Exhibit 99.906CERT SECTION 906 CERTIFICATION Pursuant to 18 U.S.C. Section 1350, the undersigned officer of Wells Fargo Master Trust (the "Trust"), hereby certifies, to the best of her knowledge, that the Trust's report on Form N-CSRS for the period ended August 31, 2010 (the "Report") fully complies with the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934 and that the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Trust. Date: October 29, 2010 By: /s/ Karla M. Rabusch Karla M. Rabusch President Wells Fargo Master Trust Exhibit 99.906CERT SECTION 906 CERTIFICATION Pursuant to 18 U.S.C. Section 1350, the undersigned officer of Wells Fargo Master Trust (the "Trust"), hereby certifies, to the best of his knowledge, that the Trust's report on Form N-CSRS for the period ended August 31, 2010 (the "Report") fully complies with the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934 and that the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Trust. Date: October 29, 2010 By: /s/ Kasey L. Phillips Kasey L. Phillips Treasurer Wells Fargo Master Trust