SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 -------------------- FORM 10-Q [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 1995 OR [_] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 0-18311 NEUROGEN CORPORATION (Exact name of registrant as specified in its charter) Delaware 22-2845714 (State or other jurisdiction of (I.R.S. Employer incorporation or organization) Identification No.) 35 Northeast Industrial Road Branford, Connecticut 06405 (Address of principal executive offices) (Zip Code) (203) 488-8201 (Registrant's telephone number, including area code) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes X No - --- As of November 13, 1995, the registrant had 13,077,491 shares of Common Stock outstanding. NEUROGEN CORPORATION INDEX Page Number ------ Part I - Financial Information Item 1. Financial Statements........................................... 1 Balance Sheets at September 30, 1995 and December 31, 1994.............................................. 1,2 Statements of Operations and Accumulated Deficit for the three- month periods ended September 30, 1995 and 1994 and for the nine-month periods ended September 30, 1995 and 1994.......... 3 Statements of Cash Flows for the nine-month periods ended September 30, 1995 and 1994.................................... 4 Notes to Financial Statements.................................. 5-6 Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations.......................................... 7-11 Part II - Other Information Item 1. Legal Proceedings............................................ 11 Item 2. Changes in Securities........................................ 11 Item 3. Defaults upon Senior Securities.............................. 11 Item 4. Submission of Matters to a Vote of Security Holders.......... 11 Item 5. Other Information............................................ 12 Item 6. Exhibits and Reports on Form 8-K............................. 12 Signature ............................................................. 13 Part I - Financial Information 9/95 10 - Q Balance Sheet Item 1 - Financial Statements NEUROGEN CORPORATION BALANCE SHEETS SEPTEMBER 30, DECEMBER 31, 1995 1994 (UNAUDITED) (AUDITED) ----------- --------- ASSETS Current assets: Cash and cash equivalents $65,957,934 $ 9,439,727 Marketable securities 6,374,723 6,040,434 Other current assets 699,863 398,542 ----------- ----------- Total current assets 73,032,520 15,878,703 Property, plant & equipment: Land 425,000 425,000 Building 8,406,633 8,379,703 Equipment 3,382,666 2,297,728 Furniture 143,377 110,668 Equipment and furniture under capital lease - 1,200,000 ----------- ----------- 12,357,676 12,413,099 Less accumulated depreciation 1,918,312 2,588,476 ----------- ----------- Net property, plant and equipment 10,439,364 9,824,623 Other assets, net 359,339 185,752 ----------- ----------- $83,831,223 $25,889,078 =========== =========== See accompanying notes to financial statements. 1 Item 1 - Financial Statements Neurogen Corporation Balance Sheets September 30, December 31, 1995 1994 (Unaudited) (Audited) ------------- ------------ Liabilities & Stockholders' Equity Current Liabilities: Accrued expenses $ 1,710,283 $ 949,717 Unearned revenue from collaborative partner 4,494,667 - Current portion of mortgage payable 154,920 141,125 Current portion of capital lease obligation - 30,863 ------------ ------------ Total current liabilities 6,359,870 1,121,705 Mortgage payable, excluding current portion 501,909 619,887 Other compensation 62,587 62,587 Deferred gain on sale of assets - 4,375 ------------ ------------ Total liabilities 6,924,366 1,808,554 Stockholders' Equity: Preferred stock, par value $.025 per share. Authorized 2,000,000 shares; none issued - - Common stock, par value $.025 per share. Authorized 30,000,000 shares; issued and outstanding 13,033,233 shares at September 30, 1995 and 10,082,763 shares at December 31, 1994 325,831 252,069 Additional paid-in capital 88,777,100 45,607,590 Accumulated deficit (12,272,079) (21,766,182) Unrealized gain (loss) on marketable securities 76,005 (12,953) ------------ ------------ Total stockholders' equity 76,906,857 24,080,524 $ 83,831,223 $ 25,889,078 ============ ============ See accompanying notes to financial statements. 2 Neurogen Corporation Statements of Operations and Accumulated Deficit Three Months Three Months Nine Months Nine Months Ended Ended Ended Ended Sept. 30, 1995 Sept. 30, 1994 Sept. 30, 1995 Sept. 30, 1994 (Unaudited) (Unaudited) (Unaudited) (Unaudited) -------------- -------------- -------------- -------------- Operating revenues: License fees $ - $ - $ 14,000,000 $ - Research revenue 2,644,667 1,744,667 6,384,000 4,044,667 ------------ ------------ ------------ ------------ Total operating revenues 2,644,667 1,744,667 20,384,000 4,044,667 Operating Expenses: Research & development 3,660,341 3,024,952 9,550,032 7,368,601 General & administrative 654,453 546,764 2,160,755 2,172,915 ------------ ------------ ------------ ------------ Total operating expenses 4,314,794 3,571,716 11,710,787 9,541,516 Other income (expense): Investment income 647,436 179,957 1,100,906 332,546 Interest expense (17,020) (21,885) (53,016) (69,942) ------------ ------------ ------------ ------------ Total other income, net 630,416 158,072 1,047,890 262,604 Net income (loss) before provision for income taxes $ (1,039,711) $ (1,668,977) $ 9,721,103 $ (5,234,245) Provision for income taxes - - $ 227,000 - ------------ ------------ ------------ ------------ Net income (loss) $ (1,039,711) $ (1,668,977) $ 9,494,103 $ (5,234,245) ------------ ------------ ------------ ------------ Earnings (loss) per share: Primary $ (0.09) $ (0.17) $ 0.82 $ (0.56) ============ ============ ============ ============ Fully diluted $ - $ - $ 0.79 $ - ============ ============ ============ ============ Shares used in calculation of earnings (loss) per share: Primary 11,359,000 10,080,000 11,600,000 9,346,000 ============ ============ ============ ============ Fully diluted - - 12,056,000 - ============ ============ ============ ============ Accumulated deficit: Beginning of period $(11,232,368) $(18,680,255) $(21,766,182) $(15,114,987) ------------ ------------ ------------ ------------ End of period $(12,272,079) $(20,349,232) $(12,272,079) $(20,349,232) ============ ============ ============ ============ See accompanying notes to financial statements. 3 Neurogen Corporation 9/95 10 - Q Cash Flow Statements of Cash Flows Nine Months Nine Months Ended Sept. 30, Ended Sept. 30, 1995 1994 (Unaudited) (Unaudited) --------------- --------------- Cash flows from operating activities: Net income (loss) $ 9,494,103 $ (5,234,245) Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: Depreciation and amortization expense 547,615 651,596 Unrealized loss on marketable securities - 76,209 Net loss (gain) on sale of assets 3,053 (16,652) Changes in operating assets and liabilities: Increase in accrued expenses 760,561 189,856 Increase in unearned revenue from collaborative partner 4,494,667 594,667 Increase in other current assets (301,322) (251,733) Increase in other assets, net (185,795) (64,164) ------------- ------------ Net cash provided by (used in) operating activities 14,812,882 (4,054,466) ------------- ------------ Cash flows from investing activities: Purchase of plant and equipment (1,157,576) (461,938) Purchases of marketable securities (16,647,511) (11,732,864) Sales of marketable securities 16,402,180 11,560,469 ------------- ------------ Net cash used in investing activities (1,402,907) (634,333) ------------- ------------ Cash flows from financing activities: Exercise of employee stock options 354,677 - Exercise of warrants - 90,000 Proceeds from sale of common stock, net 42,888,595 9,864,000 Principal payments under mortgage payable (104,182) (91,999) Principal payments under capital lease obligations (30,858) (257,891) ------------- ------------ Net cash provided by financing activities 43,108,232 9,604,110 ------------- ------------ Net increase in cash and cash equivalents equivalents 56,518,207 4,915,311 Cash and cash equivalents at beginning of period 9,439,727 6,403,987 ------------- ------------ Cash and cash equivalents at end of period $ 65,957,934 $ 11,319,298 ============= ============ See accompanying notes to financial statements. 4 NEUROGEN CORPORATION NOTES TO FINANCIAL STATEMENTS SEPTEMBER 30, 1995 (UNAUDITED) (1) Basis of Presentation and Summary of Significant Accounting Policies -------------------------------------------------------------------- The unaudited financial statements have been prepared from the books and records of Neurogen Corporation (the "Company") in accordance with generally accepted accounting principles for interim financial information pursuant to Rule 10-01 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. Interim results are not necessarily indicative of the results that may be expected for the fiscal year. (2) Public Offering --------------- In August 1995, the Company completed the issuance of an additional 2,875,000 shares of common stock through an underwritten public offering which resulted in net proceeds of $42,888,595. (3) Lease of Additional Facilities ------------------------------ In the third quarter, the Company entered into a ten year lease agreement to lease 24,000 square feet of space in a building adjacent to the Company's existing research facility. The Company has a renewal option to extend the lease for an additional ten year period and an additional option to purchase the building after the sixth year of the lease. The Company anticipates that the renovation of the leased facility into laboratory and office space will be completed by or near the end of 1996. Future minimum rental lease payments for the five years subsequent to September 30, 1995 are: 1996 $ 126,000 1997 $ 126,000 1998 $ 126,000 1999 $ 126,000 2000 $ 126,000 Thereafter $ 756,000 ---------- Total minimum lease payments $1,386,000 (4) Subsequent Event ---------------- On November 6, 1995, the Company announced that it had reached an agreement in principle with Pfizer Inc ("Pfizer") on a new collaboration to develop and commercialize drugs for the treatment of obesity and eating disorders. Under the terms of the proposed agreement, Pfizer will purchase 750,000 shares of common stock for $16,500,000 at a price of $22.00 per share and pay Neurogen $3.5 million as a license fee. In addition Pfizer will fund a three year research program with an option to 5 extend for two additional years at the rate of $2.4 million per year and will also pay milestones of up to approximately $28 million on collaboration drugs as they proceed through clinical development. Neurogen can earn a portion of the profit, if any, generated by sales of collaboration drugs in the North American Free Trade Agreement (NAFTA) countries by funding a portion of the cost of clinical trials and marketing in these countries. If Neurogen chooses not to exercise the profit-sharing option, Pfizer will pay Neurogen royalties on any marketed drugs in NAFTA countries. Pfizer will pay royalties on any marketed drugs in non-NAFTA countries under either scenario. 6 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS Since its inception in September 1987, Neurogen has been engaged in the discovery and development of proprietary therapeutic products for the treatment of psychiatric and neurological disorders. The Company has not derived any revenue from product sales and, excluding the effect of $14 million in one-time license fees received from Schering-Plough Corporation ("Schering-Plough") in 1995, expects to incur significant losses over at least the next several years. Its revenues to date have come from two collaborative agreements with Pfizer Inc. ("Pfizer"), one collaboration with Schering-Plough and from investment income. The Company and Pfizer entered into certain agreements dated as of January 1, 1992 (the "1992 Pfizer Agreement") to develop drugs for anxiety and cognition disorders. Neurogen and Pfizer entered into additional agreements dated as of July 1, 1994 (the "1994 Pfizer Agreement" and together with the 1992 Pfizer Agreement, the "Pfizer Agreements") to develop drugs to treat sleep disorders. In June 1995, Neurogen and Schering-Plough entered into agreements to develop drugs for the treatment of schizophrenia and other disorders which act through the dopamine family of receptors and to allow Schering-Plough to screen certain libraries of compounds from Neurogen's combinatorial chemistry program (the "Schering-Plough Agreement"). RESULTS OF OPERATIONS Results of operations may vary from period to period depending on numerous factors, including the timing of income earned under existing or future strategic alliances, joint ventures or financings, if any, the progress of the Company's research and development projects, technological advances and determinations as to the commercial potential of proposed products. Neurogen expects research and development costs to increase significantly over the next several years as its drug development programs progress. In addition, general and administrative expenses necessary to support the expanded research and development activities are expected to increase for the foreseeable future. THREE MONTHS ENDED SEPTEMBER 30, 1995 AND 1994 The Company's operating revenues were $2.64 million for the three months ended September 30, 1995 compared to $1.74 million for the same period in 1994. This increase is due to the commencement of the research program under the Schering-Plough Agreement in the third quarter of 1995. Research funding pursuant to the Pfizer Agreements and Schering-Plough Agreement constituted all of the Company's research revenues and increased 52% for the three-month period ended September 30, 1995 compared to the same period in 1994. Research and development costs have increased $635,000 or 21%, to $3.66 million for the three-month period ended September 30, 1995 as compared to the same period in 1994. This increase is due primarily to expansion of preclinical and clinical testing on the Company's lead eating disorders compound and increased staffing levels. Research and development costs represented 85% of total operating expenses in the third quarters of both 1995 and 1994. 7 General and administrative expenses increased $108,000 or 20%, for the three-month period ended September 30, 1995 as compared to the same period in 1994. This increase is primarily attributable to a refinement in the Company's allocation of expenses between general and administrative and research and development. Other income (net), consisting primarily of interest income and net gains from U.S. government securities, increased 299% for the third quarter of 1995 compared to the same period in 1994 due primarily to a higher level of invested funds. The Company incurred a net loss of $1.04 million for the three months ended September 30, 1995, as compared with a net loss of $1.67 million for the same period in 1994. The decrease in the net loss in 1995 is primarily due to the commencement of the research program under the Schering-Plough Agreement in July 1995 and the increase in interest earnings noted above, offset in part by the increase in operating expenses noted above. NINE MONTHS ENDED SEPTEMBER 30, 1995 AND 1994 In June 1995, the Company received, and recognized as revenue, $14 million in one-time license fees from Schering-Plough in connection with entering into the Schering-Plough Agreement. The Company's operating revenues were $20.38 million for the nine months ended September 30, 1995, compared to $4.04 million for the same period in 1994. This increase is due primarily to the above-referenced $14.0 million in one-time license fees. In addition, research revenues increased from $4.04 million to $6.38 million for the nine-month period ended September 30, 1995, an increase of 58%, due to the commencement of the 1994 Pfizer Agreement in the third quarter of 1994 and the Schering-Plough Agreement in the third quarter of 1995. Research and development costs have increased $2.18 million, or 30%, to $9.55 million for the nine-month period ended September 30, 1995 as compared to the same period in 1994. This increase is due primarily to expansion of preclinical and clinical testing on the Company's lead schizophrenia and eating disorders compounds and increased staffing levels. Research and development costs represented 82% of total operating expenses for the first nine months of 1995 as compared to 77% for the same period in 1994. General and administrative expenses during the nine month period ended September 30, 1995 were unchanged as compared to the same period in 1994. Other income (net), consisting primarily of interest income, and net gains from U.S. government securities, increased $785,000 or 299% for the first nine months of 1995 compared to the same period in 1994 due primarily to a higher level of invested funds. 8 The Company recognized net income of $9.49 million for the nine- month period ended September 30, 1995 as compared with a net loss of $5.23 million for the same period in 1994. The change in earnings is primarily due to the one-time license fees of $14 million from Schering-Plough and the above noted increases in research revenue and interest income offset in part by increases in operating expenses. In 1994, the Company adopted Financial Accounting Standards Board Statement No. 115, "Accounting for Certain Investments in Debt and Equity Securities" ("SFAS 115"). Adoption of SFAS 115 did not have a significant impact on the Company's financial statements. LIQUIDITY AND CAPITAL RESOURCES At September 30, 1995 and December 31, 1994, cash, cash equivalents and marketable securities were in the aggregate $72.33 million and $15.48 million, respectively. The increase in 1995 was primarily due to net proceeds of $42.89 million received from the sale of 2,875,000 of common stock to the public and $17 million (including $3 million of unearned revenue) received from Schering-Plough in connection with entering into the Schering-Plough Agreement. The Company's aggregate level of cash, cash equivalents and marketable securities have fluctuated in the past and are expected to fluctuate in the future as a result of the factors described below. Neurogen's cash requirements to date have been met by the proceeds of its financing activities, amounts received pursuant to the Pfizer Agreements and the Schering-Plough Agreement and interest earned on invested funds. The Company's financing activities include three private placement offerings of the Company's common stock during 1988 and 1989, a public offering of the Company's common stock in each of 1989, 1991 and 1995, and the private sale of common stock to Pfizer in connection with entering into the Pfizer Agreements. Total funding received from these financing activities was approximately $88.3 million. The Company's expenditures have been primarily to fund research and development and general and administrative expenses. In the first quarter of 1992, the Company entered into the 1992 Pfizer Agreement pursuant to which Pfizer made a $13.8 million equity investment in the Company. Under such agreement, the Company has received or is scheduled to receive $4.6 million in each of 1992, 1993, 1994 and 1995 to fund Neurogen's research in its anxiolytic (anxiety-reducing drugs) and cognitive enhancer programs. In addition, Neurogen and Pfizer agreed in October 1995 to extend this research collaboration through 1996. Under the terms of this extension, Neurogen will receive another $4.6 million during 1996 and the parties expect to focus the resources of this collaborative effort primarily on Neurogen's sleep disorder program. Neurogen could also receive milestone payments of up to $12.5 million during the development and regulatory approval of its anxiolytic and cognition enhancement products. In return, Pfizer received the exclusive rights to manufacture and market anxiolytics and cognition enhancers that act through the family of receptors which interact with the neuro-transmitter gama-aminobutyric acid, or GABA, and for which it will pay Neurogen royalties based upon net sales levels, if any, for such products. As of September 30, 1995, Pfizer had provided $17.3 million of research 9 funding to the Company pursuant to the 1992 Pfizer Agreement, in addition to its equity investment in 1992. Neurogen and Pfizer entered into their second collaborative agreement, the 1994 Pfizer Agreement, in July 1994, pursuant to which Pfizer provided $9.9 million in equity financing. Under such agreement, the Company has received or is scheduled to receive approximately $7.4 million during the three-year period which commenced July 1, 1994, to fund Neurogen's research in its sleep disorder program and may receive up to an additional $2.4 million for a fourth year should Pfizer exercise its option to extend the collaboration. Neurogen could also receive milestone payments of up to $3.3 million during the development and regulatory approval of its sleep disorder compounds. As part of this second collaboration, Pfizer received the exclusive rights to manufacture and market GABA-based sleep disorder products for which it will pay Neurogen royalties depending upon net sales levels, if any. As of September 30, 1995, Pfizer had provided $3.8 million of research funding to the Company pursuant to the 1994 Pfizer Agreement, in addition to its equity investment in 1994. Under both the 1992 Pfizer Agreement and the 1994 Pfizer Agreement, in addition to making the equity investments and the research and milestone payments noted above, Pfizer is responsible for funding the cost of all clinical development and marketing, if any, of drugs developed from the collaboration. In June 1995, Neurogen and Schering-Plough entered into the Schering-Plough Agreement pursuant to which Neurogen and Schering-Plough are collaborating in the discovery and development of drugs for the treatment of schizophrenia and other disorders which act through the dopamine family of receptors. Pursuant to the Schering-Plough Agreement, the Company received one-time license fees of $14 million for the rights to Neurogen's dopamine compounds and $3 million for the right to test certain of Neurogen's combinatorial chemistry libraries in selected non-CNS assays. Schering-Plough also agreed to pay an additional $3 million in 1996 for the right to test additional libraries. Neurogen expects to receive approximately $7.2 million during the two-year period which commenced June 28, 1995, of which $1.8 million had been paid as of September 30, 1995, for research and development funding of the Company's schizophrenia program. The Company may receive additional research and development funding of up to $3.6 million per year for three additional one-year periods depending on whether and the extent to which Schering-Plough exercises its right to extend the collaboration. Neurogen could also receive milestone payments of up to approximately $32 million if it achieves certain development and regulatory objectives regarding its products subject to the collaboration. In return, Schering-Plough received the exclusive worldwide license to market products subject to the collaboration and 10 Neurogen retained the rights to receive royalties based on net sales levels, if any. On November 6, 1995, the Company announced that it had reached an agreement in principle with Pfizer Inc ("Pfizer") on a new collaboration to develop and commercialize drugs for the treatment of obesity and eating disorders. Under the terms of the proposed agreement, Pfizer will purchase 750,000 shares of common stock for $16,500,000 at a price of $22.00 per share and pay Neurogen $3.5 million as a license fee. In addition Pfizer will fund a three year research program with an option to extend for two additional years at the rate of $2.4 million per year and will also pay milestones of up to approximately $28 million on collaboration drugs as they proceed through clinical development. Neurogen can earn a portion of the profit, if any, generated by sales of collaboration drugs in the North American Free Trade Agreement (NAFTA) countries by funding a portion of the cost of clinical trials and marketing in these countries. If Neurogen chooses not to exercise the profit-sharing option, Pfizer will pay Neurogen royalties on any marketed drugs in NAFTA countries. Pfizer will pay royalties on any marketed drugs in non-NAFTA countries under either scenario. The Company plans to use its cash balance for its research and development activities, working capital and general corporate purposes. Neurogen anticipates that its current cash balance (excluding the anticipated proceeds and effect of the proposed eating disorders collaboration noted above), as supplemented by research funding pursuant to the Pfizer Agreements and the Schering-Plough Agreement, will be sufficient to fund its current and planned operations through 1998. However, Neurogen's funding requirements may change and will depend upon numerous factors, including but not limited to, the progress of the Company's research and development programs, the timing and results of preclinical testing and clinical studies, the timing of regulatory approvals, technological advances, determinations as to the commercial potential of its proposed products, the status of competitive products and the ability of the Company to establish and maintain collaborative arrangements with others for the purpose of funding certain research and development programs, conducting clinical studies, obtaining regulatory approvals and, if such approvals are obtained, manufacturing and marketing products. The Company anticipates that it may augment its cash balance through financing transactions, including the issuance of debt or equity securities and further corporate alliances. No arrangements have been entered into for any future financing and no assurances can be given that adequate levels of additional funding can be obtained on favorable terms, if at all. As of December 31, 1994, for federal income tax purposes, the Company had generated net operating loss carryforwards of approximately $22.8 million, which are scheduled to expire in the years 2003 through 2009. A significant portion of these net operating loss carryforwards will be utilized in 1995 as a result, in part, of one-time payments received and corresponding revenues recognized pursuant to the Schering-Plough Agreement. Future issuance of securities by the Company and/or sales of securities by the Company's principal shareholders could result in an ownership change as defined by Section 382 of the Internal Revenue Code of 1986. Such an ownership change could limit the Company's utilization of net operating loss carryforwards to offset future taxable income, if any. 11 PART II - OTHER INFORMATION ITEM 1. LEGAL PROCEEDINGS Not applicable for the quarter ended September 30, 1995. ITEM 2. CHANGES IN SECURITIES Not applicable for the quarter ended September 30, 1995. ITEM 3. DEFAULTS UPON SENIOR SECURITIES Not applicable for the quarter ended September 30, 1995. ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS Not applicable for the quarter ended September 30, 1995. ITEM 5. OTHER INFORMATION Not applicable for the quarter ended September 30, 1995. ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K On July 28, 1995, the Company filed a copy of the Schering-Plough Agreement (with certain confidential portions deleted) on Form 8-K. On August 16, 1995, the Company refiled a copy of the Schering-Plough Agreement (with certain revised confidential portions deleted) on Form 8-KA. The Company made no other filings on Form 8-K during the quarter ended September 30, 1995. Signature Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. NEUROGEN CORPORATION By:/s/ STEPHEN R. DAVIS ---------------- Stephen R. Davis Vice President-Finance and Chief Financial Officer Date: November 13, 1995 Exhibit Index ------------- Exhibit ------- Number ------ 10.1 - Neurogen Corporation Stock Option Plan, as amended (incorporated by reference to Exhibit 10.1 to the Company's Form 10-K for the fiscal year ended December 31, 1991). 10.2 - Form of Stock Option Agreement currently used in connection with the grant of options under Neurogen Corporation Stock Option Plan (incorporated by reference to Exhibit 10.2 to the Company's Form 10-K for the fiscal year ended December 31, 1992). 10.3 - Neurogen Corporation 1993 Omnibus Incentive Plan, as amended (incorporated by reference to Exhibit 10.3 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.4 - Form of Stock Option Agreement currently used in connection with the grant of options under Neurogen Corporation 1993 Omnibus Incentive Plan (incorporated by reference of Exhibit 10.4 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.5 - Neurogen Corporation 1993 Non-Employee Directors Stock Option Program (incorporated by reference to Exhibit 10.5 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.6 - Form of Stock Option Agreement currently used in connection with the grant of options under Neurogen Corporation 1993 Non-Employee Directors Stock Option Program (incorporated by reference to Exhibit 10.6 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.7 - Employment Contract between the Company and Harry H. Penner, Jr., dated as of October 12, 1993 (incorporated by reference to Exhibit 10.7 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.8 - Employment Contract between the Company and John F. Tallman, dated as of December 1, 1993 (incorporated by reference to Exhibit 10.25 the Company's Form 10-G for the quarterly period ended September 30, 1994). 10.9 - Open-End Mortgage Deed and Security Agreement between the Company and Orion Machinery & Engineering Corp., dated March 16, 1989 (incorporated by reference to Exhibit 10.15 to Registration Statement No. 33-29709 on Form S-1). 10.10 - Construction Agreement between the Company and Frank E. Downes Construction Company, Inc., dated August 25, 1992 (incorporated by reference to Exhibit 10.17 to the Company's Form 10-K for the fiscal year ended December 31, 1992). 10.11 - Letter Agreement between the Company and Biotechnology Venture Fund S.A., dated August 5, 1988 (incorporated by reference to Exhibit 10.26 to Registration Statement No. 33-29709 on Form S- 1). 10.12 - Letter Agreement between the Company and Biotechnology Venture Fund S.A., dated February 5, 1989 (incorporated by reference to Exhibit 10.27 to Registration Statement No. 33-29709 on Form S- 1). 10.13 - Letter Agreement between David Blech and Peter McPartland, dated February 17, 1989 (incorporated by reference to Exhibit 10.28 to Registration Statement No. 33-29709 on Form S-1). 10.14 - Letter Agreement between David Blech and Isaac Blech and Michael Drew, dated February 21, 1989 (incorporated by reference to Exhibit 10.29 to Registration Statement No. 33-29709 on Form S- 1). 10.15 - Letter Agreement between the Company and Schroder International Trust Co., Ltd., dated February 24, 1989 (incorporated by reference to Exhibit 10.30 to Registration Statement No. 33-29709 on Form S-1). 10.16 - Form of Proprietary Information and Inventions Agreement (incorporated by reference to Exhibit 10.31 to Registration Statement No. 33-29709 on Form S-1). 10.17 - Warrant to Purchase 47,058 Shares of Common Stock to MMC/GATX Partnership No. I, dated February 20, 1991 (incorporated by reference to Exhibit 10.34 to the Company's Form 10-K for the fiscal year ended December 31, 1990). 10.18 - Collaborative Research Agreement between the Company and Pfizer Inc, dated as of January 1, 1992 (incorporated by reference to Exhibit 10.35 to the Company's Form 10-K for the fiscal year ended December 31, 1991). 10.19 - License Agreement between the Company and the National Technical Information Service, dated as of January 1, 1992 (incorporated by reference to Exhibit 10.36 to the Company's Form 10-K for the fiscal year ended December 31, 1991). 10.20 - Cooperative Research and Development Agreement between the Company and the National Institutes of Health, dated as of January 21, 1992 (incorporated by reference to Exhibit 10.37 to the Company's Form 10-K for the fiscal year ended December 31, 1991). 10.21 - Letter Agreement between the Company and Robert H. Roth dated April 14, 1994 (incorporated by reference to Exhibit 10.26 to the Company's Form 10-K for the fiscal year ended December 31, 1994). 10.22 - Letter Agreement between the Company and Barry M. Bloom, dated January 12, 1994 (incorporated by reference to Exhibit 10.25 to the Company's Form 10-K for the fiscal year ended December 31, 1993). 10.23 - Collaborative Research Agreement between the Company and Pfizer Inc, dated as of July 1, 1994 (incorporated by reference of Exhibit 10.1 to the Company's Form 10-Q for the quarterly period ended June 30, 1994). 10.24 - Stock Purchase Agreement between the Company and Pfizer dated as of July 1, 1994 (incorporated by reference to Exhibit 10.2 to the Company's Form 10-Q for the quarterly period ended June 30, 1994). 10.25 - Registration Rights and Standstill Agreement Among Neurogen Corporation and the Persons and Entities listed on Schedule I thereto, dated as of July 11, 1994 (incorporated by reference to Exhibit 10.29 to the Company's Form 10-Q for the quarterly period ended September 30, 1994). 10.26 - Collaborative Research Agreement between the Company and Schering-Plough Corporation (incorporated by reference to Exhibit 10.1 to the Company's Form 8-K dated July 28, 1995. 10.27 Lease Agreement between the Company and Commercial Building Associates dated as of July 26, 1995. 11.1 Computation of Income (Loss) per Common Share. 27.1 Financial Data Schedule.