. . . Exhibit 99.2 CONNETICS CORPORATION INDEX TO UNAUDITED PRO FORMA CONSOLIDATED FINANCIAL STATEMENTS Page ---- Unaudited Pro Forma Consolidated Financial Statements................................. 2 Unaudited Pro Forma Consolidated Balance Sheet as of December 31, 2003................................................................ 3 Notes to Unaudited Pro Forma Consolidated Balance Sheet............................... 4 Unaudited Pro Forma Consolidated Statement of Operations for the Year Ended December 31, 2003............................................. 5 Notes to Unaudited Pro Forma Consolidated Statement of Operations..................... 6 1 CONNETICS CORPORATION UNAUDITED PRO FORMA CONSOLIDATED FINANCIAL STATEMENTS The following Unaudited Pro Forma Consolidated Financial Statements have been prepared to give effect to the recent acquisition by Connetics Corporation ("Connetics") of the exclusive U.S. rights to Soriatane(R)-brand (acitretin) from Hoffmann-La Roche Inc. (the "Soriatane Product Line") on March 4, 2004. The Unaudited Pro Forma Consolidated Balance Sheet as of December 31, 2003, gives effect to the acquisition as if it had occurred on December 31, 2003. The Unaudited Pro Forma Consolidated Statement of Operations for the year ended December 31, 2003 gives effect to the acquisition as if it had occurred on January 1, 2003. The pro forma adjustments are based upon available information and certain assumptions that Connetics believes are reasonable under the circumstances. Pro forma adjustments are applied to the historical financial statements of Connetics and the acquisition. The transaction was accounted for as an acquisition of intangible assets. The Unaudited Pro Forma Consolidated Financial Statements should be read in conjunction with (1) Connetics' historical Consolidated Financial Statements and related Notes thereto, Management's Discussion and Analysis of Financial Condition and Results of Operations included in Connetics' Annual report on Form 10-K for the year ended December 31, 2003, and (2) the financial statements of the Soriatane Product Line included elsewhere in this Current Report on Form 8-K/A dated March 4, 2004. The Unaudited Pro Forma Consolidated Financial Statements and related notes are provided for information purposes only and do not purport to be indicative of the results which would have actually been obtained had the acquisition been completed on the date indicated or which may be expected to occur in the future. 2 CONNETICS CORPORATION UNAUDITED PRO FORMA CONSOLIDATED BALANCE SHEET AS OF DECEMBER 31, 2003 (In thousands) SORIATANE PRO FORMA CONNETICS PRODUCT LINE ADJUSTMENTS PRO FORMA ASSETS Current assets: Cash, cash equivalents and marketable securities $ 114,662 $ 56,910 (1) $ 48,572 (123,000)(2) Restricted cash - current 304 304 Accounts receivable, net 2,594 2,594 Prepaid expenses and other current assets 4,814 1,460 6,274 - ----------------------------------------------------------------------------------------------------------------- Total current assets 122,374 1,460 (66,090) 57,744 Property and equipment, net 5,628 5,628 Debt issuance costs, deposits and other assets 5,418 5,418 Goodwill, net 6,271 6,271 Other intangible assets, net 6,206 127,241 (3) 133,447 - ----------------------------------------------------------------------------------------------------------------- Total assets $ 145,897 $ 1,460 $ 61,151 $ 208,508 ================================================================================================================= LIABILITIES AND SHAREHOLDERS' EQUITY Current liabilities: Accounts payable $ 3,884 $ 3,884 Accrued payroll and related expenses 3,792 3,792 Accrued clinical trial costs 857 857 Current portion of deferred revenue 19 19 Other accrued liabilities 1,575 3,741 1,960 (4) 7,276 - ----------------------------------------------------------------------------------------------------------------- Total current liabilities 10,127 3,741 1,960 15,828 Convertible senior notes 90,000 90,000 Other non-current liabilities 16 16 Commitments and contingencies STOCKHOLDERS' EQUITY: Preferred stock, $0.001 par value: 5,000,000 shares authorized; none issued or outstanding -- -- Common stock, $0.001 par value; 50,000,000 shares authorized; shares issued and outstanding: 31,885,404 in 2003 and 31,180,436 in 2002 32 32 Additional paid-in capital 174,080 56,910 (1) 230,990 Net assumed liabilities of acquired product line -- (2,281) 2,281 (3) -- Deferred stock compensation (31) (31) Accumulated deficit (130,188) (130,188) Accumulated other comprehensive income 1,861 1,861 - ----------------------------------------------------------------------------------------------------------------- Total stockholders' equity 45,754 (2,281) 59,191 102,664 - ----------------------------------------------------------------------------------------------------------------- Total liabilities and stockholders' equity $ 145,897 $ 1,460 $ 61,151 $ 208,508 ================================================================================================================= See Notes to Unaudited Pro Forma Consolidated Balance Sheet 3 NOTES TO UNAUDITED PRO FORMA CONSOLIDATED BALANCE SHEET (1) Reflects the net proceeds from the issuance of 3,000,000 shares of common stock in a private placement in February 2004. These net proceeds from this private placement were used to help finance the acquisition of the Soriatane Product Line. (2) Reflects the payment of $123.0 million to Hoffmann-La Roche Inc. upon closing of the Soriatane Product Line acquisition. (3) Reflects the acquisition of the Soriatane Product Line from Hoffmann-La Roche Inc. for a purchase price of $123.0 million plus estimated acquisition costs of $500,000 and assumed liabilities of approximately $3.7 million. (4) Reflects an accrued liability of approximately $1.5 million for the purchase of Soriatane inventory plus estimated acquisition costs of $500,000. 4 CONNETICS CORPORATION UNAUDITED PRO FORMA CONSOLIDATED STATEMENT OF OPERATIONS FOR THE YEAR ENDED DECEMBER 31, 2003 (In thousands, except per share data) SORIATANE PRO FORMA CONNETICS PRODUCT LINE ADJUSTMENTS PRO FORMA - --------------------------------------------------------------------------------------------------------------------------------- TOTAL NET REVENUES $ 75,331 $ 41,187 $116,518 OPERATING COSTS AND EXPENSES: Cost of product revenues 5,129 1,915 7,044 Research and development 30,109 30,109 Selling, general and administrative 42,600 15,301 (1,364)(1) 56,537 Amortization of acquired product rights 12,724 (2) 12,724 - ------------------------------------------------------------------------------------------------------------------------------ Total operating costs and expenses 77,838 17,216 11,360 106,414 - ------------------------------------------------------------------------------------------------------------------------------ INCOME (LOSS) FROM OPERATIONS (2,507) 23,971 (11,360) 10,104 INTEREST AND OTHER INCOME (EXPENSE): Interest income 972 972 Interest expense (1,632) (1,632) Other income (expense), net 234 234 - ------------------------------------------------------------------------------------------------------------------------------ Income (loss) before income taxes (2,933) 23,971 (11,360) 9,678 Income tax provision 1,167 5,044 (3) 6,211 - ------------------------------------------------------------------------------------------------------------------------------ Net income (loss) $ (4,100) $ 23,971 $(16,404) $ 3,467 ============================================================================================================================== BASIC INCOME (LOSS) PER COMMON SHARE -- $ (0.13) $ 0.10 ============================================================================================================================== DILUTED INCOME (LOSS) PER COMMON SHARE -- $ (0.13) $ 0.10 - ------------------------------------------------------------------------------------------------------------------------------ ============================================================================================================================== Shares used to compute basic net income (loss) per share 31,559 3,000(4) 34,559 Shares used to compute diluted net income (loss) per share 31,559 3,000 36,377 (5) ============================================================================================================================== See Notes to Unaudited Pro Forma Consolidated Statement of Operations 5 NOTES TO UNAUDITED PRO FORMA CONSOLIDATED STATEMENT OF OPERATIONS (1) To remove non-recurring restructuring related charges incurred by Hoffmann-La Roche Inc. (2) Represents amortization of intangible assets acquired over the estimated useful lives of 10 years. (3) Assumes a combined federal and state statutory rate of 40% for 2003 applied to the unaudited incremental pro forma income before taxes. Connetics did not consider the use of any available net operating loss carry forwards. (4) Reflects shares issued in a private placement of common stock in February 2004 to help finance the acquisition of the Soriatane Product Line. (5) Includes 49,321 weighted average warrants and 1,769,242 weighted average stock options outstanding during the period. 6