Exhibit 32.1

                    Certification of Chief Executive Officer

     In connection with the Annual Report of Exchange National Bancshares, Inc.
(the "Company") on Form 10-K for the year ended December 31, 2005 as filed with
the Securities and Exchange Commission (the "Report"), I, James E. Smith,
Chairman of the Board and Chief Executive Officer of the Company, hereby certify
in accordance with 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of
the Sarbanes-Oxley Act of 2002, that:

     (a) The Report fully complies with the requirements of Section 13(a) or
15(d) of the Securities Exchange Act of 1934, as amended; and

     (b) The information contained in the Report fairly presents, in all
material aspects, the financial condition and results of operations of the
Company.

Dated: March 16, 2006


                                        /s/ James E. Smith
                                        ----------------------------------------
                                        James E. Smith
                                        Chairman of the Board and Chief
                                        Executive Officer

"A signed original of this written statement required by Section 906 has been
provided to Exchange National Bancshares, Inc. and will be retained by Exchange
National Bancshares, Inc. and furnished to the Securities and Exchange
Commission or its staff upon request."


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