Exhibit 32.1


                CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350
      AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


In connection with the Annual Report of WesBanco, Inc on Form 10-K for the
period ended December 31, 2003 as filed with the Securities and Exchange
Commission on the date hereof (the "Report"), the undersigned, in the capacity
and on the date indicated below, hereby certifies pursuant to 18 U.S.C. Section
1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that
to his knowledge:

     1.   The Report fully complies with the requirements of Section 13(a) or
          15(d) of the Securities Exchange Act of 1934; and

     2.   The information contained in the Report fairly presents, in all
          material respects, the financial condition and results of operation of
          WesBanco, Inc.


           Date: March 15, 2004           /s/ Paul M. Limbert
                                          ------------------------------------
                                          Paul M. Limbert
                                          President and Chief Executive Officer


           Date: March 15, 2004           /s/ Robert H. Young
                                          ------------------------------------
                                          Robert H. Young
                                          Executive Vice President and Chief
                                          Financial Officer



The forgoing certifications are being furnished solely pursuant to Subsections
(a) and (b) of Section 1350, Chapter 63 of Title 18, United States Code in
accordance with Section 906 of the Sarbanes-Oxley Act of 2002 and shall not be
deemed "filed" for purposes of Section 18 of the Securities Exchange Act of
1934, or otherwise subject to the liability of that section, and shall not be
deemed to be incorporated by reference into any filing under the Securities Act
of 1933 or the Securities Exchange Act of 1934.

A signed original of this written statement required by Section 906 of the
Sarbanes-Oxley Act of 2002, or other document authenticating, acknowledging, or
otherwise adopting the signature that appears in typed form within the
electronic version of this written statement required by Section 906, has been
provided to the Corporation and will be retained by the Corporation and
furnished to the Securities and Exchange Commission or its staff upon request.


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