Exhibit 23.1 CONSENT OF INDEPENDENT AUDITORS The Board of Directors ICOS-Texas Biotechnology L.P.: We consent to the incorporation by reference in the registration statements (Nos. 33-79656, 33-79658, 33-79670, 33-93282, 33-93368, 333-27423, 333-27425, 333-79477, 333-72468 and 333-41864) on Form S-8 and (Nos. 333-03433 and 333-25043) on Form S-3 of Texas Biotechnology Corporation of our report dated January 23, 2002, with respect to the balance sheets of ICOS-Texas Biotechnology L.P. (a development stage limited partnership) as of December 31, 2001 and 2000, and the related statements of operations, partners' deficit and cash flows for the year ended December 31, 2001, the period from June 6, 2000 (inception) to December 31, 2000, and the period from June 6, 2000 (inception) to December 31, 2001, which report appears in the December 31, 2001 annual report on Form 10-K/A of Texas Biotechnology Corporation. Our report on ICOS-Texas Biotechnology L.P. dated January 23, 2002, contains an explanatory paragraph that states that ICOS-Texas Biotechnology L.P. has experienced recurring losses from operations and has a partners' deficit which raise substantial doubt about its ability to continue as a going concern. The ICOS-Texas Biotechnology L.P. financial statements do not include any adjustments that might result from the outcome of that uncertainty. /s/ KPMG LLP KPMG LLP Seattle, Washington July 8, 2002