EXHIBIT 99.2

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                       AS ADOPTED PURSUANT TO SECTION 906
                        OF THE SARBANES-OXLEY ACT OF 2002

      In connection with the Quarterly Report of Texas Biotechnology Corporation
(the "Company") on Form 10-Q for the period ending June 30, 2002 (the "Report"),
as filed with the Securities and Exchange Commission on the date hereof, I,
Stephen L. Mueller, Vice President, Finance & Administration of the Company,
certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, that:

      1. The Report fully complies with the requirements of section 13(a) or
15(d) of the Securities Exchange Act of 1934, as amended; and

      2. The information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations of the
Company.


/s/ STEPHEN L. MUELLER
- ----------------------------------------
Stephen L. Mueller
Vice President, Finance & Administration

August 14, 2002