Exhibit 23.1

                          INDEPENDENT AUDITORS' CONSENT


To the Board of Directors
of Matrixx Initiatives, Inc.

We consent to the incorporation by reference in the following Registration
Statements of Matrixx Initiatives, Inc. and any amendments thereto: (1) No.
333-06199 on Form S-8; (2) No. 333-34019 on Form S-8; (3) No. 333-91679 on Form
S-3; (4) No. 333-30194 on Form S-3; (5) No. 333-98901 on Form S-3; and (6) No.
333-99311 on Form S-8, of our report dated January 24, 2003, relating to the
consolidated balance sheet of Matrixx Initiatives, Inc. as of December 31, 2002
and the related consolidated statements of operations, cash flows and changes in
stockholders' equity for the year ended December 31, 2002, which report appears
or is incorporated by reference in the December 31, 2002 Annual Report on Form
10-K of Matrixx Initiatives, Inc.

                                       /s/ Mayer Hoffman McCann P.C.


Phoenix, Arizona
March 25, 2003