1 EXHIBIT 11 TEXAS BIOTECHNOLOGY CORPORATION COMPUTATION OF PER SHARE EARNINGS (LOSS) PRIMARY COMPUTATION (UNAUDITED) THREE MONTHS ENDED NINE MONTHS ENDED SEPTEMBER 30, SEPTEMBER 30, 1997 1996 1997 1996 ----------- ------------ ------------ ------------- Net income (loss) $ 4,119,662 $ (5,630,084) $ (6,821,769) $ (15,982,377) Applicable common and common stock equivalent shares: Weighted average shares of common stock outstanding during the period 26,261,020 24,188,708 25,853,961 23,053,607 Incremental number of shares outstanding during the period resulting from the assumed exercises of stock options 678,573 -- -- -- Incremental number of shares outstanding during the period resulting from the assumed exercises of warrants 366,362 -- -- -- ----------- ------------ ------------ ------------- Weighted average shares of common stock and common stock equivalents outstanding during the period 27,305,955 24,188,708 25,853,961 23,053,607 =========== ============ ============ ============ Net income (loss) per common share, primary $ 0.15 $ (0.23) $ (0.26) $ (0.69) =========== ============ ============ ============ Note: For the three months ended September 30, 1996 and the nine months ended September 30, 1996 and 1997, shares related to the exercise of stock options and warrants are not considered as their effect would be antidilutive. 2 EXHIBIT 11 TEXAS BIOTECHNOLOGY CORPORATION COMPUTATION OF PER SHARE EARNINGS FULLY DILUTED COMPUTATION (UNAUDITED) THREE MONTHS ENDED NINE MONTHS ENDED SEPTEMBER 30, SEPTEMBER 30, 1997 1996 1997 1996 ----------- ----------- ----------- ----------- Net income before preferred dividend requirement $ 4,416,891 N/A N/A N/A Applicable common and common stock equivalent shares: Weighted average shares of common stock outstanding during the period 26,261,020 Incremental number of shares outstanding during the period resulting from the assumed exercises of stock options 769,469 Incremental number of shares outstanding during the period resulting from the assumed exercises of warrants 438,318 Incremental number of shares outstanding during the period resulting from the assumed conversion of preferred stock 1,008,351 Incremental number of shares outstanding during the period resulting from the assumed issuance of contingent stock 285,715 ----------- ----------- ----------- ----------- Weighted average shares of common stock and common stock equivalents outstanding during the period 28,762,873 -- -- -- =========== =========== =========== =========== Net income per common share, fully diluted $ 0.15 N/A N/A N/A =========== =========== =========== ===========