U.S. SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549
                                 FORM 12b-25

                                                 Commission File Number 0-25353

                          NOTIFICATION OF LATE FILING

(Check One) _X_ Form 10-K  __ Form 20-F __ Form 11-K  __ Form 10-Q __ Form N-SAR

For Period Ended:   September 30, 2002
                    -----------------------------------

                 [  ]     Transition Report on Form 10-K
                 [  ]     Transition Report on Form 20-F
                 [  ]     Transition Report on Form 11-K
                 [  ]     Transition Report on Form 10-Q
                 [  ]     Transition Report on Form N-SAR

For the Transition Period Ended:
                                  -----------------------------


     Nothing in the form shall be construed to imply that the Commission has
verified any information contained herein.

     If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:


                        PART I - REGISTRANT INFORMATION

Full name of registrant:     Demegen, Inc.
                         -------------------------------------------------------

Former name if applicable:   Demeter Biotechnologies, Inc.
                           -----------------------------------------------------

Address of principal executive office (Street and number):   1051 Brinton Road
                                                            --------------------

City, State and Zip Code:   Pittsburgh, PA 15221
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                       PART II - RULES 12b-25(b) and (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following
should be completed.  (Check appropriate box)

[ ]      (a)     The reasons described in reasonable detail in Part III of this
                 form could not be eliminated without unreasonable effort or
                 expense;

[X]      (b)     The subject annual report, semi-annual report, transition
                 report on Form 10-K, 20-F, 11-K, Form N-SAR, or portion
                 thereof, will be filed on or before the 15th calendar day
                 following the prescribed due date; or the subject quarterly
                 report or transition report on Form 10-Q, or portion thereof
                 will be filed on or before the fifth calendar day following
                 the prescribed due date; and

[ ]      (c)     The accountant's statement or other exhibit required by Rule
                 12b-25(c) has been attached if applicable.

                              PART III - NARRATIVE

State below in reasonable detail the reasons why the Form 10-K, and Form 10-KSB,
11-K, 20-F, 10-Q, Form 10-QSB,  N-SAR, or the transition report or portion
thereof, could not be filed with the prescribed time period. (Attach extra
sheets if needed.)

The registrant has curtailed operations which has slowed the audit process. The
registrant expects that the financial statements will be filed within the
15-day extension period.


                          PART IV - OTHER INFORMATION

(1)      Name and telephone number of person to contact in regard to this
         notification

         Richard D. Ekstrom             412                       241-2150
         ------------------      ------------------            --------------
              (Name)                (Area Code)              (Telephone Number)

(2)      Have all other periodic reports required under Section 13 or 15(d) of
         the Securities Exchange Act of 1934 or Section 30 of the Investment
         Company Act of 1940 during the preceding 12 months or for such
         shorter period that the registrant was required to file such report(s)
         been filed? If the answer is no, identify report(s).

                                 [X] Yes [ ] No

(3)      Is it anticipated that any significant change in results of operations
         from the corresponding period for the last fiscal year will be
         reflected by the earnings statements to be included in the subject
         report or portion thereof?

                                 [ ] Yes [X] No

     If so, attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results cannot be made.


                                 Demegen, Inc.
                  --------------------------------------------
                  (Name of Registrant as specified in charter)

Has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.

Date: 12/27/02                     By /s/ Richard D. Ekstrom
                                      ---------------------------
                                      Name: Richard D. Ekstrom
                                      Title: Chairman & Chief Executive Officer