Exhibit 23.2


                        CONSENT OF INDEPENDENT AUDITORS


We consent to the reference to our firm under the caption "Experts" in Amendment
No. 1 to the Registration Statement (Form S-2 on Form S-3/A No. 333-109630) and
related Prospectus of Hybridon, Inc. and to the incorporation by reference
therein of our report dated January 23, 2003 (except for Note 18, as to which
the date is February 14, 2003) with respect to the consolidated financial
statements of Hybridon, Inc. as of and for the year ended December 31, 2002
included in its Annual Report (Form 10-K) for the year ended December 31, 2002,
filed with the Securities and Exchange Commission.


                                              /s/ Ernst & Young LLP

Boston, Massachusetts
December 3, 2003