. . . EXHIBIT 12.1 BOSTON SCIENTIFIC CORPORATION STATEMENT OF COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES (UNAUDITED) (in millions) Year Ended December 31, ------------------------------------------------ 2004 2003 2002 2001 2000 ------ ------ ------ ------ ------ Fixed charges: Interest expense and debt issuance costs $ 64 $ 46 $ 43 $ 59 $ 70 Interest portion of rental expense 10 10 11 12 15 ------ ------ ------ ------ ------ Total fixed charges 74 $ 56 $ 54 $ 71 $ 85 ====== ====== ====== ====== ====== Earnings: Income before income taxes $1,494 $ 643 $ 549 $ 44 $ 527 Fixed charges per above 74 56 54 71 85 Distributed equity in earnings of equity investees 25 Equity in losses (earnings) of equity investees 3 (13) (12) ------ ------ ------ ------ ------ Total earnings, as adjusted $1,571 $ 699 $ 603 $ 102 $ 625 ====== ====== ====== ====== ====== Ratio of earnings to fixed charges 21.23 12.48 11.17 1.44 7.35 ====== ====== ====== ====== ====== The calculation above relates to the $1,600 million of registered debt securities that the Company has outstanding at December 31, 2004. See Note F of the consolidated financial statements for further information regarding the debt securities.