[Janus letterhead] September 27, 2005 EDGAR Operations Branch Securities and Exchange Commission Division of Investment Management 450 Fifth Street, N.W. Washington, D.C. 20549 Re: JANUS INVESTMENT FUND (the "Registrant") 1933 Act File No. 2-34393 1940 Act File No. 811-1879 Dear Sir or Madam: On behalf of the Registrant, enclosed please find soliciting material pursuant to Rule 14a-12 relating to the preliminary proxy statement filed with the Securities and Exchange Commission on September 22, 2005. No fee is required in connection with this filing pursuant to Rule 14a-6 under the Securities Exchange Act of 1934. Please call me at (303) 336-7823 with any questions or comments. Very truly yours, /s/Richard C. Noyes Richard C. Noyes Associate Counsel Enc. cc: Cindy Antonson Donna Brungardt Stephanie Grauerholz-Lofton, Esq. Larry Greene, Esq. Kelley Abbott Howes, Esq.