[Janus letterhead] August 27, 2008 EDGAR Operations Branch Securities and Exchange Commission Division of Investment Management 100 F Street, NE Washington, DC 20549-0505 Re: JANUS INVESTMENT FUND (the "Registrant") 1933 Act File No. 2-34393 1940 Act File No. 811-1879 Dear Sir or Madam: On behalf of the Registrant, enclosed please find definitive additional materials filed on Schedule 14A relating to the definitive proxy statement filed with the Securities and Exchange Commission on August 27, 2008. No fee is required in connection with this filing pursuant to Rule 14a-6 under the Securities Exchange Act of 1934. If you have any questions regarding this filing, please call me at (303) 336-4045. Sincerely, /s/ Robin Nesbitt Robin Nesbitt Associate Counsel Enclosure cc: Stephanie Grauerholz-Lofton, Esq. Larry Greene, Esq. Cindy A. Antonson Donna Brungardt