EXHIBIT 32.1

                             APPLIED MATERIALS, INC.
                  SARBANES-OXLEY ACT SECTION 906 CERTIFICATION

In connection with this quarterly report on Form 10-Q of Applied Materials, Inc.
for the period ended January 30, 2005, I, Michael R. Splinter, President and
Chief Executive Officer of Applied Materials, Inc., hereby certify pursuant to
18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley
Act of 2002, that:

      1.    this Form 10-Q for the period ended January 30, 2005 fully complies
            with the requirements of section 13(a) or 15(d) of the Securities
            Exchange Act of 1934; and

      2.    the information contained in this Form 10-Q for the period ended
            January 30, 2005 fairly presents, in all material respects, the
            financial condition and results of operations of Applied Materials,
            Inc. for the periods presented therein.

Date: March 1, 2005

                                       By: /S/ MICHAEL R. SPLINTER
                                           -------------------------------
                                           Michael R. Splinter
                                           President and Chief Executive Officer