Exhibit 16.1 [ANDERSEN LETTERHEAD] Office of the Chief Accountant Securities and Exchange Commission 450 Fifth Street, N.W. Washington, D.C. 20549 March 22, 2002 Dear Sir/Madam: We have read the paragraph titled "Change in Accountants" included in the Amendment # 1 to Form S-1 of Viacell, Inc. to be filed with the Securities and Exchange Commission and are in agreement with the statements contained therein. Very truly yours, /s/ Arthur Andersen LLP - ----------------------- Arthur Andersen LLP DLH Copy To: Ms. Mary Thistle, Vice President of Finance, Viacell, Inc.