1

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.

                                                              September 23, 1997


                             (1) GLAXO GROUP LIMITED

                                       and

                           (2) CHIREX (ANNAN) LIMITED


                   ------------------------------------------

                                    AGREEMENT

                        for the sale and purchase of the
                   Business and Assets of Glaxo Group Limited
                        operated from its site at Annan,
                               Dumfries, Scotland

                   ------------------------------------------
   2

                                      INDEX

CLAUSE

1.   DEFINITIONS AND INTERPRETATION..........................................  1

2.   SALE AND PURCHASE OF BUSINESS AND ASSETS................................ 12

3.   PURCHASE PRICE.......................................................... 13

4.   CONDITIONS.............................................................. 13

5.   PERIOD BEFORE COMPLETION................................................ 16

6.   COMPLETION.............................................................. 17

7.   REIMBURSEMENT OF COSTS.................................................. 19

8.   COMPLETION STATEMENT.................................................... 20

9.   CONTRACTS............................................................... 21

10.  CREDITORS AND LIABILITIES............................................... 22

11.  EMPLOYEES............................................................... 26

12.  PENSIONS................................................................ 28

13.  APPORTIONMENT........................................................... 28

14.  WARRANTIES.............................................................. 29

15.  RIGHT TO RESCIND........................................................ 31

16.  POST COMPLETION OBLIGATIONS............................................. 32

17.  VALUE ADDED TAX......................................................... 34

18.  CAPITAL GOODS SCHEME.................................................... 35

19.  FURTHER ASSURANCE....................................................... 35

20.  DISPUTE RESOLUTION...................................................... 36

21.  SECONDMENT.............................................................. 37
   3

22.  ANNOUNCEMENTS........................................................... 38

23.  COSTS................................................................... 38

24.  SUCCESSORS AND ASSIGNMENT............................................... 38

25.  ENTIRE AGREEMENT........................................................ 38

26.  TIME OF THE ESSENCE..................................................... 39

27.  NOTICES................................................................. 39

28.  AGREEMENT CONTINUES IN FORCE............................................ 39

29.  SEVERABILITY............................................................ 39

30.  WAIVER.................................................................. 40

31.  VARIATIONS.............................................................. 40

32.  COUNTERPARTS............................................................ 40

33.  FUNDING................................................................. 40

34.  GOVERNING LAW........................................................... 40


SCHEDULE 1................................................................... 42
     Apportionment of Purchase Price......................................... 42

SCHEDULE 2................................................................... 44
     The Property............................................................ 44

SCHEDULE 3................................................................... 48
     Terms and Conditions of Sale of the Property............................ 48

SCHEDULE 4................................................................... 53
     Pensions................................................................ 53

     Definitions............................................................. 53

     Calculation of the Transfer Requirement................................. 59

     Payment of the Transfer Requirement and Provision of
     Benefits................................................................ 60

     Additional Voluntary Contributions...................................... 63
   4

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


SCHEDULE 5................................................................... 67
     Warranties.............................................................. 67

SCHEDULE 6...................................................................103
     Limitations to Vendor's Liability.......................................103
   5

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


Agreed Form documents*


Annexures*
   6

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


*These documents have been omitted from the filing because the Registrant does
not believe them material to an investment in its Common Stock. The documents
will be furnished supplementally to the Commission upon request.
   7

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.

THIS AGREEMENT is made September 23, 1997

BETWEEN:

(1)   GLAXO GROUP LIMITED (registered number 305979) whose registered office is
      at Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex UB6 0NN
      (the "Vendor"),

(2)   CHIREX (ANNAN) LIMITED (registered number 3417229) whose registered office
      is at Dudley, Cramlington, Northumberland NE23 7QG (the "Purchaser")

WHEREAS

The Vendor carries on the Business and the Vendor has agreed to sell and the
Purchaser has agreed to purchase the Business and the Assets as a going concern
for the consideration and otherwise upon the terms and conditions set out in
this agreement.

IT IS HEREBY AGREED:

1.    DEFINITIONS AND INTERPRETATION

      1.1   In this agreement the following words and expressions shall (except
            where the context otherwise requires) have the following meanings:

            "Access Agreement" means the access agreement between Dumfries and
            Galloway Regional Council and a company within the Vendor's Group
            dated 8 June 1979 and 17 July 1979 and recorded in the Division of
            the General Register of Sasines applicable to the County of Dumfries
            on 21 September 1979;

            "Accounts" means the audited financial statements of the Annan
            manufacturing site of GWO for each of the three consecutive
            accounting reference periods ended on 31 December 1994, 31 December
            1995 and 31 December 1996 respectively and the audited financial
            statements of the Annan manufacturing site of GWO for the period
            from 31 December 1996 to 


                                       1
   8

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            Completion and the financial statements to be produced pursuant to
            clause 16.2;

            "Accounts Date" means the date as at which the Accounts were
            respectively prepared;

            "Assets" means, the Contracts, the Equipment, the Fixed Plant, the
            Goodwill, the Intellectual Property, the Property, the Stock and the
            Work in Progress; 

            "Body Corporate" means any body corporate other than a company
            incorporated under the Companies Acts;

            "Business" means the business of the manufacture and sale of
            pharmaceutical intermediates carried on at the date hereof at the
            Property by the Vendor;

            "Business Day" means a day other than a Saturday or Sunday on which
            banks are open for business in London;

            "Cash" means the cash in hand and at bank of the Vendor in respect
            of the Business at the Completion Date;

            "Companies Acts" means the 1985 Act and the 1989 Act;

            "Company" means (i) for the purposes of paragraph 1.3.1 of Schedule
            3 a company incorporated under the Companies Acts and/or a Friendly
            Society and/or an Industrial and Provident Society and/or a foreign
            company and (ii) for the purposes of paragraphs 1.3.2 and 1.3.4 of
            Schedule 3, a company incorporated under the Companies Acts;

            "Completion" means completion of the sale and purchase of the Assets
            in accordance with Clause 6;

            "Completion Date" means 5 pm on the date on which Completion takes
            place;


                                       2
   9

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            "Computer Systems" means the computer systems used by or for the
            benefit of the Business and which are located on the Property or
            computer processors associated and peripheral equipment computer
            programs, technical and other documentation and data entered into or
            created by the Vendor and used by or for the benefit of the Business
            from time to time;

            "Conditions" means the conditions contained or referred to in Clause
            4;

            "Confidential Information" means information concerning or relating
            to property owned or used in connection with the Business in the
            nature of know-how, trade secrets, technical processes, and any
            other matters concerning the business, affairs or finances of the
            Business (however stored) (details of which are not in the public
            domain);

            "Contracts"

            (i) means those contracts entered into by or on behalf of the Vendor
            in connection with the Business for the purchase of raw materials
            and intermediates by the Vendor details of which are set out in the
            list in agreed terms headed "Purchase Contracts";

            (ii) means such other written contracts (but excluding the Lease
            Contracts) entered into by or on behalf of the Vendor in connection
            with the Business details of which are set out in the list in agreed
            terms headed "Other Contracts";

            and in each case which shall be subsisting but uncompleted (both
            those part performed and those not yet commenced) on the Completion
            Date;

            "Deeds and Documents" means those deeds and documents relating to
            the Property identified in the list in agreed terms headed "Deeds
            and Documents";


                                       3
   10

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            "Defective" means cannot be used for its intended purpose in its
            current form or used to produce good quality material without undue
            expense being incurred in relation to it;

            "Disclosed Scheme(s)" means the retirement benefits schemes details
            of which are set out in Schedule 4 Part 1;

            "Disclosure Letter" means the letter of even date with this
            agreement from the Vendor to the Purchaser in agreed terms relating
            to the Warranties together with any documents annexed thereto;

            "Disposition" means a Disposition of the Property with absolute
            warrandice in the form annexed hereto (Annex 6) to be granted by GWO
            to the Purchaser on Completion;

            "Employees" means those employees of the Vendor whose employment is
            to be transferred to the Purchaser and whose names and details of
            employment are set out in the list in agreed terms headed
            "Employees";

            "Employment Letter" a letter from the Vendor to the Purchaser
            relating to the Employees;

            "Encumbrance" means a mortgage, equity, charge, lien, claim, third
            party right standard security, floating charge or other encumbrance;

            "Environment" means all or any of the following media namely: the
            air (including without limitation the air within buildings and the
            air within other natural or manmade structures above or below
            ground), water and land and any living organisms or systems
            supported by those media;

            "Environmental Laws" means all European Community or Union
            Regulations, directives and statutory decisions, all statutes and
            subordinate legislation, 


                                       4
   11

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            all regulations, orders and ordinances including but without
            limitation the Environment Act 1995, the Radioactive Substances Act
            1993, the Planning (Hazardous Substances) (Scotland) Act 1997, the
            Control of Pollution Act 1974, and the Environment Act 1990 and the
            Sewerage (Scotland) Act 1968 together with Part IIA Environmental
            Protection Act 1990, Sections 161A - 161D Water Resources Act 1991
            and Sections 46A-D of the Control of Pollution Act 1974 the Private
            Water Supply (Scotland) Regulations and all subordinate legislation
            or guidance having effect thereunder and all consents, permits,
            authorizations and local laws and bye-laws, all judgments, decrees,
            orders, instructions, demands or awards of any competent authority
            in each of the foregoing cases which are directly applicable in the
            United Kingdom or any parts thereof and which concern the protection
            of the Environment;

            "Equipment" means all the loose plant, equipment, engineering
            supplies, machinery, tools, motor vehicles, furniture, trade
            utensils and other chattels owned or used in connection with the
            Business at the Completion Date located at the Property (or which
            are leased or hired under the terms of any of the Lease Contracts)
            including but without limitation those items set out in the list in
            agreed terms headed "Equipment";

            "Excluded Assets" means the items listed at Schedule 1 Part 2;

            "Excluded Employees" means those employees of the Vendor (previously
            employed within the Business) whose employment is not to be
            transferred to the Purchaser hereunder details of whom are set out
            in the list in agreed terms headed "Excluded Employees";

            "External Costs" means the external costs including labour costs
            incurred by the Vendor directly in connection with the design and
            development works 


                                       5
   12

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            which the Purchaser agrees or has agreed is necessary at the
            Property to facilitate the production of ****;

            "Finished Products" means any products manufactured by the Vendor or
            any member of the Vendor's Group in connection with the Business;

            "Fixed Plant" means the fixed plant owned or used in connection with
            the Business and physically attached to the Property including,
            without limitation, that identified in the list in agreed terms
            headed "Fixed Plant";

            "Foreign Company" means any legal person, other than a natural
            person, incorporated elsewhere than in Great Britain;

            "Glaxo Wellcome plc Letter" means a letter in agreed terms from
            Glaxo Wellcome plc relating to the transfer of the Employees";

            "Grazing Lease" means the grazing lease entered into between a
            company within the Vendor's Group and Messrs J.M. & J. Goldie dated
            3 March 1997;

            "Goodwill" means the goodwill of the Business excluding any part
            thereof which is an Excluded Asset;

            "GWO" means Glaxo Operations UK Limited (registered number 711851)
            which trades under the name Glaxo Wellcome Operations;

            "Hoddam" means Hoddam Contracting Company Limited having its
            registered office at Hoddam Road, Ecclefechan;

            "Hoddam Agreement" means the agreement for the supply of water to
            Hoddam constituted by letter dated 14 January 1997 from GWO to
            Hoddam and 


                                       6
   13

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            Hoddam's endorsed acceptance thereof dated 4 February 1997;

            "Information Technology Services Agreement" means the agreement in
            agreed terms between GWO and the Purchaser relating to the provision
            of information technology support by GWO to the Purchaser;

            "Intellectual Property" means patents, inventions, know-how, trade
            secrets and other confidential information, registered designs,
            copyrights, design rights, rights affording equivalent protection to
            copyright and design rights, topography rights, trade marks, service
            marks, business names, trade names, moral rights, registration of an
            application to register any of the aforesaid items, rights in the
            nature of any of the aforesaid items in any country, rights in the
            nature of unfair competition rights and rights to sue for
            passing-off in all such cases relating exclusively to the Business
            but excluding any of the foregoing which relates to any Excluded
            Asset;

            "IPC Authorization" means the Integrated Pollution Control
            Authorizations issued in respect of the Business under Section 6 of
            the Environmental Protection Act 1990 being authorization number
            IPC/063/1994, IPC/011/1994, IPC/012/1994; and IPC/058/93;

            "Keeper" means the Keeper of the Registers of Scotland;

            "Land Register" means the Land Register of Scotland;

            "Last Actuarial Valuation" means the last actuarial valuation or
            funding review of the Disclosed Scheme received (whether in draft or
            final form) prior to the date of this agreement;

            "Lease Contracts" means the lease and hire purchase agreements
            entered into by or on behalf of GWO in 


                                       7
   14

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            connection with the Business and subsisting at the Completion Date
            details of which are set out in the list in agreed terms headed
            "Lease Contracts";

            "Management Accounts" means the unaudited balance sheet and profit
            and loss account of the Annan manufacturing site of GWO for the
            monthly periods ending respectively 31 July 1997, 31 August 1997,
            and 30 September 1997;

            "Obsolete" means cannot be used for the purpose intended in
            connection with the Business;

            "Parties" means the parties to this agreement;

            "Pensions Warranties" means the warranties contained in Schedule 4
            Part 3;

            "Pipeline" means the pipeline for the supply of water from the River
            Annan to within the Property and all pumps, valves, manholes,
            inspection chambers and associated plant and equipment and
            apparatus, the right to part of which is governed by the Servitudes
            and the weir in the River Annan immediately downstream from the
            Pumphouse, the line of the Pipeline being shown on the plan annexed
            to this agreement headed "Plan A" (Annex 1) including without
            prejudice to the generality the Pumphouse and the Pumping Station;

            "Property" means the heritable property and servitude rights
            described in Schedule 2 and any parts thereof;

            "Pumphouse" means the pumphouse, pump and intake pipe and other
            plant and equipment constructed on the subjects described (In the
            Third Place) (FIRST) in Schedule 2;

            "Pumping Station" means the pumping station and pumps and other
            equipment constructed on the 


                                       8
   15

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            subjects described (In the Third Place) (SECOND) in Schedule 2;

            "Purchase Price" means the aggregate amount payable by the Purchaser
            for the Business and the Assets as set out in Clause 3;

            "Purchaser's Accountants" means Arthur Andersen of Pearl Assurance
            House, 7 New Bridge Street, Newcastle Upon Tyne NE1 8BQ;

            "Purchaser's Group" means the Purchaser, any parent company of the
            Purchaser and any company which, in relation to the Purchaser and/or
            any parent company of the Purchaser, is a subsidiary undertaking
            from time to time;

            "Purchaser's Property Solicitors" means Brodies of 15 Atholl
            Crescent, Edinburgh EH3 8HA;

            "Purchaser's Solicitors" means Dibb Lupton Alsop of 117 The Headrow,
            Leeds LS1 5JX;

            "Records" means a list of all suppliers, books and records, whether
            stored on hard copy or on computer and computer programmes, designs,
            drawings, plans and specifications and other technical matter in
            relation to the Business together with any plates, blocks, negatives
            and other like material relating thereto other than the Retained
            Records and other than any of the foregoing which relate to Excluded
            Assets;

            "Regulations" means the Transfer of Undertakings (Protection of
            Employment) Regulations 1981 as amended by the Collective
            Redundancies and Transfer of Undertakings (Protection of Employment)
            Amendment Regulations 1995;

            "Relevant Claim" means any claim by the Purchaser relating to a
            breach of the Warranties;


                                       9
   16

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            "Retained Records" means those records of or relating to the
            Business details of which are set out in the list is agreed terms
            headed "Retained Records";

            "Secondment Letter" means the letter in agreed terms between GWO and
            the Purchaser relating to the secondment of certain of the Employees
            by the Purchaser to a Vendor Group Company;

            "SEPA" means the Scottish Environmental Protection Agency;

            "Secrecy Agreement" means the secrecy agreement between Glaxo
            Wellcome plc and Chirex Limited dated 30 May 1997 entered into in
            contemplation of the sale of the Business and Assets under this
            agreement;

            "Servitudes" shall have the meaning given in Schedule 2;

            "SSAP" and "FRS"" means respectively a Statement of Standard
            Accounting Practice or Financial Reporting Standard in force at this
            date as made or adopted by the Accounting Standards Board Limited;

            "Shelf-Life" means the period during which intermediates and raw
            materials may properly be used;

            "Stock" means the stock in trade of unfinished goods, intermediates,
            raw materials, fuel, of the Vendor for the purposes of the Business
            as at the Completion Date (including items which although supplied
            to the Vendor under reservation of title by the suppliers are under
            the control of the Vendor);

            "Subjects" shall have the meaning given in Schedule 2;


                                       10
   17

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            "subscribed" means in relation to any document, that such document
            is validly subscribed so that the document shall be presumed to have
            been subscribed by the grantor of it for the purposes of Sections 3
            and/or 7 of, and/or Schedule 2 to, the Requirements of Writing
            (Scotland) Act 1995;

            "Supply Agreement" means the agreement in agreed terms between GWO
            and the Purchaser relating to the supply of products by the
            Purchaser to GWO;

            "Tax" means all forms of taxation, duty, levy, charges, and
            withholdings, or social security contribution and any fine, penalty,
            or interest in respect thereof;

            "Taxes Act" means the Income and Corporation Taxes Act 1988;

            "VAT" means Value Added Tax;

            "Vendor's Accountants" means Coopers & Lybrand of Plumtree Court
            London;

            "Vendor's Group" means the Vendor, any parent company of the Vendor
            and any company which, in relation to the Vendor and/or any parent
            company of the Vendor is a subsidiary undertaking from time to time;

            "Warranties" means the representations, warranties and undertakings
            on the Vendor's part contained or referred to in Clause 14 and
            Schedule 5 and including the Pensions Warranties;

            "Water Abstraction Consents" means the consents to the abstraction
            of water from the River Annan which are detailed in the assignation
            thereof the form of which is annexed hereto (Annex 2);


                                       11
   18

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            "Water Supply" means the taking of water from the River Annan by the
            Pipeline;

            "Work in Progress" means work in process of the Vendor for the
            purposes of the Business as at the Completion Date ;

            "1979 Act" means the Land Registration (Scotland) Act 1979;

            "1985 Act" means the Companies Act 1985; and

            "1989 Act" means the Companies Act 1989.

      1.2   Any reference in this agreement to any provision of any Act of
            Parliament shall include reference to any subordinate legislation
            (as defined in the Interpretation Act 1978) made pursuant thereto
            and shall be deemed (unless otherwise expressly provided) to be a
            reference to such Act of Parliament or subordinate legislation as
            amended, modified or re-enacted (whether before or after the date
            hereof) and any reference to any provision of any such Act of
            Parliament or subordinate legislation shall also include where
            appropriate any provision of which it is a re-enactment (whether
            with or without modification).

      1.3   In this agreement words incorporating the masculine gender only
            include the feminine and neuter genders and words incorporating the
            singular number only include the plural and vice versa.

      1.4   Unless otherwise stated references to Clauses, sub-clauses and
            Schedules are references to Clauses and sub-clauses of and Schedules
            to this agreement. The Schedules form part of this agreement.


                                       12
   19

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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


      1.5   The Index and clause headings are for ease of reference only and do
            not affect the construction or interpretation of this agreement.

      1.6   References to persons shall include bodies corporate, unincorporated
            associations and partnerships.

      1.7   References to the parties hereto include their respective successors
            in title, assigns and legal personal representatives.

      1.8   A body corporate shall be deemed to be associated with another body
            corporate if it is a holding company of, or a subsidiary of, or a
            subsidiary of a holding company of, that other body corporate and a
            person shall be deemed to be connected with another if that person
            is so connected within the meaning of Section 839 of the Taxes Act.

      1.9   Where a document is referred to in this agreement as being "in
            agreed terms", it shall be in the form agreed by the parties to this
            agreement and initialed by or on behalf of them for identification.

      1.10  Where any statement is qualified by the expression "to the best of
            the knowledge information and belief of the Vendor" or "so far as
            the Vendor is aware" or any similar expression there shall be deemed
            to be included after such statement the words "after careful
            consideration and having made appropriate enquiry of relevant
            persons currently in the employment of any company in the Vendor
            Group and the following professional advisers; Sackers, the Vendor's
            Accountants, Dundas & Wilson and the knowledge of the Vendor shall
            be deemed to include the knowledge of each of the companies within
            the Vendor's Group.


                                       13
   20

Portions of this Exhibit have been omitted pursuant to a request for
confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


2.    SALE AND PURCHASE OF BUSINESS AND ASSETS

      2.1   The Vendor shall sell with full title guarantee (save for the
            Property)and the Purchaser shall purchase the Business as a going
            concern and all of the Assets free from all Encumbrances as at the
            Completion Date.

      2.2   The Property shall be transferred in accordance with the terms and
            subject to the conditions set out in Schedule 3.

      2.3   There shall be excluded from the sale and purchase hereby agreed
            upon the Excluded Assets and nothing herein contained shall operate
            so as to impose upon the Purchaser any obligations or liabilities in
            respect of any other assets or liabilities of the Vendor except as
            specifically provided in this agreement.

3.    PURCHASE PRICE

      3.1   The Purchase Price payable by the Purchaser for the Business and the
            Assets shall be the aggregate of:

            3.1.1 the sum of (pounds)40,000,000 (forty million pounds) which sum
                  shall be paid on the Completion Date; and

            3.1.2 the sum agreed or determined in accordance with Clause 8
                  provided always that in no circumstances shall this sum exceed
                  (pounds)1,000,000 (one million pounds) and which sum shall be
                  paid on the Completion Date or, if such sum has not been
                  agreed or determined on the Completion Date, within 7 days of
                  such agreement or determination.

      3.2   The Purchase Price shall be apportioned (subject to adjustment in
            accordance with Clause 8) among the Assets as set out in Schedule 1.

4.    CONDITIONS


                                       14
   21

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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


      4.1   The sale and purchase of the Business and the Assets under this
            agreement is in all respects conditional upon:-

            4.1.1 the Purchaser being satisfied that there is a secure and
                  adequate supply of water to the Property for the purposes of
                  the Business including satisfactory results of a triangulation
                  survey (to be verified by the Purchaser's environmental
                  consultants) at the Property to establish the suitability of
                  ground water resource and the availability of at least 500,000
                  gallons of water a day which is not contaminated by salt and
                  is of an appropriate quality to be used in the Business and an
                  independent estimate of the cost and timing of sinking the
                  production well and a letter of intent from SEPA confirming
                  their consent to the construction of a pumping well on the
                  Property and the extraction from that well of up to 500,000
                  gallons of water per day for use in the Business and a letter
                  from the local planning authority confirming either that the
                  sinking of a production well would not require planning
                  permission, or (if it does) that planning consent would be
                  granted and a letter from the appropriate authority confirming
                  the availability of a public supply of water to the Property
                  and indicating the capacity of such supply and an estimate of
                  the cost, feasibility and timing of constructing a pipeline to
                  the Property and agreement between the Parties of the works to
                  be undertaken to secure such supplies, it being acknowledged
                  that the Vendor's liability to pay one half of the cost of
                  such works (set out in Clause 16.1) should be limited to an
                  amount to be agreed by the Parties;


                                       15
   22

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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            4.1.2 the board of directors of Chirex Inc voting in favor of making
                  the acquisition of the Business and the Assets;

            4.1.3 the Purchaser and the Vendor agreeing proposals regarding the
                  arrangements with Hoddam relating to Hoddam's rights to
                  extract water from the Pipeline, including the possible
                  termination of the Hoddam Agreement, it being acknowledged by
                  the Vendor that it may be appropriate as part of such
                  proposals that the Vendor grant the Purchaser an indemnity in
                  respect of any liabilities, or loss of rights of the Property
                  to extract water which such proposals might give rise to;

            4.1.4 the Purchaser being reasonably satisfied with the current
                  estimates of the Vendor in respect of any works, modification
                  or remedial action required in connection with the variation
                  of the existing IPC Authorizations or obtaining new IPC
                  Authorizations or expenditure otherwise required in respect of
                  the incinerator in excess of (pounds)650,000 it being
                  acknowledged that any increase in operating levels following
                  Completion would not be taken into account in assessing such
                  expenditure and that it may be appropriate for the Vendor to
                  give an indemnity in respect of such expenditure should the
                  existing estimates be insufficient;

            4.1.5 the Purchaser receiving satisfactory confirmation from the
                  Vendor that a manufacturing licence pursuant to the Medicines
                  Act 1968 and the Medicines Act 1971 is not required for the
                  operation of the Business;


                                       16
   23

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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            4.1.6 approval of third parties to transfer of contracts/licences;

            4.1.7 the Purchaser being satisfied with the results of any
                  outstanding due diligence enquiries which have been raised in
                  writing by or on behalf of the Purchaser prior to the date of
                  this agreement.

      4.2   The Vendor shall save in respect of clause 4.1.1 use all reasonable
            endeavours with the Purchaser's full assistance to procure that each
            of the conditions set out in Clause 4.1 are satisfied as soon as
            possible, (it being the intention that all such conditions are
            satisfied by 15 October 1997.)

      4.3   In the event of any of the conditions in Clause 4.1 not being
            satisfied or waived in writing by the Purchaser by 15 November 1997
            then the provisions of this agreement, (save for Clauses 21 and 22
            which shall continue in full force and effect) shall (unless the
            Parties otherwise agree in writing) be null and void and of no
            further effect and the Parties shall be released from their
            respective obligations under this agreement. For the avoidance of
            doubt the Secrecy Agreement shall continue to apply between the
            parties thereto.

5.    PERIOD BEFORE COMPLETION

      5.1   The Vendor undertakes that during the period from the date of this
            agreement until the Completion Date it will procure that the
            Business is carried on in substantially the same manner as
            heretofore, so as to maintain the same as a going concern and
            without prejudice to the generality of the foregoing (unless the
            Purchaser shall previously have agreed otherwise in writing) the
            Vendor will procure that it or (as appropriate) GWO will in relation
            to the Business:-


                                       17
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


            5.1.1 not enter into any contract or commitment of an unusual nature
                  or which is other than in the ordinary course of business;

            5.1.2 not institute changes in management policy of a significant
                  nature;

            5.1.3 not purchase stock, raw materials, or intermediates of a kind
                  or in quantities other than as may be reasonably necessary for
                  the operation of the Business in the ordinary course and so as
                  to maintain quantities of stock, raw materials and
                  intermediates consistent with the previous operation of the
                  Business;

            5.1.4 not terminate the employment of any of the Employees or alter
                  any existing term of their employment or engage more
                  employees;

            5.1.5 not do or suffer to be done any act or thing which may
                  immediately or in the future adversely affect the Goodwill;

            5.1.6 not enter into any agency, distribution, advertising,
                  maintenance or other similar contract;

            5.1.7 consult the Purchaser prior to taking action in relation to
                  any matters of importance in connection with the Business;

            5.1.8 allow the Purchaser and its representatives reasonable access
                  to the Property and to the books, documents, files and records
                  of the Business on prior notice and subject to the observance
                  by the Purchaser of the site procedures in operation at the
                  Property and subject to making good any damage caused by the


                                       18
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                     Purchaser or its representatives to the Property;

              5.1.9  use all reasonable endeavours to assist the Purchaser in
                     the assignment, transfer or grant to the Purchaser of all
                     statutory or regulatory licences necessary for the
                     Purchaser to carry on the Business;

              5.1.10 maintain the supply of all utilities required in connection
                     with the Business on terms no less favorable than those
                     which exist at the date of this agreement; and

              5.1.11 keep in force its existing insurance policies as disclosed
                     to the Purchaser in respect of the Business and the Assets.

6.     COMPLETION

       6.1    Completion of the sale and purchase of the Business and Assets
              shall take place on 15 October 1997 or (if later) three Business
              Days after the satisfaction or waiver of the last of the
              conditions in Clause 4 to be satisfied or waived. Completion shall
              take place at such location as is agreed by the Parties.

       6.2    At Completion the Vendor shall:-

              6.2.1  permit the Purchaser to assume the conduct of the Business
                     and possession of those of the Assets capable of passing by
                     delivery and the Purchaser will carry on the Business with
                     effect from the Completion Date;

              6.2.2  complete the sale or procure the completion of the sale to
                     the Purchaser of the Property in accordance with the terms
                     contained in or referred to in Schedule 3;


                                       19
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                  6.2.3    deliver to the Purchaser:-

                           6.2.3.1  the Disposition and any other items required
                                    to be delivered at Completion in terms of
                                    Schedule 3;

                           6.2.3.2  the Deeds and Documents;

                           6.2.3.3  the Information Technology Services
                                    Agreement;

                           6.2.3.4  the Supply Agreement;

                           6.2.3.5  the Secondment Letter;

                           6.2.3.6  duly executed assignments in agreed terms
                                    together with such other documents as the
                                    Purchaser may reasonably require to perfect
                                    its title to the Goodwill, the Intellectual
                                    Property, the Contracts and the Lease
                                    Contracts;

                           6.2.3.7  the Records;

                           6.2.3.8  all national insurance contributions and
                                    PAYE records duly completed and up to date
                                    in respect of the Employees;

                           6.2.3.9  all contracts of employment, statements of
                                    terms and conditions and all personnel
                                    records, files and details relating to the
                                    Employees;

                           6.2.3.10 the value added tax records referred to in
                                    Clause 17;


                                       20
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                           6.2.3.11 a letter from the Vendor (or the appropriate
                                    Vendor Group Company) transferring the IPC
                                    Authorizations to the Purchaser;

                           6.2.3.12 the Disclosure Letter;

                           6.2.3.13 the Employment Letter; and

                           6.2.3.14 the Glaxo Wellcome plc Letter.

       6.3    Upon fulfilment by the Vendor of its obligations under Clause 6.2
              the Purchaser shall:

              6.3.1  procure the payment by electronic funds transfer of the
                     sums due and payable under Clause 3 to National Westminster
                     Bank Plc sort code 50/00/OT account number 00462616 account
                     name Glaxo Group Limited; and

              6.3.2  deliver to the Vendor duly executed counterparts of the
                     documents referred to in Clause 6.2 as are required to be
                     executed by the Purchaser.

       6.4    The Purchaser shall not be obliged to complete the purchase of any
              of the Assets unless the purchase of all the Assets is completed
              in accordance with this agreement.

7.     REIMBURSEMENT OF COSTS

       7.1    The Purchaser undertakes that it will within 28 days of receipt by
              it of any relevant suppliers invoice, reimburse the Vendor the
              External Costs. The Purchaser shall have no liability under this
              clause unless it shall have given its written approval to any
              External Costs before any such costs are incurred by the Vendor.
              Such approval may be given by the Purchaser in respect of each
              specific item of cost or by approval of such costs within a
              specific project.


                                       21
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       7.2    The Vendor shall reimburse the Purchaser for any VAT in respect of
              such costs for which the Purchaser is liable and which is
              irrecoverable by the Purchaser.

       7.3    In the event that Completion has not taken place, for any reason
              whatsoever, by 15 November 1997 the Vendor shall repay forthwith
              to the Purchaser all sums paid by the Purchaser under Clause 7.1.

       7.4    The Vendor shall reimburse any costs (not exceeding the GWO budget
              and interest) incurred by the Purchaser in respect of the Business
              in the period from the date of this agreement to 31 December 1997
              insofar as such costs exceed the revenues of the Business to which
              the Purchaser is entitled during that period. The Vendor shall be
              entitled to require the Purchaser to provide such information as
              it reasonably requires to monitor and challenge any costs
              schedules produced by the Purchaser.

8.     COMPLETION STATEMENT

       8.1    On the Completion Date or as soon as practicable thereafter the
              Vendor shall carry out a physical count and a valuation of the
              Stock and Work in Progress as at the Completion Date. The
              Purchaser and its representatives shall be entitled to attend such
              count and valuation.

       8.2    The Stock and Work in Progress will (subject to the further
              provisions of this clause) be valued at the lower of cost and net
              realizable value using the same methods and bases (as nearly as
              may be practicable and insofar as they are consistent with good
              accounting and valuation practice and with all applicable SSAP's
              and FRS's) as those consistently adopted by the Vendor in the
              valuations of similar items for the purposes of the Accounts. No
              value will be attributed to any Stock or Work in Progress which is
              Defective, Obsolete or outside of its Shelf-Life. Provided 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              Always that if the value of the Stock and Work in Progress (when
              valued in accordance with the provisions of this Clause 8.2)
              would, but for this proviso, exceed(pounds)1,000,000 it shall be
              certified as being and for all purposes relating to this agreement
              shall be (pounds)1,000,000.

       8.3    The Vendor will procure that a written certificate of the value of
              the Stock and Work in Progress calculated on the basis set out or
              referred to in Clause 8.2 ("the Completion Statement") is
              delivered to the Purchaser as soon as practicable following the
              Completion Date and in any event not later than 3 Business Days
              following such date. The Purchaser may within the period of 3
              Business Days following delivery of the Completion Statement by
              notice in writing to the Vendor dispute the value set out in the
              Completion Statement. If no such notice is received or if within
              the said period of 3 Business Days the value of the Stock and Work
              in Progress as set out in the Completion Statement or any amended
              amount is agreed between the Vendor and the Purchaser then the
              value as set out in the Completion Statement or (as the case may
              be) any amended amount shall be conclusive and binding upon the
              parties for the purposes hereof.

       8.4    If the Purchaser shall give notice of any dispute under Clause 8.3
              which is not resolved within the said period of 3 Business Days,
              such dispute shall be referred for determination in accordance
              with Clause 20.

9.     CONTRACTS

       9.1    With effect from the Completion Date the Purchaser shall take
              over, perform and complete the Contracts.

       9.2    Insofar as the benefit of any of the Contracts or Lease Contracts
              cannot effectively be transferred 


                                       23
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confidential treatment. The omitted portions are marked **** and have been filed
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              to the Purchaser (whether by assignment, novation or otherwise)
              without the consent of a third party and such consent has not been
              obtained at or prior to Completion:-

              9.2.1  the Vendor shall use all reasonable endeavours to obtain
                     such consent as soon as practicable;

              9.2.2  unless and until any such contract has been transferred to
                     the reasonable satisfaction of the Purchaser, the Purchaser
                     shall for its own benefit and to the extent that the
                     contract in question permits without constituting a breach
                     thereof, perform on behalf of the Vendor (but at the
                     Purchaser's expense) all the Vendor's obligations and the
                     Vendor will co-operate with the Purchaser (at the Vendor's
                     expense) in any reasonable arrangements designed to provide
                     for the Purchaser the benefits under any such contracts
                     including the enforcement of any and all rights of the
                     Vendor thereunder;

              9.2.3  in the event that any such contract cannot be fully and
                     effectually transferred to the Purchaser, the Parties shall
                     use their respective reasonable endeavours to procure that
                     the contract in question is terminated without liability to
                     the Parties. If termination without liability to the
                     Parties cannot be achieved the Purchaser shall have no
                     further obligation to the Vendor relating to the contract
                     in question and the Vendor shall indemnify the Purchaser
                     against any costs, claims, damages, liabilities, or
                     expenses arising from claims by any third party in relation
                     to the contract in question and the termination, assignment
                     or attempted 


                                       24
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


assignment of such contract without consent;

              9.2.4  if the Purchaser shall require, the Vendor shall enter into
                     novation agreements with the other parties to any of such
                     contracts to the intent that thenceforth the Purchaser
                     shall be in a direct contractual relationship with such
                     other parties.

10.    CREDITORS AND LIABILITIES

       10.1   The Vendor shall remain responsible for and shall promptly pay,
              discharge or satisfy all debts payable by the Vendor and other
              obligations and liabilities arising from or attributable to the
              carrying on of the Business prior to the Completion Date (save for
              any which are expressly assumed by the Purchaser under this
              agreement) including without limitation:-

              10.1.1 all liabilities to trade and other creditors including
                     banks and all liabilities in respect of Tax of the Vendor
                     or any company within the Vendor's Group;

              10.1.2 all liabilities and obligations accrued or falling to be
                     performed under the Contracts and the Lease Contracts up to
                     the Completion Date; and

              10.1.3 all claims made by third parties on or after the Completion
                     Date in respect of any goods or services supplied by the
                     Vendor or any company within the Vendor's Group or any act
                     or omission of the Vendor or any company within the
                     Vendor's Group prior to the Completion Date.

              The Vendor shall if so requested by the Purchaser promptly supply
              to the Purchaser written details 


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confidential treatment. The omitted portions are marked **** and have been filed
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              of all trade and other creditors of the Business subsisting at the
              Completion Date.

       10.2   The Vendor shall fully and effectively indemnify and keep
              indemnified the Purchaser against any liability, loss, damage,
              penalty, cost or expense (including reasonable legal and other
              professional fees) incurred in defending or resolving any actions
              or claims (civil or criminal) or in appealing against any
              judgment, notice or award and also including the cost of remedial
              work under or pursuant to or carried out to avoid the application
              of any Environmental Laws, which are suffered or incurred by the
              Purchaser and which arise out of the past use of the Property
              (including any activity, trade, business or operation carried out
              on the Property at anytime) whether arising before or after
              Completion and including, but without limitation, any liability,
              loss, damage, penalty, cost or expense arising directly or
              indirectly from the oil spillage which occurred on the Property in
              1992. Provided that the Vendor shall not be liable under this
              clause 10.2 if and to the extent that the matter giving rise to
              the claim would not have arisen but for the passing of or a change
              in, after the date of Completion a law, or regulation not actually
              prospectively in force at the date of this agreement. For the
              purposes of this clause Part IIA of the Environment Protection Act
              1990 as inserted by the Environment Act 1995 as it is brought into
              force and the first complete set of guidance and regulations
              adopted thereunder, and the amendment to Sections 161A to D of the
              Water Resource Act 1991 as inserted by the Environment Act 1995
              shall be deemed to be in force at the date of this agreement.

       10.3   The maximum liability of the Vendor under Clause 10.2 shall be
              ****.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       10.4   The Vendor is not liable under Clause 10.2 unless the Purchaser
              has given the Vendor written notice of the matter under Clause
              10.2 on or before the date which is **** after the Completion
              Date.

       10.5   If the Vendor pays to the Purchaser an amount under Clause 10.2
              and the Purchaser or any member of the Purchaser's Group
              subsequently recovers from a third party an amount which is
              directly referable to the matter giving rise to the claim under
              Clause 10.2 then:

              10.5.1 if the amount paid by the Vendor in respect of the claim
                     under Clause 10.2 is more than the sum recovered from the
                     third party, the Purchaser shall pay the Vendor the sum so
                     recovered; and

              10.5.2 if the amount paid by the Vendor in respect of the claim
                     under Clause 10.2 is less than or equal to the sum
                     recovered from the third party, the Purchaser shall pay the
                     Vendor an amount equal to the amount paid by the Vendor;

              For the purposes of this Clause 10.5 the "sum recovered" means an
              amount equal to the amount recovered from the third party less all
              reasonable costs and expenses incurred by the Purchaser or any
              member of the Purchaser's Group in recovering the amount from the
              third party.

       10.6   The Purchaser shall as soon as reasonably practicable give written
              notice to the Vendor of any matter which it becomes aware which is
              likely to give rise to a claim under Clause 10.2 and shall consult
              with the Vendor in respect to the matter and the Vendor shall be
              entitled to make such reasonable investigation into the matter as
              it thinks fit. If the Purchaser fails, for whatever reason, to
              comply with the terms of this Clause any such failure shall not
              affect the 


                                       27
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              Purchaser's ability to make a claim under Clause 10.2.

       10.7   If and to the extent that the matter giving rise to the claim
              under Clause 10.2 concerns the reduction in value of the Property
              as a consequence of the Purchaser using and operating the Property
              for purposes other than pharmaceutical and intermediate
              manufacturing (including without limitation the use of the
              Property for residential uses or public recreation).

       10.8   Unless otherwise expressly provided, nothing in this agreement
              shall make the Purchaser liable in respect of anything done or
              omitted to be done by the Vendor or any company within the
              Vendor's Group prior to the Completion Date and the Vendor shall
              indemnify the Purchaser in full for and against any claims, costs,
              expenses or liabilities whatsoever and howsoever arising incurred
              or suffered by the Purchaser in connection with any of the debts,
              obligations and liabilities referred to in Clause 10.1 including
              costs incurred by the Purchaser in settling any claim in respect
              of such debts, obligations or liabilities. This indemnity shall
              extend without limitation to all legal expenses and other
              professional fees reasonably and properly incurred by the
              Purchaser.

       10.9   With effect from the Completion Date the Purchaser shall:-

              10.9.1 observe and perform or procure to be observed and performed
                     all the obligations of GWO under the Contracts and the
                     Lease Contracts except insofar as such obligations should
                     have been performed at or before the Completion Date and
                     except insofar as such obligations have not been fully and
                     effectively transferred to the Purchaser whether by
                     assignment, novation 


                                       28
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                     or otherwise and it is not possible for the Purchaser to
                     perform or procure the performance thereof without
                     constituting a breach of the contract concerned;

              10.9.2 assume responsibility for payment for all goods delivered
                     or services received under the Contracts after the
                     Completion Date and which do not form part of the Stock or
                     Work in Progress whether the invoices for such goods or
                     services are received before or after the Completion Date;

              10.9.3 keep the Vendor and GWO fully and effectively indemnified
                     against any liability howsoever arising from the Contracts
                     or the Lease Contracts as a result of any act or omission
                     of the Purchaser after Completion.

11.    EMPLOYEES

       11.1   The Parties acknowledge that pursuant to the Regulations at the
              Completion Date the Purchaser it will become the employer of the
              Employees (but not the Excluded Employees).

       11.2   The Vendor shall indemnify the Purchaser in full for and against
              all claims, costs, expenses or liabilities whatsoever and
              howsoever arising incurred or suffered by the Purchaser including
              without limitation all legal expenses and other professional fees
              (together with any VAT thereon) arising out of or in respect of
              the employment or the termination of the employment of any of the
              Employees up to and including the Completion Date or arising out
              of the employment or the termination of the employment of the
              Excluded Employees or any other person in respect of the Business
              at any time.


                                       29
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       11.3   The Purchaser shall indemnify the Vendor and/or GWO in full for
              and against all claims, costs, expenses or liabilities whatsoever
              and howsoever arising incurred or suffered by the Vendor and/or
              GWO including without limitation any reasonable legal expenses and
              other professional fees (together with any VAT thereon) arising
              out of or in respect of the termination of the employment of the
              Employees after the Completion Date.

       11.4   The Vendor warrants that the Vendor and/or GWO (as applicable)
              have complied with Regulation 10 of the Regulations and will
              indemnify the Purchaser against any compensation for which the
              Purchaser may become liable as a result of any breach thereof by
              the Vendor. The Vendor shall have no liability to the Purchaser
              under this clause to the extent that any failure on its or GWO's
              part to comply with Regulation 10 is as a result of a failure on
              the part of the Purchaser to provide the Vendor with such
              information as the Vendor has requested regarding the Purchaser
              and its plans for the Business following Completion.

       11.5   All salaries and other emoluments including holiday pay, taxation
              and national insurance contributions and contributions to
              retirement benefit schemes relating to the Employees shall be
              borne by the Vendor up to and including the Completion Date and by
              the Purchaser with effect from the Completion Date and all
              necessary apportionments shall be made.

12.    PENSIONS

       The provisions set out in Schedule 4 shall apply to the Employees and
       govern their rights under the Disclosed Schemes.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


13.   APPORTIONMENT

       13.1   All rents, rates, gas, water, electricity, telephone charges and
              other outgoings relating to or payable in respect of the Business
              up to and including the Completion Date shall be borne and paid by
              the Vendor and as from the Completion Date shall be borne and paid
              by the Purchaser and shall be apportioned accordingly.

       13.2   All rents, royalties and other periodical payments receivable in
              respect of the Business up to the Completion Date shall belong and
              be payable to the Vendor and as from that time shall belong to and
              be payable to the Purchaser and shall be apportioned accordingly.

       13.3   The benefit of any prepayments, deposits or payments in advance
              made to the Vendor on or before the Completion Date in respect of
              goods and services to be supplied by the Purchaser after the
              Completion Date shall belong to the Purchaser and the benefit of
              any prepayments, deposits and payments in advance made by the
              Vendor in respect of goods ordered but not delivered and services
              contracted for but not rendered to the Vendor in connection with
              the Business on or before the Completion Date shall be reimbursed
              by the Purchaser to the Vendor.

       13.4   Any amount due from the Vendor or the Purchaser pursuant to
              Clauses 13.1, 13.2 or 13.3 shall be paid within 14 days of written
              request from the Purchaser or the Vendor (as the case may be) for
              the amount thereof together with supporting vouchers. If any
              dispute shall arise as to the amount of any apportionment
              hereunder such dispute shall be referred for final determination
              in accordance with Clause 20.

14.    WARRANTIES


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       14.1   The Vendor warrants and represents to the Purchaser as at the date
              of this agreement in the terms of the Warranties.

       14.2   The Vendor shall further warrant and represent as at the
              Completion Date to the Purchaser in the terms of the Warranties as
              if they had been entered into afresh at Completion by reference to
              the facts and circumstances then existing.

       14.3   Each of the Warranties shall be construed as a separate and
              independent warranty and (save where expressly provided to the
              contrary) shall not be limited or restricted by reference to or
              inference from any other terms of this agreement or any other
              Warranty.

       14.4   The rights and remedies of the Purchaser in respect of any breach
              of any of the Warranties shall continue to subsist notwithstanding
              Completion.

       14.5   The Vendor hereby undertakes with the Purchaser that it will
              forthwith disclose in writing to the Purchaser any event or
              circumstance which may arise or become known to it after the date
              hereof and prior to Completion which is materially inconsistent
              with any of the Warranties or which has or is likely to have an
              adverse effect on the financial position or business prospects of
              the Business or which is otherwise material to be known by a
              purchaser for value of the Business.

       14.6   The Purchaser shall be given all such facilities as it (or its
              authorized representatives) may reasonably require to enable the
              Purchaser to be satisfied with regard to the accuracy of the
              Warranties provided that the Warranties shall not be deemed in any
              way modified or discharged by reason of any investigation made or
              to be made by or on behalf of the Purchaser or by reason of any
              information relating to the Business of which 


                                       32
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              the Purchaser has knowledge (actual implied or constructive)
              except such information as is fully and fairly disclosed in the
              Disclosure Letter.

       14.7   In the event of any breach or non-fulfilment of any of the
              Warranties resulting in:-

              14.7.1 the value of the Goodwill and/or any of the other Assets
                     being or becoming less than it would have been had the
                     relevant circumstances been as so warranted; or

              14.7.2 the Purchaser having incurred or incurring any liability
                     which it would not have incurred had the relevant
                     circumstances been as so warranted;

              then without prejudice to any other rights or remedies available
              to the Purchaser and without restricting its ability to claim
              damages on any other basis the Vendor agrees to pay to the
              Purchaser on demand an amount sufficient to make good the
              diminution in the value of the Goodwill and/or other Assets or an
              amount equal to the liability thereby incurred.

       14.8   The Vendor hereby agrees to indemnify the Purchaser in full for
              and against all costs (including reasonable legal costs) and
              expenses (together with any VAT thereon) incurred by the Purchaser
              either before or after the commencement of any action in
              connection with:-

              14.8.1 the settlement of any claim that any of the Warranties has
                     been breached or is untrue inaccurate or misleading;

              14.8.2 any legal proceedings arising out of or in connection with
                     any claim or breach of any of the Warranties in which
                     judgment is given in favour of the Purchaser; or


                                       33
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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              14.8.3 the enforcement of any such settlement or judgment.

       14.9   The rights of the Purchaser under Clauses 14.7 and 14.8 shall be
              in addition and without prejudice to any other right or remedy
              available to it under this agreement or otherwise.

       14.10  Any amount paid by the Vendor to the Purchaser in respect of a
              breach of Warranty shall be treated primarily as a reduction in
              the Purchase Price.

       14.11  The Warranties shall be qualified by matters fully and fairly
              disclosed in the Disclosure Letter but shall otherwise be subject
              to no qualification whatsoever.

       14.12  The Purchaser acknowledges that no representations, or warranties
              express or implied are given by the Vendor in relation to the
              Business other than the Warranties themselves.

       14.13  The provisions of Schedule 6 shall have effect in respect of the
              matters to which this Clause 14 applies to limit the liability of
              the Vendor in respect of the Warranties.

15.    RIGHT TO RESCIND

       15.1   If the Vendor shall disclose any event or circumstance pursuant to
              sub-clause 14.5 or if there is a breach of any of the Warranties
              or a breach or non-fulfilment of any other term of this agreement
              by the Vendor, the Purchaser shall be entitled in addition and
              without prejudice to any other right or remedy available to it to
              rescind this agreement without any liability to any other party
              whereupon the Vendor shall indemnify the Purchaser in full for and
              against all claims, costs, expenses and liabilities incurred or
              suffered by the Purchaser (including but not limited to all legal
              and other professional fees 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              and expenses) in connection with the negotiation, preparation and
              rescission of this agreement as are incurred after the date of
              this agreement.

       15.2   The Purchaser shall not be entitled to exercise its right of
              rescission under Clause 15.1 unless the matter in question in the
              reasonable opinion of the Purchaser (having first discussed the
              matter with the Vendor) has had or is likely to result in a
              reduction in the value of the Assets of(pounds)1,000,000 or more.
              In arriving at its opinion as to whether such matter will have or
              has had such an effect the Purchaser shall act reasonably and in
              good faith and shall take into account the availability of
              insurance receipts in respect of such matter.

16.   POST COMPLETION OBLIGATIONS

       16.1   The Vendor undertakes to indemnify and keep indemnified the
              Purchaser against all liabilities, losses, obligations, costs,
              claims, damages, demands and expenses arising directly or
              indirectly out of the provision of a secure and adequate supply of
              at least 500,000 gallons a day of non saltwater water to the
              Property which is suitable for the purposes of the Business
              provided that the Vendor's liability under clause 16.1 shall be
              limited to 50% of such costs and the Vendor's liability shall be
              limited to such amount as is agreed pursuant to Clause ?.

       16.2   The Vendor undertakes to provide to the Purchaser in respect of
              the manufacturing site at Annan:

              16.2.1 within 10 Business Days of Completion audited financial
                     statements for the years ended 31 December 1994, 31
                     December 1995 and 31 December 1996;


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              16.2.2 within 10 Business Days of Completion, copies of the
                     unaudited financial statements to Completion;

              16.2.3 within 28 days of Completion, copies of the audited balance
                     sheet and profit and loss accounts for the period from 31
                     December 1996 to Completion;

              16.2.4 by the later of 30 November 1997 and 28 days after
                     Completion unaudited quarterly accounts in respect of the
                     period from 1 January 1996 (being audited as at 31 December
                     1996) to Completion. In respect of any costs incurred by
                     the Vendor under this Clause 16.2.4 the Purchaser shall, if
                     required, pay the actual cost of any temporary assistance
                     up to a maximum of (pounds)5,000.

       16.3   The Vendor undertakes to the Purchaser to maintain adequate
              insurance in respect of Finished product at the Property both
              before and after Completion.

       16.4   The Vendor undertakes to obtain from the Vendor's Accountants
              authority to use any financial information available or required
              in respect of the Business (whether before or after Completion)
              under the requirements of the Securities and Exchange Commission
              and the Securities Act of 1933 and the Securities Exchange Act of
              1934 of the United States and to procure the co-operation of the
              Vendor's Accountants in respect of any public offering of Chirex
              Inc., including providing any customer comfort letters required by
              any underwriters of such offering and to procure access to any
              underlying records of the Vendor's Accountants or the Vendor's
              Group.

       16.5   The Parties undertake to one another that all Records delivered to
              the Purchaser at Completion shall be retained by the Purchaser and
              all the 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              Retained Records shall be retained by the Vendor and each Party
              shall make available for inspection and reasonable use by the
              other Party all such books, records and other documents retained
              by it (or transferred to it as the case may be) relating to the
              Business as the other Party may request in finalizing its affairs
              in relation to the transfer of the Business and the Assets
              pursuant to this agreement and to give effect to this agreement.
              The rights and obligations contained in this clause shall expire
              on the sixth anniversary of Completion, save in respect of
              particular records (including but not limited to Control of
              Substances Hazardous to Health records) in respect of which there
              is a legal obligation to retain such Records for a longer period.
              The Purchaser undertakes to maintain and, on request, provide to
              the Vendor samples of Products (as are available on Completion)
              manufactured by the Vendor at the Property.

       16.6   The Purchaser shall procure at the Vendor's cost that for a period
              of 12 months after Completion those of the Employees whose
              assistance is reasonably required by the Vendor in connection with
              matters arising from its carrying out the Business prior to the
              Completion Date will be available at reasonable times to assist
              the Vendor provided that such assistance does not unduly interfere
              with their day-to-day function within the Business.

17.    VALUE ADDED TAX

       17.1   The purchase price of the Assets and the Business stated in this
              agreement is exclusive of VAT.

       17.2   The parties intend that the provisions of section 49 of the Value
              Added Tax Act 1994 and Article 5 of the Value Added Tax (Special
              Provisions) Order 1995 shall apply to the sale of the Business and
              the Assets and, accordingly, no VAT shall be 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              charged by the Vendor on them. The Vendor and the Purchaser shall
              each promptly following Completion inform their respective VAT
              offices of the sale and purchase under this agreement, complete
              all relevant forms for VAT purposes relating to such sale and
              purchase and take all reasonable steps to ensure that the sale of
              the Business and Assets is treated neither as a supply of goods
              nor a supply of services for the purposes of VAT but as the
              transfer of a going concern. In the event that it is at any time
              determined by HM Customs and Excise or, on appeal, by the tribunal
              or the court that section 49 of the Value Added Tax Act 1994 and
              Article 5 of the Value Added Tax (Special Provisions) Order 1995
              do not apply to the sale of the Business and Assets or any part of
              them, the Purchaser shall pay to the Vendor the amount of the VAT
              in question on the later of the business day before such amount is
              due to be paid by the Vendor to Customs & Excise and the day on
              which the Vendor delivers to the Purchaser a valid VAT invoice or
              invoices in respect thereof. Subject to the Vendor having complied
              with its obligations under this Clause 17 the Purchaser shall in
              addition pay any penalty and interest imposed by Customs and
              Excise in respect of late payment of such VAT.

       17.3   For the purposes of the said Article 5, the Vendor warrants that
              it carries on, and that it will immediately prior to Completion
              carry on, the Business.

       17.4   The Vendor shall, at Completion, deliver to the Purchaser all the
              records of the Business for VAT purposes which are required to be
              preserved by the Purchaser by section 49(1)(b) of the Value Added
              Tax Act 1994, and the Purchaser shall, for a period of not less
              than six years from the Completion Date, preserve the records so
              delivered and, upon reasonable notice, during normal 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              business hours make them available for inspection to the Vendor or
              its agent.

       17.5   The Purchaser confirms that it will be registered for VAT and will
              carry on the Business as a going concern immediately after
              Completion.

       17.6   The Purchaser confirms that it shall not apply for a reallocation
              of the Vendor's VAT registration number.

       17.7   The Vendor agrees that it will not at any time before Completion
              without the consent of the Purchaser exercise its right under VAT
              1994 Schedule 10 paragraph 2 to elect to tax the Property.

18.    CAPITAL GOODS SCHEME

       The Vendor will provide the Purchaser with all records and other
       information required by the Purchaser for the purposes of the Capital
       Goods Scheme in Part XV Value Added Tax Regulations 1995 (SI1995/2518)
       and any adjustments thereunder.

19.    FURTHER ASSURANCE

       19.1   Upon and at any time after Completion the Vendor shall at the
              request of the Purchaser and at the Vendor's cost do and execute
              or procure to be done and executed all such acts deeds documents
              and things as may be reasonably necessary to vest the title to the
              Business and Assets in the Purchaser and to give effect to this
              agreement.

       19.2   The Vendor will use all reasonable endeavours to ensure that all
              relevant authorisations, permissions, consents, licences or
              agreements are (where necessary) transferred to the Purchaser or,
              as the case may be, renewed. In particular, but without
              limitation, the Vendor shall assist the Purchaser in making
              application to or providing information to any relevant authority
              for the purpose of such transfer or renewal.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       19.3   Without prejudice to the terms of clause 19.1 the Vendor shall at
              the request of the Purchaser and at the Vendor's cost, execute or
              procure to be done and executed all such acts, documents and
              things as may be necessary or desirable in connection with:

              19.3.1 the loss of the original title deeds to the Property; and

              19.3.2 the application by the Purchaser to register the title to
                     the Property.

       19.4   The Vendor will at any time after Completion, at the Purchasers
              cost and at the request of the Purchaser execute such documents
              and give such assistance as is reasonable in ensuring that a
              secure and adequate supply of water is available to the Property
              for the purpose of the Business.

20.    DISPUTE RESOLUTION

       If there is a dispute between the Vendor and the Purchaser, pursuant to
       Clause 8.4 and/or 13.4, which the Vendor's Accountants and the
       Purchaser's Accountants cannot resolve, then the matter in dispute shall
       be referred to an independent firm of Chartered Accountants nominated
       jointly by them or if no such nomination is made within 14 days after the
       expiry of one party requiring nomination, nominated at the request of
       either of them by the President for the time being of the Institute of
       Chartered Accountants in England and Wales. The Accountants so nominated
       shall be entitled to ask for and inspect the working papers, records and
       documents of both Parties as they may reasonably consider necessary. In
       making their determination, the said Accountants shall act as experts and
       not as arbitrators, their decision shall (in the absence of manifest
       error) be final and binding on the Parties and their fees shall be borne
       and paid by the Vendor and the Purchaser in such proportions as the
       Accountants determine in the light of the 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       respective contentions of the Parties, and the Accountants'
       determination.

21.    SECONDMENT

       21.1   The Vendor undertakes to use its best endeavours to procure that
              at least 40 Employees are seconded during the period from
              Completion to 31 December 1998 to a Vendor Group Company on the
              terms set out in the Secondment Letter. The Vendor shall:

              21.1.1 make available, within the Vendor's Group, 40 suitable
                     positions for secondees of the Business;

              21.1.2 identify (after consultation with the Purchaser) 40
                     Employees suitable for secondment, and not required for the
                     Business during the period from Completion to 31 December
                     1998;

              21.1.3 make proposals, as soon as practicable, to such Employees
                     for their secondment; and

              21.1.4 use its reasonable endeavours to persuade such Employees to
                     accept its offer of secondment which may include increasing
                     relocation/secondment benefits.

       21.2   The Purchaser shall, following Completion use its reasonable
              endeavours to persuade such Employees to accept the offer of
              secondment made to them.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


22.    ANNOUNCEMENTS

       No announcement, communication or circular in connection with the subject
       matter of this agreement shall be made (prior to or after the Completion
       Date) by or on behalf of the Vendor or the Purchaser without the prior
       approval of the other (such approval not to be unreasonably withheld or
       delayed) save for:-

       22.1   announcements to Employees, customers, suppliers and agents of the
              Purchaser and the Business in such form as may be agreed between
              the Parties; and

       22.2   such announcements, documents, and other information as may be
              required by any recognized stock exchange or the Securities
              Exchange Commission and/or as required under the Securities Act of
              1933 and the Securities Exchange Act of 1934 or which would be
              customary for the Purchaser to make to investors, stockholders,
              analysts and within the Purchaser's Group.

23.    COSTS

       Subject to the provisions of Clause 15 each of the Parties shall bear and
       pay its own legal, accountancy and other fees and expenses incidental to
       the preparation and implementation of this agreement and all other
       documents in the agreed form referred to herein.

24.    SUCCESSORS AND ASSIGNMENT

       No Party may assign or transfer, or purport to assign or transfer, any of
       its rights or obligations under this agreement, save that the Purchaser
       shall be entitled to assign the benefit of the Warranties to any company
       in the Purchaser's Group.

25.    ENTIRE AGREEMENT


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       25.1   This agreement (together with the documents referred to in it) and
              the Secrecy Agreement constitute the entire agreement between the
              parties in connection with its subject matter.

       25.2   Neither Party has relied on any representation or warranty except
              as expressly set out in this agreement.

26.    TIME OF THE ESSENCE

       As regards any time date or period mentioned in this agreement time shall
       be of the essence.

27.    NOTICES

       Any notice to be given pursuant to the terms of this agreement must be
       given in writing to the Party due to receive such notice at its
       registered office from time to time or at its address set out in this
       agreement or such other address as may have been notified for the purpose
       to the other Parties in accordance with this clause. Notice shall be
       delivered personally or sent by first class pre-paid recorded delivery or
       registered post (air mail if overseas) or by facsimile transmission and
       shall be deemed to be given in the case of personal delivery on delivery
       and in the case of posting (in the absence of evidence of earlier
       receipt) within 48 hours after posting (6 days if sent by air mail) and
       in the case of facsimile transmission on completion of the transmission.

28.    AGREEMENT CONTINUES IN FORCE

       This agreement shall remain in full force and effect so far as concerns
       any matter remaining to be performed at Completion and notwithstanding
       that Completion shall have taken place and in respect of any indemnities
       and undertakings on the part of the Vendor (including without prejudice
       to the generality those contained in Clauses 16 and 19, the Vendor shall
       at the Purchaser's request but at the Vendor's cost grant to the
       Purchaser, at intervals of not less than four years, 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       written confirmation (in such form as the Purchaser may require) that
       this Clause remains fully binding on the Vendor notwithstanding the
       passage of time.

29.    SEVERABILITY

       The invalidity, illegality or unenforceability of any provision of this
       agreement shall not affect the continuation in force of the remainder of
       this agreement.

30.    WAIVER

       No waiver by the Purchaser of any breach or non-fulfilment by the Vendor
       of any provision of this agreement shall be deemed to be a waiver of any
       subsequent or other breach of that or any other provision hereof and no
       failure to exercise or delay in exercising any right or remedy under this
       agreement shall constitute a waiver thereof. No single or partial
       exercise of any right or remedy under this agreement shall preclude or
       restrict the further exercise of any such right or remedy. The rights and
       remedies of the Purchaser provided in this agreement are cumulative and
       not exclusive of any rights and remedies provided by law.

31.    VARIATIONS

       No variation of this agreement or any of the documents in the agreed
       terms shall be valid unless it is in writing and signed by or on behalf
       of each of the Parties.

32.    COUNTERPARTS

       This agreement may be executed in any number of counterparts each of
       which when executed by one or more of the Parties shall constitute an
       original but all of which shall constitute one and the same instrument.

33.    FUNDING

       The Vendor shall give due consideration prior to Completion to any
       comments made by funders of the 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       Purchaser's Group in relation to the terms of this agreement.

34.    GOVERNING LAW

       34.1   Subject to the provisions of Clause 34.2 below, this agreement
              shall be governed by and construed in accordance with English Law
              and, subject to Clause 20, the Parties hereby submit for all
              purposes in connection with this agreement to the exclusive
              jurisdiction of the English Courts.

       34.2   The provisions of Schedule 3 and the Property Warranties are to be
              interpreted in accordance with Scots Law.

AS WITNESS the hands of the Parties or their duly authorized representatives the
day and year first above written

SIGNED by                             )
for and on behalf of GLAXO            )   /s/ Dr. G. Joseph Blaker
GROUP LIMITED in the presence of:-    )               
                                                      Dr. G. Joseph Blaker

Witness


Name


Address

SIGNED by                             )
for and on behalf of                  )   /s/ Michael A. Griffith
CHIREX (ANNAN) LIMITED                )
in the presence of:-                  )               Michael A. Griffith


Witness


Name


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


Address


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                                   SCHEDULE 1

                                     Part 1

                         Apportionment of Purchase Price

================================================
Asset                       Purchase Price
- ------------------------------------------------
Contracts                   (pounds)1
- ------------------------------------------------
Equipment                   (pounds)24,000,000
- ------------------------------------------------
Fixed Plant (Non            (pounds)1,000,000
Qualifying)
- ------------------------------------------------
Fixed Plant                 (pounds)5,000,000
(Qualifying)
- ------------------------------------------------
Goodwill                    (pounds)7,000,000
- ------------------------------------------------
Intellectual                (pounds)1
Property
- ------------------------------------------------
Property                    (pounds)2,999,998
- ------------------------------------------------
Stock/Work in               as determined under
Progress                    Clause 8
================================================


                                     Part 2

                                 Excluded Assets


1.     Cash;

2.     All Finished Products;

3.     The rights to use the name Glaxo, Wellcome, Glaxo Wellcome or their
       respective logos;


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


4.     Any amounts recoverable by members of the Vendor's Group in respect of
       Tax and VAT allowances and repayments attributable to matters or events
       occurring on or before Completion;

5.     The benefit of any insurance claims arising prior to Completion in
       relation to the Business save where such claims relate to Assets to be
       acquired by the Purchaser under this agreement; and

6.     All Book Debts.

7.     All intellectual property in respect of the products manufactured at any
       time at the Property by any member of the Vendor's Group.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                                   SCHEDULE 2

                                  The Property

(In the First Place) (Primo) ALL and WHOLE the Farm of Waterfoot, Annan, part of
the Estate of Newbie in the County of Dumfries extending to one hundred and
sixty two acres and one hundred and forty three decimal or one thousandth parts
of an acre or thereby being the subjects described in and disponed by and
delineated and shown within red lines on the plan annexed and executed as
relative to the Disposition by Newbie Estates (in voluntary liquidation) and
David Simpson Carson, the Liquidator thereof, in favor of Newbie Salmon
Fisheries Limited dated Seventh and recorded in the Division of the General
Register of Sasines for the County of Dumfries on Nineteenth both days of
January Nineteen hundred and Fifty five: Together with the foreshore of the
Solway Firth and of the River Annan ex adverso the said subjects: BUT EXCEPTING
ALWAYS from the said subjects the whole of the salmon and other fishing rights
ex adverso the same; (Secundo) ALL and WHOLE that lot or piece of ground
extending to one thousand one hundred and twenty five square yards or thereby
being the south-west corner of the field marked number 847 on the Ordnance
Survey map of the Parish of Annan in the County of Dumfries being the subjects
described in and disposed by and delineated and coloured red on the Plan annexed
and subscribed as relative to the Feu Charter by William Dalziel MacKenzie in
favor of himself and Patrick Alexander Pasley Dirom and another, as Trustees for
behoof of the District Board of the River Annan, dated Third and recorded in the
said Division of the General Register of Sasines on Seventeenth both days of
October Nineteen hundred and Ninety three; (Tertio) ALL and WHOLE that area of
ground in the County of Dumfries on which was erected the subjects known as
Newbie Villa being the subjects described in and disponed by and shown outlined
in red on the excerpt of the Ordnance Survey map annexed and executed as
relative to the Disposition by Newbie Salmon Fisheries (Property) Limited in
favor of Glaxo Properties Limited dated Twenty seventh September and recorded in
the said Division of the General Register of Sasines on Sixteenth December both
months in 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


Nineteen hundred and Seventy six; and (Quarto) ALL and WHOLE that area of ground
in the County of Dumfries being the subjects described in and (in the Second
Place) disponed by and shown coloured blue between the points "E" and "F" on the
plan annexed and executed as relative to the Deed of Servitude (containing
Disposition and Assignation) by the Rt. Hon. John Frederick, Baron Gretton,
David Stewart Bowser and John Gerard Freeman, as Trustees therein mentioned, in
favor of Glaxo Properties Limited dated Third, Fourteenth and Nineteenth July
Nineteen hundred and Seventy eight and recorded in the said Division of the
General Register of Sasines on Eighth April Nineteen hundred and Eighty; (In the
Second Place) ALL and WHOLE that irregular shaped area or plot of ground in the
County of Dumfries extending to two hundred and twenty square metres or thereby
lying to the south-east of Three Trees Road, Newbie, Annan being the area or
plot of ground more particularly described in, disponed (In the First Place) by
and shown delineated in red on Plan A annexed and executed as relative to
Disposition by Northern Engineering Industries Limited in favor of Glaxo
Operations UK Limited dated Eighteenth April and recorded in the said Division
of the General Register of Sasines on Eleventh June both months in Nineteen
hundred and Eighty TOGETHER WITH (One) the whole buildings and other erections
thereon; (Two) the whole parts, privileges, rights and pertinents thereof or
otherwise offering thereto including without prejudice to the foregoing
generality the servitude and other rights granted in favor of the said subjects
or any part thereof in (a) Deed of Servitude granted by Joseph Robinson in favor
of Glaxo Properties Limited dated Seventh and recorded in the said Division of
the General Register of Sasines on Twenty eighth both days of March Nineteen
hundred and Seventy eight; (b) Deed of Servitude granted by Neil Graham in favor
of Glaxo Properties Limited dated Thirty first March and recorded in the said
Division of the General Register of Sasines on Seventh April both months in
Nineteen hundred and Seventy eight; (c) the said Deed of Servitude (containing
Disposition and Assignation) granted by the Rt. Hon. John Frederick, Baron
Gretton, David Stewart Bowser and John Gerard Freeman, as Trustees therein
mentioned, in favor of Glaxo Properties Limited; (d) Grant of Servitude granted
by the Secretary of State for Defence in favor of Glaxochem 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


Limited dated Eighteenth September Nineteen hundred and Eighty four and recorded
in the said Division of the General Register of Sasines on Thirtieth January
Nineteen hundred and Eighty five; and (e) Minute of Agreement and Deed of
Excambion between Royal Ordnance plc, the Trustees of Edward William Brook and
Glaxochem Limited dated Twenty fifth and Thirtieth August and Twenty eighth
October both months in Nineteen hundred and Ninety three and Twenty first March
Nineteen hundred and Ninety four and recorded in the said Division of the
General Register of Sasines for publication and also as in the Books of the
Lords of Council and Session for preservation on Third June Nineteen hundred and
Ninety four; (In the Third Place) ALL and WHOLE (FIRST) that rectangular piece
of ground lying on the right bank of the River Annan and on the north-east side
of Milnby Quarry together with the access road leading thereto comprising part
of area number 0900 in the County of Dumfries on the 1:2500 inch Ordnance Survey
map NY1867 and being the subjects shown delineated black and coloured pink on
the plan annexed and executed as relative to the said Minute of Agreement and
Deed of Excambion among Royal Ordnance plc, the Trustees of Edward William Brook
and Glaxochem Limited dated Twenty fifth and Thirtieth August and Twenty eighth
October both months in Nineteen hundred and Twenty three and Twenty first March
nineteen hundred and ninety four and recorded in the said Division of the
General Register of Sasines on Third June Nineteen hundred and Ninety four and
(SECOND) that oblong area of ground comprising compartment 4404 in the said
County situated on the north-eastern corner of area number 0002 on the 1:2500
inch Ordnance Survey map NY1867 and being the subjects shown delineated black
and coloured pink on the said plan annexed and signed as relative to the said
Minute of Agreement and Deed of Excambion dated and recorded as aforesaid
TOGETHER WITH (One) the whole buildings and erections on the said subjects
including, without prejudice to the foregoing generality, the pump house erected
on the subjects (FIRST) described and the pumping station erected on the
subjects (SECOND) described; (Two) the whole parts, privileges, rights and
pertinents offering to the subjects including, without prejudice to the
foregoing generality, the heritable and irredeemable servitude and other rights
specified in the 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


Disposition by Newbie Estates in favor of the Minister of Supply in trust as
therein mentioned dated Fifth May Nineteen hundred and Forty three and recorded
in the said Division of the General Register of Sasines on Twenty sixth December
Nineteen hundred and Forty four; (Three) entry to the subjects by existing roads
and ways used for that purpose.

Declaring that the various servitude rights constituted in favor of the subjects
above described (In the First Place) by the said five deeds, and any other
servitudes in favor of such subjects which may be constituted by possession,
shall in this agreement and the Schedules thereto be referred to as "the
Servitudes", and the whole heritable subjects above described, under exception
of the Servitudes, shall in the this agreement and the Schedules thereto be
referred to as "the Subjects", declaring that the Subjects shall be deemed to
comprise the whole of the Property under exception only of the Servitudes.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                                   SCHEDULE 3

                  Terms and Conditions of Sale of the Property

1.     EXHIBITION OF TITLE/DELIVERY OF DEEDS

       1.1    The Vendor warrants that no application has been made for
              registration of title to any part of the Property in the Land
              Register.

       1.2    On the Completion Date the Vendor shall deliver to the Purchaser a
              subscribed Disposition in favor of the Purchaser or its nominees,
              which shall if the Purchaser requires have attached to it a
              taxative plan of the Property acceptable to the Purchaser and
              complying with the specific plan requirements of the Keeper as
              published from time to time and a subscribed Deed of Servitude in
              favor of the Purchaser or its nominees in respect of the Water
              Supply in terms of the draft annexed hereto (Annex 3) and shall
              exhibit or deliver a valid and marketable title to the Property
              (including without prejudice to the generality both the Subjects
              and the Servitudes) together with:

              1.2.1  clear Searches in the Register of Sasines for 40 years (or
                     if longer from the date of the prescriptive writ) and in
                     the Register of Inhibitions and Adjudications for the
                     prescriptive period; and

              1.2.2  a Form P16 Report confirming that the Keeper can identify
                     the Property on the relevant Ordnance Survey Sheet, a Form
                     10 Report brought down to a date as near as practicable to
                     the Completion Date disclosing no entries adverse to the
                     Vendor's interest, and such documents or evidence,
                     including a plan or plans, as the Keeper may require to
                     enable the Keeper to issue a Land Certificate or Land
                     Certificates in name of the 


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                     Purchaser or its nominees (as the case may be) as the
                     registered proprietor of the Property (including without
                     prejudice to the generality the Servitudes) and containing
                     no exclusion of indemnity in terms of Section 12(2) of the
                     1979 Act.

       1.3    There will also be delivered by the Vendor to the Purchaser on the
              Completion Date:

              1.3.1  Searches/Reports in the Register of Charges/Mortgage
                     Register and Company File against any company (including
                     the Vendor) having an interest in the Property within the
                     period of 10 years prior to the Completion Date; such
                     Searches/Reports, continued to a date 22 days after the
                     date such company divested itself of its interest in the
                     Property, shall be clear of entries prejudicial to the
                     ability of the Vendor to grant a valid unencumbered title
                     to the Property in name of the Purchaser or its nominees;

              1.3.2  in relation to the document in terms of which any company
                     referred to in paragraph 1.3.1 divested itself of its
                     interest in the Property, evidence that at the time of
                     signature any person bearing to sign that document as a
                     Director or Secretary of such company was such a Director
                     or Secretary, and that any person signing that document on
                     behalf of such company bearing to have been authorized to
                     do so was authorized to do so;


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              1.3.3  in the case of any body corporate (including the granter of
                     said Disposition) having an interest in the Property within
                     the period of 10 years prior to the Completion Date,
                     evidence that, at the time of signature of any document in
                     terms of which such body corporate divested itself of its
                     interest in the Property, all persons signing that document
                     on behalf of such body corporate were authorized to do so
                     whether in their capacity as office holders of such body
                     corporate or otherwise, except where authority so to sign
                     is presumed under the Requirements of Writing (Scotland)
                     Act 1995;

              1.3.4  a subscribed Assignation of the Water Extraction Consents
                     in the form annexed hereto (Annex 2) completed as
                     appropriate;

              1.3.5  Dundas & Wilson's Letter of Obligation in the form annexed
                     hereto (Annex 4) completed as appropriate and duly
                     subscribed;

              1.3.6  any other items required to be delivered on the Completion
                     Date in terms of any other provision of this Schedule 3.

2.     VENDOR'S POST-SETTLEMENT OBLIGATIONS REGARDING TITLE

       2.1    The Vendor shall procure that the Land Certificate(s) to be issued
              to the Purchaser or its nominees (as the case may be) in respect
              of the whole of the Property will disclose no entry, deed or
              diligence prejudicial to the Purchaser's or its nominees' interest
              other than such as are created by or against the Purchaser or its
              nominees or have been disclosed to and accepted by the Purchaser
              in terms of this agreement.


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       2.2    The Vendor shall exhibit or deliver to the Purchaser within twenty
              days of written demand such documentation, evidence and others
              (including plans) as may be requisitioned by the Keeper in
              connection with the registration of the interest of the Purchaser
              or its nominees (as the case may be) in respect of the whole or
              any part of the Property in the Land Register.

3.     THE GRAZING LEASE

       It shall be an essential condition of this agreement that within 21 days
       of the execution thereof the Vendor shall deliver to the Purchaser a
       subscribed statement and undertaking issued by Messrs J.M. & J. Goldie,
       Newbie Mains, Annan as tenant under the Grazing Lease, and each of the
       individual Partners thereof, confirming that their sole entitlement to
       occupy the subjects of the Grazing Lease is in terms of the Grazing
       Lease, and without prejudice to the generality no agricultural tenancy
       has been created in respect of the subjects of the Grazing Lease, either
       by the Grazing Lease or otherwise, and undertaking to remove from the
       subjects of the Grazing Lease on or before 30 November 1997.

4.     APPORTIONMENTS ETC

       The sums due to the Vendor under the Grazing Lease and the Hoddam
       Agreement shall be apportioned between the Vendor and the Purchaser as at
       the Completion Date, and the apportionment in respect of the Hoddam
       Agreement shall be calculated on the basis of a meter reading taken at
       close of business on the day preceding the Completion Date. The Vendor
       shall indemnify the Purchaser fully against any and all liability which
       the Purchaser may incur in relation to any breach of the terms of the
       Grazing Lease or the Hoddam Agreement by the Vendor prior to the
       Completion Date.


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5.     ASSIGNATION OF RIGHTS

       On or prior to the Completion Date the Vendor shall deliver to the
       Purchaser a subscribed assignation in favor of the Purchaser or its
       nominees assigning to the Purchaser all rights which the Vendor shall
       have in respect of the design, construction, manufacture, assembly or
       installation of any buildings, structures, civil engineering or other
       similar works, plant and equipment, machinery and fixtures and fittings
       on or in the Property, along with certified true copies of all
       documentation (or alternatively a warranted statement confirming the
       whole terms and conditions of the contract) on the basis of which any
       such buildings or others were constructed or otherwise as aforesaid,
       together with evidence that any requisite consent to such assignation has
       been granted, and that in the form annexed hereto (Annex 5) (completed as
       appropriate).

6.     THE ACCESS AGREEMENT

       Following Completion the Vendor shall notify the relevant authority of
       the disposal of its interest in the Property as required by Clause FIRST
       of the Access Agreement.


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                                   SCHEDULE 4

                                    Pensions


                            Part 1: Disclosed Schemes

                        The Glaxo Wellcome Pension Scheme
             The Glaxo Wellcome Contracted Out Money Purchase Scheme

                           Part 2: Transfer Provisions

1      Definitions

       1.1    In this Part of this Schedule the following expressions shall have
              the following meanings:

              "Actuary"                          a Fellow of the Institute of
                                                 Actuaries or a Fellow of the
                                                 Faculty of Actuaries in
                                                 Scotland or a firm employing
                                                 such persons;

              "Actuary's Letter"                 the letter from the Vendor's
                                                 Actuary to the Purchaser's
                                                 Actuary dated 10 September 1997
                                                 a copy of which is annexed to
                                                 this Schedule;

              "Adjusted Transfer          (a)    in relation to transfers
                 Requirement"                    Requirement" from the Vendor's
                                                 Scheme in respect of FS
                                                 Benefits, the Pension
                                                 Liabilities multiplied by the
                                                 Timing Adjustment in respect of
                                                 the period from and including
                                                 the Completion Date to but


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                                                 excluding the Due Date; and

                                          (b)    in relation to transfers from
                                                 the Vendor's Scheme in respect
                                                 of MP Benefits an amount
                                                 representing at the Due Date
                                                 the aggregate of the member's
                                                 accounts to which the
                                                 Consenting Members acquire a
                                                 right on ceasing to be in
                                                 pensionable service under the
                                                 Vendor's Scheme at the
                                                 Completion Date;

              "Consenting Members"               means those Transferring
                                                 Members who have submitted
                                                 Transfer Forms to the Vendor's
                                                 Scheme not later than 13 weeks
                                                 after the later of

                                          (a)    being advised by the trustees
                                                 of the Purchasers Scheme of the
                                                 benefits to be provided for
                                                 them in respect of any transfer
                                                 made in respect of them
                                                 pursuant to this Schedule; and

                                          (b)    the Completion Date

                                                 and who do not withdraw such
                                                 consent prior to payment of the
                                                 Transfer Amount;

              "Approval"                         approval by the Board of Inland
                                                 Revenue as an 


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                                                 exempt approved scheme for the
                                                 purposes of Chapter I of Part
                                                 XIV of the Taxes Act;

              "Due Date"                         the first working day one week
                                                 after the satisfaction of the
                                                 last to be satisfied of the
                                                 Transfer Conditions;

              "FS Benefits"                      means the benefits to which a
                                                 Consenting Member is entitled
                                                 or prospectively and
                                                 contingently entitled and which
                                                 are determined on a final
                                                 salary basis under the Vendor's
                                                 Scheme;

              "Independent Actuary"              an Actuary who is nominated by
                                                 the Vendor and the Purchaser
                                                 jointly or, if they cannot
                                                 agree, by the President of the
                                                 Institute of Actuaries on
                                                 application by either the
                                                 Vendor or the Purchaser;

              "MP Benefits"                      means the Benefits
                                                 (disregarding any additional
                                                 voluntary contributions and
                                                 benefits derived from them) to
                                                 which a Consenting Member is
                                                 entitled or prospectively and
                                                 contingently entitled and which
                                                 are determined on a money
                                                 purchase basis under the
                                                 Vendor's Scheme;


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              "Pensionable Salary"               such remuneration of the
                                                 Relevant Employees as in each
                                                 case is pensionable in
                                                 accordance with the governing
                                                 documentation of the Vendor's
                                                 Scheme;

              "Pension Liabilities"              as defined in the Actuary's
                                                 Letter;

              "Pensionable Service"              such service of the Relevant
                                                 Employees as in each case is
                                                 used for the purpose of
                                                 calculating pension benefits
                                                 under the Vendor's Scheme;

              "Purchaser's Actuary"              the Actuary appointed by the
                                                 Purchaser from time to time for
                                                 the purposes of this Schedule;

              "Purchaser's Scheme"               the ChiRex Pension Scheme
                                                 established by an interim trust
                                                 deed dated 5 February 1996 (or
                                                 where the context so requires,
                                                 the trustees for the time being
                                                 of that scheme);

              "Relevant Employees"               those Employees who at
                                                 Completion are active members
                                                 of the Vendor's Scheme;

              "Timing Adjustment"                as defined in the Actuary's
                                                 Letter;

              "Transfer Amount"                  the amount (if any) which the
                                                 Vendor's Scheme pays to the
                                                 Purchaser's Scheme 


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                                                 in respect of the Consenting
                                                 Members;

              "Transfer Conditions"              all of the following:

                                          (1)    the Board of Inland Revenue has
                                                 given its written approval to
                                                 the transfer of assets from the
                                                 Vendor's Scheme to the
                                                 Purchaser's Scheme in respect
                                                 of the Transferring Members and
                                                 that approval still subsists;

                                          (2)    the Vendor's Scheme has
                                                 received the Transfer Forms
                                                 from Consenting Members; and

                                          (3)    the amount of the Pension
                                                 Liabilities has become final
                                                 and binding whether by
                                                 agreement under paragraph 4 or
                                                 following determination of any
                                                 dispute under paragraph 7;

              "Transfer Form"                    means the document (prepared in
                                                 such form as the Vendor and the
                                                 Purchaser shall agree: such
                                                 agreement not to be
                                                 unreasonably withheld or
                                                 delayed) which shall include a
                                                 discharge in favor of the
                                                 Vendor's Scheme which each
                                                 Consenting Member signs
                                                 confirming his request 


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                                                 for or consent to a payment or
                                                 transfer being made from the
                                                 Vendor's Scheme to the
                                                 Purchaser's Scheme for and in
                                                 respect of him and under which
                                                 he exercises his right in
                                                 relation to his cash equivalent
                                                 in accordance with the
                                                 provisions of Part IV of
                                                 Chapter IV of the 1993 Act so
                                                 as to acquire transfer credits
                                                 or other rights under the
                                                 Purchaser's Scheme;

              "Transferring Members"             those Relevant Employees who
                                                 become members of the
                                                 Purchaser's Scheme with effect
                                                 from Completion Date pursuant
                                                 to the offer of membership
                                                 referred to in paragraph 2
                                                 below and whose names shall be
                                                 provided to the Vendor by the
                                                 Purchaser within 28 days of the
                                                 Completion Date;

              "Vendor's Actuary"                 the Actuary appointed by the
                                                 Vendor from time to time for
                                                 the purposes of this Schedule;

              "Vendor's Scheme"                  the Glaxo Wellcome Pension
                                                 Scheme (or, where the context
                                                 so requires, the trustees of
                                                 that scheme);

              "1993 Act"                         the Pension Schemes Act 1993;


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              "1995 Act"                         the Pensions Act 1995


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2      The Purchaser's Scheme

       The Purchaser undertakes to the Vendor that:-

       2.1    the Purchaser shall procure that not later than 14 days after
              Completion Date all Relevant Employees who have not reached their
              retirement date or otherwise ceased to be active members under the
              Vendor's Scheme shall be invited in writing to become members of
              the Purchaser's Scheme with effect from the Completion Date. The
              invitations must be consistent with this Schedule and in this
              respect they shall be subject to the prior approval of the Vendor
              (which shall not be unreasonably withheld or delayed). For the
              avoidance of doubt any Relevant Employee who dies between the
              Completion Date and the date on which the Relevant Employee either
              becomes a member of the Purchaser's Scheme or is deemed under the
              terms of the invitation to have rejected the invitation shall be
              provided with lump sum death in service benefits and survivor's
              benefits as if he or she had been a member of the Purchaser's
              Scheme with effect from the Completion Date;

       2.2    the Purchaser's Scheme shall at the Completion Date either have
              received Approval or be capable of receiving Approval and be a
              scheme to which the Vendor's Scheme can make a transfer payment
              without prejudicing the Approval of the Vendor's Scheme;

       2.3    the Purchaser undertakes that in respect of the Transferring
              Members and their service with the Purchaser from the Completion
              Date benefits will be provided (subject to the terms of the
              Purchaser's Scheme relating to amendment and discontinuance) on
              the same basis as they are provided for other employees of the
              Purchaser under that scheme.


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3      Calculation of the Transfer Requirement

       3.1    Within a period of 2 months following the Completion Date the
              Vendor shall procure that the Vendor's Actuary receives all
              material information under the Vendor's control which is necessary
              to calculate the Pension Liabilities and the Purchaser shall
              procure that the Vendor's Actuary receives all material
              information under the Purchaser's control required to calculate
              the Pension Liabilities;

       3.2    Within a period of 2 months following the receipt by the Vendor's
              Actuary of the complete, true and accurate information required to
              calculate the Pension Liabilities, the Vendor shall procure that
              the Vendor's Actuary calculates the Pension Liabilities and
              submits his results in writing to the Purchaser's Actuary for
              verification by the Purchaser's Actuary together with such
              information as the Purchaser's Actuary may reasonably require for
              the purpose of verifying the Vendor's Actuary's calculations;

       3.3    At the date which is 2 months after the date of receipt by the
              Purchaser's Actuary of details of the calculations described in
              3.2 above the Purchaser's Actuary shall be deemed to have agreed
              to those calculations and to the amount of the Pension Liabilities
              so calculated unless he shall within that time have notified the
              Vendor's Actuary in writing to the contrary;

       3.4    If the Vendor's Actuary and the Purchaser's Actuary cannot agree
              the amount of the Pensions Liabilities within a period of 3 months
              after the date of receipt by the Purchaser's Actuary of details of
              the calculations described in 3.3 above (or such earlier or later
              date as the Vendor and the Purchaser may agree), then either the
              Vendor or the Purchaser may require by notice in writing to the
              other the amount of the Pension Liabilities 


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              to be determined by an Independent Actuary in accordance with
              paragraph 7 below.

4      Payment of the Transfer Requirement and Provision of Benefits

       4.1    The Vendor shall use its reasonable endeavours to procure that the
              Vendor's Scheme shall pay the Adjusted Transfer Requirement to the
              Purchaser's Scheme on or before the Due Date.

       4.2    The Adjusted Transfer Requirement shall be satisfied by the
              transfer of such assets (which may include cash in whole or part)
              as shall be agreed by the Vendor's Scheme and the Purchaser's
              Scheme and in default of agreement shall be in cash.

       4.3    Subject to receipt of the Adjusted Transfer Requirement on the Due
              Date by the Purchaser's Scheme and/or of any payment which falls
              due under paragraph 5 below, the Purchaser will procure that
              benefits are provided for and in respect of the Consenting Members
              under the Purchaser's Scheme in respect of their service prior to
              the Completion Date:

              4.3.1  in relation to the FS Benefits of each Consenting Member,
                     which are of equivalent value overall, in the reasonable
                     opinion of Purchaser's Actuary and on an actuarial basis
                     consistent with that set out in the Actuary's Letter, to
                     those which would have been provided for and in respect of
                     them under the Vendor's Scheme (as in force at the
                     Completion Date) on retirement, death or withdrawal if the
                     Consenting Member had continued in Pensionable Service
                     under the Vendor's Scheme calculated by reference to
                     Pensionable Salary at retirement, death 


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                     or withdrawal but related only to service prior to the
                     Completion Date; and

              4.3.2  in relation to the MP Benefits of each Consenting Member,
                     which are of equivalent value, in the reasonable opinion of
                     Purchaser's Actuary, and on an actuarial basis consistent
                     with that set out in the Actuary's Letter, to the amount
                     transferred in respect of each of them (which Vendor's
                     Actuary shall identify to Purchaser's Actuary) pursuant to
                     para (b) of the definition of Adjusted Transfer
                     Requirement.

       4.4    The Purchaser's Actuary shall certify to the Vendor's Actuary that
              the benefits to be provided by the Purchaser's Scheme comply with
              paragraph 4.3 above.

5      Adjustments to the Transfer Requirement

       5.1    If at the Due Date the Transfer Amount is less than the Adjusted
              Transfer Requirement the Vendor shall (subject to paragraph 5.2
              below) pay, as an adjustment to the consideration, to the
              Purchaser the amount equal to the difference between the Transfer
              Amount and the Adjusted Transfer Requirement less the percentage
              rate of Corporation Tax applying generally on the Due Date
              multiplied by the Timing Adjustment in respect of the period from
              the Due Date to the actual date of payment (such amount being
              known as "the Shortfall") within a period of 5 working days after
              the Due Date.

       5.2    No payment shall be due from the Vendor pursuant to paragraph 5.1:

              5.2.1  if the reason for the Transfer Amount (or part of it) not
                     having been


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                     transferred to the Purchaser's Scheme at the Due Date is
                     the failure of the Purchaser's Scheme, for whatever reason,
                     to accept the whole, or any part of the Transfer Amount, or
                     if the reason is any other reason outside the control of
                     the Vendor's Scheme but, if no payment is due from the
                     Vendor because of any such other reason outside the control
                     of the Vendor's Scheme, payment will become due (in
                     accordance with paragraph 5.1) if, and when, such reason
                     ceases to exist;

              5.2.2  unless the Purchaser undertakes in writing to the Vendor to
                     pay any amount received pursuant to 5.1 above forthwith to
                     the Purchaser's Scheme.

6      Additional Voluntary Contributions

       6.1    Any additional voluntary contributions paid by Consenting Members
              to Vendor's Scheme and all benefits derived therefrom on a money
              purchase basis shall be disregarded for the purposes of this part
              of this Schedule other than this paragraph 6. The Vendor shall use
              its reasonable endeavours to procure that on the Due Date the
              Vendor's Scheme transfers or procures the transfer to the
              Purchaser's Scheme of the amount of any such additional voluntary
              contributions paid by the Consenting Members to the Vendor's
              Scheme together with accumulated interest or bonuses thereon in
              such form (which may include cash in whole or part) as shall be
              agreed by the Vendor's Scheme and the Purchaser's Scheme and in
              default of agreement shall be in cash;

       6.2    The Purchaser shall procure that the Purchaser's Scheme applies
              the amount of such transfer as is described in 6.1 above in the
              provision of additional benefits on a money purchase basis under
              the Purchaser's Scheme for and in respect of 


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              each relevant individual Consenting Member who has paid such
              additional voluntary contributions.

7      Independent Actuary

       Any dispute between Vendor and Purchaser or between Vendor's Actuary and
       Purchaser's Actuary about any matters referred to in this Schedule shall,
       in the absence of agreement, be referred to an Independent Actuary. The
       Independent Actuary will act as an expert and not as an arbitrator. His
       decision will (except in the case of manifest error) be final and
       binding. His expenses will be borne equally by Vendor and Purchaser or as
       he may otherwise direct.

8      Indemnity

       The Purchaser shall indemnify and keep indemnified the Vendor on an
       after-tax basis against all actions, proceedings, reasonable costs,
       claims, damages and reasonable expenses arising from, or in connection
       with, any claim brought against the Vendor by, or on behalf of, a
       Transferring Member on grounds that the benefits provided under the
       Purchaser's Scheme in respect of service after the Completion Date are
       inferior to those provided under the Vendor's Scheme immediately prior to
       the Completion Date.

                               Part 3: Warranties

1      Except under the Disclosed Schemes no agreement, arrangement, custom or
       practice (whether ex-gratia or otherwise) exists whereby the Vendor is
       under any obligation to provide or pay towards the provision of any
       relevant benefits (as defined in Section 612(1) Taxes Act with the
       omission of the exception to that definition) for any Employee or for any
       dependent of any Employee.


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2      In relation to each Disclosed Scheme full details of the Disclosed Scheme
       have been given to the Purchaser including:-

       2.1    true and complete copies of the trust deeds rules and other
              documents containing the provisions currently governing the
              Disclosed Scheme;

       2.2    copies of the booklet issued to employees who are or may become
              members of the Disclosed Scheme and of all announcements or other
              employee literature issued to such employees which detail changes
              to the provisions of the Disclosed Scheme which are not
              incorporated in the Disclosed Scheme's formal governing documents;

       2.3    in relation to a Disclosed Scheme under which some or all of the
              benefits are payable on a final salary basis a copy of the last
              actuarial valuation;

       2.4    a copy of the audited accounts of the Disclosed Scheme for the
              last scheme year;

       2.5    a list of the Disclosed Scheme's active members setting out all
              information required to determine their respective entitlement to
              benefits under the Disclosed Scheme;

       2.6    full details of any exercise of any power or discretion under the
              Disclosed Scheme in relation to the Relevant Employees (as defined
              in Part 2 above) to augment benefits or to provide new or
              additional benefits which would not otherwise be provided or to
              admit to membership any person who would not otherwise be eligible
              for membership;

3      In relation to each Disclosed Scheme under which the amount of the
       benefits payable to or in respect of a member (other than any insured
       lump sum death in service benefits) is based solely on the amount of the
       accumulated contributions made to the Disclosed Scheme 


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       by or in respect of the member together with investment return thereon:-

       3.1    as far as the Vendor is aware no written undertaking or assurance
              has been made or given to any member of the Disclosed Scheme that
              any particular level or amount of benefit (other than insured lump
              sum death in service benefit) will be provided for or in respect
              of them under the Disclosed Scheme; and

       3.2    no contributions due to the Disclosed Scheme have fallen due but
              are unpaid.

4      Neither the Vendor nor any other employer participating in a Disclosed
       Scheme has any liability to make any payment to the Disclosed Scheme
       pursuant to section 75 Pensions Act 1995 (or otherwise) or any
       undischarged liability pursuant to Regulation 3 the Occupational Pension
       Schemes (Deficiency on Winding Up etc) Regulations 1996.

5      Every employee who has been admitted to membership or offered membership
       of a Disclosed Scheme after 31st May 1989 has been admitted to or offered
       admission on terms which comply with the requirements of Part 2 of
       Schedule 6 to the Finance Act 1989 and the substance of such terms have
       been communicated to each such employee in writing.

6      In respect of the Employees the records of each Disclosed Scheme have
       been properly and accurately maintained, there has been no such breach of
       the trusts of any Disclosed Scheme and there are not in respect of any
       Disclosed Scheme any actions suits or claims (other than routine claims
       for benefits) outstanding pending or threatened against the trustees or
       administrator of the Disclosed Scheme or against the Vendor or any other
       employer participating in the Disclosed Scheme and after making
       reasonable enquiries the Vendor is not aware of any circumstances which
       might give rise to any such claims.


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7      Each Disclosed Scheme is approved or capable of approval as an exempt
       approved scheme (within the meaning of Chapter I of Part XIV Taxes Act)
       and there is in force in respect of the employments to which the Glaxo
       Wellcome Contracted Out Money Purchase Scheme relates an appropriate
       contracting-out certificate under the Pension Schemes Act 1993.

8      In respect of the Employees each Disclosed Scheme has been administered
       in accordance with all applicable laws being all relevant statutes and
       subordinated legislation of the Parliament of the United Kingdom and all
       relevant provisions of the law of the European Communities.

9      Other than as revealed in the documents disclosed to the Purchaser
       pursuant to paragraph 2 no undertaking or assurance has been given to any
       of the Employees as to the continuance or introduction of or increase or
       improvement to any benefits under any Disclosed Scheme which the
       Purchaser will be legally required to implement.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                                   SCHEDULE 5

                                   Warranties

1      INFORMATION SUPPLIED

       All information contained in this agreement (other than in relation to
       the Purchaser), all matters contained in the Disclosure Letter, all other
       information relating to the Business given by the Vendor or its
       accountants or solicitors to the Purchaser or its accountants or the
       Purchaser's Solicitors or the Purchaser's Property Solicitors and the
       replies to the Purchaser's due diligence enquiries are true, accurate and
       complete in every respect and there is no fact or matter relating to the
       Business which is known to the Vendor which has not been disclosed in the
       Disclosure Letter which renders any such matters or information untrue,
       incomplete or misleading or the disclosure of which is material to be
       known by a purchaser of the Business and the Assets.

2      CAPACITY

       The Vendor has full power and authority to enter into and perform this
       agreement which constitutes a binding and enforceable obligation on the
       Vendor in accordance with its terms.

3      ACCOUNTS

       3.1    The Accounts have been carved out from the historical books and
              records of GWO as if the site was a stand alone entity and were
              prepared in accordance with the historical cost convention and
              present fairly in all material respects the assets and liabilities
              of the Business as at the Accounts Date and its profits for the
              accounting reference period ended on the Accounts Date and agree
              with the Records of the Business. The Financial Statements do not
              represent UK statutory financial statements as the site is part of
              Glaxo Operations UK Limited.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       3.2    Without limiting the generality of paragraph ? above the Accounts
              disclose all the Assets and either make full provision or reserve
              for or, as appropriate, disclose all liabilities whether actual,
              contingent, unquantified or disputed and all capital commitments
              whether actual or contingent of the Vendor and/or GWO in relation
              to the Business as at the Accounts Date.

       3.3    Any Slow-Moving Stock included in the Accounts has been written
              down appropriately and any Defective, redundant or Obsolete, Stock
              or Stock outside of its Shelf-Life has been wholly written off and
              the value attributed to the remaining Stock and Work in Progress
              does not exceed the lower of cost or net realisable value at the
              Accounts Date.

       3.4    The audited balance sheets and profit and loss accounts of GWO in
              relation to the Business for each of the accounting reference
              periods ended on the Accounts Date complied with the requirements
              of all relevant laws then in force and with all SSAP's and FRS's
              and generally accepted accounting principles of the United Kingdom
              then in force.

       3.5    The rate of depreciation adopted in the audited balance sheets of
              GWO in relation to the Business for each accounting reference
              periods ended on the Accounts Date was sufficient for each of the
              Fixed Assets of the Vendor in relation to the Business to be
              written down to nil by the end of its useful life.

       3.6    Except as stated in the audited balance sheets and profit and loss
              accounts of GWO in relation to the Business for each of the
              accounting reference periods ended on the Accounts Date no changes
              in the policies of accounting have been made therein for any of
              those periods and the method of valuing Stock and Work in Progress
              and the basis of depreciation and amortization adopted has been
              consistent during each of those periods.


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       3.7    The profits shown by the audited profit and loss accounts of GWO
              in relation to the Business for each of the accounting reference
              periods ended on the Accounts Date have not (except as therein
              disclosed) been affected by any extraordinary or exceptional item
              or by any other factor rendering such profits for all or any of
              such periods unusually high or low.

       3.8    The Management Accounts have been prepared in accordance with
              generally accepted accounting policies and accurately state the
              assets and liabilities and turnover and profit before taxation of
              the Business for the period from 31 December 1996 to the last date
              to which management accounts are available prior to Completion.

4      POSITION SINCE  31 DECEMBER 1996

       4.1    Since 31 December 1996:-

              4.1.1  the Business has been carried on in the ordinary and usual
                     course as regards the nature, extent and manner of carrying
                     it on; and

              4.1.2  there has been no deterioration either in the financial or
                     trading position or in the prospects of the Business; and

              4.1.3  there has been no deterioration by reference to the
                     International Active suppliers Production Plan Model in the
                     expected demand for Product to be produced by the Business
                     over the period of 5 years after the Completion Date.

       4.2    Without prejudice to the generality of paragraph 4.1 since 31
              December 1996:-

              4.2.1  neither the Vendor nor GWO has in relation to the Business
                     acquired or disposed of or agreed to acquire or 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


                     dispose of any business or any material asset or assumed or
                     acquired any material liability (including a contingent
                     liability) otherwise than in the ordinary course of
                     business;

              4.2.2  GWO has paid the creditors of the Business in accordance
                     with their respective credit terms and there are no amounts
                     owing by the Vendor/GWO which have been due for more than 6
                     weeks beyond their normal credit terms;

              4.2.3  no debtor relating to the Business has been released by the
                     Vendor on terms that he pays less than the book value of
                     his debt and no debt owing to the Vendor/GWO in relation to
                     the Business has been deferred, subordinated or written off
                     or has proved to any extent irrecoverable and all book
                     debts at the date hereof are good and will be recoverable
                     in full on their respective due dates in the ordinary
                     course;

              4.2.4  neither the turnover nor the expenses (direct or indirect)
                     nor the trading position nor the margin of profitability of
                     the Business shows any material deterioration by comparison
                     with the turnover, expenses, trading position and margin of
                     profitability of the Business for the corresponding period
                     from 31 December 1995 to 31 December 1996;

              4.2.5  no contract or commitment (whether in respect of capital
                     expenditure or otherwise) has been entered into by the
                     Vendor or GWO in relation to the Business which is of an
                     unusual or long term nature or which was entered into


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                     otherwise than in the ordinary course of the Business;

              4.2.6  save in relation to the design and development work which
                     the Purchaser has agreed is necessary at the Property to
                     facilitate the production of ****, neither the Vendor nor
                     GWO has incurred nor agreed to incur any capital
                     expenditure in relation to the Business;

              4.2.7  neither the Vendor nor GWO has reduced or increased the
                     levels of stocks or raw materials and spares and
                     replacement parts in relation to the Business to a material
                     extent and such stocks are adequate for the current needs
                     of the Business.

5      TAXATION

       5.1    Neither the Vendor nor GWO is involved in any dispute with the
              Inland Revenue HM Customs & Excise or other fiscal authority
              concerning any matter which could affect the Business or any of
              the Assets in any way.

       5.2    There is no unsatisfied liability to capital transfer tax or
              inheritance tax attached or attributable to any of the Assets and
              the Assets are not subject to an Inland Revenue charge as
              mentioned in Section 237 Inheritance Tax Act 1984.

       5.3    No person has a power of sale or mortgage or the right to charge
              on any of the Assets in the circumstances mentioned in Section 212
              Inheritance Tax Act 1984.

       5.4    No security has been given over any of the Assets in favour of the
              Commissioners for Customs and Excise under the provisions of
              paragraph 4 of Schedule 11 Value Added Tax Act 1994.


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       5.5    No election has been made and no election will be made on or
              before Completion under paragraph 2 of Schedule 10 Value Added Tax
              Act 1994 in relation to any of the Property.

       5.6    Neither the Vendor nor GWO has received notice of an election
              under paragraph 2 Schedule 10 Value Added Tax Act 1994 from the
              holder of any interest immediately superior to that held by the
              Vendor in respect of any of the Property.

       5.7    None of the Assets is a capital item the input tax on which may be
              subject to adjustment under Part VA Value Added Tax (General)
              Regulations 1985.

       5.8    All documents in the possession or under the control of the
              Vendor/GWO or to the production of which the Vendor/GWO is
              entitled which are necessary to establish the title of the Vendor
              to any Asset and which attract stamp duty in the United Kingdom or
              elsewhere have been properly stamped and no documents are outside
              the United Kingdom which would attract duty if they were brought
              into the United Kingdom.

6      BUSINESS NAME

       The Vendor/GWO does not use any name for any purpose in connection with
       the Business other than its full corporate name.

7      LICENCES AND CONSENTS

       The Vendor and/or GWO has obtained all licences, permissions,
       authorisations and consents required for the proper carrying on of the
       Business (details of which are set out in the Disclosure Letter). All
       such licences, permissions, authorisations and consents are in full force
       and effect and neither the Vendor nor GWO is in breach of any of the
       terms and conditions attached thereto and there are no circumstances
       known to the Vendor which indicate that any of such licences, 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


       permissions authorisations or consents may be revoked or not renewed in
       whole or in part in the ordinary course of events nor are there any
       circumstances known to the Vendor and/or GWO which indicate that
       equivalent licences, permissions, authorisations, or consents on no less
       favourable terms would not be granted to the Purchaser following its
       acquisition of the Business.

8      THE PROPERTY AND ENVIRONMENTAL MATTERS

              Title

       8.1    The Property comprises all the land and premises and heritable
              property and rights owned, occupied or otherwise used by the
              Vendor/GWO in connection with the Business.

       8.2    GWO is the heritable proprietor of the Property and (save to the
              extent (if any) fully disclosed in the Disclosure Letter) no other
              party has any right, title or interest in or to the Property, and
              all plant and equipment and fixtures and fittings on, at, or in
              the Property are the absolute property of GWO, free from any lien
              or encumbrance.

       8.3    GWO has a good and marketable title to the Property free from all
              questions or doubts and (in particular) where GWO or its
              predecessors in title has prior to the date hereof sold off land
              adjoining or near to the Property there were excepted and reserved
              to the Vendor all necessary and appropriate servitudes and other
              rights for the benefit of the Property.

       8.4    Any information contained in the Disclosure Letter as to the terms
              of any leases or licences which have been granted over any part of
              the Property is true and accurate in all material respects.

       8.5    GWO's title has been recorded in the General Register of Sasines,
              but no application has been 


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              made in respect of the Property in the Land Register.

       8.6    The Deeds and Documents comprise all deeds or documents or written
              agreements which constitute, vary or otherwise affect GWO's title
              to the Property.

              Encumbrances

       8.7    The Property is free from any standard security, floating charge
              or other lien or charge or incumbrance securing the repayment of
              monies or other obligation or liability, whether of the Vendor/GWO
              or any other party.

       8.8    The Property is not subject to any liability for the payment of
              any outgoings other than non-domestic rates, water and sewerage
              rates, and insurance premiums.

       8.9    Save as may be disclosed in the Deeds and Documents the Property
              is not subject to any leases, burdens, restrictions, stipulations,
              servitudes, licences, grants, exceptions or reservations,
              overriding interests or other such rights the benefit of which is
              vested in third parties nor any agreement to create the same.

       8.10   Where any such matters as are referred to in Paragraphs 8.7, 8.8
              and 8.9 have been disclosed in the Disclosure Letter the
              obligations and liabilities imposed and arising under them have
              been fully observed and performed in all material respects and all
              payments in respect of them due and payable have been duly paid.

       8.11   The Property is not subject to any agreement or right to acquire
              the same nor any option right of pre-emption or right of first
              refusal and there are no outstanding actions, claims, disputes or
              demands between the Vendor and/or GWO and any 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              other party affecting or in respect of the Property.

       8.12   Save as disclosed in the Disclosure Letter there is no person who
              is in occupation or who has or claims any rights or servitudes of
              any kind in respect of the Property adverse to the interest, right
              or title of the Vendor or GWO therein.

              Planning Matters

       8.13   For the purposes of sub-paragraphs 8.13 to 8.24 (inclusive) of
              this paragraph 8:-

              "the Planning Acts" means

              The Town and Country Planning (Scotland) Act 1997
              The Planning (Listed Buildings and Conservation Areas) (Scotland) 
              Act 1997
              The Planning (Hazardous Substances) (Scotland) Act 1997
              The Planning (Consequences Provisions) (Scotland) Act 1997
              The Planning and Compensation Act 1991

              as the same are from time to time varied or amended and any other
              statute or subordinate legislation relating to planning matters.

       8.14   Each and every use of the Property is the permitted or lawful use
              for the purposes of the Planning Acts and no such use is subject
              to planning conditions of an onerous or unusual nature (including
              any of a personal or temporary nature).

       8.15   Planning permission has been granted or is deemed to have been
              granted for the purposes of the Planning Acts in respect of the
              development of the Property and any subsequent alteration,
              extension or other improvement of the same and no planning
              permission is of a personal or temporary nature or 


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              has been revoked, modified or suspended or is the subject of a
              Court of Session challenge and no application for planning
              permission is either awaiting decision or the subject of any
              appeal.

       8.16   Building warrants and certificates of completion and approvals
              have been obtained in respect of the development of the Property
              and any subsequent alteration extension or other improvement of
              the same.

       8.17   Compliance is being made and has at all times been made in all
              respects with all planning permissions and building warrants for
              the time being in force in relation to the Property and with all
              orders directions and regulations made under the Planning Acts and
              the Building (Scotland) Acts.

       8.18   Save as referred to in the Disclosure Letter no agreements or
              undertakings relating to the Property have been entered into under
              the provisions of:-

              8.18.1 Sections 3A, 8, 16 or 37 of the Sewerage (Scotland) Act
                     1968;

              8.18.2 Sections 14 and 48 of the Roads (Scotland) Act 1968;

              8.18.3 Section 50 of the Town and Country Planning (Scotland) Act
                     1972 or Section 75 of the Town and Country Planning
                     (Scotland) Act 1997;

              or any similar legislation or earlier legislation of the same
              nature ("Statutory Agreements").

       8.19   Compliance is being and has at all times been made with all
              Statutory Agreements relating to the Property.


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separately with the Commission.


       8.20   No part of the Property is listed as being of special historic or
              architectural importance or located in a conservation area nor is
              the Property affected by any tree preservation orders.

       8.21   All development charges, monetary claims and liabilities under the
              Planning Acts or any other such legislation have been discharged
              and no such liability contingent or otherwise is outstanding in
              respect of the Property.

       8.22   No part of the Property is affected or likely to be adversely
              affected by any proposals contained in any structure plan, local
              plan or unitary development plan prepared or in the course of
              preparation in respect of the areas in which the Property is
              situated.

       8.23   All statements made and all information supplied by or on behalf
              of the Vendor or GWO in support of applications lodged for the
              grant of certificates of lawful existing use or development and
              certificates of lawful proposed use or development under the
              Planning Acts in respect of the Property were and remain true and
              accurate in all material respects.

       8.24   No planning contravention notices, breach of condition notices,
              enforcement notices or stop notices have been issued by any local
              planning authority in respect of the Property nor has any other
              enforcement action (including the exercise of any right of entry)
              been taken by any such authority and the Vendor is not aware of
              any circumstances which may lead to the same.

              Statutory Obligations

       8.25   Compliance is being made and has at all times been made with all
              applicable statutory and byelaw requirements with respect to the
              Property and in particular (but without limitation) with


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              requirements as to fire precautions and means of escape in case of
              fire and with requirements under the Public Health Acts, the
              Housing Acts, the Highways and Roads (Scotland) Acts, the Offices
              Shops and Railway Premises Act 1963, the Health and Safety at Work
              etc Act 1974 and the Factory Acts.

       8.26   There is no outstanding and unobserved or unperformed obligation
              with respect to the Property necessary to comply with the
              requirements (whether formal or informal) of any competent
              authority exercising statutory or delegated powers and neither the
              Vendor nor GWO anticipates that the owner of the Property will be
              obliged to incur the expenditure of any substantial sum of money
              within the next two years for such purpose.

       8.27   There are not in force or required to be in force any licences
              whether under the Licensing (Scotland) Act 1976 or otherwise which
              apply to the Property or relate to or regulate any activities
              carried on therein.

              Adverse Orders

       8.28   There are no compulsory purchase notices orders or resolutions
              affecting the Property nor is the Vendor nor GWO aware of any
              circumstances likely to lead to any being made.

       8.29   There are no closing demolition or clearance orders affecting the
              Property nor is the Vendor nor GWO aware of any circumstances
              likely to lead to any being made.

              Condition of the Property

       8.30   The buildings and other structures on the Property are in good and
              substantial repair and fit for the purposes for which they are
              presently used.


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       8.31   The principal means of access to the Property are over roads which
              have been taken over by the local or other highway or roads
              authority and which are maintainable at the public expense and no
              means of access to the Property is shared with any other party nor
              subject to rights of determination by any other party and the
              Vendor and/or GWO has obtained written confirmation from the roads
              authority that all bridges on the normal route for lorry traffic
              between the Property and the A75 Trunk Road (including without
              prejudice to the generality the bridge over the railway line
              leading to the B724 public road) are fit to carry vehicles of at
              least 40 tonnes weight.

       8.32   The Property enjoys the main services of water drainage
              electricity and gas through media located entirely on in or under
              the Property and the passage and provision of such services is
              uninterrupted.

       8.33   No part of the Property is located in an area or subject to
              circumstances particularly susceptible to flooding.

       8.34   No building or structure on the Property has at any time been
              affected by structural damage or electrical defects or by timber
              infestation rising damp or disease.

       8.35   The Property is not affected by past or present mining activity.

       8.36   None of the buildings or other structures on the Property contains
              so far as the Vendor is aware in its fabric any:-

              8.36.1 high alumina cement or concrete;

              8.36.2 calcium chloride cement;

              8.36.3 calcium silicate bricks or tiles;


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confidential treatment. The omitted portions are marked **** and have been filed
separately with the Commission.


              8.36.4 blue asbestos or other asbestos products;

              8.36.5 wood wool slabs in permanent shuttering form;

              8.36.6 crocidolite;

              8.36.7 untreated sea-dredged aggregates;

              8.36.8 alkali re-active aggregates;

              8.36.9 urea formaldehyde;

              8.36.10 vermiculite plaster;

              8.36.11 artificial slates;

              8.36.12 lead based paints;

              8.36.13 concrete curing accelerator;

              or any deleterious substances or any substances not approved by
              the British Standards and Codes of Practice for the time being.

              Insurance

       8.37   The Property is insured in its full reinstatement value and
              against third party and public liability claims to an adequate
              extent.

       8.38   All premiums payable in respect of insurance policies relating to
              the Property which have become due have been duly paid and no
              circumstances have arisen which would vitiate or permit the
              insurers to avoid such policies.


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separately with the Commission.


              The Grazing Lease

       8.39   The Grazing Lease has been validly executed in self-proving form,
              and the subjects thereof are as shown on the plan annexed to the
              Disclosure Letter. The Grazing Lease has not been varied in any
              respect. Neither the Tenant under the Grazing Lease nor any of the
              partners thereof nor any connected person has had any title to
              occupy any part of the Property prior to commencement of the
              Grazing Lease on 15 March 1997. No party is entitled to claim an
              agricultural tenancy in respect of the property or part thereof,
              and the heritable proprietor for the time being of the Property is
              entitled to vacant possession of the subjects of the Grazing Lease
              on 30 November 1997 without requiring to give any notice.

       8.40   Neither the Vendor nor GWO nor the tenant under the Grazing Lease
              either is or has been in breach of the Grazing Lease in any
              respect.

              The Hoddam Agreement

       8.41   The Hoddam Agreement has not been varied in any respect.

       8.42   Neither Hoddam nor GWO are or have been in breach of the Hoddam
              Agreement in any respect.

              The Water Supply

       8.43   At no time has there ever been complaint about or challenge as to
              the entitlement to the Water Supply by any party at any time since
              the Business commenced to make use of the Water Supply.

       8.44   The Vendor has a valid and marketable title to make use of the
              Water Supply without any restriction as to the quantity of water
              (other than implied by common law) and to leave in place 


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              and maintain repair, renew and replace as necessary the Pipeline.

       8.45   At no time has the quantity of water actually available from the
              Water Supply been inadequate for the requirements of the Business
              or to meet the Vendor's obligations under the Hoddam Agreement.

       8.46   Other than Hoddam in terms of Hoddam Agreement, no other party
              makes use of the Water Supply or the Pipeline.

       8.47   The Pipeline has been properly maintained by appropriate
              specialist contractors and the Vendor is aware of no defects in
              the Pipeline or repairs which might be required to the Pipeline.

       8.48   So far as the Vendor or GWO is aware the Pipeline has not been
              damaged by the action of any third party.

       8.49   The Vendor or GWO has in its possession full records showing the
              quantity of water consumed at the Property through the Water
              Supply, and will deliver same to the Purchaser at Completion.

       8.50   Neither the Vendor nor GWO has at anytime been unable to supply to
              Hoddam 1,500,000 gallons of water per day as required by the
              Hoddam Agreement.

       8.51   Neither the Vendor nor GWO has had cause to complain about the
              abstraction of water from the River Annan by any other party.

              Damage to the Property

       8.52   The Property has at no time suffered any damage or encroachment by
              sea or tidal action or flooding by either salt or fresh water.


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       8.53   Neither the Vendor nor GWO has on any occasion suffered any damage
              to the Property or inconvenience to or interruption of the
              Business pursuant to the exercise of any right of access over the
              Property either pursuant to the Access Agreement or otherwise.

              Miscellaneous

       8.54   The Proprietor of the Boilerworks to the north east of the
              Property has not exercised the right conferred in Disposition by
              Northern Engineering Industries Limited in favor of Glaxo
              Properties Limited recorded in said Division of the General
              Register of Sasines on 11 June 1980 to make use of the access road
              forming part of the Property for heavy vehicular traffic.

       8.55   All the burdens and conditions contained in the Deeds and
              Documents or other title deeds of the Property have been complied
              with and, insofar as of a continuing nature, will be complied with
              by the Vendor or GWO at its own expense until the Completion Date.

       8.56   Other than in terms of the Grazing Lease, no part of the Property
              is or has during the period of ownership of occupation by any
              company in the Vendor's Group been leased to or occupied by any
              party (whether lawfully or otherwise) other than the Vendor
              itself.

       8.57   No company in the Vendor's Group, nor so far as the Vendor is
              aware any third party is or has been in dispute with any neighbour
              or other person or authority whomsoever as to the extent or
              boundaries of the Property or any neighbouring property or any
              common liabilities or title conditions affecting, or servitude
              exercisable by or against (including without prejudice to the
              generality of the Servitudes), the Property or its proprietor, or
              otherwise in respect of the 


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              Property except with regard to previous grazing leases which have
              expired and whose tenants have removed and who have no further
              rights in respect of the Property.

       8.58   There are no notices, orders or proposals under the Planning Acts
              or any other public or local statutes or regulations or orders
              made thereunder or proposals or applications for statutory
              consents in relation to development affecting the Property or
              adjacent or nearby land or buildings, and no part of the Property
              or adjacent land is a SSSI or the subject of any other
              conservation, environmental or amenity designation.

       8.59   All buildings, structures, civil engineering or similar works,
              plant and equipment, machinery and fixtures and fittings on or
              comprised in the Property have been designed, constructed,
              manufactured and assembled or installed by suitably qualified and
              experienced persons in implement of written contracts which are in
              the possession of the Vendor (and which will be delivered by the
              Vendor to the Purchaser on the Completion Date), and in accordance
              with all appropriate statutory and other consents, British
              Standards and Codes of Practice, the Purchaser has not had
              occasion to make any claim against any such person, and the Vendor
              and/or GWO (as appropriate) is entitled to assign to the Purchaser
              all rights which the Vendor and/or GWO (as appropriate) shall have
              against any such person, without requiring the consent of any such
              person or other party, and the Vendor and/or GWO (as appropriate)
              holds all appropriate consents, warranties and guarantees in
              respect of any such buildings or others.

       8.60   There are no matters known to the Vendor adverse to the Property
              the disclosure of which is material to be known by a purchaser of
              the Property.


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              Environmental Matters

       8.61   Consents:

              8.61.1 The Vendor and/or GWO (as appropriate) holds (in its name)
                     all authorizations, permissions, consents, licences and
                     agreements necessary to enable it to carry on the Business
                     lawfully and effectively as at the date of this agreement
                     in the places and in the manner in which the Business is
                     now carried on and in particular (but without limitation):
                     to make all relevant abstractions of water; to keep, store
                     or hold all relevant substances whether as raw materials,
                     products or wastes; to carry on all relevant processes; to
                     construct and maintain all relevant buildings, plant and
                     equipment; and to hold, treat, manage, consign and dispose
                     of all waste materials, substances, gases and effluents in
                     the relevant manner and knows of no circumstances which
                     would require additional authorizations, permissions,
                     consents, licences and agreements to be obtained following
                     Completion if the Business was carried on after Completion
                     in the same way and to the same extent as before
                     Completion.

              8.61.2 All such authorizations, permissions, consents, licences
                     and agreements have been lawfully obtained and are in full
                     force and effect.

              8.61.3 No further authorizations, permissions, consents, licences
                     and agreements are necessary to enable the Purchaser to
                     carry on the Business as now or since 31 December 1996
                     conducted.


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              8.61.4 Without prejudice to paragraphs 8.61.1, 8.61.2 and 8.61.3
                     details of all authorizations, permissions, consents,
                     licences and agreements of the types referred to in
                     paragraph 8.61.1 are set out in the Disclosure Letter
                     (including details of the renewal dates).

              8.61.5 The Vendor and each member of the Vendor's Group has in
                     relation to the Business complied at all times in all
                     respects with all conditions attaching to the
                     authorizations, permissions, consents, licences and
                     agreements referred to in paragraph 8.61.1 (whether such
                     conditions are imposed expressly or are implied by law) and
                     there are no circumstances known to the Vendor which would
                     render it impracticable for the Purchaser to comply with
                     those conditions in the future.

              8.61.6 Neither the Vendor nor any member of the Vendor's Group has
                     in relation to the Business received written notice,
                     correspondence or communication in any other form in
                     respect of any of the authorizations, permissions,
                     consents, licences or agreements referred to above
                     revoking, suspending, modifying or varying any of them and
                     there are no circumstances known to the Vendor which might
                     give rise to such notice being received or of any intention
                     on the part of any relevant authority to give any such
                     notice.

       Compliance with environmental protection laws

       8.62   Neither the Vendor nor any member of the Vendor's Group nor any of
              their officers, agents or employees have committed, in relation to
              the 


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              Business or the Property and whether by act or omission, any
              breach of Environmental Laws, and they have conformed at all times
              with all relevant codes of practice, guidance notes, standards and
              other advisory material issued by any competent authority.

       8.63   Neither the Vendor nor any member of the Vendor's Group has in
              relation to the Business or the Property received any notice,
              order or other communication from any relevant authority in
              respect of a failure to comply with any Environmental Laws and
              there are no circumstances which might give rise to such notice,
              order or other communication being received nor is the Vendor
              aware of any intention on the part of any such authority to give
              such notice.

       8.64   Civil liability

              8.64.1 There is no actual or potential liability on the part of
                     the Vendor or any member of the Vendor's Group arising from
                     any activities or operations of the Business or the state
                     or condition of any properties now or formerly owned or
                     occupied by the Vendor or any member of the Vendor's Group
                     in relation to the Business or facilities now or formerly
                     used by the Vendor or any member of the Vendor's Group in
                     relation to the Business and in particular (but without
                     limitation) any such liability in respect of: injury to
                     persons (including impairment of health or interference
                     with amenity); damage to land or personal property;
                     interference with riparian or other proprietary or
                     possessory rights; public or private nuisance; liability
                     for waste or other substances; and damage to or impairment


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                     of the environment including living organisms.

              8.64.2 Neither the Vendor nor any member of the Vendor's Group is
                     in relation to the Business engaged in any litigation,
                     arbitration or dispute resolution proceedings relating to
                     any actual or potential liability in respect of any matter
                     covered by paragraph 8.64.1 and the Vendor is not aware of
                     any such litigation or proceedings pending or being
                     threatened nor is the Vendor aware of any circumstances or
                     facts likely to give rise to such litigation, arbitration
                     or proceedings.

              8.64.3 Neither the Vendor nor any member of the Vendor's Group is
                     subject to any injunction, interdict or similar remedy or
                     order by a court of competent jurisdiction, or to any
                     undertaking given to such court, in respect of matters
                     referred to in this paragraph 8.64.

              8.64.4 No notification has been (or in accordance with the terms
                     of the relevant policies of insurance should have been)
                     made to the Vendor's or GWO's insurers of any matters
                     specified in this paragraph 8.64.

       8.65   Condition of the Property

              8.65.1 No notice or other communication has been received from any
                     relevant authority relating to the physical condition of
                     the Property nor so far as the Vendor is aware is there any
                     circumstance likely to give rise to the


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                     service of any such notice or communication.

              8.65.2 The Property has not been used for the deposit of waste
                     controlled by any legislation during the ownership or
                     occupation of the Vendor or any member of the Vendor's
                     Group and neither the Vendor nor any member of the Vendor's
                     Group is aware of any such use before its ownership or
                     occupation.

       8.66   Internal policy assessments and plans

              8.66.1 Details of all the Vendor's and GWO's statements of
                     corporate environmental policy and operating procedures are
                     set out in the Disclosure Letter.

              8.66.2 The Vendor and any other relevant company in the Vendor's
                     Group have complied with all its statements of corporate
                     environmental policy and operating procedures.

              8.66.3 The Vendor and each other relevant company in the Vendor's
                     has properly carried out and made all such assessments or
                     plans as are required by law in relation to the substances,
                     processes, operations and wastes (including without
                     limitations those relating to hazardous substances,
                     accident hazards, releases to the environment and noise) of
                     the Business; proper records have been kept of such
                     assessments and plans and the Vendor knows of no
                     circumstances which would render such appraisals or plans
                     incorrect or subject to revision.


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              8.67   Any replies given by or on behalf of the Vendor and/or GWO
                     to enquiries before contract raised by or on behalf of the
                     Purchaser relating in any way to the Property are true,
                     complete and accurate in all respects and contain all
                     information known or available to the Vendor's Group in
                     response to the enquiries.

9      ASSETS

       9.1    The Vendor is the legal and beneficial owner having possession of
              and with good and marketable title to all the Assets and all the
              assets required to carry on the Business are included in the sale
              hereunder and are in the possession or under the control of the
              Vendor.

       9.2    None of the Assets is the subject of any Encumbrance.

       9.3    The Vendor has not created any Encumbrance on over or affecting
              any part of the Assets and there is no agreement or commitment to
              give or create any Encumbrance and no claim has been made by any
              person to be entitled to any Encumbrance.

       9.4    All the plant, machinery, equipment and vehicles of the Vendor
              relating to the Business are in good repair and working order and
              have been regularly and properly maintained and no substantial
              repairs are in hand or are necessary and none of the plant,
              machinery, equipment or vehicles is out of date, dangerous (by
              reason of its state of repair), not fit for its purpose,
              unsuitable or in need of renewal or replacement or fails to comply
              with the applicable safety standards.

       9.5    The List of Fixed Plant and the List of Equipment comprise a
              complete and accurate record of all the plant and equipment (with
              a value of(pounds)50,000 or more), machinery, equipment and
              vehicles owned or possessed by the Vendor in relation to the


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              Business and necessary for the continuation of the Business.

       9.6    There are no Assets used in the Business which are not situate at
              the Property.

10     STOCK

       10.1   All the Stock can be used in the Business.

       10.2   The Stock is sufficient for the normal requirements of the
              Business.

       10.3   The Stock is at its normal level having regard to current orders.

11     INSURANCE

       11.1   Full details of all insurance policies effected in relation to the
              Business have been disclosed to the Purchaser and all such details
              are true and correct in all respects and all such insurance
              policies are currently in full force and effect.

       11.2   Neither the Vendor nor GWO has done or omitted to do or suffered
              anything to be done or not to be done which has or might render
              any policies of insurance taken out by it void or voidable or
              which would or might result in an increase in the rate of premiums
              on the said policies and there are no circumstances of which the
              Vendor is aware which would or might give rise to any claim under
              any of such policies of insurance.

       11.3   There is now and has at all times been adequate insurance in
              respect of the Business against fire, accident, damage, injury,
              third party loss (including product liability) loss of profits and
              other risks normally covered by insurance (including such risks as
              companies carrying on the same type of business as the Business
              commonly cover by insurance).


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12     RECORDS

       The records and books of account of the Vendor and GWO relating to the
       Business are duly entered up and contain true, full and accurate records
       of all matters to be dealt with therein and do not contain any material
       inaccuracies or discrepancies. All books and all records and documents of
       the Vendor and GWO relating thereto which are its property are in the
       possession or under the control of a company within the Vendor's Group.

13     CONFIDENTIAL INFORMATION

       13.1   Neither the Vendor nor GWO uses in the Business any processes and
              is not engaged in the Business in any activities which involve the
              misuse of any Confidential Information belonging to any third
              party.

       13.2   The Vendor is not aware of any actual or alleged misuse by any
              person of any of its Confidential Information.

       13.3   Neither the Vendor nor GWO has disclosed to any person any of its
              Confidential Information except where such disclosure was properly
              made in the normal course of the Business and was made subject to
              an agreement under which the recipient was obliged to maintain the
              confidentiality of such Confidential Information and was
              restrained from further disclosing or using it other than for the
              purposes for which it was disclosed by the Vendor or GWO.

       13.4   Confidential Information used by the Vendor or GWO is kept
              strictly confidential and the Vendor and GWO operate and fully
              complies with procedures which maintain such confidentiality which
              confidentiality has not been breached.


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14     INTELLECTUAL PROPERTY

       14.1   The Vendor is the sole unencumbered legal and beneficial owner and
              where registered the sole registered proprietor of all the
              Intellectual Property.

       14.2   The material particulars as to ownership registration (and
              applications therefor) of the Intellectual Property (if any) are
              set out in the Disclosure Letter and such details are complete and
              correct. Such Intellectual Property comprises all Intellectual
              Property which the Purchaser will require in order fully to carry
              on and exploit the Business and deal with the Assets sold and
              purchased hereunder.

       14.3   None of the Intellectual Property is currently being infringed by
              any third party or has been so infringed in the 6 year period
              preceding the Completion Date and no third party has threatened
              any such infringement.

       14.4   Save for those agreements listed in the Disclosure Letter the
              carrying on of the Business as presently constituted does not
              require any licences or consents from or the making of royalty or
              similar payments to any third party and the Vendor is not engaged
              in any activities which and none of the Vendor's processes or
              products infringe any Intellectual Property belonging to any third
              party. All such listed agreements (and each provision thereof) are
              valid and subsisting and not restricted in any way and the Vendor
              is not in breach of any of the provisions thereof.

       14.5   There are no outstanding claims against the Vendor for
              infringement of any Intellectual Property used (or which has been
              used) by it in the Business and no such claims have been settled
              by the giving of any undertakings which remain in force.


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       14.6   There is no Intellectual Property required for the carrying on of
              the Business which is not exclusively used in respect of the
              Business or which is being licensed to the Purchaser.

15     COMPUTER SYSTEMS

       15.1   The Computer Systems have been satisfactorily maintained and have
              the benefit of the maintenance agreements listed in the Disclosure
              Letter or in the Information Technology Services Agreement.

       15.2   Disaster recovery plans are in effect and in the opinion of the
              Vendor's directors are adequate for its present needs to ensure
              that the Computer Systems can be replaced or substituted without
              material disruption to the Business.

       15.3   In the event that any person providing maintenance or support
              services for the Computer Systems ceases or is unable to do so,
              the Vendor has all necessary rights to obtain the source code and
              all related technical and other information to procure the
              carrying out of such services by its own employees or by a third
              party.

       15.4   The Vendor has adequate procedures for its present needs to ensure
              internal and external security of the Computer Systems, including
              procedures for taking and storing, on-site and off-site, back-up
              copies of computer programs and data.

       15.5   None of the records, systems, controls, data or information
              relating to the Business are recorded, stored, maintained,
              operated or otherwise wholly or partly dependent upon or held by
              any means (including any electronic, mechanical or photographic
              processes whether computerized or not) which (including all means
              of access thereto and therefrom) are not under the exclusive
              ownership and direct control of the Vendor.


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16     DATA PROTECTION

       The Vendor and GWO (as applicable) has complied with all relevant
       requirements of the Data Protection Act 1984, in relation to the Business
       including:

       16.1   the data protection principles established in that Act;

       16.2   request from data subject for access to data held by it; and

       16.3   the requirements relating to the registration of data users.


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17     REPAYMENT LIABILITIES

       Neither the Vendor nor GWO has received any notice to repay any monies or
       liabilities which are repayable on demand and no default or event
       entitling any person with or without giving any formal notice and whether
       immediately or after expiry of any notice to demand or accelerate
       repayment appoint a receiver or take any other action to protect his
       security has occurred in relation to any agreement relating to any
       borrowing or indebtedness or security given by the Vendor or GWO in
       relation to the Business.

18     EMPLOYEES

       18.1   None of the Employees has given or received notice terminating his
              employment or will be entitled to give notice as a result of the
              provisions of this agreement.

       18.2   Full particulars of the terms and conditions of employment of all
              the Employees (including without limitation all remuneration
              incentives bonuses expenses and other payments and benefits
              whatsoever payable) are set out in the Disclosure Letter.

       18.3   There is not in existence any contract of employment with
              directors or employees of the Vendor (or any contract for services
              with any individual) relating to the Business which cannot be
              terminated by 3 months' notice or less without giving rise to a
              claim for damages or compensation (other than a statutory
              redundancy payment or statutory compensation for unfair
              dismissal).

       18.4   In relation to each of the Employees (and so far as relevant to
              each of its Excluded Employees and/or former employees) the Vendor
              has:-


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              18.4.1 complied with all obligations imposed on it by Articles of
                     the Treaty of Rome European Commission Regulations and
                     Directives and all statutes regulations and codes of
                     conduct relevant to the relations between it and the
                     Employees or it and any recognized trade union;

              18.4.2 maintained adequate and suitable records regarding the
                     service of each of the Employees;

              18.4.3 complied with all collective agreements and customs and
                     practices for the time being dealing with such relations or
                     the conditions of service of the Employees; and

              18.4.4 complied with all relevant orders and awards made under any
                     statute affecting the conditions of service of its
                     Employees.

       18.5   The Vendor nor any other company in the Vendor's Group is involved
              in any industrial or trade disputes and to the best of the
              Vendor's knowledge information and belief there are no
              circumstances which may result in any industrial dispute involving
              any of the Employees and to the best of the Vendor's knowledge
              information and belief none of the provisions of this agreement
              including the identity of the Purchaser is likely to lead to any
              industrial dispute.

       18.6   There is not outstanding any agreement or arrangement to which the
              Vendor nor any other company in the Vendor's Group is party in
              relation to the Business for profit sharing or for payment to any
              of its employees of bonuses or for incentive payments or other
              similar matters.


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       18.7   Since 31 December 1996 no change has been made in the terms of
              employment by the Vendor of any of the Employees.

       18.8   Save as disclosed in the Disclosure Letter the Vendor nor any
              other company in the Vendor's Group has not entered into any
              recognition agreement with a trade union in respect of the
              Employees nor has it done any act which may be construed as
              recognition.

       18.9   The Vendor and GWO have complied with all recommendations made by
              the Advisory Conciliation and Arbitration Service and with all
              awards and declarations made by the Central Arbitration Committee.

       18.10  There is no agreement, arrangement, scheme or obligation (whether
              legal or moral) for the payment of any pensions, allowances, lump
              sums or other like benefits on retirement or on death or during
              periods of sickness or disablement for the benefit of any of the
              Employees or for the benefit of dependents of such persons save as
              disclosed in the Disclosure Letter.

       18.11  No amounts due to or in respect of any of the Employees (including
              PAYE and national insurance and pension contributions) are in
              arrear or unpaid.

       18.12  No monies or benefits other than in respect of contractual
              emoluments are payable to any of the Employees and there is not at
              present a claim occurrence or state of affairs which may hereafter
              give rise to a claim against the Vendor or GWO arising out of the
              employment or termination of employment of any employee for
              compensation for loss of office or employment or otherwise and
              whether under the Employment Rights Act 1996 Equal 


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              Pay Act 1970, Sex Discrimination Act 1975, Sex Discrimination Act
              1986, Disability Discrimination Act 1995 or any other act or
              otherwise.

19     CONTRACTS

       19.1   There is not outstanding in connection with the Business:-

              19.1.1 any agreement or arrangement between the Vendor or GWO and
                     any third party which the signature or performance of this
                     agreement will contravene or under which the third party
                     will acquire a right of termination or any option as a
                     result of the signature or performance of this agreement;

              19.1.2 any agency, distributorship, marketing, purchasing,
                     manufacturing or licensing agreement or arrangement or any
                     restrictive trading or other agreement or arrangement
                     pursuant to which any part of the Business has been carried
                     on;

              19.1.3 any agreement or arrangement in relation to the Business
                     between the Vendor or GWO and any other company which is a
                     member of the Group;

              19.1.4 any agreement or arrangement entered into by the Vendor or
                     GWO otherwise than by way of bargain at arm's length and in
                     the normal and ordinary course of the Business; or

              19.1.5 any sale or purchase option or similar agreement or
                     arrangement affecting any of the Assets or by which the
                     Vendor or 


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                     GWO is bound in relation to the Business.

       19.2   None of the Contracts contain are unprofitable (that is to say
              known to have been likely to result in a loss to the Vendor on
              completion of performance if the Vendor had not sold the Business)
              or of a long term nature (that is to say incapable of performance
              in accordance with its terms within 6 months after the date on
              which it was entered into or undertaken).

       19.3   No party with whom the Vendor or GWO has entered into any
              agreement or arrangement in connection with the Business is in
              default thereunder being a default which would have a material and
              adverse effect on the financial or trading position or prospects
              of the Business and so far as the Vendor is aware there are no
              circumstances likely to give rise to such a default.

       19.4   Neither the Vendor nor GWO has any knowledge of the invalidity of
              or grounds for rescission, avoidance or repudiation of any of the
              Contracts and has not received notice of intention to terminate
              any of the Contracts.

       19.5   Neither the Vendor nor GWO has any reason to believe that any
              supplier of the Vendor or GWO or other person dealing with the
              Vendor or GWO in connection with the Business will refuse to deal
              with the Purchaser in connection with the Business or will deal
              with it on a smaller scale than with the Vendor or GWO as a result
              of the signature or performance of this agreement.

       19.6   Details of all tenders which have been made by the Vendor or GWO
              in connection with the Business and which have not yet been
              accepted but are capable of acceptance are contained in the
              Disclosure Letter.


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20     BORROWINGS

       Except as disclosed in the Accounts neither the Vendor nor GWO has
       outstanding in connection with the Business:-

       20.1   any borrowing or indebtedness in the nature of borrowing including
              any bank overdrafts liabilities under acceptances (otherwise than
              in respect of normal trade bills) and acceptance credits other
              than borrowing or indebtedness arising in the ordinary course of
              business;

       20.2   any guarantee indemnity or undertaking (whether or not legally
              binding) to procure the solvency of any person or any similar
              obligation; or

       20.3   any mortgage charge lien pledge or any obligation (including a
              conditional obligation) to create a mortgage charge lien or
              pledge.

21     LITIGATION OFFENCES AND COMPLIANCE WITH STATUTES

       21.1   Neither the Vendor nor any other company in the Vendor's Group is
              plaintiff, defendant (save where it has no knowledge any
              proceedings to be served on it) pursuer or defender or otherwise a
              party to any litigation, arbitration or administrative proceedings
              in connection with the Business which are in progress or are
              threatened or pending by or against or concerning the Vendor or
              any of the Assets the Vendor is not being prosecuted for any
              criminal offence in connection with the Business, no governmental
              or official investigation or inquiry concerning the Business or
              any of the Assets is in progress or pending and so far as the
              Vendor is aware there are no circumstances which are likely to
              give rise to any such proceedings, investigation or inquiry.

       21.2   Neither the Vendor nor any other company in the Vendor's Group nor
              any of its officers, employees 


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              or, so far as the Vendor is aware, its agents (during the course
              of their duties in relation to the Business) has committed or
              omitted to do any act or thing the commission or omission of which
              is or could be in contravention of any statutory obligation or any
              other law of the United Kingdom or any part thereof or any other
              country giving rise to any fine, penalty, default, proceedings or
              other liability in relation to the Business or any of the Assets
              or any judgment or decision which would materially affect the
              financial or trading position or prospects of the Business.

       21.3   Neither the Vendor nor any other company in the Vendor's Group has
              done or agreed to do anything as a result of which either any
              investment or other grant paid to the Vendor in relation to the
              Business is or may be liable to be refunded in whole or in part or
              any such grant for which application has been made by it will or
              may not be paid or may be reduced.

       21.4   There is not outstanding in relation to the Business any liability
              for industrial training levy or for any other statutory or
              governmental levy or charge.

22     RESTRICTIVE AGREEMENTS

       22.1   There are no agreements in force to which the Vendor nor any other
              company in the Vendor's Group is a party directly or indirectly
              affecting the Business which would restrict the freedom of the
              Purchaser to provide and take goods and services by such means and
              from and to such persons as it may from time to time think fit.

       22.2   Neither the Vendor nor any other company in the Vendor's Group is
              nor has it been party to any agreement, arrangement, concerted
              practice or course of conduct directly or indirectly affecting the
              Business which:-


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              22.2.1 is or ought to be or ought to have been or requires to be
                     registered under the Restrictive Trade Practices Acts 1976
                     and 1977 or contravenes the provisions of the Resale Prices
                     Act 1976 or is or has been the subject of any inquiry,
                     investigation or proceeding under any of these Acts;

              22.2.2 is or has been the subject of an inquiry, investigation,
                     reference or report under the Fair Trading Act 1973 (or any
                     previous legislation relating to monopolies or mergers) or
                     the Competition Act 1980; or

              22.2.3 contravenes Article 85(1) or 86 of the Treaty of Rome or
                     which has been notified to the Commission of the European
                     Community for an exemption or in respect of which an
                     application has been made to the said Commission for a
                     negative clearance or infringes any regulation or other
                     enactment made under Article 87 of the said Treaty or is or
                     has been the subject of any inquiry, investigation or
                     proceeding in respect thereof;

              22.2.4 has or is intended to have or is likely to have the effect
                     of restricting, distorting or preventing competition in
                     connection with the production, supply or acquisition of
                     goods in the United Kingdom or any part of it or the supply
                     or securing of services in the United Kingdom or any part
                     of it.

              22.2.5 is by virtue of its terms or by virtue of any practice for
                     the time being carried on in connection therewith a
                     "Consumer Trade Practice" within the 


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                     meaning of section 13 of the Fair Trading Act 1973 and
                     susceptible to or under reference to the Consumer
                     Protection Advisory Committee or the subject matter of a
                     report to the Secretary of State or the subject matter of
                     an Order by the Secretary of State under the provisions of
                     Part II of that Act; or

              22.2.6 infringes any other competition, anti- restrictive trade
                     practice, anti-trust or consumer protection law or
                     legislation applicable in the United Kingdom or elsewhere
                     and not specifically mentioned in this paragraph.

       22.3   Neither the Vendor nor any other company in the Vendor's Group has
              in connection with any matter directly or indirectly affecting the
              Business given any assurance or undertaking to the Restrictive
              Practices Court or the Director General of Fair Trading or the
              Secretary of State for Trade and Industry or the Commission or the
              Court of Justice of the European Communities or any other court,
              person or body and is not subject to any act, decision, regulation
              or other instrument made by any of them relating to any matter
              referred to in this sub-paragraph 24.3.

       22.4   Neither the Vendor nor any other company in the Vendor's Group is
              in default or in contravention of any article, act, decision,
              regulation or other instrument or of any undertaking relating to
              any matter referred to in sub-paragraph 23.2 ("the Anti-Trust
              Rules") and has received no complaint or threat to complain under
              or referring to the Anti-Trust Rules from any person and has not
              received any request for information, investigation or objection
              relating to the Anti-Trust Rules or been party to any proceedings
              to 


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              which the Anti-Trust Rules (or any of them) were pleaded or relied
              upon.

       22.5   Neither the Vendor nor any other company in the Vendor's Group is
              in relation to the Business in a dominant position in any market
              in any substantial part of the EEC for the purposes of Article 86
              of the Treaty of Rome.

23     EFFECTS OF THIS AGREEMENT

       Neither this agreement nor completion thereof:-

       23.1   conflicts with or will or may result in the breach of or
              constitute a default under or give rise to any right of
              termination or acceleration of payment or additional liability
              under any agreement, instrument, order, judgment, award,
              injunction, decree or regulation or any restriction of any kind to
              which a member of the Vendor's Group is a party; nor

       23.2   will or may relieve any other party to any of the Contracts of its
              obligations thereunder or enable it to determine such obligations
              or any of them to the Purchaser's detriment or to the detriment of
              the Business.

24     DEFECTIVE PRODUCTS

       Neither the Vendor nor any member of the Vendor's Group has in relation
       to the Business sold or supplied prior to Completion any products which
       are or were in any respect faulty or defective or which do not comply
       with any warranties or representations expressly or implied made.

25     REORGANIZATION

       Details of the transfer in 1995 of the Business and associated assets
       from Glaxochem Limited to GWO and in 


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       1997 from GWO to the Vendor are contained in the Disclosure Letter.


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                                   SCHEDULE 6

                        Limitations to Vendor's Liability


1       The provisions of this Schedule shall operate to limit the liability of
        the Vendor under the warranties contained in Schedule 5 and references
        to "liability" or "liabilities" shall be construed accordingly.

2       The Vendor shall not be liable for any claim in respect
        of any Relevant Claim:

        2.1      unless the aggregate amount of all Relevant Claims
                 for which the Vendor would otherwise be liable
                 exceeds (pounds)100,000;

        2.2      to the extent that the total liability of the
                 Vendor in respect of all Relevant Claims would
                 exceed ****;

        2.3      unless the Purchaser has given the Vendor written
                 notice of the Relevant Claim (stating in
                 reasonable detail the nature of the Relevant Claim
                 and, if practicable, the amount claimed) on or
                 before the date which is 30 days after the date of
                 receipt of the audited accounts of the Purchaser
                 for the financial period ended 31 December 1999.

        If the aggregate amount of the Relevant Claims exceeds (pounds)100,000
        the Vendor shall be liable for the full amount and not just the excess
        above (pounds)100,000.

3      A Relevant Claim notified in accordance with paragraph 2.3 and not
       satisfied, settled or withdrawn is unenforceable against the Vendor, on
       the expiry of twelve (12) months starting on the day of notification of
       the Relevant Claim unless proceedings in respect of the Relevant Claim
       have been issued and served on the Vendor.


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4      The Vendor shall not be liable in respect of a Relevant Claim:

       4.1    if and to the extent that the matter giving rise to the Relevant
              Claim would not have arisen but for the passing of, or a change
              in, after the date of Completion a law, regulation or
              administrative practice of a government, government department,
              agency or regulatory body, in each case not actually or
              prospectively in force at the date of this agreement;

       4.2    if and to the extent that the matter giving rise to the Relevant
              Claim is an amount for which the Purchaser's Group has recovered
              from any person (other than the Vendor), whether under a provision
              of applicable law, insurance policy or otherwise;

       4.3    if and to the extent that the matter giving rise to the Relevant
              Claim would not have arisen but for an act omission or transaction
              of the Purchaser or an officer of the Purchaser which was outside
              the ordinary course of the Business which it or he should
              reasonably have known would give rise to such liability.

5      The Purchaser shall not be entitled to recover more than once in respect
       of the same loss.

6      The Purchaser shall as soon as reasonably practicable give written notice
       to the Vendor of any matter which it becomes aware which is likely to
       give rise to a Relevant Claim and whether the Purchaser considers it may
       have any remedy against any third party and shall consult with the Vendor
       in respect to the matter. If the Purchaser fails, for whatever reason, to
       comply with the terms of this clause any such failure shall not affect
       the Purchaser's ability to make a Relevant Claim.

7      If the Purchaser becomes aware of a matter which might give rise to a
       Relevant Claim and if such claim is as a 


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       result of or in connection with a claim by or a liability to a third
       party:

       7.1    the Purchaser shall (subject to any obligations as to
              confidentiality to third parties) provide to the Vendor and its
              advisors reasonable access, by prior arrangement, to premises and
              personnel and to relevant assets, documents and records within the
              power or control of the Purchaser's Group for the purposes of
              investigating the matter and enabling the Vendor to take the
              action referred to in paragraph 7.4;

       7.2    the Vendor (at its cost) may by prior arrangement take copies of
              the documents and records and photograph the premises or assets
              referred to in paragraph 7.2;

       7.3    the Purchaser shall (save where any such action would be
              prejudicial to the Business) take any action and institute any
              proceedings and give any information and assistance, as the Vendor
              may reasonably request to dispute, resist, appeal, compromise,
              defend, remedy, settle or mitigate the matter or enforce against a
              person, (other than a member of the Vendor's Group) the rights of
              the Purchaser in relation to the matter in connection with
              proceedings related to the matter (other than against a member of
              the Vendor's Group) and the Vendor shall indemnify the Purchaser
              for all reasonable costs incurred as a result of any such request
              by the Vendor;

       7.4    the Purchaser shall not, and shall ensure that no member of the
              Purchaser's Group will, admit liability in respect of, compromise
              or settle the matter without the prior written consent of the
              Vendor (not to be unreasonably withheld or delayed).

8      If the Vendor pays to the Purchaser an amount in respect of a Relevant
       Claim and the Purchaser or any 


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       member of the Purchaser's Group subsequently recovers from a third party
       an amount which is referable to the matter giving rise to the Relevant
       Claim then:

       8.1    if the amount paid by the Vendor in respect of the Relevant Claim
              is more than the sum recovered from the third party, the Purchaser
              shall as soon as practicable pay the Vendor the sum so recovered;
              and

       8.2    if the amount paid by the Vendor in respect of the Relevant Claim
              is less than or equal to the sum recovered from the third party,
              the Purchaser shall as soon as practicable pay the Vendor an
              amount equal to the amount paid by the Vendor;

9      For the purposes of this paragraph the "sum recovered" means an amount
       equal to the amount recovered from the third party less all reasonable
       costs and expenses incurred by the Purchaser or any member of the
       Purchaser's Group in recovering the amount from the third party.

10     Nothing in this part of this Schedule restricts or limits the Purchaser's
       general obligations to mitigate any loss or damage which it may incur in
       consequence of a matter giving rise to a Relevant Claim.


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