1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For Quarter Ended: JUNE 30, 1999 Commission File No. 0-19193 CAMBRIDGE NEUROSCIENCE, INC. ------------------------------------------------------ (Exact name of registrant as specified in its charter) DELAWARE 13-3319074 - ------------------------------- -------------------------- (State or other jurisdiction of (I.R.S. Employer I.D. No.) incorporation or organization) ONE KENDALL SQUARE, BUILDING 700 CAMBRIDGE, MA 02139 ----------------------------------------------------------- (Address of principal executive offices including zip code) 617-225-0600 ---------------------------------------------------- (Registrant's telephone number, including area code) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes X No --- At July 31, 1999, 18,135,964 shares of Common Stock, par value $.001 per share, were issued and outstanding. 2 CAMBRIDGE NEUROSCIENCE, INC. INDEX PAGE PART I - FINANCIAL INFORMATION NUMBER - ------------------------------ ------ ITEM 1 - FINANCIAL STATEMENTS (unaudited) Condensed Consolidated Balance Sheets At June 30, 1999 and December 31, 1998 3 Condensed Consolidated Statements of Operations for the three and six months ended June 30, 1999 and 1998 4 - 5 Condensed Consolidated Statements of Cash Flows for the six months ended June 30, 1999 and 1998 6 Notes to Condensed Consolidated Financial Statements 7 - 8 ITEM 2 - MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS 8 - 14 ITEM 3 - QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK 14 PART II - OTHER INFORMATION - --------------------------- ITEM 4 - SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS 15 ITEM 6 - EXHIBITS AND REPORTS ON FORM 8-K 15 SIGNATURES 16 EXHIBIT INDEX 17 2 3 CAMBRIDGE NEUROSCIENCE, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (in thousands, except per share data) June 30, December 31, 1999 1998 --------- ------------ ASSETS (Unaudited) (Note) Current Assets Cash and cash equivalents $ 3,771 $ 4,863 Marketable securities 7,042 7,037 Receivables from collaboration agreements 174 2,080 Prepaid expenses and other current assets 1,314 1,260 --------- --------- Total Current Assets 12,301 15,240 Equipment, Furniture and Fixtures, net 290 377 --------- --------- Total Assets $ 12,591 $ 15,617 ========= ========= LIABILITIES AND STOCKHOLDERS' EQUITY Current Liabilities Accounts payable and accrued expenses $ 719 $ 1,637 Research and development advances -- 250 --------- --------- Total Current Liabilities 719 1,887 Stockholders' Equity Preferred stock, par value $.01, 10,000 shares authorized; none issued -- -- Common stock, par value $.001, 30,000 shares authorized; 18,136 shares issued and outstanding at June 30, 1999; 18,085 at December 31, 1998 18 18 Additional paid-in capital 120,119 120,088 Accumulated deficit (108,265) (106,376) --------- --------- Total Stockholders' Equity 11,872 13,730 --------- --------- Total Liabilities and Stockholders' Equity $ 12,591 $ 15,617 ========= ========= Note: The balance sheet at December 31, 1998 has been derived from the audited financial statements at that date, but does not include all of the information and footnotes required by generally accepted accounting principals for complete financial statements. The accompanying notes are an integral part of the condensed consolidated financial statements. 3 4 CAMBRIDGE NEUROSCIENCE, INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (in thousands, except per share data) (unaudited) Three months ended June 30, --------------------------- 1999 1998 ------- ------- Revenues Research and development $ 490 $ 250 Operating expenses Research and development 1,195 1,585 General and administrative 314 426 ------- ------- 1,509 2,011 ------- ------- Loss from operations (1,019) (1,761) Interest income 136 265 ------- ------- Net loss $ (883) $(1,496) ======= ======= Basic and diluted net loss per share $ (0.05) $ (0.08) ======= ======= Shares used in computing basic and diluted net loss per share 18,100 17,924 ======= ======= The accompanying notes are an integral part of the condensed consolidated financial statements. 4 5 CAMBRIDGE NEUROSCIENCE, INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (in thousands, except per share data) (unaudited) Six months ended June 30, ------------------------- 1999 1998 ------- ------- Revenues Research and development $ 872 $ 551 Operating expenses Research and development 2,434 3,917 General and administrative 633 939 Restructuring cost -- 921 ------- ------- 3,067 5,777 ------- ------- Loss from operations (2,195) (5,226) Interest income 306 786 ------- ------- Net loss $(1,889) $(4,440) ======= ======= Basic and diluted net loss per share $ (0.10) $ (0.25) ======= ======= Shares used in computing basic and diluted net loss per share 18,100 17,907 ======= ======= The accompanying notes are an integral part of the condensed consolidated financial statements. 5 6 CAMBRIDGE NEUROSCIENCE, INC. CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (in thousands) (unaudited) Six months ended June 30, ------------------------- 1999 1998 ------- -------- Operating Activities Net loss $(1,889) $ (4,440) Items not requiring cash: Depreciation and amortization 96 185 Common stock issued pursuant to an employee benefit plan -- 103 ------- -------- (1,793) (4,152) Changes in current assets and liabilities: Receivables from collaboration agreements 1,906 Prepaid expenses and other current assets (54) 511 Accounts payable and accrued expenses (918) (1,290) Research and development advances (250) (250) ------- -------- 684 (1,029) ------- -------- Cash used for operating activities (1,109) (5,181) Investing Activities Purchases of marketable securities (3,782) (8,996) Sales of marketable securities 3,777 30,539 Purchase of equipment, furniture and fixtures, net of disposals (9) (11) ------- -------- Cash (used for) provided by investing activities (14) 21,532 Financing Activities Sale of common stock 31 38 Dividend -- (17,907) ------- -------- Cash provided by (used for) financing activities 31 (17,869) Net Increase in Cash and Cash Equivalents (1,092) (1,518) Cash and Cash Equivalents at beginning of period 4,863 12,020 ------- -------- Cash and Cash Equivalents at end of period $ 3,771 $ 10,502 ======= ======== The accompanying notes are an integral part of the condensed consolidated financial statements. 6 7 CAMBRIDGE NEUROSCIENCE, INC. NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) 1. BASIS OF PRESENTATION The accompanying unaudited condensed consolidated financial statements as of June 30, 1999 and for the three and six month periods ended June 30, 1999 and 1998 have been prepared in accordance with generally accepted accounting principles for interim financial information and with the instructions to Form 10-Q. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, the accompanying consolidated financial statements include all adjustments, consisting of normal recurring adjustments, necessary for a fair presentation of the financial position, results of operations and cash flows for the periods presented. The results of operations for the interim period ended June 30, 1999 are not necessarily indicative of the results expected for the full fiscal year. The condensed consolidated financial statements presented as of December 31, 1998 are derived from the audited consolidated financial statements and footnotes included in the Company's Annual Report on Form 10-K (file number 0-19193). Cambridge NeuroScience, Inc. (the "Company") is a biopharmaceutical company engaged in the discovery and development of proprietary pharmaceuticals to prevent or treat severe disorders of, or injuries to, the nervous system. 2. BASIC AND DILUTED NET LOSS PER SHARE Net loss per share is based on the weighted-average number of common shares outstanding during each of the periods presented. Due to the fact that the Company continues to be in a net loss position, common equivalent shares from stock options are excluded as their effect is antidilutive. 3. RESEARCH AND DEVELOPMENT REVENUE The Company recognizes research and development revenue as earned and such revenue represents reimbursement of the Company's expenditures pursuant to the terms of its collaboration and license agreements and government grants. Research and development revenue meets the criteria of being earned when all of the following have occurred: all obligations of the Company relating to the revenue have been met; cash received or receivable is not refundable irrespective of whether the research efforts are successful; and the Company is not obligated to meet future milestones. Revenue from government grants is recorded as earned based on the performance requirements of each respective grant. Expenses relating to collaboration and license agreements and to the performance of government grants are recorded as research and development expenses. Cash received in advance of research and development performed pursuant to the Company's research and development agreements is designated as research and development advances and is included in current liabilities. In November 1996, the Company entered into a collaboration agreement with Allergan, Inc. ("Allergan") for the development of treatments for ophthalmic disorders, including glaucoma. Pursuant to this agreement, Allergan is providing $3.0 million in research funding over a three year period through November 1999. In December 1998, the Company entered into a collaborative agreement with Bayer AG ("Bayer") for the development of recombinant human Glial Growth Factor 2 ("GGF2") for the treatment of neurodegenerative diseases such as multiple sclerosis. The Company received an upfront licensing fee 7 8 CAMBRIDGE NEUROSCIENCE, INC. NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED) of $1.0 million and will receive an additional $1.0 million in reimbursements for research expenses incurred relating to a research protocol covered by the agreement. As of June 30, 1999, the Company has received $777,000 of this research reimbursement. 4. NEW ACCOUNTING PRINCIPLE In June 1998, the Financial Accounting Standards Board issued Statement No. 133, Accounting for Derivative Instruments and Hedging Activities ("FAS 133"), which is effective for fiscal years beginning after June 15, 2000. The Company believes the adoption of this new accounting standard will not have a significant effect on its financial statements. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS RESULTS OF OPERATIONS THREE MONTHS ENDED JUNE 30, 1999 AND 1998 Revenues Research and development revenues in the three months ended June 30, 1999 increased by $240,000 compared to the same quarter of 1998. This increase was due to revenue earned under the collaboration with Bayer, which was entered into in December 1998. Total revenue in the second quarter of 1999 was comprised of the Bayer revenue and $250,000 under the Allergan collaboration. The Allergan revenue is comparable with the amount earned in the second quarter of last year. Operating Expenses Total operating expenses in the three months ended June 30, 1999 decreased by $502,000 compared to the same period in 1998, a decrease of 25%. This was primarily due to a restructuring implemented in the first half of 1998 to focus resources on programs funded by collaborative partners. The restructuring resulted in reduced payroll, facilities and external research costs. During the second quarter of 1999, the Company averaged 17 full-time employees, approximately 29% lower than a year ago. Research and development expenses decreased by $390,000, and general and administrative expenses decreased by $112,000 as compared to last year's second quarter. These decreases were a result of the restructuring described above and attrition. Interest Income Interest income for the quarter ended June 30, 1999 was lower by $129,000 than that in the same period in 1998, as a result of lower cash, cash equivalents and marketable securities available for investment, due primarily to a dividend payment of $17.9 million to shareholders in April 1998 and cash used for operating purposes. 8 9 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED Net Loss Per Share For the quarter ended June 30, 1999, the Company's net loss and net loss per share were approximately 40% lower than in the same period last year, as a result of higher research and development revenue and lower operating expenses, both as described earlier. SIX MONTHS ENDED JUNE 30, 1999 AND 1998 Revenues In the six months ended June 30, 1999, the Company's research and development revenues increased by $321,000 as compared to the same period in 1998, an increase of 58%. This increase was due to revenue earned under the Bayer collaboration totaling $372,000 during the first six months of 1999. Revenues in the first half of 1999 and 1998 included $500,000 under the Allergan collaboration. During the first half of last year, the Company also had a Small Business Innovation Research Grant, accounting for $50,000 in revenue. Operating Expenses In the first half of 1999, the Company's total operating expenses decreased by $2.7 million, or 47% as compared to the same period of last year. Research and development expenses decreased by $1.5 million or 38%, and general and administrative expenses decreased by $306,000 or 33% as compared to the same period of last year. These decreases were attributable primarily to lower payroll, facilities and external research costs as a result of a restructuring program implemented during the first half of 1998. In addition the 1998 period included $921,000 of restructuring charges relating to severance costs. Interest Income Interest income decreased by $480,000, or 61%, compared to the same period in 1998. This decrease was a result of the decrease in cash available for investment following the payment of a dividend totaling $17.9 million in April 1998 and cash used for operating activities. Net Loss Per Share In the first half of 1999, the Company's net loss per share was 60% lower than that of a year ago. This decrease in net loss per share was the result of higher research and development revenues and lower operating expenses. LIQUIDITY AND CAPITAL RESOURCES At June 30, 1999, the Company had cash, cash equivalents and marketable securities of $10.8 million, compared to $11.9 million at December 31, 1998, a decrease of $1.1 million. The decrease was the result primarily of net cash used for operating activities. In December 1998, the Company and Bayer entered into an agreement whereby Bayer licensed the development and manufacturing rights to GGF2 for the treatment of multiple sclerosis and peripheral neuropathies. In exchange, the Company received a $1.0 million license fee in January 1999, and will 9 10 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED receive up to $1.0 million for reimbursement of costs under a research protocol covered by the agreement. Through June 30, 1999, the Company has received $777,000 of this $1.0 million and anticipates receiving the remaining $223,000 during the balance of 1999. The Company may also receive up to $24.0 million in milestone payments. However, there can be no assurance as to when or if any milestones will be achieved. Under terms of the agreement, Bayer is responsible for the manufacture and development of GGF2, and all costs associated therewith. Bayer may terminate this agreement at any time upon 120 days written notice. Pursuant to a collaborative agreement with Allergan, the Company is to receive a total of $3.0 million in research funding, $1.0 million per year, through November 1999. Through June 30, 1999, the Company has received $2.6 million of the total $3.0 million, and expects to receive the remaining $400,000 during the second half of 1999. Under this agreement, Allergan is responsible for the development of potential products and will bear all associated costs. The collaboration also provides that the Company may receive up to an additional $18.5 million upon the achievement of certain milestones. However, there can be no assurance as to when or if these milestones will be achieved. Allergan may terminate this agreement upon six months prior written notice. In December 1996, the Company formed a subsidiary, Cambridge NeuroScience Partners, Inc. ("CNPI"), to pursue the development of treatments for Alzheimer's disease and other neurological disorders. CNPI entered into a collaboration agreement with the J. David Gladstone Institutes ("Gladstone"). Pursuant to this collaboration, Gladstone is conducting a research program over a three year period for which CNPI is providing $1.25 million in funding per year through December 1999. The Company owns 80% of the outstanding stock of CNPI and has guaranteed CNPI's obligations with respect to its collaboration with Gladstone. To date, the minority shareholders have not made equity investments in CNPI. As a result, the entire net loss of CNPI has been attributed to the Company. During the first quarter of 1999, the Company and two outside stroke research groups designed a new phase III clinical trial for aptiganel, the Company's lead stroke candidate, focused on a subset of the stroke patient population. In addition, the two outside stroke researchers collaborated on a grant application to the National Institutes of Health to fund this new phase III study. Based on preliminary feedback received by the outside researchers, the grant will not be funded. As a result, the Company is continuing to explore other funding opportunities for the further development of aptiganel. Further development of aptiganel may require substantial expenditures by the Company, and require the Company to reduce spending on its other research programs. There can be no assurance that further development of aptiganel will occur or that funding for such development will be available or sufficient to complete such development. The Company is continuing to evaluate alternatives for maximizing shareholder value, which may include the sale of some or all of the Company's technology and other assets or a merger with another company. The Company believes that its cash, cash equivalents and marketable securities as of June 30, 1999 will be sufficient to maintain operations through 2000. 10 11 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED YEAR 2000 PROBLEM The Company is aware of the issues that many computer systems will face as the year 2000 approaches. These issues are the result of computer programs having been written using two digits rather than four digits to define the applicable year. Computer hardware and software that have time-sensitive operating data may recognize a date of "00" as the year 1900 rather than the year 2000, resulting in system failures or miscalculations. State of Readiness The following paragraphs describe the Company's state of readiness relating to the year 2000 issue, including the Company's formal plan for addressing the issue, a review of progress made to date, and the estimated dates for completion of each phase of the plan. The phrase "In-house Systems" will be used in the discussion, and is defined as the Company's: i.) computer hardware and software, ii.) computer-aided laboratory equipment, and iii.) computer-aided office equipment, including telephones and security systems. All of these items were purchased from third-party manufacturers or suppliers. The Company has no internally manufactured or developed computers or computer-related hardware or software. The Company's evaluation of the year 2000 issue covers both: i.) In-house Systems, and ii.) service providers. The Company's plan with respect to its In-house Systems is comprised of three phases: inventory and assessment; remediation; and testing and implementation. Inventory and Assessment: The inventory and assessment phase of this process involves the identification of all of the Company's In-house Systems and determining which of them may be impacted by the year 2000 problem and require repair, upgrade or replacement. This entails performing initial tests of each component of hardware and software and/or asking manufacturers of such components whether their systems are currently year 2000 compliant or whether they require modification to become compliant. As of June 30, 1999, the Company had completed approximately 95% of its inventory and assessment. The Company has completed the inventory and assessment of its personal and network computers, its general operating software, its accounting and administrative software, and its computer-aided office equipment and systems. The Company has completed an inventory and has essentially completed the assessment of its laboratory equipment, and is awaiting feedback from manufacturers on two pieces of laboratory equipment. The inventory and assessment of all systems is expected to be completed by August 15, 1999. Remediation: Remediation entails repairing, upgrading or replacing equipment or software that is not compliant. Based on the results of the inventory and assessment, approximately half of the Company's laboratory equipment needed repair or modification. The majority of the Company's personal and network computers and operating systems also required minor repair or upgrade in order to become compliant, as did certain of the Company's office equipment and administrative software. Remediation of all personal 11 12 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED and network computers and operating systems has been completed. Remediation of non-compliant laboratory equipment, office systems, and administrative software is approximately 90% complete, and is scheduled to be completed by August 31, 1999. Testing and Implementation: This will include testing all repaired, replaced and new In-house Systems to determine that they are working properly and adequately address the year 2000 issues identified. All personal and network computers and operating systems have been tested and are deemed compliant. The Company expects to complete this phase of its year 2000 plan and have all systems fully operational by September 1999. Third-Party Service Providers: The Company's major service providers that may be impacted by the year 2000 issue are as follows: i.) banks and financial institutions, ii.) administrative services such as transfer agent and payroll agent, iii.) utility services such as electricity, heat, water and telephone, and iv.) external research and development services. To evaluate the readiness of its third-party service providers, the Company has contacted and reviewed written literature from each provider to ascertain whether the services they provide are at risk of being non-compliant, whether the providers are addressing this issue and what their plans are for resolving any issues. To date, the Company has completed the assessment of approximately 90% of its third-party service providers, but is still awaiting letters of compliance from some. The Company is monitoring the progress of each service provider. The identification of alternative vendors of services is being considered in the course of this process and in the development and implementation of a contingency plan. Costs The Company does not expect to incur material costs to evaluate and resolve any year 2000 problems. The Company may contract with outside consultants at various times during this process to ensure the timely completion of the project. The Company expects to upgrade or replace certain systems supporting the administrative functions and facilities and may have to replace some of the software or equipment used in its research operations. Based on information available at this time, the Company estimates that it will spend between $25,000 and $50,000 to complete the process of resolving the year 2000 problem. These expenditures will be funded from existing cash resources and will not have a material impact on the amount of funds available for other operating purposes. The Company has not incurred material outside costs to date related to repairing, upgrading or replacing equipment to become compliant. The actual costs to be incurred by the Company will depend on a number of factors which cannot be accurately predicted, including the availability and cost of consultants and the extent and difficulty of the remediation and other work to be done. Risks In the event that no further progress is made on the remediation of any year 2000 problems, the Company may experience interruptions in the processing of certain data generated by the Company's research activities. The Company is aware of certain pieces of computer-aided research and discovery 12 13 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED equipment that are not compliant, which could cause the Company to revert to manual laboratory testing procedures and/or outsourcing for these services. The Company expects to have completed all phases of this project before the end of 1999 and does not believe that the existence of significant unresolved year 2000 problems will result in the prolonged and material interruption of its daily operations, including the conduct of its research and development activities. However, there can be no assurance that the Company will complete the remediation of any year 2000 problems on a timely basis or that any unresolved problems would not have an adverse impact on the Company's ability to continue operations and fulfill its obligations pursuant to research and development collaboration agreements. The Company has certain relationships with third parties, including utility providers, financial institutions, vendors and other service providers. The Company believes that with the exception of its utility providers, its relationships with vendors and service providers are not exclusive or material. Consequently, the Company believes that, in the event of a failure on the part of these third parties to become year 2000 compliant on a timely basis, the Company would be able to continue to maintain operations, including the conduct of most of its research and development activities, utilizing alternative vendors where necessary. An interruption of the Company's utility services could materially affect the Company's research, development and administrative operations until such time that those utility services are resumed. There can be no assurance that any third-party service provider engaged by the Company will achieve year 2000 compliance on a timely basis, or that any lack of compliance on the part of such provider will not materially affect the Company's operations. The identification of alternative vendors of services and supplies will be considered in the course of this process and in the development and implementation of a contingency plan. Contingency plan The Company has developed a contingency plan to address what it believes is the major risk associated with the year 2000 problem, the failure of electrical power to the Company's facility. In regards thereto, the Company has developed an emergency response plan to ensure the Company's In-house systems are safeguarded against data loss or malfunction and that any freezers containing key research material do not fail. The Company has an emergency generator powered by natural gas which will be available should there be a temporary electrical power outage. As long as any potential electrical power outage is temporary, the Company's operations should not be materially affected. If the outage is other than temporary, in all likelihood the Company will be unable to resume research activities until such power is restored. The Company is in the process of establishing contingency plans to identify alternative research testing methods, recordkeeping and third-party services in the event of other potential year 2000 problems. The Company expects to have established this plan, to the extent deemed necessary, before the end of 1999. The Company does not believe that inflation has had a material impact on its results of operations. The discussion contained in this section as well as elsewhere in this Quarterly Report on Form 10-Q may contain forward-looking statements based on the current expectations of the Company's management. The Company cautions readers that there can be no assurance that the actual results or 13 14 CAMBRIDGE NEUROSCIENCE, INC. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS, CONTINUED business conditions will not differ materially from those projected or suggested in the forward-looking statements as a result of various factors, including, but not limited to, the following: uncertainties relating to the Company's product candidates; uncertainties as to the Company's ability to continue operations and achieve profitability; the early stage of development of all of the Company's product candidates; the Company's reliance on current and prospective collaborative partners to supply funds for research and development and to commercialize its products; technical risks associated with the development of new products; the competitive environment of the biotechnology and pharmaceutical industries, and the Company's ability to resolve potential year 2000 problems on a timely basis. Readers are cautioned not to place undue reliance on these forward-looking statements which speak only as of the date hereof. The Company undertakes no obligation to publicly release the result of any revisions to these forward-looking statements which may be made to reflect events or circumstances occurring after the date hereof or to reflect the occurrence of unanticipated events. ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK The information required by Item 3 is not provided as the disclosure requirements are not applicable to the Company pursuant to Item 305(e) of Regulation S-K. 14 15 CAMBRIDGE NEUROSCIENCE, INC. PART II - OTHER INFORMATION ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS. At the Company's Annual Meeting of stockholders held on Wednesday, June 3, 1999, the following individuals were elected directors of the Company: Votes --------------------------------------------------------- --------------------- Nominees For Against Abstentions Broker Non-Votes -------- --- ------- ----------- ---------------- Nancy S. Amer 12,045,440 123,971 0 2,840,671 Burkhard Blank 11,971,990 197,421 0 2,840,671 Ira A. Jackson 11,954,618 214,793 0 2,840,671 Joseph B. Martin 11,776,580 392,831 0 2,840,671 Paul C. O'Brien 11,765,358 404,053 0 2,840,671 Harry W. Wilcox, III 11,984,140 185,271 0 2,840,671 ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K (a) Exhibits 3.1 Amended and restated Bylaws of the Company as of June 4, 1999 27.1 Financial Data Schedule for the interim year-to-date period ended June 30, 1999 (for electronic filing only) (b) Reports on Form 8-K None. 15 16 CAMBRIDGE NEUROSCIENCE, INC. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. CAMBRIDGE NEUROSCIENCE, INC. Date August 10, 1999 /s/ Harry W. Wilcox, III ------------------------ -------------------------------------- Harry W. Wilcox, III President and Chief Executive Officer (Principal Executive Officer; Acting Principal Financial Officer) Date August 10, 1999 /s/ Glenn A. Shane ------------------------ -------------------------------------- Glenn A. Shane (Principal Accounting Officer) 16 17 CAMBRIDGE NEUROSCIENCE, INC. EXHIBIT INDEX Exhibit Number Description - ------ ----------- 3.1 Amended and restated Bylaws of the Company as of June 4, 1999 27.1 Financial Data Schedule for the interim year-to-date period ended June 30, 1999 (for electronic filing only) 17