EXHIBIT 32.1


                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of Isolagen, Inc. (the "Company") on
Form 10-Q for the fiscal quarter ended September 30, 2003 as filed with the
Securities and Exchange Commission on the date hereof (the "Report"), I, Michael
Macaluso, Chief Executive Officer of the Company, hereby certify, pursuant to 18
U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley
Act of 2002, that:

         o        The Report fully complies with the requirements of section
                  13(a) or 15(d) of the Securities Exchange Act of 1934 (15
                  U.S.C 78m or 78o(d)); and

         o        The information contained in the Report fairly presents, in
                  all material respects, the financial condition and results of
                  operations of the Company.

Date: November 18, 2003             By: /s/ Michael Macaluso
                                    --------------------------------------
                                    Michael Macaluso, CEO

A signed original of this written statement required by Section 906 has been
provided to Isolagen, Inc. and will be retained by Isolagen, Inc. and furnished
to the Securities and Exchange Commission or its staff upon request.