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SEC 1344
(10-2002)      PERSONS WHO POTENTIALLY ARE TO RESPOND TO THE COLLECTION OF
Previous       INFORMATION CONTAINED IN THIS FORM ARE NOT REQUIRED TO
versions       RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB
obsolete       CONTROL NUMBER.

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                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                   FORM 12B-25

                           NOTIFICATION OF LATE FILING

                             SEC FILE NUMBER 0-33393
                             CUSIP NUMBER 66737P105


One):  [X] Form 10-K  [ ]Form 20-F  [ ]Form 11-K  [ ]Form 10-Q

[ ]Form N-SAR
For Period Ended:  December 31, 2003
[ ] Transition Report on Form 10-K
[ ] Transition Report on Form 20-F
[ ] Transition Report on Form 11-K
[ ] Transition Report on Form 10-Q
[ ] Transition Report on Form N-SAR

For the Transition Period Ended: ___________________

  Read Instruction (on back page) Before Preparing Form. Please Print or Type.

    NOTHING IN THIS FORM SHALL BE CONSTRUED TO IMPLY THAT THE COMMISSION HAS
                   VERIFIED ANY INFORMATION CONTAINED HEREIN.

If the notification relates to a portion of the filing checked above, identify
the Item(s) to which the notification relates:

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PART I -- REGISTRANT INFORMATION

    Northwest Biotherapeutics, Inc.
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Full Name of Registrant

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Former Name if Applicable

    22322  20th Avenue SE, Suite 150
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Address of Principal Executive Office (Street and Number)

    Bothell, WA  98021
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City, State and Zip Code

PART II -- RULES 12B-25(B) AND (C)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

            (a) The reasons described in reasonable detail in Part III of this
            form could not be eliminated without unreasonable effort or expense;
            (b) The subject annual report, semi-annual report, transition report
            on Form 10-K, Form 20-F,11-K or Form N-SAR, or portion thereof, will
[X]         be filed on or before the fifteenth calendar day following the
            prescribed due date; or the subject quarterly report or transition
            report on Form 10-Q, or portion thereof will be filed on or before
            the fifth calendar day following the prescribed due date; and
            (c) The accountant's statement or other exhibit required by Rule
            12b-25(c) has been attached if applicable.

PART III -- NARRATIVE

State below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q,
N-SAR, or the transition report portion thereof, could not be filed within the
prescribed time period.

      As reported in the Registrant's Quarterly Report on Form 10-Q for the
      period ended September 30, 2003, filed with the Commission on November 14,
      2003, the Registrant is exploring various strategic alternatives for the
      long-term capital requirements of the Company, including raising financing
      to fund continued operations.

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      The outcome of these matters will affect the content of the Registrant's
      disclosures regarding its liquidity, capital resources and continued
      operations, as well as other significant disclosures required in the
      Annual Report on Form 10-K. In addition, these matters have required
      management to devote substantially all of its time and attention to these
      issues for the past several months. These factors have resulted in the
      Registrant's inability to complete and file its Annual Report or Form 10-K
      by March 30, 2004 and could not have been eliminated without unreasonable
      effort or expense.

PART IV-- OTHER INFORMATION

(1) Name and telephone number of person to contact in regard to this
notification

    Alton L. Boynton                        425                   608-3000
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       (Name)                           (Area Code)           (Telephone Number)

(2) Have all other periodic reports required under Section 13 or 15(d) of the
Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of
1940 during the preceding 12 months or for such shorter period that the
registrant was required to file such report(s) been filed? If answer is no,
identify report(s). [X]Yes [ ]No

(3) Is it anticipated that any significant change in results of operations from
the corresponding period for the last fiscal year will be reflected by the
earnings statements to be included in the subject report or portion thereof?
[ ]Yes [X]No If so, attach an explanation of the anticipated change, both
narratively and quantitatively, and, if appropriate, state the reasons why a
reasonable estimate of the results cannot be made.

                         Northwest Biotherapeutics, Inc.
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                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.

Date    March 31, 2004             By  /s/ Alton L. Boynton
     --------------------              -----------------------------------------
                                       Alton L. Boynton, President

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INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly authorized representative. The name and title of the person
signing the form shall be typed or printed beneath the signature. If the
statement is signed on behalf of the registrant by an authorized representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

                                    ATTENTION

INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL CRIMINAL
VIOLATIONS (SEE 18 U.S.C. 1001).

GENERAL INSTRUCTIONS

1. This form is required by Rule 12b-25 (17 CFR 240.12b-25) of the General Rules
and Regulations under the Securities Exchange Act of 1934.

2. One signed original and four conformed copies of this form and amendments
thereto must be completed and filed with the Securities and Exchange Commission,
Washington, D.C. 20549, in accordance with Rule 0-3 of the General Rules and
Regulations under the Act. The information contained in or filed with the form
will be made a matter of public record in the Commission files.

3. A manually signed copy of the form and amendments thereto shall be filed with
each national securities exchange on which any class of securities of the
registrant is registered.

4. Amendments to the notifications must also be filed on Form 12b-25 but need
not restate information that has been correctly furnished. The form shall be
clearly identified as an amended notification.

5. Electronic filers. This form shall not be used by electronic filers unable to
timely file a report solely due to electronic difficulties. Filers unable to
submit a report within the time period prescribed due to difficulties in
electronic filing should comply with either Rule 201 or Rule 202 of Regulation
S-T (Section 232.201 Or Section 232.202 of this chapter) or apply for an
adjustment in filing date pursuant to Rule 13(b) of Regulation S-T (Section
232.13(b) of this Chapter).

http://www.sec.gov/divisions/corpfin/forms/12b-25.htm
Last update: 10/21/2002




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