1 Exhibit 99.2 OSI PHARMACEUTICALS, INC. AND SUBSIDIARIES Unaudited Pro Forma Condensed Combined Balance Sheet As of June 30, 1999 (In thousands) Pro Forma Adjustments Historical ------------------------------ ---------------------- Assets Not OSI Cadus Acquired and Pro Forma June 30, June 30, Liabilities Other June 30, Assets 1999 1999 Not Assumed (1) Adjustments 1999 --------- --------- --------------- ----------- --------- Current assets: Cash and cash equivalents $ 10,498 6,978 (6,978) (2,274)(2) 8,224 Restricted cash -- 296 (296) - Short-term investments 10,590 -- 10,590 Receivables, including trade receivables 2,301 -- 2,301 Interest receivables 142 -- 142 Grants receivable 235 -- 235 Prepaid expenses and other current assets 890 215 (141) 964 ---------------------------------------------------------------------- Total current assets 24,656 7,489 (7,415) (2,274) 22,456 ---------------------------------------------------------------------- Restricted cash - noncurrent -- 18,641 (18,641) - Property, equipment and leasehold improvements -- net 7,500 2,439 (144) (1,265)(6) 8,530 Compound library assets -- net 4,314 -- 1,000 (3) 4,764 (550)(6) Investments in other ventures -- 1,653 (1,653) - Intangible assets -- net -- -- 225 (4) 6,728 (125)(6) Other assets -- net 1,351 1,437 (1,217) (120)(6) 1,451 ---------------------------------------------------------------------- Total assets $ 44,449 31,659 (29,070) (3,109) 43,929 ====================================================================== Liabilities and Stockholders' Equity Current liabilities: Accounts payable and accrued expenses $ 3,606 1,484 (1,334) 3,756 Unearned revenue -- current 982 -- 982 Loans payable -- current 167 304 (304) 167 ---------------------------------------------------------------------- Total current liabilities 4,755 1,788 (1,638) 4,905 ---------------------------------------------------------------------- Unearned revenue -- long term 429 -- 429 Loans payable -- long term 319 -- 319 Deferred acquisition costs 701 -- 701 Accrued postretirement benefits cost 1,499 -- 1,499 Reserve for litigation damages -- 18,641 (18,641) - Stockholders' equity: Preferred Stock -- -- -- Common stock 224 132 (132) 224 Additional paid-in capital 105,050 59,689 (59,689) 105,050 Accumulated deficit (62,203) (48,291) 48,291 (670)(5) (62,873) Accumulated other comprehensive loss (267) -- (267) Treasury stock (6,058) (300) 300 (6,058) ---------------------------------------------------------------------- Total stockholders' equity 36,746 11,230 (11,230) (670) 36,076 ---------------------------------------------------------------------- Total liabilities and stockholders' equity $ 44,449 31,659 (31,509) (670) 43,929 ====================================================================== 2 OSI PHARMACEUTICALS, INC. AND SUBSIDIARIES Unaudited Pro Forma Condensed Combined Statement of Operations For the nine months ended June 30, 1999 (In thousands) Pro Forma Adjustments Historical ---------------------------- -------------------- Revenue and OSI Cadus Expenses of Pro Forma June 30, June 30, Activities Other June 30, 1999 1999 Not Assumed (7) Adjustments 1999 -------- -------- --------------- ----------- --------- Revenues: Collaborative program revenues $ 12,600 7,704 (5,679) 14,625 Other research revenue 814 -- 814 License revenue 2,171 -- 2,171 Sales 916 -- 916 -------------------------------------------------------------------- 16,501 7,704 (5,679) 18,526 -------------------------------------------------------------------- Expenses: Research and development costs 14,766 11,588 (5,727) 70 (8) 20,697 Production and service costs 1,239 -- 1,239 Selling, general and administrative 6,364 5,702 (5,157) 6,909 Amortization of intangibles 1,096 -- 30 (8) 1,126 -------------------------------------------------------------------- 23,465 17,290 (10,884) 100 29,971 -------------------------------------------------------------------- Loss from operations (6,964) (9,586) 5,205 (100) (11,445) Other income (expense): Net investment income 658 811 (811) (85)(9) 573 Loss of equity in other ventures - (974) 974 - Reserve for litigation damages - (18,500) 18,500 - Other expense -- net (54) 45 (45) (54) -------------------------------------------------------------------- Net loss $ (6,360) (28,204) 23,823 (185) (10,926) ==================================================================== Weighted average number of shares of common stock outstanding 21,430 21,430 ======== ======== Basic and diluted loss per weighted average share of common stock outstanding $ (0.30) (0.51) ======== ======== 3 OSI PHARMACEUTICALS, INC. AND SUBSIDIARIES Unaudited Pro Forma Condensed Combined Statement of Operations For the year ended September 30, 1998 (In thousands) Pro Forma Adjustments Historical ---------------------------- -------------------- Revenue and OSI Cadus Expenses of Pro Forma Sept 30, Dec. 31, Activities Other Sept 30, 1998 1998 Not Assumed (7) Adjustments 1998 -------- -------- --------------- ----------- --------- Revenues: Collaborative program revenues $ 16,166 12,576 (9,876) 18,866 Other research revenue 1,429 - 1,429 License revenue 752 - 752 Sales 1,121 - 1,121 -------------------------------------------------------------------- 19,468 12,576 (9,876) 22,168 -------------------------------------------------------------------- Expenses: Research and development costs 20,350 15,389 (7,565) 28,264 90 (8) Production and service costs 955 - 955 Selling, general and administrative 8,077 8,977 (8,078) 8,976 Amortization of intangibles 1,461 - 40 (8) 1,501 -------------------------------------------------------------------- 30,843 24,366 (15,643) 130 39,696 -------------------------------------------------------------------- -------------------------------------------------------------------- Loss from operations (11,375) (11,790) 5,767 (130) (17,528) -------------------------------------------------------------------- Other income (expense): Net investment income 1,468 1,834 (1,834) (115)(9) 1,353 Loss of equity in other ventures - (1,144) 1,144 - Reserve for litigation damages - (18,500) 18,500 - Other expense - net (277) (90) 90 (277) -------------------------------------------------------------------- Net loss $(10,184) (29,690) 23,667 (245) (16,452) ==================================================================== Weighted average number of shares of common stock outstanding 21,373 21,373 ======== ======== Basic and diluted loss per weighted average share of common stock outstanding $ (0.48) (0.77) ======== ======== 4 NOTES TO THE UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS (IN THOUSANDS) (1) Book values of assets not acquired and liabilities not assumed by OSI Pharmaceuticals, Inc. ("OSI") from Cadus Pharmaceutical Corporation ("Cadus") in accordance with the Asset Purchase Agreement dated July 30, 1999 by and between OSI and Cadus (the "Agreement"). The book values of the assets acquired and the liabilities assumed by OSI from Cadus are summarized as follows: Fixed assets $ 2,295 Prepaid expenses 74 Patent costs 220 -------- $ 2,589 ======== Employee benefits liability $ 150 ======== (2) Cash paid by OSI in connection with the Agreement summarized as follows: Purchase price to Cadus $ 1,574 Professional fees 700 -------- $ 2,274 ======== In addition, OSI assumed $150 of certain employee-related liabilities resulting in a total acquisition cost of $2,424. (3) Allocation of the purchase price to compound library acquired by OSI (see note 5 regarding valuation study). (4) Allocation of the purchase price to the assembled workforce intangible (see note 5 regarding valuation study). (5) Represents an estimated charge of $670 for acquired in-process research and development costs, net of negative goodwill allocation (see note 6). No tax benefit has been reflected in connection with this charge in recognition of the uncertainty that any such tax benefits will be realized by OSI based on its history of operating losses since OSI's inception. OSI has engaged a professional services firm to conduct a valuation study of the assets acquired under the Agreement, including a determination of acquired in-process research and development costs. This valuation has not yet been completed. As a result, the allocation of the purchase price is subject to change upon completion of the valuation study, including the estimated amount of acquired in-process research and development costs. The estimated charge of $670 for acquired in-process research and development costs has been reflected as a reduction of stockholders' equity in the pro forma condensed combined balance sheet as of June 30, 1999. 5 This same charge has been excluded from the pro forma condensed combined statement of operations for the year ended September 30, 1998 since the charge is non-recurring and directly related to the Agreement. (6) Allocation of negative goodwill to reduce noncurrent financial assets on a pro rata basis. The determination of negative goodwill and the allocation to noncurrent financial assets are summarized as follows: Summary of fair value of assets acquired: Fixed assets $ 2,295 Patents 220 Prepaid expenses 74 Assembled work force 225 Compound library 1,000 In-process research and development costs 1,500 ------- Total fair value of assets acquired 5,314 Purchase price 2,424 ------- Negative goodwill $ 2,890 ======= Pro rata allocation of negative goodwill: Fixed assets $ 1,265 Patents 120 Assembled work force 125 Compound library 550 In-process research and development costs 830 ------- Negative goodwill $ 2,890 ======= Summary of fair value of assets acquired, net of the allocation of negative goodwill: Fixed assets $ 1,030 Patents 100 Prepaid expenses 74 Assembled work force 100 Compound library 450 In-process research and development costs 670 ------- Fair value of assets acquired, net $ 2,424 ======= 6 (7) Revenues and expenses of activities not assumed by OSI. In accordance with the Agreement, OSI assumed the operations of Cadus' facility, including lease obligations for the facility and certain research equipment, 47 research employees and the research program with Solvay Pharmaceuticals B.V. The determination of the pro forma employee-related expenses is based on the ratio of research employees hired by OSI to the total number of Cadus research employees during the pro forma periods. Other research costs and administrative expenses were estimated based on the operating activities assumed by OSI as a result of the Agreement. No provision for income taxes has been made based on the history of the operating losses of both OSI and Cadus since their inceptions. A summary of revenue and expenses activity acquired by OSI is as follows: Year Ended Nine Months Ended Sept. 30, 1998 Jun. 30, 1999 -------------- ----------------- Research revenue (Solvay) 2,700 2,025 Research costs (47 employees) including payroll and direct research costs (7,824) (5,861) Administrative expenses (899) (545) ------ ------ Net loss (6,023) (4,381) ====== ====== (8) Represents the amortization expense of the compound library (recorded in research and development costs), patents and workforce intangibles (recorded in amortization of intangibles) acquired under the Agreement based on the straight-line method over five years. (9) Represents the reduction of investment income based on the total payments of $2,274 assuming an average rate of return of 5% per annum based on OSI's historical investment performance.