriate: (a) any major issues regarding
             accounting principles and financial statement presentations,
             including any significant changes in the Company's selection or
             application of accounting principles, and major issues as to the
             adequacy of the Company's internal controls and any special audit
             steps adopted in light of material control deficiencies; (b)
             analyses prepared by management, the independent auditors and/or
             the head of the internal auditing department setting forth
             significant financial reporting issues and judgments made in
             connection with the preparation of the financial statements,
             including analyses of the effects of alternative GAAP methods on
             the financial statements; and (c) the effect of regulatory and
             accounting initiatives, as well as off-balance sheet structures, on
             the financial statements of the Company;

           - to review the management and general counsel representation letters
             to the independent auditors;

             (iv) to inquire of the Company's chief executive officer, chief
        financial officer, controller, vice president internal audit, general
        counsel and any others it may select as to the existence of any
        significant deficiencies in the design or operation of internal controls
        that could adversely affect the Company's ability to record, process,
        summarize and report financial data, any material weaknesses

                                       A-4


        in internal controls, and any fraud, whether or not material, that
        involves management or other employees;

             (v) to discuss guidelines and policies governing the process by
        which senior management of the Company and the relevant departments of
        the Company assess and manage the Company's major financial risk
        exposures and the steps management has taken to monitor and control such
        exposures;

             (vi) to obtain from the independent auditors assurance that the
        audit was conducted in a manner consistent with Section 10A of the
        Securities Exchange Act of 1934, as amended, which sets forth certain
        procedures to be followed in any audit of financial statements required
        under the Securities Exchange Act of 1934;

             (vii) to review and discuss with the Company's general counsel,
        chief executive officer and chief financial officer any significant
        legal, compliance or regulatory matters that may have a material effect
        on the financial statements or the Company's business, financial
        statements or compliance policies, including material notices to or
        inquiries received from governmental agencies and any letters received
        from outside law firms discussing such significant legal issues,
        threatened or otherwise;

             (viii) to review and discuss earnings press releases prior to being
        made public;

             (ix) to discuss the types of financial information and earnings
        guidance provided, if any, and the types of presentations made, to
        security analysts, portfolio managers, investment bankers (unless an
        appropriate confidentiality agreement is in effect) and debt rating
        agencies;

             (x) to establish procedures and ensure the implementation of such
        procedures for the receipt, retention and treatment of complaints or
        suggestions received by the Company regarding accounting, internal
        accounting controls or auditing matters, and for the confidential,
        anonymous submission by Company employees of concerns regarding
        questionable accounting or auditing matters and to review any
        significant complaints or suggestions regarding material accounting,
        internal accounting controls or auditing matters received pursuant to
        such procedures; and

             (xi) to establish hiring policies for employees or former employees
        of the independent auditors, which policies shall provide that no former
        employee of the independent auditors may become the chief executive
        officer, controller, chief financial officer or chief accounting officer
        (or serve in a similar capacity) if such person participated in any
        capacity in the Company's audit within the one-year period preceding the
        date of initiation of the audit.

        4.  with respect to reporting and recommendations,

             (i) to prepare any report or other disclosure, including any
        recommendation of the Committee, required by the rules of the SEC to be
        included in the Company's annual proxy statement;

             (ii) to review and reassess the adequacy of this Charter at least
        annually and recommend any changes to the full Board;

             (iii) to report its activities to the full Board on a regular basis
        and to make such recommendations with respect to the above and other
        matters as the Committee may deem necessary or appropriate; and

             (iv) to prepare and review with the Board an annual performance
        evaluation of the Committee, which evaluation must compare the
        performance of the Committee with the requirements of this Charter and
        which evaluation shall be conducted in such manner as the Committee
        deems appropriate. The report to the Board may take the form of an oral
        report by the chairperson of the Committee or any other member of the
        Committee designated by the Committee to make this report.

                                       A-5


     V.  Delegation to Subcommittee

     The Committee may, in its discretion, delegate all or a portion of its
duties and responsibilities to a subcommittee of the Committee. The Committee
may, in its discretion, delegate to one or more of its members the authority to
pre-approve any audit or non-audit services to be performed by the independent
auditors, provided that any such approvals are presented to the Committee for
ratification at its next scheduled meeting.

     VI.  Resources and Authority of the Committee

     The Committee shall have the resources and authority appropriate to
discharge its duties and responsibilities, including the authority to select,
retain, terminate, and approve the fees and other retention terms of special or
independent counsel, accountants or other experts and advisors, as it deems
necessary or appropriate, without seeking approval of the Board or management.
The Audit Committee shall notify the Board of any such action.

                                       A-6


                                                                      APPENDIX B

                          IMCLONE SYSTEMS INCORPORATED

                             2002 STOCK OPTION PLAN

     1.  Purpose.  The purpose of the ImClone Systems Incorporated 2002 Stock
Option Plan (the "Plan") is to enhance the ability of ImClone Systems
Incorporated (the "Company") and its Subsidiaries to attract and retain
officers, employees, directors and consultants of outstanding ability and to
provide officers, employees, directors and consultants with an interest in the
Company parallel to that of the Company's shareholders. The term "Company" as
used in this Plan with reference to employment or service shall include the
Company and its Subsidiaries, as appropriate.

     2.  Definitions.

     (a) "Board" shall mean the Board of Directors of the Company.

     (b) "Cause" shall mean (i) if a Participant is party to an employment
agreement or similar agreement with the Company and such agreement includes a
definition of Cause, the definition contained therein or (ii) if no such
employment or similar agreement exists, it shall mean (A) the Participant's
failure to substantially perform the duties reasonably assigned to him or her by
the Company, which has not been cured by the Participant following 10 days prior
written notice from the Company, (B) a good faith finding by the Company of the
Participant's dishonesty, gross negligence or misconduct, (C) a material breach
by the Participant of any written Company employment policies or rules or (D)
the Participant's conviction for, or his or her plea of guilty or nolo
contendere to, a felony or for any other crime which involves fraud, dishonesty
or moral turpitude.

     (c) "Change in Control" of the Company means the occurrence of one of the
following events:

          (i) individuals who, on the Effective Date, constitute the Board (the
     "Incumbent Directors") cease for any reason to constitute at least a
     majority of the Board, provided that any person becoming a director
     subsequent to the Effective Date whose election or nomination for election
     was approved by a vote of at least two-thirds of the Incumbent Directors
     then on the Board (either by a specific vote or by approval of the proxy
     statement of the Company in which such person is named as a nominee for
     director, without objection to such nomination) shall be an Incumbent
     Director; provided, however, that no individual initially elected or
     nominated as a director of the Company as a result of an actual or
     threatened election contest with respect to directors or as a result of any
     other actual or threatened solicitation of proxies by or on behalf of any
     person other than the Board shall be an Incumbent Director;

          (ii) any "person" (as such term is defined in Section 3(a)(9) of the
     Securities Exchange Act of 1934 (the "Exchange Act") and as used in
     Sections 13(d)(3) and 14(d)(2) of the Exchange Act) is or becomes, after
     the Effective Date, a "beneficial owner" (as defined in Rule 13d-3 under
     the Exchange Act), directly or indirectly, of securities of the Company
     representing 35% or more of the combined voting power of the Company's then
     outstanding securities eligible to vote for the election of the Board (the
     "Company Voting Securities"); provided, however, that an event described in
     this paragraph (ii) shall not be deemed to be a Change in Control if any of
     following becomes such a beneficial owner: (A) the Company or any
     majority-owned subsidiary (provided, that this exclusion applies solely to
     the ownership levels of the Company or the majority-owned subsidiary), (B)
     any tax-qualified, broad-based employee benefit plan sponsored or
     maintained by the Company or any majority-owned subsidiary, (C) any
     underwriter temporarily holding securities pursuant to an offering of such
     securities, or (D) any person pursuant to a Non-Qualifying Transaction (as
     defined in paragraph (iii));

          (iii) the consummation of a merger, consolidation, statutory share
     exchange or similar form of corporate transaction involving the Company or
     any of its Subsidiaries that requires the approval of the Company's
     stockholders, whether for such transaction or the issuance of securities in
     the transaction (a "Business Combination"), unless immediately following
     such Business Combination: (A) 60% or more of the total voting power of (x)
     the corporation resulting from such Business Combination (the
                                       B-1


     "Surviving Corporation"), or (y) if applicable, the ultimate parent
     corporation that directly or indirectly has beneficial ownership of 100% of
     the voting securities eligible to elect directors of the Surviving
     Corporation (the "Parent Corporation"), is represented by Company Voting
     Securities that were outstanding immediately prior to such Business
     Combination (or, if applicable, is represented by shares into which such
     Company Voting Securities were converted pursuant to such Business
     Combination), and such voting power among the holders thereof is in
     substantially the same proportion as the voting power of such Company
     Voting Securities among the holders thereof immediately prior to the
     Business Combination, (B) no person (other than any employee benefit plan
     (or related trust) sponsored or maintained by the Surviving Corporation or
     the Parent Corporation), is or becomes the beneficial owner, directly or
     indirectly, of 35% or more of the total voting power of the outstanding
     voting securities eligible to elect directors of the Parent Corporation
     (or, if there is no Parent Corporation, the Surviving Corporation) and (C)
     at least a majority of the members of the board of directors of the Parent
     Corporation (or if there is no Parent Corporation, the Surviving
     Corporation) following the consummation of the Business Combination were
     Incumbent Directors at the time of the Board's approval of the execution of
     the initial agreement providing for such Business Combination (any Business
     Combination which satisfies all of the criteria specified in (A), (B) and
     (C) above shall be deemed to be a "Non-Qualifying Transaction"); or

          (iv) stockholder approval of a liquidation or dissolution of the
     Company, unless the voting common equity interests of an ongoing entity
     (other than a liquidating trust) are beneficially owned, directly or
     indirectly, by the Company's shareholders in substantially the same
     proportions as such shareholders owned the Company's outstanding voting
     common equity interests immediately prior to such liquidation and such
     ongoing entity assumes all existing obligations of the Company under this
     Plan.

     Notwithstanding the foregoing, a Change in Control of the Company shall not
be deemed to occur solely because any person acquires beneficial ownership of
more than 35% of the Company Voting Securities as a result of the acquisition of
Company Voting Securities by the Company which reduces the number of Company
Voting Securities outstanding; provided, that, if after such acquisition by the
Company such person becomes the beneficial owner of Company Voting Securities
that increases the percentage of outstanding Company Voting Securities
beneficially owned by such person, a Change in Control of the Company shall then
occur.

     (d) "Code" shall mean the Internal Revenue Code of 1986, as amended.

     (e) "Committee" shall mean a committee of at least two members of the Board
appointed by the Board to administer the Plan and to perform the functions set
forth herein and who are "non-employee directors" within the meaning of Rule
16b-3 as promulgated under Section 16 of the Securities Exchange Act of 1934, as
amended (the "Exchange Act") and who are also "outside directors" within the
meaning of Section 162(m) of the Code.

     (f) "Common Stock" shall mean the common stock of the Company.

     (g) "Continuous Service" means that the Participant's service as an
employee, director or consultant with the Company or a Subsidiary is not
interrupted or terminated. The Participant's Continuous Service shall not be
deemed to have terminated merely because of a change in the capacity in which
the Participant renders service to the Company or a Subsidiary as an employee,
director or consultant or a change in the entity for which the Participant
renders such service; provided, that, there is no interruption or termination of
the Participant's Continuous Service other than an approved leave of absence.
The Committee, in its sole discretion, may determine whether Continuous Service
shall be considered interrupted.

     (h) "Disability" shall have the same meaning as provided in any long-term
disability plan maintained by the Company or any Subsidiary in which a
Participant then participates (the "LTD Plans"); provided, that, if no such plan
exists, it shall have the meaning set forth in Section 22(e)(3) of the Code.

     (i) "Fair Market Value" per share as of a particular date shall mean,
unless otherwise determined by the Board, the last reported sale price of the
Common Stock on the NASDAQ (or any other exchange or national

                                       B-2


market system upon which price quotations for the Company's Common Stock is
regularly available) for such date.

     (j) "Immediate Family Member" shall mean, except as otherwise determined by
the Committee, a Participant's spouse, ancestors and descendants.

     (k) "Incentive Stock Option" shall mean a stock option which is intended to
meet the requirements of Section 422 of the Code.

     (l) "Nonqualified Stock Option" shall mean a stock option which is not
intended to be an Incentive Stock Option.

     (m) "Option" shall mean either an Incentive Stock Option or a Nonqualified
Stock Option.

     (n) "Participant" shall mean anyone who is selected to participate in the
Plan in accordance with Section 5.

     (o) "Subsidiary" shall mean any affiliate of the Company selected by the
Board; provided, that, with respect to Incentive Stock Options, it shall mean
any subsidiary of the Company that is a corporation and which at the time
qualifies as a "subsidiary corporation" within the meaning of Section 424(f) of
the Code.

     (p) "Substitute Awards" shall mean Options granted or shares issued by the
Company in assumption of, or in substitution or exchange for, awards previously
granted, or the right or obligation to make future awards, by a company acquired
by the Company or with which the Company is combined.

     3.  Shares Subject to the Plan.

     (a) General. Subject to adjustment in accordance with Section 12, the total
of the number of shares of Common Stock which shall be available for the grant
of Options under the Plan shall not exceed 3,300,000 shares of Common Stock;
provided, that, for purposes of this limitation, any Common Stock subject to an
Option which is canceled, forfeited or expires prior to exercise whether such
Option was granted under this Plan or the 1998 Non-Qualified Stock Option Plan,
as amended, the 1996 Non-Qualified Stock Option Plan, as amended or the 1996
Incentive Stock Option Plan, as amended (together, the "Prior Plans") shall
again become available for grant under the Plan. In addition, any shares of
Common Stock tendered and/or withheld for the payment of all or a part of an
Option (whether granted under this Plan or the Prior Plans) or any applicable
withholding taxes shall again become available for the grant of an Option under
the Plan. The Company may, but is not required to, use the proceeds it receives
in connection with the exercise of an Option under this Plan, or under the Prior
Plans for exercises occurring after the Effective Date, to purchase shares of
its Common Stock in the open market and any such shares of Common Stock so
purchased may be used for the issuance of Options under this Plan. Substitute
Options shall not reduce the shares of Common Stock available for grants under
the Plan or to a Participant over a period of time. Subject to adjustment in
accordance with Section 12, no employee shall be granted, during any three (3)
year period, Options to purchase more than 3,300,000 shares of Common Stock.
Common Stock available for issue or distribution under the Plan shall be
authorized and unissued shares or shares reacquired by the Company in any
manner.

     (b) Incentive Stock Options. Notwithstanding Section 3(a), subject to
adjustment in accordance with Section 12, the aggregate number of shares of
Common Stock with respect to which Incentive Stock Options may be granted under
the Plan shall not exceed 825,000 shares of Common Stock. Any shares of Common
Stock subject to an Incentive Stock Option granted under this Plan or the 1996
Incentive Stock Option Plan, as amended which is canceled, forfeited or expires
prior to exercise shall again be counted toward the aggregate number of shares
available for the grant of Incentive Stock Options under this Plan.

     4.  Administration.

     (a) The Plan shall be administered by the Committee. All references to the
Committee hereinafter shall mean the Board if no such Committee has been
appointed.

     (b) The Committee shall (i) approve the selection of Participants, (ii)
determine the type of Options to be made to Participants, (iii) determine the
number of shares of Common Stock subject to Options,

                                       B-3


(iv) determine the terms and conditions of any Option granted hereunder
(including, but not limited to, any forfeiture conditions on such Option) and
(v) have the authority to interpret the Plan, to establish, amend, and rescind
any rules and regulations relating to the Plan, to determine the terms and
provisions of any agreements entered into hereunder, and to make all other
determinations necessary or advisable for the administration of the Plan. The
Committee may correct any defect, supply any omission or reconcile any
inconsistency in the Plan or in any Option in the manner and to the extent it
shall deem desirable to carry it into effect.

     (c) Any action of the Committee shall be final, conclusive and binding on
all persons, including the Company and its Subsidiaries and shareholders,
Participants and persons claiming rights from or through a Participant.

     (d) The Committee may delegate to officers or employees of the Company or
any Subsidiary, and to service providers, the authority, subject to such terms
as the Committee shall determine, to perform administrative functions with
respect to the Plan and Option awards.

     (e) Members of the Committee and any officer or employee of the Company or
any Subsidiary acting at the direction of, or on behalf of, the Committee shall
not be personally liable for any action or determination taken or made in good
faith with respect to the Plan, and shall, to the extent permitted by law, be
fully indemnified by the Company with respect to any such action or
determination.

     5.  Eligibility.  Individuals eligible to receive Options under the Plan
shall be the officers, employees, directors and consultants of the Company and
its Subsidiaries selected by the Committee; provided, that, only employees of
the Company and its Subsidiaries may be granted Incentive Stock Options.

     6.  Options.  Options may be granted under the Plan in such form as the
Committee may from time to time approve pursuant to terms set forth in an Option
award.

     (a) Types of Options. Each Option award shall state whether or not the
Option will be treated as an Incentive Stock Option or Nonqualified Stock
Option. The aggregate Fair Market Value of the Common Stock for which Incentive
Stock Options granted to any one employee under this Plan or any other incentive
stock option plan of the Company or of any of its Subsidiaries may by their
terms first become exercisable during any calendar year shall not exceed
$100,000, determining Fair Market Value as of the date each respective Option is
granted. In the event such threshold is exceeded in any calendar year, such
excess Options shall be automatically deemed to be Nonqualified Stock Options.
To the extent that any Option granted under this Plan which is intended to be an
Incentive Stock Option fails for any reason to qualify as such at any time, such
Option shall be a Nonqualified Stock Option.

     (b) Option Price. The purchase price per share of the Common Stock
purchasable under an Option shall be determined by the Committee and shall not
be less than 100% of the Fair Market Value of the Common Stock on the date of
grant. In the case of Incentive Stock Options granted to an employee owning
stock possessing more than 10% of the total combined voting power of all classes
of shares of the Company and its Subsidiaries (a "10% Shareholder") the price
per share specified in the agreement relating to such Option shall not be less
than 110% of the Fair Market Value per share of the Common Stock on the date of
grant.

     (c) Option Period. Unless otherwise provided in an Option award, the term
of each Option shall be ten (10) years from the date the Option is granted;
provided, that, in the case of Incentive Stock Options granted to 10%
Shareholders, the term of such Option shall not exceed five (5) years from the
date of grant. Notwithstanding the foregoing, unless otherwise provided in an
Option award, upon the death or Disability of a Participant, Options (other than
Incentive Stock Options) that would otherwise remain exercisable following such
death or Disability shall remain exercisable for one year following such death
or Disability notwithstanding the term of such Option.

     (d) Exercisability. Each Option shall vest and become exercisable at a rate
determined by the Committee on the date of grant.

                                       B-4


     (e) Termination of Continuous Service. Unless otherwise provided in an
Option award, any Options held by a Participant upon termination of Continuous
Service shall remain exercisable as follows:

          (i) If the Participant's termination of Continuous Service is due to
     death, all unvested Options shall automatically terminate and all vested
     Options shall be exercisable by the Participant's designated beneficiary,
     or, if none, the person(s) to whom such Participant's rights under the
     Option are transferred by will or the laws of descent and distribution for
     1 year following such termination of Continuous Service (but in no event
     beyond the term of the Option, except as provided in clause (c) above), and
     shall thereafter terminate.

          (ii) If the Participant's termination of Continuous Service is due to
     Disability, all unvested Options shall automatically terminate and all
     vested Options shall be exercisable by the Participant for 1 year following
     such Disability (but in no event beyond the term of the Option, except as
     provided in clause (c) above), and shall thereafter terminate.

          (iii) If the Participant's termination of Continuous Service is for
     Cause, the Option shall terminate upon such termination of Continuous
     Service, regardless of whether the Option was then vested and exercisable.

          (iv) If the Participant's termination of Continuous Service is for any
     other reason, all unvested Options shall terminate on the date of
     termination and all Options (to the extent exercisable as of the date of
     termination) shall be exercisable for a period of 30-days following such
     termination of employment or service (but in no event beyond the term of
     the Option), and shall thereafter terminate. The Participant's status as an
     employee shall not be considered terminated in the case of a leave of
     absence agreed to in writing by the Company (including, but not limited to,
     military and sick leave); provided, that, with respect to Incentive Stock
     Options, such leave is for a period of not more than three-months or
     re-employment upon expiration of such leave is guaranteed by contract or
     statute.

     (f) Method of Exercise. Options may be exercised, in whole or in part, by
giving written notice of exercise to the Company in a form approved by the
Company specifying the number shares of Common Stock to be purchased. Such
notice shall be accompanied by the payment in full of the Option exercise price.
Unless otherwise provided at the time of grant, the exercise price of the Option
may be paid by (i) cash or certified or bank check, (ii) surrender of Common
Stock held by the Participant for at least six (6) months prior to exercise (or
such longer or shorter period as may be required to avoid a charge to earnings
for financial accounting purposes) or the attestation of ownership of such
shares, in either case, if so permitted by the Company, (iii) through a "same
day sale" commitment from a Participant and a broker-dealer, who is reasonably
acceptable to and approved by the Company and who is a member of the National
Association of Securities Dealers, under such terms and conditions which are
reasonably acceptable to the Company, (iv) through additional methods prescribed
by the Committee, as deemed appropriate by the Committee in its discretion, or
(v) by any combination of the foregoing, and, in all instances, to the extent
permitted by applicable law. A Participant's subsequent transfer or disposition
of any Common Stock acquired upon exercise of an Option shall be subject to any
Federal and state laws then applicable, specifically securities law, and the
terms and conditions of this Plan.

     7.  Special Provisions.

     (a) Change in Control. Unless otherwise provided in an Option award, upon
the occurrence of a Change in Control, all Options and shall automatically
become vested and exercisable in full. The Committee may, in its discretion,
include such further provisions and limitations in any award documenting such
Options as it may deem equitable and in the best interests of the Company.

     (b) Forfeiture. Notwithstanding anything in the Plan to the contrary and
unless otherwise specifically provided in an Option award, in the event of a
serious breach of conduct by a Participant or former Participant (including,
without limitation, any conduct prejudicial to or in conflict with the Company
or its Subsidiary) the Committee may (i) cancel any outstanding Option granted
to such Participant or former Participant, in whole or in part, whether or not
vested, and/or (ii) if such conduct or activity occurs within one (1) year
following the exercise of an Option, require such Participant or former
Participant to repay to the Company
                                       B-5


any gain realized upon the exercise of such Option (with such gain or payment
valued as of the date of exercise). Such cancellation or repayment obligation
shall be effective as of the date specified by the Committee. Any repayment
obligation shall be satisfied in cash or, if permitted in the sole discretion of
the Committee, it may be satisfied in shares of Common Stock (based upon the
Fair Market Value of the share of Common Stock on the date of payment), and the
Committee may provide for an offset to any future payments owed by the Company
or any Subsidiary to the Participant or former Participant if necessary to
satisfy the repayment obligation. The determination of whether a Participant or
former Participant has engaged in a serious breach of conduct shall be
determined by the Committee in good faith and in its sole discretion.

     8.  Withholding.  Upon (a) disposition of shares of Common Stock acquired
pursuant to the exercise of an Incentive Stock Option granted pursuant to the
Plan within two years of the grant of the Incentive Stock Option or within one
year after exercise of the Incentive Stock Option, or (b) exercise of a
Nonqualified Stock Option (or an Incentive Stock Option treated as a
Nonqualified Stock Option), or (c) under any other circumstances determined by
the Committee in its sole discretion, the Company shall have the right to
require any Participant, and such Participant by accepting the Options granted
under the Plan agrees, to pay to the Company the amount of any taxes which the
Company shall be required to withhold with respect thereto. In the event of
clauses (a), (b) or (c), with the consent of the Committee, at its sole
discretion, such Participant may elect to have the Company withhold shares of
Common Stock having a Fair Market Value equal to the amount of the withholding
tax obligation as determined by the Company; provided, however, that no shares
of Common Stock are withheld with a value exceeding the minimum amount of tax
required to be withheld by law. Such shares so delivered to satisfy the minimum
withholding obligation may be either shares withheld by the Company upon the
exercise of the Option or other shares. At the Committee's sole discretion, a
Participant may elect to have additional taxes withheld and satisfy such
withholding with cash or shares of Common Stock held for at least six (6) months
prior to exercise, if, in the opinion of the Company's outside accountants,
doing so, would not result in a charge against earnings. If the Option is an
Incentive Stock Option, and if the Participant sells or otherwise disposes of
any of the shares acquired pursuant to the Incentive Stock Option on or before
the later of (i) the date two (2) years after the date of grant, and (ii) the
date one (1) year after transfer of such shares to the Participant upon exercise
of the Option, the Participant shall immediately notify the Company in writing
of such disposition.

     9.  Nontransferability, Beneficiaries.  Unless otherwise determined by the
Committee with respect to the transferability of Nonqualified Stock Options by a
Participant to his Immediate Family Members (or to trusts or partnerships or
limited liability companies established for such family members), no Options
shall be assignable or transferable by the Participant, otherwise than by will
or the laws of descent and distribution or pursuant to a beneficiary
designation, and Options shall be exercisable, during the Participant's
lifetime, only by the Participant (or by the Participant's legal representatives
in the event of the Participant's incapacity). Each Participant may designate a
beneficiary to exercise any Option held by the Participant at the time of the
Participant's death. If no beneficiary has been named by a deceased Participant,
any Option held by the Participant at the time of death shall be transferred as
provided in his will or by the laws of descent and distribution. Except in the
case of the holder's incapacity, an Option may only be exercised by the holder
thereof.

     10.  No Right to Continuous Service.  Nothing contained in the Plan or in
any Option under the Plan shall confer upon any Participant any right with
respect to the continuation of service with the Company or any of its
Subsidiaries, or interfere in any way with the right of the Company or its
Subsidiaries to terminate his or her Continuous Service at any time. Nothing
contained in the Plan shall confer upon any Participant or other person any
claim or right to any Option under the Plan.

     11.  Governmental Compliance.  Each Option under the Plan shall be subject
to the requirement that if at any time the Committee shall determine that the
listing, registration or qualification of any shares issuable or deliverable
thereunder upon any securities exchange or under any Federal or state law, or
the consent or approval of any governmental regulatory body, is necessary or
desirable as a condition thereof, or in connection therewith, no such Option may
be exercised or shares issued or delivered unless such listing, registration,
qualification, consent or approval shall have been effected or obtained free of
any conditions not acceptable to the Committee.
                                       B-6


     12.  Adjustments; Corporate Events.

     (a) In the event of any dividend or other distribution (whether in the form
of cash, Common Stock, other securities, or other property), recapitalization,
reclassification, stock split, reverse stock split, reorganization, merger,
consolidation, split-up, spin-off, combination, repurchase, liquidation,
dissolution, or sale, transfer, exchange or other disposition of all or
substantially all of the assets of the Company, or exchange of Common Stock or
other securities of the Company, issuance of warrants or other rights to
purchase Common Stock or other securities of the Company, or other similar
corporate transaction or event (an "Event"), and in the Committee's opinion,
such event affects the Common Stock such that an adjustment is determined by the
Committee to be appropriate in order to prevent dilution or enlargement of the
benefits or potential benefits intended to be made available under the Plan or
with respect to an Option, then the Committee shall, in such manner as it may
deem equitable, including, without limitation, adjust any or all of the
following: (i) the number and kind of shares of Common Stock (or other
securities or property) with respect to which Options may be granted; (ii) the
number and kind of shares of Common Stock (or other securities or property)
subject to outstanding Options; and (iii) the exercise price with respect to any
Option. The Committee determination under this Section 12(a) shall be final,
binding and conclusive.

     (b) Upon the occurrence of an Event in which outstanding Options are not to
be assumed or otherwise continued following such an Event, the Committee may, in
its discretion, terminate any outstanding Option (whether or not vested) without
a Participant's consent and (i) provide for either (A) the purchase of any such
Option for an amount of cash equal to the product of (I) and (II), where (I) is
equal to the number of shares of Common Stock subject to such Option and (II) is
equal to the difference between (a) the Fair Market Value of one share of Common
Stock and (b) the per share exercise price of such Option; provided, that, if
such amount would result in a negative number, the Option shall automatically
terminate and cease to be exercisable without payment for such termination or
(B) the replacement of such Option with other rights or property selected by the
Committee in its sole discretion and/or (ii) provide that such Option shall be
exercisable (whether or not vested) as to all shares covered thereby for at
least thirty (30) days prior to such Event.

     (c) The existence of the Plan, the Option awards and the Options granted
hereunder shall not affect or restrict in any way the right or power of the
Company or the shareholders of the Company to make or authorize any adjustment,
recapitalization, reorganization or other change in the Company's capital
structure or its business, any merger or consolidation of the Company, any issue
of stock or of options, warrants or rights to purchase stock or of bonds,
debentures, preferred or prior preference stocks whose rights are superior to or
affect the Common Stock or the rights thereof or which are convertible into or
exchangeable for Common Stock, or the dissolution or liquidation of the Company,
or any sale or transfer of all or any part of its assets or business, or any
other corporate act or proceeding, whether of a similar character or otherwise.

     13.  Option Awards.  Each Option under the Plan shall be evidenced by a
written document setting forth the terms and conditions, as determined by the
Committee, which shall apply to such Option, in addition to the terms and
conditions specified in the Plan.

     14.  Amendment.  The Board may amend, suspend or terminate the Plan or any
portion thereof at any time, provided that (a) no amendment shall be made
without shareholder approval if such approval is necessary to comply with any
applicable law, regulation or stock exchange rule and (b) except as provided in
Section 12, no amendment shall be made that would adversely affect the rights of
a Participant under an Option theretofore granted, without such Participant's
written consent.

     15.  General Provisions.

     (a) The Committee may require each Participant acquiring shares pursuant to
an Option under the Plan to represent to and agree with the Company in writing
that such Participant is acquiring the shares for investment and without a view
to distribution thereof.

     (b) All certificates for Common Stock delivered under the Plan pursuant to
any Option shall be subject to such stock-transfer orders and other restrictions
as the Committee may deem advisable under the rules, regulations, and other
requirements of the Securities and Exchange Commission, any stock exchange upon
                                       B-7


which the Common Stock is then listed, and any applicable Federal or state
securities law, and the Committee may cause a legend or legends to be put on any
such certificates to make appropriate reference to such restrictions. If the
Committee determines that the issuance of Common Stock hereunder is not in
compliance with, or subject to an exemption from, any applicable Federal or
state securities laws, such shares shall not be issued until such time as the
Committee determines that the issuance is permissible.

     (c) It is the intent of the Company that the Plan satisfy, and be
interpreted in a manner that satisfies, the applicable requirements of Rule
16b-3 as promulgated under Section 16 of the Exchange Act so that Participants
will be entitled to the benefit of Rule 16b-3, or any other rule promulgated
under Section 16 of the Exchange Act, and will not be subject to short-swing
liability under Section 16 of the Exchange Act. Accordingly, if the operation of
any provision of the Plan would conflict with the intent expressed in this
Section 15(c), such provision to the extent possible shall be interpreted and/or
deemed amended so as to avoid such conflict.

     (d) Except as otherwise provided by the Committee in the applicable Option
award, a Participant shall have no rights as a shareholder with respect to any
shares of Common Stocks subject to an Option until a certificate or certificates
evidencing shares of Common Stock shall have been issued to the Participant and,
subject to Section 12, no adjustment shall be made for dividends or
distributions or other rights in respect of any share for which the record date
is prior to the date on which Participant shall become the holder of record
thereof.

     (e) The law of the State of Delaware shall apply to all Options and
interpretations under the Plan regardless of the effect of such state's conflict
of laws principles.

     (f) Where the context requires, words in any gender shall include any other
gender.

     (g) Headings of Sections are inserted for convenience and reference; they
do not constitute any part of this plan.

     16.  Expiration of the Plan.  Subject to earlier termination pursuant to
Section 14, the Plan shall have an indefinite term; provided, that, the ability
to grant Incentive Stock Options will terminate on April 3, 2012 which is the
tenth (10th) anniversary of the date on which the Board adopted the Plan.

     17.  Effective Date; Approval of Shareholders.  The Plan is effective as of
the date it is approved by the affirmative vote of the holders of a majority of
the securities of the Company present, or represented, and entitled to vote at a
meeting of stockholders duly held in accordance with the applicable laws of the
State of Delaware (the "Effective Date"). If the Plan is approved, no further
grants shall be made under the terms of the Prior Plans on or after the
Effective Date; provided, that, any outstanding Options made thereunder shall be
governed and controlled by the terms and conditions of such Prior Plans and any
Option awards evidencing such Options.

                                       B-8


                                                                      APPENDIX C

                          IMCLONE SYSTEMS INCORPORATED

                             ANNUAL INCENTIVE PLAN

     1.  Purposes.  The purposes of this Plan are to provide an incentive to
executive officers and other selected key executives of the Company to
contribute to the growth, profitability and increased shareholder value of the
Company, to retain such executives and endeavor to qualify the compensation paid
under the Plan for tax deductibility under Section 162(m) of the Code.

     2.  Definitions.  For purposes of the Plan, the following terms shall be
defined as set forth below:

          (a) "Award" shall mean a Performance Award.

          (b) "Board" shall mean the Company's Board of Directors.

          (c) "Change in Control" shall mean the occurrence of one of the
     following events:

             (i) individuals who, on the Effective Date, constitute the Board
        (the "Incumbent Directors") cease for any reason to constitute at least
        a majority of the Board, provided that any person becoming a director
        subsequent to the Effective Date whose election or nomination for
        election was approved by a vote of at least two-thirds of the Incumbent
        Directors then on the Board (either by a specific vote or by approval of
        the proxy statement of the Company in which such person is named as a
        nominee for director, without objection to such nomination) shall be an
        Incumbent Director; provided, however, that no individual initially
        elected or nominated as a director of the Company as a result of an
        actual or threatened election contest with respect to directors or as a
        result of any other actual or threatened solicitation of proxies by or
        on behalf of any person other than the Board shall be an Incumbent
        Director;

             (ii) any "person" (as such term is defined in Section 3(a)(9) of
        the Securities Exchange Act of 1934 (the "Exchange Act") and as used in
        Sections 13(d)(3) and 14(d)(2) of the Exchange Act) is or becomes, after
        the Effective Date, a "beneficial owner" (as defined in Rule 13d-3 under
        the Exchange Act), directly or indirectly, of securities of the Company
        representing 35% or more of the combined voting power of the Company's
        then outstanding securities eligible to vote for the election of the
        Board (the "Company Voting Securities"); provided, however, that an
        event described in this paragraph (ii) shall not be deemed to be a
        Change in Control if any of following becomes such a beneficial owner:
        (A) the Company or any majority-owned subsidiary (provided, that this
        exclusion applies solely to the ownership levels of the Company or the
        majority-owned subsidiary), (B) any tax-qualified, broad-based employee
        benefit plan sponsored or maintained by the Company or any
        majority-owned subsidiary, (C) any underwriter temporarily holding
        securities pursuant to an offering of such securities, or (D) any person
        pursuant to a Non-Qualifying Transaction (as defined in paragraph
        (iii)).

             (iii) the consummation of a merger, consolidation, statutory share
        exchange or similar form of corporate transaction involving the Company
        or any of its subsidiaries that requires the approval of the Company's
        stockholders, whether for such transaction or the issuance of securities
        in the transaction (a "Business Combination"), unless immediately
        following such Business Combination: (A) 60% or more of the total voting
        power of (x) the corporation resulting from such Business Combination
        (the "Surviving Corporation"), or (y) if applicable, the ultimate parent
        corporation that directly or indirectly has beneficial ownership of 100%
        of the voting securities eligible to elect directors of the Surviving
        Corporation (the "Parent Corporation"), is represented by Company Voting
        Securities that were outstanding immediately prior to such Business
        Combination (or, if applicable, is represented by shares into which such
        Company Voting Securities were converted pursuant to such Business
        Combination), and such voting power among the holders thereof is in
        substantially the same proportion as the voting power of such Company
        Voting Securities among the holders thereof immediately prior to the
        Business Combination, (B) no person (other than any
                                       C-1


        employee benefit plan (or related trust) sponsored or maintained by the
        Surviving Corporation or the Parent Corporation), is or becomes the
        beneficial owner, directly or indirectly, of 35% or more of the total
        voting power of the outstanding voting securities eligible to elect
        directors of the Parent Corporation (or, if there is no Parent
        Corporation, the Surviving Corporation) and (C) at least a majority of
        the members of the board of directors of the Parent Corporation (or if
        there is no Parent Corporation, the Surviving Corporation) following the
        consummation of the Business Combination were Incumbent Directors at the
        time of the Board's approval of the execution of the initial agreement
        providing for such Business Combination (any Business Combination which
        satisfies all of the criteria specified in (A), (B) and (C) above shall
        be deemed to be a "Non-Qualifying Transaction"); or

             (iv) Stockholder approval of a liquidation or dissolution of the
        Company, unless the voting common equity interests of an ongoing entity
        (other than a liquidating trust) are beneficially owned, directly or
        indirectly, by the Company's shareholders in substantially the same
        proportions as such shareholders owned the Company's outstanding voting
        common equity interests immediately prior to such liquidation and such
        ongoing entity assumes all existing obligations of the Company to
        Executive under this Agreement.

        Notwithstanding the foregoing, a Change in Control of the Company shall
        not be deemed to occur solely because any person acquires beneficial
        ownership of more than 35% of the Company Voting Securities as a result
        of the acquisition of Company Voting Securities by the Company which
        reduces the number of Company Voting Securities outstanding; provided,
        that, if after such acquisition by the Company such person becomes the
        beneficial owner of Company Voting Securities that increases the
        percentage of outstanding Company Voting Securities beneficially owned
        by such person, a Change in Control of the Company shall then occur.

          (e) "Code" shall mean the Internal Revenue Code of 1986, as amended
     from time to time, including regulations thereunder and successor
     provisions thereto.

          (f) "Committee" shall mean a committee composed of at least two
     members of the Board who qualify as "outside directors" within the meaning
     of Section 162(m) of the Code.

          (g) "Company" shall mean ImClone Systems, Inc. and any entity that
     succeeds to all or substantially all of its business.

          (h) "Effective Date" shall mean January 1, 2003.

          (i) "Eligible Employee" shall mean each executive officer of the
     Company, including those employed by subsidiaries, and other key executives
     of the Company selected by the Committee.

          (j) "GAAP" shall mean U.S. Generally Accepted Accounting Principles.

          (k) "Participant" shall mean an Eligible Employee designated by the
     Committee to participate in the Plan for a designated Performance Period.

          (l) "Performance Award" shall mean the right of a Participant to
     receive cash or other property following the completion of a Performance
     Period based upon performance in respect of one or more of the Performance
     Goals during such Performance Period, as specified in Section 5.

          (m) "Performance Goals" shall mean or may be expressed in terms of any
     of the following business criteria: revenue, earnings before interest,
     taxes, depreciation and amortization ("EBITDA"), funds from operations,
     funds from operations per share, operating income (loss), pre or after tax
     income (loss), cash available for distribution, cash available for
     distribution per share, cash and/or cash equivalents available for
     operations, net earnings (loss), earnings (loss) per share, return on
     equity, return on assets, share price performance, improvements in the
     Company's attainment of expense levels, implementing or completion of
     critical projects, including, without limitation, implementation of
     strategic plan(s), improvement in investor relations, marketing and
     manufacturing of key products, improvement in cash-flow (before or after
     tax), development of critical projects or product development, or progress
     relating to

                                       C-2


     research and development. A Performance Goal may be measured over a
     Performance Period on a periodic, annual, cumulative or average basis and
     may be established on a corporate-wide basis or established with respect to
     one or more operating units, divisions, subsidiaries, acquired businesses,
     minority investments, partnerships or joint ventures. Unless otherwise
     determined by the Committee by no later than the earlier of the date that
     is ninety days after the commencement of the Performance Period or the day
     prior to the date on which twenty-five percent of the Performance Period
     has elapsed, the Performance Goals will be determined by not accounting for
     a change in GAAP during a Performance Period.

          (n) "Performance Objective" shall mean the level or levels of
     performance required to be attained with respect to specified Performance
     Goals in order that a Participant shall become entitled to specified rights
     in connection with a Performance Award.

          (o) "Performance Period" shall mean the calendar year, or such other
     shorter or longer period designated by the Committee, during which
     performance will be measured in order to determine a Participant's
     entitlement to receive payment of an Award.

          (p) "Plan" shall mean this ImClone Systems Incorporated Annual
     Incentive Plan, as amended from time to time.

     3.  Administration.

     (a) Authority.  The Plan shall be administered by the Committee. The
Committee is authorized, subject to the provisions of the Plan, in its sole
discretion, from time to time to select Participants; to grant Awards under the
Plan; to determine the type, terms and conditions of, and all other matters
relating to, Awards; to prescribe Award agreements (which need not be
identical); to establish, modify or rescind such rules and regulations as it
deems necessary for the proper administration of the Plan; and to make such
determinations and interpretations and to take such steps in connection with the
Plan or the Awards granted thereunder as it deems necessary or advisable. All
such actions by the Committee under the Plan or with respect to the Awards
granted thereunder shall be final and binding on all persons.

     (b) Manner of Exercise of Committee Authority.  The Committee may delegate
its responsibility with respect to the administration of the Plan to one or more
officers of the Company, to one or more members of the Committee or to one or
more members of the Board; provided, however, that the Committee may not
delegate its responsibility (i) to make Awards to executive officers of the
Company; (ii) to make Awards which are intended to constitute "qualified
performance-based compensation" under Section 162(m) of the Code; or (iii) to
certify the satisfaction of Performance Objectives pursuant to Section 5(e) in
accordance with Section 162(m) of the Code. The Committee may also appoint
agents to assist in the day-to-day administration of the Plan and may delegate
the authority to execute documents under the Plan to one or more members of the
Committee or to one or more officers of the Company.

     (c) Limitation of Liability.  The Committee may appoint agents to assist it
in administering the Plan. The Committee and each member thereof shall be
entitled to, in good faith, rely or act upon any report or other information
furnished to him or her by any officer or employee of the Company, the Company's
independent certified public accountants, consultants or any other agent
assisting in the administration of the Plan. Members of the Committee and any
officer or employee of the Company acting at the direction or on behalf of the
Committee shall not be personally liable for any action or determination taken
or made in good faith with respect to the Plan, and shall, to the extent
permitted by law, be fully indemnified and protected by the Company with respect
to any such action or determination.

     4.  Types of Awards.  Subject to the provisions of the Plan, the Committee
has the discretion to grant to Participants Performance Awards described in
Section 5.

     5.  Performance Awards.

     (a) Form of Award.  The Committee is authorized to grant Performance Awards
pursuant to this Section 5. A Performance Award shall represent the conditional
right of the Participant to receive cash or other property based upon
achievement of one or more pre-established Performance Objectives during a
                                       C-3


Performance Period, subject to the terms of this Section 5 and the other
applicable terms of the Plan. Performance Awards shall be subject to such
conditions, including deferral of settlement, risks of forfeiture, restrictions
on transferability and other terms and conditions as shall be specified by the
Committee.

     (b) Performance Objectives.  The Committee shall establish the Performance
Objective for each Performance Award, consisting of one or more business
criteria permitted as Performance Goals hereunder, one or more levels of
performance with respect to each such criteria, and the amount or amounts
payable or other rights that the Participant will be entitled to upon
achievement of such levels of performance. The Performance Objective shall be
established by the Committee prior to, or reasonably promptly following the
inception of, a Performance Period but, to the extent required by Section 162(m)
of the Code, by no later than the earlier of the date that is ninety days after
the commencement of the Performance Period or the day prior to the date on which
twenty-five percent of the Performance Period has elapsed.

     (c) Additional Provisions Applicable to Performance Awards.  More than one
Performance Goal may be incorporated in a Performance Objective, in which case
achievement with respect to each Performance Goal may be assessed individually
or in combination with each other. The Committee may, in connection with the
establishment of Performance Objectives for a Performance Period, establish a
matrix setting forth the relationship between performance on two or more
Performance Goals and the amount of the Performance Award payable for that
Performance Period. The level or levels of performance specified with respect to
a Performance Goal may be established in absolute terms, as objectives relative
to performance in prior periods, as an objective compared to the performance of
one or more comparable companies or an index covering multiple companies, or
otherwise as the Committee may determine. Performance Objectives shall be
objective and shall otherwise meet the requirements of Section 162(m) of the
Code. Performance Objectives may differ for Performance Awards granted to any
one Participant or to different Participants.

     (d) Duration of the Performance Period.  The Committee shall establish the
duration of each Performance Period at the time that it sets the Performance
Objectives applicable to that Performance Period. The Committee shall be
authorized to permit overlapping or consecutive Performance Periods.

     (e) Certification.  Following the completion of each Performance Period,
the Committee shall certify in writing, in accordance with the requirements of
Section 162(m) of the Code, whether the Performance Objective and other material
terms for paying amounts in respect of each Performance Award related to that
Performance Period have been achieved or met. Unless the Committee determines
otherwise, Performance Awards shall not be settled until the Committee has made
the certification specified under this Section 5(e).

     (f) Adjustment.  The Committee is authorized at any time during or after a
Performance Period to reduce or eliminate the Performance Award of any
Participant for any reason, including, without limitations changes in the
position or duties of any Participant with the Company during or after a
Performance Period, whether due to any termination of employment (including
death, disability, retirement, voluntary termination or termination with or
without cause) or otherwise. In addition, to the extent necessary to preserve
the intended economic effects of the Plan to the Company and the Participants,
the Committee shall adjust Performance Objectives, the Performance Awards or
both to take into account: (i) a change in corporate capitalization, (ii) a
corporate transaction, such as any merger of the Company or any subsidiary into
another corporation, any consolidation of the Company or any subsidiary into
another corporation, any separation of the Company or any subsidiary (including
a spinoff or the distribution of stock or property of the Company or any
subsidiary), any reorganization of the Company or any subsidiary or a large,
special and non-recurring dividend paid or distributed by the Company (whether
or not such reorganization comes within the definition of Section 368 of the
Code), (iii) any partial or complete liquidation of the Company or any
subsidiary or (iv) a change in accounting or other relevant rules or regulations
(any adjustment pursuant to this Clause (iv) shall be subject to the timing
requirements of the last sentence of Section 2(m) of the Plan); provided,
however, that no adjustment hereunder shall be authorized or made if and to the
extent that the Committee determines that such authority or the making of such
adjustment would cause the Performance Awards to fail to qualify as "qualified
performance-based compensation" under Section 162(m) of the Code.

     (g) Timing of Payment.  Except as provided below, any cash amounts payable
in respect of Performance Awards for a Performance Period will generally be paid
as soon as practicable following the
                                       C-4


determination in respect thereof made pursuant to Section 5(e), and any non-cash
amounts or any other rights that the Participant is entitled to with respect to
a Performance Award for a Performance Period will be paid or vest in accordance
with the terms of the Performance Award.

     (h) Deferral of Payments.  Subject to such terms, conditions and
administrative guidelines as the Committee shall specify from time to time, a
Participant shall have the right to elect to defer receipt of part or all of any
payment due with respect to a Performance Award.

     (i) Maximum Amount Payable Per Participant Under This Section 5.  With
respect to Performance Awards to be settled in cash or property, a Participant
shall not be granted Performance Awards for all of the Performance Periods
commencing in a calendar year that permit the Participant in the aggregate to
earn a cash payment or payment in other property, in excess of $2,000,000.

     (j) Change In Control.  In the event of a Change in Control, any incomplete
Performance Periods applicable to Performance Awards under this Section 5 in
effect on the date the Change in Control occurs shall end on the date of such
change, and the Committee shall (i) determine the extent to which the
Performance Objectives with respect to such Performance Periods shall have been
met based on such audited or unaudited financial information then available as
it deems necessary, and (ii) cause to be paid to each Participant partial or
full Performance Awards with respect to the Performance Periods based on the
Committee's determination of the degree of attainment of the Performance
Objectives. Notwithstanding Section 5(f), in the event of a Change in Control,
the Committee shall not be authorized to reduce or eliminate the Performance
Award; provided, that, a Participant's Performance Award to which he or she
would otherwise be entitled shall be multiplied by a fraction, the numerator of
which is the number of days in the Performance Period prior to the Change in
Control and the denominator of which is the total number of days in the
Performance Period as originally specified. Any resulting amount hereunder due
to a Participant shall be paid in a cash lump sum no later than fifteen days
after a Change in Control, unless the Participant has previously elected to
defer receipt of such amounts notwithstanding a Change in Control.

     6.  General Provisions.

     (a) Termination of Employment.  In the event a Participant terminates
employment for any reason during a Performance Period or prior to the Award
payment, he or she (or his or her beneficiary, in the case of death) shall not
be entitled to receive any Award for such Performance Period unless the
Committee, in its sole and absolute discretion, elects to pay an Award to such
Participant.

     (b) Death of the Participant.  Subject to Section 6(a), in the event of the
death of a Participant, any payments hereunder due to such Participant shall be
paid to his or her beneficiary as designated in writing to the Committee or,
failing such designation, to his or her estate. No beneficiary designation shall
be effective unless it is in writing and received by the Committee prior to the
date of death of the Participant.

     (c) Taxes.  The Company is authorized to withhold from any Award granted,
any payment relating to an Award under the Plan, or any payroll or other payment
to a Participant, amounts of withholding and other taxes due in connection with
any transaction involving an Award, and to take such other action as the
Committee may deem advisable to enable the Company and Participants to satisfy
obligations for the payment of withholding taxes and other tax obligations
relating to any Award. This authority shall include authority for the Company to
withhold or receive other property and to make cash payments in respect thereof
in satisfaction of a Participant's tax obligations, either on a mandatory or
elective basis in the discretion of the Committee.

     (d) Limitations on Rights Conferred under Plan and Beneficiaries.  Neither
status as a Participant nor receipt or completion of a deferral election form
shall be construed as a commitment that any Award will become payable under the
Plan. Nothing contained in the Plan or in any documents related to the Plan or
to any Award shall confer upon any Eligible Employee or Participant any right to
continue as an Eligible Employee, Participant or in the employ of the Company or
constitute any contract or agreement of employment, or interfere in any way with
the right of the Company to reduce such person's compensation, to change the
position held by such person or to terminate the employment of such Eligible
Employee or Participant, with or without cause, but nothing contained in this
Plan or any document related thereto shall
                                       C-5


affect any other contractual right of any Eligible Employee or Participant. No
benefit payable under, or interest in, this Plan shall be transferable by a
Participant except by will or the laws of descent and distribution or otherwise
be subject in any manner to anticipation, alienation, sale, transfer,
assignment, pledge, encumbrance or charge.

     (e) Changes to the Plan and Awards.  Notwithstanding anything herein to the
contrary, other than Section 5(j), the Board, or a committee designated by the
Board, may, at any time, terminate or, from time to time, amend, modify or
suspend the Plan and the terms and provisions of any Award theretofore granted
to any Participant which has not been settled (either by payment or deferral).
No Award may be granted during any suspension of the Plan or after its
termination. Any such amendment may be made without stockholder approval.

     (f) Unfunded Status of Awards; Creation of Trusts.  The Plan is intended to
constitute an "unfunded" plan for incentive and deferred compensation. With
respect to any amounts payable to a Participant pursuant to an Award, nothing
contained in the Plan (or in any documents related thereto), nor the creation or
adoption of the Plan, the grant of any Award, or the taking of any other action
pursuant to the Plan shall give any such Participant any rights that are greater
than those of a general creditor of the Company; provided, that, the Committee
may authorize the creation of trusts and deposit therein cash or other property
or make other arrangements, to meet the Company's obligations under the Plan.
Such trusts or other arrangements shall be consistent with the "unfunded" status
of the Plan unless the Committee otherwise determines with the consent of each
affected Participant. The trustee of such trusts may be authorized to dispose of
trust assets and reinvest the proceeds in alternative investments, subject to
such terms and conditions as the Committee may specify in accordance with
applicable law.

     (g) Non-Exclusivity of the Plan.  Neither the adoption of the Plan by the
Board (or a committee designated by the Board) nor submission of the Plan or
provisions thereof to the stockholders of the Company for approval shall be
construed as creating any limitations on the power of the Board to adopt such
other incentive arrangements as it may deem necessary.

     (h) Governing Law.  The validity, construction, and effect of the Plan, any
rules and regulations relating to the Plan, and any Award shall be determined in
accordance with the laws of the State of New York, without giving effect to
principles of conflicts of laws, and applicable Federal law.

     (i) Exemption Under Section 162(m) of the Code.  The Plan, and all Awards
issued thereunder, are intended to be exempt from the application of Section
162(m) of the Code, which restricts under certain circumstances the Federal
income tax deduction for compensation paid by a public company to named
executives in excess of $1 million per year. The Committee may, without
stockholder approval, amend the Plan retroactively or prospectively to the
extent it determines necessary in order to comply with any subsequent
clarification of Section 162(m) of the Code required to preserve the Company's
Federal income tax deduction for compensation paid pursuant to the Plan.

     (j) Effective Date.  The Plan is effective on the Effective Date, subject
to subsequent approval thereof by the Company's stockholders at the first annual
meeting of stockholders to occur after the Effective Date, and shall remain in
effect until it has been terminated pursuant to Section 6(e). If the Plan is not
approved by the stockholders at such annual meeting, the Plan and all interests
in the Plan awarded to Participants before the date of such annual meeting shall
be void ab initio and of no further force and effect. Unless the Company
determines to submit Section 5 of the Plan and the definition of "Performance
Goal" to the Company's stockholders at the first stockholder meeting that occurs
in the fifth year following the year in which the Plan was last approved by
stockholders (or any earlier meeting designated by the Board), in accordance
with the requirements of Section 162(m) of the Code, and such stockholder
approval is obtained, then no further Performance Awards shall be made under
Section 5 after the date of such annual meeting.

                                       C-6


                          IMCLONE SYSTEMS INCORPORATED

Dear Stockholder,

     Please take note of the important information enclosed with this Proxy
Ballot. There are a number of issues related to the management and operations of
your Company that require your immediate attention and approval. These are
discussed in detail in the enclosed proxy materials.

     Your vote counts, and you are strongly encouraged to exercise your right to
vote your shares.

     Please mark the boxes on the proxy card to indicate how your shares should
be voted. Then sign the card, detach it and return your proxy vote in the
enclosed postage paid envelope. You may also vote your shares by telephone or
via the Internet. If you choose to vote by telephone or via the Internet, you do
not need to return the attached card.

     Your vote must be received prior to the Annual Meeting of Stockholders,
September 15, 2003.

     Thank you in advance for your prompt consideration of these matters.

                                          Sincerely,

                                          IMCLONE SYSTEMS INCORPORATED

                          IMCLONE SYSTEMS INCORPORATED

Dear Stockholder:

Please take note of the important information enclosed with this Proxy Ballot.
There are a number of issues related to the management and operation of your
Company that require your immediate attention and approval. These are discussed
in detail in the enclosed proxy materials.

Your vote counts, and you are strongly encouraged to exercise your right to vote
your shares.

Please mark the boxes on this proxy card to indicate how your shares will be
voted. Then sign the card, detach it and return your proxy vote in the enclosed
postage paid envelope. You may also vote your shares by telephone or via the
Internet. If you choose to vote by telephone or via the Internet, do not return
your proxy card by mail.

Your vote must be received prior to the Annual Meeting of Stockholders,
September 15, 2003.

Thank you in advance for your prompt consideration of these matters.

Sincerely,

ImClone Systems Incorporated



                                  DETACH HERE                             ZIMLC2

                          IMCLONE SYSTEMS INCORPORATED

           PROXY FOR THE MEETING OF STOCKHOLDERS, SEPTEMBER 15, 2003
          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

The undersigned hereby appoints Michael J Howerton, David M. Kies and Daniel S.
Lynch as Proxies, each with power of substitution, and hereby authorizes each of
them to represent and to vote, as designated below, all the shares of common
stock of ImClone Systems Incorporated held of record by the undersigned on
August 20, 2003 at the Annual Meeting of Stockholders to be held at 10:00 a.m.
on September 15, 2003 or any postponements or adjournments thereof.

PLEASE MARK, DATE, SIGN AND RETURN THIS PROXY TO EQUISERVE, THE COMPANY'S
TRANSFER AGENT, TO BE RECEIVED NO LATER THAN SEPTEMBER 14, 2003.

THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY
THE UNDERSIGNED STOCKHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED
FOR PROPOSALS 1, 2, 3 AND 4.

   IF YOU CHOOSE TO VOTE BY MAIL, PLEASE MARK, DATE, AND SIGN ON REVERSE SIDE
                 AND RETURN PROMPTLY IN THE ENCLOSED ENVELOPE.

HAS YOUR ADDRESS CHANGED?                 DO YOU HAVE ANY COMMENTS?

- -------------------------------------     --------------------------------------

- -------------------------------------     --------------------------------------

- -------------------------------------     --------------------------------------

IMCLONE SYSTEMS INCORPORATED
C/O EQUISERVE TRUST COMPANY N.A.
P.O. BOX 8694
EDISON, NJ 08818-8694

                              VOTER CONTROL NUMBER

                YOUR VOTE IS IMPORTANT. PLEASE VOTE IMMEDIATELY.

VOTE-BY-INTERNET [COMPUTER LOGO]

1.    LOG ON TO THE INTERNET AND GO TO HTTP://WWW.EPROXYVOTE.COM/IMCL


2.    ENTER YOUR VOTER CONTROL NUMBER LISTED ABOVE AND FOLLOW THE EASY STEPS
      OUTLINED ON THE SECURED WEBSITE.

OR

VOTE-BY-TELEPHONE [TELEPHONE LOGO]

1.    CALL TOLL-FREE
      1-877-PRX-VOTE (1-877-779-8683)

2.    ENTER YOUR VOTER CONTROL NUMBER LISTED ABOVE AND FOLLOW THE EASY RECORDED
      INSTRUCTIONS.


  IF YOU VOTE OVER THE INTERNET OR BY TELEPHONE, PLEASE DO NOT MAIL YOUR CARD.

            DETACH HERE IF YOU ARE RETURNING YOUR PROXY CARD BY MAIL      ZIMLC1


[X] PLEASE MARK
    VOTES AS IN
    THIS EXAMPLE.

IMCLONE SYSTEMS INCORPORATED

1.    Election of Directors.

      NOMINEES: (01) Andrew G. Bodnar, (02) Vincent T. DeVita, Jr., (03) John A.
      Fazio, (04) David M. Kies and (05) William R. Miller.


  FOR      [ ]                 [ ]    WITHHELD
  ALL                                 FROM ALL
NOMINEES                              NOMINEES

[ ]
   ------------------------------------------
   For all nominee(s) except as written above



                                                                                    FOR      AGAINST     ABSTAIN
                                                                                                
2.    Approval of an amendment to the ImClone Systems Incorporated 2002 Stock       [ ]        [ ]         [ ]
      Option Plan (the "2002 Option Plan") to increase the number of shares
      authorized to be issued under the 2002 Option Plan.

3.    Approval of the ImClone Systems Incorporated Annual Incentive Plan.           [ ]        [ ]         [ ]


4.    Ratification of the appointment of KPMG LLP to serve as the Company's         [ ]        [ ]         [ ]
      independent certified public accountants for the fiscal year ending
      December 31, 2003.

5.    Any other business as may come before the meeting or any postponements or
      adjournments thereof.

      Mark box at right if you plan to attend the meeting.                          [ ]

      Mark box at right if an address change or comment has been noted              [ ]
      on the reverse side of this card.


      NOTE: Please sign exactly as name(s) appear(s) on the books of the
      Company. Joint owners should each sign personally. When signing as
      executor, administrator, attorney, trustee or guardian or as custodian for
      a minor, please give full title as such. If a corporation, please sign in
      full corporate name and indicate the signer's office. If a partner, sign
      the partnership name.

Please be sure to sign and date this Proxy.

Signature:                                          Date:
          -----------------------------------------      -----------------------

Signature:                                          Date:
          -----------------------------------------      -----------------------