1 Exhibit 3.1 CANADA BUSINESS CORPORATIONS ACT FORM 1 ARTICLES OF INCORPORATION (SECTION 6) 1 - NAME OF CORPORATION CliniChem Development Inc. 2 - THE PLACE IN CANADA WHERE THE REGISTERED OFFICE IS TO BE SITUATED Metropolitan Region of Montreal, Province of Quebec. 3 - THE CLASSES AND ANY MAXIMUM NUMBER OF SHARES THAT THE CORPORATION IS AUTHORIZED TO ISSUE An unlimited number of common shares. THE COMMON SHARES SHALL HAVE ATTACHED THERETO THE FOLLOWING RIGHTS, PRIVILEGES, RESTRICTIONS AND CONDITIONS: 1 - Each common share shall entitle the holder thereof to one (1) vote at all meetings of the shareholders of the Corporation. 2 - The holders of the common shares shall be entitled to receive during each year, as and when declared by the board of directors, dividends payable in money, property or by the issue of fully paid shares of the capital of the Corporation. 3 - In the event of the liquidation, dissolution or winding-up of the Corporation, whether voluntary or involuntary, or other distribution of assets of the Corporation among shareholders for the purpose of winding-up its affairs, the holders of the common shares shall be entitled to receive the remaining property of the Corporation. 4 - RESTRICTIONS, IF ANY, ON SHARE TRANSFERS No share in the share capital of the Corporation shall be transferred nor shall it be assigned without the approval of the directors certified by a resolution of the board of directors. 5 - NUMBER (OR MINIMUM AND MAXIMUM NUMBER) OF DIRECTORS A minimum of one (1) director and a maximum of fifteen (15) directors. 6 - RESTRICTIONS, IF ANY, ON BUSINESS THE CORPORATION MAY CARRY ON None. 7 - OTHER PROVISIONS, IF ANY (1) The number of the shareholders of the Corporation is limited to fifty (50), exclusive of present or former employees of the Corporation or of a subsidiary of the Corporation, two (2) or more persons holding one (1) or more shares jointly being counted as a single shareholder; (2) any distribution of securities to the public or invitation to the public to subscribe for the Corporation's securities is prohibited; and (3) the directors may appoint one or more directors, who shall hold office for a term expiring no later than the close of the next annual meeting of shareholders, but the total number of directors so appointed may not exceed one third ( ) of the number of directors elected at the previous annual meeting of shareholders. 8 - INCORPORATORS Name Address Jean Marc Huot 1155 Rene-Levesque Boulevard West 40th Floor Montreal, Quebec H3B 3V2 DATE SIGNATURE January 30, 1998 _____________________ Jean Marc Huot TITLE Incorporator ____________________________________________________________________________ FOR DEPARTMENTAL USE ONLY Corporation No. Filed 2 CANADA BUSINESS CORPORATIONS ACT FORM 3 NOTICE OF REGISTERED OFFICE OR NOTICE OF CHANGE OF REGISTERED OFFICE (SECTION 19) 1 - NAME OF CORPORATION CliniChem Development Inc. 2 - CORPORATION NO. 3 - PLACE IN CANADA WHERE THE REGISTERED OFFICE IS SITUATED Metropolitan Region of Montreal, Province of Quebec. 4 - ADDRESS OF THE REGISTERED OFFICE 275 Armand-Frappier Boulevard Laval, Quebec H7V 4A7 5 - EFFECTIVE DATE OF CHANGE Not applicable. 6 - PREVIOUS ADDRESS OF THE REGISTERED OFFICE Not applicable. DATE SIGNATURE ______________________________ January 30, 1998 Jean Marc Huot TITLE Incorporator ________________________________________________________________________________ Filed 3 CANADA BUSINESS CORPORATIONS ACT FORM 6 NOTICE OF DIRECTORS OR NOTICE OF CHANGE OF DIRECTORS (SECTIONS 106 AND 113) 1 - NAME OF CORPORATION CliniChem Development Inc. 2 - CORPORATION NO. 3 - THE FOLLOWING PERSONS BECAME DIRECTORS OF THIS CORPORATION Effective date: Not applicable. Name Residential address OCCUPATION Resident Canadian - Y/N 4 - THE FOLLOWING PERSONS CEASED TO BE DIRECTORS OF THIS CORPORATION Effective date: Not applicable. Name Residential address 5 - THE DIRECTORS OF THIS CORPORATION NOW ARE Name Jean Marc Huot Residential address 11 Douglas Avenue Westmount, Quebec H3Y 1V5 OCCUPATION Lawyer Resident Canadian - Y/N Y DATE SIGNATURE January 30, 1998 ___________________________________ Jean Marc Huot TITLE Incorporator _______________________________________________________________________________ Filed