<ARTICLE>            5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FORM THE
FINANCIAL STATEMENTS FOR REPLIGEN CORPORATION AND IS QUALIFIED IN ITS ENTIRETY
BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<CIK>            0000730272
<NAME>           REPLIGEN CORPORATION
<MULTIPLIER>     1
       
                             
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          MAR-31-1995
<PERIOD-START>                             APR-01-1994
<PERIOD-END>                               MAR-31-1995
<CASH>                                      13,821,387
<SECURITIES>                                 1,480,712
<RECEIVABLES>                                1,986,902
<ALLOWANCES>                                 (300,000)
<INVENTORY>                                  1,213,379
<CURRENT-ASSETS>                            24,823,938
<PP&E>                                      20,296,538
<DEPRECIATION>                            (15,312,326)
<TOTAL-ASSETS>                              31,329,953
<CURRENT-LIABILITIES>                       15,753,569
<BONDS>                                              0
<COMMON>                                       153,570
<PREFERRED-MANDATORY>                                0
<PREFERRED>                                          0
<OTHER-SE>                                  15,422,814
<TOTAL-LIABILITY-AND-EQUITY>                31,329,953
<SALES>                                      3,884,642
<TOTAL-REVENUES>                            16,942,315
<CGS>                                        1,535,026
<TOTAL-COSTS>                               32,546,919
<OTHER-EXPENSES>                            16,345,713
<LOSS-PROVISION>                               440,031
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                           (31,950,317)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                       (31,950,317)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                              (31,950,317)
<EPS-PRIMARY>                                   (2.08)
<EPS-DILUTED>                                   (2.08)