EXHIBIT 32.1

                                  CERTIFICATION
            PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

      Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a)
and (b) of section 1350, chapter 63 of title 18, United States Code), each of
the undersigned officers of Biogen Idec Inc., a Delaware corporation (the
"Company"), does hereby certify, to such officer's knowledge, that:

      The Quarterly Report on Form 10-Q for the quarter ended March 31, 2005
(the "Form 10-Q") of the Company fully complies with the requirements of Section
13(a) or 15(d) of the Securities Exchange Act of 1934, and the information
contained in the Form 10-Q fairly presents, in all material respects, the
financial condition and results of operations of the Company.

Dated:  April 28, 2005                 /s/ James C. Mullen
                                       ----------------------------------------
                                       James C. Mullen
                                       Chief Executive Officer
                                         and President
                                       [principal executive officer]



Dated:  April 28, 2005                 /s/ Peter N. Kellogg
                                       ----------------------------------------
                                       Peter N. Kellogg
                                       Executive Vice President - Finance
                                         and Chief Financial Officer
                                       [principal financial officer]

      A signed original of this written statement required by Section 906 has
been provided to the Company and will be retained by the Company and furnished
to the Securities and Exchange Commission or its staff upon request.