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    As filed with the Securities and Exchange Commission on April 29, 1997
                                                  REGISTRATION NO. 333-_________
================================================================================
                     SECURITIES AND EXCHANGE COMMISSION
                           Washington, D.C.  20549

                            --------------------

                                  FORM S-8

                        REGISTRATION STATEMENT UNDER
                         THE SECURITIES ACT OF 1933

                            --------------------

                            MEDAPHIS CORPORATION
           (Exact name of registrant as specified in its charter)


                 DELAWARE                                 58-1651222
      (State or other jurisdiction of                   (I.R.S. Employer
      incorporation or organization)                   Identification No.)


                           2700 CUMBERLAND PARKWAY
                                  SUITE 300
                           ATLANTA, GEORGIA 30339
 (Address, including zip code, of registrant's principal executive offices)

            MEDAPHIS CORPORATION NON-QUALIFIED STOCK OPTION PLAN
                         FOR NON-EXECUTIVE EMPLOYEES
                            (Full title of plan)

                              DAVID E. MCDOWELL
                    CHAIRMAN AND CHIEF EXECUTIVE OFFICER
                           2700 CUMBERLAND PARKWAY
                                  SUITE 300
                           ATLANTA, GEORGIA 30339
                               (770) 444-5300
              (Name, address, including zip code, and telephone
              number, including area code, of agent for service)

                                 WITH A COPY TO:

                          WILLIAM R. SPALDING, ESQ.
                               KING & SPALDING
                             191 PEACHTREE STREET
                         ATLANTA, GEORGIA 30303-1763
                                (404) 572-4600



                       CALCULATION OF REGISTRATION FEE



=========================================================================================================================
                                                              Proposed Maximum      Proposed Maximum 
                                                Amount to    Offering Price Per    Aggregate Offering      Amount of 
Title of Securities to be Registered          be Registered      Share(1)             Price(1)          Registration Fee
- -------------------------------------------------------------------------------------------------------------------------
                                                                                              
Common Stock, par value $.01 per share . . .   1,025,000        $4.6875              $4,804,687.50        $1,455.97  
- -------------------------------------------------------------------------------------------------------------------------
(1)   Estimated solely for the purpose of computing the registration fee pursuant to Rule 457(h) on the basis of the
      high and low prices of Common Stock of Medaphis Corporation on April 22, 1997.

                                                                                          Exhibit Index Located on Page 8
                                                                                                      Page 1 of 29 Pages

=========================================================================================================================

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                                    PART I

             INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

     The document(s) containing the information specified in Part I of Form S-8
will be sent or given to participating employees as specified by Rule 428(b)(1)
of the Securities Act of 1933, as amended (the "Securities Act").  These
documents and the documents incorporated by reference into this Registration
Statement pursuant to Item 3 of Part II of this Registration Statement, taken
together, constitute a prospectus that meets the requirements of Section 10(a)
of the Securities Act.


                                    PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3.     Incorporation of Certain Documents by Reference.

     The following documents previously filed by the Registrant with the
Securities and Exchange Commission are incorporated by reference in this
Registration Statement:

            (a)    The Registrant's Annual Report on Form 10-K for the fiscal
     year ended December 31, 1996, filed on March 31, 1997;

            (b)    All reports filed by the Registrant pursuant to Section
     13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
     "Exchange Act"), since December 31, 1996; and

            (c)    The description of Medaphis common stock, par value $.01 per
     share ("Common Stock"), contained in the Registration Statement on Form
     8-A/A dated May 22, 1996.

     All documents filed by the Registrant subsequent to the date of this
Registration Statement pursuant to Sections 13(a), 13(c), 14 and 15(d) of the
Exchange Act and prior to the filing of a post-effective amendment which
indicates that all securities offered hereunder have been sold or which
deregisters all securities then remaining unsold shall be deemed to be
incorporated by reference in this Registration Statement and to be a part of
this Registration Statement from the date of filing of such documents.

Item 5.     Interests of Named Experts and Counsel.

     The validity of the issuance of the shares of Common Stock offered hereby
will be passed upon for the Company by King & Spalding, Atlanta, Georgia. 
King & Spalding also advises and represents the Company with respect to
various matters.  The Company will pay King & Spalding's fees and expenses in
connection with this Registration Statement.  William R. Spalding served as an
executive officer of the Company until his election as a partner of King & 
Spalding on April 11, 1997.

Item 6.     Indemnification of Directors and Officers.

     The following summary is qualified in its entirety by reference to the
complete text of the statute, Amended and Restated Certificate of
Incorporation, as amended, Amended and Restated By-Laws and agreement referred
to below.

     The Registrant's Amended and Restated By-Laws provide that each person who
was or is made a party to, is threatened to be made a party to or is otherwise
involved in any action, suit or proceeding, whether civil, criminal,
administrative or investigative, by reason of the fact that he is or was a
director, officer, employee or agent of the Registrant (or is or was serving at
the request of the Registrant as a director, officer, employee or agent of
another entity), will be indemnified and held harmless by the Registrant to the
fullest extent permitted by the Delaware General Corporation Law (the "DGCL") 
as it currently exists or is later amended.

     Under Section 145 of the DGCL, a corporation may indemnify a director, 
officer, employee or agent of the corporation (or other entity if such person
is serving in such capacity at the corporation's request) against expenses
(including attorneys' fees), judgments, fines and amounts paid in settlement
actually and reasonably incurred by him if he acted in good faith and in a
manner he reasonably believed to be in, or not opposed to, the best interests
of the corporation and, with respect to any criminal action or proceeding, had
no reasonable cause to believe his conduct was unlawful.  In the case of an
action brought by or in the right of the corporation, the corporation may
indemnify a director, officer, employee or agent of the corporation (or other
entity if such person is serving in such capacity at the corporation's request)
against expenses (including attorneys' fees) actually and reasonably incurred
by him if he acted in good faith and





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in a manner he reasonably believed to be in, or not opposed to, the best
interests of the corporation, except that no indemnification shall be made in
respect of any claim, issue or matter as to which such person shall have been
adjudged to be liable to the corporation unless a court determines that,
despite the adjudication of liability but in view of all the circumstances of
the case, such person is fairly and reasonably entitled to indemnification for
such expenses as the court shall deem proper.  Expenses (including attorneys'
fees) incurred by an officer or director in defending any civil, criminal,
administrative or investigative action, suit or proceeding may be paid by the
corporation in advance of the final disposition of such action, suit or
proceeding upon receipt of an undertaking by or on behalf of such director or
officer to repay such amount if it shall ultimately be determined that he is
not entitled to be indemnified by the corporation.

     The Registrant's Amended and Restated Certificate of Incorporation, as
amended, provides that a director of the Registrant shall not be personally
liable to the Registrant or its stockholders for monetary damages for breach of
fiduciary duty as a director, except for liability (i) for any breach of the
director's duty of loyalty to the Registrant or its stockholders, (ii) for any
acts or omissions not in good faith or which involve intentional misconduct or
a knowing violation of law, (iii) under Section 174 of the DGCL or (iv) for any 
transaction in which the director derived an improper personal benefit.

     In addition, the Registrant and David E. McDowell are parties to an
agreement pursuant to which the Registrant has agreed to indemnify and hold
harmless Mr. McDowell to the fullest extent permitted by the DGCL as it 
presently exists or to such greater extent as such law may subsequently be 
amended.

     The Registrant maintains directors and officers liability insurance.  Such
policies have a deductible of $500,000 and an annual per occurrence and
aggregate cap on coverage of $50 million.


Item 8.     Exhibits.




Exhibit            Description
- -------            -----------
                
4.1                Amended and Restated Certificate of Incorporation of 
                   Registrant (incorporated by reference to Exhibit 4.1 of 
                   Registrant's Registration Statement on Form S-8, File 
                   No. 333-03213).

4.2                Certificate of Amendment of Amended and Restated Certificate
                   of Incorporation of Registrant (incorporated by reference 
                   to Exhibit 4.4 of Registrant's Registration Statement on 
                   Form S-8, File No. 333-03213).

4.3                Certificate of Amendment of Amended and Restated Certificate
                   of Incorporation of Registrant (incorporated by reference 
                   to Exhibit 3.3 of Registrant's Registration Statement on 
                   Form 8-A/A, filed on May 22, 1996).                         

4.4                Amended and Restated By-Laws of Registrant (incorporated by 
                   reference to Exhibit 3.2 of Registrant's Annual Report on
                   Form 10-K for the year ended December 31, 1992, File 
                   No. 000-19480).

4.5                Form of Warrant (incorporated by reference to Exhibit 4.4 of
                   Registrant's Current Report on Form 8-K filed on February 
                   18, 1997).

4.6                Specimen Common Stock Certificate (incorporated by reference
                   to Exhibit 4.1 of Registrant's Annual Report on Form 10-K
                   for the year ended December 31, 1995).

5.1                Opinion of King & Spalding regarding legality of shares 
                   being registered.

23.1               Consent of Deloitte & Touche LLP.








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23.2               Consent of King & Spalding (contained in the opinion filed 
                   as Exhibit 5.1).

99.1               Medaphis Corporation Non-Qualified Stock Option Plan for 
                   Non-Executive Employees.

99.2               First Amendment to the Medaphis Corporation Non-Qualified 
                   Stock Option Plan for Non-Executive Employees.


Item 9.     Undertakings
            


     The undersigned Registrant hereby undertakes:

     (a)(1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement;

            (i)    To include any prospectus required by Section 10(a)(3) of
     the Securities Act;

           (ii)    To reflect in the prospectus any facts or events arising
     after the effective date of the Registration Statement (or the most recent
     post-effective amendment thereof) which, individually or in the aggregate,
     represent a fundamental change in the information set forth in the
     Registration Statement.  Notwithstanding the foregoing, any increase or
     decrease in volume of securities offered (if the total dollar value of
     securities offered would not exceed that which was registered) and any
     deviation from the low or high and of the estimated maximum offering range
     may be reflected in the form of prospectus filed with the Commission
     pursuant to Rule 424(b) if, in the aggregate, the changes in volume and
     price represent no more than 20 percent change in the maximum aggregate
     offering price set forth in the "Calculation of Registration Fee" table in
     the effective Registration Statement;

          (iii)    To include any material information with respect to the plan
     of distribution not previously disclosed in the Registration Statement or
     any material change to such information in the Registration Statement;

provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed with or furnished to the
Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange 
Act that are incorporated by reference in the Registration Statement.

     (2)    That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new 
registration statement relating to the securities offered therein, and the 
offering of such securities at that time shall be deemed to be the initial
bona fide offering thereof.

     (3)    To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination
of the offering.

     (b)    That, for purposes of determining any liability under the
Securities Act, each filing of the Registrant's annual report pursuant to
Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing
of an employee benefit plan's annual report pursuant to Section 15(d) of the
Exchange Act) that is incorporated by reference in this Registration Statement
shall be deemed to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time shall be
deemed to be the initial bona fide offering thereof.

     (c)    Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the foregoing provisions, or otherwise, the
Registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable.  In the event that a claim for
indemnification against such labilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the





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Registrant in the successful defense of any action, suit or proceeding) is
asserted by such director, officer or controlling person in connection with the
securities being registered, the Registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent, submit to a court
of appropriate jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and will be governed 
by the final adjudication of such issue.












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                                   SIGNATURES


     Pursuant to the requirements of the Securities Act of 1933, Medaphis
Corporation certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-8 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Atlanta, State of Georgia, on this 29th day of
April, 1997.


                                       MEDAPHIS CORPORATION


                                       By: /s/ Jerome H. Baglien 
                                          ------------------------------------
                                          Jerome H. Baglien
                                          Senior Vice President, Chief
                                          Financial Officer and Assistant
                                          Secretary










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     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.





Signature                              Title                               Date                      
- ---------                              -----                               ----                      
                                                                             
/s/ David E. McDowell                  Chairman, Chief Executive           April 29, 1997
- ----------------------------           Officer and Director                           
David E. McDowell                                                                                        
                                                                                                                             
                                                                                    
/s/ Jerome H. Baglien                  Senior Vice President,              April 29, 1997
- ----------------------------           Chief Financial Officer and                  
Jerome H. Baglien                      Assistant Secretary                          
                                       (principal financial officer     
                                       and acting principal 
                                       accounting officer)                                             
                                                                                    
/s/ Robert C. Bellas, Jr.              Director                            April 29, 1997
- ----------------------------                                                                                                 
Robert C. Bellas, Jr.                                                                                                        
                                                                                                                             
                                                                                                                             
/s/ David R. Holbrooke, M.D.           Director                            April 29, 1997                                    
- ----------------------------                                                        
David R. Holbrooke, M.D.                                                                                                     
                                                                                    
                                                                                                                             
/s/ John C. Pope                       Director                            April 29, 1997                                    
- ----------------------------                                                                                                 
John C. Pope                                                                                                                 
                                                                                                                             
                                                                                                         
/s/ Dennis A. Pryor                    Director                            April 29, 1997 
- ----------------------------                                                        
Dennis A. Pryor






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                                 EXHIBIT INDEX





Exhibit                                         Description                                                          Page
- -------                                         -----------                                                          ----
                                                                                                                        
4.1                Amended and Restated Certificate of Incorporation of Registrant (incorporated by
                   reference to Exhibit 4.1 of Registrant's Registration Statement on Form S-8, File
                   No. 333-03213).                                                                                    --

4.2                Certificate of Amendment of Amended and Restated Certificate of Incorporation
                   of Registrant (incorporated by reference to Exhibit 4.4 of Registrant's Registration
                   Statement on Form S-8, File No. 333-03213).                                                        --

4.3                Certificate of Amendment of Amended and Restated Certificate of Incorporation
                   of Registrant (incorporated by reference to Exhibit 3.3 of Registrant's Registration
                   Statement on Form 8-A/A, filed on May 22, 1996).                                                   --

4.4                Amended and Restated By-Laws of Registrant (incorporated by reference to Exhibit
                   3.2 of Registrant's Annual Report on Form 10-K for the year ended December 31, 1992,               --
                   File No. 000-19480).

4.5                Form of Warrant (incorporated by reference to Exhibit 4.4 of Registrant's Current Report
                   on Form 8-K filed on February 18, 1997).                                                           --

4.6                Specimen Common Stock Certificate (incorporated by reference to Exhibit 4.1 of Registrant's        --        
                   Annual Report on Form 10-K for the year ended December 31, 1995).

5.1                Opinion of King & Spalding regarding legality of shares being registered.                          --

23.1               Consent of Deloitte & Touche LLP.                                                                  --

23.2               Consent of King & Spalding (contained in the opinion filed as Exhibit 5.1).                        --

99.1               Medaphis Corporation Non-Qualified Stock Option Plan for Non-Executive Employees.                  --

99.2               First Amendment to the Medaphis Corporation Non-Qualified Stock Option Plan for                    --
                   Non-Executive Employees.






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