Exhibit 32.2

         CERTIFICATION OF CHIEF FINANCIAL OFFICER PURSUANT TO 18 U.S.C.
             SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE
                           SARBANES-OXLEY ACT OF 2002

      In connection with the Annual Report on Form 10-K of Boston Scientific
Corporation (the "Company") for the period ending December 31, 2004 as filed
with the Securities and Exchange Commission on the date hereof (the "Report"),
the undersigned Chief Financial Officer of the Company hereby certifies,
pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, that based on his knowledge:

(1)   the Report fully complies with the requirements of Section 13 (a) or 15
      (d) of the Securities Exchange Act of 1934; and

(2)   the information contained in the Report fairly presents, in all material
      respects, the financial condition and results of operations of Boston
      Scientific Corporation.

By: /s/ Lawrence C. Best
   -------------------------------------
   Lawrence C. Best
   Executive Vice President - Finance &
   Administration and Chief Financial
   Officer

   Dated: March 15, 2005