1 SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED: SEPTEMBER 30, 2000 OR ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM _____ TO _____ COMMISSION FILE NUMBER: 0-21696 ARIAD PHARMACEUTICALS, INC. (Exact name of Registrant as specified in its charter) DELAWARE 22-3106987 (State or other jurisdiction of (I.R.S. Employer Identification No.) incorporation or organization) 26 LANDSDOWNE STREET, CAMBRIDGE, MASSACHUSETTS 02139 (Address of principal executive offices)(Zip Code) REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (617) 494-0400 Former Name, Former Address and Former Fiscal Year, If Changed Since Last Report: Not Applicable Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. YES X NO --- --- The number of shares of the Registrant's common stock outstanding as of November 3, 2000 was 27,108,867. 2 ARIAD PHARMACEUTICALS, INC. TABLE OF CONTENTS PART I. FINANCIAL INFORMATION Page No. - ------------------------------- -------- ITEM 1 UNAUDITED FINANCIAL STATEMENTS: Condensed Consolidated Balance Sheets - September 30, 2000 and December 31, 1999------------------------------------------------1 Condensed Consolidated Statements of Operations for the Three Months and Nine Months Ended September 30, 2000 and 1999-------2 Condensed Consolidated Statements of Cash Flows for the Nine Months Ended September 30, 2000 and 1999------------------------3 Notes to Unaudited Condensed Consolidated Financial Statements-------4 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS----------------------------------7 ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK----------11 PART II. OTHER INFORMATION - --------------------------- ITEM 5. OTHER INFORMATION --------------------------------------------------12 ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K------------------------------------12 3 PART I. FINANCIAL INFORMATION ITEM 1. UNAUDITED FINANCIAL STATEMENTS ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED) ASSETS SEPTEMBER 30, DECEMBER 31, 2000 1999 -------------- --------------- Current assets: Cash and cash equivalents $ 7,599,571 $ 28,319,870 Marketable securities 30,567,252 Inventory and other current assets 1,581,646 1,608,695 -------------- --------------- Total current assets 39,748,469 29,928,565 -------------- --------------- Property and equipment: Leasehold improvements 12,602,318 12,566,650 Equipment and furniture 4,563,478 4,413,453 -------------- --------------- Total 17,165,796 16,980,103 Less accumulated depreciation and amortization 14,571,349 13,645,750 -------------- --------------- Property and equipment, net 2,594,447 3,334,353 -------------- --------------- Intangible and other assets, net 4,903,483 10,973,095 -------------- --------------- Total $ 47,246,399 $ 44,236,013 ============== =============== LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Current portion of long-term debt $ 1,200,000 $ 1,200,000 Accounts payable 1,403,721 2,276,447 Accrued liabilities 1,532,598 3,721,679 -------------- --------------- Total current liabilities 4,136,319 7,198,126 -------------- --------------- Long-term debt 1,000,000 1,900,000 -------------- --------------- Redeemable convertible preferred stock 8,070,415 --------------- Stockholders' equity: Common stock, $.001 par value; authorized, 60,000,000 shares; issued and outstanding, 27,096,523 shares in 2000 and 22,031,888 shares in 1999 27,097 22,032 Additional paid-in capital 127,107,329 101,928,618 Deferred compensation (119,129) Accumulated other comprehensive loss (22,944) Accumulated deficit (84,882,273) (74,883,178) -------------- --------------- Stockholders' equity 42,110,080 27,067,472 -------------- --------------- Total $ 47,246,399 $ 44,236,013 ============== =============== See notes to unaudited condensed consolidated financial statements. 1 4 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED) THREE MONTHS ENDED NINE MONTHS ENDED SEPTEMBER 30, SEPTEMBER 30, -------------------------------- -------------------------------- 2000 1999 2000 1999 ------------- -------------- -------------- -------------- Revenue: Research revenue (principally related parties in 1999) $ 1,050 $ 2,583,349 $ 127,203 $ 9,889,822 Interest income 663,303 18,284 1,422,519 334,580 ------------- -------------- -------------- -------------- Total revenue 664,353 2,601,633 1,549,722 10,224,402 ------------- -------------- -------------- -------------- Operating expenses: Research and development (*) 3,192,621 6,813,407 9,027,514 22,783,873 General and administrative 705,065 949,851 2,348,517 2,564,441 Interest expense 53,737 188,876 172,786 386,122 ------------- -------------- -------------- -------------- Total operating expenses 3,951,423 7,952,134 11,548,817 25,734,436 Equity in net loss of Genomics Center (376,715) (1,142,465) ------------- -------------- -------------- -------------- Loss before cumulative effect of change in accounting principle (3,287,070) (5,727,216) (9,999,095) (16,652,499) ------------- -------------- -------------- -------------- Cumulative effect of change in accounting principle (364,388) ------------- -------------- -------------- -------------- Net loss (3,287,070) (5,727,216) (9,999,095) (17,016,887) Accretion cost attributable to redeemable convertible preferred stock (63,013) (186,986) ------------- -------------- -------------- -------------- Net loss attributable to common stockholders $ (3,287,070) $ (5,790,229) $ (9,999,095) $ (17,203,873) ============= ============== ============== ============== Per common share (basic and diluted): Loss attributable to common stockholders before cumulative effect of change in accounting principle $ (.12) $ (.26) $ (.40) $ (.76) Cumulative effect of change in accounting principle (.02) ------------- -------------- -------------- -------------- Net loss $ (.12) $ (.26) $ (.40) $ (.78) ============= ============== ============== ============== Weighted average number of shares of common stock outstanding 26,943,454 22,019,122 25,405,085 21,995,799 * Includes non-cash stock based compensation 58,115 19,314 130,996 56,974 See notes to unaudited condensed consolidated financial statements. 2 5 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED) NINE MONTHS ENDED SEPTEMBER 30, ------------------------------------- 2000 1999 -------------- -------------- Cash flows from operating activities: Net loss $ (9,999,095) $ (17,016,887) Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization 1,134,450 2,738,780 Stock-based compensation 130,996 56,974 Increase (decrease) from: Inventory and other current assets 27,049 495,094 Due from Genomics Center 128,622 Other assets (397,737) 45,769 Accounts payable (872,726) 702,996 Accrued liabilities (2,163,374) 666,667 Advance from Genomics Center (25,707) 920,988 -------------- -------------- Net cash used in operating activities (12,166,144) (11,260,997) -------------- -------------- Cash flows from investing activities: Purchases of marketable securities (38,665,592) (210,736) Proceeds from sales and maturities of marketable securities 8,156,303 7,762,175 Investment in Genomics Center (6,973,245) Return of investment in Genomics Center 6,032,287 Investment in property and equipment, net (185,693) (461,519) Acquisition of intangible assets (747,408) (550,845) -------------- -------------- Net cash (used in) provided by investing activities (31,442,390) 5,598,117 -------------- -------------- Cash flows from financing activities: Proceeds from issuance of common stock, net of issuance costs 7,539,040 Proceeds from exercise of common stock purchase warrants 11,637,772 Proceeds from issuance of stock pursuant to stock option and purchase plans 4,611,423 151,446 Repayment of borrowings (900,000) (1,391,426) Proceeds from issuance of series B convertible preferred stock 5,747,000 Proceeds from related party long-term debt 1,800,988 Proceeds from sale/leaseback of equipment 308,753 -------------- -------------- Net cash provided by financing activities 22,888,235 6,616,761 -------------- -------------- Net (decrease) increase in cash and equivalents (20,720,299) 953,881 Cash and equivalents, beginning of period 28,319,870 6,501,648 -------------- -------------- Cash and equivalents, end of period $ 7,599,571 $ 7,455,529 ============== ============== See notes to unaudited condensed consolidated financial statements. 3 6 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS 1. MANAGEMENT STATEMENT In the opinion of the Company's management, the accompanying unaudited condensed consolidated financial statements contain all adjustments (consisting of only normal recurring accruals) necessary to present fairly the financial position as of September 30, 2000 and the results of operations for the three month and nine month periods ended September 30, 2000 and 1999. These financial statements should be read in conjunction with the Company's Annual Report on Form 10-K for the year ended December 31, 1999, which includes consolidated financial statements and notes thereto for the years ended December 31, 1999, 1998 and 1997. The results of operations for the three month and nine month periods ended September 30, 2000 are not necessarily indicative of the results to be expected for the full year. 2. MARKETABLE SECURITIES The Company has classified its marketable securities as available for sale and accordingly, carries such securities at aggregate fair value. At December 31, 1999, the Company held no marketable securities. At September 30, 2000, the aggregate fair value was $30,567,252 and amortized cost was $30,590,196. Realized gains and losses on sales of marketable securities were not material during the quarter ended September 30, 2000; the net unrealized loss of $22,944 is included in stockholders' equity at September 30, 2000. 3. INVENTORY Inventories are carried at cost using the first in, first out method and are charged to research and development expense when consumed. Inventory consists of bulk pharmaceutical material to be used for multiple preclinical and clinical drug development programs and amounted to $954,000 at September 30, 2000 and $1,182,000 at December 31, 1999. 4. INTANGIBLE AND OTHER ASSETS Intangible and other assets consist primarily of the cost of purchased patents, patent applications, licenses and deposits. The balance at December 31, 1999 included $6,925,000 of cash subsequently expended on January 14, 2000 to repurchase Series C Redeemable Convertible Preferred Stock (Note 8). 5. LONG-TERM DEBT At September 30, 2000, the Company had outstanding with its principal bank a five-year term loan in the amount of $2,200,000 maturing July 1, 2002. The bank term note is collateralized by all assets of the Company. The Company may, at its option, pledge marketable securities as collateral under the bank term note, and in such event, the interest rate would be adjusted from a rate of prime plus 1.0% to the equivalent of 90-day LIBOR plus 1.25%. 4 7 6. NET LOSS PER SHARE Net loss per share amounts have been computed based on the weighted average number of common shares outstanding during each period. Because of the net loss reported in each period, diluted and basic per share amounts are the same. In 2000 and 1999, options, warrants and the effects of the conversion of convertible preferred stock were not included in the computation of net loss per share because this effect would have been antidilutive. 7. HOECHST-ARIAD GENOMICS CENTER, LLC From November 1995 through December 1999, substantially all of the Company's research revenue and the majority of its research expenses were incurred in collaboration or in partnership with Aventis Pharmaceuticals Inc. (formerly known as Hoechst Marion Roussel, Inc.) ("Aventis") and its affiliates. In November 1995, the Company entered into an agreement with Hoechst Marion Roussel, S.A. to collaborate on the discovery and development of drugs to treat osteoporosis and related bone diseases, one of the Company's signal transduction inhibitor programs. In March 1997, the Company entered into an agreement, which established a 50/50 joint venture, called the Hoechst-ARIAD Genomics Center, LLC (the "Genomics Center"), with Aventis to pursue functional genomics with the goal of identifying genes that encode novel therapeutic proteins and small-molecule drug targets. On December 31, 1999, the Company completed the sale of its 50% interest in the Genomics Center to Aventis and received $40,000,000 in cash, the return of 3,004,436 shares of the Company's series B convertible preferred stock, the forgiveness of $1,857,000 of long-term debt owed to Aventis, drug candidates and related technologies resulting from a November 1995 Osteoporosis collaboration agreement and the right to use certain genomics and bioinformatics technologies developed by the Genomics Center. The Company recorded a net gain on the sale of $46,440,000 for the year ended December 31, 1999. As a result of this sale, the revenue generated from the relationship with Aventis will not recur, and the Company expects to realize a reduction of revenue in fiscal 2000 of $12,340,000, which will be offset by an expected reduction in research and development expenses associated with the Genomics Center of approximately $16,700,000. 8. REDEEMABLE CONVERTIBLE PREFERRED STOCK On January 14, 2000, the Company completed the repurchase of the remaining 3,000 shares of its series C redeemable convertible preferred stock for an aggregate consideration of $6,925,000 plus 1,078,038 shares of common stock. (Note 4). 5 8 9. EQUITY FINANCING FACILITY On June 27, 2000, the Company entered into an Equity Financing Facility (the "Equity Facility") with Acqua Wellington North American Equities Fund, Ltd. ("Acqua Wellington"). Under the terms of the purchase agreement, the Company may from time to time sell up to $75,000,000 of its common stock to Acqua Wellington over an 18 month period expiring in December, 2001. The Company agreed to issue and sell the shares to Acqua Wellington at a per share price equal to the daily volume weighted average price of the Company's common stock on each date during a specified period during which the shares are purchased, less a discount of between 3.5% and 6.0%, or under certain circumstances, less a discount mutually agreed to by the parties. The discount is determined based on the threshold price to be established by the Company for the applicable period. Pursuant to the terms of the Equity Facility, on October 12, 2000, the Company completed the sale of 176,173 shares of common stock to Acqua Wellington at a price of $12.11 per share and received proceeds of $2,133,000. 10. REDEMPTION OF WARRANTS The Company received additional funds aggregating $11.6 million from the exercise of approximately 1.4 million of its publicly traded warrants during the first and second quarters of 2000. Each warrant was exercisable for one share of common stock at an exercise price of $8.40 per share. The warrants had been called for redemption effective April 27, 2000. 11. NEW ACCOUNTING PRONOUNCEMENTS In June 1998, the Financial Accounting Standards Board issued SFAS No. 133, Accounting for Derivative Instruments and Hedging Activities. The new standard requires that all companies record derivatives on the balance sheet as assets or liabilities, measured at fair value. Gains or losses resulting from changes in the values of those derivatives would be accounted for depending on the use of the derivative and whether it qualifies for hedge accounting. Management is currently assessing the impact of SFAS No. 133 on the consolidated financial statements of the Company. The Company will adopt this accounting standard, as amended, on January 1, 2001, as required. In December 1999, the Securities and Exchange Commission ("SEC") issued Staff Accounting Bulletin 101, "Revenue Recognition in Financial Statements" ("SAB 101"), which provides guidance related to revenue recognition based on interpretations and practices followed by the SEC. SAB 101 is effective in the quarter ending December 31, 2000, and requires companies to report any changes in revenue recognition as a cumulative effect of a change in accounting principle at the time of implementation in accordance with Accounting Principles Board Opinion No. 20, "Accounting Changes." The Company is currently assessing the impact of SAB 101 on its financial position and results of operations. 6 9 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS OVERVIEW We are a biopharmaceutical company focused on the discovery, development and commercialization of proprietary platform technologies and therapeutic products based on gene regulation and signal transduction. Our core competencies in functional genomics, protein engineering and structure-based drug design allow us to capitalize on the wealth of genetic information being generated by government, academic and commercial laboratories. We apply this expertise to the development of proprietary technology platforms that allow manipulation of signal transduction, gene transcription, and protein secretion events using small-molecule drugs. We believe that our ability to control the activity of genes and proteins allows us to broadly apply discoveries in genomics to the development of innovative therapeutic products. AVENTIS RELATIONSHIP From November 1995 through December 1999, substantially all of our research revenue and the majority of our research expenses were incurred in collaboration or in partnership with Aventis Pharmaceuticals Inc. (formerly known as Hoechst Marion Roussel, Inc.) ("Aventis") and its affiliates. In November 1995, we entered into an agreement with Hoechst Marion Roussel, S.A. to collaborate on the discovery and development of drugs to treat osteoporosis and related bone diseases (the "1995 Osteoporosis Agreement"), one of our signal transduction inhibitor programs. In March 1997, we entered into an agreement, which established a 50/50 joint venture, called the Hoechst-ARIAD Genomics Center, LLC (the "Genomics Center"), with Aventis to pursue functional genomics with the goal of identifying genes that encode novel therapeutic proteins and small-molecule drug targets. On December 31, 1999, we completed the sale of our 50% interest in the Genomics Center to Aventis and received $40,000,000 in cash, the return of 3,004,436 shares of our series B convertible preferred stock, the forgiveness of $1,857,000 of long-term debt we owed to Aventis, drug candidates and related technologies resulting from the 1995 Osteoporosis Agreement and the right to use certain genomics and bioinformatics technologies developed by the Genomics Center. We recorded a net gain on the sale of $46,440,000 for the year ended December 31, 1999. As a result of this sale, the revenue generated in our relationship with Aventis will not recur, and we expect to realize a reduction of revenue from this relationship in fiscal 2000 of approximately $12,340,000, which will be offset by an expected reduction in research and development expenses associated with the Genomics Center of approximately $16,700,000. GENERAL Since our inception in 1991, we have devoted substantially all of our resources to our research and development programs. We receive no revenue from the sale of pharmaceutical 7 10 products, and substantially all revenue to date has been received in connection with our relationship with Aventis. Except for the gain on the sale of the Genomics Center in December 1999, which resulted in net income for fiscal 1999, we have not been profitable since inception. We expect to continue to incur substantial and increasing operating losses for the foreseeable future, primarily due to the expansion of our research and development programs and manufacturing and clinical development. We expect that losses will fluctuate from quarter to quarter and that these fluctuations may be substantial. As of September 30, 2000, we had an accumulated deficit of $84,882,000. RESULTS OF OPERATIONS THREE MONTHS ENDED SEPTEMBER 30, 2000 COMPARED WITH THE THREE MONTHS ENDED SEPTEMBER 30, 1999 REVENUE We recognized research revenue of $1,000 for the quarter ended September 30, 2000 compared to $2,583,000 for the same period in 1999. Research revenue in 2000 is comprised of transitional research revenue for services provided to Aventis following the December 31, 1999 sale of our interest in the Genomics Center. The decrease in research revenue for the quarter ending September 30, 2000, when compared to the corresponding period in 1999, is due to the termination of research services provided to the Genomics Center and the termination of research revenue associated with the 1995 Osteoporosis Agreement. Research revenue in 1999 was comprised principally of research revenue recognized under the 1995 Osteoporosis Agreement and research services provided to the Genomics Center. Interest income increased by $645,000 to $663,000 for the quarter ended September 30, 2000 compared to $18,000 for the same period in 1999 primarily as a result of higher levels of funds invested during the period. OPERATING EXPENSES Research and development expenses decreased to $3,193,000 for the quarter ended September 30, 2000 compared to $6,813,000 for the same period in 1999 due primarily to the termination of research services provided to the Genomics Center. We expect our research and development expenses to decrease on a comparative basis over the remainder of this year as a result of the termination of research services provided to the Genomics Center. General and administrative expenses decreased to $705,000 for the quarter ended September 30, 2000 compared to $950,000 for the corresponding period in 1999 primarily due to decreased professional and legal services incurred in connection with litigation and a private placement offering that was canceled in 1999. We incurred interest expense of $54,000 for the quarter ended September 30, 2000 compared to $189,000 for the corresponding period in 1999. The decrease resulted from a lower level of long-term debt during the period. 8 11 OPERATING RESULTS We incurred losses of $3,287,000 for the quarter ended September 30, 2000 and $5,727,000 for the corresponding period in 1999, or $.12 and $.26 per share, respectively. We expect that substantial operating losses will continue for several more years but will decrease on a comparative basis over the remainder of this year (exclusive of the gain on sale of the Genomics Center) as a result of the sale of our interest in the Genomics Center. However, operating losses are expected to increase thereafter as our product development activities expand and are expected to fluctuate as a result of differences in the timing and composition of revenue earned and expenses incurred. NINE MONTHS ENDED SEPTEMBER 30, 2000 COMPARED WITH THE NINE MONTHS ENDED SEPTEMBER 30, 1999 REVENUE We recognized research revenue of $127,000 for the nine months ended September 30, 2000 compared to $9,890,000 for the same period in 1999. Research revenue in 2000 is comprised principally of transitional research services provided to Aventis following the December 31, 1999 sale of our interest in the Genomics Center. The decrease in research revenue for the nine months ending September 30, 2000, when compared to the corresponding period in 1999 is due to the termination of research services provided to the Genomics Center and the termination of research revenue associated with the 1995 Osteoporosis Agreement. Research revenue in 1999 was comprised principally of research revenue recognized under the 1995 Osteoporosis Agreement and research services provided to the Genomics Center. As a result of the sale of the Genomics Center and termination of the 1995 Osteoporosis Agreement, we expect to realize a reduction in revenue in fiscal 2000 of approximately $12,340,000 from the termination of our relationship with Aventis. Interest income increased by $1,088,000 to $1,423,000 for the nine months ended September 30, 2000 compared to $335,000 for the same period in 1999 primarily as a result of higher levels of funds invested during the period. OPERATING EXPENSES Research and development expenses decreased to $9,028,000 for the nine months ended September 30, 2000 compared to $22,784,000 for the same period in 1999 due primarily to the termination of research services provided to the Genomics Center as well as a lower level of manufacturing development and other preclinical development costs than had been incurred in the prior period. We expect our research and development expenses to continue to decrease over the remainder of this year on a comparative basis primarily as a result of the termination of research services provided to the Genomics Center. General and administrative expenses decreased to $2,349,000 for the nine months ended September 30, 2000 compared to $2,564,000 for the corresponding period in 1999 primarily due to decreased professional and legal services incurred principally in connection with litigation and a private placement offering that was canceled in 1999. 9 12 We incurred interest expense of $173,000 for the nine months ended September 30, 2000 compared to $386,000 for the corresponding period in 1999. The decrease resulted from a lower level of long-term debt during the period. OPERATING RESULTS We incurred losses of $9,999,000 for the nine months ended September 30, 2000 and $17,017,000 for the corresponding period in 1999, or $.40 and $.78 per share, respectively. We expect that substantial operating losses will continue for several more years but will decrease over the remainder of this year (exclusive of the gain on sale of the Genomics Center) as a result of the sale of our interest in the Genomics Center. However, operating losses are expected to increase thereafter as our product development activities expand and are expected to fluctuate as a result of differences in the timing and composition of revenue earned and expenses incurred. LIQUIDITY AND CAPITAL RESOURCES We have financed our operations and investments primarily through the private placement and public offering of our securities, including the sale of common stock to Acqua Wellington North American Equities Fund, Ltd. ("Acqua Wellington"), the sale of series C preferred stock to investors and the sale of series B preferred stock to Aventis, as well as the exercise of stock options and warrants, supplemented by the issuance of long-term debt, operating and capital lease transactions, interest income, government-sponsored research grants, research revenue under the 1995 Osteoporosis Agreement, research revenue under the terms of our services agreements with the Genomics Center and, in December 1999, the sale to Aventis of our 50% interest in the Genomics Center. On June 27, 2000 we entered into a definitive agreement with Acqua Wellington for an equity financing facility ("Equity Facility") providing for the sale from time to time of up to $75,000,000 of the Company's common stock over an 18 month period. Pursuant to the terms of the Equity Facility, on October 12, 2000, we completed the sale of 176,173 common shares to Acqua Wellington at a price of $12.11 per share and received proceeds of $2,133,000. In addition, on June 27, 2000 we sold to Acqua Wellington 680,851 shares of common stock at $11.75 per share for a total of $8,000,000 in a direct equity placement. At September 30, 2000, we had cash and marketable securities totaling $38,167,000 and working capital of $35,612,000 compared to cash and cash equivalents totaling $28,320,000 and working capital of $22,730,000 at December 31, 1999. The primary uses of cash during the nine months ended September 30, 2000 were $12,166,000 to finance our operations and working capital requirements, $38,666,000 to purchase marketable securities, $186,000 to purchase laboratory equipment, $900,000 to repay long-term debt, and $747,000 to purchase and license intellectual property. The primary source of funds during the nine months ended September 30, 2000, were $8,156,000 from the sales and maturities of marketable securities, $11,638,000 from the exercise of 10 13 warrants, $4,611,000 from the issuance of common stock pursuant to employee stock option and purchase plans and $7,539,000 from the issuance of common stock, net of issuance costs. We have substantial fixed commitments under various research and licensing agreements, consulting and employment agreements, lease agreements and long-term debt instruments. These fixed commitments currently aggregate in excess of $4,600,000 per year and may increase. We will require substantial additional funding for our research and development programs, including preclinical development and clinical trials, for operating expenses, for the pursuit of regulatory clearances and for establishing manufacturing, marketing and sales capabilities. Adequate funds for these purposes, whether obtained through financial markets or collaborative or other arrangements with collaborative partners, or from other sources, may not be available when needed or on terms acceptable to us. We believe that our available funds will be adequate to satisfy our capital and operating requirements through the next two years. However, there can be no assurance that changes in our research and development plans or other events affecting our revenues or operating expenses will not result in the earlier depletion of our funds. SECURITIES LITIGATION REFORM ACT Safe harbor statement under the Private Securities Litigation Reform Act of 1995: Except for the historical information contained in this Quarterly Report on Form 10-Q, the matters discussed herein are forward-looking statements that involve risks and uncertainties, including but not limited to risks and uncertainties regarding our ability to succeed in developing marketable drugs or generating product revenues, our ability to accurately estimate the actual research and development expenses and other costs associated with the preclinical and clinical development of our products, the success of our preclinical studies, our ability to commence clinical studies, the adequacy of our capital resources and the availability of additional funding, as well as general economic, competitive, governmental and technological factors affecting our operations, markets, products, services and prices, and other factors discussed under the heading "Cautionary Statement Regarding Forward-Looking Statements" in our Annual Report on Form 10-K for the year ended December 31, 1999, which has been filed with the Securities and Exchange Commission. As a result of these or other factors, actual events or results could differ materially from those described herein. ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK We own financial instruments that are sensitive to market risks as part of our investment portfolio. The investment portfolio is used to preserve our capital until it is required to fund operations, including our research and development activities. Our marketable securities generally consist of commercial and corporate paper and corporate notes. Substantially all investments mature within one year, are not callable by the issuer and have fixed interest rates and are available for sale. These investments are subject to interest rate risk, and could decline in value if interest rates fluctuate. Due to the conservative nature of our marketable securities, we do not believe that we have a material exposure to interest rate risk. 11 14 At September 30, 2000, we have a bank term note outstanding with an interest rate of prime plus 1%. This note is sensitive to interest rate risk. In the event of a hypothetical 10% increase in the prime rate, or 95 basis points, we would incur approximately $21,000 of additional interest expense per year. PART II. OTHER INFORMATION ITEM 5. OTHER INFORMATION Ms. Tamar Howson, former senior vice president and director, worldwide business development at SmithKline Beecham, plc, was elected as a director of the Company, effective September 1, 2000, to serve with the class of directors whose terms of service expire at the Annual Meeting of Stockholders in 2001. Mr. Jay R. LaMarche, executive vice president, chief financial officer and treasurer of the Company, resigned from these positions effective November 10, 2000 and retired due to health reasons. Mr. LaMarche will continue to serve as a director of the Company. Mr. Brian A. Lajoie, former vice president of finance at Biopure Corporation, a biotechnology company, was appointed interim chief financial officer until a permanent replacement is employed. ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K (a) Exhibits The following exhibits are filed herewith: Exhibit No. Title --- ----- 27.1 Financial Data Schedule (b) Reports on Form 8-K The Company filed one current report on Form 8-K during the quarter ended September 30, 2000. The Form 8-K, dated June 27, 2000 and filed on July 7, 2000, reported that the Company had entered into two common stock purchase agreements for the sale of up to an aggregate of 3,480,851 shares of Common Stock. 12 15 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. ARIAD Pharmaceuticals, Inc. (Registrant) By: /s/ Jay R. LaMarche ----------------------------------------- Jay R. LaMarche Executive Vice President and Chief Financial Officer (Duly authorized Officer and Principal Financial Officer) Date: November 9, 2000 13 16 EXHIBIT INDEX Exhibit No. Title ------- ----- 27.1 Financial Data Schedule 14