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            SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

                              --------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                              --------------------

                              Biomune Systems, Inc.
                       -----------------------------------
             (Exact name of registrant as specified in its charter)
           Nevada                                         87-0380088
   -----------------------                  ------------------------------------
 (State or other jurisdiction)              (I.R.S. Employer Identification No.)
incorporation or organization)

                             6502 South Archer Road
                          Bedford Park, Illinois 60501
                                 (708) 563-9200
                           --------------------------
                    (Address of Principal Executive Offices)

                              Consulting Agreement
                           --------------------------
                            (Full title of the plan)

                       Larry P. Koskan, President and CEO
                              Biomune Systems, Inc.
                             6502 South Archer Road
                          Bedford Park, Illinois 60501
                          -----------------------------
                     (Name and address of agent for service)

                                 (708) 563-9200
          (Telephone number, including area code, of agent for service)
                              --------------------

                                    Copy to:
                          Stephen J. Greenberg, Esquire
                          Duane, Morris & Heckscher LLP
                                One Liberty Place
                           Philadelphia, PA 19103-7396

                         CALCULATION OF REGISTRATION FEE


======================================================================================================

Title of securities     Amount to be       Proposed             Proposed               Amount of
 to be registered        registered    maximum offering     maximum aggregate     registration fee (2)
                                      price per share(1)    offering price(1)
- ------------------------------------------------------------------------------------------------------
                                                                            
Common Stock, par    1,000,000 shares      $1.35               $1,350,000               $356.40
value $0.0001/share
======================================================================================================


(1)    Pursuant to paragraph (C) of Rule 457, the proposed maximum offering
       price per share and the proposed maximum aggregate offering price have
       been computed on the basis of $1.35 per share, the average of the high
       and low sales prices of the Common Stock of the Company on the Over the
       Counter Bulletin Board on April 27, 2001 (within 5 business days prior
       to the date of filing the registration statement).

(2)    $264 per $1,000,000 of aggregate offering price, pursuant to Section 6(b)
       of the Securities Act of 1933.


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                                     PART I

              INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS

         The documents containing the information specified in Part I of this
Registration Statement will be sent or given to the consultant as specified by
Rule 428(b)(1). Such documents are not required to be and are not filed with the
Securities and Exchange Commission (the "Commission") either as part of this
Registration Statement or as prospectuses or prospectus supplements pursuant to
Rule 424. These documents and the documents incorporated by reference in this
Registration Statement pursuant to Item 3 of Part II of this Form S-8, taken
together, constitute a prospectus that meets the requirements of Section 10(a)
of the Securities Act of 1933, as amended (the "Securities Act").

                                     PART II

                 INFORMATION REQUIRED IN REGISTRATION STATEMENT

ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE.

     The following documents filed with the Commission by Biomune Systems, Inc.
(the "Company") are incorporated herein by reference:

     a. The Company's Annual Report on Form 10-K for the fiscal year ended
December 31, 2000; and

     b. Description of the class of securities of the Company to be offered,
(incorporated by reference to the Registration Statement of the Company
previously filed, pursuant to which the class of Common Stock of the Company was
registered under the Securities Exchange Act of 1934, as amended).

     All documents subsequently filed by the Company with the Commission
pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to
the filing of a post-effective amendment to this Registration Statement which
indicates that all securities offered have been sold or which deregisters all
securities then remaining unsold, shall be deemed to be incorporated by
reference in this Registration Statement and to be a part hereof from the date
of filing of such documents.

ITEM 4. DESCRIPTION OF SECURITIES.

        Not applicable.

ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL.

     The validity of the issuance of the shares of Common Stock registered
hereby will be passed upon for the Company by Duane, Morris & Heckscher LLP,
Philadelphia, Pennsylvania.


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ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

     Sections 78-7502 - 78.751 of the Corporation Law of Nevada, together with
Articles 4.15 - 4.17 of the Bylaws of the Company, provide for indemnification
of the Company's directors, officers, employees, fiduciaries or agents, subject
to the Company's determination in each instance that indemnification is in
accordance with the standards set forth in the General Corporation Law and in
the Bylaws. The Company may purchase and maintain liability insurance on behalf
of a person who is or was a director, officer, employee, fiduciary, or agent of
the Company against liability asserted against or incurred by him or her in that
capacity or arising from his or her status as a director, officer, employee,
fiduciary, or agent, whether or not the Company would have power to indemnify
him or her against the same liability under the provisions of the Bylaws. See
Articles 4.15 - 4.17 of the Company's Bylaws, which is incorporated herein by
reference and which qualifies the foregoing summary statement.

     Insofar as indemnification for liabilities arising under the Securities Act
of 1933 may be permitted to directors, officers or persons controlling the
Company pursuant to the foregoing provisions, or otherwise, the Company has been
informed that in the opinion of the Commission such indemnification is against
public policy as expressed in the Act and is therefore unenforceable.

ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED.

        Not applicable.

ITEM 8. EXHIBITS.

     4    Consulting Agreement.

     5    Opinion of Duane, Morris & Heckscher LLP.

     23.1 Consent of Grant Thornton LLP.

     23.2 Consent of Duane, Morris & Heckscher LLP (included with its opinion
          filed as Exhibit 5.

ITEM 9. UNDERTAKINGS.

(a)     The undersigned Registrant hereby undertakes:


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     (1)  To file, during any period in which it offers or sells securities, a
          post-effective amendment to this registration statement:

          (i)  To include any prospectus required by Section 10(a)(3) of the
               Securities Act;

          (ii) To reflect in the prospectus any facts or events arising after
               the effective date of the registration statement (or the most
               recent post-effective amendment thereof) which, individually or
               in the aggregate, represent a fundamental change in the
               information set forth in the registration statement;

         (iii) To include any material information with respect to the plan of
               distribution not previously disclosed in the registration
               statement or any material change to such information in the
               registration statement;

          provided, however, that paragraphs (a)(1)(i) and (a) (1) (ii) do not
          apply if the information required to be included in a post-effective
          amendment by those paragraphs is contained in periodic reports filed
          with or furnished to the SEC by the Registrant pursuant to Section 13
          or Section 15(d) of the Exchange Act that are incorporated by
          reference in the registration statement.

     (2)  That, for the purpose of determining any liability under the
          Securities Act, each such post-effective amendment shall be deemed to
          be a new registration statement relating to the securities offered
          therein, and the offering of such securities at that time shall be
          deemed to be the initial bona fide offering thereof.

     (3)  To remove from registration by means of a post-effective amendment any
          of the securities being registered which remain unsold at the
          termination of the offering.

(b)  The undersigned Registrant hereby undertakes that, for purposes of
     determining any liability under the Securities Act, each filing of the
     Registrant's annual report pursuant to Section 13(a) or Section 15(d) of
     the Exchange Act (and, where applicable, each filing of an employee benefit
     plan's annual report pursuant to Section 15(d) of the Exchange Act) that is
     incorporated by reference in the Registration Statement shall be deemed to
     be a new registration statement relating to the securities offered therein,
     and the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

(c)  Insofar as indemnification for liability arising under the Securities Act
     may be permitted to directors, officers and controlling person of the
     Registrant pursuant to the foregoing provisions, or otherwise, the
     Registrant has been advised that in the opinion of the SEC such
     indemnification is against public policy as expressed in the Securities Act
     and is therefore, unenforceable. In the event that a claim for
     indemnification against such liabilities (other than the payment by the
     Registrant of expenses incurred or paid by a director, officer or
     controlling person of the Registrant in the successful defense of any
     action, suit or proceeding) is asserted by such director, officer or
     controlling person in connection with the securities being registered, the
     Registrant will, unless in the opinion of its counsel the matter has been
     settled by controlling precedent, submit to a court of appropriate
     jurisdiction the question whether such indemnification by it is against
     public policy as expressed in the Securities Act and will be governed by
     the final adjudication of such issue.


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                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in Bedford Park, Illinois on April 25, 2001.

                                                         BIOMUNE SYSTEMS, INC.


                                                         By: /s/ Larry P. Koskan
                                                             -------------------
                                                         Larry P. Koskan
                                                         President and Chief
                                                         Executive Officer


         Pursuant to the requirements of the Securities Act of 1933, as amended,
this Registration Statement has been signed below by the following persons in
the capacities and on the date indicated.

Signature                          Title                      Date


 /s/ Larry P. Koskan               Director, Chairman         April 25, 2001
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     Larry P. Koskan


 /s/ Robert E. Cooper              Director                   April 25, 2001
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     Robert W. Cooper


 /s/ Dr. Robert G. Martin          Director                   April 25, 2001
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     Dr. Robert G. Martin


                                   Director                   April __, 2001
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     Dean R. Kleckner


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                                  EXHIBIT INDEX


         Exhibit No.   Exhibit Description

               4       Consulting Agreement.

               5       Opinion of Duane, Morris & Heckscher LLP.

            23.1       Consent of Grant Thornton LLP

            23.2       Consent of Duane, Morris & Heckscher LLP (included with
                       its opinion filed as Exhibit 5.