Exhibit 16.01 [Arthur Andersen LLP Letterhead] Office of the Chief Accountant Securities and Exchange Commission 450 Fifth Street, N.W. Washington, D.C. 20549 May 17, 2002 Dear Sir/Madam: We have read Item 4 included in the Form 8-K dated May 17, 2002 of Quintiles Transnational Corp. to be filed with the Securities and Exchange Commission and are in agreement with the statements contained therein. Very truly yours, /s/ Arthur Andersen LLP Copy to: Mr. James L. Bierman, CFO, Quintiles Transnational Corp.