As filed with the Securities and Exchange Commission on April 30, 1998
                                               Registration No. 333-
================================================================================
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                           --------------------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      Under
                           The Securities Act of 1933
                           --------------------------

                                 CONSYGEN, INC.
             (Exact Name of Registrant as Specified in its Charter)

              Texas                                           76-0260145
  (State or Other Jurisdiction of                          (I.R.S. Employer
  Incorporation or Organization)                         Identification Number)

      10201 South 51st Street, Suite 140, Phoenix, AZ 85044, (602) 496-4545
          (Address, Including Zip Code, and Telephone Number, Including
             Area Code, of Registrant's Principal Executive Offices)

                           --------------------------

               ConSyGen, Inc. 1996 Non-Qualified Stock Option Plan
               ---------------------------------------------------
    ConSyGen, Inc. 1997 Amended and Restated Non-Qualified Stock Option Plan
    ------------------------------------------------------------------------
                              (Full title of Plans)

                           --------------------------

                                Ronald I. Bishop
                      President and Chief Executive Officer
                       10201 South 51st Street, Suite 140
                                Phoenix, AZ 85044
                                 (602) 496-4545
                      (Name, Address and Telephone Number,
                   Including Area Code, of Agent for Service)

                                 with a copy to:

                           John G. Nossiff, Jr., Esq.
                         Brown, Rudnick, Freed & Gesmer
                One Financial Center, Boston, Massachusetts 02111
                                 (617) 856-8200

                           --------------------------


                                               CALCULATION OF REGISTRATION FEE
===============================================================================================================================
                                                                  Proposed                Proposed
                                             Amount                Maximum                Maximum               Amount of
       Title of Each Class of                to Be             Offering Price            Aggregate            Registration
    Securities to Be Registered            Registered           Per Share(1)         Offering Price(1)             Fee
- ------------------------------------- --------------------- ---------------------- ----------------------- --------------------
                                                                                                          
Common Stock, $. 003 par value        3,500,000 Shares(2)           $5.98               $20,930,000             $6,342.42
===============================================================================================================================

(1)   Estimated  solely for purposes of  calculating  the  registration  fee pursuant to Rule 457(c) under the Securities Act of
      1933,  on the basis of the average of the high and low  reported  price of the Common  Stock of $5.98 on the Nasdaq  Stock
      Market's SmallCap Market on April 28, 1998.

(2)   The Shares being registered  hereunder  include  2,000,000  shares that may be issued pursuant to the ConSyGen,  Inc. 1997
      Amended and Restated  Non-Qualified  Stock Option Plan and 1,500,000  shares that may be issued  pursuant to the ConSyGen,
      Inc. 1996 Non-Qualified Stock Option Plan. Such presently  indeterminable  number of additional shares of Common Stock are
      also  registered  hereunder as may be issued in the event of a merger,  consolidation,  reorganization,  recapitalization,
      stock dividend, stock split or other similar change in Common Stock.
===============================================================================================================================


                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3.  Incorporation of Documents by Reference.
- -------  ----------------------------------------

         The following  documents are hereby incorporated by reference into this
Registration Statement:

         (a)      The  Registrant's  Annual  Report on Form 10-K for the  fiscal
                  year ended May 31,  1997 filed  pursuant  to Section  13(a) or
                  15(d) of the Securities  Exchange Act of 1934, as amended (the
                  "Exchange Act");

         (b)      The  Registrant's  quarterly  reports  on  Form  10-Q  for the
                  quarters ended August 31, 1997, November 30, 1997 and February
                  28,  1998  filed  pursuant  to  Section  13(a) or 15(d) of the
                  Exchange Act; and

         (c)      The description of the Registrant's  Common Stock contained in
                  the  Registrant's  Registration  Statement  on  Form  8-A,  as
                  amended by Amendment No. 1 thereto (Registration No. 0-17598),
                  filed under the Exchange Act with the  Securities and Exchange
                  Commission.

         All  documents  filed by the  Registrant  pursuant to  Sections  13(a),
13(c),  14 and 15(d) of the Exchange Act subsequent to the date hereof and prior
to the filing of a post-effective  amendment which indicates that all securities
offered have been sold or which deregisters all securities then remaining unsold
shall be deemed to be incorporated by reference in this  Registration  Statement
and to be a part hereof from the date of filing of such documents.

Item 4.  Description of Securities.
- -------  --------------------------

         Not Applicable.

Item 5.  Interests of Named Experts and Counsel.
- -------  ---------------------------------------

         Not Applicable.

Item 6.  Indemnification of Directors and Officers.
- -------  ------------------------------------------

         The Registrant's  Articles of  Incorporation,  as amended (the "Amended
Articles"),  eliminate, subject to certain exceptions, the personal liability of
directors  to the  Registrant  or its  stockholders  for  monetary  damages  for
breaches of fiduciary  duties as directors to the extent permitted by state law.
The Amended  Articles do not provide for the  elimination  of, or any limitation
on, the personal liability of a director (i) for a breach of the director's duty
of loyalty,  (ii)  engaged in a  transaction  from which he receives an improper
benefit,  (iii) for  intentional  misconduct  or knowing  violation of law, (iv)
found not to have acted in good faith, (v) engaged

in an act related to an unlawful stock repurchase or payment of dividend or (vi)
where liability is prescribed by law. These  provisions of the Amended  Articles
may limit the remedies  available to a  stockholder  in the event of breaches of
any director's duties to such stockholder or the Registrant.

         The  Registrant's  Amended and Restated  Bylaws (the "Amended  Bylaws")
include  provisions for mandatory  indemnification of its officers and directors
to the  maximum  extent  provided  under  the  Texas  Business  Corporation  Act
("TBCA").  To the extent  permitted  under the TBCA,  the Amended Bylaws provide
that no officer or director  shall be liable to the Company for any action taken
or  omitted  to be taken by him as a  director  or  officer  if such  person (i)
exercised  the same  degree  of care and skill as a prudent  person  would  have
exercised  under  similar  circumstances  or (ii) took or  omitted  to take such
action in reliance  upon  advice of counsel  for the Company or upon  statements
made or information furnished by directors,  officers,  employees,  or agents of
the Company, which he had no reasonable grounds to disbelieve.  In addition, the
Amended  Bylaws provide that directors and officers shall be paid or reimbursed,
to the fullest extent provided under the TBCA, for reasonable  expenses incurred
by such director or officer in connection with certain  proceedings,  in advance
of the final disposition of such proceeding.

         Article 2.02-1 of the TBCA generally permits a corporation to indemnify
a person who was, is, or is threatened to be a named  defendant or respondent in
a  proceeding  because  the  person  was or is a  director  or  officer if it is
determined that such person (1) conducted  himself in good faith; (2) reasonably
believed  (a) in the case of conduct in his  official  capacity as a director or
officer of the  corporation,  that his  conduct  was in the  corporation's  best
interests, or (b) in the case of other situations, that his conduct was at least
not  opposed to the  corporation's  best  interests;  and (3) in the case of any
criminal  proceeding,  had no  reasonable  cause  to  believe  his  conduct  was
unlawful.  In addition,  the TBCA requires a corporation to indemnify a director
or officer for any action that such director or officer successfully defended on
the merits.

         The Registrant has entered into indemnification agreements with each of
its directors  and officers.  The  indemnification  agreements  provide that the
Registrant  will pay  certain  amounts  incurred  by a  director  or  officer in
connection  with any civil or criminal  action or  proceeding  and  specifically
including actions by or in the name of the Registrant  (derivative  suits) where
the  individual's  involvement  is by  reason  of the  fact  that he is or was a
director or officer.  Such amounts  include,  to the maximum extent permitted by
law, attorney's fees, judgments, civil or criminal fines, settlement amounts and
other expenses customarily included in connection with legal proceedings.  Under
the  indemnification   agreements,  a  director  or  officer  will  not  receive
indemnification if he is found not to have acted in good faith in the reasonable
belief that his action was in the best interests of the Registrant.

         The  Registrant  has  also  purchased  and  maintains   director's  and
officer's liability insurance for each of its officers and directors.

         Insofar as indemnification for liabilities arising under the Securities
Act of 1933,  as amended (the  "Securities  Act") may be permitted to directors,
officers or controlling persons of

the  Registrant  pursuant  to  the  Registrant's  By-Laws,  or  otherwise,   the
Registrant  has  been  informed  that  in the  opinion  of the  Commission  such
indemnification  is against public policy as expressed in the Securities Act and
is therefore unenforceable.

Item 7.  Exemption from Registration Claimed.
- -------  ------------------------------------

         Not Applicable.

Item 8.  Exhibits.
- -------  ---------

Number          Description
- ------          -----------

4.1*     Specimen  Common  Stock  Certificate  (Filed  as  Exhibit  4.B  to  the
         Registrant's   Registration   Statement   on   Form   S-8   (File   No.
         33-22900-FW)).

4.2*     Form of Common  Stock  Purchase  Warrant  used in  connection  with the
         issuance of warrants to purchase an aggregate  of  1,000,000  shares of
         the Registrant's Common Stock, $.003 par value (Filed as Exhibit 4.2 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1996).

4.3*     Articles  of  Incorporation  of the  Registrant,  as amended  (Filed as
         Exhibit 3.1 to the  Registrant's  Quarterly Report on Form 10-Q for the
         quarter ended August 31, 1997).

4.4*     Amended and Restated By-Laws of the Registrant (Filed as Exhibit 3.2 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         March 31, 1998).

4.5*     Form  of  Subscription  Agreement  used in  connection  with  Rule  506
         offering in the aggregate amount of $1,080,000 (Filed as Exhibit 4.5 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1997).

4.6*     Form  of  Subscription  Agreement  used in  connection  with  Rule  506
         offering in the aggregate  amount of $882,500  (Filed as Exhibit 4.6 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1997).

4.7*     Form of Common Stock Purchase Warrant issued to a consultant, Howard R.
         Baer,  in  August  1997  (Filed  as  Exhibit  4.7 to  the  Registrant's
         Quarterly Report on Form 10-Q for the quarter ended August 31, 1997).

4.8*     Common  Stock  Purchase  Warrant  issued to Howard R. Baer's  designee,
         Kevin C. Baer, in August 1997 (Filed as Exhibit 4.8 to the Registrant's
         Quarterly Report on Form 10-Q for the quarter ended August 31, 1997).

4.9*     Subscription  Agreement  used in Rule  506  offering  in the  aggregate
         amount  of  $5,276,250  (Filed  as  Exhibit  4.9  to  the  Registrant's
         Registration Statement on Form S-1 (File No. 333-40649)).

4.11*    Common  Stock  Purchase  Warrant  issued  to a  consultant's  designee,
         Irvington  International  Limited,  in November  1997 (Filed as Exhibit
         4.11 to the Registrant's Registration Statement on Form S-1 (File No.
         333-40649)).

5        Legal Opinion of Brown, Rudnick, Freed & Gesmer.

23.1     Consent of Brown,  Rudnick,  Freed & Gesmer  (contained  in its opinion
         filed as Exhibit 5).

23.2     Consent of Wolinetz, Gottlieb & Lafazan, P.C.

24       Power of Attorney  (included on the Signature Page of this Registration
         Statement).

99.1*    ConSyGen,  Inc. 1996 Non-Qualified Stock Option Plan. (Filed as Exhibit
         10.7 to the Registrant's  quarterly report on Form 10-Q for the quarter
         ended August 31, 1996).

99.2*    ConSyGen,  Inc.  1997 Amended and Restated  Non-Qualified  Stock Option
         Plan. (Filed as Exhibit 10.8 to the Registrant's Registration Statement
         on Form S-1 (File No. 333-40649)).

- -------------------

*        Not filed herewith. In accordance with Rule 411 promulgated pursuant to
         the Securities Act, reference is made to the documents previously filed
         with the Commission, which are incorporated by reference herein.

Item 9.  Undertakings.
- -------  -------------

(a)     The undersigned Registrant hereby undertakes:

        (1) To file,  during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement:

                  (i) To include any prospectus  required by Section 10(a)(3) of
the Securities Act;

                  (ii) To reflect in the  prospectus any facts or events arising
after the  effective  date of the  Registration  Statement  (or the most  recent
post-effective  amendment  thereof)  which,  individually  or in the  aggregate,
represent a fundamental  change in the information set forth in the Registration
Statement;

                  (iii)To include any material  information  with respect to the
plan of distribution not previously  disclosed in the Registration  Statement or
any material change to such information in this Registration Statement;

                  Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do
not  apply  if the  information  required  to be  included  in a  post-effective
amendment by those  paragraphs  is contained  in periodic  reports  filed by the
Registrant  pursuant to Section 13 or Section 15(d) of the  Securities  Exchange
Act that are incorporated by reference in this Registration Statement.

         (2) That,  for the  purpose  of  determining  any  liability  under the
Securities  Act,  each  post-effective  amendment  shall be  deemed  to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities  at the time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

(b)  The  undersigned   Registrant  hereby  undertakes  that,  for  purposes  of
determining  any  liability  under  the  Securities  Act,  each  filing  of  the
Registrant's  annual  report  pursuant to Section  13(a) or Section 15(d) of the
Securities  Exchange Act that is incorporated  by reference in the  Registration
Statement  shall be deemed to be a new  registration  statement  relating to the
securities  offered  therein,  and the offering of such  securities at that time
shall be deemed to be the initial bona fide offering thereof.

(c) Insofar as indemnification  for liabilities arising under the Securities Act
may  be  permitted  to  directors,  officers  and  controlling  persons  of  the
Registrant  pursuant to the  Registrant's  Amended  Articles  of  Incorporation,
Amended and Restated By-Laws, or otherwise, the Registrant has been advised that
in the opinion of the Securities and Exchange Commission such indemnification is
against  public  policy as expressed in the  Securities  Act and is,  therefore,
unenforceable.  In the  event  that a claim  for  indemnification  against  such
liabilities  (other than the payment by the  Registrant of expenses  incurred or
paid by a  director,  officer or  controlling  person of the  Registrant  in the
successful  defense of any  action,  suit or  proceeding)  is  asserted  by such
director,  officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether such  indemnification  by it is against public
policy as  expressed  in the  Securities  Act and will be  governed by the final
adjudication of such issue.

                                   SIGNATURES

        The  Registrant.  Pursuant to the  requirements of the Securities Act of
1933, as amended,  the Registrant  certifies  that it has reasonable  grounds to
believe  that it meets all of the  requirements  for  filing on Form S-8 and has
duly  caused  this  Registration  Statement  to be signed  on its  behalf by the
undersigned,  thereunto duly  authorized,  in the City of Phoenix,  Arizona,  on
April 29, 1998.

                                        CONSYGEN, INC.

                                        By:  /s/ Ronald I. Bishop
                                            -------------------------
                                             Ronald I. Bishop
                                             President

                                POWER OF ATTORNEY

        KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below constitutes and appoints Ronald I. Bishop and John Stephen Kelly, and each
of them  (with  full  power to each of them to act  alone),  his true and lawful
attorneys-in-fact   and   agents,   with   full   power  of   substitution   and
resubstitution,  for  him  and in his  name,  place  and  stead,  in any and all
capacities, to sign any or all amendments (including post-effective  amendments)
to this Registration Statement,  and to file the same, with all exhibits thereto
and other  documents in connection  therewith,  with the Securities and Exchange
Commission,  granting unto said  attorneys-in-fact and agents, and each of them,
full  power  and  authority  to do and  perform  each and  every  act and  thing
requisite and  necessary to be done in and about the  premises,  as fully to all
intents and  purposes as he might or could do in person,  hereby  ratifying  and
confirming all that said  attorneys-in-fact and agents, or any of them, or their
substitutes, may lawfully do or cause to be done by virtue hereof.

      Pursuant to the  requirements  of the  Securities Act of 1933, as amended,
this  Registration  Statement  has been signed by the  following  persons in the
capacities and on the dates indicated.


                   Signature                                 Title                                    Date
                   ---------                                 -----                                    ----
                                                                                 
        /s/ Robert L. Stewart               Chairman of the Board                       April 29, 1998
- ------------------------------------
      Robert L. Stewart

        /s/ Ronald I. Bishop                President, Chief Executive                  April 29, 1998
- ------------------------------------        Officer and Director         
      Ronald I. Bishop                      (Principal Executive Officer)

         /s/ Rajesh K. Kapur                Vice President and Chief Financial          April 29, 1998
- ------------------------------------        Officer (Principal Financial Officer)
      Rajesh K. Kapur                       

      /s/ John Stephen Kelly                Vice President and General                  April 29, 1998
- ------------------------------------        Counsel (Principal Executive Officer)
      John Stephen Kelly                    

         /s/ Kenneth Harvey                 Controller                                  April 29, 1998
- ------------------------------------        (Principal Accounting Officer)
      Kenneth Harvey                        

     /s/ Andrew Lee                         Director                                    April 30, 1998
- ------------------------------------
      Andrew Lee

                                            Director                                    April __, 1998
- ------------------------------------        
      Richard L. Ruth

                                            Director                                    April __, 1998
- ------------------------------------        
      Daniel G. Queyssac


                                  EXHIBIT INDEX


Exhibit                                                                                                  Sequential
Number                                                                                                     Page No.
- ------                                                                                                     --------

                                                                                                      
4.1      Specimen  Common  Stock  Certificate  (Filed  as  Exhibit  4.B  to  the
         Registrant's  Registration Statement on Form S-8 (File No. 33-22900-FW)).                          *

4.2      Form of Common  Stock  Purchase  Warrant  used in  connection  with the
         issuance of warrants to purchase an aggregate  of  1,000,000  shares of
         the Registrant's Common Stock, $.003 par value (Filed as Exhibit 4.2 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1996).                                                                                  *

4.3      Articles  of  Incorporation  of the  Registrant,  as amended  (Filed as
         Exhibit 3.1 to the  Registrant's  Quarterly Report on Form 10-Q for the
         quarter ended August 31, 1997).                                                                    *

4.4      Amended and Restated By-Laws of the Registrant (Filed as Exhibit 3.2 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         March 31, 1998).                                                                                   *

4.5      Form  of  Subscription  Agreement  used in  connection  with  Rule  506
         offering in the aggregate amount of $1,080,000 (Filed as Exhibit 4.5 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1997).                                                                                  *

4.6      Form  of  Subscription  Agreement  used in  connection  with  Rule  506
         offering in the aggregate  amount of $882,500  (Filed as Exhibit 4.6 to
         the  Registrant's  Quarterly  Report on Form 10-Q for the quarter ended
         August 31, 1997).                                                                                  *

4.7      Form of Common Stock Purchase Warrant issued to a consultant, Howard R.
         Baer,  in  August  1997  (Filed  as  Exhibit  4.7 to  the  Registrant's
         Quarterly Report on Form 10-Q for the quarter ended August 31, 1997).                              *

4.8      Common  Stock  Purchase  Warrant  issued to Howard R. Baer's  designee,
         Kevin C. Baer, in August 1997 (Filed as Exhibit 4.8 to the Registrant's
         Quarterly Report on Form 10-Q for the quarter ended August 31, 1997).                              *

4.9      Subscription  Agreement  used in Rule  506  offering  in the  aggregate
         amount  of  $5,276,250  (Filed  as  Exhibit  4.9  to  the  Registrant's
         Registration Statement on Form S-1 (File No. 333-40649)).                                          *

4.11     Common  Stock  Purchase  Warrant  issued  to a  consultant's  designee,
         Irvington  International  Limited,  in November  1997 (Filed as Exhibit
         4.11 to the Registrant's  Registration  Statement on Form S-1 (File No.
         333-40649)).                                                                                       *

5        Legal Opinion of Brown, Rudnick, Freed & Gesmer.

23.1     Consent of Brown, Rudnick, Freed & Gesmer.                                                        **

23.2     Consent of Wolinetz, Gottlieb & Lafazan, P.C.

24       Power of Attorney.                                                                                ***

99.1*    ConSyGen,  Inc. 1996 Non-Qualified Stock Option Plan. (Filed as Exhibit
         10.7 to the Registrant's  quarterly report on Form 10-Q for the quarter
         ended August 31, 1996).

99.2*    ConSyGen,  Inc.  1997 Amended and Restated  Non-Qualified  Stock Option
         Plan. (Filed as Exhibit 10.8 to the Registrant's Registration Statement
         on Form S-1 (File No. 333-40649)).


- -------------------

*        Not filed herewith. In accordance with Rule 411 promulgated pursuant to
         the  Securities  Act of  1933,  reference  is  made  to  the  documents
         previously  filed  with  the  Commission,  which  are  incorporated  by
         reference herein.

**       Contained in Exhibit 5.

***      Included on the Signature Page of this Registration Statement.