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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K

- --------------------------------------------------------------------------------


                                 CURRENT REPORT
     PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934


      Date of Report (Date of Earliest Event Reported): December 28, 2000



                                 AMEDISYS, INC.
               --------------------------------------------------
               (Exact Name of Registrant as Specified in Charter)


                                    Delaware
                         -------------------------------
                         (State or Other Jurisdiction of
                         Incorporation or Organization)



                                                         
         0-24260                                                        11-3131700
- ------------------------                                    ------------------------------------
(Commission File Number)                                    (I.R.S. Employer Identification No.)



                   11100 Mead Road, Suite 300, Baton Rouge, LA
                  ---------------------------------------------
                  70816 (Address of principal executive offices
                               including zip code)


                                 (225) 292-2031
              ----------------------------------------------------
              (Registrant's telephone number, including area code)

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 ITEM 5.          OTHER EVENTS

                           On December 28, 2000, the Company entered into a loan
                  agreement with NPF Capital, Inc. ("NPF") for a principal sum
                  of up to $11,725,000. At execution, NPF paid $9,000,000
                  directly to HCA, The Healthcare Company f/k/a Columbia HCA
                  Healthcare Corp ("HCA") for the benefit of the Company. The
                  Company also financed $725,000 of debt issue costs under this
                  agreement, with the remaining unfunded portion of $2,000,000
                  available for future acquisitions. Simultaneously, Amedisys
                  entered into a Termination Agreement with HCA relating to the
                  note payable ("HCA Note") which resulted from the acquisition
                  of home health agencies from HCA during the latter part of
                  1998. The HCA Note, which carried a balance (including accrued
                  interest) of $16.6 million at September 30, 2000, was
                  terminated effective October 1, 2000 for a cash payment of
                  $9,000,000 and the execution of a warrant agreement that
                  allows HCA to purchase up to 200,000 shares of Amedisys'
                  Common Stock, subject to certain conditions. As of result of
                  these transactions, the Company has recorded a pre-tax
                  extraordinary gain of $6.5 million in the fourth quarter of
                  2000.

                           The loan agreement with NPF Capital, Inc. ("NPF
                  Note"), an affiliate of National Century Financial
                  Enterprises, Inc., is for a principal sum not to exceed
                  $11,725,000 at an annual interest rate of 13.95%, adjustable
                  in accordance with the loan agreement. At loan execution, the
                  Company borrowed an amount ("Initial Loan Amount") equal to
                  $9,000,000 which was paid directly to HCA. The Initial Loan
                  Amount is payable over a three year term with interest only
                  payments for the first six months and monthly payments of
                  principal and interest for the remainder of the term. The
                  Company has available an amount not to exceed $2,000,000
                  ("Supplemental Loan Amount") for the acquisition of
                  businesses, companies and/or their assets. Any Supplemental
                  Loan Amounts received will be payable over a three year term
                  commencing upon receipt of the Supplemental Loan Amount with
                  thirty-six monthly principal and interest payments. The fees
                  charged by NPF relating to the NPF Note totaled $725,000 and
                  are payable in accordance with the payment terms of the
                  Initial Loan Amount. The security for this note consists of
                  all credits, deposits, account, securities or moneys, and all
                  other property rights belonging to or in which the Company has
                  any interest, now or hereafter, as well as every other
                  liability now or hereafter existing of the Company, absolute
                  or contingent, due or to become due. In addition, the net cash
                  proceeds received from the divestiture of the Company's
                  remaining surgery center are payable to NPF.

                           In connection with the execution of the NPF Note
                  discussed above, the Company, on December 29, 2000, entered
                  into a Termination Agreement with HCA effective October 1,
                  2000. The Termination Agreement related to that certain Credit
                  Agreement dated November 16, 1998 and that certain promissory
                  note dated December 1, 1998 as modified by that certain Loan
                  Modification Agreement dated September 30, 1999. In
                  accordance with the conditions of the Termination Agreement,
                  the Company paid $9,000,000 in cash and entered into a
                  Master Warrant Agreement, dated December 29, 2000, whereas
                  HCA shall be issued warrants to purchase up to 200,000 shares
                  of Company Common Stock, subject to the terms and conditions
                  of the Warrant Agreement, in full satisfaction of all amounts
                  due to HCA, including interest accrued but not paid.

                           In the Master Warrant Agreement, HCA was granted a
                  Warrant Certificate to purchase 50,000 shares of Company
                  Common Stock ("Initial Grant") at an exercise price of $5.00
                  expiring on December 28, 2005. Subsequent grants are
                  conditional and evaluated at the end of Year 2001, Year 2002,
                  and Year 2003 in accordance with the following:

                  Year 2001 Grant.

                           a)       If, on December 28, 2001, the Market Price,
                                    (as defined in the Warrant Certificate) of
                                    Amedisys common stock is greater than or
                                    equal to $10.00, then HCA shall not be
                                    entitled to, and Amedisys shall not be
                                    obligated for, any year 2001 Warrant grant.

                           b)       If, on December 28, 2001, the Market Price
                                    of Amedisys common stock is less than or
                                    equal to $5.00, then HCA shall be entitled
                                    to, and Amedisys shall grant to HCA, on
                                    December 29, 2001, a Warrant Certificate
                                    evidencing the right to purchase, at any
                                    time from December 29, 2001, until 5:00 p.m.
                                    CST, on December 28, 2006 (the "2001 Warrant
                                    Exercise Term"), up to 50,000 fully-paid and
                                    non-assessable Shares at an initial exercise
                                    price of $5.00.


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                           c)       If, on December 28, 2001, the Market Price
                                    of Amedisys common stock is greater than
                                    $5.00 but less than $10.00, then HCA shall
                                    be entitled to, and Amedisys shall grant to
                                    HCA, on December 29, 2001, the right to
                                    purchase, at any time during the 2001
                                    Warrant Exercise Term, up to the Pro Rata
                                    Share Amount, as defined below, of
                                    fully-paid and non-assessable Shares at an
                                    initial exercise price equal to the Market
                                    Price.

                                    The term "Pro Rata Share Amount," as used in
                                    this subsection, shall refer to that number
                                    calculated by subtracting the Market Price
                                    from $10.00, then dividing the total by
                                    $5.00, then multiplying the resulting
                                    quotient by 50,000. For example, if the
                                    Market Price on December 28, 2001, is $6.00,
                                    the Pro Rata Share Amount would be 40,000 as
                                    follows:

                                    [($10.00 - $6.00) / $5.00] x 50,000 = 40,000

                  Year 2002 Grant.

                           a)       If, on December 28, 2002, the Market Price
                                    of Amedisys common stock is greater than or
                                    equal to $15.00, then HCA shall not be
                                    entitled to, and Amedisys shall not be
                                    obligated for, any year 2002 Warrant grant.

                           b)       If, on December 28, 2002, the Market Price
                                    of Amedisys common stock is less than or
                                    equal to $10.00, then HCA shall be entitled
                                    to, and Amedisys shall grant to HCA, on
                                    December 29, 2002, a Warrant Certificate
                                    evidencing the right to purchase, at any
                                    time from December 29, 2002, until 5:00 p.m.
                                    CST, on December 28, 2007 (the "2002 Warrant
                                    Exercise Term"), up to 50,000 fully-paid and
                                    non-assessable Shares at an initial exercise
                                    price equal to the greater of (i) $5.00; and
                                    (ii) the Market Price.


                           c)       If, on December 28, 2002, the Market Price
                                    of Amedisys common stock is greater than
                                    $10.00 but less than $15.00, then HCA shall
                                    be entitled to, and Amedisys shall grant to
                                    HCA, on December 29, 2002, a Warrant
                                    Certificate evidencing the right to
                                    purchase, at any time during the 2002
                                    Warrant Exercise Term, up to the Pro Rata
                                    Share Amount, as defined below, of
                                    fully-paid and non-assessable Shares at an
                                    initial exercise price equal to the Market
                                    Price.

                                    The term "Pro Rata Share Amount," as used in
                                    this subsection, shall refer to that number
                                    calculated by subtracting the Market Price
                                    from $15.00, then dividing the total by
                                    $5.00, then multiplying the resulting
                                    quotient by 50,000. For example, if the
                                    Market Price on December 28, 2002, is
                                    $13.00, the Pro Rata Share Amount would be
                                    20,000 as follows:

                                    [($15.00 - $13.00) / $5.00] x 50,000 =
                                    20,000

                  Year 2003 Grant.

                           a)       If, on December 28, 2003, the Market Price
                                    of Amedisys common stock is greater than or
                                    equal to $20.00, then HCA shall not be
                                    entitled to, and Amedisys shall not be
                                    obligated for, any year 2003 Warrant grant.

                           b)       If, on December 28, 2003, the Market Price
                                    of Amedisys common stock is less than or
                                    equal to $15.00, then HCA shall be entitled
                                    to, and Amedisys shall grant to HCA, on
                                    December 29, 2003, a Warrant Certificate
                                    evidencing the right to purchase, at any
                                    time from December 29, 2003, until 5:00 p.m.
                                    CST, on December 28, 2008 (the "2003 Warrant
                                    Exercise Term"), up to 50,000 fully-paid and
                                    non-assessable Shares at an initial exercise
                                    price equal to the greater of (i) $5.00; and
                                    (ii) the Market Price.


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                           c)       If, on December 28, 2003, the Market Price
                                    of Amedisys common stock is greater than
                                    $15.00 but less than $20.00, then HCA shall
                                    be entitled to, and Amedisys shall grant to
                                    HCA, on December 29, 2003, a Warrant
                                    Certificate evidencing the right to
                                    purchase, at any time during the 2003
                                    Warrant Exercise Term, up to the Pro Rata
                                    Share Amount, as defined below, of
                                    fully-paid and non-assessable Shares at an
                                    initial exercise price equal to the Market
                                    Price.

                                    The term "Pro Rata Share Amount," as used in
                                    this subsection, shall refer to that number
                                    calculated by subtracting the Market Price
                                    from $20.00, then dividing the total by
                                    $5.00, then multiplying the resulting
                                    quotient by 50,000. For example, if the
                                    Market Price on December 28, 2003, is
                                    $19.00, the Pro Rata Share Amount would be
                                    10,000 as follows:

                                    [($20.00 - $19.00) / $5.00] x 50,000 =
                                    10,000


ITEM 7.           FINANCIAL STATEMENTS AND EXHIBITS

                  (a)      Financial Statements of Business Acquired.

                           Not applicable.

                  (b)      Pro Forma Financial Information.

                           Not applicable.



                  (c)      Exhibit
                              No.                                                                                             Page
                           -------                                                                                            ----
                                                                                                                          
                            4.1 (i) Master Warrant Agreement by and between Amedisys, Inc. and HCA -
                                    The Healthcare Company, including Warrant Certificate and Registration Rights Agreement....A-1

                           10.1 (i) Termination of Credit Agreement by and between Amedisys, Inc.
                                    and HCA - The Healthcare Company...........................................................A-2

                           10.2 (i) Cognovit Promissory Note between Amedisys, Inc. and Affiliates and NPF  Capital, Inc. .....A-3

                           99.1 (i) Press Release dated January 16, 2001 announcing the pre-payment
                                    of the HCA - The Healthcare Company note payable...........................................A-4

                           (i) Filed herewith.



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                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

AMEDISYS, INC.

By:   /s/ John M. Joffrion
     -------------------------------------
John M. Joffrion
Senior Vice President of Finance
Principal Accounting and Financial Officer

DATE: January 16, 2001

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                               INDEX TO EXHIBITS



Exhibit
   No.                                                                     Page
- -------                                                                    ----
                                                                         
 4.1 (i) Master Warrant Agreement by and between Amedisys, Inc. and
         HCA - The Healthcare Company, including Warrant Certificate
         and Registration Rights Agreement..................................A-1

10.1 (i) Termination of Credit Agreement by and between Amedisys, Inc.
         and HCA - The Healthcare Company...................................A-2

10.2 (i) Cognovit Promissory Note between Amedisys, Inc. and Affiliates
         and NPF  Capital, Inc. ............................................A-3

99.1 (i) Press Release dated January 16, 2001 announcing the pre-payment
         of the HCA - The Healthcare Company note payable...................A-4

(i) Filed herewith.