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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-K/A
                                 AMENDMENT NO. 1

                [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

   For the fiscal year ended December 31, 2000 Commission File Number 0-22333

                       NANOPHASE TECHNOLOGIES CORPORATION
             (Exact name of registrant as specified in its charter)

             DELAWARE                                    36-3687863
  (State or other jurisdiction              (I.R.S. Employer Identification No.)
of incorporation or organization)

                1319 MARQUETTE DRIVE, ROMEOVILLE, ILLINOIS 60446
               (Address of principal executive offices) (zip code)

       Registrant's telephone number, including area code: (630) 323-1200

        Securities registered pursuant to Section 12(b) of the Act: NONE

           Securities registered pursuant to Section 12(g) of the Act:
                     COMMON STOCK, PAR VALUE $.01 PER SHARE
                         PREFERRED STOCK PURCHASE RIGHTS


     Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days. Yes X    No
                                             ---     ---

     Indicate by check mark if disclosure of delinquent filers pursuant to
Item 405 of Regulation S-K is not contained herein, and will not be contained,
to the best of registrant's knowledge, in definitive proxy or information
statements incorporated by reference in Part III of this Form 10-K or any
amendment to this Form 10-K. Yes    No X
                                ---   ---

     The aggregate market value of the registrant's voting stock held by
non-affiliates of the registrant, based upon the last reported sale price of the
registrant's Common Stock on March 20, 2001 was $84,709,008.

     The number of shares outstanding of the registrant's Common Stock, par
value $.01, as of March 20, 2001 was 13,621,549.

                       DOCUMENTS INCORPORATED BY REFERENCE

     Portions of the registrant's Definitive Proxy Statement in connection
with the registrant's 2001 Annual Meeting of Stockholders to be held on June 5,
2001 are incorporated by reference into Part III of this Report on Form 10-K, as
amended hereby.
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     We are filing this amendment to our Annual Report of Form 10-K to correct
a typographical error in Item 6 of Part II. In the previous filing, the year
2000 net loss number was stated as $4,518,327 in the selected financial data
schedule in Item 6. The correct number as properly reported elsewhere in the
previous filing is ($4,518,327), as set forth below.

ITEM 6.  SELECTED FINANCIAL DATA

     The following selected financial data is qualified by reference to, and
should be read in conjunction with, the financial statements and related notes
thereto appearing elsewhere in this Form 10-K and "Item 7. Management's
Discussion and Analysis of Financial Condition and Results of Operations." The
selected financial data set forth below as of, and for, each of the years in the
five-year period ended December 31, 2000 have been derived from the audited
financial statements of the Company.




                                                                     YEARS ENDED DECEMBER 31,
                                               -------------------------------------------------------------------
                                                   2000          1999          1998         1997          1996
                                               -------------------------------------------------------------------
                                                                                        
STATEMENT OF OPERATIONS DATA:
Product revenue............................    $ 3,824,159   $ 1,128,861   $ 1,140,845   $   924,763   $   249,017
Other revenue..............................        449,194       295,986       162,944     2,798,729       236,019
Governmental research contracts............             --            --            --            --       110,770
                                               -----------   -----------   -----------   -----------   -----------
Total revenue..............................      4,273,353     1,424,847     1,303,789     3,723,492       595,806
Cost of revenue............................      4,754,485     2,610,667     3,221,996     3,935,766     4,019,484
Research and development expense...........      1,837,036     1,456,126     1,504,127       990,331       677,284
Selling, general and administrative expense      3,388,758     3,641,736     3,594,946     2,074,728     1,661,504
                                               -----------   -----------   -----------   -----------    ----------
Total operating expense....................      9,980,279     7,708,529     8,321,069     7,000,825     6,358,272
                                               -----------   -----------   -----------   -----------    ----------
Operating loss.............................     (5,706,926)   (6,283,682)   (7,017,280)   (3,277,333)   (5,762,466)
Interest income............................      1,188,599     1,166,615     1,539,400       204,863       184,778
Provision for income taxes.................             --            --      (156,000)           --            --
                                               -----------   -----------   -----------   -----------   -----------
Net loss...................................    $(4,518,327)  $(5,117,067)  $(5,633,880)  $(3,072,470)  $(5,577,688)
                                               ===========   ===========   ===========   ===========   ===========
Net loss per share-basic and diluted.......    $     (0.34)  $     (0.40)  $     (0.45)
                                               ===========   ===========   ===========
Shares used in computing the net loss per
share......................................     13,390,741    12,690,483    12,416,305





                                               ----------------------------------------------------------------------
                                                                           AS OF DECEMBER 31,
                                               ----------------------------------------------------------------------
                                                    2000         1999         1998         1997           1996
                                               ----------------------------------------------------------------------
                                                                                        
BALANCE SHEET DATA:
Cash and cash equivalents..................    $   473,036   $   624,509   $   363,394   $ 3,988,368   $   617,204
Working capital............................     18,356,349    21,831,264    26,535,018    32,038,915     3,070,789
Total assets...............................     23,830,163    25,677,539    30,453,988    36,196,569     5,539,634
Total stockholders' equity.................     21,007,745    24,161,323    29,107,590    34,651,334     5,110,450





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                                   SIGNATURES

     Pursuant to the requirements of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized, on the 11th day of
April, 2001.

                               NANOPHASE TECHNOLOGIES CORPORATION


                                     By:   /s/ Joseph Cross
                                        ----------------------------------------
                                           Joseph Cross
                                           President and Chief Executive Officer