EXHIBIT 10.2
                                    EXHIBIT A

                          REGISTRATION RIGHTS AGREEMENT

          This Registration Rights Agreement (this "Agreement") is made and
entered into as of June 22, 2006, by and between Rockwell Medical Technologies,
Inc., a Michigan corporation (the "Company") and Emerald Asset Advisors, LLC, a
limited liability company organized under the laws of the state of Delaware (the
"Purchaser").

          This Agreement is made pursuant to the Securities Purchase Agreement,
dated as of the date hereof between the Company and the Purchaser (the "Purchase
Agreement").

          The Company and the Purchaser hereby agree as follows:

     1. Definitions. Capitalized terms used and not otherwise defined herein
that are defined in the Purchase Agreement shall have the meanings given such
terms in the Purchase Agreement. As used in this Agreement, the following terms
shall have the following meanings:

          "Advice" shall have the meaning set forth in Section 6(d).

          "Effectiveness Period" shall have the meaning set forth in Section
     2(a).

          "Event" shall have the meaning set forth in Section 2(b).

          "Event Date" shall have the meaning set forth in Section 2(b).

          "Filing Date" means, with respect to the Registration Statement
     required to be filed hereunder, on or before the 60th day following the
     Closing Date.

          "Holder" or "Holders" means the holder or holders, as the case may be,
     from time to time of Registrable Securities.

          "Indemnified Party" shall have the meaning set forth in Section 5(c).

          "Indemnifying Party" shall have the meaning set forth in Section 5(c).

          "Losses" shall have the meaning set forth in Section 5(a).

          "Plan of Distribution" shall have the meaning set forth in Section
     2(a).

          "Proceeding" means an action, claim, suit, investigation or proceeding
     (including, without limitation, an investigation or partial proceeding,
     such as a deposition), whether commenced or threatened.

          "Prospectus" means the prospectus included in the Registration
     Statement (including, without limitation, a prospectus that includes any
     information previously omitted from a prospectus filed as part of an
     effective registration statement in reliance upon Rule 430A promulgated
     under the Securities Act), as amended or supplemented by any prospectus
     supplement, with respect to the terms of the offering of any portion of the
     Registrable Securities covered by the Registration Statement, and all other
     amendments


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     and supplements to the Prospectus, including post-effective amendments, and
     all material incorporated by reference or deemed to be incorporated by
     reference in such Prospectus.

          "Registrable Securities" means all of the Shares, together with any
     shares of Common Stock issued or issuable upon any stock split, dividend or
     other distribution, recapitalization or similar event with respect to the
     Shares, but only a period of 12 months following the Closing Date.

          "Registration Statement" means the registration statements required to
     be filed hereunder, including (in each case) the Prospectus, amendments and
     supplements to the registration statement or Prospectus, including pre- and
     post-effective amendments, all exhibits thereto, and all material
     incorporated by reference or deemed to be incorporated by reference in the
     registration statement.

          "Rule 415" means Rule 415 promulgated by the Commission pursuant to
     the Securities Act, as such Rule may be amended from time to time, or any
     similar rule or regulation hereafter adopted by the Commission having
     substantially the same purpose and effect as such Rule.

          "Rule 424" means Rule 424 promulgated by the Commission pursuant to
     the Securities Act, as such Rule may be amended from time to time, or any
     similar rule or regulation hereafter adopted by the Commission having
     substantially the same purpose and effect as such Rule.

          "Selling Shareholder Questionnaire" shall have the meaning set forth
     in Section 3(a).

     2. Registration.

          (a) On or prior to the Filing Date, the Company shall prepare and file
with the Commission the Registration Statement covering the offer and sale of
all of the Registrable Securities with the offer to be made on a continuous
basis pursuant to Rule 415. The Registration Statement required hereunder shall
be on Form S-3 (except if the Company is not then eligible to register for
resale the Registrable Securities on Form S-3 or the SEC otherwise takes the
position that Form S-3 is not the appropriate form for the offer and sale of the
Registrable Securities), in which case the Registration shall be on another
appropriate form in accordance herewith). The Registration Statement required
hereunder shall contain (except if otherwise directed by the Holder and agreed
to by the Company) a description of the Plan of Distribution which will include,
but not necessarily be limited to, the information and substance included in
Annex A attached hereto (the "Plan of Distribution"). Subject to the terms of
this Agreement, the Company shall use its reasonable efforts to cause the
Registration Statement to be declared effective under the Securities Act as
promptly as practical after the filing thereof, and shall use its reasonable
efforts to keep the Registration Statement continuously effective under the
Securities Act until the date when all Registrable Securities covered by the
Registration Statement have been sold or until the date which is the first
anniversary of the date of this Agreement (the "Effectiveness Period"). The
Company shall notify the Holders via facsimile of


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the effectiveness of the Registration Statement no later than the following
Trading Day that the Company receives notification of the effectiveness from the
Commission.

          (b) If: (i) a Registration Statement is not filed on or prior to the
Filing Date (if the Company files a Registration Statement without affording
Holder the opportunity to review and comment on the same as required by Section
3(a), the Company shall not be deemed to have satisfied this clause (i)), or
(ii) the Registration Statement has not been declared effective by the
Commission within ninety (90) days of the Closing Date (or within one hundred
twenty (120) days if the Registration Statement receives a "full review" from
the Commission or (iii) the Company fails to file with the Commission a request
for acceleration in accordance with Rule 461 promulgated under the Securities
Act, within five Trading Days after the date that the Company is notified
(orally or in writing, whichever is earlier) by the Commission that a
Registration Statement will not be "reviewed," or is not subject to further
review, or (iv) prior to the date when such Registration Statement is first
declared effective by the Commission, the Company fails to file a pre-effective
amendment and otherwise respond in writing to comments made by the Commission in
respect of such Registration Statement within 20 calendar days after the receipt
of comments by or notice from the Commission that such amendment is required in
order for a Registration Statement to be declared effective, or (iv) after a
Registration Statement is first declared effective by the Commission, it ceases
for any reason to remain continuously effective as to all Registrable Securities
for which it is required to be effective, or the Holders are not permitted to
utilize the Prospectus therein to resell such Registrable Securities, for in any
such case 20 consecutive calendar days but no more than an aggregate of 60
calendar days during any 12 month period (which need not be consecutive Trading
Days)(any such failure or breach being referred to as an "Event," and for
purposes of clause (i), (ii) or (iv) the date on which such Event occurs, or for
purposes of clause (iii) the date on which such three Trading Day period is
exceeded, or for purposes of clause (iv) the date which such 20 calendar day
period is exceeded, or for purposes of clause (iv) the date on which such 20 or
60 calendar day period, as applicable, is exceeded being referred to as "Event
Date"), then in addition to any other rights the Holders may have hereunder or
under applicable law, then, on each such Event Date and on each monthly
anniversary of each such Event Date (if the applicable Event shall not have been
cured by such date) until the applicable Event is cured, the Company shall pay
to each Holder an amount in cash, as partial liquidated damages and not as a
penalty, equal to 1.0% per month of the aggregate purchase price paid by Holder
pursuant to the Purchase Agreement for any Registrable Securities then held by
Holder (such amount to be prorated for partial months), up to a maximum of 9.0%.
If the Company fails to pay any partial liquidated damages pursuant to this
Section in full within seven days after the date payable, the Company will pay
interest thereon at a rate of 18% per annum (or such lesser maximum amount that
is permitted to be paid by applicable law) to the Holder, accruing daily from
the date such partial liquidated damages are due until such amounts, plus all
such interest thereon, are paid in full.

     3. Registration Procedures

          In connection with the Company's registration obligations hereunder,
the Company shall:

          (a) Not less than five Trading Days prior to the filing of the
     Registration Statement or any related Prospectus or any amendment or
     supplement thereto (i) furnish


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     to Holder copies of all such documents proposed to be filed (including
     documents incorporated or deemed incorporated by reference to the extent
     requested by such Person) which documents will be subject to the review of
     Holder, and (ii) cause its officers and directors, counsel and independent
     certified public accountants to consider such inquiries and comments as may
     be made by Holder and its advisors. Holder agrees to furnish to the Company
     a completed Questionnaire in the form attached to this Agreement as Annex B
     (a "Selling Shareholder Questionnaire") not less than two Trading Days
     prior to the Filing Date or by the end of the fourth Trading Day following
     the date on which Holder receives draft materials in accordance with this
     Section. The Filing Date and 90-day and 120-day periods specified in
     Section 2(b)(ii) above shall extended for such period of time as is
     reasonably required to respond to and resolve inquiries or objections from
     the Holder.

          (b) (i) Prepare and file with the Commission such amendments,
     including post-effective amendments, to the Registration Statement and the
     Prospectus used in connection therewith as may be necessary to keep the
     Registration Statement continuously effective as to the applicable
     Registrable Securities for the Effectiveness Period and prepare and file
     with the Commission such additional Registration Statements in order to
     register for resale under the Securities Act all of the Registrable
     Securities; (ii) cause the related Prospectus to be amended or supplemented
     by any required Prospectus supplement, and as so supplemented or amended to
     be filed pursuant to Rule 424; (iii) respond as promptly as reasonably
     possible to any comments received from the Commission with respect to the
     Registration Statement or any amendment thereto and, as promptly as
     reasonably possible, upon request, provide the Holder true and complete
     copies of all correspondence from and to the Commission relating to the
     Registration Statement; and (iv) comply in all material respects with the
     provisions of the Securities Act and the Exchange Act with respect to the
     disposition of all Registrable Securities covered by the Registration
     Statement during the applicable period in accordance with the intended
     methods of disposition by the Holder set forth in the Registration
     Statement as so amended or in such Prospectus as so supplemented.

          (c) Notify the Holder of Registrable Securities to be sold, as
     promptly as reasonably practical and confirm such notice in writing
     promptly following the day (i)(A) when a Prospectus or any Prospectus
     supplement or post-effective amendment to the Registration Statement is
     proposed to be filed; (B) when the Commission notifies the Company whether
     there will be a "review" of the Registration Statement and whenever the
     Commission comments in writing on the Registration Statement (the Company
     shall upon request provide true and complete copies thereof and all written
     responses thereto to Holder); and (C) with respect to the Registration
     Statement or any post-effective amendment, when the same has become
     effective; (ii) of any request by the Commission or any other Federal or
     state governmental authority during the period of effectiveness of the
     Registration Statement for amendments or supplements to the Registration
     Statement or Prospectus or for additional information; (iii) of the
     issuance by the Commission or any other federal or state governmental
     authority of any stop order suspending the effectiveness of the
     Registration Statement covering any or all of the Registrable Securities or
     the initiation of any Proceedings for that purpose; (iv) of the receipt by
     the Company of any notification with respect to the suspension of the
     qualification or


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     exemption from qualification of any of the Registrable Securities for sale
     in any jurisdiction, or the initiation or threatening of any Proceeding for
     such purpose; and (v) of the occurrence of any event or passage of time
     that makes the financial statements included in the Registration Statement
     ineligible for inclusion therein or any statement made in the Registration
     Statement or Prospectus or any document incorporated or deemed to be
     incorporated therein by reference untrue in any material respect or that
     requires any revisions to the Registration Statement, Prospectus or other
     documents so that, in the case of the Registration Statement or the
     Prospectus, as the case may be, it will not contain any untrue statement of
     a material fact or omit to state any material fact required to be stated
     therein or necessary to make the statements therein, in light of the
     circumstances under which they were made, not misleading.

          (d) Use reasonable efforts to avoid the issuance of, or, if issued,
     obtain the withdrawal of (i) any order suspending the effectiveness of the
     Registration Statement, or (ii) any suspension of the qualification (or
     exemption from qualification) of any of the Registrable Securities for sale
     in any jurisdiction, at the earliest practicable moment.

          (e) Furnish to Holder, without charge, at least one conformed copy of
     the Registration Statement and each amendment thereto, including financial
     statements and schedules, all documents incorporated or deemed to be
     incorporated therein by reference to the extent requested by such Person,
     and all exhibits to the extent requested by such Person (including those
     previously furnished or incorporated by reference) promptly after the
     filing of such documents with the Commission.

          (f) Promptly deliver to Holder, without charge, as many copies of the
     Prospectus or Prospectuses and each amendment or supplement thereto as such
     Persons may reasonably request in connection with resales by the Holder of
     Registrable Securities. Subject to the terms of this Agreement, the Company
     hereby consents to the use of such Prospectus and each amendment or
     supplement thereto by the selling Holders in connection with the offering
     and sale of the Registrable Securities covered by such Prospectus and any
     amendment or supplement thereto, except after the giving on any notice
     pursuant to Section 3(c).

          (g) Prior to any resale of Registrable Securities by Holder, use its
     commercially reasonable efforts to register or qualify or cooperate with
     the selling Holder in connection with the registration or qualification (or
     exemption from the Registration or qualification) of such Registrable
     Securities for the resale by the Holder under the securities or Blue Sky
     laws of such jurisdictions within the United States as any Holder
     reasonably requests in writing (but not more than two such jurisdictions),
     to keep the Registration or qualification (or exemption therefrom)
     effective during the Effectiveness Period and to do any and all other acts
     or things reasonably necessary to enable the disposition in such
     jurisdictions of the Registrable Securities covered by the Registration
     Statement; provided, that the Company shall not be required to qualify
     generally to do business in any jurisdiction where it is not then so
     qualified, subject the Company to any material tax in any such jurisdiction
     where it is not then so subject or file a general consent to service of
     process in any such jurisdiction.


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          (h) If NASDR Rule 2710 requires any broker-dealer to make a filing
     prior to executing a sale by a Holder, make an Issuer Filing with the
     NASDR, Inc. Corporate Financing Department pursuant to NASDR Rule
     2710(b)(10)(A)(i) and use reasonable efforts to respond within five Trading
     Days to any comments received from NASDR in connection therewith.

          (i) If requested by the Holder, cooperate with the Holder to
     facilitate the timely preparation and delivery of certificates representing
     Registrable Securities to be delivered to a transferee pursuant to the
     Registration Statement, which certificates shall be free, to the extent
     permitted by the Purchase Agreement, of all restrictive legends, and to
     enable such Registrable Securities to be in such denominations and
     registered in such names as Holder may request.

          (j) Upon the occurrence of any event contemplated by Section 3(c)(v),
     as promptly as reasonably, possible, prepare a supplement or amendment,
     including a post-effective amendment, to the Registration Statement or a
     supplement to the related Prospectus or any document incorporated or deemed
     to be incorporated therein by reference, and file any other required
     document so that, as thereafter delivered, neither the Registration
     Statement nor such Prospectus will contain an untrue statement of a
     material fact or omit to state a material fact required to be stated
     therein or necessary to make the statements therein, in light of the
     circumstances under which they were made, not misleading. If the Company
     notifies the Holder in accordance with clauses (ii) through (v) of Section
     3(c) above to suspend the use of any Prospectus until the requisite changes
     to such Prospectus have been made, then the Holder shall suspend use of
     such Prospectus. The Company will use its reasonable efforts to ensure that
     the use of the Prospectus may be resumed as promptly as is practicable. The
     Company shall be entitled to exercise its right under this Section 3(j) to
     suspend the availability of a Registration Statement and Prospectus, for a
     period not to exceed 90 days (which need not be consecutive days) in any 12
     month period.

          (k) Comply with all applicable rules and regulations of the
     Commission.

          (l) The Company may require Holder to furnish to the Company a
     certified statement as to the number of shares of Common Stock beneficially
     owned by Holder and, if required by the Commission, the person thereof that
     has voting and dispositive control over the Shares. During any periods that
     the Company is unable to meet its obligations hereunder with respect to the
     registration of the Registrable Securities solely because any Holder fails
     to furnish such information within three Trading Days of the Company's
     request, any liquidated damages that are accruing at such time as to Holder
     shall be tolled and any Event that may otherwise occur solely because of
     such delay shall be suspended as to Holder until such information is
     delivered to the Company.

     4. Registration Expenses. All fees and expenses incident to the performance
of or compliance with this Agreement by the Company shall be borne by the
Company whether or not any Registrable Securities are sold pursuant to the
Registration Statement. The fees and expenses referred to in the foregoing
sentence shall include, without limitation, (i) all registration and filing fees
(including, without limitation, fees and expenses (A) with respect to filings


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required to be made with the Trading Market on which the Common Stock is then
listed for trading, (B) in compliance with applicable state securities or Blue
Sky laws reasonably agreed to by the Company in writing (including, without
limitation, fees and disbursements of counsel for the Company in connection with
Blue Sky qualifications or exemptions (in not more than two jurisdictions) of
the Registrable Securities and determination of the eligibility of the
Registrable Securities for investment under the laws of such two jurisdictions
as requested by the Holders), (ii) printing expenses (including, without
limitation, expenses of printing certificates for Registrable Securities and of
printing prospectuses if the printing of prospectuses is reasonably requested by
the holders of a majority of the Registrable Securities included in the
Registration Statement), (iii) messenger, telephone and delivery expenses, (iv)
fees and disbursements of counsel for the Company, (v) Securities Act liability
insurance, if the Company so desires such insurance, and (vi) fees and expenses
of all other Persons retained by the Company in connection with the consummation
of the transactions contemplated by this Agreement. In addition, the Company
shall be responsible for all of its internal expenses incurred in connection
with the consummation of the transactions contemplated by this Agreement
(including, without limitation, all salaries and expenses of its officers and
employees performing legal or accounting duties), the expense of any annual
audit and the fees and expenses incurred in connection with the listing of the
Registrable Securities on any securities exchange as required hereunder. In no
event shall the Company be responsible for any broker or similar commissions,
broker costs or expense (including without limitation, any costs or expenses
associated with any necessary Filing with the NASDR, Inc. Corporate Financing
Department pursuant to NASDR Rule 2710(b)(10)(A)(i)), the costs or expenses
associated with any Blue Sky qualifications or exemptions (or the determination
of their application) in more than two jurisdictions, or, except to the extent
specifically provided for in this Agreement, any legal fees or other costs of
the Purchaser.

     5. Indemnification

          (a) Indemnification by the Company. The Company shall, notwithstanding
     any termination of this Agreement, indemnify and hold harmless Holder and
     each of its officers, directors, agents and employees, each Person who
     controls any Holder (within the meaning of Section 15 of the Securities Act
     or Section 20 of the Exchange Act) and the officers, directors, agents and
     employees of each such controlling Person, to the fullest extent permitted
     by applicable law, from and against any and all losses, claims, damages,
     liabilities, costs (including, without limitation, reasonable attorneys'
     fees) and expenses (collectively, "Losses"), as incurred, arising out of or
     relating to any untrue or alleged untrue statement of a material fact
     contained in the Registration Statement, any Prospectus or in any amendment
     or supplement thereto or in any preliminary prospectus, or arising out of
     or relating to any omission or alleged omission of a material fact required
     to be stated therein or necessary to make the statements therein (in the
     case of any Prospectus or supplement thereto, in light of the circumstances
     under which they were made) not misleading, except to the extent, but only
     to the extent, that (i) such untrue statements or omissions are based
     solely upon information regarding Holder furnished in writing to the
     Company by Holder expressly for use therein, or to the extent that such
     information relates to Holder or Holder's proposed method of distribution
     of Registrable Securities and was reviewed and expressly approved in
     writing by Holder expressly for use in the Registration Statement, such
     Prospectus or in any amendment or


                                       7



     supplement thereto (it being understood that the Holder has approved Annex
     A hereto for this purpose) or (ii) in the case of an occurrence of an event
     of the type specified in Section 3(c)(ii)-(v), the use by Holder of an
     outdated or defective Prospectus after the Company has notified Holder in
     writing that the Prospectus is outdated or defective and prior to the
     receipt by Holder of the Advice contemplated in Section 6(d). The Company
     shall notify the Holder promptly of the institution, threat or assertion of
     any Proceeding of which the Company is aware in connection with the
     transactions contemplated by this Agreement.

          (b) Indemnification by Holder. Holder shall indemnify and hold
     harmless the Company, its directors, officers, agents and employees, each
     Person who controls the Company (within the meaning of Section 15 of the
     Securities Act and Section 20 of the Exchange Act), and the directors,
     officers, agents or employees of such controlling Persons, to the fullest
     extent permitted by applicable law, from and against all Losses, as
     incurred, to the extent arising out of or based solely upon: (x) Holder's
     failure to comply with the prospectus delivery requirements of the
     Securities Act or (y) any untrue or alleged untrue statement of a material
     fact contained in any Registration Statement, any Prospectus or in any
     amendment or supplement thereto or in any preliminary prospectus, or
     arising out of or relating to any omission or alleged omission of a
     material fact required to be stated therein or necessary to make the
     statements therein not misleading (i) to the extent, but only to the
     extent, that such untrue statement or omission is contained in any
     information so furnished in writing by Holder to the Company specifically
     for inclusion in the Registration Statement or such Prospectus or (ii) to
     the extent that (1) such untrue statements or omissions are based solely
     upon information regarding Holder furnished in writing to the Company by
     Holder expressly for use therein, or to the extent that such information
     relates to Holder or Holder's proposed method of distribution of
     Registrable Securities and was reviewed and expressly approved in writing
     by Holder expressly for use in the Registration Statement (it being
     understood that the Holder has approved Annex A hereto for this purpose),
     such Prospectus or in any amendment or supplement thereto or (2) in the
     case of an occurrence of an event of the type specified in Section
     3(c)(ii)-(v), the use by Holder of an outdated or defective Prospectus
     after the Company has notified Holder in writing that the Prospectus is
     outdated or defective and prior to the receipt by Holder of the Advice
     contemplated in Section 6(d). In no event shall the liability of Holder
     hereunder be greater in amount than the dollar amount of the net proceeds
     received by Holder upon the sale of the Registrable Securities giving rise
     to such indemnification obligation.

          (c) Conduct of Indemnification Proceedings. If any Proceeding shall be
     brought or asserted against any Person entitled to indemnity hereunder (an
     "Indemnified Party"), such Indemnified Party shall promptly notify the
     Person from whom indemnity is sought (the "Indemnifying Party") in writing,
     and the Indemnifying Party shall have the right to assume the defense
     thereof, including the employment of counsel reasonably satisfactory to the
     Indemnified Party and the payment of all fees and expenses incurred in
     connection with defense thereof; provided, that the failure of any
     Indemnified Party to give such notice shall not relieve the Indemnifying
     Party of its obligations or liabilities pursuant to this Agreement, except
     (and only) to the extent that it shall be finally


                                       8



     determined by a court of competent jurisdiction (which determination is not
     subject to appeal or further review) that such failure shall have
     prejudiced the Indemnifying Party.

          An Indemnified Party shall have the right to employ separate counsel
     in any such Proceeding and to participate in the defense thereof, but the
     fees and expenses of such counsel shall be at the expense of such
     Indemnified Party or Parties unless: (1) the Indemnifying Party has agreed
     in writing to pay such fees and expenses; (2) the Indemnifying Party shall
     have failed promptly to assume the defense of such Proceeding and to employ
     counsel reasonably satisfactory to such Indemnified Party in any such
     Proceeding; or (3) the named parties to any such Proceeding (including any
     impleaded parties) include both such Indemnified Party and the Indemnifying
     Party, and such Indemnified Party shall reasonably believe that a material
     conflict of interest is likely to exist if the same counsel were to
     represent such Indemnified Party and the Indemnifying Party (in which case,
     if such Indemnified Party notifies the Indemnifying Party in writing that
     it elects to employ separate counsel at the expense of the Indemnifying
     Party, the Indemnifying Party shall not have the right to assume the
     defense thereof and the reasonable fees and expenses of one separate
     counsel shall be at the expense of the Indemnifying Party). For purposes of
     this Section 5(c), the term "conflict of interest" shall mean that there
     are one or more legal defenses available to the Indemnified Party that are
     different from or additional to those available to the Indemnifying Party
     or such other Indemnified Parties, as applicable, which different or
     additional defenses make joint representation inappropriate. The
     Indemnifying Party shall not be liable for any settlement of any such
     Proceeding effected without its prior written consent, which consent shall
     not be unreasonably withheld. No Indemnifying Party shall, without the
     prior written consent of the Indemnified Party, effect any settlement of
     any pending Proceeding in respect of which any Indemnified Party is a
     party, unless such settlement includes an unconditional release of such
     Indemnified Party from all liability on claims that are the subject matter
     of such Proceeding.

          Subject to the terms of this Agreement, all reasonable fees and
     expenses of the Indemnified Party (including reasonable fees and expenses
     to the extent incurred in connection with investigating or preparing to
     defend such Proceeding in a manner not inconsistent with this Section)
     shall be paid to the Indemnified Party, as incurred, within ten Trading
     Days of written notice thereof to the Indemnifying Party; provided, that
     the Indemnified Party shall promptly reimburse the Indemnifying Party for
     that portion of such fees and expenses applicable to such actions for which
     such Indemnified Party is not entitled to indemnification hereunder,
     determined based upon the relative faults of the parties.

          (d) Contribution. If the indemnification under Section 5(a) or 5(b) is
     unavailable to an Indemnified Party or insufficient to hold an Indemnified
     Party harmless for any Losses, then each Indemnifying Party shall
     contribute to the amount paid or payable by such Indemnified Party, in such
     proportion as is appropriate to reflect the relative fault of the
     Indemnifying Party and Indemnified Party in connection with the actions,
     statements or omissions that resulted in such Losses as well as any other
     relevant equitable considerations. The relative fault of such Indemnifying
     Party and Indemnified Party shall be determined by reference to, among
     other things, whether any action in


                                       9



     question, including any untrue or alleged untrue statement of a material
     fact or omission or alleged omission of a material fact, has been taken or
     made by, or relates to information supplied by, such Indemnifying Party or
     Indemnified Party, and the parties' relative intent, knowledge, access to
     information and opportunity to correct or prevent such action, statement or
     omission. The amount paid or payable by a party as a result of any Losses
     shall be deemed to include, subject to the limitations set forth in this
     Agreement, any reasonable attorneys' or other reasonable fees or expenses
     incurred by such party in connection with any Proceeding to the extent such
     party would have been indemnified for such fees or expenses if the
     indemnification provided for in this Section was available to such party in
     accordance with its terms.

          The parties hereto agree that it would not be just and equitable if
     contribution pursuant to this Section 5(d) were determined by pro rata
     allocation or by any other method of allocation that does not take into
     account the equitable considerations referred to in the immediately
     preceding paragraph. Notwithstanding the provisions of this Section 5(d),
     Holder shall not be required to contribute, in the aggregate, any amount in
     excess of the amount by which the proceeds actually received by Holder from
     the sale of the Registrable Securities subject to the Proceeding exceeds
     the amount of any damages that Holder has otherwise been required to pay by
     reason of such untrue or alleged untrue statement or omission or alleged
     omission, except in the case of fraud by Holder.

          The indemnity and contribution agreements contained in this Section
     are in addition to any liability that the Indemnifying Parties may have to
     the Indemnified Parties.

     6. Miscellaneous

          (a) Remedies. In the event of a breach by the Company or by Holder, of
     any of their obligations under this Agreement, Holder or the Company, as
     the case may be, in addition to being entitled to exercise all rights
     granted by law and under this Agreement, including recovery of damages,
     will be entitled to specific performance of its rights under this
     Agreement. The Company and Holder agree that monetary damages would not
     provide adequate compensation for any losses incurred by reason of a breach
     by it of any of the provisions of this Agreement and hereby further agrees
     that, in the event of any action for specific performance in respect of
     such breach, it shall waive the defense that a remedy at law would be
     adequate.

          (b) No Piggyback on Registrations. Except as set forth on Schedule
     6(b) attached hereto, neither the Company nor any of its security holders
     (other than the Holder in such capacity pursuant hereto) may include
     securities of the Company in a Registration Statement other than the
     Registrable Securities. No Person has any right to cause the Company to
     effect the registration under the Securities Act of any securities of the
     Company. The Company shall not file any other registration statements until
     the later to occur of: (i) 30 Trading Days following the date that the
     Registration Statement required hereunder is declared effective by the
     Commission, or (ii) 90 days following the Closing Date, provided that this
     Section 6(b) shall not prohibit the Company from filing amendments to
     registration statements already filed or filing a registration statement at


                                       10



     any time after the Registration Statement has been continuously effective
     for 60 days or the Purchaser has disposed of all Registrable Securities
     held by it.

          (c) Compliance. Holder covenants and agrees that it will comply with
     the prospectus delivery requirements of the Securities Act as applicable to
     it in connection with sales of Registrable Securities pursuant to the
     Registration Statement.

          (d) Discontinued Disposition. Holder agrees by its acquisition of such
     Registrable Securities that, upon receipt of a notice from the Company of
     the occurrence of any event of the kind described in Section 3(c), Holder
     will forthwith discontinue disposition of such Registrable Securities under
     the Registration Statement until Holder's receipt of the copies of the
     supplemented Prospectus and/or amended Registration Statement or until it
     is advised in writing (the "Advice") by the Company that the use of the
     applicable Prospectus may be resumed, and, in either case, has received
     copies of any additional or supplemental filings that are incorporated or
     deemed to be incorporated by reference in such Prospectus or Registration
     Statement. The Company will use its reasonable efforts to ensure that the
     use of the Prospectus may be resumed as promptly as is practicable. Except
     as otherwise provided in Section 3(j), the Company agrees and acknowledges
     that any periods during which the Holder is required to discontinue the
     disposition of the Registrable Securities hereunder shall be subject to the
     provisions of Section 2(b).

          (e) Piggy-Back Registrations. If at any time during the Effectiveness
     Period there is not an effective Registration Statement covering all of the
     Registrable Securities and the Company shall determine to prepare and file
     with the Commission a registration statement relating to an offering for
     its own account under the Securities Act of any of its equity securities,
     other than on Form S-4 or Form S-8 (each as promulgated under the
     Securities Act) or their then equivalents relating to equity securities to
     be issued solely in connection with any acquisition of any entity or
     business or equity securities issuable in connection with the stock option
     or other employee benefit plans, then the Company shall send to Purchaser a
     written notice of such determination and, if within fifteen days after the
     date of such notice, Holders shall so request in writing, the Company shall
     include in such registration statement all or any part of such Registrable
     Securities Holders request to be registered; provided, however, that (i) if
     such registration involves an underwritten offering to the public, all
     Holders electing to participate in such offering must sell their
     Registrable Securities to the underwriters selected by the Company on the
     same terms and conditions as apply to the Company; and (ii) if, at any time
     after giving notice of the Company's intention to register any securities
     pursuant to this 6(e) and prior to the effective date of the registration
     statement filed in connection with such registration, the Company shall
     determine for any reason not to register such securities, the Company shall
     give written notice to all Holders who have elected to participate in such
     offering and, thereupon, shall be relieved of its obligation to register
     any Registrable Securities in connection with such registration. If the
     managing underwriter of the underwritten offering shall inform the Company
     by letter of the underwriter's opinion that the number of Registrable
     Securities requested to be included in such registration would, in its
     opinion, materially adversely affect such offering, including the price at
     which such securities can be sold, and the Company has so advised the
     Holders electing to participate


                                       11


     in such offering in writing, then the Company shall include in such
     registration, to the extent of the number that the Company is so advised
     can be sold in (or during the time of) such offering, (i) first, all
     securities proposed by the Company to be sold for its own account, then
     (ii) to the extent that the number of shares of Common Stock proposed to be
     sold by the Company pursuant to this Section 6(e) is less than the number
     of shares of Common Stock that the Company has been advised can be sold in
     such offering without having the material adverse effect referred to above,
     such Registrable Securities requested to be included in such registration
     pursuant to this Section 6(d); allocated among the electing Holders pro
     rata in accordance with the number shares each such Holder requested by
     included in such offering.

          (f) Amendments and Waivers. The provisions of this Agreement,
     including the provisions of this sentence, may not be amended, modified or
     supplemented, and waivers or consents to departures from the provisions
     hereof may not be given, unless the same shall be in writing and signed by
     the Company and Purchaser.

          (g) Notices. Any and all notices or other communications or deliveries
     required or permitted to be provided hereunder shall be delivered as set
     forth in the Purchase Agreement.

          (h) Successors and Assigns. This Agreement shall inure to the benefit
     of and be binding upon the successors and permitted assigns of each of the
     parties and shall inure to the benefit of each Holder. The Company may not
     assign its rights or obligations hereunder without the prior written
     consent of Purchaser. Purchaser may assign its rights hereunder in the
     manner and to the Persons as permitted under the Purchase Agreement.

          (i) No Inconsistent Agreements. Neither the Company nor any of its
     subsidiaries has entered, as of the date hereof, nor shall the Company or
     any of its subsidiaries, on or after the date of this Agreement, enter into
     any agreement with respect to its securities, that would conflict with or
     violate the provisions hereof or of any of the Transaction Documents.
     Except as set forth on Schedule 6(i), neither the Company nor any of its
     subsidiaries has previously entered into any agreement granting any
     registration rights with respect to any of its securities to any Person
     that has not been satisfied in full.

          (j) Execution and Counterparts. This Agreement may be executed in any
     number of counterparts, each of which when so executed shall be deemed to
     be an original and, all of which taken together shall constitute one and
     the same Agreement. In the event that any signature is delivered by
     facsimile transmission, such signature shall create a valid binding
     obligation of the party executing (or on whose behalf such signature is
     executed) the same with the same force and effect as if such facsimile
     signature were the original thereof.

          (k) Governing Law. All questions concerning the construction,
     validity, enforcement and interpretation of this Agreement shall be
     determined with the provisions of the Purchase Agreement.


                                       12



          (l) Cumulative Remedies. The remedies provided herein are cumulative
     and not exclusive of any remedies provided by law.

          (m) Severability. If any term, provision, covenant or restriction of
     this Agreement is held by a court of competent jurisdiction to be invalid,
     illegal, void or unenforceable, the remainder of the terms, provisions,
     covenants and restrictions set forth herein shall remain in full force and
     effect and shall in no way be affected, impaired or invalidated, and the
     parties hereto shall use their commercially reasonable efforts to find and
     employ an alternative means to achieve the same or substantially the same
     result as that contemplated by such term, provision, covenant or
     restriction. It is hereby stipulated and declared to be the intention of
     the parties that they would have executed the remaining terms, provisions,
     covenants and restrictions without including any of such that may be
     hereafter declared invalid, illegal, void or unenforceable.

          (n) Headings. The headings in this Agreement are for convenience of
     reference only and shall not limit or otherwise affect the meaning hereof.

                            *************************


                                       13



          IN WITNESS WHEREOF, the parties have executed this Registration Rights
Agreement as of the date first written above.

                                        ROCKWELL MEDICAL TECHNOLOGIES, INC.


                                        By: /S/ Robert Chioini
                                            ------------------------------------
                                        Name: Robert Chioini
                                        Title: President and Chief Executive
                                               Officer


                                        EMERALD ASSET ADVISORS, LLC


                                        By: /S/ Michael Xirinachs
                                            ------------------------------------
                                        Name: Michael Xirinachs
                                        Title: Managing Member


                                     ANNEX A

                              Plan of Distribution

     The Selling Stockholders (the "Selling Stockholders") of the common stock
("Common Stock") of Rockwell Medical Technologies, Inc., a Michigan corporation
(the "Company") and any of their pledgees, assignees and successors-in-interest
may, from time to time, sell any or all of their shares of Common Stock on any
stock exchange, market or trading facility on which the shares are traded or in
private transactions. These sales may be at fixed, negotiated or market prices.
The Selling Stockholders may use any one or more of the following methods when
selling shares:

     -    ordinary brokerage transactions and transactions in which the
          broker-dealer solicits purchasers;

     -    block trades in which the broker-dealer will attempt to sell the
          shares as agent but may position and resell a portion of the block as
          principal to facilitate the transaction;

     -    purchases by a broker-dealer as principal and resale by the
          broker-dealer for its account;

     -    an exchange distribution in accordance with the rules of the
          applicable exchange;

     -    privately negotiated transactions;

     -    settlement of short sales entered into after the date of this
          prospectus;

     -    broker-dealers may agree with the Selling Stockholders to sell a
          specified number of such shares at a stipulated price per share;

     -    a combination of any such methods of sale;

     -    through the writing or settlement of options or other hedging
          transactions, whether through an options exchange or otherwise; or

     -    any other method permitted pursuant to applicable law.

     The Selling Stockholders may also sell shares under Rule 144 under the
Securities Act of 1933, as amended (the "Securities Act"), if available, rather
than under this prospectus.

     Broker-dealers engaged by the Selling Stockholders may arrange for other
brokers-dealers to participate in sales. Broker-dealers may receive commissions
or discounts from the Selling Stockholders (or, if any broker-dealer acts as
agent for the purchaser of shares, from the purchaser) in amounts to be
negotiated, but, except as set forth in a supplement to this Prospectus, in the
case of an agency transaction not in excess of a customary brokerage commission
in compliance with NADSR Rule 2440; and in the case of a principal transaction a
markup or markdown in compliance with NASDR IM-2440.


                                       15



     In connection with the sale of the Common Stock or interests therein, the
Selling Stockholders may enter into hedging transactions with broker-dealers or
other financial institutions, which may in turn engage in short sales of the
Common Stock in the course of hedging the positions they assume. The Selling
Stockholders may also, on or after the date of this Prospectus, sell shares of
the Common Stock short and deliver these securities to close out their short
positions, or loan or pledge the Common Stock to broker-dealers that in turn may
sell these securities. The Selling Stockholders may also enter into option or
other transactions with broker-dealers or other financial institutions or the
creation of one or more derivative securities which require the delivery to such
broker-dealer or other financial institution of shares offered by this
prospectus, which shares such broker-dealer or other financial institution may
resell pursuant to this prospectus (as supplemented or amended to reflect such
transaction).

     The Selling Stockholders and any broker-dealers or agents that are involved
in selling the shares may be deemed to be "underwriters" within the meaning of
the Securities Act in connection with such sales. In such event, any commissions
received by such broker-dealers or agents and any profit on the resale of the
shares purchased by them may be deemed to be underwriting commissions or
discounts under the Securities Act. Each Selling Stockholder has informed the
Company that it does not have any written or oral agreement or understanding,
directly or indirectly, with any person to distribute the Common Stock. In no
event shall any broker-dealer receive fees, commissions and markups which, in
the aggregate, would exceed eight percent (8%) of the market price of the Common
Stock.

     In the event the Selling Stockholders are deemed to be "underwriters"
within the meaning of the Securities Act with respect to the Common Stock, any
difference between the price at which they purchased the Common Stock and the
market price of the Common Stock could be deemed to be a discount or commission
and such deemed discount or commission could exceed eight percent (8%) of the
market price of the Common Stock.

     The Company is required to pay the fees and expenses incurred by the
Company incident to the registration of the shares as well as certain of the
fees and expenses of the Selling Stockholders. The Company has agreed to
indemnify the Selling Stockholders against certain losses, claims, damages and
liabilities, including liabilities under the Securities Act. The Selling
Stockholders have agreed to indemnify the Company against certain losses,
claims, damages and liabilities, including liabilities under the Securities Act
arising out of or relating to any omission or alleged omission of a material
fact required to be stated herein or necessary to make the statements herein not
misleading (i) to the extent, but only to the extent, that such untrue statement
or omission is contained in any information so furnished in writing by Selling
Stockholder to the Company specifically for inclusion herein or (ii) to the
extent that (1) such untrue statements or omissions are based solely upon
information regarding Selling Stockholder furnished in writing to the Company by
Selling Stockholder expressly for use herein.

     Because Selling Stockholders may be deemed to be "underwriters" within the
meaning of the Securities Act, they will be subject to the prospectus delivery
requirements of the Securities Act. In addition, any securities covered by this
prospectus which qualify for sale pursuant to Rule 144 under the Securities Act
may be sold under Rule 144 rather than under this prospectus. Each Selling
Stockholder has advised us that they have not entered into any written or oral
agreements, understandings or arrangements with any underwriter or broker-dealer
regarding the


                                       16



sale of the resale shares. There is no underwriter or coordinating broker acting
in connection with the proposed sale of the resale shares by the Selling
Stockholders.

     We agreed to keep this prospectus effective for a period of 60 consecutive
days. The resale shares will be sold only through registered or licensed brokers
or dealers if required under applicable state securities laws. In addition, in
certain states, the resale shares may not be sold unless they have been
registered or qualified for sale in the applicable state or an exemption from
the registration or qualification requirement is available and is complied with.

     Under applicable rules and regulations under the Exchange Act, any person
engaged in the distribution of the resale shares may not simultaneously engage
in market making activities with respect to the Common Stock for a period of two
business days prior to the commencement of the distribution. In addition, the
Selling Stockholders will be subject to applicable provisions of the Exchange
Act and the rules and regulations thereunder, including Regulation M, which may
limit the timing of purchases and sales of shares of the Common Stock by the
Selling Stockholders or any other person. We will make copies of this prospectus
available to the Selling Stockholders and have informed them of the need to
deliver a copy of this prospectus to each purchaser at or prior to the time of
the sale.

     [NEED TO ADD DISCLOSURE OF ANY RELATIONSHIP BETWEEN PURCHASER AND COMPANY]

     [NEED TO ADD ESTIMATE OF FEES AND EXPENSES TO BE PAID BY THE COMPANY]


                                       17



                                                                         ANNEX B

                       ROCKWELL MEDICAL TECHNOLOGIES, INC.

                 SELLING SECURITYHOLDER NOTICE AND QUESTIONNAIRE

     The undersigned beneficial owner of common stock, no par value per share
(the "Common Stock") of Rockwell Medical Technologies, Inc., a Michigan
corporation (the "Company"), (the "Registrable Securities") understands that the
Company has filed or intends to file with the Securities and Exchange Commission
(the "Commission") a registration statement on Form S-3 (the "Registration
Statement") for the registration and resale under Rule 415 of the Securities Act
of 1933, as amended (the "Securities Act"), of the Registrable Securities, in
accordance with the terms of the Registration Rights Agreement, dated as of June
___, 2006 (the "Registration Rights Agreement"), among the Company and the
Purchaser named therein. A copy of the Registration Rights Agreement is
available from the Company upon request at the address set forth below. All
capitalized terms not otherwise defined herein shall have the meanings ascribed
thereto in the Registration Rights Agreement.

     Certain legal consequences arise from being named as a selling
securityholder in the Registration Statement and the related prospectus.
Accordingly, holders and beneficial owners of Registrable Securities are advised
to consult their own securities law counsel regarding the consequences of being
named or not being named as a selling securityholder in the Registration
Statement and the related prospectus.

                                     NOTICE

     The undersigned beneficial owner (the "Selling Securityholder") of
Registrable Securities hereby elects to include the Registrable Securities owned
by it and listed below in Item 3 (unless otherwise specified under such Item 3)
in the Registration Statement.


                                       18



The undersigned hereby provides the following information to the Company and
represents and warrants that such information is accurate:

                                  QUESTIONNAIRE

1.   NAME.

     (a)  Full Legal Name of Selling Securityholder

          ______________________________________________________________________

     (b)  Full Legal Name of Registered Holder (if not the same as (a) above)
          through which Registrable Securities Listed in Item 3 below are held:

          ______________________________________________________________________

     (c)  Full Legal Name of Natural Control Person (which means a natural
          person who directly you indirectly alone or with others has power to
          vote or dispose of the securities covered by the questionnaire):

          ______________________________________________________________________

2.   ADDRESS FOR NOTICES TO SELLING SECURITYHOLDER:

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________________

Telephone: _____________________________________________________________________

Fax: ___________________________________________________________________________

Contact Person: ________________________________________________________________

3.   BENEFICIAL OWNERSHIP OF REGISTRABLE SECURITIES:

     (a)  Type and Number of Registrable Securities beneficially owned:

          ______________________________________________________________________

          ______________________________________________________________________

          ______________________________________________________________________


                                       19



4.   BROKER-DEALER STATUS:

     (a)  Are you a broker-dealer?

          Yes [ ]   No [ ]

     Note: If yes, the Commission's staff has indicated that you should be
          identified as an underwriter in the Registration Statement.

     (b)  Are you an affiliate of a broker-dealer?

          Yes [ ]   No [ ]

     (c)  If you are an affiliate of a broker-dealer, do you certify that you
          bought the Registrable Securities in the ordinary course of business,
          and at the time of the purchase of the Registrable Securities to be
          resold, you had no agreements or understandings, directly or
          indirectly, with any person to distribute the Registrable Securities?

          Yes [ ]   No [ ]

     Note: If no, the Commission's staff has indicated that you should be
          identified as an underwriter in the Registration Statement.

5.   BENEFICIAL OWNERSHIP OF OTHER SECURITIES OF THE COMPANY OWNED BY THE
     SELLING SECURITYHOLDER.

     Except as set forth below in this Item 5, the undersigned is not the
     beneficial or registered owner of any securities of the Company other than
     the Registrable Securities listed above in Item 3.

     (a)  Type and Amount of Other Securities beneficially owned by the Selling
          Securityholder:

          ______________________________________________________________________

          ______________________________________________________________________


                                       20



6.   RELATIONSHIPS WITH THE COMPANY:

     Except as set forth below, neither the undersigned nor any of its
     affiliates, officers, directors or principal equity holders (owners of 5%
     of more of the equity securities of the undersigned) has held any position
     or office or has had any other material relationship with the Company (or
     its predecessors or affiliates) during the past three years.

     State any exceptions here:

     ___________________________________________________________________________

     ___________________________________________________________________________

     The undersigned agrees to promptly notify the Company of any inaccuracies
or changes in the information provided herein that may occur subsequent to the
date hereof at any time while the Registration Statement remains effective.

     By signing below, the undersigned consents to the disclosure of the
information contained herein in its answers to Items 1 through 6 and the
inclusion of such information in the Registration Statement and the related
prospectus. The undersigned understands that such information will be relied
upon by the Company in connection with the preparation or amendment of the
Registration Statement and the related prospectus.

     IN WITNESS WHEREOF the undersigned, by authority duly given, has caused
this Notice and Questionnaire to be executed and delivered either in person or
by its duly authorized agent.

Dated:                                  Beneficial Owner:
       -------------------                                ----------------------


                                        By:
                                            ------------------------------------
                                        Name:
                                              ----------------------------------
                                        Title:
                                               ---------------------------------

PLEASE FAX A COPY OF THE COMPLETED AND EXECUTED NOTICE AND QUESTIONNAIRE, AND
RETURN THE ORIGINAL BY OVERNIGHT MAIL, TO:

                       Rockwell Medical Technologies, Inc.
                                30142 Wixom Road
                                 Wixom, MI 48393
               Attention: Robert Chioini, Chief Executive Officer


                                       21