SECURITIES AND EXCHANGE COMMISSION
                          WASHINGTON, D.C. 20549





                                 FORM 8-K




                              CURRENT REPORT
                  PURSUANT TO SECTION 13 OR 15(D) OF THE
                      SECURITIES EXCHANGE ACT OF 1934


Date  of  Report  (Date  of earliest event reported)    FEBRUARY 23, 1996


             EMISPHERE         TECHNOLOGIES,         INC.
(Exact Name of Registrant as Specified in Charter)


       DELAWARE                           1-10615             13-3306985
(State or Other Jurisdiction            (Commission         (IRS Employer
     of Incorporation)                  File Number)      Identification No.)



  15 SKYLINE DRIVE, HAWTHORNE, NEW YORK                    10532
(Address of Principal Executive Offices)                  (Zip Code)



Registrant's telephone number, including  area  code:        (914) 347-2220




                          NOT       APPLICABLE



   (Former Name or Former Address, if Changed Since Last Report)



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ITEM 5.  OTHER EVENTS

     (a)  ADOPTION  OF  RIGHTS PLAN.  On February 23, 1996,  the  Board  of
Directors  of  Emisphere Technologies,  Inc.  (the  "Company")  declared  a
dividend of one  preferred  share  purchase  right  (a  "Right")  for  each
outstanding  share  of  common stock, par value $.01 per share (the "Common
Shares"), of the Company.   The  dividend is payable on March 15, 1996 (the
"Record Date") to the stockholders  of  record  at the close of business on
that date.  Each Right entitles the registered holder  to purchase from the
Company  one  one-hundredth  of  a  share of Series A Junior  Participating
Cumulative  Preferred  Stock, par value  $.01  per  share  (the  "Preferred
Shares"), of the Company  at  a  price  of  $80  per one one-hundredth of a
Preferred  Share  (the  "Purchase  Price"),  subject  to  adjustment.   The
description  and  terms of the Rights are set forth in a  Rights  Agreement
(the "Rights Agreement") between the Company and Continental Stock Transfer
& Trust Company, as Rights Agent (the "Rights Agent").

     Until  the earlier  to  occur  of  (i)  10  days  following  a  public
announcement that a person or group of affiliated or associated persons (an
"Acquiring Person")  have  acquired  beneficial ownership of 20% or more of
the outstanding Common Shares or (ii)  10 business days (or such later date
as may be determined by action of the Board of Directors prior to such time
as any person or group of affiliated persons  becomes  an Acquiring Person)
following the commencement of, or announcement of an intention  to  make, a
tender  offer  or exchange offer the consummation of which would result  in
the beneficial ownership  by  a  person  or  group  of  20%  or more of the
outstanding  Common  Shares  (the  earlier  of such dates being called  the
"Distribution Date"), the Rights will be evidenced,  with respect to any of
the Common Share certificates outstanding as of the Record  Date,  by  such
Common  Share  certificate  with  a copy of this Summary of Rights attached
thereto.

     The Rights Agreement provides  that,  until  the Distribution Date (or
earlier  redemption  or  expiration  of  the Rights), the  Rights  will  be
transferred with and only with the Common  Shares.   Until the Distribution
Date (or earlier redemption or expiration of the Rights),  new Common Share
certificates issued after the Record Date upon transfer or new  issuance of
Common Shares will contain a notation incorporating the Rights Agreement by
reference.    Until   the  Distribution  Date  (or  earlier  redemption  or
expiration of the Rights),  the  surrender for transfer of any certificates
for Common Shares outstanding as of  the  Record  Date,  even  without such
notation  or a copy of this Summary of Rights being attached thereto,  will
also constitute  the  transfer  of  the  Rights  associated with the Common
Shares represented by such certificate.  As soon as  practicable  following
the Distribution Date, separate certificates evidencing the Rights  ("Right
Certificates") will be mailed to holders of record of the Common Shares  as
of  the  close of business on the Distribution Date and such separate Right
Certificates alone will evidence the Rights.

     The Rights  are  not  exercisable  until  the  Distribution Date.  The
Rights  will  expire  on  February 23, 2006 (the "Final Expiration  Date"),
unless the Final Expiration  Date  is  extended  or  unless  the Rights are
earlier  redeemed  or exchanged by the Company, in each case, as  described
below.

     The Purchase Price  payable,  and  the  number  of Preferred Shares or
other  securities  or  property issuable, upon exercise of  the  Right  are
subject to adjustment from  time  to  time  to  prevent dilution (i) in the
event   of   a  stock  dividend  on,  or  a  subdivision,  combination   or
reclassification  of,  the Preferred Shares, (ii) upon the grant to holders
of the Preferred Shares  of  certain rights or warrants to subscribe for or
purchase Preferred Shares with  a  conversion  price  less  than  the then-
current market price of the Preferred Shares or (iii) upon the distribution
to  holders of the Preferred Shares of evidences of indebtedness or  assets
(excluding regular periodic cash dividends paid out of earnings or retained
earnings  or  dividends  payable  in  Preferred  Shares) or of subscription
rights or warrants (other than those referred to above).

     The number of outstanding Rights and the number  of one one-hundredths
of a Preferred Share issuable upon exercise of each Right  are also subject
to adjustment in the event of a stock split of the Common Shares or a stock
dividend  on  the  Common  Shares payable

                                -3-



in Common Shares or subdivisions, consolidations or combinations  of the 
Common Shares occurring, in any such case, prior to the Distribution Date.

     Preferred Shares purchasable  upon  exercise of the Rights will not be
redeemable.   Each  Preferred  Share  will  be   entitled   to   a  minimum
preferential  quarterly  dividend  payment  of  $1  per  share  but will be
entitled  to  an aggregate dividend of 100 times the dividend declared  per
Common Share.   In  the  event of liquidation, the holders of the Preferred
Shares will be entitled to  a  minimum  preferential liquidation payment of
$100 per share but will be entitled to an  aggregate  payment  of 100 times
the  payment  made  per  Common Share.  Each Preferred Share will have  100
votes, voting together with  the  Common  Shares.  Finally, in the event of
any merger, consolidation or other transaction  in  which Common Shares are
exchanged, each Preferred Share will be entitled to receive  100  times the
amount  received per Common Share.  These rights are protected by customary
antidilution provisions.

     Because  of  the nature of the Preferred Shares' dividend, liquidation
and voting rights,  the  value  of  the  one  one-hundredth  interest  in a
Preferred  Share purchasable upon exercise of each Right should approximate
the value of one Common Share.

     In the  event  that  the  Company  is  acquired  in  a merger or other
business combination transaction or 50% or more of its consolidated  assets
or  earning  power are sold after a person or group has become an Acquiring
Person, proper  provision  will be made so that each holder of a Right will
thereafter have the right to receive, upon the exercise thereof at the then
current exercise price of the  Right, that number of shares of common stock
of the acquiring company which at  the time of such transaction will have a
market value of two times the exercise  price  of  the Right.  In the event
that  any person or group of affiliated or associated  persons  becomes  an
Acquiring  Person,  proper provision shall be made so that each holder of a
Right, other than Rights  beneficially owned by the Acquiring Person (which
will thereafter be void), will  thereafter  have  the right to receive upon
exercise such number of one one-hundredths of a Preferred  Share  as  shall
equal  the  result  obtained  by  (x) multiplying the then current Purchase
Price by the number of one one-hundredths  of a Preferred Share for which a
Right is then exercisable and dividing that  product by (y) 50% of the then
current per share market price of the Company's Common Shares.

     At any time after any person or group becomes  an Acquiring Person and
prior  to the acquisition by such person or group of 50%  or  more  of  the
outstanding  Common  Shares,  the  Board  of  Directors  of the Company may
exchange the Rights (other than Rights owned by such person  or group which
will  have become void), in whole or in part, for consideration  consisting
of one-half  the  securities  of the Company that would be issuable at such
time upon exercise of one Right.

     With certain exceptions, no  adjustment  in the Purchase Price will be
required until cumulative adjustments require an  adjustment of at least 1%
in  such  Purchase Price.  No fractional Preferred Shares  will  be  issued
(other than  fractions which are integral multiples of one one-hundredth of
a Preferred Share,  which may, at the election of the Company, be evidenced
by depositary receipts)  and in lieu thereof, an adjustment in cash will be
made based on the market price  of the Preferred Shares on the last trading
day prior to the date of exercise.

     At any time prior to the tenth  day  following  the  acquisition  by a
person or group of affiliated or associated persons of beneficial ownership
of 20% or more of the outstanding Common Shares, the Board of Directors  of
the  Company may redeem the Rights in whole, but not in part, at a price of
$.01 per  Right  (the "Redemption Price"); PROVIDED, HOWEVER, that, for the
120-day period after  any  date  of  a  change  (resulting  from a proxy or
consent  solicitation)  in  a  majority  of the Board of Directors  of  the
Company in office at the commencement of such  solicitation, the Rights may
only be redeemed if (A) there are directors then  in  office  who  were  in
office  at  the  commencement  of  such  solicitation  and (B) the Board of
Directors  of  the  Company,  with  the concurrence of a majority  of  such
directors then in office, determines  that  such  redemption  is,  in their
judgment,  in the best interests of the Company and its stockholders.   The
Redemption 
                                -4-



of  the  Rights may be made effective at such time on such basis
with such conditions  as  the Board of Directors in its sole discretion may
establish.  Immediately upon  any  redemption  of  the Rights, the right to
exercise the Rights will terminate and the only right  of  the  holders  of
Rights will be to receive the Redemption Price.

     The  terms  of  the Rights may be amended by the Board of Directors of
the Company without the  consent  of the holders of the Rights, except that
from and after a Distribution Date  no  such amendment may adversely affect
the interests of the holders of the Rights.

     Until a Right is exercised, the holder  thereof, as such, will have no
rights as a stockholder of the Company, including,  without limitation, the
right to vote or to receive dividends.
     This summary description of the Rights does not purport to be complete
and  is  qualified  in its entirety by reference to the  Rights  Agreement,
which is hereby incorporated herein by reference.

     As of February 23,  1996,  there were 8,370,512 shares of Common Stock
outstanding (as well as a further  2,815,389  shares  reserved for issuance
upon  exercise  of outstanding stock options).  Each outstanding  share  of
Common Stock at the  close  of business on the Record Date will receive one
Right.  As long as the Rights are attached to the Common Stock, the Company
will issue one Right with each  new  share of Common Stock so that all such
shares will have attached rights.

     The Rights have certain anti-takeover  effects.  The Rights will cause
substantial  dilution to a person or group that  attempts  to  acquire  the
Company without  conditioning  the  offer on the Rights being redeemed or a
substantial number of Rights being acquired.   However,  the  Rights should
not  interfere  with  any  tender  offer  or merger approved by the Company
(other than with an Acquiring Person) because  the  Rights  do  not  become
exercisable  in the event of an acquisition exempted by the Company's Board
of Directors.

     Attached  hereto as Exhibit 1 and incorporated herein by reference are
copies of the Rights  Agreement  and  the  exhibits  thereto,  as  follows:
Exhibit   A   --  Certificate  of  Designations  of  the  Series  A  Junior
Participating Cumulative  Preferred  Stock;  Exhibit  B  --  Form of Rights
Certificate;  and  Exhibit  C  --  Summary  of Rights to Purchase Preferred
Shares.   THE  FOREGOING  DESCRIPTION OF THE RIGHTS  IS  QUALIFIED  IN  ITS
ENTIRETY BY REFERENCE TO THE RIGHTS AGREEMENT AND SUCH EXHIBITS THERETO.



ITEM  7.   FINANCIAL  STATEMENTS,   PRO  FORMA  Financial  Information  and
Exhibits.

     (C)  EXHIBITS.

     4.   Rights Agreement, dated as  of  February 23, 1996, by and between
          Emisphere Technologies, Inc. and  Continental  Stock  Transfer  &
          Trust  Company,  as  Rights  Agent,  which  includes  the form of
          Certificate of Designations setting forth the terms of the Series
          A  Junior  Participating  Cumulative  Preferred Stock, par  value
          $0.01 per share, as Exhibit A, the form  of  Right Certificate as
          Exhibit B and the Summary of Rights to Purchase  Preferred Shares
          as Exhibit C.

     99.  Press Release issued March 5, 1996.



                                -5-



                            SIGNATURES


     Pursuant to the requirements of the Securities Exchange  Act  of 1934,
the  registrant  has duly caused this report to be signed on its behalf  by
the undersigned hereunto duly authorized.



                                   EMISPHERE TECHNOLOGIES, INC.



Date:  March 5, 1996     By:  /S/ MICHAEL M. GOLDBERG
                                        Michael M. Goldberg, M.D.
                                        Chairman and Chief
                                        Executive Officer




                                -6-


                           EXHIBIT INDEX


EXHIBIT                  DESCRIPTION OF THE EXHIBIT                        PAGE

4.        Rights Agreement,  dated  as of February 23, 1996, by and between
          Emisphere Technologies, Inc.  and  Continental  Stock  Transfer &
          Trust Company, as Rights Agent.

99.       Press Release issued March 5, 1996.



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