EXHIBIT 21

Applied Bioscience International Inc. and Subsidiaries

SUBSIDIARIES

The subsidiaries of Applied Bioscience International Inc., as of March 15,
1996, are as follows:

Jurisdiction of Incorporation or
Name of Subsidiary Organized in
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Pharmaco International Inc. Texas
Pharmaco International Holdings Inc. Delaware
Pharmaco LSR GmbH Germany
Pharmaco LSR S.A. France
Notsallow 33 Ltd. United Kingdom
Pharmaco Investments, Inc. Delaware
Pharmaco UK Ltd. United Kingdom
APBI Environmental Sciences Group, Inc. Virginia
ENVIRON International Investments, Inc. Delaware
Paragon Global Services, S.A. Luxembourg
APBI Investor Relations, Inc. New Jersey
APBI Finance Corporation Delaware
Leicester Clinical Research Centre Ltd. United Kingdom
PLSR Scandinavia AB Sweden
Pharmaco LSR S.L. Spain
PLSR Beteiligungsverwaltungs GmbH Germany
PLSR Sp. zo.o. Poland
PLSR Praha, s.r.o. Czech Republic
Clinix International Inc. Delaware
Cambridge Applied Nutrition Toxicology and Biosciences Limited United Kingdom
Clinical Technology Centre (International) Limited United Kingdom
Clinical Science Research International Limited United Kingdom

Pharmaco International Inc.; Pharmaco UK Ltd.; APBI Environmental Sciences
Group, Inc.; APBI Investor Relations, Inc., APBI Finance Corporation, Leicester
Clinical Research Centre, Ltd., and Clinix International Inc., are wholly owned
subsidiaries of Applied Bioscience International Inc.

Pharmaco International Holdings Inc. and Pharmaco Investments, Inc. are wholly
owned subsidiaries of Pharmaco International Inc.

Pharmaco LSR S.A., Notsallow 33 Ltd., PLSR Scandinavia AB, Pharmaco LSR S.L.,
and PLSR Beteiligungsverwaltungs GmbH are wholly owned subsidiaries of
Pharmaco International Holdings Inc.

Pharmaco LSR GmbH is owned 74% by Pharmaco International Holdings Inc., and 26%
by PLSR Beteiligungsverwaltungs GmbH.

PLSR Sp. zo.o. and PLSR Praha, s.r.o. are wholly owned subsidiaries of PLSR
Beteiligungsverwaltungs GmbH.

ENVIRON International Investments, Inc. and Paragon Global Services, S.A. are
wholly owned subsidiaries of APBI Environmental Sciences Group, Inc.

Cambridge Applied Nutrition Toxicology and Bioscience Limited, Clinical
Technology Centre (International) Limited and Clinical Science Research
International Limited are wholly owned subsidiaries of Pharmaco U.K. Ltd.

APBI Environmental Sciences Group, Inc., does business under the trade name
ENVIRON.

Clinix International Inc., does business under the trade name the Chicago
Center for Clinical Research.