Exhibit 23.2


                          CONSENT OF ERNST & YOUNG LLP



We consent to the incorporation by reference in the Registration Statements
(Form S-8 Nos. 333-3898, 333-3900, 333-3902, 333-34008 and 333-71938) and the
related Prospectuses of Hybridon, Inc. of our report dated January 23, 2003
(except for Note 18, as to which date is February 14, 2003), with respect to the
consolidated financial statements of Hybridon, Inc. included in the Annual
Report (Form 10-K) for the year ended December 31, 2002.


                                                  /s/ Ernst & Young LLP


Boston, Massachusetts
March 25, 2003