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                                                                    EXHIBIT 23.3
 
               CONSENT OF ERNST & YOUNG ENTREPRENEURS' DEPARTMENT
 
                  D'ERNST & YOUNG AUDIT, INDEPENDENT AUDITORS
 
     We consent to the reference to our firm under the caption "Experts" in the
Registration Statement (Form S-3) and related Prospectus of Integrated Surgical
Systems, Inc. for the registration of 619,355 shares of its common stock and to
the incorporation by reference therein of our reports dated September 10, 1997,
with respect to the consolidated financial statements of Innovative Medical
Machines International S.A. included in the Current Report (Form 8-K) dated
September 5, 1997, as amended, of Integrated Surgical Systems, Inc., and
included in the Registration Statement (Form SB-2 No. 333-31481) and related
Prospectus of Integrated Surgical Systems, Inc. dated November 14, 1997 filed
with the Securities and Exchange Commission.
 
                                                   ERNST & YOUNG ENTREPRENEURS
 
                                                   DEPARTMENT D'ERNST & YOUNG
                                                   AUDIT
                                                   Marc Bonhomme
                                                   Partner
 
Villeurbanne, France
 
December 10, 1997