EXHIBIT 32.1

     CERTIFICATION PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

The undersigned hereby certify pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that this Quarterly
Report on Form 10-Q for the quarterly period ended March 31, 2006 ("Report")
fully complies with the requirements of Section 13(a) of the Securities Exchange
Act of 1934 and that information contained in this Report fairly presents, in
all material respects, the financial condition and results of operations of the
registrant.

                                 CNB CORPORATION
                                   (Registrant)

                                 By:  /s/ James C. Conboy, Jr.
                                     --------------------------------
                                      James C. Conboy, Jr.
                                      President and Chief Executive Officer

Date: May 11, 2006               By:  /s/ Shanna L. Hanley
                                     --------------------------------
                                      Shanna L. Hanley
                                      Treasurer
                                      (Chief Financial Officer)