EXHIBIT 32.1

                               CAMBREX CORPORATION
     CERTIFICATION PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
                            (18 U.S.C. SECTION 1350)


Pursuant to the requirements of Section 906 of the Sarbanes-Oxley Act of 2002
(18 U.S.C. Sections 1350 (a) and (b)), the undersigned hereby certify as
follows:

      1.    John R. Leone is the President and Chief Executive Officer of
            Cambrex Corporation.

      2.    The Company's Form 10-Q/A for the quarterly period ended September
            30, 2004, accompanying this Certification, in the form filed with
            the Securities and Exchange Commission (the "Report") fully complies
            with the requirements of Section 13(a) or 15(d) of the Securities
            Exchange Act of 1934 (the "Exchange Act") and

      3.    The information in the Report fairly presents, in all material
            respects, the financial condition and results of operation of the
            Company.

Dated: April 29, 2005

                                       /s/ John R. Leone
                                       ------------------------------
                                       John R. Leone, President
                                       and Chief Executive Officer

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