Exhibit 10.8

                         PHARMACEUTICAL RESOURCES, INC.

                                   Guarantee
                                   ---------


          The undersigned, being directly or indirectly, the beneficial owner of
PRI-Research, Inc., a Delaware corporation ("PRI-Research"), in order to induce
C.T.P. Research and Development (1995) Ltd., an Israeli private company limited
by shares ("C.T.P."), to enter into that certain Limited Partnership Agreement
(the "Agreement") of Clal Pharmaceutical Resources L.P. (the "Partnership"),
dated May 1, 1995, among Clal Pharmaceutical Resources (1995) Ltd. (the "General
Partner"), C.T.P. and PRI-Research, does hereby unconditionally guarantee the
full and timely performance of PRI-Research's obligations to the Partnership,
the General Partner and C.T.P. under the Agreement, if, and only to the extent
to which, PRI-Research shall be required to perform such obligations.  In
connection herewith, the undersigned shall be entitled to avail itself of and to
assert any rights, claims or defenses otherwise available to PRI-Research with
respect to such obligations.  This Guarantee is being delivered by the
undersigned to the Partnership, the General Partner and C.T.P. in connection
with the execution and delivery of the Agreement.

          The undersigned hereby represents and warrants that it is a
corporation duly organized, validly existing and in good standing under the laws
of the State of New Jersey.  The undersigned hereby further represents and
warrants that it has all necessary corporate power and authority to execute,
deliver and perform this Guarantee, that the execution, delivery and performance
by the undersigned of this Guarantee has been duly authorized by all necessary
corporate or other action by or on behalf of the undersigned and that this
Guarantee constitutes a valid and binding obligation of the undersigned,
enforceable against the undersigned in accordance with its terms.

          This Guarantee shall be governed by and construed in accordance with
the laws of the State of New York without regard to the choice-of-law provisions
thereof.


Dated:  May 1, 1995

                              PHARMACEUTICAL RESOURCES, INC.


                              By: /s/ Kenneth I. Sawyer
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