1
                                                                     EXHIBIT 4-D









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                          STOCK AND WARRANT AGREEMENT


                          Dated as of August 11, 1995

                                    between

                          Unimed Pharmaceuticals, Inc.

                                      and

                      Laboratoires Besins Iscovesco, S. A.


                 --------------------------------------------

   2
                               TABLE OF CONTENTS
                          (not part of this Agreement)


                                                                            PAGE

                                                                      
                                   ARTICLE 1

                                  DEFINITIONS                                 1 

                                   ARTICLE 2

                               ISSUANCE OF SHARES                             2
    2.1    Issuance of Shares...............................................  2
    2.2    Closing..........................................................  2
    
                               ARTICLE 3
                                                              
                    AMOUNT AND TERMS OF THE WARRANT                           2
    3.1    Issuance of Warrant..............................................  2
    3.2    Exercise Price...................................................  2
    3.3    Expiration.......................................................  2
    
                                   ARTICLE 4

                              CONDITIONS TO CLOSING                           3
    4.1    Conditions to Investor's Obligations at Closing..................  3
           (a)    Documents and Instruments Delivered at Closing............  3
           (b)    Representations and Warranties True.......................  3
           (c)    Effect of Breach of Warranty or Failure of Condition......  3
    4.2    Conditions to Company's Obligations at Closing...................  3
           (a)    Delivery..................................................  3
           (b)    Representations and Warranties True.......................  3
           (c)    Consents Obtained.........................................  4
           (d)    No Material Adverse Change................................  4
           (e)    Absence of Litigation, Etc. ..............................  4
             
                                   ARTICLE 5
             
                          REPRESENTATIONS AND WARRANTIES                      4
    5.1    Representations and Warranties of the Company at Closing.........  4
           (a)    Existence and Power.......................................  4
           (b)    Subsidiaries..............................................  4
           (c)    Authority, Execution, Delivery and Enforceability.........  4
           (d)    Capital Stock.............................................  4
           (e)    Valid Issuance of Shares..................................  5
           (f)    No Conflicts..............................................  5
           (g)    No Consents Required......................................  5
           (h)    Compliance with Laws......................................  5
           (i)    No Material Adverse Change................................  5
           (j)    Litigation and Adverse Facts..............................  5
           (k)    Exemption From Federal and State Securities Laws..........  5
           (l)    Absence of Default on Material Contracts..................  6
           (m)    Broker's Fees.............................................  6


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                                                                            PAGE
                                                                      
            
           (n)    Registration Rights.......................................  6
    5.2    Representations and Warranties of The Investor...................  6
           (a)    Power, Authority and Authorization........................  6
           (b)    Purchase Entirely for Own Account.........................  6
           (c)    Disclosure of Information.................................  6
           (d)    Investment Experience.....................................  6
           (e)    Accredited Investor.......................................  7
           (f)    Restricted Securities.....................................  7
           (g)    Further Limitations on Disposition........................  7
           (h)    Legends...................................................  7
           (i)    Broker's Fees.............................................  7
            
                                   ARTICLE 6
            
                                   COVENANTS                                  7
    6.1    Maintain Exchange Act Registration and Listing...................  7
    6.2    Perfect Securities Act and Blue Sky Exemptions...................  8
    6.3    Limitation on Other Registration Rights..........................  8
            
                                   ARTICLE 7
            
                                 MISCELLANEOUS                                8
    7.1    Assignments......................................................  8
    7.2    Notices..........................................................  8
    7.3    Execution in Counterparts........................................  9
    7.4    Headings.........................................................  9
    7.5    Exhibit and Schedule References..................................  9
    7.6    Publicity........................................................  9
    7.7    Binding Effect; Governing Law....................................  9
    7.8    Severability.....................................................  9
    7.9    Submission to Jurisdiction.......................................  9


SIGNATURES ................................................................. 10


                                   EXHIBITS:

    Exhibit A     --     Form of Warrant
    Exhibit B     --     Registration Rights Agreement





                                     (ii)
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                          STOCK AND WARRANT AGREEMENT


     THIS STOCK AND WARRANT AGREEMENT (the "Agreement") is made and entered
into as of this 11th day of August, 1995, between UNIMED PHARMACEUTICALS, INC.,
a Delaware corporation  (the "Company") and LABORATOIRES BESINS ISCOVESCO,
S.A., a  corporation organized under the laws of France (the "Investor").

                                R E C I T A L S:

     WHEREAS, the Company and the Investor intend to enter into an agreement
relating to the research, development and licensing of certain pharmaceutical
products owned by Investor; and

     WHEREAS, Investor desires to acquire an equity interest in the Company;
and

     WHEREAS, the Company is willing to issue shares of its common stock to the
Investor, and to issue a warrant to purchase additional shares of common stock,
subject to the terms and conditions of this Agreement;

     NOW, THEREFORE, in consideration of the premises and the mutual covenants
hereinafter contained, and other good and valuable consideration the receipt
and sufficiency of which is hereby acknowledged, Investor and the Company
hereby agree as follows:


                                  ARTICLE 1

                                  DEFINITIONS
                                      
     In addition to the terms defined elsewhere in this Agreement, the
following terms shall have the meanings indicated for purposes of this
Agreement:

     Affiliate as applied to any Person means (a) any other Person directly or
indirectly controlling, controlled by, or under common control with, that
Person or (b) any other Person that owns or controls 5% or more of any class of
equity securities of that Person or any of its Affiliates.

     Closing is defined in Section 2.2.

     Closing Date means August 11, 1995, or such other date as the parties
shall agree shall be the date on which the Closing shall occur.

     Governmental Authority means any federal, state, local, foreign or other
governmental administrative body, instrumentality, department agency, court,
tribunal, administrative hearing body, arbitration panel, commission or other
similar dispute-resolving panel or body.

     License Agreement means that certain License Agreement dated the date
hereof, between the Company and the Investor.

     Material Adverse Effect means, with respect to the Company or any of its
Subsidiaries, any material adverse change (after giving effect to the
transactions contemplated hereby) in the business, operations, prospects,
condition (financial or otherwise), properties or assets of the Company and its
Subsidiaries, taken as a whole, when any such material adverse change is taken
individually or in the aggregate with all other instances in which the
definition of "Material Adverse Effect" is applicable.


   5


     Person means an individual, partnership, corporation (including business
trust), joint stock company, trust, unincorporated association, financial
institution, joint venture or other entity, or a government or any political
subdivision or agency thereof.

     Registration Rights Agreement shall mean that certain Registration Rights
Agreement between the Investor and the Company, in substantially the form of
Exhibit A attached hereto.

     Securities means the Shares and Warrant to be issued to the Investor at
the Closing and the Shares issuable upon exercise of the Warrant.

     Securities Act means the Securities Act of 1933, as amended.

     Shares means the shares of common stock, par value $0.25 per share, of the
Company.

     Subsidiary of any Person means any corporation of which more than 50% of
the outstanding capital stock having ordinary voting power to elect a majority
of the Board of Directors of such corporation (irrespective of whether at the
time stock of any other class or classes of such corporation shall or might
have voting power upon the occurrence of any contingency) is at the time
directly or indirectly owned by such Person, by such Person and one or more of
such Person's other Subsidiaries or by one or more of such Person's other
Subsidiaries.

     Warrant means a warrant of the Company to purchase Shares, in
substantially the form of Exhibit B attached hereto.


                                  ARTICLE 2

                               ISSUANCE OF SHARES

     2.1 Issuance of Shares.  Subject to the terms and conditions of this
Agreement, and in partial consideration of the grant by the Investor of the
license under the License Agreement, the Company agrees to issue to the
Investor, 145,100 Shares, of which 72,600 Shares shall be issued and delivered
five (5) business days after the date hereof, and 72,500 Shares shall be issued
and delivered on January 15, 1996.

     2.2 Closing.  The Closing shall take place at the offices of the Company,
2150 East Lake Cook Road, Buffalo Grove, IL at 10:00 am on the Closing Date, or
at such other time and place as the Company and Investor mutually agree upon
orally or in writing (which time and place are designated as the "Closing").
At the Closing, the Company shall deliver to the Investor a certificate
representing the Shares issued, against delivery of the License Agreement and
the satisfaction by the Investor to all of its obligations which occur at
closing thereunder.




                                  ARTICLE 3

                        AMOUNT AND TERMS OF THE WARRANT

     3.1 Issuance of Warrant.  At the Closing, the Company shall issue to the
Investor a Warrant to purchase 72,550 Shares.

     3.2 Exercise Price.  The exercise price for the Warrant shall be $8.00 per
Share, subject to antidilution and other provisions as set forth in the
Warrant.

     3.3 Expiration.  The Warrant shall expire ten  (10) years after the date of
issue.



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                                  ARTICLE 4

                             CONDITIONS TO CLOSING

     4.1 Conditions to Investor's Obligations at Closing.  The obligation of
Investor to close the transactions contemplated hereby is subject to the
satisfaction of each of the following conditions precedent:

           (a) Documents and Instruments Delivered at Closing.  Investor shall
      have received (except as noted or waived by Investor in writing) the
      following documents and instruments:

                 (i) The Shares to be issued at the Closing Date in the name of
            the Investor;
 
                 (ii)   The Warrant, issued in the name of the Investor;

                 (iii)  Fully executed counterparts of the Registration Rights 
            Agreement;

                 (iv)   Fully executed counterparts of the License Agreement.


                 (v) A certificate of the Company, signed by the Secretary on
            behalf of the Company, as to resolutions of the Company, adopting
            and approving this Agreement and the exhibits hereto, and the
            transactions contemplated hereby and thereby; and

                 (vi) A certificate signed by the Chief Executive Officer and
            Chief Financial Officer of the Company, with respect to the matters
            set forth in Section 4.1(b).

           (b) Representations and Warranties True.  (i) The representations
      and warranties made by the Company herein, in the Registration Rights
      Agreement and the Warrant shall be true and correct in all material
      respects on the Closing Date and (ii) all covenants contained herein and
      in such other agreements to be performed by the Company prior to the
      Closing Date shall have been performed or waived in writing by the
      Investor.


           (c) Effect of Breach of Warranty or Failure of Condition.  In the
      event of any breach of representation or warranty by the Company prior to
      the Closing, of which the Investor has knowledge, or in the event of a
      failure to satisfy any condition to Investor's obligation to the Closing,
      Investor shall have the option of waiving such breach or failure of
      condition and closing the transactions contemplated hereby, or
      terminating this Agreement.  If Investor chooses to terminate this
      Agreement, then no person shall have any rights or obligations hereunder,
      under the Registration Rights Agreement or the Warrant.  If the Investor
      elects to close notwithstanding such breach of warranty or failure of
      condition, then Investor shall not have any claim against the Company for
      breach hereunder with respect to the matter so waived.

     4.2 Conditions to Company's Obligations at Closing.  The obligation of the
Company to close the transactions contemplated by the Closing is subject to the
satisfaction of each of the following conditions precedent:

           (a) Delivery.  The Company shall have received on or prior to the
      Closing Date, a counterpart of the Registration Rights Agreement, License
      Agreement and Supply Agreement, executed by the Investor;

           (b) Representations and Warranties True.  (i) The representations
      and warranties made by the Investor herein and in the Registration Rights
      Agreement shall be true and correct in all material respects on the
      Closing Date and (ii) all covenants contained herein and in the
      Registration Rights Agreement to be performed by the Investor prior to
      the Closing Date shall have been performed the Investor.



                                      3
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           (c) Consents Obtained.  All consents required to be obtained as a
      condition to the Closing shall have been obtained.

           (d) No Material Adverse Change.  Since March 31, 1995, unless
      otherwise disclosed in the Company's filings with the Securities and
      Exchange Commission (the "SEC"), in this Agreement or in a Schedule
      hereto, no event shall have occurred which would have a Material Adverse
      Effect.

           (e) Absence of Litigation, Etc.  No action, suit, investigation,
      proceeding or counterclaim of or before any Governmental Authority or
      other Person is pending or threatened against the Company challenging
      this Agreement or the transactions contemplated hereby or seeking any
      material damages in connection herewith or any judgment, order or
      injunction that would restrain, prohibit or impose materially adverse
      conditions on the transactions contemplated hereby.



                                  ARTICLE 5

                         REPRESENTATIONS AND WARRANTIES

     5.1 Representations and Warranties of the Company at Closing.  The Company
represents and warrants to Investor that on the date hereof and at the Closing:

           (a) Existence and Power.  The Company is (i) a corporation duly
      formed, validly existing and in good standing in the jurisdiction of its
      formation, and has all powers and all governmental licenses,
      authorizations, consents and approvals required to carry on its business
      as now conducted and as proposed to be conducted, except where the
      failure to do any of the above would not have a Material Adverse Effect
      and (ii) duly qualified and authorized to do business and in good
      standing in all jurisdictions where the failure to do so would have a
      Material Adverse Effect.

           (b) Subsidiaries.  Except as set forth in Schedule 5.1(b), each
      material Subsidiary of the Company is a corporation duly organized,
      validly existing, and in good standing under the laws of the state of its
      respective incorporation; and each Subsidiary is duly qualified and in
      good standing as a foreign corporation authorized to do business in each
      jurisdiction where the failure to so qualify would have a Material
      Adverse Effect.

           (c) Authority, Execution, Delivery and Enforceability.  The Company
      has the necessary corporate authority to execute, deliver and perform its
      obligations under this Agreement, the Registration Rights Agreement and
      to consummate the Closing.  The Company has taken all necessary corporate
      action to authorize the execution, delivery and performance of this
      Agreement, Registration Rights Agreement and the Warrant and any other
      documents related thereto.  This Agreement, the Registration Rights
      Agreement and the Warrant are, or when executed and delivered by the
      Company will constitute, the legal, valid and binding obligations of the
      Company, enforceable against the Company in accordance with their
      respective terms.

           (d) Capital Stock.  The capital stock of the Company consists of
      12,000,000 shares of authorized common stock, par value $0.25 per share,
      of which 6,151,911 shares are duly and validly issued, fully paid and
      nonassessable.  The Company has issued options, warrants and convertible
      securities covering an additional 1,415,292 shares of common stock, and
      has reserved for issuance to officers, directors, employees and
      consultants a total of 1,000,000 shares pursuant to stock option plans
      (which number of reserved shares under stock option plans includes
      options issued and which may be issued in the future under such plans).
      Except with respect to such options, warrants and convertible securities
      and antidilution provisions in such options, warrants and convertible
      securities (including options covering such shares so reserved), the
      Company has no agreement or commitments to issue any additional shares of
      common stock.



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           (e) Valid Issuance of Shares.  The Shares to be issued at the
      Closing, and those Shares which may be issued upon exercise of the
      Warrant, when issued, sold and delivered in accordance with the
      provisions of this Agreement and the Warrant, will be duly and validly
      issued, fully paid and nonassessable.  The Shares to be issued upon
      exercise of the Warrant has been duly and validly reserved for issuance.


           (f) No Conflicts.  Except as set forth on Schedule 5.1(f), neither
      the execution, delivery or performance by the Company of this Agreement,
      the Registration Rights Agreement and the Warrant nor the compliance by
      the Company with any of its obligations hereunder or thereunder, nor the
      consummation of any of the transactions contemplated hereby or thereby
      will (i) conflict with the Company's Certificate of Incorporation or
      By-laws or (ii) conflict with or result in a breach of, or constitute a
      default under, or result in the creation or imposition of, any Lien upon
      any of the Company's or its Subsidiaries' property or assets under (A)
      any indenture, mortgage, deed of trust or other instrument or agreement
      to which the Company or its Subsidiaries may be or become bound or to
      which any of the Company's property or assets may be or become subject or
      (B) any applicable law, rule, regulation, judgment, writ, order or decree
      of any Governmental Authority having jurisdiction over the Company's or
      its Subsidiaries' properties or assets.

           (g) No Consents Required.  Except as set forth on Schedule 5.1(g),
      no order, license, consent, authorization or approval of, or exception
      by, or notice to or registration with, any Governmental Authority or any
      other Person, and no filing, recording, publication or registration of
      any kind, other than those which shall have been obtained or given at or
      prior to the Closing, is necessary or advisable in connection with the
      execution, delivery and performance by the Company of this Agreement, the
      Registration Rights Agreement or the Warrant or for the legality,
      validity, binding effect or enforceability thereof.

           (h) Compliance with Laws.  Except as set forth in Schedule 5.1(h),
      neither the Company nor any of its material Subsidiaries is in violation
      of any law, ordinance, rule, regulation, order, policy, guideline or
      other requirement of any Governmental Authority, which violation would
      have a Material Adverse Effect and no such violation has been alleged and
      the Company and the Subsidiaries (i) have filed in a timely manner all
      reports, documents and other materials required to be filed by it with
      any Governmental Authority and the information contained in each of such
      filings is true, correct and complete in all material respects, except
      where failure to make such filings would not have a Material Adverse
      Effect and (ii) have retained all records and documentary evidence
      required to be retained by it pursuant to any law, ordinance, rule,
      regulation, order, policy, guideline or other requirement of any
      Governmental Authority, except where failure to retain such records would
      not have a Material Adverse Effect.

           (i) No Material Adverse Change.  Since December 31, 1994, there has
      been no adverse change in the Company's financial condition, business,
      operations or properties which would have a Material Adverse Effect,
      except as disclosed in the Company's Quarterly Report on Form 10-Q for
      its quarter ended March 31, 1995, in this Agreement or in a Schedule
      hereto.

           (j) Litigation and Adverse Facts.  Except as set forth on Schedule
      5.1(j), there is no action, suit, proceeding, investigation or
      administrative proceeding or arbitration by any Governmental Authority or
      other Person (including, without limitation, derivative actions) pending
      or known by the Company to be threatened with respect to the Company or
      any of its Subsidiaries or assets of any of the foregoing or any of the
      transactions contemplated hereby as to which there is a reasonable
      likelihood of a Material Adverse Effect.

           (k) Exemption From Federal and State Securities Laws.  Based upon
      the representations of the Investor, the offer, sale and issuance of the
      Shares to be issued at the Closing and the Warrant are exempt from the
      registration requirements of the Securities Act of 1933, as amended (the
      "Securities Act"), by virtue of Section 4(2) thereof, are exempt from
      the qualification provisions of the state securities laws of the State of
      Illinois (the "Blue Sky Laws") by virtue of sections 4C, 4G and 4Q
      thereof, and assuming 

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      no change in the Securities Act or Blue Sky Laws between the
      date hereof and the date of exercise of the Warrants, the issuance and
      sale of those Shares which may be issued upon exercise of the Warrant,
      shall also be exempt from the Securities Act and such Blue Sky Laws under
      such sections.

           (l) Absence of Default on Material Contracts.  Neither the Company
      nor its Subsidiaries is in material default under any material contract
      or contracts which in the aggregate would have a Material Adverse Effect.

           (m) Broker's Fees.  No agent, broker, investment banker, Person, or
      firm acting on behalf of the Company is or will be entitled to any
      broker's or finder's fee or any other similar commission or similar fee,
      directly or indirectly, from any of the parties hereto in connection with
      any of the transactions contemplated herein; provided, however, that the
      Company may issue options under the Company's existing stock option plan
      to consultants for their assistance in connection with obtaining the
      rights under the License Agreement and the Supply Agreement.

           (n) Registration Rights.  Except as set forth on Schedule 5.1(n),
      the Company has not granted or agreed to grant any registration rights,
      including piggyback rights, to any Person other than to Investor.

      5.2  Representations and Warranties of The Investor.  The Investor
represents and warrants that on the date hereof and at Closing:

           (a) Power, Authority and Authorization.  Investor has full power and
      authority to enter into this Agreement, the Registration Rights
      Agreement, to purchase and acquire the Securities, and to perform all of
      its obligations hereunder.  All corporate action on the part of the
      Investor, its officers, directors and stockholders necessary for the
      authorization, execution and delivery of this Agreement and the
      Registration Rights Agreement and the performance of all obligations of
      the Investor hereunder and thereunder, have been taken, and this
      Agreement constitutes, and at Closing the Registration Rights Agreement
      will constitute, valid and legally binding obligations, enforceable in
      accordance with their terms.

           (b) Purchase Entirely for Own Account.  This Agreement is made with
      Investor in reliance upon the Investor's representation to the Company,
      which by the Investor's execution of this Agreement the Investor hereby
      confirms, that the Securities will be acquired for investment for the
      Investor's own account, not as a nominee or agent, and not with a view to
      the resale or distribution of any part thereof, and that the Investor has
      no present intention of selling, granting any participation in, or
      otherwise distributing the same.  By executing this Agreement, Investor
      further represents that Investor does not have any contract, undertaking,
      agreement or arrangement with any person to sell, transfer or grant
      participations to such person or to any third person, with respect to any
      of the Securities; provided, however that Investor may transfer the
      Securities, or any part thereof, subject to the provisions of this
      Agreement, to any wholly-owned subsidiary, and such transfer shall not be
      deemed to be a distribution by Investor, or a violation of its
      representations set forth herein.

           (c) Disclosure of Information.  Investor believes it received all
      the information it considers necessary or appropriate for deciding
      whether to acquire the Securities.  Investor further represents that it
      has had an opportunity to ask questions and receive answers from the
      Company regarding the terms and conditions of the acquisition by it of
      the Securities.


           (d) Investment Experience.  Investor can bear the economic risk of
      its investment in the Company and has such knowledge and experience in
      financial or business matters that it is capable of evaluating the merits
      and risks of the investment in the Securities.  Investor also represents
      it has not been organized for the purpose of acquiring the Securities.

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   10

           (e) Accredited Investor.  Investor is an "accredited investor"
      within the meaning of SEC Rule 501 of Regulation D, as presently in
      effect.

           (f) Restricted Securities.  Investor understands that the Securities
      are characterized as "restricted securities" under the Federal securities
      laws inasmuch as they are being acquired from the Company in a
      transaction not involving a public offering and that under such laws and
      applicable regulations such securities may be resold without registration
      under the Securities Act of 1933, as amended (the "Act"), only in certain
      limited circumstances.  In this connection, Investor represents that it
      is familiar with SEC Rule 144, as presently in effect, and understands
      the resale limitations imposed thereby and by the Act.

           (g) Further Limitations on Disposition.  Without in any way limiting
      the representations set forth above, Investor further agrees not to make
      any transfer of all or any portion of the Shares (including any transfer
      to any wholly-owned subsidiary) unless and until the transferee has
      agreed in writing for the benefit of the Company to be bound by the
      provisions of this Agreement applicable to such Shares, and any
      applicable agreement to which Investor is a party, including, without
      limitation, the Registration Rights Agreement and except with respect to
      any transfer other than to a wholly-owned subsidiary of Investor:

                 (i) There is then in effect a Registration Statement under the
            Act covering such proposed disposition and such disposition is made
            in accordance with such Registration Statement; or

                 (ii) A.  Investor shall have notified the Company of the
            proposed disposition and shall have furnished the Company with a
            detailed statement of the circumstances surrounding the proposed
            disposition, and B. if reasonably requested by the Company,
            Investor shall have furnished the Company with an opinion of
            counsel, reasonably satisfactory to the Company, that such
            disposition will not require registration of such shares under the
            Act.

           (h) Legends.  The certificates evidencing the Shares to be issued at
      Closing and the Shares issuable upon exercise of the Warrant may bear one
      or all of the following legends:

                 (i) "The securities represented hereby have not been
            registered under the Securities Act of 1933, as amended.  They may
            not be sold, offered for sale, pledged, hypothecated or transferred
            in the absence of a registration statement in effect with respect
            to the securities under such Act or an opinion of counsel
            satisfactory to the Company that such registration is not required
            or unless sold pursuant to Rule 144 of such Act."

                 (ii) Any legend which, in the opinion of counsel for the
            Company, is required or appropriate under any state or Federal
            securities laws, rules or regulations.

           (i) Broker's Fees.  No agent, broker, investment banker, Person, or
      firm acting on behalf of the Investor is or will be entitled to any
      broker's or finder's fee or any other similar commission or similar fee,
      directly or indirectly, from any of the parties hereto in connection with
      any of the transactions contemplated herein.

                                  ARTICLE 6

                                  COVENANTS

     6.1 Maintain Exchange Act Registration and Listing.  At all times when the
Investor is holding Shares which it received under this Agreement, the Warrant
or Shares it received upon exercise of the Warrant, the 

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Company shall maintain its registration of such Shares under the
Securities Exchange Act of 1934 (the "Exchange Act"), shall make all filings
required under the Exchange Act and shall use its best efforts to have the
Shares continue to be listed on the NASDAQ national market list, or on some
other comparable exchange.  The Company shall not voluntarily withdraw its
Shares from registration under the Exchange Act or withdraw the Shares from such
listing.

     6.2 Perfect Securities Act and Blue Sky Exemptions.  The Company will make
all filings required under the Securities Act and the Blue Sky Laws, if any, to
obtain, secure or perfect applicable exemptions for the issuance of the Shares
to be issued at Closing hereunder, the Warrant and the Shares to be issued upon
exercise of the Warrant.

     6.3 Limitation on Other Registration Rights.  The Company will not grant to
any Person any registration rights, the effect of which is to restrict,
prohibit, limit or make subordinate the registration rights granted to the
Investor under the Registration Rights Agreement, except pursuant to the grant
of rights to Persons which rights are pari passu with the rights of the
Investor, based upon either the total number of shares of Common Stock owned
(including those subject to exercisable warrants or convertible securities) or
the number of shares of Common Stock proposed to be sold by each such party
holding registration rights.


                                  ARTICLE 7

                                 MISCELLANEOUS

     7.1 Assignments.  The Investor shall not assign this Agreement, or any of
its rights hereunder, other than to a party to whom it could assign the Shares
directly under Section 5.2(g).  Upon any permitted assignment of this
Agreement, the Investor and the assignee shall satisfy the requirements of
Section 5.2(g), as though such assignment were a direct assignment of the
Shares.  The assignment of this Agreement shall not release the Investor from
its obligaitons hereunder.

     7.2 Notices.  All notices and other communications hereunder shall be in
writing and shall be deemed given at the time it is received if delivered
personally or by facsimile transmission, mailed by registered or certified mail
(return receipt requested, postage prepaid) or sent by overnight courier
service to the parties at the following addresses (or at such other address for
a party as shall be specified by like notice):

     If to the Company:

     Unimed Pharmaceuticals, Inc.
     2150 East Lake Cook Road
     Buffalo Grove, Illinois  60089-1862
     U.S.A.
     Attention:  Stephen M. Simes, President
     Telecopier No.:  (708) 541-2533

     If to the Investor:

     Laboratoires Besins Iscovesco, S.A.
     5, Rue du Bourg l'Abbe
     75003 Paris
     France
     Attention:  Antoine Besins
     Telecopier No.:  33,1,42,77,14,62

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     with a copy to:

     Besins Iscovesco U.S. Inc.
     620 Herndon Parkway
     Suite 200
     Herndon, Virginia  22073-3840
     Attention:  Jay Bua
     Telecopier No.:  (703) 478-0959

     7.3 Execution in Counterparts.  This Agreement may be executed in
counterparts and by different parties hereto in separate counterparts, each of
which when so executed shall be deemed to be an original and all of which taken
together shall constitute one and the same agreement.

     7.4 Headings.  The Article, Section and subsection headings are inserted
for convenience only and shall not be deemed to constitute part of this
Agreement or to affect the construction hereof.

     7.5 Exhibit and Schedule References.  Any item or matter disclosed in one
Section, Exhibit or Schedule to this Agreement shall be deemed disclosed in any
other Section, Exhibit or Schedule where such disclosure is relevant, even if
there is no express cross-reference, provided that the relevance of the
disclosure is reasonably apparent.  Disclosure of items that may or may not be
required to be disclosed by this Agreement does not mean that such items are
material or create a standard of materiality.

     7.6 Publicity.  If either party wishes to make a public disclosure
concerning this Agreement and such disclosure mentions the other party by name
or description, such other party will be provided with an advance copy of the
disclosure and will have three (3) business days within which to approve or
disapprove such use of its name or description.  Approval shall not be
unreasonably withheld by either party.  Absent approval, no public disclosure
shall use the name of or otherwise describe such party except to the extent
required by law.

     7.7 Binding Effect; Governing Law.  This Agreement shall be binding upon
and inure to the benefit of the Company and the Investor and their respective
successors and assigns.  This Agreement shall be governed by, and construed in
accordance with, the laws of the State of Illinois, without giving effect to
its conflicts of laws principles.

     7.8 Severability.  The invalidity of any provision of this Agreement or
portion of a provision shall not affect the validity of any other portion of
this Agreement or the remaining portion of the applicable provision.

     7.9 Submission to Jurisdiction.  The Company and the Investor hereby
irrevocably submit to the jurisdiction and exclusive venue of any state or
Federal court located in the State of Illinois over any action or proceeding to
enforce or defend any right under this Agreement, the Registration Rights
Agreement and the Warrant, or under any amendment, instrument, document, or
agreement delivered, or that may in the future be delivered, in connection
herewith or therewith, and the Company and the Investor hereby irrevocably
agree that all claims in respect of any such action or proceeding may be heard
and determined in such state or Federal court.  The Company and the Investor
hereby irrevocably waive, to the fullest extent they may effectively do so, the
defense of an inconvenient forum to the maintenance of any such action or
proceeding.  The Company and the Investor agree that a final judgment in any
such action or proceeding shall be conclusive and may be enforced in other
jurisdictions by suit on the judgment or in any other manner provided by law.
The Company and the Investor agree not to institute any legal action or
proceeding against the Company, the Investor or any of their directors,
officers, employees, agents or properties, arising out of or relating to this
agreement or any of the documents referred to above, in any court other than
one hereinabove specified in this Section 7.9.  Nothing in this Section 7.9
shall affect the right of the Company or the Investor to serve legal process in
any other manner permitted by law, or the right of any the Company or the
Investor to bring any action or proceeding against the property of the Company
or the Investor in the courts of any other jurisdictions.



                                      9
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     IN WITNESS WHEREOF, the parties have executed this Agreement, or caused
this Agreement to be executed by their respective officers thereunto duly
authorized, as the case may be, as of the date first above written.

                                          THE COMPANY:
 
                                          UNIMED PHARMACEUTICALS, INC.

                                          By:________________________________

                                          Name and Title:____________________
     
                                          INVESTOR:
     
                                          LABORATOIRES BESINS ISCOVESCO, S.A.

                                          By:_________________________________

                                          Name and Title:_____________________
 


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                                   SCHEDULES



              
Schedule 5.1(b)  Exceptions to due organization, qualification of Subsidiaries

Schedule 5.1(f)  Conflicts with corporate documents, loans, etc. resulting from
                 this Agreement

Schedule 5.1(g)  Consents required

Schedule 5.1(h)  Violations of law, failure to file reports, failure to retain
                 required records.

Schedule 5.1(l)  Defaults under contracts.

Schedule 5.1(n)  Registration rights granted to other parties





   15




                                Schedule 5.1(b)
         Exceptions to due organization, qualification of Subsidiaries


                                      None




















                                      12
   16




                                Schedule 5.1(f)
 Conflicts with corporate documents, loans, etc. resulting from this Agreement


                                      None

















                                      13
   17




                                Schedule 5.1(g)
                               Consents required

                                      None


















                                      14

   18




                                Schedule 5.1(h)
Violations of law, failure to file reports, failure to retain required records.

                                      None















                                      15
   19
                 



                                Schedule 5.1(l)
                           Defaults under contracts.

                                     None




















                                      16
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                                Schedule 5.1(n)
                  Registration rights granted to other parties

The Company has granted registration rights to John Kapoor and The John N.
Kapoor Trust with respect to the shares of common stock, warrants and options
held by them.

The Company has granted registration rights to Life Sciences Corporation with
respect to its warrant for 50,000 shares.





















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