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                                                      Exhibit 10.32
                                                      -------------


                                  BIOGEN, INC.
                  VOLUNTARY EXECUTIVE SUPPLEMENTAL SAVINGS PLAN

                                 AMENDMENT NO. 1


      WHEREAS, Biogen, Inc. ("Biogen") adopted the Biogen, Inc. Voluntary
Executive Supplemental Savings Plan (the "Plan") effective April 18, 1994,
and

      WHEREAS, Section 7.1 of the Plan permits Biogen, by action of the Board of
Directors of Biogen (or its delegate) to amend the Plan; and

      WHEREAS, Biogen desires to amend the Plan to increase the frequency by
which a participant may change his designation of mutual funds with respect to
which deemed investment results are determined;

      NOW, THEREFORE, the Plan is hereby amended effective May 1, 1997 as
follows:

      Section 5.1 (Participant Accounts) is amended by deleting the second
sentence of the second paragraph of subsection (c) thereof and replacing it with
the following:

      "Thereafter, a participant may change his designation either with respect
      to the deemed investment of future savings deposits and matching credits
      or the deemed transfer of amounts from a previously designated mutual fund
      to another fund. The Committee shall establish the frequency by which such
      a change may be made, the method of making such a change, and the
      effective date of such a change and shall prescribe such other rules and
      procedures as it deems appropriate."

IN WITNESS WHEREOF, Biogen has caused this instrument to be executed by the
individual duly authorized as of the 25th day of April, 1997.

                                         BIOGEN, INC.


                                         By:
                                             -----------------------------------
                                             Frank A. Burke, Jr.
                                             Vice President - Human Resources