EXHIBIT 99.4 UNAUDITED PRO FORMA FINANCIAL INFORMATION The following unaudited pro forma condensed combined financial statements are presented for illustrative purposes only and are not necessarily indicative of the combined financial position or results of operations for future periods or the financial position or results of operations that actually would have been realized had American Medical Systems Holdings, Inc. and Cryogen, Inc. been a combined company during the specified periods. The unaudited pro forma condensed combined financial statements, including the related notes, are qualified in their entirety by reference to, and should be read in conjunction with, the historical financial statements and related notes of American Medical Systems Holdings, Inc., included in its Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on March 29, 2002 and October 28, 2002, respectively, and the historical audited financial statements and related notes of Cryogen, Inc., included elsewhere in this Form 8-K/A. The following unaudited pro forma condensed combined financial statements are accounted for in accordance with Statement of Financial Accounting Standards No. 141, Business Combinations. The pro forma adjustments are based upon preliminary estimates and available information. Final purchase accounting adjustments may differ from the pro forma adjustments presented. The pro forma condensed combined financial statements are based on the respective historical financial statements of American Medical Systems Holdings, Inc. and Cryogen, Inc. and assumes the acquisition took place on January 1, 2001, for the statements of operations, and September 29, 2002, for the balance sheet. The pro forma adjustments are based on the estimates and assumptions set forth in the notes to such statements. AMERICAN MEDICAL SYSTEMS HOLDINGS, INC. UNAUDITED PRO FORMA CONDENSED COMBINED BALANCE SHEET AS OF SEPTEMBER 29, 2002 (THOUSANDS) <Table> <Caption> AMERICAN MEDICAL PRO FORMA SYSTEMS CRYOGEN ADJUSTMENTS COMBINED ------------ ------------ ------------ ------------ ASSETS Current assets: Cash and cash equivalents $ 71,801 $ 1,803 $ (40,000)(a) $ 32,411 (1,193)(c) Accounts receivable, net 25,244 693 -- 25,937 Inventories 13,533 2,382 -- 15,915 Deferred taxes 6,912 -- -- 6,912 Other current assets 2,431 164 -- 2,595 ------------ ------------ ------------ ------------ Total current assets 119,921 5,042 (41,193) 83,770 Property, plant and equipment, net 21,926 1,410 23,336 Goodwill, net 82,365 -- 35,698(a) 118,063 Intangibles, net 14,096 411 14,507 Deferred income taxes 2,230 -- -- 2,230 Investments in technology and other assets 4,756 56 -- 4,812 ------------ ------------ ------------ ------------ Total assets $ 245,294 $ 6,919 $ (5,495) $ 246,718 ============ ============ ============ ============ LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Accounts payable $ 2,298 $ 471 -- $ 2,769 Accrued liabilities 21,200 1,687 (7,085)(b) 15,802 Bank loans -- 360 -- 360 Current portion of notes payable 5,454 29 -- 5,483 ------------ ------------ ------------ ------------ Total current liabilities 28,952 2,547 (7,085) 24,414 Long-term notes payable 19,909 70 -- 19,979 Other long-term liabilities 1,241 -- -- 1,241 Redeemable convertible preferred stock -- 47,564 (47,564)(a) -- Stockholders' equity: Convertible preferred stock -- 13,501 (13,501)(a) -- Common stock 324 436 (436)(a) 324 Additional paid-in capital 197,622 -- 197,622 Deferred compensation (239) -- (239) Accumulated other comprehensive loss (1,465) -- (1,465) Accumulated deficit (1,050) (57,199) 57,199(a) 4,842 7,085(b) (1,193)(c) ------------ ------------ ------------ ------------ Total stockholders' equity 195,192 (43,262) 49,154 201,084 ------------ ------------ ------------ ------------ Total liabilities and stockholders' equity $ 245,294 $ 6,919 $ (5,495) $ 246,718 ============ ============ ============ ============ </Table> The accompanying notes are an integral part of the consolidated financial statements. AMERICAN MEDICAL SYSTEMS HOLDINGS, INC. UNAUDITED PRO FORMA COMBINED STATEMENT OF OPERATIONS FOR THE YEAR ENDED DECEMBER 29, 2001 (THOUSANDS, EXCEPT PER SHARE DATA) <Table> <Caption> AMERICAN MEDICAL PRO FORMA SYSTEMS CRYOGEN ADJUSTMENTS COMBINED ------------ ------------ ------------ ------------ Net sales $ 117,938 $ 1,950 -- 119,888 Operating expenses: Cost of sales 23,140 3,880 -- 27,020 Marketing and sales 44,931 7,208 -- 52,139 General and administrative 12,156 2,618 -- 14,774 Research and development 11,899 1,814 -- 13,713 Transition and reorganization 1,000 -- -- 1,000 Amortization of intangibles 9,374 -- -- 9,374 ------------ ------------ ------------ ------------ Total operating costs 102,500 15,520 -- 118,020 Operating income (loss) 15,438 (13,570) -- 1,868 Royalty income 2,926 -- -- 2,926 Other income (expense) (3,030) -- -- (3,030) Interest expense, net (2,932) (60) (1,100)(c) 4,092 ------------ ------------ ------------ ------------ Income (loss) before income taxes 12,402 (13,630) (1,100) (2,328) Income tax expense (5,872) -- 5,179(b) (275) 418(c) ------------ ------------ ------------ ------------ Net income (loss) $ 6,530 $ (13,630) $ 4,497 $ (2,603) ============ ============ ============ ============ Earnings per share: Basic $ 0.22 $ (0.08) Diluted $ 0.20 (0.08) Weighted average common shares: Basic 29,792 29,792 Diluted 32,068 29,792 </Table> The accompanying notes are an integral part of the consolidated financial statements AMERICAN MEDICAL SYSTEMS HOLDINGS, INC. UNAUDITED PRO FORMA COMBINED STATEMENT OF OPERATIONS FOR THE NINE-MONTHS ENDED SEPTEMBER 29, 2002 (THOUSANDS, EXCEPT PER SHARE DATA) <Table> <Caption> AMERICAN MEDICAL PRO FORMA SYSTEMS CRYOGEN ADJUSTMENTS COMBINED ------------ ------------ ------------ ------------ Net sales $ 103,816 $ 2,048 -- $ 105,864 Operating expenses: Cost of sales 20,485 442 -- 20,927 Marketing and sales 37,195 3,498 -- 40,693 General and administrative 9,816 2,209 -- 12,025 Research and development 8,727 958 -- 9,685 Transition and reorganization -- -- -- -- Amortization of intangibles 2,817 -- -- 2,817 ------------ ------------ ------------ ------------ Total operating expenses 79,040 7,107 -- 86,147 Operating income (loss) 24,776 (5,059) -- 19,717 Royalty income 2,279 -- -- 2,279 Other income (expense) 964 -- -- 964 Interest expense, net (852) 44 (825)(c) (1,633) ------------ ------------ ------------ ------------ Income (loss)before income taxes 27,167 (5,015) (825) 21,327 Income tax benefit (expense) (10,612) -- 1,906(b) (8,392) 314(c) ------------ ------------ ------------ ------------ Net income (loss) $ 16,555 $ (5,015) $ 1,395 $ 12,935 ============ ============ ============ ============ Earnings per share: Basic $ 0.51 $ 0.40 Diluted $ 0.48 $ 0.38 Weighted average common shares: Basic 32,155 32,155 Diluted 34,230 34,230 </Table> The accompanying notes are an integral part of the consolidated financial statements. AMERICAN MEDICAL SYSTEMS HOLDINGS, INC. NOTES TO UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS 1. ALLOCATION OF PURCHASE PRICE For this presentation, the Company allocated the December 30, 2002 estimated purchase price of Cryogen, Inc. as follows: <Table> <Caption> (amounts in thousands) Amount - ---------------------- ------------ Goodwill $ 35,698 Assets acquired, net of liabilities assumed 4,302 ------------ $ 40,000 ============ </Table> The purchase price allocation to the assets and liabilities assumed was based on a preliminary estimate to determine their respective values. The Company believes that the preliminary allocations set forth herein are reasonable, but are subject to revision upon completion of a planned independent valuation study. 2. KEY TO PRO FORMA ADJUSTMENTS The unaudited pro forma condensed combined balance sheet and statements of operations include the adjustments necessary to give effect to the purchase and to reflect the allocation of the purchase price to the fair value of the assets acquired as noted above, including the elimination of Cryogen, Inc.'s equity accounts. Summarized below are the pro forma adjustments necessary to reflect the acquisition of Cryogen, Inc. based upon the purchase method of accounting in accordance with SFAS 141, Business Combinations. (a) Record the consideration paid for Cryogen, elimination of Cryogen equity accounts, and reflect the excess of the purchase price over the assets acquired. (b) Record the tax benefit from the net losses recorded by CryoGen. (c) To adjust net interest expense due to lower investment income from lower cash balances.