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                            DATED 30th OCTOBER, 1997


                            CHIREX (HOLDINGS) LIMITED
                                   as Borrower


                                   CHIREX INC.
                             CHIREX (DUDLEY) LIMITED
                             CHIREX (ANNAN) LIMITED
                                  as Guarantors


                         BANKERS TRUST INTERNATIONAL PLC
                                MIDLAND BANK PLC
                               as Joint Arrangers


                              BANKERS TRUST COMPANY
                                    as Agent


                              BANKERS TRUST COMPANY
                                as Security Agent


                                       and


                          THE LENDERS DESCRIBED HEREIN

                          ----------------------------

                              FACILITIES AGREEMENT

                                 GBP 62,000,000
                          ----------------------------


                              O'MELVENY & MYERS LLP
                               10 Finsbury Square
                                 London EC2A 1LA

                              Tel: +44 171 256 8451
                              Fax: +44 171 638 8205
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                                TABLE OF CONTENTS

1.   INTERPRETATION............................................................3

2.   THE FACILITIES...........................................................28

3.   PARTICIPATION OF LENDERS.................................................29

4.   CONDITIONS PRECEDENT.....................................................33

5.   DRAWDOWN PROCEDURES......................................................36

6.   REPAYMENT OF ADVANCES....................................................38

7.   PREPAYMENT...............................................................39

8.   INTEREST.................................................................42

9.   PAYMENTS.................................................................45

10.  CHANGE IN CIRCUMSTANCES..................................................48

11.  FEES, EXPENSES AND STAMP DUTIES..........................................51

12.  REPRESENTATIONS AND WARRANTIES...........................................53

13.  UNDERTAKINGS.............................................................61

14.  EVENTS OF DEFAULT........................................................78

15.  GUARANTEE................................................................83

16.  THE AGENT AND THE OTHER FINANCE PARTIES..................................86

17.  EVIDENCE OF INDEBTEDNESS.................................................93

18.  APPLICATION OF MONEYS....................................................93

19.  PRO RATA PAYMENTS........................................................94

20.  SET-OFF..................................................................95

21.  NOTICES..................................................................95

22.  NO IMPLIED WAIVERS.......................................................96

23.  INVALIDITY OF ANY PROVISION..............................................96

24.  CONFIDENTIALITY..........................................................96

25.  CHANGES TO PARTIES.......................................................96


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26.  LENDER DECISIONS.........................................................99

27.  INDEMNITIES..............................................................99

28.  CERTIFICATES CONCLUSIVE.................................................101

29.  GOVERNING LAW...........................................................101

30.  JURISDICTION............................................................101

31.  COUNTERPARTS............................................................102


SCHEDULE 1
     Commitments and Lending Offices......................................S1 - 1

SCHEDULE 2
     Repayment Schedule...................................................S2 - 1

SCHEDULE 3
     Form of Drawdown Request.............................................S3 - 1

SCHEDULE 4
     Structure of ChiRex Group............................................S4 - 1

SCHEDULE 5
     Calculation of the Mandatory Liquid Asset Costs
         for any Sterling Advances........................................S5 - 1

SCHEDULE 6
     Form of Deed of Accession............................................S6 - 1

SCHEDULE 7
     Form of Transfer Certificate.........................................S7 - 1
     First Schedule to the Transfer Certificate...........................S7 - 4
     Second Schedule to the Transfer Certificate..........................S7 - 5

SCHEDULE 8
     Continuing Indebtedness..............................................S8 - 1


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                                                                   Executed Copy
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THIS AGREEMENT ("Agreement") is made on 30th October, 1997

AMONG:-

(1)    CHIREX (HOLDINGS) LIMITED, a limited company organised under the laws of
       England with registered number 3080257 with its registered office at
       Dudley, Cramlington, Northumberland NE23 7QG;

(2)    CHIREX INC., a corporation organised under the laws of the State of
       Delaware with its principal office at 300 Atlantic Street, Suite 402,
       Stamford, CT 06901, U.S.A., CHIREX (DUDLEY) LIMITED., a limited company
       organised under the laws of England with registered number 857670 with
       its registered office at Dudley, Cramlington, Northumberland NE23 7QG,
       and CHIREX (ANNAN) LIMITED., a limited company organised under the laws
       of England with registered number 3417229 with its registered office at
       Dudley, Cramlington, Northumberland NE23 7QG;

(3)    BANKERS TRUST INTERNATIONAL PLC and MIDLAND BANK PLC, as Joint Arrangers;

(4)    BANKERS TRUST COMPANY, as Agent;

(5)    BANKERS TRUST COMPANY, as Security Agent; and

(6)    THE LENDERS DESCRIBED HEREIN.

IT IS AGREED as follows:-

1.     INTERPRETATION

1.1    Definitions

       In this Agreement, unless the context requires otherwise, the following
       expressions shall have the following meanings:-

       "Accountants' Report" means the reports prepared by Arthur Andersen
       relating to analysis of costs of certain operations in the U.K. of the
       ChiRex Group, together with the letter in respect thereof dated 16th
       October, 1997, each addressed to and for the benefit of, inter alia, the
       Finance Parties;

       "Achievement Date" means the later of (i) 31st December, 1998 or (ii) the
       first Accounting Quarter end following the date of this Agreement as at
       which the Total


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       Debt/EBITDA Ratio, calculated as provided in Clause 13.4, is 2:1 or
       lower;

       "Accounting Quarter" means, subject to Clause 13.3, each successive
       fiscal period of the ChiRex Group consisting of three consecutive months;

       "Accounting Reference Period" means each successive financial year of the
       ChiRex Group ending on or about 31st December, as such ending date may be
       altered in accordance with Clause 13.3;

       "Advance" means the principal amount of the borrowing made or to be made
       by the Borrower on a Drawdown Date under any of the Facilities (and
       includes a WCP Advance) or, as the context requires, the principal amount
       thereof for the time being outstanding;

       "Advisory Capacity" has the meaning given to it in Clause 16.6.3;

       "Affected Interest Period" has the meaning given to it in Clause 8.5.1;

       "Affected Lender" has the meaning given to it in Clause 10.1.1;

       "Agency Indemnitees" has the meaning given to it in Clause 16.8.1;

       "Agent" means Bankers Trust Company acting in its capacity as agent for
       the Lenders or such other agent for the Lenders as shall be appointed
       pursuant to Clause 16.9;

       "Annan Facility" means the manufacturing facility situated at Annan,
       Dumfries, Scotland to be purchased pursuant to the Sale and Purchase
       Agreement;

       "Annan Note" means the note dated the date hereof to be issued by ChiRex
       (Annan) Limited to the Borrower in respect of the proceeds of the Tranche
       A Facility;

       "Approved Accounting Principles" means (a) with regard to the Borrower,
       ChiRex (Dudley) Limited, and ChiRex (Annan) Limited, accounting
       principles and practices generally accepted in the U.K. consistently
       applied and (b) with regard to ChiRex Inc. and ChiRex America Inc.,
       accounting principles generally accepted in the U.S. consistently
       applied;


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       "Assets" has the meaning set forth in the Sale and Purchase Agreement;

       "Auditors" means Arthur Andersen, or such other firm of accountants as
       the Borrower may appoint in compliance with the provisions of Clause
       13.3.3;

       "Availability Period" means the period commencing on the Initial Drawdown
       Date and ending on the earlier of (i) the fifth day thereafter and (ii)
       the date on which the Commitments are terminated in full;

       "Available Amount" means, at any time, the lesser of (i) 50% of the
       cumulative Net Income of the ChiRex Group or (ii) 50% of the cumulative
       Cashflow of the ChiRex Group, in each case calculated for each successive
       Accounting Reference Period or part thereof beginning on the date of this
       Agreement and ending on the last day of the Accounting Reference Period
       ending immediately prior to such time, and in each case after making
       appropriate deduction in respect of any Accounting Reference Period in
       which Net Income or Cashflow, as the case may be, is negative;

       "Available Currency" means (a) in respect of the Tranche A Facility, GBP
       only and (b) in respect of the Tranche B Facility, DEM, FF, LIT, GBP,
       CHF, Yen and USD and, subject to the provisions of Clause 5.1.7, any
       other currency freely available to all the Lenders in which dealings
       regularly occur in the London interbank market, provided that the Agent
       has, prior to selection of such currency, confirmed such availability to
       the Borrower;

       "Borrower" means ChiRex (Holdings) Limited;

       "Business" means the business of ChiRex Inc. and its subsidiaries as
       described in ChiRex Inc.'s Form 10-K with respect to its fiscal year most
       recently ended;

       "Business Day" means, in respect of each Available Currency, a day (other
       than a Saturday, Sunday or public holiday) which is a day on which banks
       are open for dealings in such Available Currency in the London interbank
       market and on which banks are open for business (and are not permitted by
       law to remain closed) in the place where the main domestic market for
       such Available Currency is situated;

       "Business Plan" means a set of five year financial projections, together
       with the assumptions forming the


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       basis thereof, prepared in connection with the execution and delivery of
       this Agreement by the management of ChiRex Inc. in respect of the
       consolidated operations of ChiRex Inc. and its subsidiaries, which
       Business Plan shall include the initial Operating Budget;

       "Capital Expenditure" means in relation to a person or group of persons,
       expenditure treated as expenditure in respect of tangible fixed assets in
       accordance with the applicable Approved Accounting Principles and
       determined for such person or, on a consolidated basis, for such persons
       (as the case may be);

       "Cashflow" means, in respect of the relevant testing period in relation
       to a person or group of persons under the applicable Approved Accounting
       Principles:

       EBITDA, adjusted as follows, to the extent not already similarly treated
       in calculating EBITDA,

            PLUS: (a)   decreases in Working Capital during the relevant period,
                        and losses on fixed asset disposals during the relevant 
                        period;

                  (b)   increases in provisions to the extent not previously
                        taken into account in Working Capital (other than
                        deferred tax provisions);

                  (c)   cash proceeds from the issuance of shares of capital
                        stock in ChiRex Inc. and cash proceeds from any Equity
                        Sale;

                  (d)   cash income constituting extraordinary or exceptional
                        items; and

                  (e)   Net Cash Proceeds of disposals during the relevant
                        period, if positive;

           MINUS: (f)   increases in Working Capital during the relevant period
                        and gains on fixed asset disposals during the relevant
                        period;

                  (g)   Capital Expenditure paid during the relevant period
                        which expenditure is (i) in accordance with the Business
                        Plan, or (ii) pursuant to the prior written consent of
                        the Agent;

                  (h)   Tax paid during the relevant period;


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                  (i)   Total Debt Service, to the extent paid in cash, in
                        respect of (i) Financial Indebtedness under the Finance
                        Documents, (ii) Continuing Indebtedness, and (iii)
                        Permitted Indebtedness falling within paragraph (iii) or
                        (x) of the definition thereof;

                  (j)   the sum of prepayments pursuant to Clauses 7.1 (to the
                        extent applied pursuant to the provisions hereof to
                        Tranche A Term Advances only) and 7.3;

                  (k)   cash expenses constituting extraordinary or exceptional
                        items;

                  (l)   decreases in provisions to the extent not previously
                        taken into account in Working Capital (other than
                        deferred tax provisions); and

                  (m)   Net Cash Proceeds of disposals during the relevant
                        period, if negative;

       and determined in accordance with such Approved Accounting Principles for
       such person or, on a consolidated basis, for such persons (as the case
       may be);

       "Change of Control" means (i) ChiRex Inc. shall cease to beneficially own
       and control, directly or indirectly, 100% of the issued and outstanding
       shares of ChiRex America Inc. or the Borrower, or the greater of (A) 75%
       of the issued and outstanding shares of capital stock of any of its other
       subsidiaries or (B) the percentage of ownership necessary for ChiRex Inc.
       to maintain group tax benefits with respect to its other subsidiaries; or
       (ii) any person or any two or more persons acting in concert shall have
       acquired beneficial ownership (within the meaning of Rule 13d-3 under the
       Exchange Act), directly or indirectly, of the equity securities of ChiRex
       Inc. (or other securities convertible into such equity securities)
       representing 50% or more of the combined voting power of all equity
       securities of ChiRex Inc. entitled to vote in the election of director;
       or (iii) any person or any two or more persons acting in concert shall
       have acquired the ability to exercise management control over ChiRex
       Inc.;

       "CHF" means the lawful currency from time to time of Switzerland;


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       "ChiRex (Annan) Limited" means ChiRex (Annan) Limited, a limited company
       organised under the laws of England with registered number 3417229;

       "ChiRex Group" means ChiRex Inc. and each direct and indirect subsidiary
       thereof;

       "ChiRex Inc." means ChiRex Inc., a corporation organised under the laws
       of the state of Delaware;

       "Code" means the United States Internal Revenue Code of 1986;

       "Commitment" means, in relation to the participation of any Lender in a
       Facility, the amount stated opposite its name in Schedule 1 in relation
       to that Facility (or, in the case of a Transferee, the amount stated in
       the Schedule to the relevant Transfer Certificate as being transferred to
       that Transferee), in each case as the same may be transferred (in whole
       or in part), cancelled, reduced, varied or terminated in accordance with
       the terms of this Agreement;

       "Continuing Indebtedness" means financial indebtedness of the ChiRex
       Group identified on Schedule 8, and in each case all interest and other
       amounts accrued thereon during or for the interest period current at any
       date of determination, each such item of financial indebtedness being
       evidenced by its related agreement, deed or other instrument in the form
       in existence on the date of this Agreement, subject to such changes
       therein and refinancings thereof as do not materially prejudice the
       interests of the Finance Parties under or in connection with the Finance
       Documents;

       "Dangerous Substance" means any natural or artificial substance (whether
       in a solid or liquid form or in the form of a gas or vapour and whether
       alone or in combination with any other substance) (i) capable of causing
       harm to man or any other living organism or of damaging the Environment
       or causing danger to public health or welfare, including without
       limitation any hazardous, toxic or dangerous waste, which is subject to
       regulation by any Governmental Authority under any applicable
       Environmental Law, or (ii) because of its quantity, concentration or
       physical or chemical characteristics, exposure to which is limited by any
       applicable Governmental Authority;


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       "Deed of Accession" means one or more deeds to be executed by any obligor
       who becomes an Obligor after the date of this Agreement, substantially in
       the form of Schedule 6, subject to variation in accordance with the laws
       of the jurisdiction of organisation of the relevant Obligor which relate
       to the giving of guarantees and similar undertakings, and with such
       amendments thereto as the Agent may reasonably require or permit;

       "Default Interest Period" has the meaning given to it in Clause 8.4.1.;

       "Default Rate" has the meaning given to it in Clause 8.4.1;

       "DEM" means the lawful currency from time to time of the Republic of
       Germany;

       "Discharged Rights and Obligations" has the meaning given to it in Clause
       25.3.2;

       "Drawdown" means the making of the Advances hereunder;

       "Drawdown Date" means the date for the making of an Advance as specified
       by the Borrower in the relevant Drawdown Request;

       "Drawdown Request" means a notice requesting an Advance in the form set
       out in Schedule 3;

       "Dudley Facility" means the manufacturing facility situated at Dudley,
       Cramlington, Northumberland NE23 7QG, England, owned as of the date of
       this Agreement by ChiRex (Dudley) Limited;

       "Due Diligence Report (Legal)" means, collectively, (i) ChiRex Inc.'s
       Form 10-K with respect to its fiscal year ended 31st December 1996, (ii)
       the report(s) in agreed terms previously compiled by Dibb Lupton Alsop
       regarding the Annan Facility, (iii) the report(s) in agreed terms
       compiled by Brodies WS regarding the Annan Facility, (iv) the report(s)
       in agreed terms compiled by British Geological Survey regarding the water
       supply at the Annan Facility, and (v) the report(s) in agreed terms
       compiled by MacFarlanes regarding the Dudley Facility;

       "EBIT" means, in respect of the relevant testing period and in relation
       to a person or group of persons under the applicable Approved Accounting
       Principles, EBITDA less (i) depreciation on all fixed assets, (ii)
       amortisation


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       of goodwill, acquisition costs and other intangible assets and (iii)
       write-downs, write-offs, minority interests and other non-cash charges in
       determining earnings of such person or persons for that period,
       determined in accordance with such Approved Accounting Principles for
       such person or, on a consolidated basis, for such persons;

       "EBITDA" means, in respect of the relevant testing period and in relation
       to a person or group of persons under the applicable Approved Accounting
       Principles, Net Income for that period, determined in accordance with
       such Approved Accounting Principles for such person or, on a consolidated
       basis, for such persons adding back (if previously deducted) or, as the
       case may be, before any deduction (to the extent that such deduction is
       made in the calculation of earnings) for or on account of:-

       (a)    Total Interest;

       (b)    Tax charged or credited during the relevant testing period;

       (c)    depreciation on fixed assets;

       (d)    amortisation of goodwill, acquisition costs and other intangible
              assets; and

       (e)    write-downs, write-offs, minority interests and other non-cash
              charges in determining earnings of such person or persons for that
              period;

       and excluding the effect, positive or negative, of items which would be
       regarded as extraordinary or exceptional items;

       "Employee Benefit Plan" means, at any time, any "employee benefit plan"
       as defined in Section 3(3) of ERISA and any "multiemployer plan" as
       defined in Section 3(37) of ERISA, to which any US Obligor or any of
       their respective ERISA Affiliates is contributing, or ever has
       contributed, or to which any US Obligor or any of their respective ERISA
       Affiliates has, or ever has had, an obligation to contribute;

       "Environment" consists of all, or any, of the following media: the air,
       water as ground water, surface water, drinking water supplied, vapour and
       ice, and land (both surface and subsurface); and the medium of the air
       includes the air within buildings and air within other


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       natural or manmade structures, above or below ground and "Environmental"
       shall be construed accordingly;

       "Environmental Claim" means (i) any threatened or instituted claim,
       demand, accusation, allegation or notice of violation, in each case made
       in writing, against any Obligor or any of their respective subsidiaries
       (not being a purely vexatious, frivolous or specious claim) by any person
       (x) in respect of any loss or liability suffered or incurred by that
       person as a result or in connection with any violation of Environmental
       Law or (y) giving rise to any remedy or penalty that may be enforced or
       assessed by private or public legal action in connection with
       Environmental Contamination or (ii) any remedial action or action to
       comply that any Obligor or any of their respective subsidiaries is
       obliged to undertake pursuant to Environmental Law in connection with
       Environmental Contamination, or (iii) any application for any interim or
       final judicial or administrative decree, injunction, cease and desist
       order, abatement order, compliance order, consent order, consent decree,
       settlement agreement, request for information, clean-up order or
       enforcement notice, stop notice, improvement notice, prohibition notice
       or revocation order against any Obligor or any of their respective
       subsidiaries in respect of Environmental Contamination;

       "Environmental Contamination" means the following and the consequences
       resulting therefrom: any condition connected with any emission, release,
       leakage, spillage, or presence, use, leaching or migration (in any case
       whenever occurring), of Dangerous Substances at or from any site (or the
       migration of a Dangerous Substance from surrounding property or
       groundwater in, into or onto any site) owned or operated by any Obligor
       or any of their respective subsidiaries, and any residual Dangerous
       Substance on or under any site owned or operated by any Obligor or any of
       their respective subsidiaries including (without limitation) the storage,
       keeping, handling, labeling, transfer or disposal of Dangerous
       Substances, to the extent any of the foregoing results in a breach of any
       Environmental Law or has given or could reasonably be expected to give
       rise to an Environmental Claim;

       "Environmental Event" means any event (whenever occurring) which
       constitutes a breach of any Environmental Law or which has given or could
       reasonably be expected to give rise to an Environmental Claim;


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       "Environmental Law" means all present and future laws, regulations,
       ordinances, permits guidance documents or other requirements having legal
       effect in any jurisdiction in which any Obligor carries on business or
       owns assets, or in the European Union as a whole, concerning the
       protection of the Environment, human health and safety or the control of
       Dangerous Substances;

       "Environmental License" means any permit, license, authorisation, plan,
       consent order or consent decree of or from any Governmental Authority;

       "Environmental Report" means such reports or other documents from the
       Obligors and/or third parties in form and substance satisfactory to the
       Agent to be provided to the Agent in connection with the execution and
       delivery of the Agreement, compiling information relating to compliance
       by the Obligors with, and liabilities of the Obligors under, applicable
       Environmental Laws, including the following documents: (i) Environmental
       Phase I Survey of Annan Facility, dated September 1997, prepared by Dames
       & Moore, (ii) Environmental Phase I Survey of Dudley Facility, dated
       August 1995, prepared by Peter Brett Associates, (iii) Environmental
       Phase I Update of Dudley Facility, dated November 1995, prepared by
       Environmental Resources Management, and (iv) management letter dated 30th
       October, 1997, relating to environmental updates in respect of the Dudley
       Facility;

       "Equity Sale" means the sale or transfer of equity securities in any
       direct or indirect subsidiary of ChiRex Inc., which sale or transfer
       dilutes the aggregate percentage equity ownership (direct or indirect) of
       ChiRex Inc. in such subsidiary;

       "Equivalent Amount" means the amount of a currency other than GBP that
       can be purchased with GBP calculated on the basis of the Agent's spot
       rate of exchange for the purchase of such other currency with GBP on the
       date such calculation is to be made (such calculation to be made, for the
       purpose of determining the amount available to be drawn under the Tranche
       B Multicurrency Revolving Facility, on the Rate Fixing Day applicable to
       the relevant Drawdown Date);

       "ERISA" means the Employee Retirement Income Security Act of 1974, as
       amended from time to time, and any successor statute;


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       "ERISA Affiliate", as applied to any person, means any entity required to
       be treated with any US Obligor as a single employer under Section 414 of
       the Internal Revenue Code;

       "Event of Default" means one of the events specified in Clause 14.1;

       "Exchange Act" means the Securities Exchange Act of 1934, as amended from
       time to time, and any successor statute;

       "Facilities" means the Tranche A Facility and the Tranche B Facility
       (including the WCP Facilities) not in excess of the Total Commitments
       granted to the Borrower hereunder (as the same may be reduced in
       accordance with the terms of this Agreement);

       "Facility Amount" means (i) in the case of the Tranche A Term Facility,
       GBP 40,000,000, and (ii) in the case of the Tranche B Multicurrency
       Revolving Facility, GBP 22,000,000, or the Equivalent Amount thereof, in
       each case as the same may be reduced or cancelled pursuant to the terms
       of this Agreement;

       "Fees Letter" means the letters from ChiRex Inc. to Bankers Trust
       International PLC in the agreed terms setting out details of the fees
       payable pursuant to Clause 11.1.1(b);

       "FF" means the lawful currency from time to time of the Republic of
       France;

       "Final Repayment Date" means the earlier of (a) 31st December, 2002 and
       (b) the date on which the Commitments are terminated in full in
       accordance with the terms of this Agreement;

       "Finance Documents" means this Agreement, the Fees Letter, each WCP
       Agreement, each Transfer Certificate, each Security Document, each Deed
       of Accession and any other document expressed to be made supplemental to,
       amending and/or modifying any of the foregoing or entered into pursuant
       hereto or thereto, and "Finance Document" means any of them;

       "Finance Indemnitees" has the meaning given to it in Clause 27.1;

       "Finance Parties" means each Arranger, the Agent, the Security Agent,
       each Lender and each WCP Provider, and

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       "Finance Party" means any of them; "Financial Indebtedness" means,
       without duplication, any indebtedness in respect of or arising under or
       in connection with:-

       (i)    moneys borrowed including, without limitation, on a contractually
              subordinated basis;

       (ii)   any debenture, bond, note or loan stock or other similar
              instrument;

       (iii)  any acceptance or documentary credit (except, in the case of
              documentary credits, those issued in support only of liabilities
              to trade creditors incurred in the ordinary course of business and
              having a term of not more than 90 days);

       (iv)   receivables sold or discounted in a transaction other than one in
              respect of which (a) no recourse exists against any Obligor and no
              Obligor has any obligation to repurchase, or make any payment in
              respect of deficiencies in collection of, any receivables, and (b)
              no Obligor has the right or obligation to sell, discount or
              otherwise dispose of receivables in addition to those transferred
              on the initial funding date of the transaction;

       (v)    the acquisition cost of any asset to the extent payable after the
              time of acquisition or possession by the person liable as
              principal obligor for the payment thereof where the deferred
              payment is arranged primarily as a method of raising finance or
              financing or refinancing the acquisition of the asset acquired
              (which, for the avoidance of doubt, shall not include liabilities
              to trade creditors incurred in the ordinary course of business and
              having a term of not more than 90 days);

       (vi)   the sale price of any asset to the extent paid before the time of
              sale or delivery by the person liable to effect such sale or
              delivery where the advance payment is arranged primarily as a
              method of raising finance or financing or refinancing the
              manufacture, assembly, acquisition or holding of the asset to be
              sold;

       (vii)  finance leases, credit sale or conditional sale agreements
              (whether in respect of land, buildings, plant, machinery,
              equipment or otherwise) entered into primarily as a method of
              raising finance or financing or refinancing


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              the acquisition of the relevant asset (but not including
              liabilities under operating leases);

       (viii) the amount payable under any put option or other arrangement
              whereby the Borrower or any of its subsidiaries is liable to
              purchase share capital or other securities issued;

       (ix)   any guarantee, indemnity or similar assurance against financial
              loss of any person in respect of obligations of the type described
              in the preceding paragraphs (i) to (viii);

       (x)    any guarantee, endorsement or other undertaking of responsibility
              for any obligations of any other person, whether (a) directly or
              indirectly by agreement to purchase the Financial Indebtedness of
              any other person, or (b) through the purchase of goods or other
              assets, supplies or services, or maintenance of working capital or
              other balance sheet covenants or conditions, or by way of stock
              purchase, capital contribution, advance or loan which, in any case
              in this subclause (b), is entered into for the purpose of paying
              or discharging any Financial Indebtedness of such other person or
              assuring the holder of such Financial Indebtedness or obligation
              against loss in respect thereof;

       (xi)   amounts raised under any other transaction having as a primary,
              and not an incidental effect, the commercial effect of a
              borrowing;

       (xii)  debts incurred in the ordinary course of business which remain
              unpaid for more than 60 days after their due date for payment,
              including for this purpose debts which upon their incurrence are
              within the exceptions set forth in paragraph (iii) above (other
              than debts which are being diligently contested in good faith
              unless the Agent reasonably believes that there is no reasonable
              prospect of success); or

       (xiii) net amounts payable under any interest rate or currency swap,
              collar or other similar agreement or any other hedging or
              derivative instrument, the amount of Financial Indebtedness being
              attributable thereto being 10% of the face or notional amount of
              the relevant agreement, or in each case such lower


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              percentage as shall be reasonably approved by the Agent;

       "GBP" means the lawful currency from time to time of the United Kingdom;

       "Glaxo Group Limited" means Glaxo Group Limited, a company organised
       under the laws of England, whose registered office is at Glaxo Wellcome
       House, Berkeley Avenue, Greenford, Middlesex UB6 0NN;

       "Glaxo Operations UK Limited" means Glaxo Operations UK Limited, a
       company organised under the laws of England, whose registered office is
       at Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex UB6 0NN;

       "Governmental Authority" means any domestic or foreign court or
       governmental body, department, agency, commission, authority or
       instrumentality;

       "Guarantees" means the guarantees by the Guarantors pursuant to Clause
       15;

       "Guarantor" means, together, ChiRex Inc., ChiRex (Dudley) Limited, ChiRex
       (Annan) Limited, and/or other guarantors acceptable to the Lenders;

       "Holdings Note" means the promissory note issued by the Borrower to
       ChiRex Inc. on 30th October 1997 in the principal amount of USD
       38,234,000;

       "ICTA" means the Income and Corporation Taxes Act 1988, as the same may
       be amended from time to time;

       "Industry Report" means the report by Chem. Systems, together with the
       letter in respect thereof, each addressed to and for the benefit of,
       inter alia, the Finance Parties;

       "Information Memorandum" means the document containing information
       relating to the Business prepared in connection with this Agreement by
       the Agent and the ChiRex Group and distributed by the Agent to the
       Lenders and potential Lenders;

       "Initial Drawdown" means the making of the first Advance hereunder, which
       Advance must in any event be an amount sufficient to discharge all fees
       due and payable on the Initial Drawdown Date pursuant to Clause 11.1.1;


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       "Initial Drawdown Date" means the date of the Initial Drawdown, which
       date shall occur on or after each of the conditions set forth in Clause
       4.1 have been satisfied or waived by the Agent, and which date shall
       occur on or before the tenth Business Day after the date of this
       Agreement;

       "Intellectual Property" means all patents and patent applications, trade
       and/or service marks and trade and/or service mark applications (and all
       goodwill associated with such applications), all brand and trade names,
       all copyrights and rights in the nature of copyright, all design rights,
       all registered designs and applications for registered designs, all trade
       secrets, know-how and all other intellectual property rights now or in
       the future owned by any Obligor throughout the world or the interest of
       any Obligor in any of the foregoing now or in the future, together with
       the benefit of all present and future agreements entered into or the
       benefit of which is enjoyed by any Obligor relating to the use or
       exploitation of any of the aforementioned rights;

       "Interest Coverage Ratio" means, at any time, the ratio of (i)
       consolidated EBITDA for the immediately preceding four Accounting
       Quarters, to (ii) Total Interest for the immediately preceding four
       Accounting Quarters, in each case in respect of the ChiRex Group.;

       "Interest Payment Date" means, in relation to an Advance, the date
       determined pursuant to Clause 8.2;

       "Interest Period" means a period by reference to which interest is
       calculated and payable on an Advance or an overdue sum, and includes a
       Default Interest Period;

       "Internal Revenue Code" means the Internal Revenue Code of 1986, as
       amended to the date hereof and from time to time hereafter;

       "Lender" and "Lenders" means the persons identified as "Lenders" and
       listed on the signature pages of this Agreement, or, as the case may be,
       an assignee or Transferee therefrom to whom rights and/or obligations are
       assigned or transferred in accordance with Clause 25.2 or 25.3, and
       includes a successor of any such person;

       "Lending Office" means in relation to a Lender, the office or offices
       through which it is acting for


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       the purpose of this Agreement, which office or offices initially are set
       out in Schedule 1;

       "LIBOR" means, in relation to any Advance or any overdue sum:-

       (a)    the rate determined by the Agent to be the arithmetic mean
              (rounded upwards, if necessary, to the nearest five decimal
              places) of the offered quotations for deposits in the relevant
              Available Currency for a period equal to the Interest Period
              relating to that Advance (or overdue sum) which appear on the
              Telerate Display Screen page number 3750 (or such other page(s) as
              may replace such pages from time to time on that system) at or
              about 11.00 a.m. (London time) on the relevant Rate Fixing Day; or

       (b)    if no such offered quotations appear on the relevant page as
              aforesaid the arithmetic mean (rounded upwards, if necessary, to
              the nearest five decimal places) of the respective rates, as
              supplied to the Agent at its request, quoted (subject to Clause
              8.1.3) by the Reference Lenders to prime lenders in the London
              Interbank Market at or about 11.00 a.m. (London time) on the
              relevant Rate Fixing Day for the offering of deposits in the
              relevant Available Currency and in an amount comparable to the
              amount of, and for a period equal to the Interest Period relating
              to, that Advance (or overdue sum) for delivery on the first day of
              that Interest Period;

       "LIT" means the lawful currency from time to time of Italy;

       "Loan" means the aggregate principal amount of all Advances for the time
       being outstanding under this Agreement, and "Tranche A Term Loan" and
       "Tranche B Multicurrency Revolving Loan" shall be construed accordingly;

       "Majority Lenders" means one or more Lenders, the sum of whose Relevant
       Amounts equals or exceeds 51 per cent. (51%) of the aggregate of the
       Relevant Amounts of all the Lenders;

       "Mandatory Liquid Asset Costs" means, in relation to each Lender, the
       additional cost to such Lender of complying with (i) the relative reserve
       asset ratio required by the Bank of England from time to time (if any),
       expressed as


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       a percentage per annum and calculated as set forth in Schedule 5, or (ii)
       any analogous requirement of any central banking or financial regulatory
       authority imposed at the date of this Agreement in respect of the funding
       or maintenance of commitments or loans of the type contemplated hereby
       and applicable to a specific currency;

       "Margin" means 1.00% for the period commencing on the Initial Drawdown
       Date and ending on the last day of the fourth full Accounting Quarter
       following such date, and thereafter 0.75%, upon ChiRex Inc. (on a
       consolidated basis) achieving a level of Total Debt/EBITDA Ratio equal to
       1.5 : 1 (and only for such time as such level continues to be achieved),
       tested as at the last day of the immediately preceding Accounting Quarter
       and calculated as provided in Clause 13.4 provided that:-

       (a)    there shall be no decrease in the Margin if there has occurred an
              Event of Default or a Potential Event of Default which is
              continuing and the Margin shall remain at or increase to 1.00%
              until such time as such Event of Default or Potential Event of
              Default is no longer continuing, whereupon the Margin shall be
              determined as aforesaid; and

       (b)    any reduction or increase in the Margin shall take effect as from
              the date of receipt by the Agent of the relevant accounts in
              accordance with Clause 13.3.4 (on the basis that in the case of a
              reduction or increase taking effect during an Interest Period the
              interest payable on the Interest Payment Date will reflect such
              reduction or increase on a time apportioned basis);

       "Margin Stock" means margin stock within the meaning of Regulations G, T,
       U and X of the Board of Governors of the Federal Reserve System of the
       U.S.;

       "Material Adverse Effect" has the meaning given thereto in Clause 1.2.5;

       "Material Agreement" means, at any time, any agreement or group of
       related agreements (i) to which, individually or in the aggregate, is
       attributable (on a reasonable estimation basis) 10% or more of either the
       gross turnover or the EBITDA of the ChiRex Group for the Accounting
       Reference Period then in effect, or, at any time before 31st December,
       1997, for the Accounting Reference Period ending on 31st December, 1998,
       or (ii)


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       the termination or non-performance of which would constitute a Material
       Adverse Effect;

       "Material Subsidiary" means any direct or indirect subsidiary of ChiRex
       Inc. other than a subsidiary that has been designated in writing by the
       Agent as a Non-Material Subsidiary; provided that upon each such
       designation, ChiRex Inc. shall deliver a certificate signed on behalf of
       ChiRex Inc. by two of its officers, certifying that (i) the aggregate
       gross turnover of the Non-Material Subsidiaries as at such date does not
       exceed 10% of the gross turnover of ChiRex Inc. and its subsidiaries as
       at such date, (ii) the aggregate gross assets of the Non-Material
       Subsidiaries as at such date does not exceed 10% of the gross assets of
       ChiRex Inc. and its subsidiaries as at such date, and (iii) the aggregate
       EBITDA of the Non-Material Subsidiaries as at such date does not exceed
       10% of the EBITDA of ChiRex Inc. and its subsidiaries as at such date.
       For this purpose:-

       (a)    in the case of a person which itself has subsidiaries, the
              calculation shall be made by using the consolidated gross turnover
              or gross assets or EBITDA of it and its subsidiaries; and

       (b)    the calculation of consolidated gross turnover or gross assets or
              EBITDA shall be made by reference to:-

(i)    the accounts of the relevant subsidiary (or, as the case may be, a
       consolidation of the accounts of it and its subsidiaries) used for the
       purpose of the then latest unaudited quarterly or audited annual
       consolidated accounts of ChiRex Inc. delivered to the Agent under Clause
       4.1.1 or 13.3 (as the case may be) or, in the case of a newly acquired or
       formed subsidiary, the most recent unaudited quarterly or audited annual
       accounts of the relevant subsidiary (or, as the case may be, a
       consolidation of the accounts of it and its subsidiaries), provided such
       accounts report a period ending no earlier than six months from the date
       of such calculation; and

(ii)   the unaudited quarterly or audited annual consolidated accounts (as the
       case may be) of ChiRex Inc. on a pro forma basis together with any
       newly-acquired or formed subsidiary described in sub-clause (b)(i) of
       this definition;


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       "Multiborrower Revolving Note" means the note(s) dated the date hereof to
       be issued by each member of the ChiRex Group (other than the Borrower) to
       the Borrower in respect of the proceeds of the Tranche B Facility;

       "Net Cash Proceeds" means the remainder of cash proceeds arising from the
       disposal of any fixed asset or any part of the business of any Obligor,
       or from any Equity Sale, after deducting (i) in the case of such a
       disposal, required repayment of Financial Indebtedness secured by such
       asset and/or Financial Indebtedness incurred to purchase such asset or
       business (or any refinancings thereof), (ii) reasonable costs related to
       such Equity Sale or disposal, and (iii) reasonable provision for Taxes
       attributable to such Equity Sale or disposal;

       "Net Income" means, in respect of any period and in relation to:

       (a)    the Borrower, the profit shown on the Borrower's profit and loss
              account for such period, determined in accordance with Approved
              Accounting Principles; or

       (b)    the ChiRex Group, the profit shown on the profit and loss account
              on a consolidated basis for the ChiRex Group for such period,
              determined in accordance with the applicable Approved Accounting
              Principles, provided that there shall be excluded (i) the profit
              of any person (other than any Obligor) in which any other person
              (other than any Obligor or any of their respective subsidiaries)
              has a joint interest, except to the extent of the amount of
              dividends or other distributions actually paid to any Obligor or
              any of their respective subsidiaries by such person during such
              period and (ii) the profit of any person accrued prior to the date
              it becomes a subsidiary of any Obligor or any of their respective
              subsidiaries or is merged into or consolidated with any Obligor or
              any of their respective subsidiaries or that person's assets are
              acquired by any Obligor or any of their respective subsidiaries;

       "Net Tranche B Multicurrency Revolving Commitment" means, in relation to
       any Lender, its Tranche B Multicurrency Revolving Commitment less, to the
       extent it is a WCP Provider under the Tranche B Facility, the amount of
       its WCP Commitment under the Tranche B Facility pursuant to Clause 3.6.1
       from time to time;


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       "Non-Material Subsidiary" means a subsidiary of ChiRex Inc. that is not a
       Material Subsidiary;

       "Obligor" means the Borrower, each Guarantor and any other member of the
       ChiRex Group which is or becomes a party to a Finance Document;

       "Operating Budget" means a budget for the ChiRex Group in form and scope
       reasonably satisfactory to the Agent and consistent with the financial
       reporting of the ChiRex Group (including budgeted statement of income,
       and sources and uses of cash and balance sheets);

       "Participation" means, in relation to a Lender and a Facility, its right,
       title, interest and obligations in relation to such Facility, namely:-

       (a)    its right to receive its Participation Proportion of principal and
              interest in respect of outstanding Advances under the Facility
              including its right to any consequential payment pursuant to
              Clause 3.7.1; and

       (b)    its obligation to participate in its Participation Proportion in
              future Advances up to the limit of that Facility;

       "Participation Proportion" means, in relation to a Lender and a Facility,
       the proportion in which that Lender has agreed to participate in that
       Facility pursuant to Clause 3.1 (Basis of Participation) and subject to
       Clause 3.6 (the WCP Facilities);

       "PBGC" means the Pension Benefit Guaranty Corporation (or any successor
       thereto);

       "Permitted Indebtedness" means, in relation to the Obligors:-

       (i)    Financial Indebtedness outstanding under any of the Facilities;

       (ii)   the Continuing Indebtedness (and refinancings thereof), provided
              that the principal amount thereof shall not be increased after the
              date of this Agreement;

       (iii)  finance leases, hire purchase and conditional sale agreements in
              relation to which the maximum aggregate liability on termination
              of


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              such leases or agreements would not exceed in aggregate GBP
              1,000,000 (or its equivalent);

       (iv)   guarantees, indemnities or bonds given in the ordinary course of
              trading activities;

       (v)    Financial Indebtedness arising from a loan or credit permitted by
              Clause 13.2.12;

       (vi)   Financial Indebtedness (and any refinancings thereof) of any
              person which, by way of acquisition after the date of this
              Agreement, will be consolidated on the ChiRex Group's financial
              statements, provided that: (i) such Financial Indebtedness was
              subsisting prior to the date of the person's acquisition, (ii)
              such Financial Indebtedness was not incurred in contemplation of
              or in connection with the acquisition, (iii) the principal amount
              of such Financial Indebtedness shall not have been and shall not
              be increased after the date of such acquisition above the amount
              outstanding on such date or, if greater, the maximum amount
              available to be drawn under the documentation governing such
              Financial Indebtedness as in effect on such date, and (iv) the
              aggregate amount of such Financial Indebtedness outstanding at any
              one time, when added to that outstanding and permitted pursuant to
              item (x) of this definition, shall not exceed GBP 10,000,000 (or
              its equivalent);

       (vii)  Financial Indebtedness in connection with the provision of customs
              bonds required in the ordinary course of trading of the relevant
              person;

       (viii) Permitted Subordinated Debt;

       (ix)   guarantees, indemnities or similar assurances given by an Obligor
              in respect of obligations of another member of the ChiRex Group
              which is a Tier I Guarantor, the guaranteed obligations in each
              case in this paragraph (ix) being themselves permitted under this
              Agreement;

       (x)    Financial Indebtedness not falling within any other paragraph of
              this definition in a principal amount which when added to
              Financial Indebtedness outstanding and permitted pursuant to item
              (vi) of this definition, does not exceed GBP 10,000,000 (or its
              equivalent) at any one time outstanding; and


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       (xi)   any other Financial Indebtedness incurred with the consent of the
              Agent (acting on the instructions of the Majority Lenders);

       "Permitted Investment" means, in relation to the Obligors:-

       (i)    cash;

       (ii)   commercial paper maturing not more than nine months from the date
              of issue and rated at least A-1 by Standard & Poor's Ratings Group
              or P-1 by Moody's Investors Service, Inc.;

       (iii)  any deposit of not more than one year's maturity with, or
              acceptance maturing not more than one year after issue accepted
              by, a bank or credit institution which has a combined capital and
              surplus and undistributable profits of not less than GBP
              100,000,000 (or its equivalent) and whose short term unsecured,
              unsubordinated debt rating is at least A-1 by Standard & Poor's
              Ratings Group or P-1 by Moody's Investors Service, Inc.;

       (iv)   securities issued or directly and fully guaranteed or insured by
              the governments of Great Britain or the United States of America
              or any agency or instrumentality thereof having maturities of not
              more than one year from the date of acquisition;

       (v)    repurchase obligations with a term of not more than seven days
              fully collateralised by underlying securities of the types
              described in paragraphs (ii) and (iii) above entered into with any
              bank meeting the qualifications specified in paragraph (iii)
              above;

       (vi)   debt securities having not more than one year until final maturity
              and listed on a recognised stock exchange and rated at least Aa by
              Moody's Investors Service, Inc. or AA by Standard & Poor's Ratings
              Group;

       (vii)  loans or credits permitted pursuant to Clause 13.2.12;

       (viii) investments in the ordinary course of the trading business of the
              relevant person; and


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       (ix)   investments in subsidiaries in the respective amounts in effect on
              the date of this Agreement;

       "Permitted Security Interest" means, in relation to the Obligors:-

       (i)    Security Interests granted with the consent of the Agent (acting
              on the instructions of the Majority Lenders);

       (ii)   liens arising and subsisting by operation of law and in the
              ordinary course of business activities;

       (iii)  rights of set-off existing in the ordinary course of trading
              activities between such Obligor and its suppliers or customers,
              and rights of set-off arising by operation of law by virtue of the
              provision to such person of bank clearing facilities or overdraft
              facilities permitted hereunder;

       (iv)   any retention of title to goods supplied to such Obligor where
              such retention is permitted by the relevant person in the ordinary
              course of its trading activities and on customary terms;

       (v)    Security Interests securing Financial Indebtedness referred to in
              paragraph (vi) of the definition of "Permitted Indebtedness",
              provided that: (i) such Security Interest was subsisting prior to
              the date of the person's acquisition by such Obligor, (ii) such
              Security Interest was not granted in contemplation of or in
              connection with the acquisition, and (iii) the principal Financial
              Indebtedness secured by any such Security Interest shall not be
              increased after the date of such acquisition;

       (vi)   Security Interests securing the Continuing Indebtedness on the
              date of this Agreement, provided that the principal Financial
              Indebtedness secured by any such Security Interest shall not be
              and shall not have been increased after such date;

       (vii)  Security Interests covering assets the subject of equipment and
              finance leases, hire purchase, conditional sale or similar
              arrangements entered into by such Obligor which are permitted by
              this Agreement;


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       (viii) Security Interests arising in respect of any escrow arrangements
              put into place for the purpose of a disposal or acquisition by
              such Obligor permitted by this Agreement; and

       (ix)   Security Interests of such Obligor not falling within any other
              paragraph of this definition securing Financial Indebtedness
              (including interest and fees relating thereto) which does not
              exceed GBP 100,000 (or its equivalent) at any one time;

       in each case, other than any of the aforementioned imposed pursuant to
       Section 401(1)(29) or 412(n) of the Internal Revenue Code or by ERISA;

       "Permitted Subordinated Debt" means unsecured Financial Indebtedness of
       the Obligors provided that either (i) such Financial Indebtedness is
       subordinated to the Financial Indebtedness outstanding under the Finance
       Documents upon terms in all respects reasonably satisfactory to the Agent
       taking into consideration the market in or into which it is issued, or
       (ii) the terms of subordination of such Financial Indebtedness provide,
       without limitation, that:

       (a)    such Financial Indebtedness shall not amortise prior to the final
              date of maturity, which date shall be no earlier than 31st
              December, 2003;

       (b)    no amount in respect of principal of such Financial Indebtedness
              (by way of purchase, redemption or otherwise) shall be paid until
              all amounts which may be or become payable under the Finance
              Documents have been irrevocably paid in full and all Commitments
              hereunder shall have terminated, except on terms and conditions
              reasonably satisfactory to the Majority Lenders and the Agent;

       (c)    no amount in respect of interest on such Financial Indebtedness
              may be paid until all amounts which may be or become payable under
              the Finance Documents have been irrevocably paid in full and all
              Commitments hereunder shall have terminated, except on terms and
              conditions reasonably satisfactory to the Majority Lenders and the
              Agent;

       (d)    no default in respect of such Financial Indebtedness shall arise
              and the lender thereof shall waive any available remedies as a
              result thereof until all amounts which may be or become payable
              under the


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              Finance Documents have been irrevocably paid in full and all
              Commitments hereunder shall have terminated;

       (e)    each lender in respect of such Financial Indebtedness shall agree
              that it will not accelerate any such Financial Indebtedness or
              otherwise declare it prematurely payable, enforce any such
              Financial Indebtedness (to the maximum extent permitted by law),
              petition for or otherwise take any steps with a view to any
              insolvency, liquidation, re-organization, administration or
              dissolution proceedings or any voluntary arrangement or assignment
              for the benefit of creditors or any similar proceedings, including
              without limitation any event referred to in Clause 14.1.5 to
              Clause 14.1.10 (inclusive) involving any member of the ChiRex
              Group or otherwise exercise any rights or pursue any remedy for
              the recovery of such Financial Indebtedness or in respect of any
              breach of covenant, misrepresentation or non-observance of any
              provision of such Financial Indebtedness, in each case, until all
              amounts which may be or become payable under the Finance Documents
              have been irrevocably paid in full and all Commitments hereunder
              shall have been terminated; and

       (f)    each lender in respect of such Financial Indebtedness shall agree
              to turn over to the Agent all payments and distributions received
              in respect of any proceeding referred to in Clause 14.1.5 to
              Clause 14.1.10 (inclusive) involving the Borrower, and any other
              amount paid in a manner inconsistent with clauses (a) and (b) of
              this definition, for application by the Agent to the satisfaction
              of outstandings under this Agreement until all amounts which may
              be or become payable under the Finance Documents have been
              irrevocably paid in full and all Commitments hereunder shall have
              been terminated;

       "Potential Event of Default" means any event which, with the giving of
       notice or the lapse of time or both or the making of any determination or
       the fulfilment of any condition, will constitute an Event of Default,
       provided that such notice, lapse of time, determination or condition is
       in any case specified or referred to in the relevant Event of Default as
       set forth in Clause 14.1;

       "Qualifying Lender" means an institution which is (i) a bank resident in
       the U.K. for the purpose of Section 349 of the Income and Corporation
       Taxes Act 1988 (as in effect on the date of this Agreement) and is
       beneficially


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       entitled to its Participation Proportion of interest due on the Advances
       or (ii) a bank lending through any other branch, affiliate or agency if
       the bank or affiliate (as the case may be) is resident in a country with
       which the United Kingdom has an appropriate double taxation treaty
       pursuant to which that bank or affiliate (as the case may be) is entitled
       to receive principal, interest and fees under this Agreement from the
       Borrower without withholding of United Kingdom income Tax or is otherwise
       entitled to receive principal, interest and fees without such
       withholding;

       "Rate Fixing Day" means, in relation to an Advance, the Business Day
       being two Business Days prior to the Drawdown Date for that Advance and,
       in relation to any Interest Period, the Business Day being two Business
       Days prior to the first day of that Interest Period provided that, in
       relation to an Advance denominated in GBP the Rate Fixing Day shall be
       the Drawdown Date or, as the case may be, the first day of the relevant
       Interest Period;

       "Recovering Lender" has the meaning given to it in Clause 19.1;

       "Recovery" has the meaning given to it in Clause 19.1;

       "Reference Lenders" means, subject to Clause 25.5.2, Bankers Trust
       Company and Midland Bank plc;

       "Relevant Amounts" means, in relation to a Lender, the aggregate from
       time to time of (a)(i) before the making of the initial Advances, its
       Commitments or (ii) after the making of the initial Advances, all
       Advances made by it then outstanding, or (b) if the Commitments have been
       terminated, all Advances made by it then outstanding;

       "Repayment Dates" means the semi-annual dates commencing on 31st
       December, 1998, as detailed in Schedule 2;

       "Repayment Schedule" means the repayment schedule for the Tranche A Term
       Facility which is set out in Schedule 2;

       "Reservations" means limitations on enforceability of legal documents
       dictated by local law and used as qualifications in legal opinions
       delivered to and accepted by the Agent in connection with the Initial
       Drawdown or the accession of a Guarantor pursuant to a Deed of Accession;


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       "Restricted Payment" means any of (i) the redemption, purchase,
       retirement or acquisition by ChiRex Inc. of any shares, warrants or other
       equity related securities issued by it, or the setting apart by it of any
       sum for such purpose, or other reduction by it of its capital, (ii) the
       declaration or payment by ChiRex Inc. or making of any other distribution
       on any ordinary or other shares issued by it, and (iii) before the
       Achievement Date only, the incurrence of any Capital Expenditure by the
       ChiRex Group in excess of that set forth for the relevant Accounting
       Reference Period in the Business Plan;

       "Revolving Lenders" means any Lender participating in the Tranche B
       Multicurrency Revolving Facility;

       "Sale and Purchase Agreement" means the Agreement in the agreed terms
       dated 23rd September 1997 between Glaxo Group Limited and ChiRex (Annan)
       Limited for the Sale and Purchase of the Business and Assets of Glaxo
       Group Limited operated from its site at Annan, Dumfries, Scotland;

       "Same Day Funds" means funds settled for value on the same day throughout
       a clearing system relevant for the currency concerned and such other
       funds as the Agent shall specify as being customary at the time for such
       settlement;

       "Scheme" means the ChiRex Pension Plan as established by an interim trust
       deed dated 5th February, 1996;

       "SEC" means the United States Securities and Exchange Commission (or any
       successor thereto);

       "Security Agent" means Bankers Trust Company as agent for the Finance
       Parties under the Security Documents or any other person as may from time
       to time hold the whole or any part of the security created thereby
       pursuant to Clause 16;

       "Security Documents" means each of:-

       (a)    Pledge Agreement dated as of the date hereof between the Security
              Agent, on behalf of the Lenders, and ChiRex Inc. relating to all
              the issued and outstanding shares of capital stock of ChiRex
              America Inc. and the Borrower, and the Holdings Note;


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       (b)    Debenture dated as of the date hereof between the Security Agent,
              on behalf of the Lenders, and the Borrower relating to all the
              issued and outstanding shares of ChiRex (Dudley) Limited and
              ChiRex (Annan) Limited, the Annan Note and the Multiborrower
              Revolving Notes;

       (c)    Debenture dated the date hereof by ChiRex (Dudley) Limited in
              favour of the Security Agent, on behalf of the Lenders, relating
              to the Dudley Facility and certain other assets of ChiRex (Dudley)
              Limited;

       (d)    Debenture dated the date hereof by ChiRex (Annan) Limited in
              favour of the Security Agent, on behalf of the Lenders, relating
              to certain assets of ChiRex (Annan) Limited; and

       (e)    Standard Security in agreed terms dated the date hereof by ChiRex
              (Annan) Limited in favour of the Security Agent, on behalf of the
              Lenders, relating to the Annan Facility;

       in each case as the same may be amended, from time to time, in accordance
       with its terms;

       "Security Interest" means any mortgage, charge (fixed or floating),
       standard security, pledge, lien, right of set-off hypothecation, trust,
       assignment by way of security, reservation of title, or any other
       security interest whatsoever, howsoever created or arising or any other
       agreement or arrangement (including, without limitation, a sale and
       repurchase arrangement) having the practical effect of conferring
       security, and any agreement to enter into, create or establish any of the
       foregoing;

       "Standard Security" means a standard security in terms of the
       Conveyancing and Feudal Reform (Scotland) Act 1970;

       "Syndication" has the meaning set forth in Clause 3.5;

       "Taxes" means and includes all present and future income and other taxes,
       levies, assessments, imposts, deductions, charges, duties, compulsory
       loans and withholdings whatsoever and wheresoever imposed and any charges
       in the nature of taxation together with interest thereon and penalties
       and fines with respect thereto, if any, and any payments made on or in
       respect thereof; and "Tax" and "Taxation" shall be construed accordingly;


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       "Tier I Guarantor" means any Guarantor which (i) has guaranteed all
       obligations of each Obligor hereunder and the amount of which guarantee
       is not subject to any limitation hereunder or under any Deed of
       Accession, if applicable, and (ii) for the purpose of securing such
       guarantee, has entered into one or more Security Documents in favour of
       the Security Agent creating in favour of the Security Agent a valid,
       perfected, first priority Security Interest in all or substantially all
       of such Guarantor's assets;

       "Total Borrowings" means, at any time, the aggregate outstanding amount
       of all Financial Indebtedness of all Obligors, calculated on a
       consolidated basis;

       "Total Commitments" means, together, the Lenders' Commitments.

       "Total Debt" means, as at any date of determination, in respect of any
       person or persons, the aggregate principal amount of Financial
       Indebtedness of such person or, on a consolidated basis, persons (as
       applicable), determined in accordance with the applicable Approved
       Accounting Principles;

       "Total Debt/EBITDA Ratio" means, at any time, the ratio of (i) Total Debt
       as of the last day of the immediately preceding Accounting Quarter, to
       (ii) consolidated EBITDA for the immediately preceding four Accounting
       Quarters, in each case in respect of ChiRex Inc.;

       "Total Debt Service" means, in respect of any period and any person or
       persons, the aggregate of (a) Total Interest and (b) the aggregate
       principal amount of Financial Indebtedness of such person or, on a
       consolidated basis, persons (as applicable) scheduled to be repaid
       (having regard to any reductions in respect thereof due to previous
       prepayment of any such amount where such prepayment occurred in a
       previous period) during such period under the terms and conditions
       relating to such Financial Indebtedness;

       "Total Interest" means, in respect of the relevant testing period, the
       aggregate of all interest (including amounts in the nature of interest in
       connection with any interest rate and/or currency swap, cap, floor,
       collar or other similar arrangement), guarantee fees, commitment fees and
       other costs and fees of a similar nature (not including, to the extent
       otherwise included, costs of issuance of debt, equity or warrants or
       amortisation of


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       debt discount) due in respect of Total Borrowings (including, for
       purposes of calculating "Total Borrowings" and notwithstanding sub-clause
       (xiii) of the definition of "Financial Indebtedness", 100% of the face or
       notional amount of each interest rate or currency swap, collar or other
       similar agreement or other hedging or derivative instrument as the
       Financial Indebtedness attributable thereto) and payable by the ChiRex
       Group during such period (including interest, the interest finance charge
       element of hire-purchase, credit sale and conditional sale agreements and
       of lease rentals under finance leases), less the sum of all interest
       (including amounts in the nature of interest in connection with any
       interest rate and/or currency swap, cap, floor, collar or other similar
       arrangement), guarantee fees, commitment fees and other costs and fees of
       a similar nature payable to the ChiRex Group during such period;

       "Tranche A Facility" or "Tranche A Term Facility" means the Tranche A
       Term loan facility not in excess of the Tranche A Term Commitments
       granted to the Borrower hereunder (as the same may be cancelled, reduced,
       varied or terminated in accordance with the terms of this Agreement);

       "Tranche A Term Commitment" means, in relation to the participation of
       any Lender in the Tranche A Term Facility, the amount stated opposite its
       name in Schedule 1 in relation to that Facility (or in the case of a
       Transferee, the amount stated in the Schedule to the relevant Transfer
       Certificate as being transferred to that Transferee), in each case as the
       same may be transferred (in whole or in part), cancelled, reduced, varied
       or terminated in accordance with the terms of this Agreement;

       "Tranche B Facility" or "Tranche B Multicurrency Revolving Facility"
       means the Tranche B multicurrency revolving loan facility not in excess
       of the Tranche B Multicurrency Revolving Commitments granted to the
       Borrower hereunder (as the same may be cancelled, reduced, varied or
       terminated in accordance with the terms of this Agreement);

       "Tranche B Multicurrency Revolving Commitment" means, in relation to the
       participation of any Lender in the Tranche B Multicurrency Revolving
       Facility, the amount (or the Equivalent Amount thereof) stated opposite
       its name in Schedule 1 in relation to the Facility (or in the case of a
       Transferee, the amount or Equivalent Amount of such amount stated in the
       Schedule to the relevant


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       Transfer Certificate as being transferred to that Transferee), in each
       case as the same may be transferred (in whole or in part), cancelled,
       reduced, varied or terminated in accordance with the terms of this
       Agreement;

       "Transfer" has the meaning given to it in Clause 25.2;

       "Transfer Certificate" means a certificate substantially in the form set
       out in Schedule 7;

       "Transferee" means a bank, financial institution or other person to which
       a Lender seeks to transfer or has transferred all or part of its rights
       and obligations hereunder;

       "United Kingdom" or "UK" means the United Kingdom of Great Britain and
       Northern Ireland;

       "United States" or "US" means the United States of America;

       "USD" means the lawful currency from time to time of the United States;

       "US Obligor" means any Obligor organised under the laws of any
       jurisdiction within the the United States;

       "VAT" means value added tax imposed in any relevant jurisdiction or any
       other tax of a substantially similar nature substituted therefor from
       time to time;

       "WCP Advance" means an Advance under a WCP Facility;

       "WCP Agreement" means an agreement between a WCP Provider and the
       Borrower relating to a WCP Facility;

       "WCP Commitment" means, in respect of any WCP Provider for a WCP
       Facility, the amount designated by the WCP Provider pursuant to Clause
       3.6.1, as such WCP Commitment may be reduced pursuant to the terms of
       this Agreement;

       "WCP Facility" means a revolving credit facility made available by a WCP
       Provider to the Borrower pursuant to Clause 3.6 and "WCP Facilities"
       means all such facilities;

       "WCP Provider" means any Lender acting through a branch or affiliate in
       respect of a WCP Commitment of that Lender;


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       "Working Capital" means in relation to a person or group of persons under
       any Approved Accounting Principles, trade and other debtors in respect of
       operating items plus prepayments and inventory less trade and other
       creditors in respect of operating items and less accrued expenses and
       accrued costs, in each case determined in accordance with such Approved
       Accounting Principles for such person or, on a consolidated basis, for
       such persons (as the case may be); and

       "Yen" means the lawful currency from time to time of Japan.

1.2    Construction of Other Terms

       In this Agreement, unless the context otherwise requires, a reference
       to:-

1.2.1  "affiliate" means in relation to any person (a) any person (other than a
       subsidiary) which, directly or indirectly, is in control of, is
       controlled by, or is under common control with such person, or (b) any
       person who is a director or officer (i) of such person, (ii) of any
       subsidiary of such person or (iii) of any person described in clause (a)
       above. For purposes of this definition, "control" of a person shall mean
       the power, direct or indirect, (i) to vote 25% or more of the securities
       having ordinary voting power for the election of directors of such
       person, whether by way of ownership of securities, contract, proxy or
       otherwise, or (ii) to direct or cause the direction of the management and
       policies of such person, whether by ownership of securities, contract,
       proxy or otherwise;

1.2.2  "assets" means business, undertaking, property, assets (tangible or
       intangible), revenues, rights and uncalled capital, wherever situated,
       present, future and contingent (including uncalled share capital), and
       every kind of interest in an asset, except that the word "contingent"
       shall not be deemed included in this definition where the definition is
       used in provisions relating to financial accounting;

1.2.3  "indebtedness" includes any obligation (whether incurred as principal or
       as surety) for the payment or repayment of money, whether present or
       future, actual or contingent, except that the word "contingent" shall not
       be deemed included in this definition where the definition is used in
       provisions relating to financial accounting;


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1.2.4  a document or other writing being "in the agreed terms" means that the
       relevant document or writing is in form and substance satisfactory to the
       Agent and has been initialled by or on behalf of the Agent and the
       Borrower (or their respective agents) on or before the date hereof;

1.2.5  an event or matter having a "Material Adverse Effect" is to be construed
       as a reference to an event or matter (a) which has or is reasonably
       likely to have a material adverse effect on the prospects, financial
       condition, business, assets or revenues of the ChiRex Group taken as a
       whole such that the Obligors, taken as a whole, will be, or are
       reasonably likely to be, unable to perform in a timely and diligent
       manner all or any of their material obligations (including, without
       limitation, payment obligations) under each of the Finance Documents or
       (b) resulting in any material term of the Finance Documents not being
       legal, valid and binding on and enforceable against any Obligor party
       thereto, subject only to the Reservations;

1.2.6  a "month" means (save where used in the expression "calendar month") a
       period starting on one day in a calendar month and ending on the
       numerically corresponding day in the next calendar month (or in a
       subsequent calendar month in the case of the plural "months"), provided
       that if:-

       (a)    any such period would otherwise end on a day which is not a
              Business Day, it shall end on the next Business Day in the same
              calendar month, or if none, on the preceding Business Day; and

       (b)    a period starts on the last Business Day in a calendar month or if
              there is no numerically corresponding day in the month in which
              that period ends, that period shall end on the last Business Day
              in that later month;

       (and references to "months" shall be construed accordingly);

1.2.7  "outstanding" under a Facility means the principal amount of all Advances
       outstanding under such Facility;

1.2.8  a "person" includes any person, firm, company, corporation, government,
       state or agency of a state or any undertaking (within the meaning of
       Section 259(1) of the Companies Act 1985) or other entity or association


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       (whether or not having separate legal personality), or any two or more of
       the foregoing;

1.2.9  "repayment" includes "prepayment" and its grammatical variations and
       cognate expressions shall be construed accordingly;

1.2.10 "subsidiary" means, with respect to any person, any corporation or other
       person more than fifty percent (50%) of whose securities or other
       ownership interests having ordinary voting power for the election of
       directors or similar representatives (other than securities having such
       power only by reason of the happening of a contingency) are, as of the
       date of determination thereof, directly or indirectly owned by such
       person or one or more of such person's subsidiaries; and

1.2.11 "winding-up" of any person includes its dissolution and/or termination
       and/or any equivalent or analogous proceedings under the law of any
       jurisdiction in which the person concerned is incorporated, registered,
       established or carries on business or to which that person is subject.

1.3    Other Provisions

       Except where a contrary intention appears, in this Agreement:-

1.3.1  a reference to an Obligor or a Finance Party is, where relevant, deemed
       to be a reference to or to include, as appropriate, their respective
       successors or assigns;

1.3.2  references to Clauses and Schedules are references to, respectively,
       clauses of and schedules to this Agreement;

1.3.3  a reference to any agreement, deed or other instrument (including the
       Finance Documents) is to be construed as a reference to that agreement,
       deed or other instrument as it may have been or hereafter be, from time
       to time, amended, varied, supplemented, restated or novated but excluding
       for this purpose any amendment, variation, supplement or modification
       which is contrary to any provision of any of the Finance Documents;

1.3.4  a reference to a statute, law, rule, regulation or statutory instrument
       is to be construed as a reference to that statute as the same may have
       been, or may from time to time hereafter be, amended or re-enacted;

1.3.5  a time of day is a reference to London, England time;


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1.3.6  the index to and the headings in this Agreement are inserted for
       convenience only and are to be ignored in construing this Agreement;

1.3.7  references to the singular shall include the plural and vice versa, and
       reference by way of masculine pronoun or adjective shall include
       references by way of the feminine, and vice versa ; and

1.3.8  accounting terms are to be construed in accordance with the Approved
       Accounting Principles.

2.     THE FACILITIES

2.1    The Facilities

2.1.1  The Lenders grant to the Borrower, upon the terms and subject to the
       conditions of this Agreement, the Facilities.

2.2    Purpose

2.2.1  Tranche A Term Facility: The proceeds of the Advance under the Tranche A
       Term Facility shall be used by the Borrower to advance to ChiRex (Annan)
       Limited the consideration for the purchase of the Assets from Glaxo Group
       Limited pursuant to the Sale and Purchase Agreement.

2.2.2  Tranche B Multicurrency Revolving Facility: The proceeds of any Advance
       under the Tranche B Multicurrency Revolving Facility (including WCP
       Advances, except as otherwise restricted by Clause 3.6) shall be used by
       the Borrower (a) up to the principal amount of GBP 1,000,000, for the
       purpose for which proceeds under the Tranche A Facility may be used and
       (b) otherwise, to advance to any member of the ChiRex Group for general
       corporate purposes of such member of the ChiRex Group.

2.2.3  Financial Assistance: No amount drawn down hereunder shall be applied by
       an Obligor in a manner which may be prohibited by any financial
       assistance or other similar laws in any relevant jurisdiction.

3.     PARTICIPATION OF LENDERS

3.1    Basis of Participation


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       Subject to the provisions of this Agreement, each Lender will participate
       in each Advance in the proportion which (i) in the case of an Advance
       under the Tranche A Term Facility, its Commitment in relation to such
       Facility as at the Drawdown Date bears to the undrawn portion of the
       Total Commitments of the Lenders in relation to such Facility as at such
       date, and (ii) in the case of an Advance under the Tranche B
       Multicurrency Revolving Facility, its Net Tranche B Multicurrency
       Revolving Commitment in relation to such Facility as at the Drawdown Date
       bears to the undrawn portion of the Total Commitments of the Lenders in
       relation to such Facility as at such date.

       None of the Lenders is obliged to participate in an Advance to the extent
       that to do so would result in the amount outstanding to it under the
       relevant Facility exceeding its Commitment in respect of that Facility.

3.2    Lending Office

3.2.1  Each Lender will participate in each Advance as aforesaid through its
       Lending Office.

3.2.2  If any Lender changes any Lending Office, that Lender agrees to notify
       the Agent and the Borrower promptly of such change and, until it does so,
       the Agent and the Borrower shall be entitled to assume that no such
       change has taken place.

3.3    Rights and Obligations of Finance Parties

3.3.1  The rights and obligations of each of the Finance Parties under the
       Finance Documents are several. Failure of any Finance Party to observe
       and perform its obligations under any Finance Document shall neither:-

       (a)    result in any other Finance Party incurring any liability
              whatsoever; nor

       (b)    relieve the Borrower or any other Finance Party from their
              respective obligations under the Finance Documents.

3.3.2  Notwithstanding any other provision of any Finance Document, the
       interests of each Finance Party are several and the total amounts
       outstanding at any time under the Finance Documents and due to each
       Finance Party constitute separate and independent debts.

3.4    Enforcement of Rights


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       Each Finance Party has the right to protect and enforce its rights
       arising out of the Finance Documents and it will not be necessary for any
       other Finance Party to be joined as an additional party in any
       proceedings brought for the purpose of protecting or enforcing such
       rights.

3.5    Syndication

       The Borrower acknowledges that, without limitation of the provisions of
       Clause 25, the Lenders may assign or transfer their respective rights
       under this Agreement ("Syndication") and the Borrower undertakes to
       assist and co-operate with the Joint Arrangers in Syndication in such
       manner and to such extent as the Joint Arrangers may from time to time
       each reasonably request including, without limitation, by:-

       (a)    providing and causing the Borrower's advisers to provide the Joint
              Arrangers with all reasonable information deemed necessary by the
              Joint Arrangers to complete Syndication, including but not limited
              to information and evaluations prepared by the Borrower and its
              advisers;

       (b)    assisting in the preparation of an Information Memorandum;

       (c)    making available officers of the Borrower and ChiRex Inc. from
              time to time and, as may reasonably be requested, causing such
              officers to attend and make presentations regarding the business
              and prospects of the Borrower and ChiRex Inc., as appropriate, at
              a meeting or meetings of Lenders or prospective Lenders;

       (d)    arranging and conducting appropriate Borrower site visits for the
              Joint Arrangers;

       (e)    selecting Interest Periods having a duration of not more than one
              month in respect of all Advances made for the first six months
              following the date of this Agreement or, if earlier, the date on
              which the Agent notifies the Borrower that in the Agent's
              determination Syndication is completed, which the Agent hereby
              agrees to do promptly upon completion of Syndication; and

       (f)    refraining and causing its subsidiaries to refrain, from placing
              any of their respective borrowings in the English, French, Spanish
              or international 


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              financial or capital markets until the earlier of (i) six months
              after the date of this Agreement, and (ii) completion of such
              Syndication as notified to the Borrower by the Agent.

3.6    The WCP Facilities

3.6.1  (a)    If a WCP Provider so agrees, at the request of the Borrower, a WCP
              Provider may designate by notice to the Agent all or part of its
              Tranche B Multicurrency Revolving Commitment as being utilised by
              its provision of a WCP Commitment in the amount designated in
              respect of a WCP Facility for the Borrower up to a maximum
              aggregate amount of GBP 2,000,000 or the Equivalent Amount
              thereof.

       (b)    Under no circumstance shall the aggregate of any WCP Provider's
              WCP Commitments exceed such WCP Provider's Tranche B Multicurrency
              Revolving Commitment.

       (c)    Subject to the terms of this Agreement,

(i)    while and to the extent a WCP Facility is made available for drawing by
       the Borrower, the Tranche B Multicurrency Revolving Commitment of the WCP
       Provider for that WCP Facility shall be reduced by the amount of its WCP
       Commitment in respect of that WCP Facility, as set forth in the
       definition of Net Tranche B Multicurrency Revolving Commitment; and

(ii)   the Borrower may cancel any undrawn element of a WCP Facility at any
       time, and in any such event or upon the expiration of the WCP Commitment
       for that WCP Facility, the Net Tranche B Multicurrency Revolving
       Commitment of the WCP Provider for that WCP Facility shall automatically
       be increased by the amount so cancelled or expired; provided that such
       WCP Provider's Net Tranche B Multicurrency Revolving Commitment shall not
       be increased in excess of its Tranche B Multicurrency Revolving
       Commitment.

3.6.2  Each WCP Facility shall be made available to the Borrower upon the terms
       of this Agreement, as follows:-

       (a)    WCP Advances may be in the form of cash Advances, letters of
              credit or revolving credit guarantees as agreed between the
              relevant WCP Provider in the applicable WCP Agreement.


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       (b)    WCP Advances under a WCP Facility shall, except as otherwise
              provided, be made available to the Borrower on the same terms and
              conditions (including without limitation the terms and conditions
              relating to interest, payments, change in circumstances, defaults,
              etc.) under which Advances under the Tranche B Multicurrency
              Revolving Facility are made available to the Borrower under this
              Agreement, provided that for purposes of Clauses 2, 3 and 5 to 11
              (inclusive):

(i)    the Lending Office(s) of a WCP Provider for purposes of its WCP Facility
       may be different from the Lending Office(s) it designates for other
       purposes under this Agreement;

(ii)   except as set forth in Clause 3.6.1, all notices to be given by or to the
       Agent in respect of a Tranche B Multicurrency Revolving Advance shall, in
       respect of a WCP Advance, be given by or to (as applicable) the WCP
       Provider for the relevant WCP Facility (and references to the Agent and
       its address in the relevant provisions of such clauses shall be deemed
       references to the relevant WCP Provider and its address for this
       purpose);

(iii)  all determinations to be made by the Agent in respect of a Tranche B
       Multicurrency Revolving Advance shall, in respect of a WCP Advance, be
       made by the relevant WCP Provider (and references to the Agent in the
       relevant provisions of such clauses shall be deemed references to the
       relevant WCP Provider for this purpose);

(iv)   all payments which, in respect of a Tranche B Multicurrency Revolving
       Advance are required to be made to the Agent hereunder shall, in respect
       of a WCP Advance to the Borrower, be made to the WCP Provider in respect
       of those WCP Advances (and references to the Agent and its address in the
       relevant provisions of such clauses shall be deemed references to the
       relevant WCP Provider and its address for this purpose); and

(v)    each WCP Advance shall be in such minimum amount and integral multiples
       as is agreed between the relevant WCP Provider and the Borrower in the
       applicable WCP Agreement.

       (c)    The foregoing notwithstanding, the Borrower and WCP Provider in
              relation to a WCP Facility may agree in a WCP Agreement between
              them to vary the interest rate applicable to WCP Advances under
              the WCP Facility, the number of WCP Advances that may be


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              outstanding at any one time, or the form of or requirement for any
              Drawdown Request or the notice required to make a drawing of a WCP
              Advance under that WCP Facility, and payment and amount of fees;
              provided that such WCP Agreement may not amend, supplement or vary
              this Agreement in any other respect without the consent of the
              Agent acting at the direction of the Majority Lenders, or, to the
              extent required by the other provisions of this Agreement, the
              Lenders.

       (d)    In addition to the foregoing, Clause 8.3.4 shall not apply in
              respect of any WCP Advance.

3.7    Certain Adjustments Relating to WCP Facilities

3.7.1  Following the occurrence and during the continuance of an Event of
       Default:-

       (a)    each WCP Provider shall promptly notify the Agent of any Recovery
              made by it from the Borrower and/or any loss or expense suffered
              by it in connection with the failure to repay in full, in each
              case by reference to the WCP Facility or WCP Facilities to which
              it is a party; and

       (b)    in the event of a shortfall as regards any or all of the Obligors
              under the Finance Documents, the Agent shall calculate the
              necessary adjustments between that WCP Provider and the other
              Lenders so that, as closely as is practicable, each Lender shares
              any loss suffered by all the Lenders (including the WCP Provider)
              in the proportion which that Lender's Commitments under the
              Facilities bears to the Total Commitments under the Facilities.

       (c)    The Lenders (including each WCP Provider) agree to accept as
              conclusive (in the absence of manifest error) the calculations of
              the Agent under paragraph (b) above and to make such consequential
              payments as between themselves as may be necessary to achieve the
              proportionate loss sharing contemplated by that paragraph (b) and
              to give effect to Clause 19.

3.7.2  Any consequential payment made by a Lender under Clause 3.7.1 above is
       without prejudice to the obligations under this Agreement of the Borrower
       to pay all amounts due and payable under this Agreement.

4.     CONDITIONS PRECEDENT


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4.1    Initial conditions precedent

4.1.1  The obligations of the Lenders to make any Advance available to the
       Borrower under this Agreement are conditioned upon the Agent and its
       legal advisers having received the following documents and evidence in
       all respects (except where otherwise specified) in form and substance
       satisfactory to the Agent and its legal advisers by 12:00 noon on the
       first Business Day prior to the Initial Drawdown Date:-

       (a)    a copy, certified as of the Initial Drawdown Date as true and
              complete by a duly authorised representative of the relevant
              Obligor, of:

(i)    the constitutional documents of each Obligor, including evidence of due
       incorporation, together with satisfactory search results of any public
       corporate registers of that Obligor;

(ii)   board (or other appropriate governing body) resolutions of each Obligor
       (A) approving the transactions and the matters contemplated by each of
       the Finance Documents, and (B) authorising or granting a power of
       attorney to a specified person or persons to (x) execute on its behalf
       each of the Finance Documents to which it is a party, and (y) give all
       notices, requests, instructions, certificates and other documents for
       that Obligor in connection with each of the Finance Documents to which it
       is a party;

(iii)  all other corporate, trust or other applicable authorisations and actions
       of it required (including without limitation any resolutions of
       shareholders or approvals of beneficiaries) to enable it to enter into,
       execute and perform those of the Finance Documents to which it is, or is
       to be, a party;

(iv)   specimen signatures of the signatories authorised by each Obligor in the
       board (or other appropriate governing body) resolutions described in
       Clause 4.1.1(a)(ii) to sign Financing Documents to which it is or is to
       be a party; and

(v)    all other resolutions, powers, declarations, approvals, consents and
       licenses (corporate, official or otherwise) necessary or appropriate for
       the entry into and performance by each Obligor of the Finance Documents
       to which it is or is to be a party, and for the enforceability and
       validity thereof;


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       (b)    duly and unconditionally executed counterparts (except where such
              documents are expressly governed (in whole or in part) by Scottish
              law, in which case such documents shall not be executed in
              counterparts) of:-

(i)    this Agreement; and

(ii)   each of the Security Documents.

       (c)    legal opinions properly addressed to the Agent and Lenders from:-

              (i)    Cravath, Swaine & Moore, U.S. legal advisers to the ChiRex
                     Group;

              (ii)   Dibb Lupton Alsop, English legal advisers to the ChiRex
                     Group; and

              (iii)  O'Melveny & Myers LLP, legal advisers to the Agent;

       (d)    (i) in relation to the Annan Facility, evidence that:

                     (A) the consummation of the transactions contemplated in
                     the Sale and Purchase Agreement and entry into the Supply
                     Agreement will occur on terms and conditions acceptable to
                     the Agent substantially contemporaneously with the Initial
                     Drawdown; and

                     (B) an executed and completed letter of obligation from
                     Brodies WS, "Disposition" in favour of ChiRex (Annan)
                     Limited, a wire transfer in respect of (i) stamp duty on
                     the Disposition in the amount of GBP 240,000 and (ii)
                     registration dues on the Disposition and Standard Security
                     in the amount of GBP 7,522, and the prior writs and land
                     registration forms 1 and 4 in respect of the Disposition,
                     have each been delivered to Tods Murray, Scottish counsel
                     for the Agent; and

              (ii) in relation to the Dudley Facility, evidence that the
              Security Interest held by Midland Bank plc has been paid and
              discharged in full substantially contemporaneously with the
              Initial Drawdown.


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       (e)    delivery of share certificates and share transfer forms and/or
              evidence of the relevant recording on the share registers with
              respect to the shares of ChiRex America Inc., the Borrower, ChiRex
              (Dudley) Limited and ChiRex (Annan) Limited, and the Holdings
              Note, the Annan Note and the Multiborrower Revolving Note, all as
              pledged pursuant to the Security Documents, and/or any other
              evidence that the Security Interests created thereby are
              appropriately perfected or will be perfected upon registration
              under applicable law;

       (f)    Environmental Report;

       (g)    Due Diligence Report (Legal);

       (h)    Business Plan;

       (i)    Operating Budget;

       (j)    Accountants' Report and Industry Report;

       (k)    in each case, unless the relevant report itself is addressed to
              the Agent and each of the Lenders, reliance letters addressed to
              the Agent and each of the Lenders in form and substance
              satisfactory to the Agent with respect to each of (i) the
              Environmental Report, to the extent it relates to the Annan
              Facility, (ii) the Due Diligence Report (Legal) as described in
              item (ii), (iii) and (iv) of the definition thereof, (iii) the
              Accountants' Report, and (iv) the Industry Report;

       (l)    analyses and evidence of insurance complying with Clause 13.2.6
              (Insurances) in scope, form and substance reasonably satisfactory
              to the Agent;

       (m)    audited consolidated financial statements for ChiRex Inc. for the
              Accounting Reference Period ended 31st December, 1996 and
              unaudited interim financial statement for the Accounting Quarter
              ended 30th June, 1997;

       (n)    each of the financial statements and other materials required
              pursuant to Clause 13.3.4 (Financial Statements and Operating
              Budget);

       (o)    copies of each of the agreements, deeds or other instruments, in
              each case containing covenants, events of default and matters
              relating to requirements for repayment in advance of scheduled


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              maturity in form and substance reasonably satisfactory to the
              Agent, evidencing the Continuing Indebtedness, certified as of the
              Initial Drawdown Date by a duly authorised representative of the
              Borrower;

       (p)    evidence that the agents for service of process named in Clause
              30.2 have accepted their respective appointments for the purposes
              of this Agreement and the other Finance Documents; and

       (q)    evidence of the payment of the fees specified in Clause 11.1.1(b).

4.1.2  When the Agent is satisfied that such conditions have been fulfilled, the
       Agent will give notice to that effect to the Borrower and each of the
       Lenders.

4.2    Additional Conditions Precedent for All Advances

4.2.1  The obligations of the Lenders to make any Advance to the Borrower is
       subject to the following further conditions precedent that on both the
       date of the relevant Drawdown Request and the relevant Drawdown Date,
       unless waived by the Agent acting in accordance with Clause 26:-

       (a)    no Event of Default or Potential Event of Default has occurred and
              continues unremedied or will occur as a result of the making of
              the Advance; and

       (b)    the representations and warranties required to be made in
              accordance with Clause 12 are true and accurate in all material
              respects in each case by reference to the facts and circumstances
              then subsisting and will remain true and accurate immediately
              after the Advance is made.

4.2.2  Each Drawdown must fall on a Business Day on or before the expiry of the
       Availability Period for the relevant Facility. Any amounts not drawn on
       or before the expiry of the Availability Period for the Facility shall be
       cancelled.

5.     DRAWDOWN PROCEDURES AND LENDERS' PARTICIPATIONS;

5.1    Drawdown of Advances

5.1.1  Whenever the Borrower wishes to borrow an Advance, the Borrower must
       deliver to the Agent a duly completed Drawdown Request not later than
       10.00 a.m. three Business 


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       Days prior to the proposed Drawdown Date (including with respect to the
       Initial Drawdown Date).

5.1.2  A Drawdown Request for an Advance delivered to the Agent must be in the
       form set out in Schedule 3 and must specify each of the following:-

       (a)    the proposed Drawdown Date for the Advance (which must be a
              Business Day falling within the Availability Period);

       (b)    the amount of the Advance which amount must be a minimum of GBP
              1,000,000 or the Equivalent Amount thereof and an integral
              multiple of GBP 500,000 or the Equivalent Amount thereof, except
              to the extent of variations from such amounts for rounding
              purposes approved by the Agent;

       (c)    the duration of the first Interest Period applicable to the
              Advance, which must comply with Clause 8.3;

       (d)    the account to which the proceeds of the Advance are to be paid;
              and

       (e)    the purpose for which the Advance is requested.

5.1.3  In no event may the amount specified in a Drawdown Request be such that
       the Loan would thereby exceed the then Total Commitments. If, however,
       the amount specified in a Drawdown Request exceeds the then Total
       Commitments, and the amount of that excess may reasonably be attributed
       to exchange rate fluctuations on or after the date a Drawdown Request is
       given, the Agent in its sole discretion may agree with the Borrower to
       adjustments, complying with the terms and conditions of this Agreement,
       in the amount of any Loan requested pursuant to such Drawdown Request so
       that the amounts requested pursuant to such Drawdown Request comply with
       this Clause 5.1.3. The Agent shall notify the Lenders promptly after any
       such adjustment is made, and all expenses, losses, damages and liability
       of the Lenders arising out of any such adjustments shall be for the
       account of the Borrower pursuant to Clause 27.1 (General Indemnity and
       Breakage Costs).

5.1.4  A Drawdown Request in relation to an Advance, once given, may not be
       withdrawn or revoked.

5.1.5  Advances under the Tranche A Term Facility may only be requested for the
       Initial Drawdown Date.


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5.1.6  Not more than fifteen separate Tranche B Multicurrency Revolving Advances
       may be outstanding at any time.

5.1.7  (a)    The Borrower may not request the drawdown of an Advance in a
              currency other than DEM, FF, LIT, GBP, CHF, Yen or USD (unless the
              Agent has confirmed in writing to the Borrower that such other
              currency is freely available to all the Lenders and is one in
              which dealings regularly occur in the London interbank market).

       (b)    Notwithstanding Clause 5.1.7(a), if before 9.15 a.m. (London time)
              on the proposed Drawdown Date for a utilisation to be denominated
              in a currency other than DEM, FF, LIT, GBP, CHF, Yen or USD:-

(i)    the Agent receives notice from a Lender that it is impracticable for the
       Lender to fund its participation for the relevant Interest Period in such
       currency in the ordinary course of its business in the London interbank
       market; or

(ii)   the drawing of the proposed Advance in such currency could, in the
       opinion of the Agent, be reasonably likely to contravene any applicable
       law or regulation;

              then:-

              (A)    the Agent shall promptly and in any event before 10.00 a.m.
                     on that Drawdown Date notify the Borrower;

              (B)    if the Agent receives notice from the Borrower by 11.00
                     a.m. on the relevant Drawdown Date, the drawdown shall not
                     be made;

              (C)    if the Agent does not receive any notice under
                     sub-paragraph (B) above, the drawdown will be denominated
                     instead in GBP and there shall be substituted in the
                     definition of "LIBOR" in Clause 1.1 the time "1.00 p.m."
                     for the time "11.00 a.m."; and

              (D)    the Borrower shall forthwith on demand indemnify each
                     Lender against any liability which that Lender incurs as a
                     consequence of the operation of this Clause 5.1.7(b).

5.2    Lenders' Participations


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5.2.1  Subject to the provisions of this Agreement, each Lender will make
       available to the Agent its Participation Proportion of the relevant
       Advance on the relevant Drawdown Date in accordance with Clause 9.1.1
       (Payments).

5.2.2  If, prior to an Advance being made, a Lender's Commitment has been or
       will be wholly cancelled or terminated pursuant to this Agreement, such
       Lender will not participate in such Advance.

5.3    Notice to the Lenders of a Proposed Drawdown

       Whenever the Agent receives a Drawdown Request which complies with the
       requirements of Clause 5.1, the Agent will promptly give notice to each
       of the Lenders of (a) the details of the requested Advance, and (b) the
       amount of such Lender's participation (or deemed participation) in the
       relevant Advance.

6.     REPAYMENT OF ADVANCES

6.1    Repayment of Tranche A Term Loans

6.1.1  On each Repayment Date, the Borrower shall repay or cause the repayment
       (as applicable) of the aggregate amount of the Tranche A Term Loan set
       forth opposite such date in Schedule 2.

6.1.2  If any Repayment Date is not a Business Day it will be adjusted to fall
       on the next succeeding Business Day unless the result of such adjustment
       would be to carry that Repayment Date into another calendar month, in
       which event such Repayment Date shall be the last preceding Business Day.

6.1.3  Any amount of the Tranche A Term Loan repaid under this Agreement may not
       be redrawn and the relevant Tranche A Term Commitment shall be reduced by
       an amount equal to the amount of such Loan so repaid.

6.2    Repayment of Tranche B Multicurrency Revolving Advances

6.2.1  Each Advance under the Tranche B Multicurrency Revolving Facility shall
       be borrowed for a period equal to the Interest Period selected in
       relation to such Advance. The Borrower shall accordingly repay each such
       Advance on the last day of such Interest Period in the currency in which
       such Advance was made to the Borrower.


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6.2.2  The Borrower shall ensure that the aggregate principal amount of all
       Tranche B Multicurrency Revolving Advances from time to time outstanding
       does not exceed the aggregate amount of the Tranche B Multicurrency
       Revolving Facility from time to time (including Equivalent Amounts in
       respect of Advances not denominated in GBP).

6.2.3  Subject to the provisions of this Agreement, Tranche B Multicurrency
       Revolving Advances repaid in accordance with Clause 6.2.1 above shall be
       capable of being redrawn by the Borrower.

6.2.4  Subject to the terms of this Agreement: (i) on 31st December, 2000, the
       Borrower shall repay such portion of the outstanding Tranche B
       Multicurrency Revolving Advances, if any, required to cause the total
       outstanding Tranche B Multicurrency Revolving Advances to equal GBP
       19,000,000 (or the Equivalent Amount thereof) or less (and the Tranche B
       Multicurrency Revolving Commitments shall be decreased accordingly); (ii)
       on 31st December, 2001, the Borrower shall repay such portion of the
       outstanding Tranche B Multicurrency Revolving Advances, if any, required
       to cause the total outstanding Tranche B Multicurrency Revolving Advances
       to equal GBP 16,000,000 (or the Equivalent Amount thereof) or less (and
       the Tranche B Multicurrency Revolving Commitments shall be decreased
       accordingly); and (iii) on 31st December, 2002, the Borrower shall repay
       all remaining outstanding Tranche B Multicurrency Revolving Advances.

6.2.5  Subject to the terms of this Agreement, if any Tranche B Multicurrency
       Revolving Advance (the "New Revolving Advance") is to be made to the
       Borrower on the day on which another Tranche B Multicurrency Revolving
       Advance denominated in the same currency (the "Maturing Revolving
       Advance") is due to be repaid (the "Revolving Maturity Date") by the
       Borrower then (subject to there being no Event of Default or Potential
       Event of Default), as between each Lender and the Borrower, the amount to
       be repaid by the Borrower by way of Maturing Revolving Advance shall be
       set off against the amount of the New Revolving Advance to be advanced by
       each Lender (in respect of its participation) and the party to whom the
       smaller amount is to be paid shall advance or repay (as appropriate) to
       the party to whom the larger amount is to be paid the difference between
       the two amounts on the Revolving Maturity Date.

7.     PREPAYMENT AND CANCELLATION


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7.1    Voluntary Prepayments

7.1.1  Subject to the order of application set forth in Clause 7.3.1, the
       Borrower may voluntarily prepay the whole or part of any Advance on the
       last day of an Interest Period (or on any other Business Day subject to
       payment of any breakage costs thereby incurred by any Lender in
       accordance with Clause 27.1) relating thereto provided that the Agent has
       received from the Borrower not less than ten Business Days' notice of the
       proposed date and the amount of the prepayment.

7.1.2  If the Loans are to be prepaid voluntarily in part, the aggregate amount
       of the partial prepayment must be a minimum of GBP 1,000,000 or the
       Equivalent Amount thereof and an integral multiple of GBP 500,000 or the
       Equivalent Amount thereof.

7.1.3  A prepayment made in accordance with the terms of this Clause 7 may be
       made without premium or penalty.

7.2    Mandatory Prepayments

7.2.1  Asset Disposals

       If the Borrower disposes of an asset (other than:-

       (a)    a disposal permitted by Clauses 13.2.8(a), (b) or (c), or

       (b)    disposals permitted by Clauses 13.2.8(d) and (e) up to an
              aggregate amount of Net Cash Proceeds for all such disposals
              described in this sub-clause (b) of GBP 2,500,000 (or its
              equivalent) following the date of this Agreement),

       the Net Cash Proceeds of such disposal shall be applied by the Borrower
       as promptly as practicable in prepayment of the outstandings under this
       Agreement in accordance with Clause 7.3.1 below.

7.2.2  Cashflow

       Before the Achievement Date only, the Borrower will once per annum make a
       prepayment to be applied against the outstandings under this Agreement in
       accordance with Clause 7.3.1 below within 120 days of the expiry of each
       Accounting Reference Period (beginning with the Accounting Reference
       Period ended 31st December 1998) in the amount of 50% of the aggregate of
       the unconsolidated 


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       Cashflow, without allowing for any duplication, of each Obligor
       (determined in accordance with the respective applicable Approved
       Accounting Principles) for the Accounting Reference Period then ended, if
       a positive number.

7.2.3  Change of Control

       Immediately upon a Change of Control:

       (a)    the Borrower will prepay all Advances, accrued interest thereon
              and all other sums payable under this Agreement and the other
              Finance Documents; and

       (b)    the unborrowed amount of all Facilities will be cancelled and the
              Commitment of each Lender in respect of each Facility shall be
              reduced to zero.

7.3    Prepayments; Order of Application

7.3.1  Partial prepayments made pursuant to Clauses 7.1 and 7.2 will be applied
       by the Borrower first, to the permanent prepayment of the Tranche A Term
       Loan (to be applied pro-rata against the scheduled remaining repayments
       thereof); and second, to the permanent prepayment of the Tranche B
       Multicurrency Revolving Advances.

7.3.2  Amounts applied in permanent repayment of the Tranche B Multicurrency
       Revolving Advances may not be redrawn and, upon any such prepayment, each
       Lender's Tranche B Multicurrency Revolving Commitment shall be reduced
       proportionately.

7.4    Prepayments during Interest Periods

7.4.1  Prepayments pursuant to Clauses 7.1, 7.2 and 7.3 applied to the
       obligations of the Borrower hereunder shall be subject to payment of any
       breakage costs incurred by any Finance Party, calculated in accordance
       with Clause 27.1 (General Indemnity and Breakage Costs). If requested by
       the Borrower, the Agent shall deposit the proceeds of prepayment in an
       interest-bearing account established on terms (including terms as to
       security) in all respects satisfactory to the Agent until the end of the
       Interest Period then current and apply such funds (together with any
       interest accrued thereon) toward the required prepayment on the last day
       of such Interest Period.

7.5    Cancellation


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7.5.1  The Borrower may cancel the whole or any part (but if in part, in a
       minimum amount of GBP 1,000,000 or the Equivalent Amount thereof and in
       integral multiples of GBP 500,000 or the Equivalent Amount thereof) of
       the Tranche B Multicurrency Revolving Facility undrawn when the notice of
       cancellation takes effect if it gives three Business Days' written notice
       of cancellation to the Agent. Cancellation made in accordance with the
       terms of this Clause 7 may be made without penalty.

7.5.2  Upon each cancellation of the Tranche B Multicurrency Revolving Facility,
       the Borrower shall be required to make such repayments thereof as are
       necessary so that the Tranche B Multicurrency Revolving Advances
       outstanding at the time of the cancellation do not exceed the total
       Tranche B Multicurrency Revolving Commitments after giving effect to such
       cancellation. Upon any such cancellation taking effect the maximum amount
       of the Tranche B Multicurrency Revolving Facility shall be accordingly
       reduced and the amount of each Lender's Tranche B Multicurrency Revolving
       Commitment (if any) shall be reduced proportionately.

7.6    General

7.6.1  No prepayment may be made except at the times and in the manner expressly
       provided by this Agreement.

7.6.2  No amount prepaid in respect of the Tranche A Term Facility may be
       subsequently re-drawn.

7.6.3  All prepayments shall be made together with interest accrued thereon up
       to the date of prepayment and any other amounts then due and payable
       under any Finance Document.

7.6.4  The Agent shall notify the Lenders promptly upon receipt by it of a
       notice of prepayment.

7.6.5  All notices of prepayment and all notices of cancellation given by the
       Borrower are irrevocable.

8.     INTEREST

8.1    Interest Rate

8.1.1  Each Advance will bear interest during each Interest Period applicable to
       that Advance at the rate per annum determined by the Agent to be the sum
       of (a) the applicable Margin, (b) LIBOR for such Interest Period, 


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       and (c) in the case of Advances denominated in GBP or another currency
       subject to Mandatory Liquid Asset Costs, Mandatory Liquid Asset Costs.

8.1.2  Interest will be calculated on the basis of actual days elapsed and a
       360-day year (other than interest in respect of Advances denominated in
       GBP, which will be calculated on the basis of a year of 365 days), and
       will accrue from day to day from, and including, the first day of each
       Interest Period.

8.1.3  If requested to do so, each Reference Lender shall use its reasonable
       endeavours to supply a quotation to the Agent for the purposes of
       determining LIBOR for a particular Interest Period. If any Reference
       Lender does not do so, the relevant arithmetic mean shall be determined
       on the basis of the quotations supplied by the remaining Reference
       Lenders. At such time as there are three Reference Lenders, if no, or
       only one, Reference Lender supplies a quotation, Clause 8.5 shall apply;
       provided that if there are only two Reference Lenders and one supplies a
       quotation, Clause 8.5 shall not apply in such case.

8.2    Payment of Interest

       The Borrower will pay interest accrued on each Advance to the Agent for
       the account of the Lenders in arrears on the last day of each Interest
       Period applicable to that Advance, provided that where such Interest
       Period is of a duration of longer than three months, accrued interest in
       respect of the relevant Advance shall be paid every three months during
       such Interest Period and on the last day of such Interest Period.

8.3    Selection of Interest Periods

8.3.1  Subject to Clause 3.5.(e), the duration of each Interest Period will be a
       period of one, two, three or six months (or such other period as may be
       agreed between the Borrower and all of the Lenders) as notified by the
       Borrower to the Agent not later than 10.00 a.m. three Business Days prior
       to the commencement of such Interest Period, provided that:-

       (a)    the first Interest Period in relation to an Advance will commence
              on the Drawdown Date relating thereto and each subsequent Interest
              Period relating to such Advance (or part thereof) will commence on
              the expiry of the preceding Interest Period relating thereto;


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       (b)    if the Borrower fails to select an Interest Period, then, subject
              as provided in this Clause 8.3, the Borrower will be deemed to
              have selected an Interest Period of three months; and

       (c)    if all or part of a Tranche A Term Advance is required to be
              repaid on a Repayment Date to ensure that the Borrower complies
              with its obligations under Clause 6.1.1 and if an Interest Period
              relative to that Advance would, but for the operation of this
              sub-clause (c), extend beyond such Repayment Date, then if
              necessary such Advance shall be split into two separate Advances
              (such additional Advance not to be counted for the purposes of
              sub- clause (d) below), one of which shall be in an amount equal
              to the amount required to be repaid and having an Interest Period
              commencing upon the expiry of the immediately preceding Interest
              Period and expiring on the relevant Repayment Date, the other
              Advance being for the balance of the amount of the original
              Advance; and

       (d)    the Borrower will not be entitled to select more than three
              concurrent Interest Periods in relation to the Advances.

8.3.2  If any Interest Period would, but for this Clause 8.3.2, end on a day
       which is not a Business Day, that Interest Period shall be extended to
       the next succeeding Business Day unless the result of such extension
       would be to carry such Interest Period into another calendar month, in
       which event such Interest Period shall end on the last preceding Business
       Day.

8.3.3  No Interest Period for any Advance shall expire after the Final Repayment
       Date.

8.3.4  The Agent will notify:-

       (a)    the Lenders of each Interest Period applicable to each Advance
              promptly upon the same being determined; and

       (b)    the Lenders and the Borrower of the rate of interest applicable to
              such Interest Period as soon as it is determined under this
              Agreement.

8.4    Interest on Unpaid Sums


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8.4.1  If the Borrower fails to pay any sum due from it under this Agreement or
       any other Finance Document on its due date (an "unpaid sum"), the
       Borrower will pay default interest on such unpaid sum from its due date
       to the date of actual payment (after as well as before judgement or
       decree) at a rate (the "Default Rate") determined by the Agent to be 2
       per cent per annum above:-

       (a)    if the unpaid sum is principal which has fallen due prior to the
              expiry of the relevant Interest Period, the rate applicable to
              such principal immediately prior to the date it so fell due (but
              only for the period from such due date to the end of the relevant
              Interest Period); or

       (b)    in any other case (including principal falling within (a) above
              once the relevant Interest Period has expired), the rate which
              would be payable if the unpaid sum was an Advance made for a
              period equal to the period of non-payment divided into successive
              Interest Periods of such duration as shall be selected by the
              Agent (a "Default Interest Period").

8.4.2  Default interest will be payable by the Borrower on demand by the Agent
       and will be compounded at the end of each Default Interest Period.

8.4.3  The Agent will promptly notify the Borrower and the Lenders of each
       determination of the Default Rate and each selection of a Default
       Interest Period.

8.5    Market Disruption

8.5.1  If prior to the commencement of an Interest Period (an "Affected Interest
       Period"):-

       (a)    the Agent, after consultation with the Lenders, determines that,
              by reason of circumstances affecting the London interbank market
              or the financial markets generally, adequate and fair means do not
              or will not exist for ascertaining the interest rate applicable to
              the Affected Interest Period; or

       (b)    Lenders whose Relevant Amounts exceed 51% of Relevant Amounts of
              all Lenders notify the Agent that LIBOR would not accurately
              reflect the cost to such Lenders of making or maintaining their
              respective Participations in the relevant Advance during the
              Affected Interest Period; or


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       (c)    the appropriate page of the Telerate Display Screen does not list
              any appropriate quotations and (i) at such time as there are three
              Reference Lenders none or only one of the Reference Lenders has
              notified a rate to the Agent for the purposes of determining LIBOR
              for the Affected Interest Period, or (ii) at such time as there
              are two Reference Lenders none of the Reference Lenders has
              notified a rate to the Agent for the purposes of determining LIBOR
              for the Affected Interest Period;

       the Agent shall give notice of such event to the Borrower and the Lenders
       (a "Suspension Notice"). If such Suspension Notice shall be given prior
       to the receipt by the Agent of a Drawdown Request, the Borrower's right
       to borrow and issue a Drawdown Request in respect of Advances hereunder
       shall be suspended during the continuance of such circumstances.

8.5.2  If at the time of the Suspension Notice a Drawdown Request has been given
       pursuant to Clause 5.1.1, such Drawdown Request shall, unless the
       Borrower and the Agent (after consultation with the Lenders) otherwise
       agree, be deemed to have been cancelled and the Advance concerned shall
       not be made.

8.5.3  Subject to Clause 8.5.4, during the 21 days following the giving of the
       Suspension Notice, the Agent, the Borrower and the Lenders shall
       negotiate in good faith in order to arrive at a mutually acceptable
       substitute basis for calculating the alternative interest rate or (as the
       case may be) an alternative basis for the relevant Lender to fund or
       continue to fund the affected Advance during the Affected Interest Period
       on the basis that the net return to the Lenders or the relevant Lender
       shall be no less than had the event described in Clause 8.5.1 not
       occurred. If within such 21 day period such parties shall agree in
       writing upon a substitute basis, such substitute basis shall apply in
       accordance with its terms. If such parties fail to agree on a substitute
       basis within such 21 day period, the Agent (after consultation with the
       Lenders or, as the case may be, the relevant Lender) shall certify to the
       Borrower (such certificate to be conclusive in the absence of manifest
       error, and binding on all concerned) the basis upon which interest in
       relation to the Affected Interest Period is to be fixed or (as the case
       may be) the basis upon which the relevant Lender will fund or continue to
       fund its participation in the Advance during the Affected Interest
       Period. Such basis (in relation to the said rate of interest) may include
       the substitution of the cost of 


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       funds to such Lenders from other sources and for different funding
       periods, plus the Margin (plus, in the case of Advances in GBP or another
       currency subject to Mandatory Liquid Asset Costs, Mandatory Liquid Asset
       Costs), and may be retroactive to the beginning of the Affected Interest
       Period. Such interest shall be calculated at the rate specified in the
       Agent's certificate.

8.5.4  Notwithstanding the foregoing, the Borrower may, at any time after the
       Agent shall have set a substitute funding procedure or interest rate or
       rates pursuant to Clause 8.5.3 and for so long as such funding procedure
       or interest rate or rates continue(s) to be applicable, give to the Agent
       not less than five Business Days' notice (which shall be irrevocable) of
       its intention to prepay the whole (but not part only) of the Advance
       affected, in which event the Borrower shall pay:-

       (a)    on the date specified in such notice to the Agent for the account
              of the Lenders the principal amount of the Advance affected
              together with interest accrued thereon at the applicable rate to
              the date of actual prepayment; and

       (b)    to each Lender on demand such amount (if any) as such Lender may
              certify should be paid to it pursuant to Clause 26.1 (General
              Indemnity and Breakage Costs).

9.     PAYMENTS

9.1    Place and Time

9.1.1  All payments to be made by any Obligor or any Lender under the Finance
       Documents are to be made in full, without any deduction or withholding
       for or on account of any Taxes, to the Agent not later than 11.00 a.m. on
       the due date therefor to such account as the Agent specifies by written
       notice for this purpose, in immediately available and freely transferable
       Same Day Funds in the relevant currency.

9.1.2  Subject to Clause 9.1.3, each payment received by the Agent pursuant to
       Clause 9.1.1 for the account of another person will be made available by
       the Agent to that person for value on the same day by transfer to such
       bank account as that person has previously notified to the Agent by not
       less than three Business Days' prior notice.


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9.1.3  Where a sum is to be paid under the Finance Documents for the account of
       another person, the Agent will not be obliged to make any such sum
       available to that person until it has been able to establish to its
       satisfaction that it has actually received such sum, but shall be free to
       do so and if it does so and it proves to be the case that it has not
       actually received the sum it paid out, then such person will on request
       ensure that the amount so made available is refunded to the Agent and
       such person shall be liable (1) to pay to the Agent interest on the
       amount in question at the rate determined by the Agent to be equal to the
       cost to the Agent of funding such amount for the period from payment out
       by the Agent until refund to the Agent thereof and (2) to indemnify the
       Agent against any additional cost or loss it may have suffered or
       incurred by reason of it having paid out such sum prior to it having
       received the same.

9.2    No Deductions

       All payments made by any Obligor under the Finance Documents (whether of
       principal, interest, acceptance commission, fees or otherwise) shall be
       paid in full without set-off or counterclaim and not subject to any
       condition.

9.3    Taxes

9.3.1  All payments by the Obligors under the Finance Documents are to be made
       in full without any deduction or withholding for or on account of any
       Taxes unless the deduction or withholding is required by law in which
       event the relevant Obligor Borrower will:-

       (a)    ensure that the deduction or withholding does not exceed the
              minimum amount legally required;

       (b)    pay to the relevant Taxation or other authorities within the
              period for payment permitted by the applicable law such amount as
              is required to be paid in consequence of the deduction (including,
              but without prejudice to the generality of the foregoing, the full
              amount of any deduction from any additional amount paid pursuant
              to Clause 9.3.2); and

       (c)    deliver to the relevant Finance Parties within 30 days from the
              date on which the payment of such withholding tax or deduction was
              due, the documents evidencing the payment of such aforementioned
              withholding tax or deductions; and


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       (d)    indemnify each of the Finance Parties against any losses or costs
              incurred by it by reason of (i) any failure on the part of such
              Obligor to make any deduction or withholding or (ii) any such
              additional amount not being paid on the due date for payment
              thereof.

9.3.2  Subject to Clause 9.3.3, if any deduction or withholding for or on
       account of Taxes or any other deduction from any payments made or to be
       made by the relevant Obligor, or by the Agent to any other Finance Party,
       under any of the Finance Documents is required by law, then the Obligor
       shall pay to the Finance Party concerned an additional amount being the
       amount required to procure that the aggregate net amount received by that
       Finance Party will equal the full amount which would have been received
       by it had no such deduction or withholding or other deduction been made.

9.3.3  No additional amount will be payable to a Lender under Clause 9.3.2 in
       respect of Taxes to the extent that such additional amount becomes
       payable as a result only of (i) a Lender not having been a Qualifying
       Lender at the time it became a Lender, or (ii) a Lender having ceased to
       be a Qualifying Lender by any action on its part, or (iii) a change in
       the Lending Office of the relevant Lender, unless (A) such change is
       requested by the Borrower, or (B) under the relevant Tax laws,
       regulations, treaties or rules in effect at the time of the change in
       Lending Office, such additional amount would not have been payable.

9.3.4  If the Borrower is obliged to pay an amount under Clause 9.3.1, the
       Borrower may prepay in whole (but not in part) and without penalty
       (subject to Clause 27) all Advances made available to it by the affected
       Lender, upon the Borrower giving not less than three Business Days' prior
       written notice to the Agent and the affected Lender, provided that such
       notice is given within 30 days of the Borrower becoming aware that it
       would be obliged to pay such amount. The liability of such Lender to make
       any further Advances or other extensions of credit available to the
       Borrower (and such lender's Commitments) shall automatically be cancelled
       on the giving of such notice.

9.3.5  If any of the Lenders determines, in its absolute discretion, that it has
       received, realised, utilised and retained a Tax benefit by reason of any
       deduction or withholding in respect of which an Obligor has made an
       increased payment or paid any indemnifying amount or 


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       compensating sum under this Clause 9.3, such Lender shall, provided that
       the Agent and each Lender has received all amounts which are then due and
       payable by an Obligor under any of the Finance Documents, promptly pay to
       the Borrower (to the extent that such Lender can do so without
       prejudicing the amount of such benefit or repayment and the right of such
       Lender to obtain any other benefit, relief or allowance which may be
       available to it) such amount, if any, as such Lender, in its absolute
       discretion shall determine will leave such Lender in no worse position
       than it would have been in if the deduction or withholding had not been
       required, provided that:-

       (a)    each Lender shall have an absolute discretion as to the time at
              which and the order and manner in which it realises or utilises
              any Tax benefit and shall not be obliged to arrange its business
              or its Tax affairs in any particular way in order to be eligible
              for any credit or refund or similar benefit;

       (b)    no Lender shall be obliged to disclose any information regarding
              its business, Tax affairs or Tax computations;

       (c)    if a Lender has made a payment to the Borrower pursuant to this
              Clause 9.3.5 on account of any Tax benefit and it subsequently
              transpires that such Lender did not receive that Tax benefit, or
              received a lesser Tax benefit, the Borrower shall, on demand, pay
              to such Lender such sum as the relevant Lender may determine as
              being necessary to restore its after-Tax position to that which it
              would have been had no adjustment under this Clause 9.3.5 been
              necessary; and

       (d)    no Lender shall be obliged to make any payment under this Clause
              9.3.5 if, by doing so, it would contravene the terms of any
              applicable law or any notice, direction or requirement of any
              governmental or regulatory authority (whether or not having the
              force of law).

9.4    Payments on Business Days

       Subject to Clauses 6.2 and 8.3.2, if any sum would otherwise become due
       for payment pursuant to any of the Finance Documents on a day which is
       not a Business Day, such sum shall become due on the next succeeding
       Business Day unless that day falls in the next calendar month, in 


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       which case the sum shall become due on the preceding Business Day and all
       sums payable under any of the Finance Documents calculated by reference
       to any period of time shall be recalculated on the basis of such
       extension in time (or reduction thereof).

9.5    Accounts

9.5.1  Each Lender shall maintain an account or accounts recording the amounts
       from time to time lent by, owing to and paid to such Lender pursuant to
       the Finance Documents, which shall, as between such Lender and the
       relevant Obligor, be prima facie evidence of such amounts.

9.5.2  The Agent will maintain a memorandum account showing the principal amount
       of all Advances for the time being outstanding hereunder and all payments
       with respect thereto made by the Obligors from time to time pursuant to
       this Agreement.

9.6    Currency

9.6.1  A repayment or prepayment of an Advance or any part of an Advance is
       payable in the currency in which the Advance was denominated on the date
       it was made.

9.6.2  Interest and fees in respect of an Advance are payable in the currency in
       which the relevant amount of the relevant Advance in respect of which it
       is payable is denominated. Fees in respect of Commitments hereunder shall
       be payable in GBP.

9.6.3  Amounts payable in respect of costs, expenses and Taxes and the like are
       payable in the currency in which they are incurred.

9.6.4  Any other amount payable under this Agreement is, except as otherwise
       provided in this Agreement, payable in GBP.

10.    CHANGE IN CIRCUMSTANCES

10.1   Increased Costs

10.1.1 If the effect of any implementation of, change in or introduction or
       making after the date of this Agreement of, any law, regulation, treaty
       or official directive or official request or guidance applicable to any
       Lender or any affiliate, including without limitation, a holding company,
       (an "Affected Lender") (whether or not having 


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       the force of law) or any change in the interpretation or application
       thereof or compliance by such Affected Lender, with the same (including
       without limitation those relating to Taxation, reserve asset, special
       deposit, cash ratio, liquidity or capital adequacy requirements or any
       other form of banking or monetary controls) is to:-

       (a)    impose an additional cost on the Affected Lender as a result of it
              having entered into any of the Finance Documents or making or
              maintaining its participation in any Advance or of it performing
              its obligations under the Finance Documents; or

       (b)    reduce any amount received or receivable by the Affected Lender
              under the Finance Documents or reduce the effective return on its
              capital or any class thereof; or

       (c)    result in the Affected Lender making any payment or foregoing any
              interest or other return on or calculated by reference to any
              amount received or receivable by the Affected Lender from any
              other party under any of the Finance Documents,

       each such increased cost, reduction, payment, foregone interest or other
       return being hereafter referred to in this Clause 10.1 as an "increased
       cost"), then:-

(1)    the Affected Lender will notify the Borrower and the Agent of such event
       promptly upon its becoming aware of the same; and

(2)    upon demand from time to time by the Affected Lender, the Borrower will
       pay to the Affected Lender such amount as the Affected Lender shall
       determine to be necessary to compensate the Affected Lender on an
       after-tax basis for such increased cost (or the portion of such increased
       cost as is in the reasonable opinion of the Affected Lender attributable
       to its entering into the Finance Documents or of making or maintaining
       its participation in any Advance or of maintaining its Commitment).

10.1.2 The certificate of an Affected Lender specifying the amount of
       compensation payable under Clause 10.1.1 and containing reasonable detail
       as to how such amount was calculated will, in the absence of manifest
       error, be conclusive.

10.1.3 The Borrower will not be obliged to compensate any Affected Lender
       pursuant to Clause 10.1.1 in respect of any increased cost:-


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(a)    attributable to a change in the rate of Tax on the overall net income of
       the Affected Lender; or

(b)    compensated for by the operation of Clause 9.3 (Taxes); or

(c)    incurred in consequence of the implementation in whole or in part of the
       International Convergence of Capital Measurements and Capital Standards
       dated July 1988 published by the Basle Committee on Banking Regulations
       and Supervisory Practices (the "Guidance"), except to the extent that a
       higher level of capital adequacy is imposed than that stipulated in the
       Guidance as at the date of this Agreement;

(d)    including within the definition of Mandatory Liquid Asset Costs; or

(e)    until the calculation of such cost set forth in the certificate referred
       to in Clause 10.1.2 has been received by the Borrower.

10.2   Illegality

       If the effect of any implementation of, change in, or introduction or
       making after the date of this Agreement of, any law, regulation, treaty
       or official directive or official request or guidance applicable to any
       Lender or any affiliate, including without limitation, a holding company,
       (a "Restricted Lender") (whether or not having the force of law) in any
       jurisdiction applicable to such Restricted Lender is to prohibit such
       Restricted Lender, or make it illegal for such Restricted Lender, to make
       available or to maintain its participation in any Advance or maintain its
       Commitment, then such Restricted Lender will give written notice to that
       effect to the Agent and the Borrower, specifying in reasonable detail the
       obligations the performance of which is prohibited and the relevant law,
       regulation, treaty, directive, request or guideline, whereupon:-

       (a)    to the extent of such prohibition or illegality, the Borrower
              shall forthwith prepay the Restricted Lender's participation in
              all Advances then outstanding together with all interest accrued
              thereon and all other amounts due to the Restricted Lender under
              this Agreement (including pursuant to Clause 26 (Indemnities));
              and/or


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       (b)    to the extent of such prohibition or illegality, the Restricted
              Lender's undrawn Commitment (if any) shall be cancelled forthwith.

10.3   Mitigation

       If circumstances arise in relation to a particular Lender which would, or
       may, result in:-

       (a)    an obligation to pay an additional amount under Clause 9.3.2
              (Gross-Up); or

       (b)    a demand for compensation pursuant to Clause 10.1 (Increased
              Costs); or

       (c)    an obligation to repay or the cancellation of an undrawn
              Commitment under Clause 10.2 (Illegality);

       then, without in any way limiting, reducing or otherwise qualifying the
       obligations of the Borrower under any of the Clauses referred to above,
       such Lender will promptly after becoming aware thereof notify the Agent
       and the Borrower thereof and, except as set out in the provisos in
       paragraphs (y) and (z) below, in consultation with the Agent and the
       Borrower, take such steps as may be reasonably open to it to mitigate the
       effects of such circumstances including (but without limitation):-

(i)    changing its Lending Office for the purposes of this Agreement; or

(ii)   transferring its rights and obligations hereunder pursuant to Clause 25.2
       or 25.3 to a bank or financial institution acceptable to the Borrower and
       the Agent which is willing to participate in the Facilities in its place;

       provided that (y) the Lender concerned will not be obliged to take any
       action under sub-paragraph (i) above if to do so would or might (in its
       opinion) have an adverse effect upon its business, operations or
       financial condition or cause it to incur liabilities (including any
       material costs and expenses) or obligations (including Taxation) which
       (in its opinion) are material or would reduce its return in relation to
       its participation in the Facilities and (z) such Lender will not be
       obliged to take the action referred to in sub-paragraph (ii) above unless
       the Borrower indemnifies it by means of an indemnity in form and content
       satisfactory to such Lender against any liabilities or obligations
       reasonably incurred as a result of taking such action.


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11.    FEES, EXPENSES AND STAMP DUTIES

11.1   Fees

11.1.1 The Borrower will pay to the Agent the following fees:-

(a)    for the account of each Lender a commitment fee during the Availability
       Period for each respective Facility which will:-

(i)    be computed at a rate per annum equal at all times to one-half of the
       Margin and on the daily aggregate undrawn, uncancelled amount of the
       Total Commitments;

(ii)   accrue from day to day and be calculated on the basis of a 365 day year
       and the actual number of days elapsed;

(iii)  be payable quarterly in arrears on the last day of each successive
       calendar quarter, on each drawing under the Tranche A Term Facility and
       on the termination or lapse of the Availability Period to the extent no
       drawing under the Tranche A Term Facility is made concurrent with such
       termination or lapse; and

(b)    for its own account or as otherwise specified in the Fees Letter, such
       arrangement, agency and other fees at the times and otherwise in
       accordance with the terms of the Fees Letter.

11.1.2 All fees payable under the Finance Documents are exclusive of any VAT or
       other similar tax chargeable upon or in connection with such fees. If any
       VAT or other similar Tax is or becomes so chargeable, such Tax will be
       paid by the Borrower at the same time as the relevant fee itself is paid.

11.1.3 The Borrower authorises the Agent to discharge the fees due upon Initial
       Drawdown under Clauses 11.1.1 (a) and (b) from the proceeds of Advances
       made upon Initial Drawdown under any Facility.

11.2   Expenses

11.2.1 The Borrower will (subject to the limitations set forth in the Fees
       Letter) on demand pay and reimburse to the Agent and the Security Agent,
       on the basis of a full indemnity, all reasonable costs and expenses
       (including legal fees, due diligence expenses, recordation fees and other
       out-of-pocket expenses and any VAT or other similar Tax thereon) incurred
       by the Agent or the Security Agent 


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       in connection with the negotiation, preparation, recordation, execution
       and completion of each of the Finance Documents, and all documents,
       matters and things referred to in the Finance Documents or incidental to
       any of the Finance Documents.

11.2.2 The Borrower will on demand pay and reimburse to the Agent and the
       Security Agent, on the basis of a full indemnity, all reasonable costs
       and expenses (including reasonable legal fees, recordation fees and other
       out-of-pocket expenses and any VAT or other similar Tax thereon) incurred
       by the Agent or the Security Agent in connection with:-

(a)    any variation, recordation, amendment, supplement, restatement, waiver,
       consent or suspension of rights (or any proposal for any of the same)
       relating to any of the Finance Documents (and documents, matters or
       things referred to therein); and

(b)    the investigation of any Event of Default or Potential Event of Default,
       provided that the relevant Finance Party had reasonable grounds to
       believe that such Event of Default or Potential Event of Default had
       occurred.

11.2.3 The Borrower will on demand pay and reimburse to each Finance Party, on
       the basis of a full indemnity, all costs and expenses (including
       reasonable legal fees, recordation fees and other out-of-pocket expenses
       and any VAT or other similar Tax thereon) incurred by such Finance Party
       in connection with the preservation, enforcement or the attempted
       preservation or enforcement of any Finance Document or of such Finance
       Party's rights under any of the Finance Documents (and documents referred
       to therein).

11.3   Stamp Duties, etc.

       The Borrower will:-

       (a)    pay, and on demand indemnify each Finance Party from and against
              any liability for, any stamp duty, documentary, registration and
              other duties and Taxes (if any) which are or may hereafter become
              payable in connection with the entry into, performance,
              recordation, execution or enforcement of any of the Finance
              Documents or to which any of the Finance Documents may otherwise
              be or become subject or give rise; and


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       (b)    on demand indemnify each of the Finance Parties from and against
              any losses or liabilities which they may incur as a result of any
              delay or omission by the Borrower to pay any such duties or Taxes.

12.    REPRESENTATIONS AND WARRANTIES

12.1   Reliance and Effective Time

12.1.1 Each Obligor acknowledges that each Finance Party has or will have
       entered into this Agreement and the other Finance Documents to which it
       is a party and participated in the Advances in full reliance on
       representations in the terms set out in the following provisions of this
       Clause 12. Subject to Clause 12.1.2, each Obligor represents and warrants
       to each Finance Party in the terms set forth in Clauses 12.2 to 12.23
       inclusive with reference to itself and, where appropriate, its
       subsidiaries.

12.1.2 The representations and warranties in this Clause 12 will be deemed
       initially made on the date of this Agreement and repeated on the date of
       delivery of each Drawdown Request, on each Drawdown Date and on each
       Interest Payment Date thereafter by reference to the facts and
       circumstances existing on each such day, except that:

(a)    each reference to financial statements in Clause 12 shall be construed as
       a reference to the then latest available financial statements of the
       relevant Obligor; and

(b)    those representations and warranties which are expressly stated to relate
       to an earlier date or time shall be deemed repeated only by reference to
       the facts and circumstances existing at that earlier date or time.

12.2   Incorporation

       It is duly incorporated or organised and validly existing with limited
       liability under the laws of the country or other jurisdiction of its
       incorporation or organisation, and has the power to own its assets and
       carry on its business as it is being conducted or is proposed to be
       conducted.

12.3   Power and Authority

       It has all necessary power and authority to enter into and perform all
       its obligations under the Finance Documents to which it is expressed to
       be a party, has 


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       taken all necessary action to authorise the execution (if appropriate,
       under seal or as a deed), delivery and performance by it of each Finance
       Document and other document referred to therein to which it is expressed
       to be a party or signatory, and (in the case of the Borrower only) has
       taken all necessary action to authorise the borrowings by it under this
       Agreement.

12.4   No Contravention

12.4.1 The execution, delivery and performance of the Finance Documents to which
       it is a party is not now and will not:-

       (a)    violate, conflict with, or cause a breach or default under, its
              organisational documents, any provision of any existing law,
              regulation, statute, judgement, decree, order, license, permit or
              consent applicable to it or its assets or of any agreement,
              mortgage, contract, instrument or other undertaking to which it is
              party, which is binding upon it or under which it or any of its
              assets may be bound or affected; or

       (b)    will not oblige it to create any Security Interest over all or any
              of its assets other than any Security Interest under the Security
              Documents.

12.4.2 Borrowings by the Borrower under this Agreement up to and including the
       maximum amount available hereunder will not cause any limit on borrowings
       (whether imposed by statue, regulation, agreement or otherwise), or on
       the powers of its board of directors, to be exceeded.

12.5   Authorisations and Consents

       All consents, licenses, approvals, authorisations and notifications
       (whether corporate, official or otherwise) required to be obtained or
       made by it in connection with the entry into, validity, performance and
       enforceability of each of the Finance Documents to which it is a party
       have been unconditionally obtained and are in full force and effect.

12.6   Enforceability; Ranking

       Its obligations under the Finance Documents to which it is a party
       constitute its legal, valid, binding and enforceable obligations and are
       in full force and effect, except (in the case of enforceability) as
       limited by the Reservations, and such obligations, to the extent not
       secured by any Security Interest, ranks and will continue 


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       to rank at all times at least pari passu with all its unsecured and
       unsubordinated obligations (subject to the preference of certain
       obligations in the liquidation, bankruptcy or other analogous proceedings
       in respect of it by mandatory operation of applicable law).

12.7   Litigation

       It is not involved in any pending or, to the best of its knowledge,
       threatened litigation, arbitration or administrative proceeding, nor is
       there subsisting any unsatisfied judgement or award given against it by
       any court, board of arbitration or other body, which is reasonably likely
       to result in liability to any Obligor which has or is reasonably likely
       to have a Material Adverse Effect.

12.8   Accounts

12.8.1 The consolidated or unconsolidated financial statements of each Obligor
       most recently delivered to the Agent pursuant to Clause 4.1.1 or 13.3, as
       the case may be, including any notes thereto:-

(a)    have been prepared in accordance with the respective relevant Approved
       Accounting Principles consistently applied, except to the extent
       specified therein; and

(b)    give a true and fair view of the consolidated or unconsolidated (as the
       case may be) financial condition of the relevant persons as at the
       respective dates to which they were drawn up;

       and in each case set forth all material actual or contingent liabilities
       then existing required to be set forth therein in accordance with the
       relevant Approved Accounting Principles consistently applied subject in
       the case of any unaudited interim financial statements, to changes
       resulting from normal year-end audit and other adjustments.

12.9   No Material Adverse Effect

       No event or matter having or likely to have a Material Adverse Effect has
       occurred since 31st December, 1996.

12.10  Security Interests

       Except as permitted by Clause 13.2.10, no Security Interest exists on the
       date of this Agreement on the 


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       undertaking, property or assets, present or future, of the Borrower or
       any of its subsidiaries.

12.11  No Defaults

       Unless notified to the Agent under Clause 13.3.1, no Event of Default or
       Potential Event of Default has occurred and is continuing and no event
       has occurred (which has not been remedied or waived) which constitutes a
       default under or in respect of any agreement, instrument, deed or
       document to which it is a party or by which it or any of its assets may
       be bound or affected being a default which has or is reasonably likely to
       have a Material Adverse Effect, and no event has occurred (which has not
       been remedied or waived) which, with the giving of notice which may
       validly be given and/or the lapse of any grace period and/or giving of
       any certificate or statement which may validly be given and/or making of
       any determination which may validly be made and/or fulfilment of any
       other condition (which notice, grace period, certificate, statement,
       determination or condition is in any case specified or referred to in the
       relevant agreement, instrument, deed or document), will constitute any
       such default which is reasonably likely to have a Material Adverse
       Effect.

12.12  Compliance with Laws

       It is in compliance with all laws, regulations, statutes, judgements,
       orders, licenses, permits or consents applicable to it or its assets,
       except any non-compliance which does not have and is not reasonably
       likely to have a Material Adverse Effect.

12.13  Ownership of Assets, Licenses and Agreements for Business Operations;
       Intellectual Property

12.13.1  It has good (and in the case of Scottish property, valid and
         marketable) title to, or valid leasehold or other valid right to use,
         all its material assets (including without limitation those relating to
         the Annan Facility and the Dudley Facility) to the extent required to
         conduct the Business or the part thereof which it conducts.

12.13.2  All licenses, consents and authorisations (including without
         limitation, all such licenses, consents and authorisations required to
         be obtained from the United States Food and Drug Administration, the
         Medicines Control Agency and any other regulatory body having
         jurisdiction over the manufacture and/or


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         sale of pharmaceutical products in the United States or the United
         Kingdom) have been obtained which are necessary for the carrying on of
         its Business or the part thereof which it conducts, and all such
         licenses, consents and authorisations are in full force and effect, and
         there are no circumstances known to it which indicate that any of such
         licenses, consents and authorisations is reasonably likely to be
         revoked or varied or amended in whole or in part, except to the extent
         that the absence, non-effectiveness, revocation, variation or amendment
         of any such license, consent or authorisation would not have and would
         not be reasonably likely to have a Material Adverse Effect.

12.13.3  The Obligors own or have licensed to them all Intellectual Property
         rights required to conduct the Business, and the Intellectual
         Property:-

         (a)      is beneficially owned by or validly licensed to an Obligor,
                  is, to the best knowledge of the Obligors, free from any
                  licenses to third parties and Security Interests, and will not
                  be adversely affected by the transactions contemplated by this
                  Agreement;

         (b)      has not lapsed or been cancelled and all steps have been taken
                  to protect and maintain the Intellectual Property including
                  paying renewal fees where appropriate; and

         (c)      does not, to the best knowledge of any Obligor, infringe any
                  intellectual property rights of any nature of any third party.

12.13.4  ChiRex (Annan) Limited has made appropriate provision for an
         operationally and economically viable source of water supply for the
         needs of the Business currently conducted, or anticipated, at the Annan
         Facility.

12.14    Tax Liabilities

         No claims are being or are reasonably likely to be asserted against it
         with respect to Taxes which would be reasonably likely to have a
         Material Adverse Effect.

12.15    Solvency

12.15.1  As at the Initial Drawdown Date, immediately prior to each Drawdown, it
         will be solvent within the 


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         definition of any law applicable to it which requires as a condition to
         the validity (and/or non-avoidability) of financial obligations
         undertaking by it that it be solvent.

12.15.2  It has not taken any action nor (so far as it is aware having made all
         due enquiry) have any steps been taken or legal proceedings been
         started against it for winding-up, dissolution or re-organisation, the
         enforcement of any Security Interest over its assets or for the
         appointment of a receiver, administrative receiver, or administrator,
         trustee, judicial factor, manager for credits, or similar officer of it
         or of any or all of its assets or any other procedure under which it
         obtains protection from any of its creditors, or any analogous
         proceedings in any relevant jurisdiction.

12.16    Group Structure

         The structure of the ChiRex Group as at the Initial Drawdown Date is as
         set out in Schedule 4.

12.17    Indebtedness

         The Obligors have no Financial Indebtedness as of the date of this
         Agreement other than as set forth in subclause (iii) of the definition
         of Permitted Indebtedness.

12.18    Margin Stock

         Neither it, nor any of its subsidiaries, is engaged principally, or as
         one of its important activities, in the business of extending credit
         for the purpose of purchasing or carrying any Margin Stock and none of
         the proceeds of the facilities made available hereunder will be used,
         directly or indirectly, to purchase or convey any Margin Stock or to
         extend credit to others for the purchasing or conveying of any Margin
         Stock.

12.18.1  Accountants' Report; Industry Report; Business Plan; Operating Budget

         In relation to the Accountants' Report:-

         (a)      all factual information contained in the Accountants' Report
                  was, at the date of the report, true and accurate in all
                  material respects; and


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         (b)      all assumptions and presumptions contained in the Accountants'
                  Report (on the consolidated basis contemplated in the
                  Accountants' Report) attributable to the ChiRex Group were
                  reasonable at the time they were made and in relation to the
                  period in respect of which they were made.

         In relation to the Industry Report:-

         (c)      all factual information contained in the Industry Report was,
                  at the date of the report, true and accurate in all material
                  respects; and

         (d)      all assumptions and presumptions contained in the Industry
                  Report (on the consolidated basis contemplated in the Industry
                  Report) attributable to the ChiRex Group were reasonable at
                  the time they were made and in relation to the period in
                  respect of which they were made.

         In relation to the Business Plan and the Operating Budget:

         (e)      all factual information contained in or utilised for the
                  purpose thereof was, at the date thereof, true and accurate in
                  all material respects and nothing has occurred since the date
                  thereof which renders any factual statement contained therein
                  or so utilised misleading in any material respect;

         (f)      all assumptions and presumptions made for the purpose thereof
                  were fair and reasonable at the time they were made and in
                  relation to the period in respect of which they were made and
                  so far as the ChiRex Group is aware (after having made all due
                  enquiry) nothing has occurred since the date thereof which
                  makes it necessary to change the consolidated forecasts,
                  projections and estimates set out therein in any material
                  respect; and

         (g)      all forecasts, projections and estimates taken on a
                  consolidated basis contained or referred to in the Operating
                  Budget and all assumptions and presumptions upon the basis of
                  which the same were made, at the time they were made were, to
                  its best knowledge, fair and reasonable and, so far as the
                  ChiRex Group is aware (after having made all due enquiry),
                  nothing has occurred since the date thereof which makes it
                  necessary to change any of those forecasts, projections and
                  estimates in any material respect.


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12.19    Environmental Report

         In relation to the Environmental Report, (a) to the best knowledge of
         the Borrower after due inquiry all factual information contained in the
         Environmental Report was, at the date of such report, true and accurate
         in all material respects and nothing has occurred since the date of
         such report which renders any factual statement therein misleading in
         any material respect, and (b) all forecasts, projections and estimates
         contained or referred to in the Environmental Report and all
         assumptions and presumptions upon the basis of which the same were
         made, at the time they were made were fair and reasonable and, so far
         as the Borrower is aware (after having made all due enquiry), nothing
         has occurred since the date thereof which makes it necessary to change
         any of those forecasts, projections and estimates in any material
         respect.

12.20    Environmental Warranties

12.20.1  To the best knowledge of each Obligor, no Environmental Event has
         occurred at any time in relation to any site now or previously owned,
         operated or occupied by the Borrower, any Guarantor or any of their
         respective subsidiaries (or with respect to which any of them could be
         subject to an Environmental Claim) which individually or in the
         aggregate could reasonably be expected to have a Material Adverse
         Effect.

12.20.2  It has obtained and is, and has at all times been, in substantial
         compliance with all Environmental Licenses necessary in connection with
         the ownership and operation of its facilities and business as currently
         owned and operated or if there is or has been any failure to so obtain
         or any non-compliance with such Environmental Licenses such failure or
         non-compliance, individually or in the aggregate could not reasonably
         be expected to have a Material Adverse Effect.

12.20.3  No circumstances exist which could reasonably be expected to prevent or
         interfere with any Obligor or any of their respective subsidiaries
         obtaining or being in substantial compliance with any Environmental
         Licenses in the future so as to give rise to a Material Adverse Effect.


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12.20.4  On the basis of its ongoing reviews which identify and evaluate
         liabilities and costs relating to Environmental Law, it has reasonably
         concluded that the application of any Environmental Law to it or any of
         its subsidiaries could not reasonably be expected to have a Material
         Adverse Effect.

12.20.5  Its operations, and the operations of its subsidiaries, are, and at all
         times have been, in full compliance with all Environmental Law or if
         there is any non-compliance with Environmental Laws, such
         non-compliance could not reasonably be expected to have a Material
         Adverse Effect. No circumstances exist which currently are known or
         ought reasonably to be known by it which may reasonably be expected to
         prevent or interfere with any Obligor or any of their respective
         subsidiaries being in full compliance with any Environmental Laws in
         the future so as to give rise to a Material Adverse Effect.

12.21    Labour Law and Employee Benefit Plans

         It has complied with all applicable labour and social security laws and
         instituted all employee benefit plans legally necessary; these plans in
         place are in full force and effect and each such plan is fully funded
         to meet its expected obligations as they come due except for such
         failure to fund, the liability as to which is not reasonably likely to
         have a Material Adverse Effect.

12.22    U.S. Employee Benefit Plans.

         (a)      As at the date of this Agreement no US Obligor has a
                  "multiemployer plan" (as defined in the definition of Employee
                  Benefit Plan) and no Employee Benefit Plan of any US Obligor
                  is subject to Title IV of ERISA.

         (b)      Each Employee Benefit Plan is in compliance in form and
                  operation and in all other material respects with the
                  applicable provisions of ERISA, the Code and any other
                  applicable Federal or U.S. state law, and no event or
                  condition has occurred or exists concerning such Employee
                  Benefit Plan which any US Obligor or any ERISA Affiliate
                  thereof would be under an obligation to report to the Agent in
                  accordance with Clause 13.3.8(e).

12.23    U.K. Employee Benefit Plans.


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         (a)      No agreement or arrangement (other than the Scheme) exists for
                  the provision by any Obligor of any relevant benefits (as
                  defined in Section 612 of the ICTA) for any person or (without
                  limitation to the foregoing) superannuation benefits for
                  employees.

         (b)      The last actuarial valuation of the Scheme disclosed that the
                  aggregate value of the assets of the Scheme at the date of the
                  valuation was equal to or greater than the aggregate value of
                  the liabilities of the Scheme on an on-going basis calculated
                  in accordance with the actuarial methods and assumptions used
                  in the valuation. So far as the Obligors are aware, no event
                  has occurred since the valuation that would have materially
                  adversely affected the funding position of the Scheme.

         (c)      Except that no action has been taken under the Scheme to
                  eliminate discriminatory treatment as between men and women
                  which is attributable to the provision of guaranteed minimum
                  pensions (within the meaning of the Pension Schemes Act 1993),
                  the applicable Obligors have complied in all material respects
                  with their respective obligations under the Scheme in relation
                  to past and present employees and officers of such Obligors
                  and all material amounts due to be paid to the Scheme from
                  such Obligors have been paid.

         (d)      No undertaking or assurance has been given to any member of
                  the Scheme as to continuance, introduction, increase or
                  improvement of any benefits under the Scheme.

         (e)      To the best knowledge of the Obligors, there are not in
                  respect of the Scheme any claims or actions pending or
                  threatened involving any Obligor or the trustees of the Scheme
                  (other than routine claims for benefits).

         (f)      No Obligor is providing, or, upon the consummation of the Sale
                  and Purchase Agreement, will be obligated to provide, material
                  ex gratia pension or other similar payments for any former
                  employee.


         (g)      No company other than the applicable Obligor participates or
                  has participated in the Scheme.

12.24    Governmental Regulation


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          It is not subject to regulation under the Public Utility Holding
          Company Act of 1935, the Federal Power Act, the Interstate Commerce
          Act or the Investment Company Act of 1940 or under any other federal
          or state statute or regulation which may limit its ability to incur
          Financial Indebtedness or which may otherwise render all or any
          portion of the obligations under the Finance Documents unenforceable.

13.       UNDERTAKINGS

13.1      Duration

          Each Obligor undertakes to each of the Finance Parties in the terms of
          the provisions of Clauses 13.2 to 13.4 (inclusive), and ChiRex Inc.
          undertakes to each of the Finance Parties in terms of the provisions
          of Clause 13.5, all such undertakings to continue until the
          liabilities and obligations under each of the Finance Documents have
          been finally discharged and no Finance Party has any obligation to
          lend hereunder, unless in any case the Agent (acting on the
          instructions of the Majority Lenders) agrees otherwise. All
          undertakings set forth in this Clause 13 are cumulative such that, if
          more than one set of such undertakings are given by an Obligor, such
          Obligor shall be bound by the aggregate of all restrictions set forth
          in the undertakings given by it.

13.2      General Undertakings

13.2.1    Use of Proceeds

          It will procure that the proceeds of Advances be used only for the
          purposes specified in Clause 2.2.

3.2.2     Authorisations and Consents

          It will, and will procure that each of its subsidiaries will, obtain
          and promptly renew from time to time and maintain in full force and
          effect all such authorisations, approvals, consents, licenses and
          exemptions, and promptly make and renew from time to time all such
          filings and registrations, as may be required under any applicable law
          or regulation (i) to enable it to perform its obligations under each
          of the Finance Documents and (ii) for the validity and enforceability
          thereof, subject to the Reservations.

13.2.3    Change of Business


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          It will not, and will procure that each of its subsidiaries will not,
          engage in any material business other than the Business or any
          business reasonably incidental thereto.

13.2.4    Maintenance of Status and Authorisations, Title to Assets

          It will, and will procure that each of its subsidiaries will:-

          (a)       do all such things as are necessary to maintain their
                    respective legal existences, except that any two or more
                    subsidiaries of an Obligor may consolidate or merge with one
                    another, in each case in accordance with Clause 13.2.9;

          (b)       ensure that it and each of them has the right and is duly
                    qualified to conduct their respective businesses as
                    conducted in all applicable jurisdictions, and obtain and
                    maintain all licenses, consents, authorisations, franchises,
                    Intellectual Property and other rights necessary for the
                    preservation and operation of such businesses in all
                    material respects, except to the extent that the absence of
                    any such right or qualification, or the non-existence or
                    non-maintenance of such licenses, consents, authorisations,
                    franchises, property or rights would not be reasonably
                    likely to have a Material Adverse Effect; and

          (c)       comply in all material respects with all laws, regulations,
                    judgements, decrees, orders, licenses, permits or consents
                    binding upon it, except where non-compliance would not be
                    reasonably likely to have a Material Adverse Effect.

13.2.5    Arm's Length Transactions

          It will not enter into, and will procure that each of its subsidiaries
          does not enter into, any arrangement or transaction other than (i) on
          an arm's length basis and for at least market value, or (ii) on terms
          that in every respect are equal to or more advantageous to such
          Obligor.

13.2.6    Insurances

          It will:-


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          (a)       maintain and will procure that each of its subsidiaries
                    maintains in full force and effect adequate insurance
                    (including, without limitation, employer's and public
                    liability insurance and business interruption/loss of
                    profits insurance) in relation to its and their respective
                    assets and businesses against all such risks as are normally
                    insured against by other companies (whose practice is not to
                    self-insure except in connection with reasonable excesses)
                    owning or possessing similar assets or carrying on similar
                    businesses in an amount, to the extent reasonably possible,
                    equal to the full replacement cost of such assets (after
                    allowing for any decrease in value of such assets as a
                    result of normal wear and tear in the case of plant and
                    machinery and related assets), in respect of its or their
                    respective businesses, except where its failure to do so
                    would not be reasonably likely to have a Material Adverse
                    Effect;

          (b)       procure that the interest of the Security Agent is noted on
                    all policies of such insurance (or at the option of the
                    Security Agent, acting reasonably, and where the relevant
                    insurer agrees, that such policies are issued in the joint
                    names of the Security Agent and the relevant Obligor); and

          (c)       if so requested by the Agent, supply copies of all such
                    policies, and receipts for all premiums and other payments
                    necessary for effecting and keeping such policies.

13.2.7    Taxes

          It will pay within any permitted period, and will procure that each of
          its subsidiaries pays within any permitted period, all material Taxes
          imposed upon it or any of them or any of its or their assets, income
          or profits or any transactions undertaken or entered into by it or any
          of them (other than such Taxes as are being contested in good faith by
          appropriate proceedings, pending determination of which payment may
          lawfully be withheld without penalty, in respect of which Taxes there
          shall be set aside adequate reserves in accordance with the applicable
          Approved Accounting Principles).

13.2.8    Disposals

          It will not, and will procure that its subsidiaries will not (whether
          by a single transaction or a number of related or unrelated
          transactions and whether at the same


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          time or over a period of time) sell, transfer or otherwise dispose of
          any of its assets (including shares of the capital stock of any other
          person, or if such person is not an incorporated entity, other
          ownership interests therein, and the coverage of this undertaking is
          to be deemed to include any transaction the effect of which would be
          to reduce the percentage of any class of shares or interests in any
          person held directly or indirectly by such Obligor) or all or any part
          of its undertakings, assets or revenues or any interest therein, other
          than:-

          (a)       disposals of assets on an arm's length basis in the ordinary
                    course of trading;

          (b)       payment of cash in respect of a transaction not otherwise
                    prohibited by this Agreement, and exchange of cash
                    equivalents for cash;

          (c)       the exchange, or replacement within three months, of assets
                    for or with other assets required for its trading activities
                    of similar or greater value than the assets disposed of or
                    replaced, on arm's length commercial terms;

          (d)       disposals of assets which are no longer required for the
                    purposes of its business at a price not significantly less
                    than the market value of those assets less, if the assets
                    would otherwise be liquidated, the costs of the liquidation;
                    or

          (e)       disposals, other than disposals of shares or ownership
                    interests in ChiRex America Inc. or the Borrower, not
                    falling within any other paragraph of this Clause 13.2.8
                    whose consideration does not exceed GBP 5,000,000 (or its
                    equivalent) in any one Accounting Reference Period and GBP
                    15,000,000 (or its equivalent) when aggregated with all
                    other such disposals made by the Obligors and each of their
                    respective subsidiaries following the date of this
                    Agreement.

13.2.9    Merger, Consolidation, Etc.

          It will not, and will procure that its subsidiaries do not, merge or
          consolidate with any other person (whether by winding-up, dissolution
          or other means) except that:-

          (a)       two or more Tier I Guarantors may consolidate or merge with
                    one another or an Obligor which is not a


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                    Tier I Guarantor may merge into an Obligor which is a Tier I
                    Obligor, and

          (b)       any subsidiary of an Obligor may merge into such Obligor,

          provided in that the Agent shall have received legal opinions in
          respect of the relevant merger or consolidation in form and substance
          reasonably satisfactory to the Agent, which legal opinions shall, in
          any event, confirm that none of the material rights of any Finance
          Party or the material obligations and liabilities to any Finance Party
          of any Obligor will, after such merger or consolidation, cease to be
          in full force and effect and that the person surviving or resulting
          from such merger or consolidation is bound under the Finance Documents
          after giving effect to such merger or consolidation to the same extent
          as the other person or persons party to such transaction were bound
          immediately prior thereto.

13.2.10   Negative Pledge; Absence of Other Negative Pledges

          (a)       It will not, and will procure that its subsidiaries will
                    not, create or have outstanding any Security Interest on or
                    over its respective assets, other than Permitted Security
                    Interests.

          (b)       It will not, and will procure that none of its subsidiaries
                    will, covenant for the benefit of any person other than the
                    Lenders pursuant to the Finance Documents, to refrain from
                    granting for the purpose of securing Financial Indebtedness,
                    Security Interests on all or any portion of its or their
                    assets or properties, except (i) in respect of assets
                    subject to Permitted Security Interests in favour solely of
                    the holder of the relevant Security Interest and (ii) any
                    such covenants in existence on the date hereof pursuant to
                    any of the Continuing Indebtedness provided that the
                    principal amount of such Continuing Indebtedness shall not
                    be increased after the date hereof.

13.2.11   Indebtedness

          It will not, and will procure that its subsidiaries will not, incur or
          permit to exist any Financial Indebtedness other than Permitted
          Indebtedness.

13.2.12   Loans, Etc.


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          It will not, and will procure that its subsidiaries will not, make or
          permit to be outstanding any loans or grant any credit to any person
          or make any other similar arrangement other than:-

(i)       loans to directors or employees which, together with all such loans
          made by the Borrower and its subsidiaries, do not exceed a maximum
          aggregate amount of GBP 1,000,000 (or its equivalent) outstanding at
          any time;

(ii)      trade credit granted in the ordinary course of its trading business,

(iii)     loans to all material terms of which the Agent (acting upon the
          instructions of the Majority Lenders) has consented; and

(iv)      loans or credits granted by one of the Borrower's subsidiaries to the
          Borrower or another of the Borrower's subsidiaries.

13.2.13   Acquisitions of Subsidiaries or Businesses

          It will not, and will procure that its subsidiaries will not (i)
          acquire any subsidiary which is not its subsidiary as at the date of
          this Agreement, (ii) acquire any business, or (iii) enter into any
          agreement under which it may be or become bound to acquire any such
          subsidiary or business other than:-

          (a)       subsidiaries or businesses acquired exclusively with the
                    proceeds of one or more sales of equity securities or rights
                    in relation thereto, where (i) the subsidiary or business to
                    be acquired is such that it would not result in the untruth
                    or inaccuracy of any representation or warranty set forth
                    herein, the violation of any covenant set forth herein, or
                    the occurrence of any Potential Event of Default or Event of
                    Default, as demonstrated in each case to the reasonable
                    satisfaction of the Agent, (ii) if on a pro forma basis (as
                    demonstrated to the reasonable satisfaction of the Agent),
                    the proposed acquisition would result in there being a
                    Material Subsidiary which is not an Obligor, the acquiror
                    shall simultaneously with the acquisition cause compliance
                    by the acquired business or acquired subsidiary with Clause
                    13.2.22, and (iii) if the business or subsidiary proposed to
                    be acquired has any interest in real property which may
                    subject such business or subsidiary or any other member of
                    the ChiRex Group


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                    to liability under any Environmental Law, the acquiror shall
                    provide to the Agent a report of the type described in
                    Clause 13.2.18(g) in all respects satisfactory to the Agent
                    no fewer than 20 days prior to the date of the proposed
                    acquisition; and

          (b)       subsidiaries or businesses acquired in whole or in part with
                    the proceeds of Financial Indebtedness (including any direct
                    or indirect usage of the Tranche B Facility), where (i) the
                    acquisition satisfies the requirements of the preceding
                    Clause 13.2.13(a), and (ii) the Agent has received evidence
                    to its reasonable satisfaction that the proposed acquisition
                    will not result in the ChiRex Group having available to it
                    at any time insufficient cash or liquid assets to enable it
                    to meet all of the payment obligations under this Agreement
                    as well as all other material liabilities as they are then
                    anticipated to fall due.

13.2.14   Restriction on Redemption and Acquisition of Own Shares

          It will not, and will procure that none of its subsidiaries will,
          directly or indirectly redeem, purchase, retire or otherwise acquire
          for consideration any shares, warrants or other equity or equity
          related securities issued by it or set apart any sum for any such
          purpose or otherwise reduce its capital without the consent of the
          Agent (acting on the instructions of the Majority Lenders), except to
          the extent that any sums paid or set apart by ChiRex Inc. in respect
          of the redemption, purchase, retirement or acquisition of its shares,
          when added to any other Restricted Payments, do not exceed in
          aggregate the Available Amount.

13.2.15   Blockage of Payments, Etc.

          It is not, and will procure that none of its subsidiaries is, a party
          to any contractual or similar arrangement pursuant to which any such
          subsidiary is prohibited from making any loan, payment of dividends,
          distributions of income or other amounts, or transferring any
          properties or assets, to it, or any condition or requirement is
          imposed on any such payment or transfer except, in the case of
          prohibitions on transfers of properties or assets, customary
          provisions restricting subletting or assignment of any lease governing
          a leasehold interest of it or one of its subsidiaries.

13.2.16   Restriction on Payment of Dividends, Etc.


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          It will not declare or pay, directly or indirectly, any dividends or
          make any other distribution, or other amounts whether in cash or
          otherwise, on any of its ordinary or other shares except to the extent
          that dividends paid by ChiRex Inc., when added to any other Restricted
          Payments, do not exceed in aggregate the Available Amount.

13.2.17   Material Agreements

          The relevant Obligor will at its own cost and expense take all
          reasonable steps to preserve and enforce available rights and remedies
          in respect of the Material Agreements or any breach thereof, maintain
          in full force and effect (subject to rights of termination exercisable
          by the other party or parties thereto not arising from the relevant
          Obligor's actions or omissions) and during their term comply with the
          terms of the Material Agreements in all material respects, and not
          agree to any waiver of any material term of or to any material
          amendment or variation of the terms of the Material Agreements, except
          to the extent that the failure to perform or observe any of the
          undertakings set forth in this Clause 13.2.17 is not reasonably likely
          to have a Material Adverse Effect.

13.2.18   Environmental Obligations

          (a)       It will, and will procure that each of its subsidiaries
                    will, (i) comply with the terms of all Environmental
                    Licenses and Environmental Laws applicable to it or any of
                    its subsidiaries, (ii) promptly pay or cause to be paid all
                    costs and expenses incurred in such compliance and (iii)
                    keep or cause to be kept all real property now or hereafter
                    owned or operated by it or any of its subsidiaries free and
                    clear of any Security Interests imposed pursuant to such
                    Environmental Laws for such period as such real property is
                    owned or operated by it or any of its subsidiaries, except
                    for such non-compliances, failures to pay or Security
                    Interests which individually or in the aggregate could not
                    reasonably be expected to have a Material Adverse Effect.

          (b)       It shall promptly take, and shall cause each of its
                    subsidiaries promptly to take, any and all investigation,
                    study, sampling, testing, abatement, clean up, removal,
                    remediation, or other appropriate response action necessary
                    to remove, remediate,


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                    clean up, or abate any Environmental Contamination that is
                    in violation of any Environmental Laws or that presents a
                    material risk of giving rise to an Environmental Claim where
                    the failure to do is reasonably likely to have a Material
                    Adverse Effect. In the event it or any of its subsidiaries
                    undertakes any such action with respect to any Dangerous
                    Substances on, under or about any real property owned or
                    operated by any of them, it or such subsidiary shall conduct
                    and complete such action in compliance with all applicable
                    Environmental Laws, and in accordance with the policies,
                    orders and directives of all Governmental Authorities except
                    when, and only to the extent that, its or such subsidiary's
                    liability for such presence, storage, use, disposal,
                    transportation or discharge of any Dangerous Substances is
                    being contested in good faith by it or such subsidiary.

          (c)       It shall promptly take, and shall cause each of its
                    subsidiaries promptly to take, any and all action necessary
                    to cure any violation of applicable Environmental Laws by
                    such Obligor or its Subsidiaries that could reasonably be
                    expected to have, individually or in the aggregate, a
                    Material Adverse Effect.

          (d)       It will not, and will procure that each of its subsidiaries
                    will not, generate, use, treat, store, release or dispose
                    of, or permit the generation, use, treatment, storage,
                    release or disposal of Dangerous Substances on any real
                    property now or hereafter owned or operated by it or any of
                    its subsidiaries, or transport or permit the transportation
                    of Dangerous Substances to or from any such real property
                    except for Dangerous Substances used or stored at, or
                    transported from, any such real properties in compliance
                    with all applicable Environmental Laws and used in
                    connection with the operation, use and maintenance of any
                    such real property, except such non-compliances as could not
                    reasonably be expected to have a Material Adverse Effect.

          (e)       If: (i) an Event of Default has occurred and is continuing;
                    (ii) the Lenders receive notice under Clauses 13.2.18(f) or
                    13.2.18(g) for any event for which notice is required to be
                    delivered for any such real property; or (iii) the Agent or
                    the Majority Lenders reasonably believe that there was a
                    breach of any representation, warranty or covenant


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                    contained in Clause 12.20, 13.2.18(a) or 13.2.18(d); then,
                    at the written request of the Agent or the Majority Lenders,
                    which request shall specify in reasonable detail the basis
                    therefor, at any time and from time to time, it will
                    provide, at the Borrower's sole cost and expense, an
                    environmental site assessment report and compliance audit
                    concerning any real property in form and substance
                    satisfactory to the Agent, prepared by an environmental
                    consulting firm approved by the Agent addressing the matters
                    in sub-clause (i), (ii) or (iii) above of this Clause
                    13.2.18(e) which gives rise to such request and estimating
                    the range of the potential costs of any removal, remedial or
                    other corrective action in connection with any such matter.
                    If the Borrower fails to provide the same within 90 days
                    after such request was made, the Agent may order the same,
                    and the Obligors shall grant and hereby grant to each of the
                    Agent and the Lenders and their agents access to such real
                    property and specifically grant the Agent and the Lenders an
                    irrevocable non-exclusive license, subject to the rights of
                    tenants, to undertake such an assessment all at the expense
                    of the Borrower (including, without limitation, taking
                    samples of soil, groundwater and suspected asbestos
                    containing materials). Any such investigation of any real
                    property shall be conducted, unless otherwise agreed to by
                    Borrower and Agent, during normal business hours and, to the
                    extent reasonably practicable, shall be conducted so as not
                    to interfere with the ongoing operations at any such real
                    property or to cause any damage or loss to any property at
                    such real property. Borrower and Agent hereby acknowledge
                    and agree that any report of any investigation conducted at
                    the request of Agent pursuant to this Clause 13.2.19(e) will
                    be obtained and shall be used by Agent and Lenders for the
                    purposes of Lenders' internal credit decisions, to monitor
                    and police the Facilities and to protect Lenders' security
                    interests, if any, created by the Finance Documents. Agent
                    agrees to deliver a copy of any such report to Borrower with
                    the understanding that Borrower acknowledges and agrees that
                    (i) it will indemnify and hold harmless Agent and each
                    Lender from any costs, losses or liabilities relating to
                    Borrower's use of or reliance on such report, (ii) neither
                    Agent nor any Lender makes any representation or warranty
                    with respect to such report, and (iii) by delivering such
                    report to Borrower neither Agent nor any Lender is


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                    requiring or recommending the implementation of any
                    suggestions or recommendations contained in such report.

          (f)       Promptly upon, and in any event within five Business Days
                    after, an officer or director of any Obligor obtaining
                    knowledge thereof, written notice of any of the following
                    matters (including all reasonably related claims or
                    liabilities) which could reasonably be expected to result in
                    costs to any Obligor in excess of GBP 2,500,000 shall be
                    delivered to the Lenders:-

(i)       any pending or threatened Environmental Claim against any Obligor
          (including any such claim arising out of the ownership or operation by
          an Obligor, or any predecessor-in-interest thereto, of any real
          property then no longer owned by such Obligor) or any real property
          then owned or operated by an Obligor and any pending or threatened
          suspension, revocation or material modification of any Environmental
          License applicable to such Obligor (including any threatened closure
          or shutdown of all or any part of a facility owned or operated by such
          Obligor);

(ii)      any condition or occurrence on or arising from any real property owned
          or operated by any Obligor (or with respect to which any Obligor has
          liability) that (x) results in material noncompliance by an Obligor
          with any applicable Environmental Law or (y) could reasonably be
          expected to form the basis of an Environmental Claim against an
          Obligor, or any predecessor-in-interest thereto, (including any such
          claim arising out of the ownership or operation by an Obligor of any
          real property then no longer owned by such Obligor) or any real
          property then owned by an Obligor;

(iii)     any condition or occurrence on any real property owned or operated by
          any Obligor that could reasonably be expected to cause such real
          property to be subject to any restrictions on the ownership,
          occupancy, use or transferability by such Obligor of such real
          property under any Environmental Law;

(iv)      the taking of any removal or remedial action in response to the actual
          or alleged presence of any Dangerous Substances on any real property
          owned or operated by an Obligor, or any predecessor-in-interest
          thereto, as required by any Environmental Law or any Governmental
          Authority; and


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(v)       any change or addition to any applicable Environmental Law the effect
          of which change or addition is reasonably likely to have a Material
          Adverse Effect.

                    All such notices shall describe in reasonable detail the
                    nature of the claim, investigation, condition, occurrence or
                    removal or remedial action and the relevant Obligor's
                    response thereto. In addition, the relevant Obligor will
                    provide the Lenders with copies of such detailed reports of
                    any Environmental Claim as may reasonably be requested by
                    the Majority Lenders. In addition, promptly upon receiving
                    written notice of the entry of any real property (or any
                    property with respect to which it or any of its subsidiaries
                    has liability or potential liability) on any register or
                    database maintained by any Governmental Authority or like
                    authority for those properties deemed contaminated with
                    Dangerous Substances including, without limitation, a "black
                    spots" list, inform the Agent of the entry where the entry
                    has or could reasonably be expected to have a Material
                    Adverse Effect.

          (g)       It will, and will procure that each of its subsidiaries
                    will, undertake a suitable site assessment of the
                    Environmental status of any material real property (or any
                    material interest therein) or any company in which it
                    intends or they intend to acquire a majority interest (which
                    assessments shall include, but not be limited to, a written
                    environmental site assessment prepared by a reputable
                    environmental consultant for real property or interests
                    therein acquired or held by any company to be acquired),
                    provided it is so permitted by the then owner of such real
                    property, and will notify the Agent of the results of such
                    assessment.

13.2.19   Intellectual Property

          It will:-

          (a)       make such registrations and pay such fees, registration
                    Taxes and similar amounts as are necessary to keep all
                    Intellectual Property rights which are material to the
                    business of any member of the ChiRex Group in force and to
                    record its interest in those Intellectual Property rights;
                    and

          (b)       take such steps as are necessary and commercially reasonable
                    (including, without limitation, the institution of
                    appropriate legal proceedings) to


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                    prevent third parties from infringing those Intellectual
                    Property rights referred to in paragraph (a) above and
                    (without prejudice to paragraph (a) above) take such other
                    steps as are reasonably practicable to maintain and preserve
                    its interest in those rights.

13.2.20   Investments

          It will not, and will procure that its subsidiaries will not, own any
          interest in any share, equity related investment or investment
          security other than Permitted Investments.

13.2.21   Financial Indebtedness within the ChiRex Group

          It will not, and will procure that its subsidiaries will not, permit
          any Financial Indebtedness or other obligation owed by it to another
          Obligor or to it by another Obligor, to be either (i) contractually
          subordinated to any other obligations, or (ii) evidenced by a note or
          other similar instrument, unless that note or instrument is pledged to
          the Security Agent on behalf of the Lenders in a manner satisfactory
          in all respects to the Security Agent.

13.2.22   Additional Guarantors

          Each Obligor will procure that each of its subsidiaries which either
          after the date of this Agreement becomes a Material Subsidiary (an
          "Existing Material Subsidiary") or is a person to be acquired pursuant
          to Clause 13.2.13 which would be a Material Subsidiary after giving
          effect to such acquisition (an "Acquired Material Subsidiary")
          executes and delivers, except to the extent that (i) such execution
          and delivery is prohibited by law or (ii) it would, in the reasonable
          opinion of the Agent, create an unreasonable risk of liability for the
          directors of such Material Subsidiary after taking into account the
          costs of the contingent liability to the Material Subsidiary
          attributable to the guaranteeing of obligations under the Finance
          Documents versus the benefits to be derived therefrom by such Material
          Subsidiary, in the case of an Existing Material Subsidiary, within 90
          days of availability to the Borrower of information demonstrating that
          such subsidiary has become a Material Subsidiary and, in the case of
          an Acquired Material Subsidiary, substantially contemporaneously with
          the consummation of its acquisition (and in any event within 30 days
          thereafter), to the Agent a Deed of Accession and the


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          documents described in the following sub-clauses (i), (ii) and (iii)
          relevant to it:

(i)       a copy, certified as of the date of the Deed of Accession as true and
          complete by a duly authorised representative of such Material
          Subsidiary of:

                    (A)       the constitutional documents of such Material
                              Subsidiary, including evidence of due
                              incorporation;

                    (B)       board (or other appropriate governing body)
                              resolutions of such Material Subsidiary (A)
                              approving the transactions and the matters
                              contemplated by each of the Finance Documents, and
                              (B) authorising a specified person or persons to
                              (x) execute on its behalf each of the Finance
                              Documents to which it is a party, and (y) give all
                              notices, requests, instructions, certificates and
                              other documents for that Material Subsidiary in
                              connection with each of the Finance Documents to
                              which it is a party;

                    (C)       all other corporate, trust or other applicable
                              authorisations and actions required of it
                              (including without limitation any resolutions of
                              shareholders or approvals of beneficiaries) to
                              enable it to enter into, execute and perform those
                              of the Finance Documents to which it is, or is to
                              be, a party;

                    (D)       specimen signatures of the signatories authorised
                              by such Material Subsidiary in the board (or other
                              appropriate governing body) resolutions described
                              in Clause 13.2.22(i)(B) to sign Financing
                              Documents to which it is or is to be a party; and

                    (E)       all other resolutions, powers, declarations,
                              approvals, consents and licenses (corporate,
                              official or otherwise) necessary or appropriate
                              for the entry into and performance by such
                              Material Subsidiary of the Finance Documents to
                              which it is or is to be a party, and for the
                              enforceability and validity thereof;


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(ii)      a legal opinion properly addressed to the Agent and Lenders from
          reputable counsel acceptable to the Agent in the jurisdiction in which
          such Material Subsidiary is organised or incorporated, who may be
          counsel to ChiRex Inc.; and

(iii)     such other documents as the Agent may reasonably request.

13.2.23   No Payment of Management Fees

          No Obligor will pay to any member of the ChiRex Group which is not an
          Obligor management fees, royalty fees or otherwise except in respect
          of services actually provided on commercially reasonable terms.

13.3      Information and Accounting Undertakings

13.3.1    Events of Default

          ChiRex Inc. will notify the Agent of the occurrence of any Event of
          Default or Potential Event of Default immediately upon becoming aware
          of it and will from time to time on request deliver to the Agent a
          certificate confirming that no Event of Default or Potential Event of
          Default has occurred or setting out details of any Event of Default or
          Potential Event of Default and the action taken or proposed to be
          taken to remedy it.

13.3.2    Books of Account

          Each Obligor will, and will procure that each of its respective
          subsidiaries will, keep proper books of account and will prepare
          management accounts in the usual form and will permit the Agent or any
          authorised representative of the Agent upon reasonable notice to visit
          them and inspect the same at the place where they are maintained and
          to interview such officers and employees of the Borrower as the Agent
          may reasonably require, provided that such visits and interviews may
          not occur more frequently than once a year unless an Event of Default
          has occurred.

13.3.3    Appointment of Auditors

          No Obligor will at any time appoint or continue to employ any auditors
          other than the Auditors or other auditors of international repute
          approved by the Agent, provided that nothing in this Clause 13.3.3
          shall limit or otherwise affect the appointment of statutory auditors.

13.3.4    Financial Statements and Operating Budget


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          The Obligors will deliver, or cause to be delivered, to the Agent in
          form and substance acceptable to the Agent for distribution to the
          Lenders sufficient copies for each of the Lenders of the following:-

          (a)       as soon as available and in any event within the period
                    required to be delivered to the SEC, the Form 10-K of ChiRex
                    Inc. which incorporates the consolidated financial
                    statements of ChiRex Inc. and its subsidiaries, audited by
                    the Auditors as at the end of and for that financial year;

          (b)       as soon as available and in any event within the period
                    required to be delivered to the SEC, the Form 10-Q of ChiRex
                    Inc. which incorporates the unaudited consolidated financial
                    statements of ChiRex Inc. and its subsidiaries and the
                    relevant consolidating adjustments as at the end of, and
                    for, the relevant Accounting Quarter;

          (c)       as soon as available and in any event within 30 days after
                    the end of each fiscal month for the first eleven months of
                    each Accounting Reference Period, consolidated monthly
                    management accounts for each of (i) the ChiRex Group, and
                    (ii) the Borrower (setting forth separately income and
                    expenses of ChiRex (Annan) Limited and ChiRex (Dudley)
                    Limited) each as at the end of such month including, without
                    limitation, a consolidation adjustment column;

          (d)       not more than 30 days after the beginning of each successive
                    Accounting Reference Period, the Operating Budget applicable
                    to such Accounting Reference Period; and

          (e)       within 120 days after the end of each Accounting Reference
                    Period, a report of ChiRex Inc. describing in reasonable
                    detail each of the respective elements of the unconsolidated
                    Cashflow of each Obligor demonstrating the calculations made
                    in order to determine the Cashflow in each such case and, to
                    the extent practicable, reconciling the figures set forth
                    therein to the relevant audited figures;

          provided, that the financial statements provided pursuant to
          Sub-clauses 13.3.4(a), (b) and (c) shall include, without limitation,
          in respect of each Accounting Quarter or Accounting Reference Period,
          as the case may be, a statement of consolidated profit and loss, a
          consolidated balance sheet, a consolidated cash flow statement,


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          together with a comparison of all such information with the
          information, if any such consolidated information is available, for
          the corresponding period in the preceding financial year (or part
          thereof following the date hereof), and the financial statements
          provided pursuant to Sub-clauses 13.3.4(c) to include a comparison
          with the relevant projections, estimates or forecasts in the relevant
          Operating Budget.

13.3.5    Financial Covenant and Other Compliance Certificates

          Each of the financial statements delivered under Subclauses 13.3.4(a),
          (b) and (c) shall be accompanied by a certificate signed by the chief
          financial officer of ChiRex Inc. and (in the case of financial
          statements delivered pursuant to Sub-clause 13.3.4(a) approved by a
          the Board of Directors of ChiRex Inc., certifying whether or not the
          Obligors are in compliance with each of the covenants contained in
          Clause 13.4 (such certificate to contain detailed calculations
          reasonably acceptable to the Agent demonstrating such determination),
          confirming that at the date of such financial statement, no Event of
          Default or Potential Event of Default has occurred, or if one has
          occurred, a description thereof and the action taken or proposed to be
          taken to remedy it and, in the case of the annual financial
          statements, (i) listing each Material Subsidiary as at the date of
          such annual financial statements, and (ii) accompanied by a
          certificate from the Auditors (in such form and with such content as
          the Agent may reasonably require) demonstrating whether or not the
          Obligors are in compliance with the covenants contained in Clause
          13.4.

13.3.6    Accounting Reference Period/Accounting Quarter

          No alteration may be made to its Accounting Reference Period or
          Accounting Quarters without the prior written consent of the Agent
          (which consent shall not be unreasonably withheld). The Agent may
          require such changes in the financial covenants contained in this
          Agreement as will fairly reflect any such change.

3.3.7     Auditors' Investigations

          [*** Clause Reserved ***]

13.3.8    Other Information

          Each Obligor (or each US Obligor, as applicable) will promptly deliver
          to the Agent for distribution to the Lenders:-


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          (a)       details of any litigation, arbitration or administrative
                    proceedings relating to such Obligor which is reasonably
                    likely to give rise to a Material Adverse Effect;

          (b)       at the same time as sent to any of its financial creditors,
                    any other material document or information sent to such
                    creditors;

          (c)       such other information relating to its financial condition
                    or operations (including sales and details in relation to
                    its debtors), or those of any other Obligor as the Agent (or
                    any other Lender through the Agent) may from time to time
                    reasonably request;

          (d)       details of any occurrence or circumstance which will
                    materially adversely affect the ability of any Obligor to
                    perform any of its payment obligations under any of the
                    Finance Documents;

          (e)       promptly upon becoming aware of any event or circumstance
                    pertaining to an Employee Benefit Plan which is reasonably
                    likely to give rise to a Material Adverse Effect, a written
                    notice specifying the nature thereof, what action the
                    relevant US Obligor or any of its ERISA Affiliates has
                    taken, is taking or proposes to take with respect thereto
                    and, when known, any action taken or threatened by the
                    United States Internal Revenue Service, the United States
                    Department of Labor or the PBGC with respect thereto; and

          (f)       a copy of any notice or other writing received or issued by
                    any Obligor in connection with the possible termination,
                    revocation or modification of the terms of any license,
                    consent or authorisation necessary for the carrying on of
                    the Business, or the termination, waiver, amendment or
                    variance of any Material Agreement.

13.3.9    Other Investigations

          It will, and will procure that its subsidiaries will, at any time
          during the occurrence of a Potential Event of Default or an Event of
          Default, permit the Agent and such person or persons as the Agent
          shall nominate at all reasonable times during normal business hours
          and on not less than 24 hours' written notice to enter into and upon
          the principal premises from which the relevant Obligor's or
          subsidiary's business is being conducted to view the state and
          condition of such premises.

13.3.10   Approved Accounting Principles


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          All audited financial statements or accounts of the Obligors delivered
          or to be delivered to the Agent under this Agreement shall be prepared
          in accordance with the relevant Approved Accounting Principles. If,
          (i) as a result of a change in law or other change in Approved
          Accounting Principles such statements or accounts are required to be
          prepared on a different basis, or (ii) any change in Approved
          Accounting Principles would result in any material change in the
          manner in which any item relevant to the covenants in Clause 13.4
          (Financial Covenants) is accounted for or reported by any Obligor, or
          (iii) any Obligor shall propose to change its Approved Accounting
          Principles from those specified in the definitions herein:-

          (a)       the relevant Obligor shall promptly so advise the Agent, and
                    shall deliver to the Agent (with sufficient copies for the
                    Lenders) the Operating Budget for the then current
                    Accounting Reference Period and the financial statements
                    required to be delivered under Clauses 13.3.4(a) and (b)
                    during the prior twelve month period, in each case, giving
                    effect to the relevant changes;

          (b)       on request of the Agent (which request shall be deemed made
                    in the case of a proposal to change any of the Approved
                    Accounting Principles from those specified in the
                    definitions herein), the Obligors and the Agent (on behalf
                    of the Lenders) shall negotiate in good faith with a view to
                    agreeing such amendments to Clauses 13.4 and/or the
                    definitions of any or all of the terms used therein as are
                    necessary as a result of such change in law or in generally
                    accepted accounting principles (or other change) to give the
                    Lenders comparable protection to that contemplated at the
                    date of this Agreement;

          (c)       if amendments satisfactory to the Lenders are agreed by the
                    Obligors and the Agent in writing within 30 days of such
                    notifications to the Agent, those amendments shall take
                    effect in accordance with the terms of that agreement; and

          (d)       if such amendments are not so agreed within 30 days, within
                    15 days after the end of that 30 day period, the relevant
                    Obligor shall either:-

(i)       deliver to the Agent, in reasonable detail and in a form satisfactory
          to the Agent, details of all such adjustments as need to be made to
          the relevant financial statements in order to bring them into line
          with Approved


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          Accounting Principles or, as the case may be, to eliminate the effect
          of the relevant change; or

(ii)      ensure that the relevant financial statements are prepared in
          accordance with the relevant Approved Accounting Principles subject,
          as the case may be, to eliminating the effect of the relevant change.

13.3.11   Annual Meeting with Banks

          At the request of the Agent, the Obligors shall within 120 days after
          the close of each Accounting Reference Period, hold a meeting at a
          time and place selected by the Obligors and reasonably acceptable to
          the Agent, with all of the Lenders at which meeting shall be reviewed
          the financial results of the previous fiscal year, the financial
          condition of the Obligors and the Operating Budget for the then
          current fiscal year of the Obligors.

13.4      Financial Covenants

13.4.1    (a)       Maximum Total Debt / EBITDA Ratio

                    ChiRex Inc. shall maintain, as of the end of each Accounting
                    Quarter to occur during the periods shown below, a Total
                    Debt/EBITDA Ratio of not more than the maximum Total
                    Debt/EBITDA Ratio shown below:

                ================================================================
                                                          Maximum Total
                                                           Debt/EBITDA
                          Period                              Ratio
                ----------------------------------------------------------------
                1st April, 1998 to 30th June, 1998          3.25 : 1
                ----------------------------------------------------------------
                1st July, 1998 to 30th September,           3.0 : 1
                1998
                ----------------------------------------------------------------
                Thereafter                                  2.5 : 1
                ================================================================

          (b)       Minimum Interest Coverage Ratio

                    ChiRex Inc. shall maintain, as of the end of each Accounting
                    Quarter to occur during the periods shown below, an Interest
                    Coverage Ratio of not less than the minimum Interest
                    Coverage Ratio shown below:


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                      ==========================================================
                                                                 Minimum
                                                                 Interest
                               Period                          Coverage Ratio

                      ----------------------------------------------------------
                      1st April, 1998 to 30th September,          3.0 : 1
                      1998
                      ----------------------------------------------------------
                      Thereafter                                  3.5 : 1
                      ==========================================================

          (c)       Calculation

(i)       The covenants contained in this Clause 13.4.1 will be tested on a
          rolling aggregate basis for the immediately preceding four quarterly
          periods ending on the last day of the relevant Accounting Quarter
          (except that Total Debt will be tested as of the last day of the
          Accounting Quarter most recently ended), in each case by reference to
          the quarterly management accounts in respect of the first three
          Accounting Quarters of each Accounting Reference Period, delivered to
          the Agent pursuant to Clauses 13.3.4(b), for the relevant period, and
          by reference to the audited accounts required to be delivered to the
          Agent pursuant to Clause 13.3.4(a) in respect of the fourth Accounting
          Quarter of each Accounting Reference Period; provided that if when the
          audited accounts become available they either demonstrate that the
          figures in any relevant quarterly management accounts utilised for any
          such calculation cannot have been substantially accurate or indicate a
          material discrepancy which is prejudicial to the Finance Parties
          between the aggregate figures for the management accounts for the four
          relevant Accounting Quarters and the aggregate audited figures, then
          the Agent shall require such adjustment to the calculations made or to
          be made as it reasonably considers appropriate to rectify such
          inaccuracy or discrepancy, and compliance with the covenants in this
          Clause 13.4.1 will be determined by reference to such adjusted
          figures.

(ii)      In the case of any component calculated by reference to management
          accounts the relevant Approved Accounting Principles will be applied
          within the reasonable parameters which may be expected of management
          accounts not the subject of audit procedures.

13.4.2    Capital Expenditure

          (a)       Before the Achievement Date only, ChiRex Inc. shall procure
                    that the Capital Expenditures (determined in


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                    accordance with Approved Accounting Principles) of the
                    ChiRex Group in each Accounting Reference Period ending
                    after the date of this Agreement do not exceed the sum of
                    (i) the amount set forth in respect thereof in the Business
                    Plan and (ii) an amount which, when added to any other
                    Restricted Payments, does not exceed in aggregate the
                    Available Amount; provided that for any Accounting Reference
                    Period of less than twelve months, the permitted amount of
                    Capital Expenditures shall be pro-rated accordingly.

          (b)       Without prejudice to the other terms of this Agreement, upon
                    each disposal of a business or company (or a material part
                    of either), the amount specified in Clause 13.4.2(a), if
                    applicable, shall be automatically reduced by the amount (if
                    any) reasonably determined by the Agent to be attributable
                    to that business, company or part thereof.

          (c)       Notwithstanding the foregoing, to the extent that the actual
                    Capital Expenditures (as so calculated) during any
                    Accounting Reference Period are less than the amount
                    permitted by Clause 13.4.2(a) for such Accounting Reference
                    Period, 100% of such unused amount shall be added to the
                    amount of permitted Capital Expenditures in any succeeding
                    year subject to no Event of Default having occurred and
                    being continuing at the time of a proposed usage of all or
                    any part of such unused amount in such succeeding year.

13.5      Additional Undertakings of ChiRex Inc.

          ChiRex Inc. undertakes that:

          (a)       Business

                    It will not engage in any business or activity other than
                    the ownership of the shares of capital stock of its
                    subsidiaries, and activities necessarily related thereto.

          (b)       Ownership

                    It will at all times own beneficially and of record 100% of
                    the outstanding shares of capital stock of ChiRex America
                    Inc. and the Borrower.

          (c)       Financial Indebtedness, Etc.


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It will procure that (i) none of ChiRex America Inc., ChiRex (Annan) Limited,
nor the Borrower has any Financial Indebtedness, except (A) in the case of the
Borrower only, its obligations in respect of the Finance Documents and the
Holdings Note, and (B) in the case of ChiRex (Annan) Limited only, its
obligations under the Finance Documents, the Annan Note and the Multiborrower
Revolving Note, (ii) the Borrower has no material assets, other than the shares
of capital stock of its subsidiaries and such assets as arise in connection with
the use of proceeds of the Advances, and (iii) ChiRex America Inc. has expenses
not exceeding GBP 2,500,000 in any Accounting Reference Period.


14.           EVENTS OF DEFAULT

14.1          List of Events

              Each of the events set out in this Clause 14.1 constitutes an
              Event of Default whether or not the occurrence of the event
              concerned is outside the control of the Obligors or any other
              person.

14.1.1        Payment Default

              Any Obligor fails to pay on the due date any amount payable by it
              under any of the Finance Documents at the place at which, and in
              the currency in which, it is expressed to be payable but, without
              prejudice to Clause 27.1, such non-payment shall not constitute an
              Event of Default if (i) it is a non-payment in respect of interest
              or fees and the relevant payment is received by the Agent within
              three Business Days of the due date for payment thereof, or (ii)
              such non-payment is caused by a technical fault in transmission of
              funds and such funds are subsequently successfully transmitted
              within one Business Day of the due date for payment thereof.

14.1.2        Breach of Other Obligations

              (a)     a breach of any provision of Clause 13.4 (Financial
                      Covenants) occurs;

              (b)     any Obligor fails to comply with any of its obligations in
                      Clause 13 (other than Clause 13.4) and, in any such case,
                      if such failure is, in the reasonable opinion of the
                      Agent, capable of remedy,


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              (c)     it is not remedied within twenty  Business Days
                      after such Obligor becomes aware of such failure; or

              (d)     any Obligor fails to comply with or perform any of its
                      other material obligations or undertakings under any of
                      the Finance Documents and, if such failure is, in the
                      reasonable opinion of the Agent, capable of remedy, it is
                      not remedied within twenty Business Days after such
                      Obligor becomes aware of such failure.

14.1.3    Misrepresentation

          Any representation, warranty or statement which is made by any Obligor
          in any of the Finance Documents or is contained in any certificate,
          statement or notice provided under or pursuant to any of the Finance
          Documents proves to be incorrect in any material respect when made (or
          deemed to be repeated) unless the circumstances giving rise to that
          default are, in the reasonable opinion of the Agent, remediable, and
          are remedied within twenty Business Days after such Obligor becoming
          aware of the same.

14.1.4    Invalidity, Unlawfulness, Etc.

          (a)       Any provision of any Finance Document is, or becomes,
                    materially invalid or unenforceable for any reason (except
                    by reason of the unavailability of specific performance or
                    other equitable remedy) or shall be repudiated or the
                    validity or enforceability of any provision of any Finance
                    Document shall at any time be contested by any Obligor party
                    thereto, or any Obligor shall deny the existence of any
                    liability or obligation on its part thereunder.

          (b)       At any time it is or becomes unlawful under the laws of any
                    applicable jurisdiction for any Obligor (other than a
                    Non-Material Subsidiary) to perform any of its material
                    obligations under any Finance Document.

          (c)       At any time any act, condition or thing required to be done,
                    fulfilled or performed in order (i) to enable any Obligor
                    lawfully to enter into, exercise its rights under and
                    perform the material obligations expressed to be assumed by
                    it in any of the Finance Documents or (ii) to ensure that
                    the material obligations expressed to be assumed by any
                    Obligor in any Finance Document are legal, valid and


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                    binding, is not done, fulfilled or performed, and if the
                    relevant matter is, in the reasonable opinion of the Agent,
                    capable of remedy, it is not remedied within fourteen
                    Business Days after the first of such Obligor becomes aware
                    of such matter.

14.1.5    Insolvency

          Subject to Clause 14.2, any Obligor is declared insolvent or is
          unable, or admits in writing its inability, to pay its debts as they
          fall due or stops or threatens to stop payment of its debts generally
          or becomes insolvent within the terms of any applicable law.

14.1.6    Receivership and Administration

          Subject to Clause 14.2,

          (a)       an application is made for the appointment of an
                    administrator (as such term is used in the Insolvency Act
                    1986) or similar official in relation to any Obligor or a
                    resolution is passed by the directors or shareholders of
                    ChiRex Inc. or any such Obligor for such an application to
                    be made;

          (b)       a liquidator, trustee, administrative or other receiver,
                    manager (being a person acting on behalf of all or any
                    creditors), judicial factor, manager for credits, or similar
                    officer is appointed in respect of (or takes possession of)
                    any Obligor or in respect of (or takes possession of) all or
                    any part of its assets; or

          (c)       any distress, execution, attachment (other than an
                    attachment or arrest to found jurisdiction) or other process
                    affects any asset of any Obligor, except where such Obligor
                    is, in good faith, reasonably contesting such distress,
                    execution, attachment or other process by proceedings
                    diligently pursued and such distress, execution, attachment
                    or other process is discharged or stayed within 30 days.

14.1.7    Compositions and Arrangements

          Subject to Clause 14.2, a moratorium or suspension of payments in
          respect of all or any classes of debts of any Obligor or a composition
          or an arrangement with creditors generally of any Obligor or any other
          arrangement whereby its affairs are submitted to the control of its
          creditors is applied for, ordered or declared.


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14.1.8    Winding-up or Similar Event

          Subject to Clause 14.2, any order is made or resolution passed or any
          legal proceedings are consented to by any Obligor or otherwise
          commenced (by way of petition or otherwise) for the suspension of
          payments generally or dissolution, termination of existence,
          liquidation, winding-up or bankruptcy of any Obligor.

14.1.9    Protection from Creditors

          Subject to Clause 14.2, any order is made, decree is passed or
          resolution is passed or other action is taken by or with respect to
          any obligor for protection from creditors of such Obligor.

14.1.10   Similar Events Elsewhere

          Subject to Clause 14.2, there occurs in relation to any Obligor or any
          of their respective assets, in any country or territory in which such
          Obligor is organised or carries on business or to the jurisdiction of
          whose courts it or any of its assets are subject, any event which
          corresponds in that country or territory with any of those mentioned
          in Clauses 14.1.5 to 14.1.9 (inclusive) (including, without
          limitation, the filing of any petition or the commencement of any
          proceedings under any U.S. federal or state bankruptcy, insolvency,
          reorganisation or other similar law), or any Obligor or its assets
          otherwise become subject, in any such country or territory, to any law
          relating to insolvency, bankruptcy or liquidation.

14.1.11   Cessation of Business

          Subject to Clause 14.2, any Obligor ceases, or threatens to cease, to
          carry on all or a substantial part of its business, other than in
          connection with a transfer by such Obligor of all or substantially all
          of its assets in accordance with Clause 13.2.8(g).

14.1.12   Compulsory Acquisition

          All or any part of the property or assets of any Obligor is
          compulsorily acquired by, or by the order of, any central or local
          governmental authority and such acquisition results in a Material
          Adverse Effect.

14.1.13   Security Interests


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          Any Security Interest securing obligations or liabilities in excess of
          GBP 2,500,000 (or its equivalent), affecting the business, undertaking
          or any of the assets of any Obligor becomes enforceable (other than by
          the exercise of a lien arising solely by operation of law in the
          ordinary course of trading where the indebtedness in respect of which
          that lien is being exercised (i) has been due for less than twenty
          days or (ii) is being contested in good faith by appropriate means)
          whether or not steps are taken to enforce the same.

14.1.14   Cross Default

          (a)       Any other Financial Indebtedness in excess of GBP 2,500,000
                    (or its equivalent) of any Obligor:-

(i)       is not paid when due or within any applicable grace period in any
          agreement relating to that Financial Indebtedness; or

(ii)      becomes due and payable (or presently capable of being declared due
          and payable) before its normal maturity or is placed upon demand
          before it is due (or any commitment for any such indebtedness is
          cancelled or suspended) by reason of a default or event of default,
          however described, or by reason of any other contractual provision
          requiring prepayment; or

          (b)       Any amount due under a WCP Facility becomes due and payable
                    (or presently capable of being declared due and payable)
                    before its normal maturity or is placed on demand before its
                    time (or any WCP Commitment for any WCP Facility is
                    cancelled or suspended) by reason of a default, however
                    described, relating thereto.

14.1.15   Auditors' Qualification

          The Auditors qualify their report on the audited consolidated
          financial statements of any Obligor in any way whatsoever.

14.1.16   Material Adverse Effect

          An event or circumstance occurs or exists which has, or is reasonably
          likely to have, a Material Adverse Effect.

14.1.17   Litigation

          Any litigation, arbitration or administrative proceedings are current
          or pending at the date of this Agreement or


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          are commenced after such date against any Obligor, which proceedings
          are reasonably likely to have a Material Adverse Effect.

14.1.18   Environmental Defaults

          (a)       any Obligor fails to comply with any Environmental Law or
                    Environmental License or becomes subject to any liability or
                    potential liability in respect of Dangerous Substances and
                    that non-compliance or liability or potential liability
                    could reasonably be expected to have a Material Adverse
                    Effect;

          (b)       if any entry on any register maintained by any government or
                    like authority for those properties deemed contaminated with
                    Dangerous Substances, including, without limitation, a
                    "black spots" list, is made in respect of any property owned
                    by any Obligor (or with respect to which property any
                    Obligor has any liability or potential liability) and as a
                    result of such registration there is a fall in the value of
                    the property in question which could reasonably be expected
                    to have a Material Adverse Effect;

          (c)       any change in applicable Environmental Law results in the
                    imposition of any liability on any Finance Party in relation
                    to any Environmental Event which liability is reasonably
                    likely to have a Material Adverse Effect; or

          (d)       any change in applicable law causes the rights of any person
                    in relation to any Environmental Claim against any Obligor
                    to rank ahead of the rights of any Finance Party against it
                    in a manner which could reasonably be expected to have a
                    Material Adverse Effect.

14.1.19   Judgement Default

          Any final judgement, decree or order (not covered by insurance) for
          the payment of money in excess of GBP 2,500,000 against all such
          persons (treating any deductibles, self-insurance or retention as not
          so covered) shall be rendered against any Obligor and shall not be
          discharged, and there shall be any period of 30 consecutive days
          following entry of such final judgement, decree or order during which
          a stay of enforcement of such final judgement, decree or order, by
          reason of a pending appeal or otherwise, shall not be in effect.


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14.1.20   Employee Benefit Plans

          An event or condition occurs or exists with respect to any Employee
          Benefit Plan and as a result of such event or condition, together with
          all other such events or conditions, a US Obligor or any ERISA
          Affiliate thereof has incurred or is reasonably likely to incur a
          liability to a Employee Benefit Plan, the PBGC or a trustee appointed
          pursuant to Section 4042 of ERISA (or any combination of the
          foregoing) which is reasonably likely to have a Material Adverse
          Effect.

14.1.21   Licenses, Authorisations, Material Agreements

          Any license, consent or authorisation necessary for the carrying on of
          the Business shall be terminated or revoked or the terms thereof shall
          be modified, or any Material Agreement shall cease to be in full force
          and effect, or the party thereto not a member of the ChiRex Group (or
          its successor) shall give notice to terminate prior to its scheduled
          termination date such Material Agreement in accordance with its terms,
          or any term of such Material Agreement shall be waived, amended or
          varied, in any case where the relevant event (taking into account any
          replacement or other compensating agreement or order secured by any
          member of the ChiRex Group) is reasonably likely to have a Material
          Adverse Effect.

14.2      Bankruptcy and Insolvency Types of Events of Default

          Notwithstanding the terms of Clauses 14.1.5 through 14.1.11
          (inclusive), the occurrence of any event described under such Clauses
          with respect to any subsidiary of the Borrower shall not constitute an
          Event of Default if the Borrower shall have, not less than twenty days
          prior to the occurrence of such event, provided evidence satisfactory
          to the Agent that, the occurrence of such event is not reasonably
          likely either to (i) have a Material Adverse Effect or (ii) to result
          in the incurrence by the Lenders of any material liabilities or
          claims.

14.3      Cancellation and Repayment

          At any time after the occurrence and during the continuance of an
          Event of Default the Agent may and, if so instructed by the Majority
          Lenders, will by notice to the Borrower:-


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          (a)       cancel any unborrowed amount of the Facilities (whereupon
                    the commitment of each Lender in respect to each Facility
                    shall be reduced to zero); and/or

          (b)       declare all Advances, accrued interest thereon and any other
                    sum accrued under this Agreement and any of the other
                    Finance Documents to be immediately due and payable,
                    whereupon they shall become so due and payable.

15.       GUARANTEE

15.1      Guarantee

          Subject to any limitations specified for the relevant Guarantor in its
          Deed of Accession and subject to Clause 15.2 below, each Guarantor
          irrevocably and unconditionally:-

          (a)       as principal obligor, waiving any benefit under applicable
                    law, guarantees to each Finance Party, prompt performance by
                    each Obligor (any reference in this Guarantee to one or more
                    Obligors shall not be construed to include a reference by a
                    Guarantor to itself in its capacity as a Guarantor), of all
                    its respective obligations under the Finance Documents (the
                    "Guarantee Obligation");

          (b)       undertakes with each Finance Party that whenever an Obligor
                    does not pay any amount when due under or in connection with
                    any Finance Document, such Guarantor shall forthwith on
                    demand by the Agent pay that amount (the "Payment
                    Obligation") as if such Guarantor instead of the relevant
                    Obligor were expressed to be the principal obligor; and

          (c)       indemnifies each Finance Party on demand against any loss or
                    liability suffered by it under the Finance Documents as a
                    result of any obligation guaranteed by such Guarantor being
                    or becoming unenforceable, invalid or illegal.

15.2      Limitation on Guarantee Obligations

          Anything contained in this Clause 15 to the contrary notwithstanding,
          if any Fraudulent Transfer Law (as hereinafter defined) is determined
          by any United States court of competent jurisdiction to be applicable
          to the obligations of any US Obligor under the Guarantee set forth in
          this Clause 15, such obligations of such US Obligor hereunder shall be
          limited to a maximum aggregate amount equal to the largest


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          amount that would not render its obligations hereunder subject to
          avoidance as a fraudulent transfer or conveyance under Section 548 of
          Title 11 of the United States Code or any applicable provisions of
          comparable state law, to the extent applicable to any respective
          guarantee of any US Obligor (collectively, the "Fraudulent Transfer
          Laws"), in each case after giving effect to all other liabilities of
          such US Obligor, contingent or otherwise, that are relevant under the
          Fraudulent Transfer Laws (specifically excluding, however, any
          liabilities of such US Obligor in respect of intercompany indebtedness
          to any other member of the ChiRex Group to the extent that such
          indebtedness would be discharged in an amount equal to the amount paid
          by such US Obligor hereunder) and after giving effect as assets to the
          value (as determined under the applicable provisions of the Fraudulent
          Transfer Laws) of any rights to subrogation, reimbursement,
          indemnification or contribution of such US Obligor pursuant to
          applicable law or pursuant to the terms of any agreement.

15.3      Joint and Several Liability

          Subject to any limitations specified for the relevant Obligor in its
          Deed of Accession, if applicable, each obligation expressed under this
          Agreement to be an obligation of the Obligors shall be the joint and
          several obligation of each Obligor.

15.4      Continuing Guarantee

          This guarantee is a continuing guarantee and will extend to the
          ultimate balance of all sums payable by the Obligors under the Finance
          Documents, regardless of any intermediate payment or discharge in
          whole or in part.

15.5      Reinstatement

          (a)       Where any discharge (whether in respect of the obligations
                    of any Obligor or any security for those obligations or
                    otherwise) is made in whole or in part or any arrangement is
                    made on the faith of any payment, security or other
                    disposition which is avoided or must be restored on
                    insolvency, liquidation or otherwise without limitation, the
                    liability of each Guarantor under this Clause 15 shall
                    continue as if the discharge or arrangement had not
                    occurred.

          (b)       Each Finance Party may concede or compromise any claim that
                    any payment, security or other disposition is liable to
                    avoidance or restoration.

15.6      Waiver of Defences


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          The obligations of each Guarantor under this Clause 15 will not be
          affected by, and each Guarantor waives its rights (to the fullest
          extent permitted by law) in connection with, any act, omission, matter
          or thing which, but for this provision, would reduce, release or
          prejudice any of its obligations under this Clause 15 or prejudice or
          diminish those obligations in whole or in part, including (whether or
          not known to it or any Finance Party):-

          (a)       any time or waiver granted to, or composition with, any
                    Obligor or any other person;

          (b)       the taking, variation, compromise, exchange, renewal or
                    release of, or refusal or neglect to perfect, take up or
                    enforce, any rights against, or security over assets
                    (including any balance of any deposit or account or credit
                    on the books of any Finance Party or other person in favour
                    of any Obligor or any other person) of, any Obligor or other
                    person or any non-presentation or non-observance of any
                    formality or other requirement in respect of any instrument
                    or any failure to realise the full value of any security;

          (c)       any incapacity or lack of powers, authority or legal
                    personality of or dissolution or change in the members or
                    status of any Obligor or any other person;

          (d)       any variation (however fundamental) or replacement of a
                    Finance Document or any other document or security so that
                    references to that Finance Document in this Clause 15 shall
                    include each variation or replacement;

          (e)       any unenforceability, illegality or invalidity of any
                    obligation of any person under any Finance Document or any
                    other document or security, to the intent that such
                    Guarantor's obligations under this Clause 15 shall remain in
                    full force and its guarantee be construed accordingly, as if
                    there were no unenforceability, illegality or invalidity; or

          (f)       any postponement, discharge, reduction, non-provability or
                    other similar circumstance affecting any obligation of any
                    Obligor under a Finance Document resulting from any
                    insolvency, liquidation or dissolution proceedings or from
                    any law, regulation or order so that each such obligation
                    shall for the purposes of each Guarantor's


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                    obligations under this Clause 15 be construed as if there
                    were no such circumstance.

15.7      Immediate recourse

          Each Guarantor waives any right it may have of first requiring any
          Finance Party (or any trustee or agent on its behalf) to (i) proceed
          against or enforce any other rights or security or claim payment from
          any person, or (ii) pursue any other remedy in the power of any
          Finance Party whatsoever, before enforcing its rights against such
          Guarantor under this Clause 15.

15.8      Appropriations

          Until all amounts which may be or become payable by the Obligors under
          or in connection with the Finance Documents have been irrevocably paid
          in full, each Finance Party (or any trustee or agent on its behalf)
          may:-

          (a)       refrain from applying or enforcing any other moneys,
                    security or rights held or received by that Finance Party
                    (or any trustee or agent on its behalf) in respect of those
                    amounts, or apply and enforce the same in such manner and
                    order as it sees fit (whether against those amounts or
                    otherwise) and no Guarantor shall be entitled to the benefit
                    of the same; and

          (b)       hold in a market rate interest-bearing suspense account any
                    moneys received from each Guarantor or on account of such
                    Guarantor's liability under this Clause 15, with interest
                    accruing thereon for the account of such Guarantor at a rate
                    determined by such Finance Party, acting reasonably, to be
                    appropriate in the circumstances.

15.9      Non-competition

          Until all amounts which may be or become payable by the Obligors under
          or in connection with the Finance Documents have been irrevocably paid
          in full, each Guarantor shall not, after a claim has been made or by
          virtue of any payment or performance by it under this Clause 15:-

          (a)       be subrogated to any rights, security or moneys held,
                    received or receivable by any Finance Party (or any trustee
                    or agent on its behalf) or be entitled to any right of
                    contribution or indemnity


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                    in respect of any payment made or moneys received on account
                    of such Guarantor's liability under this Clause 15;

          (b)       without the consent of the Agent, claim, rank, prove or vote
                    as a creditor of any Obligor or its estate in competition
                    with any Finance Party (or any trustee or agent on its
                    behalf); or

          (c)       receive, claim or have the benefit of any payment,
                    distribution or security from or on account of any Obligor,
                    or exercise any right of set-off as against any Obligor.

          Each Guarantor shall hold in trust for and forthwith pay or transfer
          to the Agent for the Finance Parties any payment or distribution or
          benefit of security received by it contrary to this Clause 15.9.

15.10     Additional Security, Relation to Other Obligations of Guarantors

          This guarantee is in addition to and shall not in any way be
          prejudiced by any other security now or hereafter held by any Finance
          Party.

16.       THE AGENT AND THE OTHER FINANCE PARTIES

16.1      Appointment and duties of the Agent, Security Agent and Joint
          Arrangers

16.1.1    Each Lender hereby appoints (i) Bankers Trust Company as Agent, to act
          as its agent in connection with the Finance Documents, (ii) Bankers
          Trust Company as Security Agent, to act as security agent for purposes
          of the Security Documents, and (iii) Bankers Trust International PLC
          and Midland Bank plc to act as Joint Arrangers, under and in
          connection with the Finance Documents, and irrevocably authorises
          Bankers Trust Company for and on its behalf to exercise such rights,
          powers and discretions as are specifically delegated to it by the
          terms of the Finance Documents, together with all such rights, powers
          and discretions as are incidental thereto, and to give a good
          discharge for any moneys payable under the Finance Documents. The
          Lenders empower the Agent or the Security Agent, as the case may be,
          on the broadest terms to take such actions and to exercise any and all
          rights derived from this Agreement, including, but not limited to (i)
          the enforcement of the Finance Documents, and (ii) the


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          sending or receiving of whatever notices or communications the Agent
          may deem necessary or advisable.

16.1.2    The Agent will act solely as agent for the Lenders in carrying out its
          functions as agent under the Finance Documents and will exercise the
          same care as it would in dealing with a credit for its own account.

16.1.3    The relationship between the Lenders and the Agent is that of
          principal and agent only. The Agent shall not have, nor be deemed to
          have assumed, any obligations to, or trust or fiduciary relationship
          with, the other Finance Parties or ChiRex Inc. or any member of the
          ChiRex Group other than those for which specific provision is made by
          the Finance Documents.

16.1.4    References in this Clause 16 to "Agent" shall be deemed also to be
          references to the Agent in its capacities as Security Agent and Joint
          Arranger (save where specific reference is made to the contrary),
          notwithstanding the use of the expression "the Agent and the Security
          Agent" in certain provisions of the Finance Documents.

16.2      Agent's Duties

          The Agent shall:-

16.2.1    promptly send to each Lender details of each communication received by
          it from ChiRex Inc., the Borrower or the members of the ChiRex Group
          under the Finance Documents, except that details of any communication
          relating to a particular Lender shall be sent to that Lender only;

16.2.2    promptly send to each Lender a copy of any legal opinion delivered
          under this Agreement or any of the other Finance Documents and of any
          document or information received by it pursuant to Clause 13.3
          (Information and Accounting Undertakings) or (if requested) pursuant
          to Clause 4.1;

16.2.3    subject to those provisions of this Agreement which require the
          consent of all the Lenders, act in accordance with any instructions
          from the Majority Lenders or, if so instructed by the Majority
          Lenders, refrain from exercising a right, power or discretion vested
          in it under this Agreement or any of the Finance Documents;

16.2.4    have only those duties, obligations and responsibilities expressly 
          specified in the Finance Documents; and


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16.2.5    without prejudice to any other clause hereof (including without
          limitation Clauses 16.3.5, 16.4(c) and 16.6.3), promptly notify each
          Lender of the occurrence of any Event of Default or Potential Event of
          Default of which an officer of the Agent responsible for the
          administration of this Agreement becomes aware.

16.3      Agent's and Security Agent's Rights

          The Agent and the Security Agent, as the case may be, may:-

16.3.1    perform any of its duties, obligations and responsibilities under the
          Finance Documents by or through its personnel, delegates or agents (on
          the basis that the Agent and/or Security Agent may extend the benefit
          of any indemnity received by it hereunder to its personnel, delegates
          or agents);

16.3.2    refrain from exercising any right, power or discretion vested in it
          under the Finance Documents until it has received instructions from
          the Majority Lenders, or where relevant, all the Lenders;

16.3.3    unless it has received notice in writing to the contrary treat (a) the
          Lender which makes available any portion of an Advance as the person
          entitled to repayment of that portion and (b) the office set under a
          Lender's name in Schedule 1 (or, in the case of a Transferee, at the
          end of the Transfer Certificate to which it is a party as Transferee)
          as its Lending Office;

16.3.4    refrain from doing anything which would or might in its opinion be
          contrary to any law, regulation, directive, judgement or decree of any
          court of any jurisdiction or otherwise render it liable to any person
          and may do anything which is in its opinion necessary to comply with
          any such law, regulation, judgement, decree or directive;

16.3.5    assume that no Event of Default or Potential Event of Default has
          occurred unless an officer of the Agent while active on the account of
          the Borrower acquires actual knowledge to the contrary;

16.3.6    refrain from taking any step (or further step) to protect or enforce
          the rights of any Lender under this Agreement or any of the other
          Finance Documents until it has been indemnified and/or secured to its
          satisfaction against any and all costs, losses, expenses or
          liabilities (including legal fees) which it would or might sustain or
          incur as a result;


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16.3.7    rely on any communication or document believed by it to be genuine and
          correct and to have been communicated or signed by the person to whom
          it purports to be communicated and signed;

16.3.8    rely as to any matter of fact which might reasonably be expected to be
          within the knowledge of the Borrower on a statement by or on behalf of
          the Borrower;

16.3.9    obtain and pay for such legal or other expert advice or services as
          may seem necessary to it or desirable and rely on any such advice.

16.3.10   accept without enquiry such title as the Obligors may have to any
          asset or assets intended to be the subject of the security created by
          the Security Documents; and

16.3.11   hold or deposit any title deeds, the Security Documents or any other
          documents in connection with any of the assets charged by the Security
          Documents with any banker or banking company or any company whose
          business includes undertaking the safe custody of deeds or documents
          or with any lawyer or firm of lawyers and it shall not be responsible
          for or be required to insure against any loss incurred in connection
          with any such holding or deposit and it may pay all sums required to
          be paid on account or in respect of any such deposit.

16.4      Exoneration of Agent, Security Agent and Joint Arrangers

          Neither the Agent nor the Security Agent nor the Joint Arrangers nor
          any of their respective personnel or agents:-

          (a)       shall be responsible for the adequacy, accuracy or
                    completeness of any representation, warranty, statement or
                    information in the Information Memorandum, any of the
                    Finance Documents or any notice or other document delivered
                    under the Finance Documents;

          (b)       shall be responsible for the execution, delivery, validity,
                    legality, adequacy, enforceability or admissibility in
                    evidence of any of the Finance Documents;


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          (c)       shall be obliged to enquire as to the occurrence or
                    continuation of an Event of Default or a Potential Event of
                    Default;

          (d)       shall be responsible for any failure of any member of the
                    ChiRex Group or any of the Lenders duly and punctually to
                    observe and perform their respective obligations under the
                    Finance Documents;

          (e)       shall be responsible for the consequences of relying on the
                    advice of any professional advisers selected by any of them
                    in connection with the Finance Documents;

          (f)       shall be liable for acting (or refraining from acting) in
                    what it believes to be in the best interests of the Lenders
                    in circumstances where it has been unable, or it is not
                    practicable, to obtain the instructions of the Lenders or
                    the Majority Lenders (as the case may be); or

          (g)       shall be liable for anything done or not done by it under or
                    in connection with the Finance Documents save in the case of
                    its own negligence or wilful misconduct.

16.5      The Agent, the Security Agent and the Joint Arrangers Individually

16.5.1    If it is a Lender, each of the Agent, the Security Agent and each
          Joint Arranger shall have the same rights and powers under the Finance
          Documents as any other Lender and may exercise those rights and powers
          as if it were not also acting as Agent, Security Agent or Joint
          Arranger.

16.5.2    Each of the Agent, the Security Agent and each Joint Arranger may:-

          (a)       retain for its own benefit (and without liability to
                    account) any fee or other sum receivable by it for its own
                    account; and

          (b)       accept deposits from, lend money to, provide any advisory,
                    trust or other services to or engage in any kind of banking
                    or other business with any party to this Agreement, or any
                    subsidiary or affiliate of any party (and, in each case, may
                    do so without liability to account).

16.6      Communications and Information


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16.6.1    All communications to any member of the ChiRex Group are to be made by
          or through the Agent. Each Finance Party will notify the Agent of, and
          provide the Agent with a copy of, any communication between such
          Finance Party and the relevant member of the ChiRex Group or any other
          of the Finance Parties on any matter concerning the Facilities or the
          Finance Documents.

16.6.2    The Agent will not be obliged to transmit to the other Finance Parties
          any information in any way relating to any of the parties to the
          Finance Documents which the Agent may have acquired otherwise than in
          connection with the Facilities or the Finance Documents.

16.6.3    In acting as Agent for the Lenders, the Agent's banking division shall
          be treated as a separate entity from any other of its divisions (or
          similar unit of the Agent in any subsequent re-organisation),
          subsidiaries or affiliates (the "Other Divisions") and, in the event
          that the Agent should act for any member of the ChiRex Group in a
          corporate finance or other advisory capacity ("Advisory Capacity"),
          any information given by any of them to one of the Other Divisions is
          to be treated as confidential and will not be available to the Finance
          Parties without the consent of the person for whom the Agent is acting
          in an Advisory Capacity, provided that:-

          (a)       the consent of that person shall not be required in relation
                    to any information which the Agent in its discretion
                    determines relates to an Event of Default or a Potential
                    Event of Default or in respect of which the Lenders have
                    given a confidentiality undertaking in a form satisfactory
                    to the Agent and the Borrower or that person; and

          (b)       if representatives or employees of the Agent receive
                    information in relation to an Event of Default or a
                    Potential Event of Default while acting in an Advisory
                    Capacity they will not be obliged to disclose such
                    information to representatives or employees of the Agent in
                    their capacity as agent bank, security agent or joint
                    arranger hereunder or to any of the Lenders if to do so
                    would breach any rule or regulation or fiduciary duty
                    imposed upon such persons.

16.7      Non-Reliance on Agent, Security Agent or Joint Arrangers

          Each Lender confirms in favour of the Agent, Security Agent and Joint
          Arrangers that it is (and will at all


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          times continue to be) solely responsible for making its own
          independent investigation and appraisal of the business, operations,
          financial condition, creditworthiness, status and affairs of the
          ChiRex Group and has not relied, and will not at any time rely on the
          Agent or the Security Agent or the Joint Arrangers:-

16.7.1    to provide it with any information relating to the business,
          operations, financial condition, creditworthiness, status and affairs
          of the ChiRex Group, whether coming into its possession before or
          after the making of any Advance, except as otherwise specifically
          provided herein; or

16.7.2    to check or enquire into the adequacy, accuracy or completeness of any
          information provided by the ChiRex Group under or in connection with
          this Agreement or any other Finance Document (whether or not such
          information has been or is at any time circulated to it by the Agent),
          including, without limitation, that contained in the Information
          Memorandum; or

16.7.3    to assess or keep under review the business, operations, financial
          condition, creditworthiness, status or affairs of the ChiRex Group.

16.8      Indemnity to Agent, Security Agent and Joint Arrangers

16.8.1    Each Lender shall on demand fully indemnify the Agent, the Security
          Agent and the Joint Arrangers and their respective officers, employees
          and affiliates (collectively the "Agency Indemnitees") in the
          proportion which its Relevant Amount bears to the Relevant Amounts of
          all the Lenders at the relevant time against any cost, expense or
          liability sustained or incurred by any of the Agency Indemnitees in
          their respective capacities as Agent, Security Agent and Joint
          Arrangers as a consequence of or in connection with complying with any
          instructions from the Lenders or the Majority Lenders (as the case may
          be) or otherwise sustained or incurred in their respective capacities
          as Agent, Security Agent and Joint Arrangers in connection with the
          Finance Documents or its respective duties, obligations and
          responsibilities under the Finance Documents, except to the extent
          that they are sustained or incurred principally as a result of the
          negligence or wilful misconduct of such Agency Indemnitee as finally
          determined by a court having jurisdiction (the determination not being
          subject to appeal).

16.8.2    The provisions of Clause 16.8.1 are without prejudice to the
          obligations of the Borrower to indemnify the Agency


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          Indemnitees pursuant to Clause 27 and the Borrower will reimburse each
          Lender on demand for any payment made by that Lender pursuant to
          Clause 16.8.1.

16.9      Termination and Resignation of Agency: Appointment of Successor
 
16.9.1    The Agent may resign its appointment at any time by giving not less
          than 30 days' notice to the Lenders and the Borrower.

16.9.2    A successor Agent shall be selected:-

          (a)       by the retiring Agent (following consultation with the
                    Borrower) nominating one of its subsidiaries or affiliates
                    as successor Agent in its notice of resignation; or

          (b)       if the retiring Agent makes no such nomination, by the
                    Majority Lenders nominating one of the Lenders as successor
                    Agent (following consultation with the Borrower); or

          (c)       if the Majority Lenders have failed to nominate a successor
                    Agent within 30 days of the date of the retiring Agent's
                    notice of resignation, by the retiring Agent nominating a
                    financial institution of good standing to be the successor
                    Agent.

16.9.3    The resignation of the retiring Agent and the appointment of the
          successor Agent will only become effective upon the successor Agent
          accepting its appointment as Agent in writing at which time:-

          (a)       the successor Agent will become bound by all the obligations
                    of the Agent and become entitled to all the rights,
                    privileges, powers, authorities and discretions of the Agent
                    hereunder;

          (b)       the agency of the retiring Agent will terminate but without
                    prejudice to any liabilities which the retiring Agent may
                    have incurred or the indemnities to which the retiring Agent
                    may be entitled prior to the termination of its agency; and

          (c)       the retiring Agent will be discharged from any further
                    liability or obligation under or in connection with the
                    Finance Documents (save that the outgoing Agent shall pay to
                    the successor a pro rata proportion of the agency fee paid
                    under Clause 11.1.1(c)).


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16.9.4    The retiring Agent will co-operate with the successor Agent in order
          to ensure that its functions are transferred to the successor Agent
          without disruption to the service provided to the ChiRex Group and the
          Lenders and will promptly make available to the successor Agent such
          documents and records as have been maintained in connection with this
          Agreement in order that the successor Agent is able to discharge its
          functions.

16.9.5    The provisions of this Agreement will continue in effect for the
          benefit of any retiring Agent in respect of any actions taken or
          omitted to be taken by it or any event occurring before the
          termination of its agency.

16.10     Resignation of Security Agent

          The Security Agent may resign its appointment in exactly the same
          manner as set out in relation to the Agent in Clause 16.9 above except
          that the Security Agent's resignation shall not take effect until all
          necessary deeds and documents have been entered into in order to
          substitute its successor as holder of the security comprised in the
          Security Documents.

16.11     Payments to Finance Parties

16.11.1   The Agent will account to the other Finance Parties for their due
          proportion of all sums received by the Agent for such Finance Parties,
          whether by way of repayment of principal or payment of interest,
          commitment commission, fees or otherwise.

16.11.2   Save as otherwise specifically agreed between the Agent and the other
          Finance Parties in the case of any arrangement fee, the Agent may
          retain for its own use and benefit, and shall not be liable to account
          to the other Finance Parties for all or any part of, any sums received
          by it by way of agency fee or any other fee or by way of reimbursement
          of expenses incurred by it.

16.12     Change of Office of Agent, Security Agent or Joint Arrangers

          The Agent, the Security Agent and either Joint Arranger may at any
          time and from time to time in their respective sole discretion by
          written notice to the Borrower and each of the other Finance Parties
          designate a different office from which their respective duties as
          Agent,


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          Security Agent or Joint Arranger will thereafter be performed.

17.       EVIDENCE OF INDEBTEDNESS

          In any proceedings relating to this Agreement, a statement as to any
          amount due to any Finance Party under this Agreement which is
          certified as being correct by an officer of the Agent and a statement
          as to any amount due to a Finance Party under this Agreement which is
          certified as being correct by an officer of that Finance Party shall
          in the absence of manifest error, unless otherwise provided in this
          Agreement, be prima facie evidence of the amount so due and that such
          amount is in fact due and payable.

18.       APPLICATION OF MONEYS

          If any sum paid or recovered in respect of the liabilities of the
          Obligors under any of the Finance Documents is less than the amount
          then due, the Agent shall apply that sum in the following order:-

          (a)       first to any unpaid fees and reimbursement of unpaid
                    expenses of the Agent and the Security Agent;

          (b)       secondly to any unpaid fees and reimbursement of unpaid
                    expenses of the Lenders;

          (c)       thirdly to unpaid interest;

          (d)       fourthly to unpaid principal; and

          (e)       fifthly to other amounts due under the Finance Documents;

          in each case pro rata to the outstanding amounts owing to the Finance
          Parties under the Finance Documents taking into account any
          applications under this Clause 18.

19.       PRO RATA PAYMENTS

19.1      If any amount owing by any Obligor under any Finance Document to a
          Lender (the "Recovering Lender") is discharged by payment, set-off,
          use of cash collateral or any other manner other than through the
          Agent in accordance with Clause 9.1.1 (such amount being referred to
          in this Clause 19.1 as the "Recovery"), then:-


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          (a)       within two Business Days of receipt of the Recovery, the
                    Recovering Lender shall pay to the Agent an amount equal (or
                    equivalent) to such Recovery;

          (b)       the Agent shall treat such payment as if it were part of the
                    payment to be made by the Borrower to the Lenders rateably
                    in accordance with their respective Commitments; and

          (c)       save for any receipt by the Recovering Lender as a result of
                    the operation of paragraph (b) above, as between the members
                    of the ChiRex Group and the Recovering Lender the Recovery
                    shall be treated and deemed as not having been paid.

19.2      Each Lender shall notify the Agent promptly of any such Recovery by
          that Lender other than by payment through the Agent. If any Recovery
          subsequently has to be wholly or partly refunded by the Recovering
          Lender which paid an amount equal thereto to the Agent under Clause
          19.1(a), each Lender to which any part of that amount was distributed
          shall, on request from the Recovering Lender, repay to the Recovering
          Lender such Lender's pro rata share of the amount which has to be
          refunded by the Recovering Lender.

19.3      Each Lender shall on request supply to the Agent such information as
          the Agent may from time to time request for the purpose of this Clause
          19. Notwithstanding the foregoing provisions of this Clause 19, no
          Recovering Lender shall be obliged to share with another person any
          Recovery which it receives pursuant to legal proceedings taken by it
          to recover any sums owing to it under the Finance Documents where such
          other person has a legal right to, but does not, either join in such
          proceedings or commence and diligently pursue separate proceedings to
          enforce its rights in the same or another court (unless the
          proceedings instituted by the Recovering Lender are instituted by it
          without prior notice having been given to such other person through
          the Agent).

19.4      Failure by any Recovering Lender to comply with any of the provisions
          of this Clause 19 shall not release any other Recovering Lender from
          any of its obligations or liabilities under this Clause 19.

19.5      Each party to this Agreement agrees to take all steps required of it
          pursuant to Clause 19.1, and to use its reasonable endeavours to
          obtain any consents or authorisations which may at any relevant time
          be


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          required, for any payment by it pursuant to this Clause 19.

19.6      The provisions of this Clause 19 shall not, and shall not be construed
          so as to, constitute a charge by a Lender over all or any part of a
          sum received or recovered by it in the circumstances mentioned in this
          Clause 19.

20.       SET-OFF

          Any Finance Party may without notice to any members of the ChiRex
          Group, following the giving of notice by the Agent pursuant to Clause
          14.3, combine, consolidate or merge all or any of the accounts of any
          member of the ChiRex Group with, and liabilities to, that Finance
          Party and may set off or otherwise retain or transfer any sum standing
          to the credit of any such accounts in or towards the satisfaction of
          any of the liabilities of such member of the ChiRex Group to that
          Finance Party under the Finance Documents (whether or not such
          liabilities are then due for payment), and may do so notwithstanding
          that the balances on such accounts and the liabilities may not be
          expressed in the same currency, and each Finance Party is hereby
          authorised to effect any necessary conversions at the Agent's spot
          rate of exchange then prevailing.

21.       NOTICES

21.1      Save as specifically otherwise provided in this Agreement or agreed
          with the Agent any notice, demand or other communication to be served
          under this Agreement may be served upon any party hereto only by
          posting by first class (or air mail) post or by delivering the same in
          person or by courier or sending the same by facsimile transmission to
          the party to be served at its address or facsimile number given in the
          relevant Finance Document or at such other address or number as it may
          from time to time notify in writing to the other parties hereto. As
          regards the initial parties to this Agreement, their respective
          addresses and numbers are set out under their respective names in
          Schedule 1 or in the signature pages of this Agreement.

21.2      A notice or demand served by first class (or air mail) post shall be
          deemed duly served upon receipt, a notice or demand served in person
          or by courier shall be deemed duly served when delivered and a notice
          or demand sent by facsimile transmission shall be deemed to have been
          served at the time of transmission unless served on a


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          non-Business Day or after 5.00 p.m. at the place in which the
          recipient is located in which case it will be deemed served at 9.00
          a.m. at the place in which the recipient is located on the following
          Business Day.

21.3      In proving service of any notice or demand it will be sufficient to
          prove, in the case of a letter, that such letter was properly stamped
          or franked first class (or with appropriate air mail postage),
          addressed and placed in the post, in the case of a notice or demand
          served by courier that it was delivered by the courier company and, in
          the case of a facsimile transmission, that such facsimile was duly
          transmitted to a current facsimile number of the addressee at the
          address referred to above and the transmission report indicates that
          it was correctly sent and received.

22.       NO IMPLIED WAIVERS

22.1      No failure or delay by the Agent, the Security Agent or the Joint
          Arrangers or any other Finance Party in exercising any right, power or
          privilege under any of the Finance Documents shall operate as a waiver
          thereof nor shall any single or partial exercise of any right, power
          or privilege preclude any further exercise thereof or the exercise of
          any other right, power or privilege.

22.2      The rights and remedies provided in the Finance Documents are
          cumulative and not exclusive of any rights and remedies provided by
          law and all such rights and remedies howsoever arising will, save
          where expressly provided to the contrary therein, be available to the
          Finance Parties severally and any Finance Party shall be entitled to
          commence proceedings in connection therewith in its own name.

23.       INVALIDITY OF ANY PROVISION

          If any of the provisions of this Agreement become invalid, illegal or
          unenforceable in any respect under any law, the validity, legality and
          enforceability of the remaining provisions shall not in any way be
          affected or impaired.

24.       CONFIDENTIALITY

24.1      Each of the Finance Parties agrees with the Borrower to hold
          confidential all information which they acquire


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          under or in connection with the Finance Documents save to the extent
          they are required by law or regulation, or are requested by any
          regulator with jurisdiction over, or over any business of, the
          relevant Finance Party or any of its subsidiaries or affiliates, or
          where necessary in connection with litigation, to disclose the same or
          the same comes into the public domain (otherwise than as a result of a
          breach of this Clause 24).

24.2      Nothing in Clause 24.1 shall restrict any Finance Party from
          disclosing information in accordance with Clause 25.4 (Disclosure of
          Information).

24.3      Except to the extent required by law, all public announcements in
          relation to this Agreement shall be made through the Agent. The Agent
          will not make any written public announcement in relation to this
          Agreement without first having the text of the announcement approved
          by ChiRex Inc. (such approval not to be unreasonably withheld or
          delayed).

25.       CHANGES TO PARTIES

25.1      No Assignment by the ChiRex Group

          None of the members of the ChiRex Group may assign or transfer all or
          part of their rights or obligations under this Agreement or any of the
          other Finance Documents.

25.2      Lenders

25.2.1    A Lender (a "Transferor") may at any time, following consultation with
          the Borrower, assign or otherwise transfer (together, "Transfer") all
          or any part of its rights or obligations under the Finance Documents
          to any person which is then a Qualifying Lender (a "Transferee"),
          subject to the other terms of this Clause 25, provided that unless the
          Borrower and the Agent otherwise agree, any Transfer by a Transferor
          (i) in relation to all Facilities other than a WCP Facility, must, to
          the extent it has rights and/or obligations in respect of one or more
          Facility, be in relation to all Facilities and any Transfer shall be
          for the same proportion of the Transferor's rights and obligations in
          each Facility, and (ii) in relation to a WCP Facility must be in
          respect of that entire WCP Facility and that Transferor's entire WCP
          Commitment thereunder.

25.2.2    A Transfer of obligations of the Lenders shall only be effective if
          made in accordance with Clause 25.3


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          (Substitution Provisions) or if the Transferee has, prior to the
          Transfer taking effect, confirmed in writing to the Agent (acting on
          behalf of all the other Lenders) and to the Borrower that it
          undertakes to be bound by the terms of each of the Finance Documents
          binding upon it as a Lender in form and substance satisfactory to the
          Agent. On any such Transfer being made, the Transferor shall be
          relieved of its obligations to the extent that they are transferred to
          the Transferee.

25.3      Substitution Provisions

25.3.1    A Transferor may transfer, upon notice being given by the Agent to the
          other parties hereto as provided below, all or any of its rights and
          obligations under the Finance Documents to a Transferee by means of a
          novation effected by the Agent executing a Transfer Certificate which
          has been duly completed and signed on behalf of both the Transferee
          and the Transferor. For the avoidance of doubt, the Agent shall not be
          obliged to execute a Transfer Certificate unless the identity of the
          Transferee named therein is satisfactory to the Agent, and nothing in
          this Clause 25.3.1 shall be deemed to authorise the Agent to sign a
          Transfer Certificate which has not been signed on behalf of a
          Transferee and Transferor.

25.3.2    On the later of (i) the date specified in the Transfer Certificate as
          being the date on or as from which the substitution under this Clause
          25.3 is to take effect and (ii) the date on which the Agent executes
          the Transfer Certificate, the following shall occur:-

          (a)       to the extent that in the Transfer Certificate the
                    Transferor seeks to transfer its rights and obligations
                    under the Finance Documents, the members of the ChiRex Group
                    and the Transferor shall each be released from further
                    obligations to each other under the Finance Documents (and
                    the appropriate reduction shall be made to the Commitment of
                    the Transferor) and their respective rights against each
                    other shall be cancelled (such rights and obligations beings
                    referred to in this Clause 25.3.2 as "Discharged Rights and
                    Obligations");

          (b)       the members of the ChiRex Group and the Transferee shall
                    each assume obligations towards each other and acquire
                    rights against each other which differ from the Discharged
                    Rights and Obligations only in so far as the members of the
                    ChiRex Group and such Transferee have assumed and acquired
                    the same in


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                    place of the members of the ChiRex Group and the Transferor;

          (c)       the Agent, the Security Agent, the Joint Arrangers, the
                    Transferee and the other Lenders shall acquire the same
                    rights and assume the same obligations between themselves as
                    they would have acquired and assumed had the Transferee been
                    an original party hereto as a Lender with the rights and
                    obligations acquired or assumed by it as a result of the
                    novation; and

          (d)       on the date upon which such transfer takes effect, the
                    Transferee shall pay to the Agent for its own account a
                    transfer fee of GBP 500, except that no fee shall be payable
                    in respect of a transfer which occurs not later than six
                    months after the Initial Drawdown Date.

25.3.3    Nothing in this Agreement or any other Finance Document shall oblige a
          Transferor or cause a Transferor to be liable:-

          (a)       to accept a re-assignment or re-transfer from a Transferee
                    of any of the rights or obligations assigned, transferred or
                    novated pursuant to this Clause 25; or

          (b)       to support any losses incurred by a Transferee by reason of
                    the non-performance by any member of the ChiRex Group of
                    their obligations under any of the Finance Documents.

25.3.4    Each of the parties hereto (other than the Transferor and the
          Transferee) authorises the Agent to execute on its behalf any Transfer
          Certificate which has been duly completed in accordance with this
          Clause 25.3 and executed on behalf of each of the Transferor and the
          Transferee.

25.3.5    The Agent shall promptly notify the other parties hereto of the
          receipt and execution by it on their behalf of any Transfer
          Certificate and shall supply a copy of the Transfer Certificate to the
          Borrower.

25.4      Disclosure of Information

          Each Lender may disclose to a proposed assignee or transferee or any
          sub-participant, risk participant or other participant proposing to
          enter or having entered into a contract with such Lender regarding the
          Finance Documents any information in the possession of such


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          Lender relating to the ChiRex Group (and any member of it) as it sees
          fit subject to such person agreeing in writing to be bound by the
          confidentiality provisions set out in Clause 24.

25.5      The Agent and the Reference Lenders

25.5.1    Changes to the Agent and the office through which the Agent acts may
          be effected pursuant to Clauses 16.9 and 16.12 respectively.

25.5.2    If a Reference Lender ceases to be one of the Lenders or, if a
          Reference Lender is not itself a Lender but an affiliate of a Lender
          and such Lender ceases to be one of the Lenders, then:-

          (a)       the Lender or, as the case may be, affiliate of the Lender
                    concerned shall cease to be a Reference Lender; and

          (b)       the Agent shall in consultation with the Borrower appoint
                    another Lender or an affiliate of another Lender to be a
                    Reference Lender.

26.       LENDER DECISIONS

26.1      Subject to Clauses 26.2 and 26.3, any provision of this Agreement or
          any of the other Finance Documents may be amended, waived, varied or
          modified with the agreement of the Majority Lenders.

26.2      The following matters shall require the unanimous agreement of all of
          the Lenders:-

26.2.1    any increase in any Commitment of any Lender;

26.2.2    any extension of any scheduled date for payment of any sum due, owing
          or payable to any Lender;

26.2.3    any reduction in the amount, or change in currency, of any payment of
          principal, interest, fees or commissions or other amounts payable
          hereunder by any party;

26.2.4    any amendment, variation or modification of this Clause 26, Clause 19
          (Pro Rata Payments), Clause 20 (Set-off), Clause 25.1 (Assignment by
          the Borrower, Etc.) or to the definition of Majority Lenders;


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26.2.5    any matter which, by the terms of this Agreement as at the date
          hereof, is stated to be subject to the consent of all Lenders;

26.3      Any amendment, waiver, variation or modification of Clause 16 (The
          Agent and the other Finance Parties) may not be effected without the
          agreement of the Agent (giving effect to Clause 16.1.4).

26.4      Subject to any provision of the Finance Documents entitling or
          obliging the Agent or the Security Agent to grant releases or permit
          any disposal to take place, any question which relates to the release
          or material variation of any security held by the Security Agent shall
          require the agreement of the Majority Lenders, failing which no such
          release or variation may be effected.

27.       INDEMNITIES

27.1      General Indemnity and Breakage Costs

          The Borrower will fully indemnify each of the Finance Parties, and
          their respective officers, employees, subsidiaries and affiliates
          (collectively the "Finance Indemnitees") from and against any expense,
          loss, damage or liability (including without limitation any arising
          from any actual or alleged breach of any Environmental Laws) which any
          of the Finance Indemnitees may incur as a consequence of or in
          connection with (i) the provision and/or Syndication of the Facilities
          or the use of proceeds thereof (including the distribution of the
          Information Memorandum), or (ii) the execution, delivery or
          performance of any of the Finance Documents, other than, in the case
          of a Finance Indemnitee, any such expense, loss, damage or liability
          which is finally determined by a court having jurisdiction (the
          determination not being subject to appeal) to have resulted
          principally from the negligence or wilful misconduct of such Finance
          Indemnitee or which is otherwise reimbursed by a member of the ChiRex
          Group under the Finance Documents. The Borrower will further fully
          indemnify each of the Finance Parties from and against any expense,
          loss, damage or liability which they may incur as a consequence of any
          failure to pay any sum due pursuant to the Finance Documents when due,
          or any failure to borrow when obliged to do so in accordance with this
          Agreement (including without limitation failure to satisfy any
          conditions precedent to such borrowing) or repaying an Advance
          otherwise than on the last day of an


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          Interest Period or otherwise in connection with a breach by ChiRex
          Inc. or any member of the ChiRex Group of this Agreement or of any
          Finance Document, except where it is otherwise reimbursed by a member
          of the ChiRex Group under the Finance Documents. Without prejudice to
          its generality, the indemnity in the preceding sentence extends to any
          interest, fees or other sums whatsoever paid or payable on account of
          any funds borrowed in order to carry any amount which a member of the
          ChiRex Group fails to pay in breach of this Agreement and to any loss
          (including loss of profit), premium, penalty or expenses which may be
          incurred in liquidating or employing deposits from third parties
          acquired to make, maintain or fund outstanding Advances or any other
          amount due or to become due under this Agreement.

27.2      Currency Indemnity

          Without prejudice to Clause 27.1, if:-

27.2.1    any amount payable by any Obligor under or in connection with any
          Finance Document is received by any Finance Party in a currency (the
          "Payment Currency") other than that agreed in the relevant Finance
          Document (the "Agreed Currency"), whether as a result of any
          judgement, decree or order or the enforcement thereof, the liquidation
          of that member or otherwise; and

27.2.2    the amount produced by converting the Payment Currency so received
          into the Agreed Currency is less than the relevant amount of the
          Agreed Currency;

          then the relevant Obligor shall, as an independent obligation,
          indemnify the relevant Finance Party for the deficiency and any loss
          sustained as a result. Such conversion shall be made at such
          prevailing rate of exchange, on such date and in such market as is
          determined by the relevant Finance Party as being most appropriate for
          the conversion. The relevant Obligor shall in addition pay the costs
          of the conversion as an independent and joint and several obligation.

27.3      Waiver

          Each Obligor waives any right it may have in any jurisdiction to pay
          any amount under any Finance Document in a currency other than that in
          which it is expressed to be payable in the relevant Finance Document.

28.       CERTIFICATES CONCLUSIVE


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          A certificate, determination, notification or opinion of a Finance
          Party, the Majority Lenders or any Lender provided for in any Finance
          Document shall be conclusive save in the case of manifest error.

29.       GOVERNING LAW

          This Agreement shall be governed by and construed in accordance with
          the laws of England.

30.       JURISDICTION

30.1      Submission

          For the benefit of each Finance Party, each Obligor agrees that the
          courts of England shall have jurisdiction to settle any disputes in
          connection with any Finance Documents and accordingly submits to the
          jurisdiction of the English courts.

30.2      Service of Process

          Without prejudice to any other mode of service, each Obligor:-

          (a)       irrevocably appoints the Borrower as its agent for service
                    of process relating to any proceedings before the English
                    courts in connection with any Finance Document;

          (b)       agrees that failure by a process agent to notify it of the
                    process will not invalidate the proceedings concerned; and

          (c)       (without prejudice to other forms of service permitted by
                    law) consents to the service of process relating to any such
                    proceedings by prepaid posting of a copy of the process to
                    its address for notices to it from time to time under Clause
                    21 (Notices).

          (d)       The Borrower irrevocably accepts its appointment as agent
                    for service of process under the Finance Documents as set
                    forth in sub-clause (a).

30.3      Forum Convenience and Enforcement Abroad

          Each Obligor:-


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          (a)       waives objection to the English courts on grounds of
                    inconvenient forum or otherwise as regards proceedings in
                    connection with a Finance Document; and

          (b)       agrees that a judgement, decree or order of an English court
                    or other court in connection with a Finance Document is
                    (subject to rights of appeal before the English courts or
                    such other courts) conclusive and binding on it and may be
                    enforced against it in the courts of any other jurisdiction.

30.4      Non-Exclusivity

          Nothing in this Clause 30 limits the right of a Finance Party to bring
          proceedings against any Obligor in connection with any Finance
          Document:-

          (a)       in any other court of competent jurisdiction; or

          (b)       concurrently in more than one jurisdiction.

31.       COUNTERPARTS

          This Agreement may be executed in any number of counterparts and all
          of such counterparts taken together shall be deemed to constitute one
          and the same instrument.

                  [Remainder of page intentionally left blank]


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CHIREX (HOLDINGS) LIMITED, in its capacity as the Borrower


By: /s/ Michael A. Griffith
   -----------------------------------

Print Name: Michael A. Griffith
           ---------------------------

Title: Chief Financial Officer
      --------------------------------

CHIREX INC., in its capacity as a Guarantor


By: /s/ Michael A. Griffith
   -----------------------------------

Print Name: Michael A. Griffith
           ---------------------------

Title: Chief Financial Officer
      --------------------------------

CHIREX (DUDLEY) LIMITED, in its capacity as a Guarantor


By: /s/ Michael A. Griffith
   -----------------------------------

Print Name: Michael A. Griffith
           ---------------------------

Title: Chief Financial Officer
      --------------------------------

CHIREX (ANNAN) LIMITED, in its capacity as a Guarantor


By: /s/ Michael A. Griffith
   -----------------------------------

Print Name: Michael A. Griffith
           ---------------------------

Title: Chief Financial Officer
      --------------------------------


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BANKERS TRUST INTERNATIONAL PLC, in its capacity as a Joint
Arranger


By: /s/ Elene A. Harkavy
   -----------------------------------

Print Name: Elene A. Harkavy
           ---------------------------

Title: Vice President
      --------------------------------

MIDLAND BANK PLC, in its capacity as a Joint Arranger and a
Lender


By: /s/ Keith Taylor
   -----------------------------------

Print Name: Keith Taylor
           ---------------------------

Title: Senior Business Banking Manager
      --------------------------------

BANKERS TRUST COMPANY, in its capacities as a Lender, Agent and
Security Agent


By: /s/ Elene A. Harkavy
   -----------------------------------

Print Name: Elene A. Harkavy
           ---------------------------

Title: Vice President
      --------------------------------


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                                   SCHEDULE 1

                         Commitments and Lending Offices
                         -------------------------------

           Names and Addresses of
                     Initial Lenders                               Commitment
           ------------------------------------------------------------------
                                                                    GBP

           BANKERS TRUST COMPANY                                   31,000,000
           1 Appold Street
           London EC2A 1HE

           Attn.                                             Barry  Jefferies
           Tel:     +44 171 982 2500
           Fax:     +44 171 982 2271

           MIDLAND BANK PLC                                        31,000,000
           50 Grey Street
           Newcastle upon Tyne
           NE99 1SA

           Attn.                                                 Keith Taylor
           Tel:     +44 191 220 6127
           Fax:     +44 191 220 6197


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                                   SCHEDULE 2

                               Repayment Schedule
                               ------------------

                                                           Scheduled Repayment
           Repayment Date                                    of Term Loans
           ---------------------- --------------------------------------------
                                                                 GBP

           31st December, 1998                                4,444,444.44
           30th June, 1999                                    4,444,444.44
           31st December, 1999                                4,444,444.44
           30th June, 2000                                    4,444,444.44
           31st December, 2000                                4,444,444.44
           30th June, 2001                                    4,444,444.44
           31st December, 2001                                4,444,444.44
           30th June, 2002                                    4,444,444.44
           31st December, 2002                                4,444,444.48


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                                   SCHEDULE 3

                            Form of Drawdown Request

To: [Insert details of Agent's administrations department]

Attn:
         [            ]

GBP 62,000,000 facilities agreement dated [
   ], 1997

We refer to the above agreement between, inter alia, ourselves, the Arrangers,
the Lenders described therein and yourselves as Agent (as heretofore amended,
the "Facilities Agreement", which expression includes any amendments or
supplements thereto or restatements thereof). Terms defined in the Facilities
Agreement have the same meaning in this notice.

Pursuant to Clause 5.1 of the Facilities Agreement, we hereby give you notice of
the following proposed drawing of an Advance under the [Tranche A Term Facility]
[Tranche B Multicurrency Revolving Facility]:

(a)       Proposed Drawdown Date (a Business Day):

(b)       Currency [GBP only if Tranche A Facility; USD, DEM, FF LIT, CHF, Yen
          and GBP if Tranche B Facility]:

(c)       Amount:

(d)       Duration of first Interest Period:

(e)       Payment instructions:

(f)       Purpose:

We confirm that no Event of Default or Potential Event of Default has occurred
and is continuing unremedied or unwaived or will occur as a result of making
this Advance and that each of the representations and warranties required to be
made in accordance with Clause 12 of the Facilities Agreement is true and
accurate on the date hereof.

Dated: _____________


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[BORROWER]


By:
   ---------------------------

Its:
    --------------------------

Notes

(1)       No more than fifteen separate Tranche B Revolving Advances may be
          outstanding at any one time.

(2)       Currencies other than USD, DEM, FF, LIT, CHF, Yen and GBP may not be
          requested unless the Agent has confirmed in writing to the Borrower
          that such other currency is freely available to all the Lenders and is
          one in which dealings regularly occur in the London interbank market.

(3)       These notes are included for convenience only and are to be ignored in
          construing the Facilities Agreement.


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                                   SCHEDULE 4

                            Structure of ChiRex Group

                                [GRAPHIC OMITTED]


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                                   SCHEDULE 5

                 Calculation of the Mandatory Liquid Asset Costs
                            for any Sterling Advances

(a)       The Mandatory Liquid Asset Costs for an Advance if denominated in GBP
          for each Interest Period for that Advance is calculated in accordance
          with the following formula:

                  BY + L(Y-X) + S(Y-Z)
                  -------------------
          % PER ANNUM
                          100 - (B+S)

          where on the day of the application of the formula:

          B         is the percentage of the Agent's eligible liabilities which
                    the Bank of England then requires the Agent to hold on a
                    non-interest-bearing deposit account in accordance with its
                    cash ratio requirements;

          Y         is the rate at which GBP deposits are offered by the Agent
                    to leading banks in the London interbank market at or about
                    11.00 a.m. on that day for the relevant period;

          L         is the percentage of eligible liabilities which (as a result
                    of the requirements of the Bank of England) the Agent
                    maintains as secured money with members of the London
                    Discount Market Association or in certain marketable or
                    callable securities approved by the Bank of England, which
                    percentage shall (in the absence of evidence that any other
                    figure is appropriate) be conclusively presumed to be 5 per
                    cent.;

          X         is the rate at which secured GBP deposits may be placed by
                    the Agent with members of the London Discount Market
                    Association at or about 11.00 a.m. on that day for


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                    the relevant period or, if greater, the rate at which GBP
                    bills of exchange (of a tenor equal to the duration of the
                    relevant period) eligible for rediscounting at the Bank of
                    England can be discounted in the London Discount Market at
                    or about 11.00 a.m. on that day;

          S         is the percentage for the Agent's eligible liabilities which
                    the Bank of England requires the Agent to place as a special
                    deposit; and

          Z         is the interest rate per annum allowed by the Bank of
                    England on special deposits.

(b)       For the purposes of this Schedule:

          (i)       "eligible liabilities" and "special deposits" have the
                    meanings given to them at the time of application of the
                    formula by the Bank of England; and

          (ii)      "relevant period" in relation to each Interest Period means:

                    (A)       if it is 3 months or less, that Interest Period or

                    (B)       if it is more than 3 months, 3 months.

(c)       In the application of the formula, B, Y, L, X, S and Z are included in
          the formula as figures and not as percentages, e.g. if B=0.5% and Y =
          15%, BY would be calculated as 0.5 x 15.

(d)       The formula is applied on the first day of each relevant period. Each
          amount is rounded up to the nearest one- sixteenth of one per cent.

(e)       If the Agent determines that a change in circumstances has rendered,
          or will render, the formula inappropriate, the Agent (after
          consultation with the Lenders) shall notify the Borrower of the manner
          in which the Mandatory Liquid Asset Costs for such


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          Advances will subsequently be calculated. The manner of calculation so
          notified by the Agent shall, in the absence of manifest error, be 
          binding on all the Obligors.


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                                   SCHEDULE 6

                            Form of Deed of Accession

THIS DEED is made this [ ] day of __________, by [ ], as Guarantor, IN FAVOUR
OF:

(1)       CHIREX (HOLDINGS) LIMITED (the "Borrower")

(2)       BANKERS TRUST INTERNATIONAL PLC AND MIDLAND BANK PLC as Joint
          Arrangers;

(3)       BANKERS TRUST COMPANY, as Agent (the "Agent");

(4)       BANKERS TRUST COMPANY, as Security Agent;

(5)       THE LENDERS PARTY TO THE FACILITIES AGREEMENT DESCRIBED BELOW; and

(6)       THE OBLIGORS PARTY TO THE FACILITIES AGREEMENT DESCRIBED BELOW.

WHEREAS:

(A)       This Deed is supplemental to a facilities agreement (the "Facilities
          Agreement", which expression includes any amendments or supplements
          thereto or restatements thereof) dated __ October, 1997 made among the
          parties referred to in paragraphs (1) to (6) above.

(B)       [insert name of party] wishes to accede to the Facilities Agreement as
          a Guarantor.

NOW THIS DEED WITNESSETH AS FOLLOWS:

(1)       Words and expressions defined in the Facilities Agreement shall have
          the same meanings when used herein.

(2)       [insert name of Guarantor] hereby:

          (a)       agrees to be bound by all the terms and conditions of the
                    Facilities Agreement insofar as they relate to a Guarantor
                    (including without limitation Clause 15 (Guarantee) and
                    Clause 30 (Jurisdiction) of the


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                    Facilities Agreement) as if it were a party to the
                    Facilities Agreement in such capacity; and

          (b)       represents and warrants to the Agent and the other Finance
                    Parties in the terms of the Facilities Agreement

(3)       The undersigned Guarantor agrees to be bound by all the terms and
          conditions of the Facilities Agreement insofar as they relate to an
          Obligor as if it were a party to the Facilities Agreement in such
          capacity.

(4)       [The foregoing notwithstanding, the obligations of the undersigned
          Guarantors under the foregoing shall be limited as follows:

          [limitations to guarantees, if not already in Facilities Agreement, to
          the extent required by applicable law]

(5)       The undersigned Guarantor confirms that its address for the purposes
          of Clause 21 (Notices) of the Facilities Agreement is set out under
          its name as follows:

          [Name]
          [Address]

          Attention:                             [
          ]
          Facsimile:                             [
          ]

(6)       Each of the undersigned hereby agrees that [insert name of Guarantor]
          shall, from the date of the later of (i) the execution by Agent of
          this Deed and (ii) the execution by Borrower of this Deed, accede to
          the Facilities Agreement as if it were a Guarantor and an Obligor
          named therein and a party thereto.

(7)       This Deed may be executed in any number of counterparts and all of
          such counterparts taken together shall be deemed to constitute one and
          the same instrument.

(8)       This Deed shall be governed by and construed in accordance with the
          laws of England.


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IN WITNESS WHEREOF the undersigned have caused this Deed to be duly executed and
delivered the day and year first above written.

EXECUTED and DELIVERED                      )
as a deed                                   )
for and on behalf of                        )
[                ]                          )
by                                          )
in the presence of                          )

EXECUTED and DELIVERED                      )
as a deed                                   )
for and on behalf of                        )
[             ]                             )
as Borrower                                 )
by [             ]                          )
in the presence of:                         )

SIGNED by
for and on behalf of
BANKERS TRUST COMPANY,
as Agent

 .............................................
Date:


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                                   SCHEDULE 7

                          Form of Transfer Certificate

[Note: the Transferor and Transferee should ensure that all regulatory
requirements (in particular compliance with the Financial Services Act of 1986
and any regulations made thereunder) are satisfied in connection with their
entry into of their Transfer Certificate.]

TRANSFER CERTIFICATE

To:       [name of Agent]
          for and on behalf of the Borrower, the other Obligors, the
          Lenders and the other Finance Parties (each as defined in the
          Facility Agreement referred to below).

From:     [insert name of Transferor] (the "Transferor")

          [insert name of Transferee] (the "Transferee")

This transfer certificate (this "Certificate") relates to a Facilities Agreement
dated [ ] 1997, and made among Bankers Trust Company, as Agent and the Lenders
and Arrangers, described therein (the "Facilities Agreement", which expression
includes any amendments or supplements thereto or restatements thereof). Terms
defined in the Facilities Agreement shall, unless otherwise defined in this
Certificate, have the same meanings when used in this Certificate.

(1)       The Transferor by its execution of this Certificate:-

          (a)       confirms that the details which appear in column II of the
                    First Schedule of this Certificate accurately state,
                    respectively, the amount of the Transferor's Commitment and
                    the Transferor's participation in Advances as at the date of
                    this Certificate;

          (b)       requests the Transferee to accept and procure, in accordance
                    with Clause [24.3] of the Facilities Agreement, transfer to
                    the Transferee of the portion of the Transferor's
                    participation in the Facility specified in column III of the
                    First Schedule of this Certificate by counter-signing


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                    this Certificate and delivering it to the Agent at its
                    address for the giving of notices under the Facility
                    Agreement so as to take effect on the date specified in the
                    Second Schedule of this Certificate (the "Transfer Date").

(2)       The Transferee by its execution of this Certificate requests the
          Obligors, the Lenders, the Agent and the other Finance Parties to
          accept this Certificate as being delivered under and for the purposes
          of Clause [25.3] of the Facilities Agreement so as to take effect in
          accordance with the terms of that Clause on the Transfer Date.

(3)       The Transferee undertakes to pay to the Agent for the Agent's own
          account a transfer fee of [USD ________] as provided in Clause
          [25.3.2(d)] of the Facility Agreement.

(4)       The Transferee hereby:

          (a)       confirms that it has received from the Transferor a copy of
                    the Facilities Agreement together with such other documents
                    and information as it has requested in connection with this
                    transaction;

          (b)       confirms that it has not relied, and will not hereafter
                    rely, on the Transferor or any other Finance Party to the
                    Facilities Agreement or any of the other Finance Documents
                    to check or enquire on its behalf into the legality,
                    validity, effectiveness, adequacy, accuracy or completeness
                    of any such documents or information;

          (c)       agrees that it has not relied, and will not hereafter rely,
                    on the Transferor or any other Finance Party to the
                    Facilities Agreement or any of the other Finance Documents
                    to assess or keep under review on its behalf the financial
                    condition, creditworthiness, condition, affairs, status or
                    nature of the Borrower, the other Obligors or any other
                    party to the Facilities Agreement or the other Finance
                    Documents; and


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          (d)       represents and warrants to the Transferor and all other
                    parties to the Facilities Agreement that it (i) has power to
                    become a party to the Facilities Agreement as a "Lender" on
                    the terms herein and therein set out, and (ii) has taken all
                    necessary steps to authorise execution and delivery of this
                    Certificate.

(5)       Neither the Transferor nor any other Finance Party to the Facilities
          Agreement makes any representation or warranty nor assumes any
          responsibility with respect to the legality, validity, effectiveness,
          adequacy or enforceability of the Finance Documents and assumes no
          responsibility for the financial condition of the Borrower, the other
          Obligors or any other party to the Finance Documents or for the
          performance and observance by the Borrower or any other Obligor of any
          of its obligations under the Finance Documents and any and all such
          representations and warranties and responsibility, whether express or
          implied by law or otherwise, are hereby excluded.

(6)       On execution of this Certificate by the Agent for itself and on behalf
          of the Obligors, the Lenders (other than the Transferor) and the other
          Finance Parties, each of them accepts the Transferee on and with
          effect from the Transfer Date as a party in substitution for the
          Transferor with respect to all those rights and obligations which by
          the terms of the Facilities Agreement, the other Finance Documents and
          this Certificate are assumed by the Transferor.

(7)       By its execution hereof, the Transferee confirms the appointment of
          [insert name of Agent] to act as its agent under and in connection
          with the Finance Documents and irrevocably authorises the Agent and
          for and on its behalf to exercise such rights, powers and discretions
          as are delegated to it by the terms of the Finance Documents, together
          with all such rights, powers and discretions as are incidental
          thereto, and to give a good discharge for any moneys payable under the
          Finance Documents.

(8)       This Certificate and the rights and obligations of the parties hereto
          shall be governed by and construed in accordance with English law.


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AS WITNESS the hands of authorised signatories for and on behalf of the
Transferor, the Transferee and the Agent on the respective dates appearing
below.


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                   First Schedule to the Transfer Certificate


         I                         II                            III
 Facility Details          Transferor Position              Position to be
  to Transferee             Prior to Transfer                Transferred


[                 ]       [                   ]          [                   ]
[                 ]       [                   ]          [                   ]
[                 ]       [                   ]          [                   ]
[                 ]       [                   ]          [                   ]


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                   Second Schedule to the Transfer Certificate

Particulars relating to the Transferee

Transfer Date                  :
Lending Office                 :
Contact Name                   :
Account for Payments
                               :
Telephone                      :
Facsimile                      :

[Transferor]                                                   [Transferee]


By:..............................

By:..............................

Date: [                     ]                                  Date: [         ]


[Agent]

By:..............................


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                                   SCHEDULE 8

                             Continuing Indebtedness

                                      NONE

                                                                   Executed Copy