CERTIFICATE OF INCORPORATION of CPF/METPATH INC. FIRST, the name of the Corporation is CPF/MetPath Inc. SECOND, the address of the corporation's registered office in the State of Delaware is 1209 Orange Street, in the City of Wilmington, County of New Castle. The name of the Registered Agent at such address is The Corporation Trust Company. THIRD, the purpose of the corporation is (i) to own and operate medical, clinical, industrial and research laboratories, and (ii) to research, manufacture, design, construct, use, buy, sell, lease, hire and deal in and with articles and property of all kinds, to render services of all kinds, and (iii) generally to engage in any lawful act or activity for which corporations may be organized under the General Corporation Law of Delaware. FOURTH, the total number of shares of all classes of stock which the corporation shall have authority to issue is 1,000 shares which shall be Common Stock, all of which shares shall be without par value, and each with a right to one vote. 1 FIFTH, the name and mailing address of the Incorporator is as follows: Name Mailing Address Raymond C. Marier 2 West Market Street Corning, NY 14830 SIXTH, the names and mailing addresses of the persons who are to serve as directors until the first annual meeting of stockholders of the corporation or until their successors axe elected and qualify, are as follows: Name Mailing Address Raymond C. Marier 2 West Market Street Corning, NY 14830 Richard A. Michaelson One Malcolm Avenue Teterboro, NJ 07608 Douglas M. VanOort 2 West Market Street Corning, NY 14830 SEVENTH, the corporation may indemnify, to the full extent permitted by applicable law, any person who was or is a party, or is threatened to he made a party, to any threatened or pending action, suit or proceeding, whether civil, criminal, administrative, or investigative, by reason of the fact that he or she is or was a director or officer of the corporation, or is or was serving at the request of the corporation, as a director or officer of another corporation, partnership, joint venture, trust or other enterprise. Any indemnification pursuant to the foregoing shall be made by the corporation only as authorized in the specific case upon a determination that indemnification of the director or officer is proper under the circumstances 2 because he or she has met any legally applicable standard of conduct. Such determination may be made (i) be resolution of the Board of Directors adopted in the manner provided in the By-laws of the corporation, or (ii) if a quorum consisting of directors or are not parties to such action, suit or proceeding, is not obtainable, or, even if obtainable, a quorum of disinterested directors so directs, by independent legal counsel in a written opinion, or (iii) by the stockholders. EIGHTH, any action required or permitted to be taken at any annual or special meeting of stockholders of the corporation may be taken without a meeting, without prior notice and without a vote, if a consent in writing, setting forth the actions so taken, shall be signed by the holders of outstanding stock having not less than the minimum number of votes that would be necessary to authorize or take such action at a meeting at which all shares entitled to vote thereon are present and voted. THE UNDERSIGNED, being the sole Incorporator hereinbefore named, for the purpose of forming a corporation pursuant to the General Corporation Law of the State of Delaware, does hereby make this Certificate, declaring and certifying that this is his act and 3 deed and the facts herein stated are true, and accordingly has hereunto set his hand this 14th day of October, 1991. /s/ Raymond C. Marier -------------------------------- Raymond C. Marier 2 West Market Street Corning, NY 14830 STATE OF NEW YORK ) ) s.s.: COUNTY OF STEUBEN ) BE IT REMEMBERED, that on this 14th day of October, 1991, personally came before me, a Notary Public in and for the State of New York and the County of Steuben, Raymond C. Marier, the sole Incorporator named in the foregoing Certificate of Incorporation, known to me personally to be such, and he acknowledged the said Certificate to be his act and deed and that the facts stated therein are truly set forth. GIVEN under my hand and seal of office the day and year aforesaid. /s/ Barbara E. Wellington ------------------------------------- Barbara E. Wellington 4 CERTIFICATE OF AMENDMENT OF CERTIFICATE OF INCORPORATION OF CPF/METPATH INC. The undersigned directors of CPF/MetPath Inc., a Delaware Corporation (the "Corporation"), for purposes of amending the Certificate of Incorporation of the Corporation filed October 16, 1991, hereby certify as follows: FIRST, the Certificate of Incorporation is hereby amended such that name of the Corporation is changed to CPF/Corning Inc. SECOND, the Corporation has not received any payment for any of its stock. THIRD, the amendment herein has been duly adopted in accordance with the provisions of Section 241 of the General Corporation Law of the State of Delaware to be effective as 5 provided therein, and this Certificate is duly executed by a majority of the directors of the Corporation in accordance with Section 103(a)(2)(ii) of said General Corporation Law. /s/ Raymond C. Marier ---------------------- Raymond C. Marier 2 West Market Street Corning, NY 14830 [Director] /s/ Douglas M. VanOort ---------------------- Douglas M. VanOort 2 West Market Street Corning, NY 14830 [Director] STATE OF NEW YORK ) ) S.S.: COUNTY OF STEUBEN ) Be it remembered that on this 4th day of November, 1991 personally came before me a Notary Public in and for the State of New York and County of Steuben, Raymond C. Marier and Douglas M. VanOort named in the foregoing Certificate of Amendment, known to me personally to be such, and they each acknowledged the said Certificate to be his act and deed and that the facts stated therein are truly set forth. Given under my hand and seal of office the day and year aforesaid. /s/ Barbara E. Wellington --------------------------------------------- Barbara E. Wellington Notary Public, State of New York Qualified in Steuben County No. 4914239 My Commission Expires December 14, 1991 CPF a:\Amend. 6 STATE OF DELAWARE BK 1221 PG 0535 SECRETARY OF STATE DIVISION OF CORPORTIONS FILED 10:30 AM 11/26/1991 721330013 - 2276289 CERTIFICATE OF MERGER OF CLINICAL PATHOLOGY FACILITY, INC., A PENNSYLVANIA CORPORATION INTO CPF/CORNING INC., A DELAWARE CORPORATION The undersigned corporation DOES HEREBY CERTIFY: FIRST: That the name and state of Incorporation of each of the constituents of the Merger is as follows: NAME STATE OF INCORPORATION Clinical Pathology Facility, Inc. Pennsylvania CPF/Corning Inc. Delaware SECOND: That an Agreement of Merger dated November 11, 1991 between CPF/Corning Inc., a Delaware corporation and Clinical Pathology Facility, Inc., a Pennsylvania corporation ("Clinical"), the constituent corporations of the merger, has been approved, adopted, certified, executed and acknowledged by each of the constituent corporations as follows: In the case of CPF/Corning Inc., in accordance with the requirements of Subsection (c) of Section 252 of the Delaware Corporation Law of the State of Delaware; and in the case of Clinical, in accordance with Section 1924 of the Associations Code of the Commonwealth of Pennsylvania. THIRD: That the name of the surviving corporations of the Merger is hereby changed from CPF/CORNING INC., a Delaware corporation, to CLINICAL PATHOLOGY FACILITY, INC., a Delaware corporation. FOURTH: That the Certificate of Incorporation of CPF/Corning Inc., a Delaware corporation, shall be the Certificate of Incorporation of the surviving corporation except that Article First of the Certificate of Incorporation shall be amended to read in full as follows: "FIRST, the name of the Corporation is Clinical Pathology Facility, Inc." FIFTH: That the executed Agreement and Plan of Merger is on file at the principal place of business of the surviving corporation, the address of which is 711 Bingham Street, Pittsburgh, Pennsylvania 15203. 7 SIXTH: That a copy of the executed Agreement and Plan of Merger will be furnished by the surviving corporation on request and without cost to any stockholder of either constituent corporation. SEVENTH: That the authorized capital stock of each foreign [to Delaware] corporation which is a party to the merger is as follows: Shares Par Corporation Class Authorized Value Clinical Pathology Facility, Inc. Common 600,000 $1 per share a Pennsylvania corporation The undersigned officers of the surviving corporation of the merger do sign this Certificate of Merger pursuant to Section 252(c) of the General Corporation Law of the State of Delaware. November 26, 1991 CPF/CORNING INC. [SEAL] By:/s/ Richard A. Michaelson ---------------------------------- Richard A. Michaelson, President ATTEST: /s/ Raymond C. Marier - ---------------------------- Raymond C. Marier, Secretary 8 CERTIFICATE OF MERGER OF MEDICAL MANAGEMENT SYSTEMS, INC. INTO CLINICAL PATHOLOGY FACILITY, INC. Pursuant to Section 252 of the General Corporation Law of the State of Delaware * * * * The undersigned hereby certifies that: 1. The name of and state of incorporation of each of the constituent corporations are as follows: Name State of Incorporation MEDICAL MANAGEMENT SYSTEMS, INC. Pennsylvania CLINICAL PATHOLOGY FACILITY, INC. Delaware 2. An Agreement and Plan of Merger dated as of December 6, 1994 (the "Merger Agreement") between Medical Management Systems, Inc. and Clinical Pathology Facility, Inc. has been approved, adopted, certified, executed and acknowledged by each of the constituent corporations in accordance with the requirements of Section 252(c) of the General Corporation Law of the State of Delaware. 3. The name of the surviving corporation is Clinical Pathology Facility, Inc. 4. The Certificate of Incorporation of Clinical Pathology Facility, Inc. in effect at the effective time of the merger shall be the Certificate of Incorporation of the surviving corporation except that Article 1 of the Certificate of Incorporation of Clinical Pathology Facility, Inc shall be amended as of the effective time of the Merger to read as follows: "The name of the Corporation is MetPath (PA) Inc." 5. The surviving corporation is a corporation of the State of Delaware. 6. The executed Merger Agreement is on file at the principal place of business of the surviving corporation at 711 Bingham Street, Pittsburgh, Pennsylvania 15213. 7. A copy of the Merger Agreement will be furnished by the surviving corporation, on request and without cost, to any stockholder of any constituent corporation. 9 8. The authorized capital stock of the Medical Management Systems, Inc. is 2,000,000 shares of Common Stock, par value $1.00 per share. 9. That the merger shall become effective at 11:59 P.M. on December 31, 1994. IN WITNESS WHEREOF, this Certificate of Merger has been executed on this 6th day of December, 1994. Attest: CLINICAL PATHOLOGY FACILITY, INC. /s/ Leo C. Farrenkopf, Jr By: /s/ James D. Chambers - ------------------------- ------------------------ Leo C. Farrenkopf, Jr. James D. Chambers Secretary Vice President 10 CERTIFICATE OF AMENDMENT OF CERTIFICATE OF INCORPORATION MetPath (PA) Inc. a corporation organized and existing under and by virtue of the General Corporation Law of the state of Delaware, DOES HEREBY CERTIFY: FIRST: By unanimous written consent of the Board of Directors, resolutions were duly adopted setting forth a proposed amendment of Article 1 of the Certificate of Incorporation of said corporation declaring said amendment to be advisable and calling a meeting of the stockholders of said corporation for consideration thereof. The resolution setting forth the proposed amendment is as follows: RESOLVED, that the Board of Directors hereby approves the amendment to Article 1 of the Company's Certificate of Incorporation to read as follows: The name of the corporation (which is hereafter referred to as the "Corporation") is Corning Clinical Laboratories of Pennsylvania Inc. SECOND: That said amendment was approved by the unanimous written consent of the sole stockholder of the Corporation in accordance with Section 228 of the General Corporation Law of the state of Delaware. THIRD: That said amendment was duly adopted in accordance with Section 242 (a)(1) of the Business Corporation Act of the state of Delaware IN WITNESS WHEREOF, said corporation has used this certificate to be signed by Raymond C. Marier, its Vice President, and Leo C. Farrenkopf, Jr., its Secretary this 28th day of December, 1995. BY: /s/ Raymond C. Marier --------------------------- Raymond C. Marier Vice President ATTEST: /s/ Leo C. Farrenkopf, Jr. --------------------------- Leo C. Farrenkopf, Jr. Secretary 11