EXHIBIT 32.2

              CERTIFICATION OF CHIEF FINANCIAL OFFICER PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

     In connection with the Annual Report of ProxyMed, Inc. (the "Company") on
Form 10-K for the period ending December 31, 2005 as filed with the Securities
and Exchange Commission on the date hereof (the "Report"), I, Douglas J. O'Dowd,
certify, pursuant to 18 U.S.C. ss.1350, as adopted pursuant to ss.906 of the
Sarbanes-Oxley Act of 2002, that:

     (1) The Report fully complies with the requirements of section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

     (2) The information contained in the Report fairly presents, in all
material respects, the financial condition and result of operations of the
Company.

/s/ DOUGLAS J. O'DOWD
- --------------------------------



Douglas J. O'Dowd
Chief Financial Officer
March 14, 2006

A signed original of this written statement required by Section 906 has been
provided to ProxyMed, Inc. and will be retained by ProxyMed, Inc. and furnished
to the Securities and Exchange Commission or its staff upon request.