1 EXHIBIT No. 11 APPLIED BIOSCIENCE INTERNATIONAL INC. AND SUBSIDIARIES COMPUTATION OF EARNINGS PER SHARE (in thousands, except per share amounts) Three Months Ended, March 31 1996 1995 ----------- ----------- PRIMARY EARNINGS PER SHARE: Net income $ 1,227 $ 436 =========== =========== Weighted average number of shares of common outstanding during the period 29,271 28,173 Common stock equivalents assuming exercise of stock options (a) 414 257 ----------- ----------- Weighted average common and common equivalent shares outstanding 29,685 28,430 =========== =========== Primary earnings per share $0.04 $0.02 =========== =========== FULLY DILUTED EARNINGS PER SHARE: Net income $ 1,227 $ 436 =========== =========== Weighted average number of shares of common outstanding during the period 29,271 28,173 Common stock equivalents assuming exercise of stock options (a) 574 261 ----------- ----------- Weighted average common and common equivalent shares outstanding 29,845 28,434 =========== =========== Fully diluted earnings per share $0.04 $0.02 =========== =========== (a) In the calculation of common stock equivalents, stock options are assumed to be exercised at the beginning of the period. The proceeds from the options exercised are assumed to be used to purchase common stock at (i) the average market price during the period for primary earnings per share and (ii) the higher of the average or last market price during the period for fully diluted earnings per share. 12